Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 42544239
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|42544239 complement factor D preproprotein [Homo sapiens]
(253 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|42544239 complement factor D preproprotein [Homo sapiens] 521 e-148
gi|4885369 granzyme M precursor [Homo sapiens] 185 3e-47
gi|47551347 protease, serine-like 1 [Homo sapiens] 177 6e-45
gi|5453676 granzyme A precursor [Homo sapiens] 177 8e-45
gi|4504235 granzyme K precursor [Homo sapiens] 176 2e-44
gi|61744424 kallikrein-related peptidase 6 isoform A preproprote... 171 4e-43
gi|4506155 kallikrein-related peptidase 6 isoform A preproprotei... 171 4e-43
gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens] 170 1e-42
gi|21464127 kallikrein 8 isoform 2 [Homo sapiens] 169 2e-42
gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens] 160 8e-40
gi|4506145 protease, serine, 1 preproprotein [Homo sapiens] 160 1e-39
gi|4502907 chymase 1, mast cell preproprotein [Homo sapiens] 160 1e-39
gi|11496281 kallikrein 13 precursor [Homo sapiens] 159 2e-39
gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprot... 159 2e-39
gi|4502173 prostate specific antigen isoform 1 preproprotein [Ho... 157 8e-39
gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens] 155 2e-38
gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens] 155 2e-38
gi|4504875 kallikrein 1 preproprotein [Homo sapiens] 154 9e-38
gi|91823048 kallikrein 14 preproprotein [Homo sapiens] 154 9e-38
gi|221625528 granzyme B precursor [Homo sapiens] 153 1e-37
gi|4506153 prostasin preproprotein [Homo sapiens] 153 1e-37
gi|15529990 granzyme H [Homo sapiens] 153 2e-37
gi|4506147 protease, serine, 2 preproprotein [Homo sapiens] 151 6e-37
gi|58218970 protease, serine, 36 [Homo sapiens] 149 2e-36
gi|4503149 cathepsin G preproprotein [Homo sapiens] 149 3e-36
gi|22208987 kallikrein 12 isoform 2 [Homo sapiens] 148 5e-36
gi|117956391 protease, serine, 33 [Homo sapiens] 147 9e-36
gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 145 3e-35
gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens] 145 3e-35
gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 145 3e-35
>gi|42544239 complement factor D preproprotein [Homo sapiens]
Length = 253
Score = 521 bits (1342), Expect = e-148
Identities = 253/253 (100%), Positives = 253/253 (100%)
Query: 1 MHSWERLAVLVLLGAAACAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQW 60
MHSWERLAVLVLLGAAACAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQW
Sbjct: 1 MHSWERLAVLVLLGAAACAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQW 60
Query: 61 VLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQL 120
VLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQL
Sbjct: 61 VLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQL 120
Query: 121 SEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCN 180
SEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCN
Sbjct: 121 SEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCN 180
Query: 181 RRTHHDGAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTR 240
RRTHHDGAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTR
Sbjct: 181 RRTHHDGAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTR 240
Query: 241 VASYAAWIDSVLA 253
VASYAAWIDSVLA
Sbjct: 241 VASYAAWIDSVLA 253
>gi|4885369 granzyme M precursor [Homo sapiens]
Length = 257
Score = 185 bits (470), Expect = 3e-47
Identities = 103/248 (41%), Positives = 150/248 (60%), Gaps = 9/248 (3%)
Query: 9 VLVLLGAAACAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCL 68
+++ LGA + + +I+GGRE H+RPYMAS+Q NG+HLCGGVLV +WVL+AAHCL
Sbjct: 9 LVLALGALSVGSSFGTQIIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAHCL 68
Query: 69 EDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQP-DTIDHDLLLLQLSEKATLG 127
+++++LG H+L P + + + A+ HP +P +++DL LLQL K
Sbjct: 69 AQRM-AQLRLVLGLHTLDSPGLT---FHIKAAIQHPRYKPVPALENDLALLQLDGKVKPS 124
Query: 128 PAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDG 187
+RPL + VA GT C +AGWG+ + GR L+ + L VLD CN +G
Sbjct: 125 RTIRPLALPSKRQVVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWNG 184
Query: 188 AITERLMCAESNRRDS--CKGDSGGPLVC--GGVLEGVVTSGSRVCGNRKKPGIYTRVAS 243
+++ ++C ++ +D CKGDSGGPLVC G VL GV++ SRVC + KP + T VA
Sbjct: 185 SLSPSMVCLAADSKDQAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVATAVAP 244
Query: 244 YAAWIDSV 251
Y +WI V
Sbjct: 245 YVSWIRKV 252
>gi|47551347 protease, serine-like 1 [Homo sapiens]
Length = 283
Score = 177 bits (450), Expect = 6e-45
Identities = 103/261 (39%), Positives = 141/261 (54%), Gaps = 12/261 (4%)
