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Search of human proteins with 41350305
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|41350305 neurexin 3 isoform 2 precursor [Homo sapiens]
(432 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|41350305 neurexin 3 isoform 2 precursor [Homo sapiens] 872 0.0
gi|157427673 neurexin 3 isoform 3 precursor [Homo sapiens] 845 0.0
gi|21070969 neurexin 3 isoform 1 precursor [Homo sapiens] 684 0.0
gi|21070967 neurexin 1 isoform beta precursor [Homo sapiens] 545 e-155
gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens] 488 e-138
gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens] 473 e-133
gi|21166382 neurexin 2 isoform beta precursor [Homo sapiens] 370 e-102
gi|21166380 neurexin 2 isoform alpha-2 precursor [Homo sapiens] 347 2e-95
gi|14211536 neurexin 2 isoform alpha-1 precursor [Homo sapiens] 331 9e-91
gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo sap... 50 3e-06
gi|4505463 contactin associated protein 1 precursor [Homo sapiens] 49 7e-06
gi|7662350 cell recognition molecule Caspr2 precursor [Homo sapi... 45 1e-04
gi|33469935 EGF-like, fibronectin type III and laminin G domains... 44 2e-04
gi|33469931 EGF-like, fibronectin type III and laminin G domains... 44 2e-04
gi|33469929 EGF-like, fibronectin type III and laminin G domains... 44 2e-04
gi|33469937 EGF-like, fibronectin type III and laminin G domains... 44 3e-04
gi|239743797 PREDICTED: similar to cell recognition molecule CAS... 43 5e-04
gi|239743754 PREDICTED: hypothetical protein LOC389722 isoform 1... 43 5e-04
gi|47519929 cell recognition molecule CASPR3 [Homo sapiens] 43 5e-04
gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 43 6e-04
gi|18640734 contactin associated protein-like 5 [Homo sapiens] 43 6e-04
gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 42 0.001
gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens] 42 0.001
gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 42 0.001
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 41 0.002
gi|148664242 cell recognition protein CASPR4 isoform 2 [Homo sap... 41 0.002
gi|239743756 PREDICTED: hypothetical protein LOC389722 isoform 2... 40 0.003
gi|54873613 agrin [Homo sapiens] 39 0.012
gi|4504229 glycophorin C isoform 1 [Homo sapiens] 38 0.020
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 37 0.027
>gi|41350305 neurexin 3 isoform 2 precursor [Homo sapiens]
Length = 432
Score = 872 bits (2254), Expect = 0.0
Identities = 432/432 (100%), Positives = 432/432 (100%)
Query: 1 MHLRIHARRSPPRRPAWTLGIWFLFWGCIVSSVWSSSNVASSSSTSSSPGSHSQHEHHFH 60
MHLRIHARRSPPRRPAWTLGIWFLFWGCIVSSVWSSSNVASSSSTSSSPGSHSQHEHHFH
Sbjct: 1 MHLRIHARRSPPRRPAWTLGIWFLFWGCIVSSVWSSSNVASSSSTSSSPGSHSQHEHHFH 60
Query: 61 GSKHHSVPISIYRSPVSLRGGHAGATYIFGKSGGLILYTWPANDRPSTRSDRLAVGFSTT 120
GSKHHSVPISIYRSPVSLRGGHAGATYIFGKSGGLILYTWPANDRPSTRSDRLAVGFSTT
Sbjct: 61 GSKHHSVPISIYRSPVSLRGGHAGATYIFGKSGGLILYTWPANDRPSTRSDRLAVGFSTT 120
Query: 121 VKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTR 180
VKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTR
Sbjct: 121 VKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTR 180
Query: 181 NGGNATLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGGKDKGRLFQGQLSGLYYDGLKVLN 240
NGGNATLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGGKDKGRLFQGQLSGLYYDGLKVLN
Sbjct: 181 NGGNATLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGGKDKGRLFQGQLSGLYYDGLKVLN 240
Query: 241 MAAENNPNIKINGSVRLVGEVPSILGTTQTTSMPPEMSTTVMETTTTMATTTTRKNRSTA 300
MAAENNPNIKINGSVRLVGEVPSILGTTQTTSMPPEMSTTVMETTTTMATTTTRKNRSTA
Sbjct: 241 MAAENNPNIKINGSVRLVGEVPSILGTTQTTSMPPEMSTTVMETTTTMATTTTRKNRSTA 300
Query: 301 SIQPTSDDLVSSAECSSDDEDFVECEPSTGRSANPTEPGIRRVPGASEVIRESSSTTGMV 360
SIQPTSDDLVSSAECSSDDEDFVECEPSTGRSANPTEPGIRRVPGASEVIRESSSTTGMV
Sbjct: 301 SIQPTSDDLVSSAECSSDDEDFVECEPSTGRSANPTEPGIRRVPGASEVIRESSSTTGMV 360
Query: 361 VGIVAAAALCILILLYAMYKYRNRDEGSYQVDETRNYISNSAQSNGTLMKEKQQSSKSGH 420
VGIVAAAALCILILLYAMYKYRNRDEGSYQVDETRNYISNSAQSNGTLMKEKQQSSKSGH
Sbjct: 361 VGIVAAAALCILILLYAMYKYRNRDEGSYQVDETRNYISNSAQSNGTLMKEKQQSSKSGH 420
Query: 421 KKQKNKDREYYV 432
KKQKNKDREYYV
Sbjct: 421 KKQKNKDREYYV 432
>gi|157427673 neurexin 3 isoform 3 precursor [Homo sapiens]
Length = 459
Score = 845 bits (2184), Expect = 0.0
Identities = 429/462 (92%), Positives = 429/462 (92%), Gaps = 33/462 (7%)
Query: 1 MHLRIHARRSPPRRPAWTLGIWFLFWGCIVSSVWSSSNVASSSSTSSSPGSHSQHEHHFH 60
MHLRIHARRSPPRRPAWTLGIWFLFWGCIVSSVWSSSNVASSSSTSSSPGSHSQHEHHFH
Sbjct: 1 MHLRIHARRSPPRRPAWTLGIWFLFWGCIVSSVWSSSNVASSSSTSSSPGSHSQHEHHFH 60
Query: 61 GSKHHSVPISIYRSPVSLRGGHAGATYIFGKSGGLILYTWPANDRPSTRSDRLAVGFSTT 120
GSKHHSVPISIYRSPVSLRGGHAGATYIFGKSGGLILYTWPANDRPSTRSDRLAVGFSTT
Sbjct: 61 GSKHHSVPISIYRSPVSLRGGHAGATYIFGKSGGLILYTWPANDRPSTRSDRLAVGFSTT 120
Query: 121 VKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTR 180
VKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTR
Sbjct: 121 VKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTR 180
Query: 181 NGGNATLQVDNWPVNEHYPT------------------------------GRQLTIFNTQ 210
NGGNATLQVDNWPVNEHYPT GRQLTIFNTQ
Sbjct: 181 NGGNATLQVDNWPVNEHYPTGNTDNERFQMVKQKIPFKYNRPVEEWLQEKGRQLTIFNTQ 240
Query: 211 AQIAIGGKDKGRLFQGQLSGLYYDGLKVLNMAAENNPNIKINGSVRLVGEVPSILGTTQT 270
AQIAIGGKDKGRLFQGQLSGLYYDGLKVLNMAAENNPNIKINGSVRLVGEVPSILGTTQT
Sbjct: 241 AQIAIGGKDKGRLFQGQLSGLYYDGLKVLNMAAENNPNIKINGSVRLVGEVPSILGTTQT 300
Query: 271 TSMPPEMSTTVMETTTTMATTTTRKNRSTASIQPTSDDLVSSAECSSDDEDFVECEPSTG 330
TSMPPEMSTTVMETTTTMATTTTRKNRSTASIQPTSDDLVSSAECSSDDEDFVECEPST
Sbjct: 301 TSMPPEMSTTVMETTTTMATTTTRKNRSTASIQPTSDDLVSSAECSSDDEDFVECEPST- 359
Query: 331 RSANPTEPGIRRVPGASEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQ 390
ANPTEPGIRRVPGASEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQ
Sbjct: 360 --ANPTEPGIRRVPGASEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQ 417
Query: 391 VDETRNYISNSAQSNGTLMKEKQQSSKSGHKKQKNKDREYYV 432
VDETRNYISNSAQSNGTLMKEKQQSSKSGHKKQKNKDREYYV
Sbjct: 418 VDETRNYISNSAQSNGTLMKEKQQSSKSGHKKQKNKDREYYV 459
>gi|21070969 neurexin 3 isoform 1 precursor [Homo sapiens]
Length = 1061
Score = 684 bits (1766), Expect = 0.0
Identities = 346/349 (99%), Positives = 346/349 (99%), Gaps = 3/349 (0%)
Query: 84 GATYIFGKSGGLILYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHI 143
GATYIFGKSGGLILYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHI
Sbjct: 716 GATYIFGKSGGLILYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHI 775
Query: 144 EQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGRQ 203
EQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGRQ
Sbjct: 776 EQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGRQ 835
Query: 204 LTIFNTQAQIAIGGKDKGRLFQGQLSGLYYDGLKVLNMAAENNPNIKINGSVRLVGEVPS 263
LTIFNTQAQIAIGGKDKGRLFQGQLSGLYYDGLKVLNMAAENNPNIKINGSVRLVGEVPS
