Search of human proteins with 40068038

Search of human proteins with 40068038

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|40068038 B/K protein [Homo sapiens]
         (474 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|40068038 B/K protein [Homo sapiens]                                963   0.0  
gi|209447073 synaptotagmin I [Homo sapiens]                           225   6e-59
gi|5032139 synaptotagmin I [Homo sapiens]                             225   6e-59
gi|209447070 synaptotagmin I [Homo sapiens]                           225   6e-59
gi|211059429 synaptotagmin II [Homo sapiens]                          222   5e-58
gi|31543670 synaptotagmin II [Homo sapiens]                           222   5e-58
gi|38570146 synaptotagmin VII [Homo sapiens]                          213   2e-55
gi|92859638 synaptotagmin V [Homo sapiens]                            209   4e-54
gi|45504376 synaptotagmin VI [Homo sapiens]                           189   4e-48
gi|28376627 synaptotagmin IX [Homo sapiens]                           186   4e-47
gi|39752671 synaptotagmin X [Homo sapiens]                            186   5e-47
gi|238550198 synaptotagmin III [Homo sapiens]                         184   1e-46
gi|238550196 synaptotagmin III [Homo sapiens]                         184   1e-46
gi|14150054 synaptotagmin III [Homo sapiens]                          184   1e-46
gi|216548478 synaptotagmin XI [Homo sapiens]                          174   2e-43
gi|24308219 synaptotagmin IV [Homo sapiens]                           168   1e-41
gi|31881675 synaptotagmin XV isoform a [Homo sapiens]                 145   8e-35
gi|94536846 synaptotagmin VIII [Homo sapiens]                         143   3e-34
gi|29366828 synaptotagmin XII [Homo sapiens]                          142   9e-34
gi|6005997 double C2-like domains, beta [Homo sapiens]                125   1e-28
gi|31881667 synaptotagmin XV isoform b [Homo sapiens]                 120   4e-27
gi|24308233 synaptotagmin XIII [Homo sapiens]                         119   5e-27
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]            116   5e-26
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]             116   5e-26
gi|47078261 double C2-like domains, alpha [Homo sapiens]              110   3e-24
gi|193804862 synaptotagmin-like 4 [Homo sapiens]                       96   7e-20
gi|193804860 synaptotagmin-like 4 [Homo sapiens]                       96   7e-20
gi|239744413 PREDICTED: hypothetical protein LOC390213 [Homo sap...    95   1e-19
gi|123173752 synaptotagmin XIV-like [Homo sapiens]                     92   1e-18
gi|226342962 synaptotagmin XIV isoform 2 [Homo sapiens]                88   1e-17

>gi|40068038 B/K protein [Homo sapiens]
          Length = 474

 Score =  963 bits (2490), Expect = 0.0
 Identities = 474/474 (100%), Positives = 474/474 (100%)

Query: 1   MAYIQLEPLNEGFLSRISGLLLCRWTCRHCCQKCYESSCCQSSEDEVEILGPFPAQTPPW 60
           MAYIQLEPLNEGFLSRISGLLLCRWTCRHCCQKCYESSCCQSSEDEVEILGPFPAQTPPW
Sbjct: 1   MAYIQLEPLNEGFLSRISGLLLCRWTCRHCCQKCYESSCCQSSEDEVEILGPFPAQTPPW 60

Query: 61  LMASRSSDKDGDSVHTASEVPLTPRTNSPDGRRSSSDTSKSTYSLTRRISSLESRRPSSP 120
           LMASRSSDKDGDSVHTASEVPLTPRTNSPDGRRSSSDTSKSTYSLTRRISSLESRRPSSP
Sbjct: 61  LMASRSSDKDGDSVHTASEVPLTPRTNSPDGRRSSSDTSKSTYSLTRRISSLESRRPSSP 120

Query: 121 LIDIKPIEFGVLSAKKEPIQPSVLRRTYNPDDYFRKFEPHLYSLDSNSDDVDSLTDEEIL 180
           LIDIKPIEFGVLSAKKEPIQPSVLRRTYNPDDYFRKFEPHLYSLDSNSDDVDSLTDEEIL
Sbjct: 121 LIDIKPIEFGVLSAKKEPIQPSVLRRTYNPDDYFRKFEPHLYSLDSNSDDVDSLTDEEIL 180

Query: 181 SKYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLLPDQK 240
           SKYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLLPDQK
Sbjct: 181 SKYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLLPDQK 240

