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Search of human proteins with 42558270
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|42558270 HEAT repeat containing 4 [Homo sapiens]
(979 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|42558270 HEAT repeat containing 4 [Homo sapiens] 1954 0.0
gi|76253680 hypothetical protein LOC256957 [Homo sapiens] 37 0.091
gi|20532340 angiopoietin 1 [Homo sapiens] 35 0.34
gi|24797086 importin 5 [Homo sapiens] 34 0.59
gi|54607053 GCN1 general control of amino-acid synthesis 1-like ... 34 0.77
gi|112420977 TBP-interacting protein isoform 2 [Homo sapiens] 33 1.0
gi|156766050 AHNAK nucleoprotein 2 [Homo sapiens] 33 1.0
gi|32967514 neurofibromin 2 isoform 7 [Homo sapiens] 33 1.3
gi|32967254 neurofibromin 2 isoform 2 [Homo sapiens] 33 1.3
gi|32967266 neurofibromin 2 isoform 2 [Homo sapiens] 33 1.3
gi|32967264 neurofibromin 2 isoform 7 [Homo sapiens] 33 1.3
gi|32967262 neurofibromin 2 isoform 6 [Homo sapiens] 33 1.3
gi|32967260 neurofibromin 2 isoform 5 [Homo sapiens] 33 1.3
gi|32451486 neurofibromin 2 isoform 2 [Homo sapiens] 33 1.3
gi|4557795 neurofibromin 2 isoform 1 [Homo sapiens] 33 1.3
gi|5454180 zinc finger protein 193 [Homo sapiens] 33 1.7
gi|83716024 kinesin family member 21B [Homo sapiens] 32 2.2
gi|91982772 mucin 17 [Homo sapiens] 32 2.9
gi|81295809 pericentrin [Homo sapiens] 32 3.8
gi|150170670 piccolo isoform 2 [Homo sapiens] 32 3.8
gi|150378539 piccolo isoform 1 [Homo sapiens] 32 3.8
gi|239047795 pleckstrin homology domain containing, family A mem... 31 5.0
gi|223278337 C-type lectin domain family 4, member M isoform 12 ... 31 5.0
gi|223278335 C-type lectin domain family 4, member M isoform 2 [... 31 5.0
gi|59891448 rapamycin-insensitive companion of mTOR [Homo sapiens] 31 5.0
gi|223278353 C-type lectin domain family 4, member M isoform 3 [... 31 5.0
gi|223278350 C-type lectin domain family 4, member M isoform 8 [... 31 5.0
gi|42542390 C-type lectin domain family 4, member M isoform 1 [H... 31 5.0
gi|224451124 neurobeachin-like 1 isoform 3 [Homo sapiens] 31 5.0
gi|67782311 superkiller viralicidic activity 2-like homolog [Hom... 31 5.0
>gi|42558270 HEAT repeat containing 4 [Homo sapiens]
Length = 979
Score = 1954 bits (5062), Expect = 0.0
Identities = 979/979 (100%), Positives = 979/979 (100%)
Query: 1 MVFFSSQYRLHRKSQYLKMAAANLTFSQEVVWQRGLPSIPYSQYSFDHLYNTNDIIHTPQ 60
MVFFSSQYRLHRKSQYLKMAAANLTFSQEVVWQRGLPSIPYSQYSFDHLYNTNDIIHTPQ
Sbjct: 1 MVFFSSQYRLHRKSQYLKMAAANLTFSQEVVWQRGLPSIPYSQYSFDHLYNTNDIIHTPQ 60
Query: 61 IRKARPQKPVSFKFLGSSSPLTGDTSLAVKTESSANPEKKLKKSKPASTVREAPRPLIHH 120
IRKARPQKPVSFKFLGSSSPLTGDTSLAVKTESSANPEKKLKKSKPASTVREAPRPLIHH
Sbjct: 61 IRKARPQKPVSFKFLGSSSPLTGDTSLAVKTESSANPEKKLKKSKPASTVREAPRPLIHH 120
Query: 121 PCMHPDMLGRPPSLDVNLEEREAWLLPPEKEARAWEATVLEKLNERTARWIQSKRPRRPG 180
PCMHPDMLGRPPSLDVNLEEREAWLLPPEKEARAWEATVLEKLNERTARWIQSKRPRRPG
Sbjct: 121 PCMHPDMLGRPPSLDVNLEEREAWLLPPEKEARAWEATVLEKLNERTARWIQSKRPRRPG 180
Query: 181 ASPNKWQSFLRQQYDWSHIRDELTSASDLELLKQLEAEETAEFEDQSVILPPQEKKKPEL 240
ASPNKWQSFLRQQYDWSHIRDELTSASDLELLKQLEAEETAEFEDQSVILPPQEKKKPEL
Sbjct: 181 ASPNKWQSFLRQQYDWSHIRDELTSASDLELLKQLEAEETAEFEDQSVILPPQEKKKPEL 240
Query: 241 LLPVYYRLPSYFQQAETVEIMPGNKSTEDIHEKTSLSQPQTQSYFRQVTPRAGKFAYSTD 300
LLPVYYRLPSYFQQAETVEIMPGNKSTEDIHEKTSLSQPQTQSYFRQVTPRAGKFAYSTD
Sbjct: 241 LLPVYYRLPSYFQQAETVEIMPGNKSTEDIHEKTSLSQPQTQSYFRQVTPRAGKFAYSTD 300