Query: 1 MHSWERLAVLVLLGAAACAAPPRG----RILGGREAEAHARPYMASVQLNGAHLCGGVLV 56
+ W R + V PP G +I+GG E H+RPYMASV+ G H CGG L+
Sbjct: 5 LRGWGRPLLTVATALMLPVKPPAGSWGAQIIGGHEVTPHSRPYMASVRFGGQHHCGGFLL 64
Query: 57 AEQWVLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLL 116
+WV+SAAHC V+LGAH LS EP+++++ + HPD P T +D+
Sbjct: 65 RARWVVSAAHCFSHRDLRTGLVVLGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDIC 124
Query: 117 LLQLSEKATLGPAV--RPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVL 174
LL+L+ A LGPAV LP +R R GT C VAGWG V+ P L + VL
Sbjct: 125 LLRLNGSAVLGPAVGLLRLPGRRA-RPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVL 183
Query: 175 DRATCNRRTHHDGAITERLMC---AESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGN 231
D CN + G +T ++C +S+RR C DSGGPLVC G+V+ CG+
Sbjct: 184 DPDVCN--SSWKGHLTLTMLCTRSGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGD 241
Query: 232 RKKPGIYTRVASYAAWIDSVL 252
K P +YT+V+++ AWI V+
Sbjct: 242 PKTPDVYTQVSAFVAWIWDVV 262
>gi|5453676 granzyme A precursor [Homo sapiens]
Length = 262
Score = 177 bits (449), Expect = 8e-45
Identities = 95/230 (41%), Positives = 140/230 (60%), Gaps = 9/230 (3%)
Query: 25 RILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLLGAHS 84
+I+GG E H+RPYM + L+ +C G L+A+ WVL+AAHC + + QV+LGAHS
Sbjct: 28 KIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHC---NLNKRSQVILGAHS 84
Query: 85 LSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAP 144
+++ EP+K++ V + P+P P T + DL LLQL+EKA + V L + DV P
Sbjct: 85 ITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLTEKAKINKYVTILHLPKKGDDVKP 144
Query: 145 GTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHH--DGAITERLMCAESNR-- 200
GT+C VAGWG +++ D+L+ V + ++DR CN R H+ + I ++CA S R
Sbjct: 145 GTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGG 204
Query: 201 RDSCKGDSGGPLVCGGVLEGVVTSG-SRVCGNRKKPGIYTRVA-SYAAWI 248
RDSC GDSG PL+C GV GV + G CG+ + PG+Y ++ + WI
Sbjct: 205 RDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWI 254
>gi|4504235 granzyme K precursor [Homo sapiens]
Length = 264
Score = 176 bits (445), Expect = 2e-44
Identities = 100/234 (42%), Positives = 140/234 (59%), Gaps = 9/234 (3%)
Query: 26 ILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGK-VQVLLGAHS 84
I+GG+E H+RP+MAS+Q G H+CGGVL+ QWVL+AAHC G+ V+LGAHS
Sbjct: 27 IIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAHS 86
Query: 85 LSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAP 144
LS+ E SK+ ++ + +P D +D++L++L A L V+ L R +
Sbjct: 87 LSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKML-HIRSKTSLRS 145
Query: 145 GTLCDVAGWGIVNHAGRRP-DSLQHVLLPVLDRATCNRRTHHDG--AITERLMCA--ESN 199
GT C V GWG + RP D+L+ V + VL R CN +++++G IT+ ++CA
Sbjct: 146 GTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAGDAKG 205
Query: 200 RRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVA-SYAAWIDSVL 252
++DSCKGDSGGPL+C GV +V SG CG KPGIYT + Y WI S L
Sbjct: 206 QKDSCKGDSGGPLICKGVFHAIV-SGGHECGVATKPGIYTLLTKKYQTWIKSNL 258
>gi|61744424 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 171 bits (434), Expect = 4e-43
Identities = 96/247 (38%), Positives = 144/247 (58%), Gaps = 13/247 (5%)
Query: 9 VLVLLGAAACAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCL 68
++VL AA A + +++ G + + PY A++ +G LCGGVL+ WVL+AAHC
Sbjct: 5 MVVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCK 64
Query: 69 EDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGP 128
+ +QV LG H+L Q E S+ V+RAV HPD + D D++LL+L+ A L
Sbjct: 65 KP----NLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSE 120
Query: 129 AVRPLPWQRVDRDVAPGTL-CDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDG 187
++PLP ++RD + T C + GWG G PD++Q + ++ R C + G
Sbjct: 121 LIQPLP---LERDCSANTTSCHILGWGKTAD-GDFPDTIQCAYIHLVSREECEHA--YPG 174
Query: 188 AITERLMCA--ESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYA 245
IT+ ++CA E +DSC+GDSGGPLVCG L G+V+ G+ CG+++KPG+YT V Y
Sbjct: 175 QITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYT 234
Query: 246 AWIDSVL 252
WI +
Sbjct: 235 NWIQKTI 241
>gi|4506155 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 171 bits (434), Expect = 4e-43
Identities = 96/247 (38%), Positives = 144/247 (58%), Gaps = 13/247 (5%)
Query: 9 VLVLLGAAACAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCL 68
++VL AA A + +++ G + + PY A++ +G LCGGVL+ WVL+AAHC
Sbjct: 5 MVVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCK 64
Query: 69 EDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGP 128
+ +QV LG H+L Q E S+ V+RAV HPD + D D++LL+L+ A L
Sbjct: 65 KP----NLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSE 120
