BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens] (378 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens] 774 0.0 gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens] 732 0.0 gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens] 732 0.0 gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens] 732 0.0 gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens] 732 0.0 gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens] 732 0.0 gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens] 723 0.0 gi|4503383 dopamine receptor D1 [Homo sapiens] 219 2e-57 gi|4503391 dopamine receptor D5 [Homo sapiens] 211 7e-55 gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens] 209 4e-54 gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens] 209 4e-54 gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens] 207 1e-53 gi|21264324 trace amine associated receptor 1 [Homo sapiens] 204 1e-52 gi|4557265 beta-1-adrenergic receptor [Homo sapiens] 201 9e-52 gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens] 195 6e-50 gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens] 195 6e-50 gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens] 195 6e-50 gi|74275344 trace amine associated receptor 2 isoform 1 [Homo sa... 192 3e-49 gi|74275342 trace amine associated receptor 2 isoform 2 [Homo sa... 190 2e-48 gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens] 188 8e-48 gi|28173558 trace amine associated receptor 6 [Homo sapiens] 178 6e-45 gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens] 177 1e-44 gi|110618256 trace amine associated receptor 9 [Homo sapiens] 177 2e-44 gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens] 174 9e-44 gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens] 174 9e-44 gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens] 174 9e-44 gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens] 174 9e-44 gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo sapi... 174 2e-43 gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens] 171 1e-42 gi|16751917 trace amine associated receptor 8 [Homo sapiens] 170 2e-42 >gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens] Length = 378 Score = 774 bits (1998), Expect = 0.0 Identities = 378/378 (100%), Positives = 378/378 (100%) Query: 1 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV Sbjct: 1 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60 Query: 61 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY Sbjct: 61 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120 Query: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN Sbjct: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180 Query: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 240 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP Sbjct: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 240 Query: 241 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 300 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL Sbjct: 241 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 300 Query: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLSG 360 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLSG Sbjct: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLSG 360 Query: 361 CSPVSSFLLLFCNRPVPV 378 CSPVSSFLLLFCNRPVPV Sbjct: 361 CSPVSSFLLLFCNRPVPV 378 >gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens] Length = 359 Score = 732 bits (1890), Expect = 0.0 Identities = 358/358 (100%), Positives = 358/358 (100%) Query: 1 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV Sbjct: 1 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60 Query: 61 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY Sbjct: 61 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120 Query: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN Sbjct: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180 Query: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 240 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP Sbjct: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 240 Query: 241 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 300 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL Sbjct: 241 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 300 Query: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVL 358 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVL Sbjct: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVL 358 >gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens] Length = 428 Score = 732 bits (1890), Expect = 0.0 Identities = 358/358 (100%), Positives = 358/358 (100%) Query: 1 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV Sbjct: 1 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60 Query: 61 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY Sbjct: 61 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120 Query: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN Sbjct: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180 Query: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 240 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP Sbjct: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 240 Query: 241 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 300 