Query: 301 NTFEQEIYFDEVQIIHQIGAKRDQIVLENLNRYNKQLSKVFPETPEKWSAQAIPEASYRP 360
NTFEQEIYFDEVQIIHQIGAKRDQIVLENLNRYNKQLSKVFPETPEKWSAQAIPEASYRP
Sbjct: 301 NTFEQEIYFDEVQIIHQIGAKRDQIVLENLNRYNKQLSKVFPETPEKWSAQAIPEASYRP 360
Query: 361 VQGALRWTALPTPAKDMLLQVGEKDVPIKTRRLKKQAKSLQEDVTWELVVLRRMLKEWKT 420
VQGALRWTALPTPAKDMLLQVGEKDVPIKTRRLKKQAKSLQEDVTWELVVLRRMLKEWKT
Sbjct: 361 VQGALRWTALPTPAKDMLLQVGEKDVPIKTRRLKKQAKSLQEDVTWELVVLRRMLKEWKT 420
Query: 421 AWALIIEWHHETVENLLQSLGDLHDDVRIKAITTCATAALERPRIATSQRDSDKTIQDLP 480
AWALIIEWHHETVENLLQSLGDLHDDVRIKAITTCATAALERPRIATSQRDSDKTIQDLP
Sbjct: 421 AWALIIEWHHETVENLLQSLGDLHDDVRIKAITTCATAALERPRIATSQRDSDKTIQDLP 480
Query: 481 EVLLPALEAALCDKNAHVRMAAAICQYAIQSHNPLARNIMQTALLKGNSVDSWAAAQCLA 540
EVLLPALEAALCDKNAHVRMAAAICQYAIQSHNPLARNIMQTALLKGNSVDSWAAAQCLA
Sbjct: 481 EVLLPALEAALCDKNAHVRMAAAICQYAIQSHNPLARNIMQTALLKGNSVDSWAAAQCLA 540
Query: 541 LEGTATYPVIKRILHQLFTKKNEDTEEQSYILLSYLSEKTTLIHTMLAVELNSCQWKNRI 600
LEGTATYPVIKRILHQLFTKKNEDTEEQSYILLSYLSEKTTLIHTMLAVELNSCQWKNRI
Sbjct: 541 LEGTATYPVIKRILHQLFTKKNEDTEEQSYILLSYLSEKTTLIHTMLAVELNSCQWKNRI 600
Query: 601 VACQAFSRISGNVCLDMKHKLIQLMWNDWNKEVRRAAAQALGQMSLGKEVHDIIRVKLGQ 660
VACQAFSRISGNVCLDMKHKLIQLMWNDWNKEVRRAAAQALGQMSLGKEVHDIIRVKLGQ
Sbjct: 601 VACQAFSRISGNVCLDMKHKLIQLMWNDWNKEVRRAAAQALGQMSLGKEVHDIIRVKLGQ 660
Query: 661 GNSQERVEALYLIGELKLMTAKLLPSFLHCFSDDFTAVRRAACLAAGALQIRDKMVLECL 720
GNSQERVEALYLIGELKLMTAKLLPSFLHCFSDDFTAVRRAACLAAGALQIRDKMVLECL
Sbjct: 661 GNSQERVEALYLIGELKLMTAKLLPSFLHCFSDDFTAVRRAACLAAGALQIRDKMVLECL 720
Query: 721 LNLMQRDPYWKIKAFAIRALGQIGQVSPELTDLLLWAIHYEESPGVRLEACRSILALKLQ 780
LNLMQRDPYWKIKAFAIRALGQIGQVSPELTDLLLWAIHYEESPGVRLEACRSILALKLQ
Sbjct: 721 LNLMQRDPYWKIKAFAIRALGQIGQVSPELTDLLLWAIHYEESPGVRLEACRSILALKLQ 780
Query: 781 GDRVRDTFLDVLLLENHDAVLKEMYQTMKILNLGNEGNQEMLQEIKNRIKTLSQKDLLTH 840
GDRVRDTFLDVLLLENHDAVLKEMYQTMKILNLGNEGNQEMLQEIKNRIKTLSQKDLLTH
Sbjct: 781 GDRVRDTFLDVLLLENHDAVLKEMYQTMKILNLGNEGNQEMLQEIKNRIKTLSQKDLLTH 840
Query: 841 KILKLEMVMGKVREEAKRVYLKPKGEQGPLTLQTLLQETFQDEMVLPRRPSEVCDTEAVI 900
KILKLEMVMGKVREEAKRVYLKPKGEQGPLTLQTLLQETFQDEMVLPRRPSEVCDTEAVI
Sbjct: 841 KILKLEMVMGKVREEAKRVYLKPKGEQGPLTLQTLLQETFQDEMVLPRRPSEVCDTEAVI 900
Query: 901 KPVKPRAPNPWLQSSVPGLTTRSKVRSSLVKDLRTSPEKRIAVGPFRSDYPALYLGKFSE 960
KPVKPRAPNPWLQSSVPGLTTRSKVRSSLVKDLRTSPEKRIAVGPFRSDYPALYLGKFSE
Sbjct: 901 KPVKPRAPNPWLQSSVPGLTTRSKVRSSLVKDLRTSPEKRIAVGPFRSDYPALYLGKFSE 960
Query: 961 RTFFSPIMSSPSGKKGAHL 979
RTFFSPIMSSPSGKKGAHL
Sbjct: 961 RTFFSPIMSSPSGKKGAHL 979
>gi|76253680 hypothetical protein LOC256957 [Homo sapiens]
Length = 570
Score = 37.0 bits (84), Expect = 0.091
Identities = 47/200 (23%), Positives = 95/200 (47%), Gaps = 16/200 (8%)
Query: 621 LIQLMWNDWNKEVRRAAAQALGQMS-LGKEVHDIIRVKLGQGNSQERVEAL-YLIGELKL 678
++Q + + E AA LG + V + + L QG +R++AL L+ + +
Sbjct: 265 VLQTLIKKSSSEASLEAALCLGFLRPCSNMVQEFLLQCLCQGLKTQRMKALRMLVKVMHV 324
Query: 679 MTAKLLPSFLH--CFS----DDFTAVRRAACLAAGALQIRDKMVLECLLNLMQR----DP 728
+A ++ + L C S D F A + + G QI+ + + E NL++R +P
Sbjct: 325 HSAPVIKAILDQLCSSSVLEDRFEATQMLKTI--GLEQIQAQGLEELTFNLLRRKTHNEP 382
Query: 729 YWKIKAFAIRALGQIGQVSPELTDLLLWAIHYEESPGVRLEACRSILALKLQGDRVRDTF 788
+ ++ + + ++ ++ P + +L+ + ++ R EA S+ L ++ +V
Sbjct: 383 FLAVRQAVAQTVEEL-KLKPTMMNLVEAQLMNPDATA-RQEAVISLGVLGIRSPQVFHLL 440
Query: 789 LDVLLLENHDAVLKEMYQTM 808
LD+L ENH AV K + +T+
Sbjct: 441 LDLLDAENHQAVKKSLQETL 460
Score = 32.3 bits (72), Expect = 2.2