Query: 129 AVRPLPWQRVDRDVAPGTL-CDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDG 187
++PLP ++RD + T C + GWG G PD++Q + ++ R C + G
Sbjct: 121 LIQPLP---LERDCSANTTSCHILGWGKTAD-GDFPDTIQCAYIHLVSREECEHA--YPG 174
Query: 188 AITERLMCA--ESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYA 245
IT+ ++CA E +DSC+GDSGGPLVCG L G+V+ G+ CG+++KPG+YT V Y
Sbjct: 175 QITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYT 234
Query: 246 AWIDSVL 252
WI +
Sbjct: 235 NWIQKTI 241
>gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens]
Length = 260
Score = 170 bits (431), Expect = 1e-42
Identities = 95/250 (38%), Positives = 142/250 (56%), Gaps = 15/250 (6%)
Query: 10 LVLLGAAAC--AAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHC 67
L+LLG A + ++LGG E + H++P+ A++ LCGGVLV WVL+AAHC
Sbjct: 15 LLLLGGAWAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHC 74
Query: 68 LEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHP---DSQPDTIDHDLLLLQLSEKA 124
+ K V LG HSL + ++ V++++PHP S + +HDL+LLQL ++A
Sbjct: 75 KKP----KYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQA 130
Query: 125 TLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRR-PDSLQHVLLPVLDRATCNRRT 183
+LG V+P+ D PG C V+GWG V PD+L + + + C
Sbjct: 131 SLGSKVKPI--SLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDA- 187
Query: 184 HHDGAITERLMCAESNR-RDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVA 242
+ G IT+ ++CA S++ D+C+GDSGGPLVC G L+G+ + GS CG KPG+YT +
Sbjct: 188 -YPGQITDGMVCAGSSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNIC 246
Query: 243 SYAAWIDSVL 252
Y WI ++
Sbjct: 247 RYLDWIKKII 256
>gi|21464127 kallikrein 8 isoform 2 [Homo sapiens]
Length = 305
Score = 169 bits (429), Expect = 2e-42
Identities = 92/243 (37%), Positives = 138/243 (56%), Gaps = 13/243 (5%)
Query: 15 AAACAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADG 74
AA + ++LGG E + H++P+ A++ LCGGVLV WVL+AAHC +
Sbjct: 67 AAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKP---- 122
Query: 75 KVQVLLGAHSLSQPEPSKRLYDVLRAVPHP---DSQPDTIDHDLLLLQLSEKATLGPAVR 131
K V LG HSL + ++ V++++PHP S + +HDL+LLQL ++A+LG V+
Sbjct: 123 KYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVK 182
Query: 132 PLPWQRVDRDVAPGTLCDVAGWGIVNHAGRR-PDSLQHVLLPVLDRATCNRRTHHDGAIT 190
P+ D PG C V+GWG V PD+L + + + C + G IT
Sbjct: 183 PI--SLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDA--YPGQIT 238
Query: 191 ERLMCAESNR-RDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWID 249
+ ++CA S++ D+C+GDSGGPLVC G L+G+ + GS CG KPG+YT + Y WI
Sbjct: 239 DGMVCAGSSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIK 298
Query: 250 SVL 252
++
Sbjct: 299 KII 301
>gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens]
Length = 261
Score = 160 bits (406), Expect = 8e-40
Identities = 99/261 (37%), Positives = 142/261 (54%), Gaps = 22/261 (8%)
Query: 7 LAVLVLLGAAACAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAH 66
L++ + +G + RI+GG E E H++P+ +V +G CGGVLV QWVL+AAH
Sbjct: 6 LSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAH 65
Query: 67 CLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHP----------DSQPDT-IDHDL 115
CL+ + QV LG H+L +PE + + V + PHP +PD HDL
Sbjct: 66 CLKKNS----QVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDL 121
Query: 116 LLLQLSEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVN-HAGRRPDSLQHVLLPVL 174
+LL+LSE A + V+ L ++ A GT C +GWG + RP SLQ V L +L
Sbjct: 122 MLLRLSEPAKITDVVKVLGLPT--QEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLL 179
Query: 175 DRATCNRRTHHDGAITERLMCAE--SNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNR 232
C R + +TE ++CA + +D+C GDSGGPLVC GVL+G+ + G C
Sbjct: 180 SNDMCARA--YSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALP 237
Query: 233 KKPGIYTRVASYAAWIDSVLA 253
+KP +YT+V Y WI +A
Sbjct: 238 EKPAVYTKVVHYRKWIKDTIA 258
>gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]
Length = 247
Score = 160 bits (405), Expect = 1e-39
Identities = 91/244 (37%), Positives = 138/244 (56%), Gaps = 15/244 (6%)
Query: 15 AAACAAP--PRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAA 72
AAA AAP +I+GG E ++ PY S+ +G H CGG L+ EQWV+SA HC +
Sbjct: 11 AAALAAPFDDDDKIVGGYNCEENSVPYQVSLN-SGYHFCGGSLINEQWVVSAGHCYKS-- 67
Query: 73 DGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRP 132
++QV LG H++ E +++ + + + HP T+++D++L++LS +A + V
Sbjct: 68 --RIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVST 125
Query: 133 LPWQRVDRDVAPGTLCDVAGWGIVNHAGRR-PDSLQHVLLPVLDRATCNRRTHHDGAITE 191
+ A GT C ++GWG +G PD LQ + PVL +A C + G IT
Sbjct: 126 ISLPTAPP--ATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCE--ASYPGKITS 181
Query: 192 RLMCAE--SNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWID 249