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL Sbjct: 241 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 300 Query: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVL 358 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVL Sbjct: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVL 358 >gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens] Length = 360 Score = 732 bits (1890), Expect = 0.0 Identities = 358/358 (100%), Positives = 358/358 (100%) Query: 1 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV Sbjct: 1 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60 Query: 61 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY Sbjct: 61 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120 Query: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN Sbjct: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180 Query: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 240 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP Sbjct: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 240 Query: 241 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 300 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL Sbjct: 241 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 300 Query: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVL 358 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVL Sbjct: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVL 358 >gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens] Length = 387 Score = 732 bits (1890), Expect = 0.0 Identities = 358/358 (100%), Positives = 358/358 (100%) Query: 1 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV Sbjct: 1 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60 Query: 61 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY Sbjct: 61 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120 Query: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN Sbjct: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180 Query: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 240 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP Sbjct: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 240 Query: 241 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 300 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL Sbjct: 241 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 300 Query: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVL 358 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVL Sbjct: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVL 358 >gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens] Length = 388 Score = 732 bits (1890), Expect = 0.0 Identities = 358/358 (100%), Positives = 358/358 (100%) Query: 1 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV Sbjct: 1 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60 Query: 61 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY Sbjct: 61 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120 Query: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN Sbjct: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180 Query: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 240 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP Sbjct: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 240 Query: 241 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 300 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL Sbjct: 241 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 300 Query: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVL 358 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVL Sbjct: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVL 358 >gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens] Length = 402 Score = 723 bits (1865), Expect = 0.0 Identities = 358/372 (96%), Positives = 358/372 (96%), Gaps = 14/372 (3%) Query: 1 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV Sbjct: 1 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60 Query: 61 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY Sbjct: 61 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120 Query: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDL----------- 169 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDL Sbjct: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQD 180 Query: 170 ---IEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI 226 IEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI Sbjct: 181 FHAIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI 240 Query: 227 QMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFID 286 QMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFID Sbjct: 241 QMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFID 300 Query: 287 YTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPC 346 YTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPC Sbjct: 301 YTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPC 360 Query: 347 STTTINGSTHVL 358 STTTINGSTHVL Sbjct: 361 STTTINGSTHVL 372 >gi|4503383 dopamine receptor D1 [Homo sapiens] Length = 446 Score = 219 bits (559), Expect = 2e-57 Identities = 127/349 (36%), Positives = 190/349 (54%), Gaps = 32/349 (9%) Query: 7 NVSSEEGFGSVE------KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60 N S+ +G G V +++ FLS +IL +LGN LV AV R LR TN+F++ Sbjct: 5 NTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVI 64 Query: 61 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120 SLA +DLLV+VLVMP+ A+ + W +G FC + + D++ +TASI +LC IS+DRY+ Sbjct: 65 SLAVSDLLVAVLVMPWKAVAEIAGFWPFGS-FCNIWVAFDIMCSTASILNLCVISVDRYW 123 Query: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180 AI P Y KMTP +++ W + ISF+P+ W+ + + Sbjct: 124 AI-SSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAET 182 Query: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSE--- 237 C +++ YAI+ SV++FYIP +M++ Y RIY A++ +I L+RA ++ Sbjct: 183 IDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQ 242 Query: 238 -----------SRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFI- 285 S+P+S+ + S R ETK KTL +IMG F CW PFF+ N + PF Sbjct: 243 TTTGNGKPVECSQPESSFKMSFKR---ETKVLKTLSVIMGVFVCCWLPFFILNCILPFCG 299 Query: 286 -----DYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCC 329 + + + F+W G+ NS LNP +YAF N FR+AF +L C Sbjct: 300 SGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAF-NADFRKAFSTLLGC 347 >gi|4503391 dopamine receptor D5 [Homo sapiens] Length = 477 Score = 211 bits (538), Expect = 7e-55 Identities = 133/387 (34%), Positives = 201/387 (51%), Gaps = 34/387 (8%) Query: 19 KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78 +VV L+ +I+ +LGN+LV A+ R LR TN FIVSLA +DL V++LVMP+ A Sbjct: 40 QVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKA 99 Query: 79 IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138 + V W +G FC V + D++ +TASI +LC IS+DRY+AI +P Y+ KMT Sbjct: 100 VAEVAGYWPFG-AFCDVWVAFDIMCSTASILNLCVISVDRYWAI-SRPFRYKRKMTQRMA 157 Query: 139 ALMLGGCWVIPTFISFLPIMQGW--------------NNIGIIDLIEKRKFNQNSNSTYC 184 +M+G W + ISF+P+ W NN+ E+ + + N+ C Sbjct: 158 LVMVGLAWTLSILISFIPVQLNWHRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENC 217 Query: 185 VFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSA- 243 +N+ YAI+ S+++FYIP +M++ Y RIY A+ +I L+RA ++S SA Sbjct: 218 DSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAA 277 Query: 244 ---DQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPG--------- 291 D ++ ETK KTL +IMG F CW PFF+ N + PF G Sbjct: 278 CAPDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVS 337 Query: 292 -QVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTT 350 + F+W G+ NS LNP +YAF N F++ F +L C R P +TV S Sbjct: 338 ETTFDVFVWFGWANSSLNPVIYAF-NADFQKVFAQLLGCSHFCSRTPV---ETVNISNEL 393 Query: 351 INGSTHVLSGCSPVSSFLLLFCNRPVP 377 I+ + ++ ++++ + N P Sbjct: 394 ISYNQDIVFHKEIAAAYIHMMPNAVTP 420 >gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens] Length = 397 Score = 209 bits (531), Expect = 4e-54 Identities = 124/312 (39%), Positives = 176/312 (56%), Gaps = 25/312 (8%) Query: 19 KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78 K+ + L+ +IL+ + GN++V +AV +R+LR + TN FIVSLA DLL+ +LV+PF A Sbjct: 18 KITITVVLAVLILITVAGNVVVCLAVGLNRRLRNL-TNCFIVSLAITDLLLGLLVLPFSA 76 Query: 79 IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138 I + W +G+VFC + TSLDV+L TASI +L ISLDRY A+ PL Y +TP+R+ Sbjct: 77 IYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV-MDPLRYPVLVTPVRV 135 Query: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSV 198 A+ L WVI +SFL I GWN+ N ++ C VN+ Y + + Sbjct: 136 AISLVLIWVISITLSFLSIHLGWNS-------RNETSKGNHTTSKCKVQVNEVYGLVDGL 188 Query: 199 VAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAA 258 V FY+P L+M + YYRI+ A++ A +I + S+ + +T R E KA Sbjct: 189 VTFYLPLLIMCITYYRIFKVARDQAKRINHI------------SSWKAATIR---EHKAT 233 Query: 259 KTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAF-LWLGYINSGLNPFLYAFLNK 317 TL +MG F +CW P+F + +V A LWLGY NS LNP LYA LN+ Sbjct: 234 VTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNR 293 Query: 318 SFRRAFLIILCC 329 FR + + CC Sbjct: 294 DFRTGYQQLFCC 305 >gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens] Length = 359 Score = 209 bits (531), Expect = 4e-54 Identities = 124/312 (39%), Positives = 176/312 (56%), Gaps = 25/312 (8%) Query: 19 KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78 K+ + L+ +IL+ + GN++V +AV +R+LR + TN FIVSLA DLL+ +LV+PF A Sbjct: 18 KITITVVLAVLILITVAGNVVVCLAVGLNRRLRNL-TNCFIVSLAITDLLLGLLVLPFSA 76 Query: 79 IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138 I + W +G+VFC + TSLDV+L TASI +L ISLDRY A+ PL Y +TP+R+ Sbjct: 77 IYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV-MDPLRYPVLVTPVRV 135 Query: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSV 198 A+ L WVI +SFL I GWN+ N ++ C VN+ Y + + Sbjct: 136 AISLVLIWVISITLSFLSIHLGWNS-------RNETSKGNHTTSKCKVQVNEVYGLVDGL 188 Query: 199 VAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAA 258 V FY+P L+M + YYRI+ A++ A +I + S+ + +T R E KA Sbjct: 189 VTFYLPLLIMCITYYRIFKVARDQAKRINHI------------SSWKAATIR---EHKAT 233 Query: 259 KTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAF-LWLGYINSGLNPFLYAFLNK 317 TL +MG F +CW P+F + +V A LWLGY NS LNP LYA LN+ Sbjct: 234 VTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNR 293 Query: 318 SFRRAFLIILCC 329 FR + + CC Sbjct: 294 DFRTGYQQLFCC 305 >gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens] Length = 413 Score = 207 bits (527), Expect = 1e-53 Identities = 115/310 (37%), Positives = 170/310 (54%), Gaps = 15/310 (4%) Query: 26 LSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDI 85 +S ++L + GN+LV+ A+ +L+ + TNYFI SLA ADL++ + V+PFGA ++ + Sbjct: 40 MSLIVLAIVFGNVLVITAIAKFERLQTV-TNYFITSLACADLVMGLAVVPFGAAHILMKM 98 Query: 86 WIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGC 145 W +G +C TS+DVL TASI LC I++DRY+AI P Y++ +T + +++ Sbjct: 99 WTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAI-TSPFKYQSLLTKNKARVIILMV 157 Query: 146 WVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPF 205 W++ SFLPI W + N +N T C F N+ YAI S+V+FY+P Sbjct: 158 WIVSGLTSFLPIQMHWYR-----ATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPL 212 Query: 206 LLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMR-------TETKAA 258 ++MV Y R++ AK +I + D + H +R E KA Sbjct: 213 VIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKAL 272 Query: 259 KTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKS 318 KTL IIMG F LCW PFF+ NIV D + +V+ W+GY+NSG NP +Y + Sbjct: 273 KTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYC-RSPD 331 Query: 319 FRRAFLIILC 328 FR AF +LC Sbjct: 332 FRIAFQELLC 341 >gi|21264324 trace amine associated receptor 1 [Homo sapiens] Length = 339 Score = 204 bits (519), Expect = 1e-52 Identities = 111/306 (36%), Positives = 169/306 (55%), Gaps = 12/306 (3%) Query: 22 LLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIEL 81 L + + +IL ++GNL+V+V++ +QL TN+ I S+A D L+ LVMP+ + Sbjct: 26 LYSLMVLIILTTLVGNLIVIVSISHFKQLHT-PTNWLIHSMATVDFLLGCLVMPYSMVRS 84 Query: 82 VQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALM 141 + W +GEVFC + TS D++L++ASIFHL IS+DRYYA+C PL Y+ KM L I +M Sbjct: 85 AEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVC-DPLRYKAKMNILVICVM 143 Query: 142 LGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAF 201 + W +P +F I N G ++ K + C +K + + +F Sbjct: 144 IFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGG----CSVFFSKISGVLTFMTSF 199 Query: 202 YIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAAKTL 261 YIP +M+ YYRIY+ AKE A I +++ + + E KA KTL Sbjct: 200 YIPGSIMLCVYYRIYLIAKEQARLIS------DANQKLQIGLEMKNGISQSKERKAVKTL 253 Query: 262 CIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRR 321 I+MG F +CW PFF+ ++DPF+ Y +P + +W GY+NS NP +YAF FR+ Sbjct: 254 GIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRK 313 Query: 322 AFLIIL 327 A ++L Sbjct: 314 ALKMML 319 >gi|4557265 beta-1-adrenergic receptor [Homo sapiens] Length = 477 Score = 201 bits (511), Expect = 9e-52 Identities = 126/344 (36%), Positives = 181/344 (52%), Gaps = 41/344 (11%) Query: 26 LSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDI 85 ++ ++L+ + GN+LV+VA+ +L+ + TN FI+SLA ADL++ +LV+PFGA +V Sbjct: 65 MALIVLLIVAGNVLVIVAIAKTPRLQTL-TNLFIMSLASADLVMGLLVVPFGATIVVWGR 123 Query: 86 WIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGC 145 W YG FC + TS+DVL TASI LC I+LDRY AI P Y++ +T R ++ Sbjct: 124 WEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAI-TSPFRYQSLLTRARARGLVCTV 182 Query: 146 WVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPF 205 W I +SFLPI+ W + +R +N + C F+ N+ YAI SVV+FY+P Sbjct: 183 WAISALVSFLPILMHWWRAESDE--ARRCYN---DPKCCDFVTNRAYAIASSVVSFYVPL 237 Query: 206 LLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQS----------------------- 242 +M Y R++ A++ +I +R +RP S Sbjct: 238 CIMAFVYLRVFREAQKQVKKIDSCERRFLGGPARPPSPSPSPVPAPAPPPGPPRPAAAAA 297 Query: 243 --------ADQHSTHRM--RTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQ 292 A + R+ E KA KTL IIMG F LCW PFF+ N+V F VP + Sbjct: 298 TAPLANGRAGKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRELVPDR 357 Query: 293 VWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRR 336 ++ F WLGY NS NP +Y + FR+AF +LCC RR Sbjct: 358 LFVFFNWLGYANSAFNPIIYC-RSPDFRKAFQGLLCCARRAARR 400 >gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens] Length = 432 Score = 195 bits (495), Expect = 6e-50 Identities = 128/349 (36%), Positives = 184/349 (52%), Gaps = 42/349 (12%) Query: 14 FGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLV 73 +G VEKVV+ + L+ + L+ I GN LV+++VC+ ++LR+ +NY IVSLA ADL V+V V Sbjct: 76 YGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQ-PSNYLIVSLALADLSVAVAV 134 Query: 74 MPFGAI-ELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNK 132 MPF ++ +L+ WI+G FC V ++DV+ TASI LC IS+DRY I +PL Y + Sbjct: 135 MPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGIT-RPLTYPVR 193 Query: 133 MTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPY 192 +A M+ W++ I+ LP + GW N N + C+ + Y Sbjct: 194 QNGKCMAKMILSVWLLSASIT-LPPLFGWAQ------------NVNDDKV-CLISQDFGY 239 Query: 193 AITCSVVAFYIPFLLMVLAYYRIYVTAKEHA--HQIQMLQRAGASSE------------- 237 I + VAFYIP +M+ YY+IY A++ A H+ R S Sbjct: 240 TIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEV 299 Query: 238 ------SRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYT--- 288 SR ++ + + E KAA TL II+G F +CW PFF+ + PFI T Sbjct: 300 EECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCS 359 Query: 289 -VPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRR 336 +P V FLWLGY NS +NPF+YAF N+ R + +L C R Sbjct: 360 CIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINR 408 >gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens] Length = 479 Score = 195 bits (495), Expect = 6e-50 Identities = 128/349 (36%), Positives = 184/349 (52%), Gaps = 42/349 (12%) Query: 14 FGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLV 73 +G VEKVV+ + L+ + L+ I GN LV+++VC+ ++LR+ +NY IVSLA ADL V+V V Sbjct: 76 YGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQ-PSNYLIVSLALADLSVAVAV 134 Query: 74 MPFGAI-ELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNK 132 MPF ++ +L+ WI+G FC V ++DV+ TASI LC IS+DRY I +PL Y + Sbjct: 135 MPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGIT-RPLTYPVR 193 Query: 133 MTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPY 192 +A M+ W++ I+ LP + GW N N + C+ + Y Sbjct: 194 QNGKCMAKMILSVWLLSASIT-LPPLFGWAQ------------NVNDDKV-CLISQDFGY 239 Query: 193 AITCSVVAFYIPFLLMVLAYYRIYVTAKEHA--HQIQMLQRAGASSE------------- 237 I + VAFYIP +M+ YY+IY A++ A H+ R S Sbjct: 240 TIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEV 299 Query: 238 ------SRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYT--- 288 SR ++ + + E KAA TL II+G F +CW PFF+ + PFI T Sbjct: 300 EECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCS 359 Query: 289 -VPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRR 336 +P V FLWLGY NS +NPF+YAF N+ R + +L C R Sbjct: 360 CIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINR 408 >gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens] Length = 445 Score = 195 bits (495), Expect = 6e-50 Identities = 128/349 (36%), Positives = 184/349 (52%), Gaps = 42/349 (12%) Query: 14 FGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLV 73 +G VEKVV+ + L+ + L+ I GN LV+++VC+ ++LR+ +NY IVSLA ADL V+V V Sbjct: 76 YGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQ-PSNYLIVSLALADLSVAVAV 134 Query: 74 MPFGAI-ELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNK 132 MPF ++ +L+ WI+G FC V ++DV+ TASI LC IS+DRY I +PL Y + Sbjct: 135 MPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGIT-RPLTYPVR 193 Query: 133 MTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPY 192 +A M+ W++ I+ LP + GW N N + C+ + Y Sbjct: 194 QNGKCMAKMILSVWLLSASIT-LPPLFGWAQ------------NVNDDKV-CLISQDFGY 239 Query: 193 AITCSVVAFYIPFLLMVLAYYRIYVTAKEHA--HQIQMLQRAGASSE------------- 237 I + VAFYIP +M+ YY+IY A++ A H+ R S Sbjct: 240 TIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEV 299 Query: 238 ------SRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYT--- 288 SR ++ + + E KAA TL II+G F +CW PFF+ + PFI T Sbjct: 300 EECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCS 359 Query: 289 -VPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRR 336 +P V FLWLGY NS +NPF+YAF N+ R + +L C R Sbjct: 360 CIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINR 408 >gi|74275344 trace amine associated receptor 2 isoform 1 [Homo sapiens] Length = 351 Score = 192 bits (489), Expect = 3e-49 Identities = 105/311 (33%), Positives = 173/311 (55%), Gaps = 25/311 (8%) Query: 19 KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78 +V + +F++ I + I GNL +++++ + +QL TN+ I+S+A D L+ +MP+ Sbjct: 43 RVAMYSFMAGSIFITIFGNLAMIISISYFKQLHT-PTNFLILSMAITDFLLGFTIMPYSM 101 Query: 79 IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138 I V++ W +G FC + S D++L+ SIFHLC +++DR+YAIC PL+Y K+T I Sbjct: 102 IRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAIC-YPLLYSTKITIPVI 160 Query: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGI--IDLIEKRKFNQNSNSTYCVFMVNKPYAITC 196 +L CW +P +F + GI D++ + S+ C M NK + T Sbjct: 161 KRLLLLCWSVPGAFAFGVVFSEAYADGIEGYDILV-------ACSSSCPVMFNKLWGTTL 213 Query: 197 SVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETK 256 + F+ P +MV Y +I+ +++HAH I L+ ++ ++++ + K Sbjct: 214 FMAGFFTPGSMMVGIYGKIFAVSRKHAHAINNLR--------------ENQNNQVKKDKK 259 Query: 257 AAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLN 316 AAKTL I++G F LCW P F T ++DPF++++ P ++ A W GY NS NP +Y F Sbjct: 260 AAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDALTWFGYFNSTCNPLIYGFFY 319 Query: 317 KSFRRAFLIIL 327 FRRA IL Sbjct: 320 PWFRRALKYIL 330 >gi|74275342 trace amine associated receptor 2 isoform 2 [Homo sapiens] Length = 306 Score = 190 bits (483), Expect = 2e-48 Identities = 104/308 (33%), Positives = 171/308 (55%), Gaps = 25/308 (8%) Query: 22 LLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIEL 81 + +F++ I + I GNL +++++ + +QL TN+ I+S+A D L+ +MP+ I Sbjct: 1 MYSFMAGSIFITIFGNLAMIISISYFKQLHT-PTNFLILSMAITDFLLGFTIMPYSMIRS 59 Query: 82 VQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALM 141 V++ W +G FC + S D++L+ SIFHLC +++DR+YAIC PL+Y K+T I + Sbjct: 60 VENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAIC-YPLLYSTKITIPVIKRL 118 Query: 142 LGGCWVIPTFISFLPIMQGWNNIGI--IDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVV 199 L CW +P +F + GI D++ + S+ C M NK + T + Sbjct: 119 LLLCWSVPGAFAFGVVFSEAYADGIEGYDILV-------ACSSSCPVMFNKLWGTTLFMA 171 Query: 200 AFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAAK 259 F+ P +MV Y +I+ +++HAH I L+ ++ ++++ + KAAK Sbjct: 172 GFFTPGSMMVGIYGKIFAVSRKHAHAINNLR--------------ENQNNQVKKDKKAAK 217 Query: 260 TLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSF 319 TL I++G F LCW P F T ++DPF++++ P ++ A W GY NS NP +Y F F Sbjct: 218 TLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDALTWFGYFNSTCNPLIYGFFYPWF 277 Query: 320 RRAFLIIL 327 RRA IL Sbjct: 278 RRALKYIL 285 >gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens] Length = 572 Score = 188 bits (477), Expect = 8e-48 Identities = 132/387 (34%), Positives = 189/387 (48%), Gaps = 47/387 (12%) Query: 16 SVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMP 75 S + V + FL+ ILMA+ GNLLV+++V +R L+ + TNYFIV+LA ADLL+S V+P Sbjct: 93 SAQGVGVGVFLAAFILMAVAGNLLVILSVACNRHLQTV-TNYFIVNLAVADLLLSATVLP 151 Query: 76 FGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTP 135 F A V W +G FC V ++DVL TASI LC IS+DRY + L Y MT Sbjct: 152 FSATMEVLGFWAFGRAFCDVWAAVDVLCCTASILSLCTISVDRYVGV-RHSLKYPAIMTE 210 Query: 136 LRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAIT 195 + A +L WV+ +S P++ GW K + +C YA+ Sbjct: 211 RKAAAILALLWVVALVVSVGPLL-GW------------KEPVPPDERFCGITEEAGYAVF 257 Query: 196 CSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQ--MLQRAGASSE------SRPQSADQHS 247 SV +FY+P ++V+ Y R+YV A+ ++ + + G +SE R + Sbjct: 258 SSVCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGVKRERGKASEVVLRIHCRGAATGADG 317 Query: 248 THRMRT-------------------ETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYT 288 H MR+ E KAAKTL I++G F LCW PFF + Sbjct: 318 AHGMRSAKGHTFRSSLSVRLLKFSREKKAAKTLAIVVGVFVLCWFPFFFVLPLGSLFPQL 377 Query: 289 VPGQ-VWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRP----SILGQT 343 P + V+ WLGY NS +NP +Y ++ F+RAFL +L C R RR + G Sbjct: 378 KPSEGVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQCRRRRRRRPLWRVYGHH 437 Query: 344 VPCSTTTINGSTHVLSGCSPVSSFLLL 370 ST+ + SG +P + L L Sbjct: 438 WRASTSGLRQDCAPSSGDAPPGAPLAL 464 >gi|28173558 trace amine associated receptor 6 [Homo sapiens] Length = 345 Score = 178 bits (452), Expect = 6e-45 Identities = 105/339 (30%), Positives = 171/339 (50%), Gaps = 26/339 (7%) Query: 14 FGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLV 73 F +V+L ++A+ GNLLVM+++ +QL TN+ + SLA AD LV V V Sbjct: 27 FSPGSRVILYIVFGFGAVLAVFGNLLVMISILHFKQLHS-PTNFLVASLACADFLVGVTV 85 Query: 74 MPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKM 133 MPF + V+ W +G FC T DV +S+FHLC IS+DRY A+ PLVY K Sbjct: 86 MPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIAV-TDPLVYPTKF 144 Query: 134 TPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYA 193 T + + W++P S G + G+ +L + C +VN+ + Sbjct: 145 TVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEELSDALNCIGG-----CQTVVNQNWV 199 Query: 194 ITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRT 253 +T ++F+IP +M++ Y I++ A+ A +I + G+ +ES S++ + R Sbjct: 200 LT-DFLSFFIPTFIMIILYGNIFLVARRQAKKI---ENTGSKTES---SSESYKARVARR 252 Query: 254 ETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYA 313 E KAAKTL + + F + W P+ + +++D F+ + P ++ W Y NS +NP +YA Sbjct: 253 ERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCAYYNSAMNPLIYA 312 Query: 314 FLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTIN 352 FR+A +I + GQ + S+ T+N Sbjct: 313 LFYPWFRKAIKVI------------VTGQVLKNSSATMN 339 >gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens] Length = 520 Score = 177 bits (450), Expect = 1e-44 Identities = 117/329 (35%), Positives = 166/329 (50%), Gaps = 40/329 (12%) Query: 26 LSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDI 85 L IL AI+GN+LV+++V +R LR TNYFIV+LA ADLL+S V+PF A V Sbjct: 52 LGAFILFAIVGNILVILSVACNRHLRT-PTNYFIVNLAMADLLLSFTVLPFSAALEVLGY 110 Query: 86 WIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGC 145 W+ G +FC + ++DVL TASI LC IS+DRY + L Y +T + L L Sbjct: 111 WVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGV-RYSLQYPTLVTRRKAILALLSV 169 Query: 146 WVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPF 205 WV+ T IS P++ GW K ++ C YA+ S+ +FYIP Sbjct: 170 WVLSTVISIGPLL-GW------------KEPAPNDDKECGVTEEPFYALFSSLGSFYIPL 216 Query: 206 LLMVLAYYRIYVTAKEHAHQIQ--MLQRAGASSE----------------------SRPQ 241 ++++ Y R+Y+ AK ++ +++ S E P+ Sbjct: 217 AVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPR 276 Query: 242 SADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVT-NIVDPFIDYTVPGQVWTAFLWL 300 S+ + E KAAKTL I++G F LCW PFF+ + F P V+ WL Sbjct: 277 SSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWL 336 Query: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCC 329 GY NS LNP +Y +K F+RAF+ IL C Sbjct: 337 GYFNSCLNPIIYPCSSKEFKRAFVRILGC 365 >gi|110618256 trace amine associated receptor 9 [Homo sapiens] Length = 348 Score = 177 bits (448), Expect = 2e-44 Identities = 106/308 (34%), Positives = 160/308 (51%), Gaps = 16/308 (5%) Query: 21 VLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIE 80 +L L ++A GNLLVM+A+ +QL TN+ I SLA AD LV V VMPF + Sbjct: 34 ILYAVLGFGAVLAAFGNLLVMIAILHFKQLHT-PTNFLIASLACADFLVGVTVMPFSTVR 92 Query: 81 LVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIAL 140 V+ W +G+ +C T D AS+FHLCCIS+DRY A+ PL Y K T + Sbjct: 93 SVESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAV-TDPLTYPTKFTVSVSGI 151 Query: 141 MLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVA 200 + W SF G N GI +L+ C +N+ + + C ++ Sbjct: 152 CIVLSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGG-----CQAPLNQNWVLLCFLL- 205 Query: 201 FYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRM-RTETKAAK 259 F+IP + MV Y +I++ AK A +I+ S+ S+ QS+ + R+ + E KAAK Sbjct: 206 FFIPNVAMVFIYSKIFLVAKHQARKIE-------STASQAQSSSESYKERVAKRERKAAK 258 Query: 260 TLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSF 319 TL I M F + W P+ V ++D ++++ P V+ +W Y NS +NP +YAF + F Sbjct: 259 TLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCVYYNSAMNPLIYAFFYQWF 318 