Identities = 23/68 (33%), Positives = 36/68 (52%), Gaps = 2/68 (2%)
Query: 702 ACLAAGALQIRDKMVLECLLNLMQRDPYWKIKAFAIRALGQIGQVSPELTDLLLWAIHYE 761
A A G L+I DK V+E L + Q P K+K A R L +G ++ + L+ + E
Sbjct: 168 AAQALGCLRISDKFVMEALQQVAQTGPE-KVKYEAYRTLAILGCLNKHVIRALIKQLK-E 225
Query: 762 ESPGVRLE 769
++ G R+E
Sbjct: 226 KNEGQRME 233
>gi|20532340 angiopoietin 1 [Homo sapiens]
Length = 498
Score = 35.0 bits (79), Expect = 0.34
Identities = 24/86 (27%), Positives = 45/86 (52%), Gaps = 11/86 (12%)
Query: 819 QEMLQEIKNRIKTLSQKDLLTHKILKLEMVMGKVREEAKRVYLKPKGEQGPLTLQTLLQE 878
+++LQ+ +K + LL HKIL++E GK +EE + + + QG +T QT + +
Sbjct: 175 KQLLQQTNEILKIHEKNSLLEHKILEME---GKHKEELDTLKEEKENLQGLVTRQTYIIQ 231
Query: 879 TFQDEM--------VLPRRPSEVCDT 896
+ ++ VL ++ E+ DT
Sbjct: 232 ELEKQLNRATTNNSVLQKQQLELMDT 257
>gi|24797086 importin 5 [Homo sapiens]
Length = 1115
Score = 34.3 bits (77), Expect = 0.59
Identities = 34/134 (25%), Positives = 62/134 (46%), Gaps = 24/134 (17%)
Query: 696 TAVRRAACLAAGALQIRDKMVLECLLNLMQRDPYWKIKAFAIRALGQIGQ--------VS 747
+A+ R AC G L + M+ E ++ ++Q +P WK + + AL IG+ +
Sbjct: 359 SALDRMACGLGGKLVL--PMIKEHIMQMLQ-NPDWKYRHAGLMALSAIGEGCHQQMEGIL 415
Query: 748 PELTDLLLWAIHYEESPGVRLEACRSILALKLQGDRVRDTFLDVLLLENHDAVLKEMYQT 807
E+ + +L + + P VR AC ++ G D F + H+ V+ + QT
Sbjct: 416 NEIVNFVLLFLQ-DPHPRVRYAACNAV------GQMATD-FAPGFQKKFHEKVIAALLQT 467
Query: 808 MKILNLGNEGNQEM 821
M+ ++GNQ +
Sbjct: 468 ME-----DQGNQRV 476
>gi|54607053 GCN1 general control of amino-acid synthesis 1-like 1
[Homo sapiens]
Length = 2671
Score = 33.9 bits (76), Expect = 0.77
Identities = 31/101 (30%), Positives = 44/101 (43%), Gaps = 14/101 (13%)
Query: 662 NSQERVEALYLIGELKLMTAKL--------LPSFLHCFSDDFTAVRRAACLAAGALQIR- 712
N + R AL+ L M KL LP L CF D VR AA A A+
Sbjct: 1431 NFRRREGALFAFEMLCTMLGKLFEPYVVHVLPHLLLCFGDGNQYVREAADDCAKAVMSNL 1490
Query: 713 ----DKMVLECLLNLMQRDPYWKIKAFAIRALGQIGQVSPE 749
K+VL LL ++ + W+ KA ++ LG + +P+
Sbjct: 1491 SAHGVKLVLPSLLAALEEES-WRTKAGSVELLGAMAYCAPK 1530
>gi|112420977 TBP-interacting protein isoform 2 [Homo sapiens]
Length = 1119
Score = 33.5 bits (75), Expect = 1.0
Identities = 44/183 (24%), Positives = 80/183 (43%), Gaps = 19/183 (10%)
Query: 630 NKEVRRAAAQALGQMSLGKEVHDIIRVKLGQGNSQERVEALYLIGELKLMTAKLLPSFLH 689
+++VR AA+ ALG++ G + D + L Q ++ R + L L+ L+ P L
Sbjct: 781 SEDVRAAASYALGRVGAG-SLPDFLPFLLEQIEAEPRRQYL-LLHSLREALGAAQPDSLK 838
Query: 690 CFSDDFTAVRRAACLAAGALQIRDKMVLECLLNLMQRDPYWKIKAFAIRALGQIGQVSPE 749
+++D A+ C GA + +V EC+ L+ +P + + R Q+ P
Sbjct: 839 PYAEDIWALLFQRC--EGAEEGTRGVVAECIGKLVLVNPSFLLP----RLRKQLAAGRPH 892
Query: 750 LTDLLLWAIHY--EESPGVRLEACRSILALKLQGDRVRDTFLDVLLLENHDAVLKEMYQT 807
++ A+ + + P +S +A+ + VRD D+L L +YQ
Sbjct: 893 TRSTVITAVKFLISDQPHPIDPLLKSFIAVHNKPSLVRDLLDDILPL---------LYQE 943
Query: 808 MKI 810
KI
Sbjct: 944 TKI 946
>gi|156766050 AHNAK nucleoprotein 2 [Homo sapiens]
Length = 5795
Score = 33.5 bits (75), Expect = 1.0
Identities = 51/222 (22%), Positives = 82/222 (36%), Gaps = 11/222 (4%)
Query: 65 RPQKPVSFKFLGSSSPLTGDTSLAVKTESSANPEKKLKKSKPASTVREAPRPLIHHPCMH 124
+P F+ + SS + G +L + S +PA + P
Sbjct: 5567 QPDTGEPFEMISSSVNVLGQQTLTFEVPSGHQLADSCSDEEPAEILEFPPDDSQEATTPL 5626
Query: 125 PDMLGRPPSLDVNLEEREAWL-LPPEKEARAWEATVLEKLNE-RTARWIQSKRPRRPGAS 182
D P + + W LP + + + T ++ N+ + + IQ++ RP A
Sbjct: 5627 ADEGRAPKDKPESKKSGLLWFWLPNIGFSSSVDETGVDSKNDVQRSAPIQTQPEARPEAE 5686