+ C +DSC+GDSGGP+VC G L+GVV+ G C + KPG+YT+V +Y WI
Sbjct: 182 NMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDG-CAQKNKPGVYTKVYNYVKWIK 240
Query: 250 SVLA 253
+ +A
Sbjct: 241 NTIA 244
>gi|4502907 chymase 1, mast cell preproprotein [Homo sapiens]
Length = 247
Score = 160 bits (404), Expect = 1e-39
Identities = 93/252 (36%), Positives = 141/252 (55%), Gaps = 16/252 (6%)
Query: 7 LAVLVLLGAAACAAPPRGRILGGREAEAHARPYMASVQL---NG-AHLCGGVLVAEQWVL 62
L L LL C+ G I+GG E + H+RPYMA +++ NG + CGG L+ +VL
Sbjct: 3 LLPLPLLLFLLCSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVL 62
Query: 63 SAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSE 122
+AAHC A + V LGAH++++ E + + +V++ HP T+ HD++LL+L E
Sbjct: 63 TAAHC----AGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKE 118
Query: 123 KATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRR 182
KA+L AV LP+ V PG +C VAGWG D+LQ V L ++D C+
Sbjct: 119 KASLTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHF 178
Query: 183 THHDGAITERLMCAESNR--RDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTR 240
D + +C + R + + KGDSGGPL+C GV +G+V+ G + K P ++TR
Sbjct: 179 RDFDHNLQ---LCVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGR---SDAKPPAVFTR 232
Query: 241 VASYAAWIDSVL 252
++ Y WI+ +L
Sbjct: 233 ISHYRPWINQIL 244
>gi|11496281 kallikrein 13 precursor [Homo sapiens]
Length = 277
Score = 159 bits (403), Expect = 2e-39
Identities = 87/232 (37%), Positives = 134/232 (57%), Gaps = 14/232 (6%)
Query: 24 GRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLLGAH 83
G + GG H++P+ A++ + G LCGGVLV +WVL+AAHCL++ ++V LG H
Sbjct: 34 GFLPGGYTCFPHSQPWQAALLVQGRLLCGGVLVHPKWVLTAAHCLKEG----LKVYLGKH 89
Query: 84 SLSQPEPSKRLYDVLRAVPHPDSQPDTI----DHDLLLLQLSEKATLGPAVRPLPWQRVD 139
+L + E +++ +V+ ++PHP+ + DHD++LL+L L ++ LP +
Sbjct: 90 ALGRVEAGEQVREVVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLTGYIQTLPLSHNN 149
Query: 140 RDVAPGTLCDVAGWGIVNHAG-RRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMCAES 198
R + PGT C V+GWG P +LQ + + C R + G IT+ ++CA +
Sbjct: 150 R-LTPGTTCRVSGWGTTTSPQVNYPKTLQCANIQLRSDEEC--RQVYPGKITDNMLCAGT 206
Query: 199 NR--RDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWI 248
+DSC+GDSGGPLVC L G+V+ G CG +PG+YTRV+ Y WI
Sbjct: 207 KEGGKDSCEGDSGGPLVCNRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWI 258
>gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprotein
[Homo sapiens]
Length = 256
Score = 159 bits (402), Expect = 2e-39
Identities = 95/260 (36%), Positives = 144/260 (55%), Gaps = 27/260 (10%)
Query: 4 WERLAVLVLLGAAACAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLS 63
W L + LL A+ AA ++L G E H++P+ ++ G CG L++ WVLS
Sbjct: 2 WLLLTLSFLL--ASTAAQDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLS 59
Query: 64 AAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEK 123
AAHC ++V LG H+L + + ++L R +PHP + + +D++LL+L +
Sbjct: 60 AAHCQSRF----MRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQP 115
Query: 124 ATLGPAVRP--LPWQRVDRDVAPGTLCDVAGWGIVNH-----AGRR------PDSLQHVL 170
A L P VRP LP R PG C V+GWG+V+H AG PD+L
Sbjct: 116 ARLNPQVRPAVLP----TRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCAN 171
Query: 171 LPVLDRATCNRRTHHDGAITERLMCAESNRR--DSCKGDSGGPLVCGGVLEGVVTSGSRV 228
+ ++ +C++ + G +T ++CA + R +SC+GDSGGPLVCGG+L+G+V+ G
Sbjct: 172 ISIISDTSCDKS--YPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVP 229
Query: 229 CGNRKKPGIYTRVASYAAWI 248
C N KPG+YT+V Y WI
Sbjct: 230 CDNTTKPGVYTKVCHYLEWI 249
>gi|4502173 prostate specific antigen isoform 1 preproprotein [Homo
sapiens]
Length = 261
Score = 157 bits (397), Expect = 8e-39
Identities = 103/268 (38%), Positives = 143/268 (53%), Gaps = 28/268 (10%)
Query: 4 WERLAVLVLLGAAACAAPP-RGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVL 62
W + L L AAP RI+GG E E H++P+ V G +CGGVLV QWVL
Sbjct: 2 WVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVL 61
Query: 63 SAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQP-----------DTI 111
+AAHC+ + K +LLG HSL PE + +++ V + PHP D
Sbjct: 62 TAAHCIRN----KSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDS 117
Query: 112 DHDLLLLQLSEKATLGPAVR--PLPWQRVDRDVAPGTLCDVAGWGIVN-HAGRRPDSLQH 168
HDL+LL+LSE A L AV+ LP Q + A GT C +GWG + P LQ
Sbjct: 118 SHDLMLLRLSEPAELTDAVKVMDLPTQ----EPALGTTCYASGWGSIEPEEFLTPKKLQC 173
Query: 169 VLLPVLDRATCNRRTHHDGAITERLMCAE--SNRRDSCKGDSGGPLVCGGVLEGVVTSGS 226
V L V+ C + H +T+ ++CA + + +C GDSGGPLVC GVL+G+ + GS
Sbjct: 174 VDLHVISNDVCAQV--HPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGS 231
Query: 227 RVCGNRKKPGIYTRVASYAAWI-DSVLA 253
C ++P +YT+V Y WI D+++A