Query: 320 RRAFLIIL 327 +A +I+ Sbjct: 319 GKAIKLIV 326 >gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens] Length = 455 Score = 174 bits (442), Expect = 9e-44 Identities = 111/335 (33%), Positives = 170/335 (50%), Gaps = 38/335 (11%) Query: 16 SVEKVVLL-TFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVM 74 ++ K +LL L +IL +LGN+LV+++V R L + T+Y+IV+LA ADLL++ V+ Sbjct: 22 NISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSV-THYYIVNLAVADLLLTSTVL 80 Query: 75 PFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMT 134 PF AI V W +G VFC + ++DVL TASI LC IS+DRY + PL Y +T Sbjct: 81 PFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGV-SYPLRYPTIVT 139 Query: 135 PLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAI 194 R + L W + IS P+ GW D T C Y + Sbjct: 140 QRRGLMALLCVWALSLVISIGPLF-GWRQPAPED------------ETICQINEEPGYVL 186 Query: 195 TCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQ---------------MLQRAGASSESR 239 ++ +FY+P ++++ Y R+YV AK + ++ + R A + Sbjct: 187 FSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGS 246 Query: 240 PQSADQHSTH------RMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFI-DYTVPGQ 292 ++ + TH + E KAAKTL I++GCF LCW PFF+ + F D+ Sbjct: 247 GMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSET 306 Query: 293 VWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIIL 327 V+ WLGY+NS +NP +Y ++ F++AF +L Sbjct: 307 VFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVL 341 >gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens] Length = 466 Score = 174 bits (442), Expect = 9e-44 Identities = 111/335 (33%), Positives = 170/335 (50%), Gaps = 38/335 (11%) Query: 16 SVEKVVLL-TFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVM 74 ++ K +LL L +IL +LGN+LV+++V R L + T+Y+IV+LA ADLL++ V+ Sbjct: 22 NISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSV-THYYIVNLAVADLLLTSTVL 80 Query: 75 PFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMT 134 PF AI V W +G VFC + ++DVL TASI LC IS+DRY + PL Y +T Sbjct: 81 PFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGV-SYPLRYPTIVT 139 Query: 135 PLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAI 194 R + L W + IS P+ GW D T C Y + Sbjct: 140 QRRGLMALLCVWALSLVISIGPLF-GWRQPAPED------------ETICQINEEPGYVL 186 Query: 195 TCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQ---------------MLQRAGASSESR 239 ++ +FY+P ++++ Y R+YV AK + ++ + R A + Sbjct: 187 FSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGS 246 Query: 240 PQSADQHSTH------RMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFI-DYTVPGQ 292 ++ + TH + E KAAKTL I++GCF LCW PFF+ + F D+ Sbjct: 247 GMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSET 306 Query: 293 VWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIIL 327 V+ WLGY+NS +NP +Y ++ F++AF +L Sbjct: 307 VFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVL 341 >gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens] Length = 475 Score = 174 bits (442), Expect = 9e-44 Identities = 111/335 (33%), Positives = 170/335 (50%), Gaps = 38/335 (11%) Query: 16 SVEKVVLL-TFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVM 74 ++ K +LL L +IL +LGN+LV+++V R L + T+Y+IV+LA ADLL++ V+ Sbjct: 22 NISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSV-THYYIVNLAVADLLLTSTVL 80 Query: 75 PFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMT 134 PF AI V W +G VFC + ++DVL TASI LC IS+DRY + PL Y +T Sbjct: 81 PFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGV-SYPLRYPTIVT 139 Query: 135 PLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAI 194 R + L W + IS P+ GW D T C Y + Sbjct: 140 QRRGLMALLCVWALSLVISIGPLF-GWRQPAPED------------ETICQINEEPGYVL 186 Query: 195 TCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQ---------------MLQRAGASSESR 239 ++ +FY+P ++++ Y R+YV AK + ++ + R A + Sbjct: 187 FSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGS 246 Query: 240 PQSADQHSTH------RMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFI-DYTVPGQ 292 ++ + TH + E KAAKTL I++GCF LCW PFF+ + F D+ Sbjct: 247 GMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSET 306 Query: 293 VWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIIL 327 V+ WLGY+NS +NP +Y ++ F++AF +L Sbjct: 307 VFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVL 341 >gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens] Length = 429 Score = 174 bits (442), Expect = 9e-44 Identities = 111/335 (33%), Positives = 170/335 (50%), Gaps = 38/335 (11%) Query: 16 SVEKVVLL-TFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVM 74 ++ K +LL L +IL +LGN+LV+++V R L + T+Y+IV+LA ADLL++ V+ Sbjct: 22 NISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSV-THYYIVNLAVADLLLTSTVL 80 Query: 75 PFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMT 134 PF AI V W +G VFC + ++DVL TASI LC IS+DRY + PL Y +T Sbjct: 81 PFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGV-SYPLRYPTIVT 139 Query: 135 PLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAI 194 R + L W + IS P+ GW D T C Y + Sbjct: 140 QRRGLMALLCVWALSLVISIGPLF-GWRQPAPED------------ETICQINEEPGYVL 186 Query: 195 TCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQ---------------MLQRAGASSESR 239 ++ +FY+P ++++ Y R+YV AK + ++ + R A + Sbjct: 187 FSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGS 246 Query: 