Query: 183 -PNK-----WQSFLRQQYDWSHIRDELTSASDLELLKQLEAEETAEFEDQSVILPPQEKK 236
P K W F + + S + ++ EL +Q EET F D P+EK+
Sbjct: 5687 LPKKQEKAGWFRFPKLGFSSSPTKKSKSTEDGAELEEQKLQEETITFFDARESFSPEEKE 5746
Query: 237 KPELLLPVYYRLPS---YFQQAETVEIMPGNKSTEDIHEKTS 275
+ EL+ PV L S A T I+P D K S
Sbjct: 5747 EGELIGPVGTGLDSRVMVTSAARTELILPEQDRKADDESKGS 5788
>gi|32967514 neurofibromin 2 isoform 7 [Homo sapiens]
Length = 507
Score = 33.1 bits (74), Expect = 1.3
Identities = 34/129 (26%), Positives = 63/129 (48%), Gaps = 14/129 (10%)
Query: 816 EGNQEMLQEIKNRIKTLSQKDLLTHKILKLEMVMGKVREEAKRVYLKPKGEQGPLTLQTL 875
E QEM + I+T +K L+ K+L+ E++ K+ EE++R + +Q L+
Sbjct: 321 EAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESER--RAKEADQ----LKQD 374
Query: 876 LQETFQDEMVLPRRPSEVCDTEAVIKPVKP-RAPNPWLQSSVPGLTTRSKVRSSLVKDLR 934
LQE + E ++ E+ T+ P+ P AP P P + + + + SL D +
Sbjct: 375 LQEAREAERRAKQKLLEIA-TKPTYPPMNPIPAPLP------PDIPSFNLIGDSLSFDFK 427
Query: 935 TSPEKRIAV 943
+ KR+++
Sbjct: 428 DTDMKRLSM 436
>gi|32967254 neurofibromin 2 isoform 2 [Homo sapiens]
Length = 590
Score = 33.1 bits (74), Expect = 1.3
Identities = 34/129 (26%), Positives = 63/129 (48%), Gaps = 14/129 (10%)
Query: 816 EGNQEMLQEIKNRIKTLSQKDLLTHKILKLEMVMGKVREEAKRVYLKPKGEQGPLTLQTL 875
E QEM + I+T +K L+ K+L+ E++ K+ EE++R + +Q L+
Sbjct: 404 EAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESER--RAKEADQ----LKQD 457
Query: 876 LQETFQDEMVLPRRPSEVCDTEAVIKPVKP-RAPNPWLQSSVPGLTTRSKVRSSLVKDLR 934
LQE + E ++ E+ T+ P+ P AP P P + + + + SL D +
Sbjct: 458 LQEAREAERRAKQKLLEIA-TKPTYPPMNPIPAPLP------PDIPSFNLIGDSLSFDFK 510
Query: 935 TSPEKRIAV 943
+ KR+++
Sbjct: 511 DTDMKRLSM 519
>gi|32967266 neurofibromin 2 isoform 2 [Homo sapiens]
Length = 590
Score = 33.1 bits (74), Expect = 1.3
Identities = 34/129 (26%), Positives = 63/129 (48%), Gaps = 14/129 (10%)
Query: 816 EGNQEMLQEIKNRIKTLSQKDLLTHKILKLEMVMGKVREEAKRVYLKPKGEQGPLTLQTL 875
E QEM + I+T +K L+ K+L+ E++ K+ EE++R + +Q L+
Sbjct: 404 EAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESER--RAKEADQ----LKQD 457
Query: 876 LQETFQDEMVLPRRPSEVCDTEAVIKPVKP-RAPNPWLQSSVPGLTTRSKVRSSLVKDLR 934
LQE + E ++ E+ T+ P+ P AP P P + + + + SL D +
Sbjct: 458 LQEAREAERRAKQKLLEIA-TKPTYPPMNPIPAPLP------PDIPSFNLIGDSLSFDFK 510
Query: 935 TSPEKRIAV 943
+ KR+++
Sbjct: 511 DTDMKRLSM 519
>gi|32967264 neurofibromin 2 isoform 7 [Homo sapiens]
Length = 507
Score = 33.1 bits (74), Expect = 1.3
Identities = 34/129 (26%), Positives = 63/129 (48%), Gaps = 14/129 (10%)
Query: 816 EGNQEMLQEIKNRIKTLSQKDLLTHKILKLEMVMGKVREEAKRVYLKPKGEQGPLTLQTL 875
E QEM + I+T +K L+ K+L+ E++ K+ EE++R + +Q L+
Sbjct: 321 EAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESER--RAKEADQ----LKQD 374
Query: 876 LQETFQDEMVLPRRPSEVCDTEAVIKPVKP-RAPNPWLQSSVPGLTTRSKVRSSLVKDLR 934
LQE + E ++ E+ T+ P+ P AP P P + + + + SL D +
Sbjct: 375 LQEAREAERRAKQKLLEIA-TKPTYPPMNPIPAPLP------PDIPSFNLIGDSLSFDFK 427
Query: 935 TSPEKRIAV 943
+ KR+++
Sbjct: 428 DTDMKRLSM 436
>gi|32967262 neurofibromin 2 isoform 6 [Homo sapiens]
Length = 549
Score = 33.1 bits (74), Expect = 1.3
Identities = 34/129 (26%), Positives = 63/129 (48%), Gaps = 14/129 (10%)
Query: 816 EGNQEMLQEIKNRIKTLSQKDLLTHKILKLEMVMGKVREEAKRVYLKPKGEQGPLTLQTL 875
E QEM + I+T +K L+ K+L+ E++ K+ EE++R + +Q L+
Sbjct: 363 EAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESER--RAKEADQ----LKQD 416
Query: 876 LQETFQDEMVLPRRPSEVCDTEAVIKPVKP-RAPNPWLQSSVPGLTTRSKVRSSLVKDLR 934