Sbjct: 232 EPCALPERPSLYTKVVHYRKWIKDTIVA 259
>gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens]
Length = 304
Score = 155 bits (393), Expect = 2e-38
Identities = 87/244 (35%), Positives = 137/244 (56%), Gaps = 13/244 (5%)
Query: 13 LGAAACAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAA 72
LG A +I+GG E ++ PY S+ +G+H CGG L++EQWV+SAAHC +
Sbjct: 68 LGTVAVPFDDDDKIVGGYTCEENSLPYQVSLN-SGSHFCGGSLISEQWVVSAAHCYKT-- 124
Query: 73 DGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRP 132
++QV LG H++ E +++ + + + HP DT+D+D++L++LS A + V
Sbjct: 125 --RIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVST 182
Query: 133 LPWQRVDRDVAPGTLCDVAGWG-IVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITE 191
+ A GT C ++GWG ++ PD L+ + PVL +A C + + G IT
Sbjct: 183 ISLPTA--PPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAEC--KASYPGKITN 238
Query: 192 RLMCAE--SNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWID 249
+ C +DSC+ DSGGP+VC G L+GVV+ G C + +PG+YT+V +Y WI
Sbjct: 239 SMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIK 297
Query: 250 SVLA 253
+A
Sbjct: 298 DTIA 301
>gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens]
Length = 247
Score = 155 bits (393), Expect = 2e-38
Identities = 89/249 (35%), Positives = 141/249 (56%), Gaps = 14/249 (5%)
Query: 9 VLVLLGAA-ACAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHC 67
+L +GAA A +I+GG E ++ PY S+ +G+H CGG L++EQWV+SAAHC
Sbjct: 6 ILAFVGAAVAVPFDDDDKIVGGYTCEENSLPYQVSLN-SGSHFCGGSLISEQWVVSAAHC 64
Query: 68 LEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLG 127
+ ++QV LG H++ E +++ + + + HP DT+D+D++L++LS A +
Sbjct: 65 YKT----RIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVIN 120
Query: 128 PAVRPLPWQRVDRDVAPGTLCDVAGWG-IVNHAGRRPDSLQHVLLPVLDRATCNRRTHHD 186
V + A GT C ++GWG ++ PD L+ + PVL +A C + +
Sbjct: 121 ARVSTISLPTA--PPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAEC--KASYP 176
Query: 187 GAITERLMCAE--SNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASY 244
G IT + C +DSC+ DSGGP+VC G L+GVV+ G C + +PG+YT+V +Y
Sbjct: 177 GKITNSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNY 235
Query: 245 AAWIDSVLA 253
WI +A
Sbjct: 236 VDWIKDTIA 244
>gi|4504875 kallikrein 1 preproprotein [Homo sapiens]
Length = 262
Score = 154 bits (388), Expect = 9e-38
Identities = 93/262 (35%), Positives = 137/262 (52%), Gaps = 23/262 (8%)
Query: 7 LAVLVLLGAAACAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAH 66
L + + LG A P + RI+GG E E H++P+ A++ CGG+LV QWVL+AAH
Sbjct: 6 LCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAH 65
Query: 67 CLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTID-----------HDL 115
C+ D Q+ LG H+L E + + V + PHP ++ HDL
Sbjct: 66 CISD----NYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDL 121
Query: 116 LLLQLSEKA-TLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRR-PDSLQHVLLPV 173
+LL+L+E A T+ AV+ + + +V G+ C +GWG + PD LQ V L +
Sbjct: 122 MLLRLTEPADTITDAVKVVELPTEEPEV--GSTCLASGWGSIEPENFSFPDDLQCVDLKI 179
Query: 174 LDRATCNRRTHHDGAITERLMCAE--SNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGN 231
L C + H +T+ ++C +D+C GDSGGPL+C GVL+GV + G CG
Sbjct: 180 LPNDECKKA--HVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGT 237
Query: 232 RKKPGIYTRVASYAAWIDSVLA 253
KP + RV SY WI+ +A
Sbjct: 238 PNKPSVAVRVLSYVKWIEDTIA 259
>gi|91823048 kallikrein 14 preproprotein [Homo sapiens]
Length = 267
Score = 154 bits (388), Expect = 9e-38
Identities = 91/250 (36%), Positives = 139/250 (55%), Gaps = 13/250 (5%)
Query: 8 AVLVLLGAAACAAPPRGRILGGREAEAHARPYMASVQLNGAH--LCGGVLVAEQWVLSAA 65
A+ VL A + +I+GG ++P+ A++ LCGG L++ QWV++AA
Sbjct: 23 ALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVITAA 82
Query: 66 HCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKAT 125
HC +QV LG H+L + E ++++ V+R V HP+ T D+DL+LLQL + A
Sbjct: 83 HCGRPI----LQVALGKHNLRRWEATQQVLRVVRQVTHPNYNSRTHDNDLMLLQLQQPAR 138
Query: 126 LGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHA-GRRPDSLQHVLLPVLDRATCNRRTH 184
+G AVRP+ + +PGT C V+GWG ++ R P SLQ V + + C +
Sbjct: 139 IGRAVRPI--EVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKA-- 194
Query: 185 HDGAITERLMCA--ESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVA 242
+ IT ++CA +DSC+GDSGGPLVC G L+G+V+ G C PG+YT +
Sbjct: 195 YPRTITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLC 254
Query: 243 SYAAWIDSVL 252
Y +WI+ +
Sbjct: 255 KYRSWIEETM 264
>gi|221625528 granzyme B precursor [Homo sapiens]
Length = 247
Score = 153 bits (387), Expect = 1e-37
Identities = 89/248 (35%), Positives = 127/248 (51%), Gaps = 11/248 (4%)
Query: 9 VLVLLGAAACAAPPRGRILGGREAEAHARPYMASVQL---NGAHLCGGVLVAEQWVLSAA 65