Sbjct: 836 LTIFNTQAQIAIGGKDKGRLFQGQLSGLYYDGLKVLNMAAENNPNIKINGSVRLVGEVPS 895
Query: 264 ILGTTQTTSMPPEMSTTVMETTTTMATTTTRKNRSTASIQPTSDDLVSSAECSSDDEDFV 323
ILGTTQTTSMPPEMSTTVMETTTTMATTTTRKNRSTASIQPTSDDLVSSAECSSDDEDFV
Sbjct: 896 ILGTTQTTSMPPEMSTTVMETTTTMATTTTRKNRSTASIQPTSDDLVSSAECSSDDEDFV 955
Query: 324 ECEPSTGRSANPTEPGIRRVPGASEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRN 383
ECEPST ANPTEPGIRRVPGASEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRN
Sbjct: 956 ECEPST---ANPTEPGIRRVPGASEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRN 1012
Query: 384 RDEGSYQVDETRNYISNSAQSNGTLMKEKQQSSKSGHKKQKNKDREYYV 432
RDEGSYQVDETRNYISNSAQSNGTLMKEKQQSSKSGHKKQKNKDREYYV
Sbjct: 1013 RDEGSYQVDETRNYISNSAQSNGTLMKEKQQSSKSGHKKQKNKDREYYV 1061
Score = 39.7 bits (91), Expect = 0.005
Identities = 41/151 (27%), Positives = 66/151 (43%), Gaps = 19/151 (12%)
Query: 117 FSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIK-EERTPVNDGKYHV 175
F TT DG ++ +S G DF+ + + +G I VF++G IK P+ND ++H
Sbjct: 526 FKTTSPDGFIL-FNSGDG-NDFIAVELVKGYIHYVFDLGNGPNVIKGNSDRPLNDNQWHN 583
Query: 176 VRFTRNGGNA-TLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGGKDKGRLFQGQLSGLYYD 234
V TR+ N +L+VD V + + L + KG L+ L+ Y
Sbjct: 584 VVITRDNSNTHSLKVDTKVVTQVINGAKNLDL-------------KGDLYMAGLAQGMYS 630
Query: 235 GLKVLNMAAENNPNIKINGSVRLVGEVPSIL 265
L + A + SV L G +P ++
Sbjct: 631 NLP--KLVASRDGFQGCLASVDLNGRLPDLI 659
Score = 37.0 bits (84), Expect = 0.035
Identities = 23/92 (25%), Positives = 45/92 (48%), Gaps = 9/92 (9%)
Query: 108 TRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTP 167
T ++ ++ F + G+LV S D L+L ++ G++ ++ N+ + I+ + P
Sbjct: 331 TEAEDVSFRFMSQRAYGLLVATTSRDS-ADTLRLELDGGRVKLMVNLDCIRINCNSSKGP 389
Query: 168 --------VNDGKYHVVRFTRNGGNATLQVDN 191
+ND ++H VR R G + L VD+
Sbjct: 390 ETLYAGQKLNDNEWHTVRVVRRGKSLKLTVDD 421
Score = 35.0 bits (79), Expect = 0.13
Identities = 18/86 (20%), Positives = 43/86 (50%), Gaps = 2/86 (2%)
Query: 137 DFLQLHIEQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTRNGGNATLQVDNWPVNE 196
DF + + G + ++ ++G+ I +K + NDG+++ V R+G + T+ V++
Sbjct: 133 DFFAVELLDGNLYLLLDMGSGTIKVKATQKKANDGEWYHVDIQRDGRSGTISVNS--RRT 190
Query: 197 HYPTGRQLTIFNTQAQIAIGGKDKGR 222
+ + I + + + +GG + R
Sbjct: 191 PFTASGESEILDLEGDMYLGGLPENR 216
>gi|21070967 neurexin 1 isoform beta precursor [Homo sapiens]
Length = 442
Score = 545 bits (1403), Expect = e-155
Identities = 281/394 (71%), Positives = 323/394 (81%), Gaps = 9/394 (2%)
Query: 46 SSSPGSHSQHEHHFHGS-KHHSVPISIYRSPVSLRGGHAGATYIFGKSGGLILYTWPAND 104
+SS G+H H HHFHGS KHHSVPI+IYRSP SLRGGHAG TYIF K GG I Y WP ND
Sbjct: 51 ASSLGAH--HIHHFHGSSKHHSVPIAIYRSPASLRGGHAGTTYIFSKGGGQITYKWPPND 108
Query: 105 RPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEE 164
RPSTR+DRLA+GFST K+ +LVR+DS+ GLGD+L+LHI QGKIGV FN+GT DI+I+E
Sbjct: 109 RPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEES 168
Query: 165 RTPVNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGGKDKGRLF 224
+NDGKYHVVRFTR+GGNATLQVD+WPV E YP GRQLTIFN+QA I IGGK++G+ F
Sbjct: 169 NAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGRQLTIFNSQATIIIGGKEQGQPF 228
Query: 225 QGQLSGLYYDGLKVLNMAAENNPNIKINGSVRLVGEVPSILGTTQT-TSMPPEMSTTVME 283
QGQLSGLYY+GLKVLNMAAEN+ NI I G+VRLVGEVPS + T T T+M EMST++ME
Sbjct: 229 QGQLSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPSSMTTESTATAMQSEMSTSIME 288
Query: 284 TTTTMATTTTRKNRSTAS---IQPTSDDLVSSAECSSDDEDFVECEPSTGRSANPTEPGI 340
TTTT+AT+T R+ + Q T D LV+SAEC SDDED CEPS+G ANPT G
Sbjct: 289 TTTTLATSTARRGKPPTKEPISQTTDDILVASAECPSDDEDIDPCEPSSGGLANPTRAGG 348
Query: 341 RR-VPGASEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQVDETRNYIS 399
R PG++EVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSY VDE+RNYIS
Sbjct: 349 REPYPGSAEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYIS 408
Query: 400 NSAQSNGTLMKEKQQSS-KSGHKKQKNKDREYYV 432
NSAQSNG ++KEKQ SS KS +K +KNKD+EYYV
Sbjct: 409 NSAQSNGAVVKEKQPSSAKSSNKNKKNKDKEYYV 442
>gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens]
Length = 1477
Score = 488 bits (1257), Expect = e-138
Identities = 251/355 (70%), Positives = 290/355 (81%), Gaps = 6/355 (1%)
Query: 84 GATYIFGKSGGLILYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHI 143
G TYIF K GG I Y WP NDRPSTR+DRLA+GFST K+ +LVR+DS+ GLGD+L+LHI
Sbjct: 1123 GTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHI 1182
Query: 144 EQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGRQ 203
QGKIGV FN+GT DI+I+E +NDGKYHVVRFTR+GGNATLQVD+WPV E YP GRQ
Sbjct: 1183 HQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGRQ 1242
Query: 204 LTIFNTQAQIAIGGKDKGRLFQGQLSGLYYDGLKVLNMAAENNPNIKINGSVRLVGEVPS 263
LTIFN+QA I IGGK++G+ FQGQLSGLYY+GLKVLNMAAEN+ NI I G+VRLVGEVPS
Sbjct: 1243 LTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPS 1302
Query: 264 ILGTTQT-TSMPPEMSTTVMETTTTMATTTTRKNRSTAS---IQPTSDDLVSSAECSSDD 319
+ T T T+M EMST++METTTT+AT+T R+ + Q T D LV+SAEC SDD
Sbjct: 1303 SMTTESTATAMQSEMSTSIMETTTTLATSTARRGKPPTKEPISQTTDDILVASAECPSDD 1362
Query: 320 EDFVECEPSTGRSANPTEPGIRR-VPGASEVIRESSSTTGMVVGIVAAAALCILILLYAM 378
ED CEPS+G ANPT G R PG++EVIRESSSTTGMVVGIVAAAALCILILLYAM
Sbjct: 1363 EDIDPCEPSSGGLANPTRAGGREPYPGSAEVIRESSSTTGMVVGIVAAAALCILILLYAM 1422
Query: 379 YKYRNRDEGSYQVDETRNYISNSAQSNGTLMKEKQQSS-KSGHKKQKNKDREYYV 432
YKYRNRDEGSY VDE+RNYISNSAQSNG ++KEKQ SS KS +K +KNKD+EYYV
Sbjct: 1423 YKYRNRDEGSYHVDESRNYISNSAQSNGAVVKEKQPSSAKSSNKNKKNKDKEYYV 1477
Score = 38.9 bits (89), Expect = 0.009
Identities = 28/88 (31%), Positives = 45/88 (51%), Gaps = 4/88 (4%)
Query: 124 GILVRIDSAPGLGDFLQLHIEQG-KIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTRNG 182
G+++ D G DFL+L + +G ++ + F+I + + TPVNDG +H VR R
Sbjct: 65 GLVLYFDDE-GFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVNDGAWHSVRIRRQF 123
Query: 183 GNATLQVDNWPVN--EHYPTGRQLTIFN 208
N TL +D E R +T+F+
Sbjct: 124 RNTTLFIDQVEAKWVEVKSKRRDMTVFS 151
Score = 37.7 bits (86), Expect = 0.020
Identities = 43/206 (20%), Positives = 86/206 (41%), Gaps = 35/206 (16%)
Query: 25 FWGCIVSSVWSSSNVASSSSTSSSPGSHSQHEHHFHGSKHHSV----PISIYRSPVSL-- 78
F GC+ V+ +++V S + G H K +V PI+ + +P S
Sbjct: 434 FMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPIT-FETPESFIS 492
Query: 79 -------RGGHAGATYIFGKSGGLILYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDS 131
+ G + + GLIL++ + +P + D K ++++D
Sbjct: 493 LPKWNAKKTGSISFDFRTTEPNGLILFS---HGKPRHQKD---------AKHPQMIKVD- 539
Query: 132 APGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTRNGGNATLQVDN 191
F + + G + ++ ++G+ I IK VNDG+++ V F R+G + T+ V+
Sbjct: 540 ------FFAIEMLDGHLYLLLDMGSGTIKIKALLKKVNDGEWYHVDFQRDGRSGTISVNT 593
Query: 192 WPVNEHYPTGRQLTIFNTQAQIAIGG 217
+ Y + I + ++ +GG
Sbjct: 594 --LRTPYTAPGESEILDLDDELYLGG 617
Score = 37.4 bits (85), Expect = 0.027
Identities = 23/92 (25%), Positives = 45/92 (48%), Gaps = 9/92 (9%)