LQE + E ++ E+ T+ P+ P AP P P + + + + SL D +
Sbjct: 417 LQEAREAERRAKQKLLEIA-TKPTYPPMNPIPAPLP------PDIPSFNLIGDSLSFDFK 469
Query: 935 TSPEKRIAV 943
+ KR+++
Sbjct: 470 DTDMKRLSM 478
>gi|32967260 neurofibromin 2 isoform 5 [Homo sapiens]
Length = 548
Score = 33.1 bits (74), Expect = 1.3
Identities = 34/129 (26%), Positives = 63/129 (48%), Gaps = 14/129 (10%)
Query: 816 EGNQEMLQEIKNRIKTLSQKDLLTHKILKLEMVMGKVREEAKRVYLKPKGEQGPLTLQTL 875
E QEM + I+T +K L+ K+L+ E++ K+ EE++R + +Q L+
Sbjct: 362 EAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESER--RAKEADQ----LKQD 415
Query: 876 LQETFQDEMVLPRRPSEVCDTEAVIKPVKP-RAPNPWLQSSVPGLTTRSKVRSSLVKDLR 934
LQE + E ++ E+ T+ P+ P AP P P + + + + SL D +
Sbjct: 416 LQEAREAERRAKQKLLEIA-TKPTYPPMNPIPAPLP------PDIPSFNLIGDSLSFDFK 468
Query: 935 TSPEKRIAV 943
+ KR+++
Sbjct: 469 DTDMKRLSM 477
>gi|32451486 neurofibromin 2 isoform 2 [Homo sapiens]
Length = 590
Score = 33.1 bits (74), Expect = 1.3
Identities = 34/129 (26%), Positives = 63/129 (48%), Gaps = 14/129 (10%)
Query: 816 EGNQEMLQEIKNRIKTLSQKDLLTHKILKLEMVMGKVREEAKRVYLKPKGEQGPLTLQTL 875
E QEM + I+T +K L+ K+L+ E++ K+ EE++R + +Q L+
Sbjct: 404 EAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESER--RAKEADQ----LKQD 457
Query: 876 LQETFQDEMVLPRRPSEVCDTEAVIKPVKP-RAPNPWLQSSVPGLTTRSKVRSSLVKDLR 934
LQE + E ++ E+ T+ P+ P AP P P + + + + SL D +
Sbjct: 458 LQEAREAERRAKQKLLEIA-TKPTYPPMNPIPAPLP------PDIPSFNLIGDSLSFDFK 510
Query: 935 TSPEKRIAV 943
+ KR+++
Sbjct: 511 DTDMKRLSM 519
>gi|4557795 neurofibromin 2 isoform 1 [Homo sapiens]
Length = 595
Score = 33.1 bits (74), Expect = 1.3
Identities = 34/129 (26%), Positives = 63/129 (48%), Gaps = 14/129 (10%)
Query: 816 EGNQEMLQEIKNRIKTLSQKDLLTHKILKLEMVMGKVREEAKRVYLKPKGEQGPLTLQTL 875
E QEM + I+T +K L+ K+L+ E++ K+ EE++R + +Q L+
Sbjct: 404 EAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESER--RAKEADQ----LKQD 457
Query: 876 LQETFQDEMVLPRRPSEVCDTEAVIKPVKP-RAPNPWLQSSVPGLTTRSKVRSSLVKDLR 934
LQE + E ++ E+ T+ P+ P AP P P + + + + SL D +
Sbjct: 458 LQEAREAERRAKQKLLEIA-TKPTYPPMNPIPAPLP------PDIPSFNLIGDSLSFDFK 510
Query: 935 TSPEKRIAV 943
+ KR+++
Sbjct: 511 DTDMKRLSM 519
>gi|5454180 zinc finger protein 193 [Homo sapiens]
Length = 394
Score = 32.7 bits (73), Expect = 1.7
Identities = 38/143 (26%), Positives = 62/143 (43%), Gaps = 29/143 (20%)
Query: 760 YEESPGVRLEACRSILALKLQGDR----VRDTFLDVLLLENHDAVLKEMYQTMKILNLGN 815
Y+E+PG R EA + L Q R ++ LD+L+LE ++L + Q +
Sbjct: 60 YQETPGPR-EALTRLQELCYQWLRPHVSTKEQILDLLVLEQFLSILPKELQGWVREHCPE 118
Query: 816 EGNQE--MLQEIKNRIKTLSQKDLLTHKILKLEMVMGKVREEAKRVYLKPKGEQGPLTLQ 873
G + +L++++ + D H EMV + R+E + P EQ PLTLQ
Sbjct: 119 SGEEAVILLEDLEREL------DEPQH-----EMVAHRHRQEVLCKEMVPLAEQTPLTLQ 167
Query: 874 TLLQETFQDEMVLPRRPSEVCDT 896
+ P+ P CD+
Sbjct: 168 S-----------QPKEPQLTCDS 179
>gi|83716024 kinesin family member 21B [Homo sapiens]
Length = 1624
Score = 32.3 bits (72), Expect = 2.2
Identities = 46/206 (22%), Positives = 81/206 (39%), Gaps = 22/206 (10%)
Query: 796 NHDAVLKEMYQTMKILNLGNEGNQEMLQEIKNRIKTLSQKDLLTHKILKLEM-VMGKVRE 854
+++ L+EM + ++ L + + +L+ + L + ++ K ++ +M ++RE
Sbjct: 709 DYEKRLREMNRDLQKLQAAQKEHARLLKNQSRYERELKKLQAEVAEMKKAKVALMKQMRE 768
Query: 855 EAKR------------VYLKPKGEQGPLTLQTLLQETFQDEMVLPRRPSEVCDTEAVIKP 902
E +R LK + + ++ L + Q EMVL R+ EV + KP
Sbjct: 769 EQQRRRLVETKRNREIAQLKKEQRRQEFQIRALESQKRQQEMVLRRKTQEVSALRRLAKP 828