+L+LL G I+GG EA+ H+RPYMA + + CGG L+ + +VL+AA
Sbjct: 4 ILLLLAFLLLPRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAA 63
Query: 66 HCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKAT 125
HC + + V LGAH++ + EP+++ V R +PHP P +D++LLQL KA
Sbjct: 64 HCWGSS----INVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAK 119
Query: 126 LGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHH 185
AV+PL V PG C VAGWG G+ +LQ V + V + C H
Sbjct: 120 RTRAVQPLRLPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRH 179
Query: 186 DGAITERLMCAESN-RRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASY 244
T L + ++ S KGDSGGPLVC V +G+V+ G N P T+V+S+
Sbjct: 180 YYDSTIELCVGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYGR---NNGMPPRACTKVSSF 236
Query: 245 AAWIDSVL 252
WI +
Sbjct: 237 VHWIKKTM 244
>gi|4506153 prostasin preproprotein [Homo sapiens]
Length = 343
Score = 153 bits (387), Expect = 1e-37
Identities = 92/250 (36%), Positives = 127/250 (50%), Gaps = 16/250 (6%)
Query: 16 AACAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGK 75
A C P+ RI GG A A P+ S+ G H+CGG LV+EQWVLSAAHC +
Sbjct: 35 APCGVAPQARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKE 94
Query: 76 V-QVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLP 134
+V LGAH L ++ + +PHP + D+ LLQLS T +RP+
Sbjct: 95 AYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPIC 154
Query: 135 WQRVDRDVAPGTLCDVAGWGIV--NHAGRRPDSLQHVLLPVLDRATCNRRTHHDGA---- 188
+ G C V GWG V + + P LQ + +P++ R TCN + D
Sbjct: 155 LPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEP 214
Query: 189 --ITERLMCA--ESNRRDSCKGDSGGPLVCG----GVLEGVVTSGSRVCGNRKKPGIYTR 240
+ E ++CA +D+C+GDSGGPL C L G+V+ G CG R +PG+YT
Sbjct: 215 HFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGD-ACGARNRPGVYTL 273
Query: 241 VASYAAWIDS 250
+SYA+WI S
Sbjct: 274 ASSYASWIQS 283
>gi|15529990 granzyme H [Homo sapiens]
Length = 246
Score = 153 bits (386), Expect = 2e-37
Identities = 92/243 (37%), Positives = 126/243 (51%), Gaps = 12/243 (4%)
Query: 10 LVLLGAAACAAPPRGRILGGREAEAHARPYMASVQL---NGAHLCGGVLVAEQWVLSAAH 66
L+LL I+GG EA+ H+RPYMA VQ CGG+LV + +VL+AAH
Sbjct: 5 LLLLAFLLTPGAGTEEIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAH 64
Query: 67 CLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATL 126
C + V LGAH++ + E +++ V R +PHP P +D++LLQL KA
Sbjct: 65 C----QGSSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKW 120
Query: 127 GPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHD 186
AVRPL V PG LC VAGWG V+ +LQ VLL V C R H +
Sbjct: 121 TTAVRPLRLPSSKAQVKPGQLCSVAGWGYVS-MSTLATTLQEVLLTVQKDCQCERLFHGN 179
Query: 187 -GAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYA 245
TE + + KGDSGGPLVC V +G+++ G++ PG+Y +V+ +
Sbjct: 180 YSRATEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSYGNK---KGTPPGVYIKVSHFL 236
Query: 246 AWI 248
WI
Sbjct: 237 PWI 239
>gi|4506147 protease, serine, 2 preproprotein [Homo sapiens]
Length = 247
Score = 151 bits (381), Expect = 6e-37
Identities = 90/252 (35%), Positives = 139/252 (55%), Gaps = 15/252 (5%)
Query: 7 LAVLVLLGAAACAAP--PRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSA 64
L +++ AAA AAP +I+GG E ++ PY S+ +G H CGG L++EQWV+SA
Sbjct: 3 LLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLN-SGYHFCGGSLISEQWVVSA 61
Query: 65 AHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKA 124
HC + ++QV LG H++ E +++ + + + HP T+D+D+LL++LS A
Sbjct: 62 GHCYK----SRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPA 117
Query: 125 TLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGR-RPDSLQHVLLPVLDRATCNRRT 183
+ V + A GT ++GWG +G PD LQ + PVL +A C
Sbjct: 118 VINSRVSAISLPTA--PPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAEC--EA 173
Query: 184 HHDGAITERLMCAE--SNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRV 241
+ G IT + C +DSC+GDSGGP+V G L+G+V+ G C + +PG+YT+V
Sbjct: 174 SYPGKITNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGYG-CAQKNRPGVYTKV 232
Query: 242 ASYAAWIDSVLA 253
+Y WI +A
Sbjct: 233 YNYVDWIKDTIA 244
>gi|58218970 protease, serine, 36 [Homo sapiens]
Length = 855
Score = 149 bits (377), Expect = 2e-36
Identities = 100/251 (39%), Positives = 124/251 (49%), Gaps = 22/251 (8%)
Query: 18 CAAP-PRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHC------LED 70
C P P RI+GG A+ P+ S+ G H+CGG L+A WVLSAAHC LE
Sbjct: 38 CGRPEPSARIVGGSNAQPGTWPWQVSLHHGGGHICGGSLIAPSWVLSAAHCFMTNGTLEP 97
Query: 71 AADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAV 130
AA+ VLLG HS P V V + + DL LL+L+ A+LGPAV
Sbjct: 98 AAEW--SVLLGVHSQDGPLDGAHTRAVAAIVVPANYSQVELGADLALLRLASPASLGPAV 155