Query: 108 TRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTP 167
T ++ +++ F + GIL+ S D L+L ++ G++ + N+ + I+ + P
Sbjct: 737 TEAEDVSLRFRSQRAYGILMATTSRDS-ADTLRLELDAGRVKLTVNLDCIRINCNSSKGP 795
Query: 168 --------VNDGKYHVVRFTRNGGNATLQVDN 191
+ND ++H VR R G + L VD+
Sbjct: 796 ETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDD 827
Score = 37.0 bits (84), Expect = 0.035
Identities = 30/106 (28%), Positives = 54/106 (50%), Gaps = 7/106 (6%)
Query: 117 FSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIK-EERTPVNDGKYHV 175
F TT DG+++ +S G DF+ + + +G + VF++G IK P+ND ++H
Sbjct: 933 FKTTSLDGLIL-YNSGDG-NDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLNDNQWHN 990
Query: 176 VRFTRNGGNA-TLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGGKDK 220
V +R+ N T+++D + R L + ++ + IGG K
Sbjct: 991 VMISRDTSNLHTVKIDTKITTQITAGARNLDL---KSDLYIGGVAK 1033
>gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens]
Length = 1547
Score = 473 bits (1216), Expect = e-133
Identities = 251/385 (65%), Positives = 290/385 (75%), Gaps = 36/385 (9%)
Query: 84 GATYIFGKSGGLILYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHI 143
G TYIF K GG I Y WP NDRPSTR+DRLA+GFST K+ +LVR+DS+ GLGD+L+LHI
Sbjct: 1163 GTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHI 1222
Query: 144 EQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPT--- 200
QGKIGV FN+GT DI+I+E +NDGKYHVVRFTR+GGNATLQVD+WPV E YP
Sbjct: 1223 HQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGNN 1282
Query: 201 ---------------------------GRQLTIFNTQAQIAIGGKDKGRLFQGQLSGLYY 233
GRQLTIFN+QA I IGGK++G+ FQGQLSGLYY
Sbjct: 1283 DNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQATIIIGGKEQGQPFQGQLSGLYY 1342
Query: 234 DGLKVLNMAAENNPNIKINGSVRLVGEVPSILGTTQT-TSMPPEMSTTVMETTTTMATTT 292
+GLKVLNMAAEN+ NI I G+VRLVGEVPS + T T T+M EMST++METTTT+AT+T
Sbjct: 1343 NGLKVLNMAAENDANIAIVGNVRLVGEVPSSMTTESTATAMQSEMSTSIMETTTTLATST 1402
Query: 293 TRKNRSTAS---IQPTSDDLVSSAECSSDDEDFVECEPSTGRSANPTEPGIRR-VPGASE 348
R+ + Q T D LV+SAEC SDDED CEPS+G ANPT G R PG++E
Sbjct: 1403 ARRGKPPTKEPISQTTDDILVASAECPSDDEDIDPCEPSSGGLANPTRAGGREPYPGSAE 1462
Query: 349 VIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQVDETRNYISNSAQSNGTL 408
VIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSY VDE+RNYISNSAQSNG +
Sbjct: 1463 VIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNSAQSNGAV 1522
Query: 409 MKEKQQSS-KSGHKKQKNKDREYYV 432
+KEKQ SS KS +K +KNKD+EYYV
Sbjct: 1523 VKEKQPSSAKSSNKNKKNKDKEYYV 1547
Score = 38.9 bits (89), Expect = 0.009
Identities = 28/88 (31%), Positives = 45/88 (51%), Gaps = 4/88 (4%)
Query: 124 GILVRIDSAPGLGDFLQLHIEQG-KIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTRNG 182
G+++ D G DFL+L + +G ++ + F+I + + TPVNDG +H VR R
Sbjct: 65 GLVLYFDDE-GFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVNDGAWHSVRIRRQF 123
Query: 183 GNATLQVDNWPVN--EHYPTGRQLTIFN 208
N TL +D E R +T+F+
Sbjct: 124 RNTTLFIDQVEAKWVEVKSKRRDMTVFS 151
Score = 37.7 bits (86), Expect = 0.020
Identities = 43/206 (20%), Positives = 86/206 (41%), Gaps = 35/206 (16%)
Query: 25 FWGCIVSSVWSSSNVASSSSTSSSPGSHSQHEHHFHGSKHHSV----PISIYRSPVSL-- 78
F GC+ V+ +++V S + G H K +V PI+ + +P S
Sbjct: 474 FMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPIT-FETPESFIS 532
Query: 79 -------RGGHAGATYIFGKSGGLILYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDS 131
+ G + + GLIL++ + +P + D K ++++D
Sbjct: 533 LPKWNAKKTGSISFDFRTTEPNGLILFS---HGKPRHQKD---------AKHPQMIKVD- 579
Query: 132 APGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTRNGGNATLQVDN 191
F + + G + ++ ++G+ I IK VNDG+++ V F R+G + T+ V+
Sbjct: 580 ------FFAIEMLDGHLYLLLDMGSGTIKIKALLKKVNDGEWYHVDFQRDGRSGTISVNT 633
Query: 192 WPVNEHYPTGRQLTIFNTQAQIAIGG 217
+ Y + I + ++ +GG
Sbjct: 634 --LRTPYTAPGESEILDLDDELYLGG 657
Score = 37.4 bits (85), Expect = 0.027
Identities = 23/92 (25%), Positives = 45/92 (48%), Gaps = 9/92 (9%)
Query: 108 TRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTP 167
T ++ +++ F + GIL+ S D L+L ++ G++ + N+ + I+ + P
Sbjct: 777 TEAEDVSLRFRSQRAYGILMATTSRDS-ADTLRLELDAGRVKLTVNLDCIRINCNSSKGP 835
Query: 168 --------VNDGKYHVVRFTRNGGNATLQVDN 191
+ND ++H VR R G + L VD+
Sbjct: 836 ETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDD 867
Score = 37.0 bits (84), Expect = 0.035
Identities = 30/106 (28%), Positives = 54/106 (50%), Gaps = 7/106 (6%)
Query: 117 FSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIK-EERTPVNDGKYHV 175
F TT DG+++ +S G DF+ + + +G + VF++G IK P+ND ++H
Sbjct: 973 FKTTSLDGLIL-YNSGDG-NDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLNDNQWHN 1030
Query: 176 VRFTRNGGNA-TLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGGKDK 220
V +R+ N T+++D + R L + ++ + IGG K
Sbjct: 1031 VMISRDTSNLHTVKIDTKITTQITAGARNLDL---KSDLYIGGVAK 1073
>gi|21166382 neurexin 2 isoform beta precursor [Homo sapiens]
Length = 666
Score = 370 bits (951), Expect = e-102
Identities = 194/327 (59%), Positives = 234/327 (71%), Gaps = 37/327 (11%)
Query: 40 ASSSSTSSSPGSHSQHEHHFHGSKHHSVPISIYRSPVSLRGGHAGATYIFGKSGGLILYT 99
A+ + SS S + H HHFH SKH +VPI+I R P RGGHAG TYIFGK G LI YT
Sbjct: 47 AAEGARVSSSLSTTHHVHHFH-SKHGTVPIAINRMPFLTRGGHAGTTYIFGKGGALITYT 105
Query: 100 WPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDI 159
WP NDRPSTR DRLAVGFST + +LVR+DSA GLGD+LQLHI+QG +GV+FN+GT DI
Sbjct: 106 WPPNDRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHIDQGTVGVIFNVGTDDI 165
Query: 160 SIKEERTPVNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPT------------------- 200
+I E V+DGKYHVVRFTR+GGNATLQVD+WPVNE YP
Sbjct: 166 TIDEPNAIVSDGKYHVVRFTRSGGNATLQVDSWPVNERYPAGNFDNERLAIARQRIPYRL 225
Query: 201 -----------GRQLTIFNTQAQIAIGGKDKGRLFQGQLSGLYYDGLKVLNMAAENNPNI 249
GRQLTIFN+QA I IGG+D+GR FQGQ+SGLYY+GLKVL +AAE++PN+
Sbjct: 226 GRVVDEWLLDKGRQLTIFNSQAAIKIGGRDQGRPFQGQVSGLYYNGLKVLALAAESDPNV 285
Query: 250 KINGSVRLVGEVPSILGTTQT--TSMPPEMSTTVMETTTTMATTTTRKNRS----TASIQ 303
+ G +RLVGE PS+L + +T T++ +M+TT+METTTTMATTTTR+ RS ++ Q
Sbjct: 286 RTEGHLRLVGEGPSVLLSAETTATTLLADMATTIMETTTTMATTTTRRGRSPTLRDSTTQ 345
Query: 304 PTSDDLVSSAECSSDDEDFVECEPSTG 330
T D LV+SAEC SDDED ECEPSTG
Sbjct: 346 NTDDLLVASAECPSDDEDLEECEPSTG 372
Score = 155 bits (392), Expect = 7e-38
Identities = 80/102 (78%), Positives = 90/102 (88%), Gaps = 1/102 (0%)
Query: 332 SANPTEPGIRRVPGASEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQV 391
+ANPT PG R PGA EVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQV
Sbjct: 565 TANPTGPGERGPPGAVEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQV 624
Query: 392 DETRNYISNSAQSNGTLMKEKQQSS-KSGHKKQKNKDREYYV 432
D++RNYISNSAQSNG ++KEK ++ K+ K +KNKD+EYYV
Sbjct: 625 DQSRNYISNSAQSNGAVVKEKAPAAPKTPSKAKKNKDKEYYV 666
>gi|21166380 neurexin 2 isoform alpha-2 precursor [Homo sapiens]
Length = 1642
Score = 347 bits (889), Expect = 2e-95