Query: 903 VKPRAPN------PWLQS--SVPGLTTRSKVRSSLVKDLRTSPEKRIAVGPFRSDYPALY 954
+ R P L S V TT S+ S + + F D+PA
Sbjct: 829 MSERVAGRAGLKPPMLDSGAEVSASTTSSEAESGARSVSSIVRQWNRKINHFLGDHPAPT 888
Query: 955 L-GKFSERTFFSPIMSSPSGKKGAHL 979
+ G R F +S S K A L
Sbjct: 889 VNGTRPARKKFQKKGASQSFSKAARL 914
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 32.0 bits (71), Expect = 2.9
Identities = 17/48 (35%), Positives = 23/48 (47%)
Query: 77 SSSPLTGDTSLAVKTESSANPEKKLKKSKPASTVREAPRPLIHHPCMH 124
S++P+ T +A TE+S+ P S P ST E PL P H
Sbjct: 1181 STTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRH 1228
Score = 31.6 bits (70), Expect = 3.8
Identities = 16/45 (35%), Positives = 23/45 (51%)
Query: 77 SSSPLTGDTSLAVKTESSANPEKKLKKSKPASTVREAPRPLIHHP 121
S++P+ +T L TE+S++P S P ST E PL P
Sbjct: 3243 STTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMP 3287
Score = 30.8 bits (68), Expect = 6.5
Identities = 16/45 (35%), Positives = 22/45 (48%)
Query: 77 SSSPLTGDTSLAVKTESSANPEKKLKKSKPASTVREAPRPLIHHP 121
S++P+ +T L TE+S+ P S P ST E PL P
Sbjct: 1004 STTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMP 1048
Score = 30.8 bits (68), Expect = 6.5
Identities = 15/48 (31%), Positives = 24/48 (50%)
Query: 77 SSSPLTGDTSLAVKTESSANPEKKLKKSKPASTVREAPRPLIHHPCMH 124
S++P+ T + TE++++P S P ST+ E PL P H
Sbjct: 1770 SATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSH 1817
Score = 30.4 bits (67), Expect = 8.5
Identities = 15/48 (31%), Positives = 24/48 (50%)
Query: 77 SSSPLTGDTSLAVKTESSANPEKKLKKSKPASTVREAPRPLIHHPCMH 124
S++P+ T + TE++++P S P ST+ E PL P H
Sbjct: 2241 SATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSH 2288
>gi|81295809 pericentrin [Homo sapiens]
Length = 3336
Score = 31.6 bits (70), Expect = 3.8
Identities = 17/44 (38%), Positives = 27/44 (61%), Gaps = 1/44 (2%)
Query: 187 QSFLRQQYDWSHIRDELTSASDLEL-LKQLEAEETAEFEDQSVI 229
Q F R++ DW +++EL ++ +L L LE E AE E Q++I
Sbjct: 743 QEFQRKETDWKVMKEELQREAEEKLTLMLLELREKAESEKQTII 786
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 31.6 bits (70), Expect = 3.8
Identities = 38/176 (21%), Positives = 80/176 (45%), Gaps = 20/176 (11%)
Query: 203 LTSASDLELLKQLEAEETAEFEDQSVILPPQEKKKPELLLP-VYYRLPSYFQQAETVEI- 260
LT+AS E+ ++ +E+A +I+P ++K++ +L L L QQ E+
Sbjct: 3184 LTTAS--EVFPEVVGDESA-----LLIVPEEDKQQQQLDLERELLELEKIKQQRFAEELE 3236
Query: 261 -----MPGNKSTEDIHEKTSLSQPQTQSY---FRQVTPRAGKFAYSTDNTFEQEIYFDEV 312
+ + E I + L + Q+ F+Q R +F + +Q++ +++
Sbjct: 3237 WERQEIQRFREQEKIMVQKKLEELQSMKQHLLFQQEEERQAQFMMRQETLAQQQLQLEQI 3296
Query: 313 QIIHQ-IGAKRDQIVLENLNRYNKQLSKVFPETPEKWSAQAIPEASYRPVQGALRW 367
Q + Q + + ++ + + +YN S +P+ + QAI E Y ++G+ W
Sbjct: 3297 QQLQQQLHQQLEEQKIRQIYQYNYDPSGT--ASPQTTTEQAILEGQYAALEGSQFW 3350
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 31.6 bits (70), Expect = 3.8
Identities = 38/176 (21%), Positives = 80/176 (45%), Gaps = 20/176 (11%)
Query: 203 LTSASDLELLKQLEAEETAEFEDQSVILPPQEKKKPELLLP-VYYRLPSYFQQAETVEI- 260
LT+AS E+ ++ +E+A +I+P ++K++ +L L L QQ E+
Sbjct: 3184 LTTAS--EVFPEVVGDESA-----LLIVPEEDKQQQQLDLERELLELEKIKQQRFAEELE 3236
Query: 261 -----MPGNKSTEDIHEKTSLSQPQTQSY---FRQVTPRAGKFAYSTDNTFEQEIYFDEV 312
+ + E I + L + Q+ F+Q R +F + +Q++ +++
Sbjct: 3237 WERQEIQRFREQEKIMVQKKLEELQSMKQHLLFQQEEERQAQFMMRQETLAQQQLQLEQI 3296
Query: 313 QIIHQ-IGAKRDQIVLENLNRYNKQLSKVFPETPEKWSAQAIPEASYRPVQGALRW 367
Q + Q + + ++ + + +YN S +P+ + QAI E Y ++G+ W