Query: 131 RPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDS--LQHVLLPVLDRATCNRRTHHDG- 187
P+ R GT C GWG V A P LQ V L +L ATC G
Sbjct: 156 WPVCLPRASHRFVHGTACWATGWGDVQEADPLPLPWVLQEVELRLLGEATCQCLYSQPGP 215
Query: 188 -----AITERLMCA--ESNRRDSCKGDSGGPLVC---GGVLEGVVTSGSRVCGNRKKPGI 237
I ++CA RRD+C+GDSGGPLVC G + +TS CG R +PG+
Sbjct: 216 FNLTLQILPGMLCAGYPEGRRDTCQGDSGGPLVCEEGGRWFQAGITSFGFGCGRRNRPGV 275
Query: 238 YTRVASYAAWI 248
+T VA+Y AWI
Sbjct: 276 FTAVATYEAWI 286
Score = 61.6 bits (148), Expect = 6e-10
Identities = 56/225 (24%), Positives = 91/225 (40%), Gaps = 29/225 (12%)
Query: 38 PYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVL------LGAHSLSQPEPS 91
P++A V + G +C G+L+A WVL+A HC+ V + GA SL Q
Sbjct: 602 PWLAEVHVAGDRVCTGILLAPGWVLAATHCVLRPGSTTVPYIEVYLGRAGASSLPQGHQV 661
Query: 92 KRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAPGTLCDVA 151
RL +R H +P L LL+LS + P+ P+ + PG C V
Sbjct: 662 SRLVISIRLPQHLGLRP-----PLALLELSSRVEPSPSALPICLH--PAGIPPGASCWVL 714
Query: 152 GWGIVNHAGRRPDSLQHV--LLPVLDRATCNRRTHHDGAITERLMCA--ESNRRDSCKGD 207
GW + P V + +L + C+ + G + +C + + C+
Sbjct: 715 GW-------KEPQDRVPVAAAVSILTQRICD--CLYQGILPPGTLCVLYAEGQENRCEMT 765
Query: 208 SGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVL 252
S PL+C + G V G+R+ ++ + AWI +
Sbjct: 766 SAPPLLCQMTEGSWILVGMAVQGSRE---LFAAIGPEEAWISQTV 807
Score = 58.2 bits (139), Expect = 7e-09
Identities = 43/128 (33%), Positives = 58/128 (45%), Gaps = 5/128 (3%)
Query: 29 GREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLED--AADGKVQVLLGAHSLS 86
G+ A P+ A V + G+ C G LV+E WVL+ A C D ++D + L L
Sbjct: 326 GKAPRPGAWPWEAQVMVPGSRPCHGALVSESWVLAPASCFLDPNSSDSPPRDLDAWRVLL 385
Query: 87 QPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAPGT 146
P R V R V H ++ D DL LLQL L A RP+ + PG+
Sbjct: 386 PSRP--RAERVARLVQHENASWDNAS-DLALLQLRTPVNLSAASRPVCLPHPEHYFLPGS 442
Query: 147 LCDVAGWG 154
C +A WG
Sbjct: 443 RCRLARWG 450
>gi|4503149 cathepsin G preproprotein [Homo sapiens]
Length = 255
Score = 149 bits (375), Expect = 3e-36
Identities = 93/250 (37%), Positives = 133/250 (53%), Gaps = 17/250 (6%)
Query: 9 VLVLLGAAACAAPPRGRILGGREAEAHARPYMASVQLN---GAHLCGGVLVAEQWVLSAA 65
+L+LL G I+GGRE+ H+RPYMA +Q+ G CGG LV E +VL+AA
Sbjct: 4 LLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAA 63
Query: 66 HCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKAT 125
HC + V LGAH++ + E +++ RA+ HP TI +D++LLQLS +
Sbjct: 64 HCW----GSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVR 119
Query: 126 LGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHH 185
V P+ R + PGTLC VAGWG V+ R D+L+ V L V C R
Sbjct: 120 RNRNVNPVALPRAQEGLRPGTLCTVAGWGRVS-MRRGTDTLREVQLRVQRDRQCLRIF-- 176
Query: 186 DGAITERLMCAESNRRD---SCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVA 242
G+ R +RR+ + KGDSGGPL+C V G+V+ G + P ++TRV+
Sbjct: 177 -GSYDPRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGK---SSGVPPEVFTRVS 232
Query: 243 SYAAWIDSVL 252
S+ WI + +
Sbjct: 233 SFLPWIRTTM 242
>gi|22208987 kallikrein 12 isoform 2 [Homo sapiens]
Length = 248
Score = 148 bits (373), Expect = 5e-36
Identities = 95/250 (38%), Positives = 141/250 (56%), Gaps = 18/250 (7%)
Query: 9 VLVLLGAAACAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCL 68
+L +LG + A P +I G E +++P+ + + CGGVL+ +WVL+AAHC
Sbjct: 8 LLCVLGLSQAATP---KIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAHC- 63
Query: 69 EDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPD--SQPDTIDHDLLLLQLSEKATL 126
+ + V LG HSLSQ + ++++ +V HP + +HDL LL+L +
Sbjct: 64 ---SGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRV 120
Query: 127 GPAVRPLPWQRVDRDVA-PGTLCDVAGWGIVNHAGRR-PDSLQHVLLPVLDRATCNRRTH 184
+V+PLP + D A GT C V+GWGI NH PD LQ + L ++ ATC+
Sbjct: 121 TSSVQPLP---LPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCH--GV 175
Query: 185 HDGAITERLMCAES-NRRDSCKGDSGGPLVCGGVLEGVVTSGS-RVCGNRKKPGIYTRVA 242
+ G IT ++CA +D+C+GDSGGPLVCGGVL+G+V+ GS CG PG+YT +
Sbjct: 176 YPGRITSNMVCAGGVPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYIC 235
Query: 243 SYAAWIDSVL 252
Y WI ++
Sbjct: 236 KYVDWIRMIM 245
>gi|117956391 protease, serine, 33 [Homo sapiens]
Length = 280
Score = 147 bits (371), Expect = 9e-36
Identities = 103/270 (38%), Positives = 137/270 (50%), Gaps = 26/270 (9%)
Query: 6 RLAVLVLLGAA--------ACAAPPRG-RILGGREAEAHARPYMASVQLNGAHLCGGVLV 56
++ +L++LGAA AC P RI+GGR+ P+ AS+Q GAH+CGG L+
Sbjct: 8 QVLLLLVLGAAGTQGRKSAACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAHVCGGSLI 67
Query: 57 AEQWVLSAAHCL-EDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDL 115
A QWVL+AAHC A + +V LGA L P V R + PD D DL
Sbjct: 68 APQWVLTAAHCFPRRALPAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARGDL 127