Identities = 171/253 (67%), Positives = 206/253 (81%), Gaps = 6/253 (2%)
Query: 84 GATYIFGKSGGLILYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHI 143
G TYIFGK G LI YTWP NDRPSTR DRLAVGFST + +LVR+DSA GLGD+LQLHI
Sbjct: 1096 GTTYIFGKGGALITYTWPPNDRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHI 1155
Query: 144 EQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGRQ 203
+QG +GV+FN+GT DI+I E V+DGKYHVVRFTR+GGNATLQVD+WPVNE YP GRQ
Sbjct: 1156 DQGTVGVIFNVGTDDITIDEPNAIVSDGKYHVVRFTRSGGNATLQVDSWPVNERYPAGRQ 1215
Query: 204 LTIFNTQAQIAIGGKDKGRLFQGQLSGLYYDGLKVLNMAAENNPNIKINGSVRLVGEVPS 263
LTIFN+QA I IGG+D+GR FQGQ+SGLYY+GLKVL +AAE++PN++ G +RLVGE PS
Sbjct: 1216 LTIFNSQAAIKIGGRDQGRPFQGQVSGLYYNGLKVLALAAESDPNVRTEGHLRLVGEGPS 1275
Query: 264 ILGTTQT--TSMPPEMSTTVMETTTTMATTTTRKNRS----TASIQPTSDDLVSSAECSS 317
+L + +T T++ +M+TT+METTTTMATTTTR+ RS ++ Q T D LV+SAEC S
Sbjct: 1276 VLLSAETTATTLLADMATTIMETTTTMATTTTRRGRSPTLRDSTTQNTDDLLVASAECPS 1335
Query: 318 DDEDFVECEPSTG 330
DDED ECEPSTG
Sbjct: 1336 DDEDLEECEPSTG 1348
Score = 155 bits (392), Expect = 7e-38
Identities = 80/102 (78%), Positives = 90/102 (88%), Gaps = 1/102 (0%)
Query: 332 SANPTEPGIRRVPGASEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQV 391
+ANPT PG R PGA EVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQV
Sbjct: 1541 TANPTGPGERGPPGAVEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQV 1600
Query: 392 DETRNYISNSAQSNGTLMKEKQQSS-KSGHKKQKNKDREYYV 432
D++RNYISNSAQSNG ++KEK ++ K+ K +KNKD+EYYV
Sbjct: 1601 DQSRNYISNSAQSNGAVVKEKAPAAPKTPSKAKKNKDKEYYV 1642
Score = 50.4 bits (119), Expect = 3e-06
Identities = 36/106 (33%), Positives = 58/106 (54%), Gaps = 7/106 (6%)
Query: 117 FSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIK-EERTPVNDGKYHV 175
F TT DG+L+ +S G DF+ + + +G I VF++G +K PVND ++H
Sbjct: 906 FKTTAPDGLLL-FNSGNG-NDFIVIELVKGYIHYVFDLGNGPSLMKGNSDKPVNDNQWHN 963
Query: 176 VRFTRNGGNA-TLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGGKDK 220
V +R+ GN TL++D+ V +H R L + + ++ IGG K
Sbjct: 964 VVVSRDPGNVHTLKIDSRTVTQHSNGARNLDL---KGELYIGGLSK 1006
Score = 41.6 bits (96), Expect = 0.001
Identities = 37/169 (21%), Positives = 69/169 (40%), Gaps = 27/169 (15%)
Query: 110 SDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGT--VDISIKEERTP 167
+D + + F T ++G+++ + D++ L ++ G + +V N+G+ + ++
Sbjct: 287 TDEITLAFRTLQRNGLMLHTGKS---ADYVNLSLKSGAVWLVINLGSGAFEALVEPVNGK 343
Query: 168 VNDGKYHVVRFTRN--------GGNATLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGGKD 219
ND +H VR TRN T+ VD Y T T+ + IGG
Sbjct: 344 FNDNAWHDVRVTRNLRQHAGIGHAMVTISVDGILTTTGY-TQEDYTMLGSDDFFYIGGSP 402
Query: 220 K---------GRLFQGQLSGLYYDG----LKVLNMAAENNPNIKINGSV 255
F G L + Y L++ +A E +P +K+ G +
Sbjct: 403 NTADLPGSPVSNNFMGCLKDVVYKNNDFKLELSRLAKEGDPKMKLQGDL 451
Score = 39.3 bits (90), Expect = 0.007
Identities = 23/81 (28%), Positives = 40/81 (49%), Gaps = 1/81 (1%)
Query: 110 SDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTPVN 169
S L+ T +L+ +D G DFL+L + G++ + F + + + + TPV
Sbjct: 50 SGELSFSLRTNATRALLLYLDDG-GDCDFLELLLVDGRLRLRFTLSCAEPATLQLDTPVA 108
Query: 170 DGKYHVVRFTRNGGNATLQVD 190
D ++H+V TR+ L VD
Sbjct: 109 DDRWHMVLLTRDARRTALAVD 129
Score = 35.4 bits (80), Expect = 0.10
Identities = 33/146 (22%), Positives = 63/146 (43%), Gaps = 12/146 (8%)
Query: 108 TRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTP 167
T ++ +++ F + G+++ S D L+L ++ G++ + N+G ++
Sbjct: 720 TEAEDVSLRFMSQRAYGLMMATTSRES-ADTLRLELDGGQMKLTVNLGKGPETLFAGHK- 777
Query: 168 VNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGGKDKGRL---- 223
+ND ++H VR R G + L VDN V F+ I G + R
Sbjct: 778 LNDNEWHTVRVVRRGKSLQLSVDNVTVEGQMAGAHMRLEFH---NIETGIMTERRFISVV 834
Query: 224 ---FQGQLSGLYYDGLKVLNMAAENN 246
F G LSGL ++G ++ + +
Sbjct: 835 PSNFIGHLSGLVFNGQPYMDQCKDGD 860
Score = 35.0 bits (79), Expect = 0.13
Identities = 27/124 (21%), Positives = 58/124 (46%), Gaps = 13/124 (10%)
Query: 109 RSDRLAVGFSTTVKDGILVRID-----------SAPGLGDFLQLHIEQGKIGVVFNIGTV 157
R+ +++ F TT +G+L+ S+ D+ + + G + ++ ++G+
Sbjct: 482 RTGSISLDFRTTEPNGLLLFSQGRRAGGGAGSHSSAQRADYFAMELLDGHLYLLLDMGSG 541
Query: 158 DISIKEERTPVNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGG 217
I ++ VNDG++ V F R+G ++ V N TG I + ++++ +GG
Sbjct: 542 GIKLRASSRKVNDGEWCHVDFQRDGRKGSISV-NSRSTPFLATG-DSEILDLESELYLGG 599
Query: 218 KDKG 221
+G
Sbjct: 600 LPEG 603
>gi|14211536 neurexin 2 isoform alpha-1 precursor [Homo sapiens]
Length = 1712
Score = 331 bits (848), Expect = 9e-91
Identities = 171/283 (60%), Positives = 206/283 (72%), Gaps = 36/283 (12%)
Query: 84 GATYIFGKSGGLILYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHI 143
G TYIFGK G LI YTWP NDRPSTR DRLAVGFST + +LVR+DSA GLGD+LQLHI
Sbjct: 1136 GTTYIFGKGGALITYTWPPNDRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHI 1195
Query: 144 EQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPT--- 200
+QG +GV+FN+GT DI+I E V+DGKYHVVRFTR+GGNATLQVD+WPVNE YP
Sbjct: 1196 DQGTVGVIFNVGTDDITIDEPNAIVSDGKYHVVRFTRSGGNATLQVDSWPVNERYPAGNF 1255
Query: 201 ---------------------------GRQLTIFNTQAQIAIGGKDKGRLFQGQLSGLYY 233
GRQLTIFN+QA I IGG+D+GR FQGQ+SGLYY
Sbjct: 1256 DNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQAAIKIGGRDQGRPFQGQVSGLYY 1315
Query: 234 DGLKVLNMAAENNPNIKINGSVRLVGEVPSILGTTQT--TSMPPEMSTTVMETTTTMATT 291
+GLKVL +AAE++PN++ G +RLVGE PS+L + +T T++ +M+TT+METTTTMATT
Sbjct: 1316 NGLKVLALAAESDPNVRTEGHLRLVGEGPSVLLSAETTATTLLADMATTIMETTTTMATT 1375
Query: 292 TTRKNRS----TASIQPTSDDLVSSAECSSDDEDFVECEPSTG 330
TTR+ RS ++ Q T D LV+SAEC SDDED ECEPSTG
Sbjct: 1376 TTRRGRSPTLRDSTTQNTDDLLVASAECPSDDEDLEECEPSTG 1418
Score = 155 bits (392), Expect = 7e-38
Identities = 80/102 (78%), Positives = 90/102 (88%), Gaps = 1/102 (0%)
Query: 332 SANPTEPGIRRVPGASEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQV 391
+ANPT PG R PGA EVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQV
Sbjct: 1611 TANPTGPGERGPPGAVEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQV 1670
Query: 392 DETRNYISNSAQSNGTLMKEKQQSS-KSGHKKQKNKDREYYV 432
D++RNYISNSAQSNG ++KEK ++ K+ K +KNKD+EYYV
Sbjct: 1671 DQSRNYISNSAQSNGAVVKEKAPAAPKTPSKAKKNKDKEYYV 1712
Score = 50.4 bits (119), Expect = 3e-06
Identities = 36/106 (33%), Positives = 58/106 (54%), Gaps = 7/106 (6%)
Query: 117 FSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIK-EERTPVNDGKYHV 175
F TT DG+L+ +S G DF+ + + +G I VF++G +K PVND ++H
Sbjct: 946 FKTTAPDGLLL-FNSGNG-NDFIVIELVKGYIHYVFDLGNGPSLMKGNSDKPVNDNQWHN 1003
Query: 176 VRFTRNGGNA-TLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGGKDK 220
V +R+ GN TL++D+ V +H R L + + ++ IGG K
Sbjct: 1004 VVVSRDPGNVHTLKIDSRTVTQHSNGARNLDL---KGELYIGGLSK 1046
Score = 39.3 bits (90), Expect = 0.007
Identities = 23/81 (28%), Positives = 40/81 (49%), Gaps = 1/81 (1%)
Query: 110 SDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTPVN 169