Sbjct: 3297 QQLQQQLHQQLEEQKIRQIYQYNYDPSGT--ASPQTTTEQAILEGQYAALEGSQFW 3350
>gi|239047795 pleckstrin homology domain containing, family A member
7 [Homo sapiens]
Length = 1121
Score = 31.2 bits (69), Expect = 5.0
Identities = 32/123 (26%), Positives = 51/123 (41%), Gaps = 17/123 (13%)
Query: 384 KDVPIKTRRLKKQAKSLQEDVTWELVVLRRMLKEWKTAWALIIEWHHETVENLLQSLGDL 443
+D P ++ Q K LQED+ L R E + AW ++ ++ VE L Q+L +
Sbjct: 737 RDQPQHLEKIAYQQKLLQEDLVHIRAELSRESTEMENAWNEYLKLEND-VEQLKQTLQEQ 795
Query: 444 H--------------DDVRIKAITTCATAALERPRIATS--QRDSDKTIQDLPEVLLPAL 487
H D RI+ +T +A E RI + KT+ P +P+L
Sbjct: 796 HRRAFFFQEKSQIQKDLWRIEDVTAGLSANKENFRILVESVKNPERKTVPLFPHPPVPSL 855
Query: 488 EAA 490
+
Sbjct: 856 STS 858
>gi|223278337 C-type lectin domain family 4, member M isoform 12
[Homo sapiens]
Length = 375
Score = 31.2 bits (69), Expect = 5.0
Identities = 32/146 (21%), Positives = 64/146 (43%), Gaps = 7/146 (4%)
Query: 274 TSLSQPQTQ--SYFRQVTPRAGKFAYSTDNTFEQEIYFDEVQIIHQIGAKRDQIVLENLN 331
+SLSQ Q++ + ++ +T ++ + QEIY + Q+ +G ++ L+ +
Sbjct: 76 SSLSQEQSEQDAIYQNLTQLKAAVGELSEKSKLQEIYQELTQLKAAVGELPEKSKLQEIY 135
Query: 332 RYNKQLSKVFPETPEKWSAQAIPEASYRPVQGALRWTALPTPAKDMLLQVGEKDVPIKTR 391
+ +L E PEK Q I + R L+ P K L ++ ++ +K
Sbjct: 136 QELTRLKAAVGELPEKSKLQEIYQELTR-----LKAAVGELPEKSKLQEIYQELTELKAA 190
Query: 392 RLKKQAKSLQEDVTWELVVLRRMLKE 417
+ KS +++ EL L+ + E
Sbjct: 191 VGELPEKSKLQEIYQELTQLKAAVGE 216
>gi|223278335 C-type lectin domain family 4, member M isoform 2
[Homo sapiens]
Length = 348
Score = 31.2 bits (69), Expect = 5.0
Identities = 32/146 (21%), Positives = 64/146 (43%), Gaps = 7/146 (4%)
Query: 274 TSLSQPQTQ--SYFRQVTPRAGKFAYSTDNTFEQEIYFDEVQIIHQIGAKRDQIVLENLN 331
+SLSQ Q++ + ++ +T ++ + QEIY + Q+ +G ++ L+ +
Sbjct: 49 SSLSQEQSEQDAIYQNLTQLKAAVGELSEKSKLQEIYQELTQLKAAVGELPEKSKLQEIY 108
Query: 332 RYNKQLSKVFPETPEKWSAQAIPEASYRPVQGALRWTALPTPAKDMLLQVGEKDVPIKTR 391
+ +L E PEK Q I + R L+ P K L ++ ++ +K
Sbjct: 109 QELTRLKAAVGELPEKSKLQEIYQELTR-----LKAAVGELPEKSKLQEIYQELTELKAA 163
Query: 392 RLKKQAKSLQEDVTWELVVLRRMLKE 417
+ KS +++ EL L+ + E
Sbjct: 164 VGELPEKSKLQEIYQELTQLKAAVGE 189
>gi|59891448 rapamycin-insensitive companion of mTOR [Homo sapiens]
Length = 1708
Score = 31.2 bits (69), Expect = 5.0
Identities = 26/101 (25%), Positives = 43/101 (42%), Gaps = 20/101 (19%)
Query: 631 KEVRRAAAQALGQMSLGKEV-HDIIRVKLG----------QGNSQERVEALYLIGELKLM 679
KEVR A +AL + + ++++K+ Q N ER +AL L+ ++ +
Sbjct: 97 KEVRAAGLRALRYLIQDSSILQKVLKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITV 156
Query: 680 TAKLLPSFLHCFSDDFTAVRRAACLAAGALQIRDKMVLECL 720
A L PS + + LQ RD+MV C+
Sbjct: 157 NASLFPS---------SVTNSLIAVGNDGLQERDRMVRACI 188
>gi|223278353 C-type lectin domain family 4, member M isoform 3
[Homo sapiens]
Length = 296
Score = 31.2 bits (69), Expect = 5.0
Identities = 38/181 (20%), Positives = 79/181 (43%), Gaps = 9/181 (4%)
Query: 274 TSLSQPQTQ--SYFRQVTPRAGKFAYSTDNTFEQEIYFDEVQIIHQIGAKRDQIVLENLN 331
+SLSQ Q++ + ++ +T ++ + QEIY + Q+ +G ++ L+ +
Sbjct: 49 SSLSQEQSEQDAIYQNLTQLKAAVGELSEKSKLQEIYQELTQLKAAVGELPEKSKLQEIY 108
Query: 332 RYNKQLSKVFPETPEKWSAQAIPEASYRPVQGALRWTALPTPAKDMLLQVGEKDVPIKTR 391
+ +L E PEK Q I + R L+ P K L ++ ++ +K
Sbjct: 109 QELTRLKAAVGELPEKSKLQEIYQELTR-----LKAAVGELPEKSKLQEIYQELTRLKAA 163
Query: 392 RLKKQAKSLQEDVTWELVVLRRMLKEWKTAWALIIEWHHETVENLLQSLGDLHDDVRIKA 451
+ KS +++ EL L+ + E L + ++ + L ++G+L D + +