Query: 116 LLLQLSEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPD--SLQHVLLPV 173
LLQL L V+P+ PGT C V GWG + P+ LQ V +P+
Sbjct: 128 ALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVRVPL 187
Query: 174 LDRATCNRRTH--HDGAITERL-----MCA--ESNRRDSCKGDSGGPLVC----GGVLEG 220
LD TC+ H D ER+ +CA +D+C+GDSGGPL C VL G
Sbjct: 188 LDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVLVG 247
Query: 221 VVTSGSRVCGNRKKPGIYTRVASYAAWIDS 250
VV+ G + C +PG+YT VA+Y+ WI +
Sbjct: 248 VVSWG-KGCALPNRPGVYTSVATYSPWIQA 276
>gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 145 bits (366), Expect = 3e-35
Identities = 86/255 (33%), Positives = 140/255 (54%), Gaps = 17/255 (6%)
Query: 6 RLAVLVLLGAAACAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAA 65
R+ L+LL A RI+ G E + H++P+ A++ LCG L+A +W+L+AA
Sbjct: 2 RILQLILLALATGLVGGETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAA 61
Query: 66 HCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHP---DSQPDTIDH--DLLLLQL 120
HCL+ + V LG H+L + E ++ + PHP +S P+ DH D++L+++
Sbjct: 62 HCLKP----RYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNK-DHRNDIMLVKM 116
Query: 121 SEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRR-PDSLQHVLLPVLDRATC 179
+ ++ AVRPL R V GT C ++GWG + R P +L+ + +++ C
Sbjct: 117 ASPVSITWAVRPLTLS--SRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKC 174
Query: 180 NRRTHHDGAITERLMCA--ESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGI 237
+ G IT+ ++CA + +DSC+GDSGGPLVC L+G+++ G C +KPG+
Sbjct: 175 ENA--YPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGV 232
Query: 238 YTRVASYAAWIDSVL 252
YT+V Y WI +
Sbjct: 233 YTKVCKYVDWIQETM 247
>gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens]
Length = 282
Score = 145 bits (366), Expect = 3e-35
Identities = 86/255 (33%), Positives = 140/255 (54%), Gaps = 17/255 (6%)
Query: 6 RLAVLVLLGAAACAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAA 65
R+ L+LL A RI+ G E + H++P+ A++ LCG L+A +W+L+AA
Sbjct: 34 RILQLILLALATGLVGGETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAA 93
Query: 66 HCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHP---DSQPDTIDH--DLLLLQL 120
HCL+ + V LG H+L + E ++ + PHP +S P+ DH D++L+++
Sbjct: 94 HCLKP----RYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNK-DHRNDIMLVKM 148
Query: 121 SEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRR-PDSLQHVLLPVLDRATC 179
+ ++ AVRPL R V GT C ++GWG + R P +L+ + +++ C
Sbjct: 149 ASPVSITWAVRPLTLS--SRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKC 206
Query: 180 NRRTHHDGAITERLMCA--ESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGI 237
+ G IT+ ++CA + +DSC+GDSGGPLVC L+G+++ G C +KPG+
Sbjct: 207 ENA--YPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGV 264
Query: 238 YTRVASYAAWIDSVL 252
YT+V Y WI +
Sbjct: 265 YTKVCKYVDWIQETM 279
>gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 145 bits (366), Expect = 3e-35
Identities = 86/255 (33%), Positives = 140/255 (54%), Gaps = 17/255 (6%)
Query: 6 RLAVLVLLGAAACAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAA 65
R+ L+LL A RI+ G E + H++P+ A++ LCG L+A +W+L+AA
Sbjct: 2 RILQLILLALATGLVGGETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAA 61
Query: 66 HCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHP---DSQPDTIDH--DLLLLQL 120
HCL+ + V LG H+L + E ++ + PHP +S P+ DH D++L+++
Sbjct: 62 HCLKP----RYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNK-DHRNDIMLVKM 116
Query: 121 SEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRR-PDSLQHVLLPVLDRATC 179
+ ++ AVRPL R V GT C ++GWG + R P +L+ + +++ C
Sbjct: 117 ASPVSITWAVRPLTLS--SRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKC 174
Query: 180 NRRTHHDGAITERLMCA--ESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGI 237
+ G IT+ ++CA + +DSC+GDSGGPLVC L+G+++ G C +KPG+
Sbjct: 175 ENA--YPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGV 232
Query: 238 YTRVASYAAWIDSVL 252
YT+V Y WI +
Sbjct: 233 YTKVCKYVDWIQETM 247
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.431
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,192,106
Number of Sequences: 37866
Number of extensions: 532291
Number of successful extensions: 1831
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 169
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1160
Number of HSP's gapped (non-prelim): 199
length of query: 253
length of database: 18,247,518
effective HSP length: 100
effective length of query: 153
effective length of database: 14,460,918
effective search space: 2212520454
effective search space used: 2212520454
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.