S L+ T +L+ +D G DFL+L + G++ + F + + + + TPV
Sbjct: 50 SGELSFSLRTNATRALLLYLDDG-GDCDFLELLLVDGRLRLRFTLSCAEPATLQLDTPVA 108
Query: 170 DGKYHVVRFTRNGGNATLQVD 190
D ++H+V TR+ L VD
Sbjct: 109 DDRWHMVLLTRDARRTALAVD 129
Score = 38.9 bits (89), Expect = 0.009
Identities = 39/176 (22%), Positives = 72/176 (40%), Gaps = 34/176 (19%)
Query: 110 SDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGT--VDISIKEERTP 167
+D + + F T ++G+++ + D++ L ++ G + +V N+G+ + ++
Sbjct: 311 TDEITLAFRTLQRNGLMLHTGKS---ADYVNLSLKSGAVWLVINLGSGAFEALVEPVNGK 367
Query: 168 VNDGKYHVVRFTRN------GGNA---------TLQVDNWPVNEHYPTGRQLTIFNTQAQ 212
ND +H VR TRN G+A T+ VD Y T T+ +
Sbjct: 368 FNDNAWHDVRVTRNLRQHAGIGHAMVNKLHYLVTISVDGILTTTGY-TQEDYTMLGSDDF 426
Query: 213 IAIGGKDK---------GRLFQGQLSGLYYDG----LKVLNMAAENNPNIKINGSV 255
IGG F G L + Y L++ +A E +P +K+ G +
Sbjct: 427 FYIGGSPNTADLPGSPVSNNFMGCLKDVVYKNNDFKLELSRLAKEGDPKMKLQGDL 482
Score = 36.6 bits (83), Expect = 0.045
Identities = 33/154 (21%), Positives = 64/154 (41%), Gaps = 19/154 (12%)
Query: 108 TRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTP 167
T ++ +++ F + G+++ S D L+L ++ G++ + N+ + + + P
Sbjct: 751 TEAEDVSLRFMSQRAYGLMMATTSRES-ADTLRLELDGGQMKLTVNLDCLRVGCAPSKGP 809
Query: 168 --------VNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGGKD 219
+ND ++H VR R G + L VDN V F+ I G
Sbjct: 810 ETLFAGHKLNDNEWHTVRVVRRGKSLQLSVDNVTVEGQMAGAHMRLEFH---NIETGIMT 866
Query: 220 KGRL-------FQGQLSGLYYDGLKVLNMAAENN 246
+ R F G LSGL ++G ++ + +
Sbjct: 867 ERRFISVVPSNFIGHLSGLVFNGQPYMDQCKDGD 900
Score = 35.0 bits (79), Expect = 0.13
Identities = 27/124 (21%), Positives = 58/124 (46%), Gaps = 13/124 (10%)
Query: 109 RSDRLAVGFSTTVKDGILVRID-----------SAPGLGDFLQLHIEQGKIGVVFNIGTV 157
R+ +++ F TT +G+L+ S+ D+ + + G + ++ ++G+
Sbjct: 513 RTGSISLDFRTTEPNGLLLFSQGRRAGGGAGSHSSAQRADYFAMELLDGHLYLLLDMGSG 572
Query: 158 DISIKEERTPVNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGG 217
I ++ VNDG++ V F R+G ++ V N TG I + ++++ +GG
Sbjct: 573 GIKLRASSRKVNDGEWCHVDFQRDGRKGSISV-NSRSTPFLATG-DSEILDLESELYLGG 630
Query: 218 KDKG 221
+G
Sbjct: 631 LPEG 634
>gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo
sapiens]
Length = 1308
Score = 50.4 bits (119), Expect = 3e-06
Identities = 43/178 (24%), Positives = 73/178 (41%), Gaps = 22/178 (12%)
Query: 111 DRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTPVN- 169
D +++ F T DGIL+ + G D + L + + ++ ++ N G + + T VN
Sbjct: 206 DIISLKFKTMQSDGILLHREGPNG--DHITLQLRRARLFLLINSG--EAKLPSTSTLVNL 261
Query: 170 -------DGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGG----- 217
D +H V R G VD H+ + + N +I+ GG
Sbjct: 262 TLGSLLDDQHWHSVLIQRLGKQVNFTVDEH--RHHFHARGEFNLMNLDYEISFGGIPAPG 319
Query: 218 ---KDKGRLFQGQLSGLYYDGLKVLNMAAENNPNIKINGSVRLVGEVPSILGTTQTTS 272
R F G L LYY+G+ ++++A + P I G+V P + T +S
Sbjct: 320 KSVSFPHRNFHGCLENLYYNGVDIIDLAKQQKPQIIAMGNVSFSCSQPQSMPVTFLSS 377
Score = 41.2 bits (95), Expect = 0.002
Identities = 36/140 (25%), Positives = 63/140 (45%), Gaps = 11/140 (7%)
Query: 117 FSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNI----GTVDISIKEERTPVNDGK 172
F TT G+ + G+ DF+++ + + V F+ G +IS++ T ND +
Sbjct: 821 FKTTASSGVFLE---NLGIADFIRIELRSPTV-VTFSFDVGNGPFEISVQSP-THFNDNQ 875
Query: 173 YHVVRFTRNGGNATLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGG-KDKGRLFQGQLSGL 231
+H VR RN A+LQVD + +Q+ +GG + R F G + L
Sbjct: 876 WHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATRQRGFLGCIRSL 935
Query: 232 YYDGLKV-LNMAAENNPNIK 250
+G+ + L A+ P ++
Sbjct: 936 QLNGMTLDLEERAQVTPEVQ 955
>gi|4505463 contactin associated protein 1 precursor [Homo sapiens]
Length = 1384
Score = 49.3 bits (116), Expect = 7e-06
Identities = 56/234 (23%), Positives = 98/234 (41%), Gaps = 32/234 (13%)
Query: 54 QHEHHFHGSKHHS--VPISIY-RSPVSLRGGHAGATY----IFGKSGGLILYTWPANDRP 106
+H+ HFH + + VP++ R + LR G G Y ++ I Y +P R
Sbjct: 134 RHDLHFHFTARYIRIVPLAWNPRGKIGLRLGLYGCPYKADILYFDGDDAISYRFP---RG 190
Query: 107 STRS--DRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEE 164
+RS D A F T KDG+L+ + A GD++ L +E + + ++G+ I +
Sbjct: 191 VSRSLWDVFAFSFKTEEKDGLLLHAEGAQ--GDYVTLELEGAHLLLHMSLGSSPIQPRPG 248
Query: 165 RTPV------NDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGGK 218
T V ND +H VR R G + +D + + + N ++ IGG
Sbjct: 249 HTTVSAGGVLNDQHWHYVRVDRFGRDVNFTLDGYV--QRFILNGDFERLNLDTEMFIGGL 306
Query: 219 DKG--------RLFQGQLSGLYYDGLKVLNMAAENNPNIKINGSV--RLVGEVP 262
F+G + + ++ + + ++A + I G V R + VP
Sbjct: 307 VGAARKNLAYRHNFRGCIENVIFNRVNIADLAVRRHSRITFEGKVAFRCLDPVP 360
Score = 38.5 bits (88), Expect = 0.012
Identities = 32/127 (25%), Positives = 58/127 (45%), Gaps = 13/127 (10%)
Query: 81 GHAGATYIFGKSG-GLILYTWPANDRP---------STRSDRLAVGFSTTVKDGILVRID 130
G+ Y+ G G G L +P RP + + ++ FST+ +L+ +
Sbjct: 1042 GYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGPVYNVTGEEVSFSFSTSSAPAVLLYVS 1101
Query: 131 SAPGLGDFLQLHI-EQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTRNGGNATLQV 189
S + D++ + I + G + + + +GT + PV DG+ H + TR N +QV
Sbjct: 1102 SF--VRDYMAVLIKDDGTLQLRYQLGTSPYVYQLTTRPVTDGQPHSINITRVYRNLFIQV 1159
Query: 190 DNWPVNE 196
D +P+ E
Sbjct: 1160 DYFPLTE 1166
>gi|7662350 cell recognition molecule Caspr2 precursor [Homo
sapiens]
Length = 1331
Score = 45.1 bits (105), Expect = 1e-04
Identities = 32/154 (20%), Positives = 69/154 (44%), Gaps = 18/154 (11%)
Query: 103 NDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIK 162
N + T D +A+ F T+ +G+++ + GD++ L +++ K+ + N+G+ +
Sbjct: 202 NKKMKTLKDVIALNFKTSESEGVILHGEGQQ--GDYITLELKKAKLVLSLNLGSNQLGPI 259
Query: 163 EERTPV------NDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGRQLTIFNTQAQIAIG 216
T V +D +H V R G + L +D +H+ T + + +I G
Sbjct: 260 YGHTSVMTGSLLDDHHWHSVVIERQGRSINLTLDR--SMQHFRTNGEFDYLDLDYEITFG 317
Query: 217 G--------KDKGRLFQGQLSGLYYDGLKVLNMA 242
G + F+G + + Y+G+ + ++A
Sbjct: 318 GIPFSGKPSSSSRKNFKGCMESINYNGVNITDLA 351
Score = 45.1 bits (105), Expect = 1e-04
Identities = 73/319 (22%), Positives = 125/319 (39%), Gaps = 70/319 (21%)
Query: 103 NDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQ-GKIGVVFNIGTV--DI 159
N P + + FSTT IL+ I S DFL + ++ G + + +N+G
Sbjct: 1041 NSHPDLAQEEIRFSFSTTKAPCILLYISSFTT--DFLAVLVKPTGSLQIRYNLGGTREPY 1098
Query: 160 SIKEERTPVNDGKYHVVRFTRNGGNATLQVDNWP-VNEHYPTGRQLTIFNTQAQIAIGGK 218
+I + + +G+ H V TR+ L++D++P V+ H P+ T+FN+ + +G
Sbjct: 1099 NIDVDHRNMANGQPHSVNITRHEKTIFLKLDHYPSVSYHLPSSSD-TLFNSPKSLFLGKV 1157
Query: 219 -DKGRL-----------FQGQLSGLYYDGLKVLNMAAENNPNIKINGSVRLVGE-VPSIL 265
+ G++ F G LS + ++ + L A + V + GE V S
Sbjct: 1158 IETGKIDQEIHKYNTPGFTGCLSRVQFNQIAPLKAALRQT---NASAHVHIQGELVESNC 1214
Query: 266 GTTQTTSMPPEMSTTVMETTTTMATTTTRKNRSTASIQPTSDDLVSSAECSSDDEDFVEC 325
G + T P +T P D + SA DF
Sbjct: 1215 GASPLTLSPMSSAT-----------------------DPWHLDHLDSASA-----DF--- 1243
Query: 326 EPSTGRSANPTEPGIRRVPGASEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRD 385