240 PQSADQHSTH------RMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFI-DYTVPGQ 292 ++ + TH + E KAAKTL I++GCF LCW PFF+ + F D+ Sbjct: 247 GMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSET 306 Query: 293 VWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIIL 327 V+ WLGY+NS +NP +Y ++ F++AF +L Sbjct: 307 VFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVL 341 >gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo sapiens] Length = 440 Score = 174 bits (440), Expect = 2e-43 Identities = 108/317 (34%), Positives = 161/317 (50%), Gaps = 25/317 (7%) Query: 26 LSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDI 85 L VI + N L++ +C LR +N+F+VSL +DL+V ++VMP + + Sbjct: 33 LCVVIALTAAANSLLIALICTQPALRNT-SNFFLVSLFTSDLMVGLVVMPPAMLNALYGR 91 Query: 86 WIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGC 145 W+ CL+ T+ DV+ +ASI +LC ISLDRY I PL Y+ +MTPLR ++ G Sbjct: 92 WVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLI-LSPLRYKLRMTPLRALALVLGA 150 Query: 146 WVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPF 205 W + SFLP++ GW+ +G + C + + P+ + S + F++P Sbjct: 151 WSLAALASFLPLLLGWHELG---------HARPPVPGQCRLLASLPFVLVASGLTFFLPS 201 Query: 206 LLMVLAYYRIYVTAKEHAHQIQMLQRAGASSES---------RP--QSADQH--STHRMR 252 + Y RI + A++ A Q+ L AS S RP +SAD +T R Sbjct: 202 GAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVPRTPRPGVESADSRRLATKHSR 261 Query: 253 TETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLY 312 KA+ TL I++G F + W PFFV NIV D PG ++ WLGY NS +NP +Y Sbjct: 262 KALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG-LFDVLTWLGYCNSTMNPIIY 320 Query: 313 AFLNKSFRRAFLIILCC 329 + F+RA L C Sbjct: 321 PLFMRDFKRALGRFLPC 337 >gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens] Length = 408 Score = 171 bits (432), Expect = 1e-42 Identities = 124/380 (32%), Positives = 182/380 (47%), Gaps = 42/380 (11%) Query: 4 LDANVSSEEGFGSV--EKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVS 61 L N ++ G V E + L+ +L + GNLLV+VA+ W +L+ + TN F+ S Sbjct: 20 LAPNTANTSGLPGVPWEAALAGALLALAVLATVGGNLLVIVAIAWTPRLQTM-TNVFVTS 78 Query: 62 LAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYA 121 LA ADL++ +LV+P A + W G C + TS+DVL TASI LC +++DRY A Sbjct: 79 LAAADLVMGLLVVPPAATLALTGHWPLGATGCELWTSVDVLCVTASIETLCALAVDRYLA 138 Query: 122 ICCQPLVYRNKMTP--LRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNS 179 + PL Y +T R A++L WV+ +SF PIM W +G + +S Sbjct: 139 V-TNPLRYGALVTKRCARTAVVL--VWVVSAAVSFAPIMSQWWRVG----ADAEAQRCHS 191 Query: 180 NSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESR 239 N C F N PY + S V+FY+P L+M+ Y R++V A ++ ES Sbjct: 192 NPRCCAFASNMPYVLLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRGELGRFPPEESP 251 Query: 240 PQSADQHSTHRMRT---------------------ETKAAKTLCIIMGCFCLCWAPFFVT 278 P + + + T E +A TL +IMG F LCW PFF+ Sbjct: 252 PAPSRSLAPAPVGTCAPPEGVPACGRRPARLLPLREHRALCTLGLIMGTFTLCWLPFFLA 311 Query: 279 NIVDPFIDYT-VPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERY--- 334 N++ + VPG + A WLGY NS NP +Y + FR AF +LC R Sbjct: 312 NVLRALGGPSLVPGPAFLALNWLGYANSAFNPLIYC-RSPDFRSAFRRLLCRCGRRLPPE 370 Query: 335 ----RRPSILGQTVPCSTTT 350 RP++ VP + ++ Sbjct: 371 PCAAARPALFPSGVPAARSS 390 >gi|16751917 trace amine associated receptor 8 [Homo sapiens] Length = 342 Score = 170 bits (430), Expect = 2e-42 Identities = 101/320 (31%), Positives = 161/320 (50%), Gaps = 14/320 (4%) Query: 11 EEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVS 70 E + +V+L T S L+A+ GNLLVM +V +QL TN+ I SLA AD LV Sbjct: 23 ETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFKQLHS-PTNFLIASLACADFLVG 81 Query: 71 VLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYR 130 V VM F + V+ W +G FC + + DV +S+ HLC I +DRY + PLVY Sbjct: 82 VTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIVV-TDPLVYA 140 Query: 131 NKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNK 190 K T + + W++P S G N+ G+ +L+ C +V++ Sbjct: 141 TKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELVSALNCVGG-----CQIIVSQ 195 Query: 191 PYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHR 250 + + + F+IP L+M++ Y +I++ AK+ A +I+ +S S++ + Sbjct: 196 GW-VLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIE------TTSSKVESSSESYKIRV 248 Query: 251 MRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPF 310 + E KAAKTL + + F + W P+ V ++D F+ + P ++ W Y NS +NP Sbjct: 249 AKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSAYYNSAMNPL 308 Query: 311 LYAFLNKSFRRAFLIILCCD 330 +YA FR+A +IL D Sbjct: 309 IYALFYPWFRKAIKLILSGD 328 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.330 0.141 0.456 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,915,828 Number of Sequences: 37866 Number of extensions: 523970 Number of successful extensions: 3446 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 324 Number of HSP's successfully gapped in prelim test: 352 Number of HSP's that attempted gapping in prelim test: 1926 Number of HSP's gapped (non-prelim): 1005 length of query: 378 length of database: 18,247,518 effective HSP length: 104 effective length of query: 274 effective length of database: 14,309,454 effective search space: 3920790396 effective search space used: 3920790396 T: 11 A: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.9 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.