Sbjct: 164 VGELPEKSKLQEIYQELTELKAAVGELPEKSKL--QEIYQELTQLKAAVGELPDQSKQQQ 221
Query: 452 I 452
I
Sbjct: 222 I 222
>gi|223278350 C-type lectin domain family 4, member M isoform 8
[Homo sapiens]
Length = 376
Score = 31.2 bits (69), Expect = 5.0
Identities = 32/146 (21%), Positives = 64/146 (43%), Gaps = 7/146 (4%)
Query: 274 TSLSQPQTQ--SYFRQVTPRAGKFAYSTDNTFEQEIYFDEVQIIHQIGAKRDQIVLENLN 331
+SLSQ Q++ + ++ +T ++ + QEIY + Q+ +G ++ L+ +
Sbjct: 77 SSLSQEQSEQDAIYQNLTQLKAAVGELSEKSKLQEIYQELTQLKAAVGELPEKSKLQEIY 136
Query: 332 RYNKQLSKVFPETPEKWSAQAIPEASYRPVQGALRWTALPTPAKDMLLQVGEKDVPIKTR 391
+ +L E PEK Q I + R L+ P K L ++ ++ +K
Sbjct: 137 QELTRLKAAVGELPEKSKLQEIYQELTR-----LKAAVGELPEKSKLQEIYQELTELKAA 191
Query: 392 RLKKQAKSLQEDVTWELVVLRRMLKE 417
+ KS +++ EL L+ + E
Sbjct: 192 VGELPEKSKLQEIYQELTQLKAAVGE 217
>gi|42542390 C-type lectin domain family 4, member M isoform 1 [Homo
sapiens]
Length = 399
Score = 31.2 bits (69), Expect = 5.0
Identities = 38/181 (20%), Positives = 79/181 (43%), Gaps = 9/181 (4%)
Query: 274 TSLSQPQTQ--SYFRQVTPRAGKFAYSTDNTFEQEIYFDEVQIIHQIGAKRDQIVLENLN 331
+SLSQ Q++ + ++ +T ++ + QEIY + Q+ +G ++ L+ +
Sbjct: 77 SSLSQEQSEQDAIYQNLTQLKAAVGELSEKSKLQEIYQELTQLKAAVGELPEKSKLQEIY 136
Query: 332 RYNKQLSKVFPETPEKWSAQAIPEASYRPVQGALRWTALPTPAKDMLLQVGEKDVPIKTR 391
+ +L E PEK Q I + R L+ P K L ++ ++ +K
Sbjct: 137 QELTRLKAAVGELPEKSKLQEIYQELTR-----LKAAVGELPEKSKLQEIYQELTRLKAA 191
Query: 392 RLKKQAKSLQEDVTWELVVLRRMLKEWKTAWALIIEWHHETVENLLQSLGDLHDDVRIKA 451
+ KS +++ EL L+ + E L + ++ + L ++G+L D + +
Sbjct: 192 VGELPEKSKLQEIYQELTELKAAVGELPEKSKL--QEIYQELTQLKAAVGELPDQSKQQQ 249
Query: 452 I 452
I
Sbjct: 250 I 250
>gi|224451124 neurobeachin-like 1 isoform 3 [Homo sapiens]
Length = 2694
Score = 31.2 bits (69), Expect = 5.0
Identities = 20/99 (20%), Positives = 43/99 (43%), Gaps = 5/99 (5%)
Query: 508 AIQSHNPLARNIMQTALLKGNSVDSWAAA--QCLALEGTATYPVIKRILHQLFTKKNEDT 565
A+Q+ +P ++ L DSW + + + T + ++H L + ++
Sbjct: 231 ALQAISPATMEVLMRVLA---DCDSWEDGDPEEVGRKAELTLKCLTEVVHILLSSNSDQR 287
Query: 566 EEQSYILLSYLSEKTTLIHTMLAVELNSCQWKNRIVACQ 604
+ ++ +L + H+ L + S QW+NR +A Q
Sbjct: 288 QVETSTILENYFKLLNSDHSALPNQRRSRQWENRFIALQ 326
>gi|67782311 superkiller viralicidic activity 2-like homolog [Homo
sapiens]
Length = 1246
Score = 31.2 bits (69), Expect = 5.0
Identities = 29/110 (26%), Positives = 47/110 (42%), Gaps = 10/110 (9%)
Query: 127 MLGRPPSLDVNLEEREAWLLPPEKEARAWEATVLEKLNERTARWIQSKRPRRPGASPNKW 186
+LG P D+ + P + ++ +LE N + +RP P AS + W
Sbjct: 93 VLGAPVPSDLQAQRH-----PTTGQILGYKEVLLENTNLSATTSLSLRRPPGP-ASQSLW 146
Query: 187 QSFLRQQYDWSHIRDELTSASDLELLKQLEAEETAEFEDQSVILPPQEKK 236
+ + + W DE T +L + EAEE +FE + +PP KK
Sbjct: 147 GNPTQYPF-WPGGMDEPTIT---DLNTREEAEEEIDFEKDLLTIPPGFKK 192
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.132 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,849,673
Number of Sequences: 37866
Number of extensions: 1739217
Number of successful extensions: 5538
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 38
Number of HSP's that attempted gapping in prelim test: 5438
Number of HSP's gapped (non-prelim): 140
length of query: 979
length of database: 18,247,518
effective HSP length: 112
effective length of query: 867
effective length of database: 14,006,526
effective search space: 12143658042
effective search space used: 12143658042
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.