P PG + + +S+ G V+ +V LC L+ L +Y R
Sbjct: 1244 ---------PYNPG--QGQAIRNGVNRNSAIIGGVIAVVIFTILCTLVFL---IRYMFRH 1289
Query: 386 EGSYQVDETRNYISNSAQS 404
+G+Y +E + + SA+S
Sbjct: 1290 KGTYHTNEAKG--AESAES 1306
Score = 41.6 bits (96), Expect = 0.001
Identities = 29/105 (27%), Positives = 49/105 (46%), Gaps = 2/105 (1%)
Query: 134 GLGDFLQLHIEQG-KIGVVFNIGTVDISIK-EERTPVNDGKYHVVRFTRNGGNATLQVDN 191
G DF++L ++ ++ F++G + I TP+ND ++H V RN A+LQVD
Sbjct: 841 GKEDFIKLELKSATEVSFSFDVGNGPVEIVVRSPTPLNDDQWHRVTAERNVKQASLQVDR 900
Query: 192 WPVNEHYPTGRQLTIFNTQAQIAIGGKDKGRLFQGQLSGLYYDGL 236
P T +Q+ +GG + F G + L +G+
Sbjct: 901 LPQQIRKAPTEGHTRLELYSQLFVGGAGGQQGFLGCIRSLRMNGV 945
Score = 35.8 bits (81), Expect = 0.078
Identities = 26/79 (32%), Positives = 41/79 (51%), Gaps = 9/79 (11%)
Query: 117 FSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNI-----GTVDISIKEERTPVNDG 171
F T +G+LV A LG+ +++ + + K+GV NI +DIS + +NDG
Sbjct: 401 FRTWNPNGLLVFSHFADNLGN-VEIDLTESKVGVHINITQTKMSQIDIS---SGSGLNDG 456
Query: 172 KYHVVRFTRNGGNATLQVD 190
++H VRF A L +D
Sbjct: 457 QWHEVRFLAKENFAILTID 475
>gi|33469935 EGF-like, fibronectin type III and laminin G domains
isoform 3 [Homo sapiens]
Length = 375
Score = 44.3 bits (103), Expect = 2e-04
Identities = 34/117 (29%), Positives = 56/117 (47%), Gaps = 8/117 (6%)
Query: 105 RPSTRSDRLAVGFSTTVKDGILVRIDSAPGL--GDFLQLHIEQGKIGVVFNIGTVDISIK 162
R S + + F TT KDG+L+ +P DF+ L + G + +N+G+ SI
Sbjct: 214 RVSGSRSNVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLGLRDGALVFSYNLGSGVASIM 273
Query: 163 EERTPVNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTG--RQLTIFNTQAQIAIGG 217
+ NDG++H V+ R+G + + VD++ G RQL N + +GG
Sbjct: 274 VNGS-FNDGRWHRVKAVRDGQSGKITVDDYGARTGKSPGMMRQL---NINGALYVGG 326
>gi|33469931 EGF-like, fibronectin type III and laminin G domains
isoform 2 [Homo sapiens]
Length = 775
Score = 44.3 bits (103), Expect = 2e-04
Identities = 34/117 (29%), Positives = 56/117 (47%), Gaps = 8/117 (6%)
Query: 105 RPSTRSDRLAVGFSTTVKDGILVRIDSAPGL--GDFLQLHIEQGKIGVVFNIGTVDISIK 162
R S + + F TT KDG+L+ +P DF+ L + G + +N+G+ SI
Sbjct: 614 RVSGSRSNVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLGLRDGALVFSYNLGSGVASIM 673
Query: 163 EERTPVNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTG--RQLTIFNTQAQIAIGG 217
+ NDG++H V+ R+G + + VD++ G RQL N + +GG
Sbjct: 674 VNGS-FNDGRWHRVKAVRDGQSGKITVDDYGARTGKSPGMMRQL---NINGALYVGG 726
Score = 40.8 bits (94), Expect = 0.002
Identities = 26/86 (30%), Positives = 46/86 (53%), Gaps = 2/86 (2%)
Query: 107 STRSDRLAVGFSTTVKDGILVRI-DSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEER 165
S ++ ++ + F +DG+L+ ++ G GDF+ L I + + FN GT ++I
Sbjct: 171 SYQAFQITLEFRAEAEDGLLLYCGENEHGRGDFMSLAIIRRSLQFRFNCGT-GVAIIVSE 229
Query: 166 TPVNDGKYHVVRFTRNGGNATLQVDN 191
T + G +H V R+G N LQ++N
Sbjct: 230 TKIKLGGWHTVMLYRDGLNGLLQLNN 255
>gi|33469929 EGF-like, fibronectin type III and laminin G domains
isoform 1 [Homo sapiens]
Length = 1009
Score = 44.3 bits (103), Expect = 2e-04
Identities = 34/117 (29%), Positives = 56/117 (47%), Gaps = 8/117 (6%)
Query: 105 RPSTRSDRLAVGFSTTVKDGILVRIDSAPGL--GDFLQLHIEQGKIGVVFNIGTVDISIK 162
R S + + F TT KDG+L+ +P DF+ L + G + +N+G+ SI
Sbjct: 848 RVSGSRSNVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLGLRDGALVFSYNLGSGVASIM 907
Query: 163 EERTPVNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTG--RQLTIFNTQAQIAIGG 217
+ NDG++H V+ R+G + + VD++ G RQL N + +GG
Sbjct: 908 VNGS-FNDGRWHRVKAVRDGQSGKITVDDYGARTGKSPGMMRQL---NINGALYVGG 960
Score = 40.8 bits (94), Expect = 0.002
Identities = 26/86 (30%), Positives = 46/86 (53%), Gaps = 2/86 (2%)
Query: 107 STRSDRLAVGFSTTVKDGILVRI-DSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEER 165
S ++ ++ + F +DG+L+ ++ G GDF+ L I + + FN GT ++I
Sbjct: 405 SYQAFQITLEFRAEAEDGLLLYCGENEHGRGDFMSLAIIRRSLQFRFNCGT-GVAIIVSE 463
Query: 166 TPVNDGKYHVVRFTRNGGNATLQVDN 191
T + G +H V R+G N LQ++N
Sbjct: 464 TKIKLGGWHTVMLYRDGLNGLLQLNN 489
>gi|33469937 EGF-like, fibronectin type III and laminin G domains
isoform 4 [Homo sapiens]
Length = 152
Score = 43.9 bits (102), Expect = 3e-04
Identities = 32/105 (30%), Positives = 52/105 (49%), Gaps = 8/105 (7%)
Query: 117 FSTTVKDGILVRIDSAPGL--GDFLQLHIEQGKIGVVFNIGTVDISIKEERTPVNDGKYH 174
F TT KDG+L+ +P DF+ L + G + +N+G+ SI + NDG++H
Sbjct: 3 FKTTAKDGLLLWRGDSPMRPNSDFISLGLRDGALVFSYNLGSGVASIMVNGS-FNDGRWH 61
Query: 175 VVRFTRNGGNATLQVDNWPVNEHYPTG--RQLTIFNTQAQIAIGG 217
V+ R+G + + VD++ G RQL N + +GG
Sbjct: 62 RVKAVRDGQSGKITVDDYGARTGKSPGMMRQL---NINGALYVGG 103
>gi|239743797 PREDICTED: similar to cell recognition molecule CASPR3
[Homo sapiens]
Length = 944
Score = 43.1 bits (100), Expect = 5e-04
Identities = 34/123 (27%), Positives = 56/123 (45%), Gaps = 6/123 (4%)
Query: 117 FSTTVKDGILVRIDSAPGLGDFLQLHIEQG-KIGVVFNIGTVDISIK-EERTPVNDGKYH 174
F TTV G+ + G+ DF+++ + ++ F++G + + TP ND ++H
Sbjct: 554 FKTTVSSGVFME---NLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWH 610
Query: 175 VVRFTRNGGNATLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGG-KDKGRLFQGQLSGLYY 233
VR RN A+LQVD P +Q+ IGG + R F G + L
Sbjct: 611 HVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRGFLGCIRSLQL 670
Query: 234 DGL 236
+G+
Sbjct: 671 NGV 673
>gi|239743754 PREDICTED: hypothetical protein LOC389722 isoform 1
[Homo sapiens]
Length = 1288
Score = 43.1 bits (100), Expect = 5e-04
Identities = 34/123 (27%), Positives = 56/123 (45%), Gaps = 6/123 (4%)
Query: 117 FSTTVKDGILVRIDSAPGLGDFLQLHIEQG-KIGVVFNIGTVDISIK-EERTPVNDGKYH 174
F TTV G+ + G+ DF+++ + ++ F++G + + TP ND ++H
Sbjct: 821 FKTTVSSGVFME---NLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWH 877
Query: 175 VVRFTRNGGNATLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGG-KDKGRLFQGQLSGLYY 233
VR RN A+LQVD P +Q+ IGG + R F G + L
Sbjct: 878 HVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRGFLGCIRSLQL 937
Query: 234 DGL 236
+G+
Sbjct: 938 NGV 940
Score = 35.4 bits (80), Expect = 0.10
Identities = 47/202 (23%), Positives = 80/202 (39%), Gaps = 25/202 (12%)
Query: 87 YIFGKSGGLILYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQG 146
Y G+S +LYT R D +++ F +GIL+ + G + + L + +G
Sbjct: 185 YFDGQSA--LLYTLDKKPLKPIR-DVISLKFKAMQSNGILLHREGQHG--NHITLELIKG 239
Query: 147 KIGVVFNIGTVDISIKEERTPV--------NDGKYHVVRFTRNGGNATLQVDNWPVNEHY 198
K+ VF + + + + PV +D +H V VD H+
Sbjct: 240 KL--VFFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKH--THHF 295
Query: 199 PTGRQLTIFNTQAQIAIGG-KDKGRL-------FQGQLSGLYYDGLKVLNMAAENNPNIK 250
+ + +I+ GG GR F G L LYY+G+ V +A ++ P I
Sbjct: 296 QAKGDSSNLDLNFEISFGGILSPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKPQIL 355
Query: 251 INGSVRLVGEVPSILGTTQTTS 272
+ G+V P + T +S
Sbjct: 356 MMGNVSFSCPQPQTVPVTFLSS 377
>gi|47519929 cell recognition molecule CASPR3 [Homo sapiens]
Length = 1288
Score = 43.1 bits (100), Expect = 5e-04
Identities = 34/123 (27%), Positives = 56/123 (45%), Gaps = 6/123 (4%)
Query: 117 FSTTVKDGILVRIDSAPGLGDFLQLHIEQG-KIGVVFNIGTVDISIK-EERTPVNDGKYH 174
F TTV G+ + G+ DF+++ + ++ F++G + + TP ND ++H
Sbjct: 821 FKTTVSSGVFME---NLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWH 877
Query: 175 VVRFTRNGGNATLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGG-KDKGRLFQGQLSGLYY 233
VR RN A+LQVD P +Q+ IGG + R F G + L
Sbjct: 878 HVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRGFLGCIRSLQL 937
Query: 234 DGL 236
+G+
Sbjct: 938 NGV 940
Score = 35.4 bits (80), Expect = 0.10
Identities = 38/178 (21%), Positives = 71/178 (39%), Gaps = 22/178 (12%)
Query: 111 DRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTPV-- 168
D +++ F +GIL+ + G + + L + +GK+ VF + + + + PV
Sbjct: 206 DVISLKFKAMQSNGILLHREGQHG--NHITLELIKGKL--VFFLNSGNAKLPSTIAPVTL 261
Query: 169 ------NDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGGKD--- 219
+D +H V VD H+ + + +I+ GG
Sbjct: 262 TLGSLLDDQHWHSVLIELLDTQVNFTVDKH--THHFQAKGDSSYLDLNFEISFGGIPTPG 319
Query: 220 -----KGRLFQGQLSGLYYDGLKVLNMAAENNPNIKINGSVRLVGEVPSILGTTQTTS 272
+ + F G L LYY+G+ V +A ++ P I + G+V P + T +S
Sbjct: 320 RSRAFRRKSFHGCLENLYYNGVDVTELAKKHKPQILMMGNVSFSCPQPQTVPVTFLSS 377
>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
Length = 3075
Score = 42.7 bits (99), Expect = 6e-04
Identities = 22/94 (23%), Positives = 46/94 (48%), Gaps = 1/94 (1%)
Query: 107 STRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERT 166
ST + L + T D +L + S+ DFL + + +G++ ++++G+ ++
Sbjct: 2136 STNYNTLTLNVKTQEPDNLLFYLGSSTA-SDFLAVEMRRGRVAFLWDLGSGSTRLEFPDF 2194
Query: 167 PVNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPT 200
P++D ++H + R G +L V N+ PT
Sbjct: 2195 PIDDNRWHSIHVARFGNIGSLSVKEMSSNQKSPT 2228
Score = 36.2 bits (82), Expect = 0.059
Identities = 48/189 (25%), Positives = 83/189 (43%), Gaps = 41/189 (21%)
Query: 36 SSNVASSSSTSSSPGSHSQHEHH-----FHGSKHHSVPISIYRSP---VSLRGGHAGATY 87
SSN S + TS SPG+ + + + F G + I +SP V+ G G +
Sbjct: 2221 SSNQKSPTKTSKSPGTANVLDVNNSTLMFVGG----LGGQIKKSPAVKVTHFKGCLGEAF 2276
Query: 88 IFGKSGGLILYTW-----------PANDRPSTRSD----------------RLAVGFSTT 120
+ GKS GL Y N+ PS D ++ + F+T
Sbjct: 2277 LNGKSIGLWNYIEREGKCRGCFGSSQNEDPSFHFDGSGYSVVEKSLPATVTQIIMLFNTF 2336
Query: 121 VKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTR 180
+G+L+ + S G DFL + + +G++ V+ ++G+ I++ +R N+G ++ + F R
Sbjct: 2337 SPNGLLLYLGSY-GTKDFLSIELFRGRVKVMTDLGSGPITLLTDRR-YNNGTWYKIAFQR 2394
Query: 181 NGGNATLQV 189
N L V
Sbjct: 2395 NRKQGVLAV 2403
>gi|18640734 contactin associated protein-like 5 [Homo sapiens]
Length = 1306
Score = 42.7 bits (99), Expect = 6e-04
Identities = 38/180 (21%), Positives = 73/180 (40%), Gaps = 19/180 (10%)
Query: 107 STRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERT 166
ST D +++ F + DG+L + G D + L +++G++ + N+G +
Sbjct: 199 STLKDVISLKFKSMQGDGVLFHGEGQRG--DHITLELQKGRLALHLNLGDSKARLSSSLP 256
Query: 167 P------VNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGGKDK 220
++D +H V R G VD +H+ T + + +++ GG
Sbjct: 257 SATLGSLLDDQHWHSVLIERVGKQVNFTVDKH--TQHFRTKGETDALDIDYELSFGGIPV 314
Query: 221 G--------RLFQGQLSGLYYDGLKVLNMAAENNPNIKINGSVRLVGEVPSILGTTQTTS 272
+ F G + LYY+G+ ++++A I G+V P I+ T S
Sbjct: 315 PGKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQI-YTGNVTFSCSEPQIVPITFVNS 373
Score = 42.4 bits (98), Expect = 8e-04
Identities = 32/125 (25%), Positives = 59/125 (47%), Gaps = 6/125 (4%)
Query: 117 FSTTVKDGILVRIDSAPGLGDFLQLHIEQ-GKIGVVFNIGTVDIS-IKEERTPVNDGKYH 174
F TT G+ + G+ DF++L I +I ++G + + + + +ND ++H
Sbjct: 819 FKTTALSGVFLE---NLGIKDFIRLEISSPSEITFAIDVGNGPVELVVQSPSLLNDNQWH 875
Query: 175 VVRFTRNGGNATLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGG-KDKGRLFQGQLSGLYY 233
VR RN +LQVDN P + + +Q+ +GG + + F G + L+
Sbjct: 876 YVRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNSQLFVGGTSSRQKGFLGCIRSLHL 935
Query: 234 DGLKV 238
+G K+
Sbjct: 936 NGQKM 940
>gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
Length = 1816
Score = 42.0 bits (97), Expect = 0.001
Identities = 41/156 (26%), Positives = 70/156 (44%), Gaps = 22/156 (14%)
Query: 137 DFLQLHIEQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTRNGGNATLQVDNWPVNE 196
DF+ L + G++ +FN+G + I+ + NDG +H V F R + L +D V E
Sbjct: 1511 DFMTLFLAHGRLVYMFNVGHKKLKIRSQE-KYNDGLWHDVIFIRERSSGRLVIDGLRVLE 1569
Query: 197 HYPTGRQLTIFNTQAQIAIGGKDKGRLFQG-QLSGLY-YDGLKVLNMAAENNPNIKINGS 254
+ T + + I +GG G+ + Q++ +Y + G N+++NG+
Sbjct: 1570 ESLPPTEAT-WKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCL---------SNLQLNGA 1619
Query: 255 VRLVGEVPSILGTTQTTSMPPEMSTTVMETTTTMAT 290
SI +QT S+ P MET T +T
Sbjct: 1620 --------SITSASQTFSVTPCFEGP-METGTYFST 1646
Score = 29.3 bits (64), Expect = 7.3
Identities = 22/90 (24%), Positives = 38/90 (42%), Gaps = 12/90 (13%)
Query: 95 LILYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNI 154
L LY P RP T D ++ + S +++ L I+ + V+N+
Sbjct: 854 LSLYMKPPVKRPEL----------TETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNL 903
Query: 155 GTVDISIKEERTPVND--GKYHVVRFTRNG 182
GT D+ I + PV+ + +V+ R G
Sbjct: 904 GTKDVEIPLDSKPVSSWPAYFSIVKIERVG 933
>gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens]
Length = 1823
Score = 42.0 bits (97), Expect = 0.001
Identities = 41/156 (26%), Positives = 70/156 (44%), Gaps = 22/156 (14%)
Query: 137 DFLQLHIEQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTRNGGNATLQVDNWPVNE 196
DF+ L + G++ +FN+G + I+ + NDG +H V F R + L +D V E
Sbjct: 1518 DFMTLFLAHGRLVYMFNVGHKKLKIRSQE-KYNDGLWHDVIFIRERSSGRLVIDGLRVLE 1576
Query: 197 HYPTGRQLTIFNTQAQIAIGGKDKGRLFQG-QLSGLY-YDGLKVLNMAAENNPNIKINGS 254
+ T + + I +GG G+ + Q++ +Y + G N+++NG+
Sbjct: 1577 ESLPPTEAT-WKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCL---------SNLQLNGA 1626
Query: 255 VRLVGEVPSILGTTQTTSMPPEMSTTVMETTTTMAT 290
SI +QT S+ P MET T +T
Sbjct: 1627 --------SITSASQTFSVTPCFEGP-METGTYFST 1653
Score = 29.3 bits (64), Expect = 7.3
Identities = 22/90 (24%), Positives = 38/90 (42%), Gaps = 12/90 (13%)
Query: 95 LILYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNI 154
L LY P RP T D ++ + S +++ L I+ + V+N+
Sbjct: 861 LSLYMKPPVKRPEL----------TETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNL 910
Query: 155 GTVDISIKEERTPVND--GKYHVVRFTRNG 182
GT D+ I + PV+ + +V+ R G
Sbjct: 911 GTKDVEIPLDSKPVSSWPAYFSIVKIERVG 940
>gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
Length = 1816
Score = 42.0 bits (97), Expect = 0.001
Identities = 41/156 (26%), Positives = 70/156 (44%), Gaps = 22/156 (14%)
Query: 137 DFLQLHIEQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTRNGGNATLQVDNWPVNE 196
DF+ L + G++ +FN+G + I+ + NDG +H V F R + L +D V E
Sbjct: 1511 DFMTLFLAHGRLVYMFNVGHKKLKIRSQE-KYNDGLWHDVIFIRERSSGRLVIDGLRVLE 1569
Query: 197 HYPTGRQLTIFNTQAQIAIGGKDKGRLFQG-QLSGLY-YDGLKVLNMAAENNPNIKINGS 254
+ T + + I +GG G+ + Q++ +Y + G N+++NG+
Sbjct: 1570 ESLPPTEAT-WKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCL---------SNLQLNGA 1619
Query: 255 VRLVGEVPSILGTTQTTSMPPEMSTTVMETTTTMAT 290
SI +QT S+ P MET T +T
Sbjct: 1620 --------SITSASQTFSVTPCFEGP-METGTYFST 1646
Score = 29.3 bits (64), Expect = 7.3
Identities = 22/90 (24%), Positives = 38/90 (42%), Gaps = 12/90 (13%)
Query: 95 LILYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNI 154
L LY P RP T D ++ + S +++ L I+ + V+N+
Sbjct: 854 LSLYMKPPVKRPEL----------TETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNL 903
Query: 155 GTVDISIKEERTPVND--GKYHVVRFTRNG 182
GT D+ I + PV+ + +V+ R G
Sbjct: 904 GTKDVEIPLDSKPVSSWPAYFSIVKIERVG 933
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 41.2 bits (95), Expect = 0.002
Identities = 31/116 (26%), Positives = 54/116 (46%), Gaps = 7/116 (6%)
Query: 119 TTVKDGIL----VRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTPVNDGKYH 174
T+ G+L V + A DF+ L ++ G + + +G+ + + E P+NDG++H
Sbjct: 4236 TSTASGLLLWQGVEVGEAGQGKDFISLGLQDGHLVFRYQLGSGEARLVSE-DPINDGEWH 4294
Query: 175 VVRFTRNGGNATLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGG-KDKGRLFQGQLS 229
V R G ++QVD + G + + N + + IGG D L G+ S
Sbjct: 4295 RVTALREGRRGSIQVDGEELVSGRSPGPNVAV-NAKGSVYIGGAPDVATLTGGRFS 4349
>gi|148664242 cell recognition protein CASPR4 isoform 2 [Homo
sapiens]
Length = 1235
Score = 41.2 bits (95), Expect = 0.002
Identities = 36/140 (25%), Positives = 63/140 (45%), Gaps = 11/140 (7%)
Query: 117 FSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNI----GTVDISIKEERTPVNDGK 172
F TT G+ + G+ DF+++ + + V F+ G +IS++ T ND +
Sbjct: 748 FKTTASSGVFLE---NLGIADFIRIELRSPTV-VTFSFDVGNGPFEISVQSP-THFNDNQ 802
Query: 173 YHVVRFTRNGGNATLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGG-KDKGRLFQGQLSGL 231
+H VR RN A+LQVD + +Q+ +GG + R F G + L
Sbjct: 803 WHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATRQRGFLGCIRSL 862
Query: 232 YYDGLKV-LNMAAENNPNIK 250
+G+ + L A+ P ++
Sbjct: 863 QLNGMTLDLEERAQVTPEVQ 882
>gi|239743756 PREDICTED: hypothetical protein LOC389722 isoform 2
[Homo sapiens]
Length = 1207
Score = 40.4 bits (93), Expect = 0.003
Identities = 25/79 (31%), Positives = 41/79 (51%), Gaps = 5/79 (6%)
Query: 117 FSTTVKDGILVRIDSAPGLGDFLQLHIEQG-KIGVVFNIGTVDISIK-EERTPVNDGKYH 174
F TTV G+ + G+ DF+++ + ++ F++G + + TP ND ++H
Sbjct: 820 FKTTVSSGVFME---NLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWH 876
Query: 175 VVRFTRNGGNATLQVDNWP 193
VR RN A+LQVD P
Sbjct: 877 HVRAERNVKGASLQVDQLP 895
Score = 35.4 bits (80), Expect = 0.10
Identities = 47/202 (23%), Positives = 80/202 (39%), Gaps = 25/202 (12%)
Query: 87 YIFGKSGGLILYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQG 146
Y G+S +LYT R D +++ F +GIL+ + G + + L + +G
Sbjct: 185 YFDGQSA--LLYTLDKKPLKPIR-DVISLKFKAMQSNGILLHREGQHG--NHITLELIKG 239
Query: 147 KIGVVFNIGTVDISIKEERTPV--------NDGKYHVVRFTRNGGNATLQVDNWPVNEHY 198
K+ VF + + + + PV +D +H V VD H+
Sbjct: 240 KL--VFFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKH--THHF 295
Query: 199 PTGRQLTIFNTQAQIAIGG-KDKGRL-------FQGQLSGLYYDGLKVLNMAAENNPNIK 250
+ + +I+ GG GR F G L LYY+G+ V +A ++ P I
Sbjct: 296 QAKGDSSNLDLNFEISFGGILSPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKPQIL 355
Query: 251 INGSVRLVGEVPSILGTTQTTS 272
+ G+V P + T +S
Sbjct: 356 MMGNVSFSCPQPQTVPVTFLSS 377
>gi|54873613 agrin [Homo sapiens]
Length = 2045
Score = 38.5 bits (88), Expect = 0.012
Identities = 31/107 (28%), Positives = 51/107 (47%), Gaps = 5/107 (4%)
Query: 112 RLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTPVNDG 171
RLA+ F G+L+ +A G DFL L + G++ + F+ G+ ++ PV G
Sbjct: 1395 RLALEFRALEPQGLLLYNGNARGK-DFLALALLDGRVQLRFDTGSGP-AVLTSAVPVEPG 1452
Query: 172 KYHVVRFTRNGGNATLQVD-NWPVNEHYPTGRQLTIFNTQAQIAIGG 217
++H + +R+ TL VD PV P+G N + +GG
Sbjct: 1453 QWHRLELSRHWRRGTLSVDGETPVLGESPSGTD--GLNLDTDLFVGG 1497
Score = 31.6 bits (70), Expect = 1.5
Identities = 27/104 (25%), Positives = 46/104 (44%), Gaps = 5/104 (4%)
Query: 134 GLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTRNGGNATLQVDNWP 193
G GDF+ L + ++ +++G ++ R PV G + V RNG L+V + P
Sbjct: 1686 GKGDFVSLALRDRRLEFRYDLGK-GAAVIRSREPVTLGAWTRVSLERNGRKGALRVGDGP 1744
Query: 194 -VNEHYPTGRQLTIFNTQAQIAIGG-KDKGRLFQGQLSGLYYDG 235
V P T+ N + + +GG D +L + +DG
Sbjct: 1745 RVLGESPVPH--TVLNLKEPLYVGGAPDFSKLARAAAVSSGFDG 1786
>gi|4504229 glycophorin C isoform 1 [Homo sapiens]
Length = 128
Score = 37.7 bits (86), Expect = 0.020
Identities = 33/144 (22%), Positives = 61/144 (42%), Gaps = 21/144 (14%)
Query: 292 TTRKNRSTA---SIQPTSDDLVSSAECSSDDEDFVECEPSTGRSANPTEPGIRRVPGASE 348
+TR STA S++P A S+ EP G S P P +
Sbjct: 3 STRSPNSTAWPLSLEPDP----GMASASTTMHTTTIAEPDPGMSGWPDGRMETSTPTIMD 58
Query: 349 VIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQVDETRNYISNSAQSNGTL 408
++ ++ G++AA A+ ++ LL+ M +Y R +G+Y +E + + A+S
Sbjct: 59 IV--------VIAGVIAAVAIVLVSLLFVMLRYMYRHKGTYHTNEAKG--TEFAESADAA 108
Query: 409 MKEKQQSSKSGHKKQKNKDREYYV 432
++ +G +K EY++
Sbjct: 109 LQGDPALQDAGDSSRK----EYFI 128
>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
sapiens]
Length = 3118
Score = 37.4 bits (85), Expect = 0.027
Identities = 23/98 (23%), Positives = 51/98 (52%), Gaps = 2/98 (2%)
Query: 92 SGGLILYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVV 151
SGG + T+ + + ++ + V T V D +L + SA + DFL + + +GK+ +
Sbjct: 2150 SGGDCIRTYKPEIKKGSYNN-IVVNVKTAVADNLLFYLGSAKFI-DFLAIEMRKGKVSFL 2207
Query: 152 FNIGTVDISIKEERTPVNDGKYHVVRFTRNGGNATLQV 189
+++G+ ++ ++D ++ + +R G N T+ V
Sbjct: 2208 WDVGSGVGRVEYPDLTIDDSYWYRIVASRTGRNGTISV 2245
Score = 29.3 bits (64), Expect = 7.3
Identities = 27/124 (21%), Positives = 54/124 (43%), Gaps = 17/124 (13%)
Query: 108 TRSDRLAVGFSTT-VKDGIL----VRIDSAPGL---------GDFLQLHIEQGKIGVVFN 153
+R+ +A+ F T VK+ + VR ++ GL DF + + G ++
Sbjct: 2765 SRNSHIAIAFDDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQLRNGLPYFSYD 2824
Query: 154 IGTVDISIKEERTPVNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGRQLTIFNTQAQI 213
+G+ D T +NDG++H ++ R+ L VD + + ++ I + +
Sbjct: 2825 LGSGDTHTMIP-TKINDGQWHKIKIMRSKQEGILYVDG--ASNRTISPKKADILDVVGML 2881
Query: 214 AIGG 217
+GG
Sbjct: 2882 YVGG 2885
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,644,126
Number of Sequences: 37866
Number of extensions: 745125
Number of successful extensions: 5802
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 62
Number of HSP's successfully gapped in prelim test: 104
Number of HSP's that attempted gapping in prelim test: 3618
Number of HSP's gapped (non-prelim): 1966
length of query: 432
length of database: 18,247,518
effective HSP length: 105
effective length of query: 327
effective length of database: 14,271,588
effective search space: 4666809276
effective search space used: 4666809276
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.