Query: 241 NSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSVPLCEV 300
           NSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSVPLCEV
Sbjct: 241 NSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSVPLCEV 300

Query: 301 DLVKGGHWWKALIPSSQNEVELGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGSDPF 360
           DLVKGGHWWKALIPSSQNEVELGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGSDPF
Sbjct: 301 DLVKGGHWWKALIPSSQNEVELGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGSDPF 360

Query: 361 VKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSND 420
           VKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSND
Sbjct: 361 VKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSND 420

Query: 421 FIGRIVIGQYSSGPSETNHWRRMLNTHRTAVEQWHSLRSRAECDRVSPASLEVT 474
           FIGRIVIGQYSSGPSETNHWRRMLNTHRTAVEQWHSLRSRAECDRVSPASLEVT
Sbjct: 421 FIGRIVIGQYSSGPSETNHWRRMLNTHRTAVEQWHSLRSRAECDRVSPASLEVT 474


>gi|209447073 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  225 bits (574), Expect = 6e-59
 Identities = 121/301 (40%), Positives = 183/301 (60%), Gaps = 9/301 (2%)

Query: 165 DSNSDDVDSLTDEEILSKYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDM 224
           D+ +   D    EE   + +LG L +S  YD  +N L V +I+A +LP  +   G+    
Sbjct: 123 DAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPA-LDMGGT---- 177

Query: 225 AHSNPYVKICLLPDQKNSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKF 284
             S+PYVK+ LLPD+K   +T V RKT  PVF E++TF++P+ E   +TL++ V DFD+F
Sbjct: 178 --SDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRF 235

Query: 285 SRHCVIGKVSVPLCEVDLVKGGHWWKALIPSSQNEVE-LGELLLSLNYLPSAGRLNVDVI 343
           S+H +IG+  VP+  VD       W+ L  + + E E LG++  SL Y+P+AG+L V ++
Sbjct: 236 SKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVIL 295

Query: 344 RAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELEN 403
            AK L + DV   SDP+VKI L+   K +K KKT+  + T++P+YNESFSF+VP E+++ 
Sbjct: 296 EAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQK 355

Query: 404 ASLVFTVFGHNMKSSNDFIGRIVIGQYSSGPSETNHWRRMLNTHRTAVEQWHSLRSRAEC 463
             +V TV  ++    ND IG++ +G Y+S  +E  HW  ML   R  + QWH+L+   E 
Sbjct: 356 VQVVVTVLDYDKIGKNDAIGKVFVG-YNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEV 414

Query: 464 D 464
           D
Sbjct: 415 D 415


>gi|5032139 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  225 bits (574), Expect = 6e-59
 Identities = 121/301 (40%), Positives = 183/301 (60%), Gaps = 9/301 (2%)

Query: 165 DSNSDDVDSLTDEEILSKYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDM 224
           D+ +   D    EE   + +LG L +S  YD  +N L V +I+A +LP  +   G+    
Sbjct: 123 DAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPA-LDMGGT---- 177

Query: 225 AHSNPYVKICLLPDQKNSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKF 284
             S+PYVK+ LLPD+K   +T V RKT  PVF E++TF++P+ E   +TL++ V DFD+F
Sbjct: 178 --SDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRF 235

Query: 285 SRHCVIGKVSVPLCEVDLVKGGHWWKALIPSSQNEVE-LGELLLSLNYLPSAGRLNVDVI 343
           S+H +IG+  VP+  VD       W+ L  + + E E LG++  SL Y+P+AG+L V ++
Sbjct: 236 SKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVIL 295

Query: 344 RAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELEN 403
            AK L + DV   SDP+VKI L+   K +K KKT+  + T++P+YNESFSF+VP E+++ 
Sbjct: 296 EAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQK 355

Query: 404 ASLVFTVFGHNMKSSNDFIGRIVIGQYSSGPSETNHWRRMLNTHRTAVEQWHSLRSRAEC 463
             +V TV  ++    ND IG++ +G Y+S  +E  HW  ML   R  + QWH+L+   E 
Sbjct: 356 VQVVVTVLDYDKIGKNDAIGKVFVG-YNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEV 414

Query: 464 D 464
           D
Sbjct: 415 D 415


>gi|209447070 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  225 bits (574), Expect = 6e-59
 Identities = 121/301 (40%), Positives = 183/301 (60%), Gaps = 9/301 (2%)

Query: 165 DSNSDDVDSLTDEEILSKYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDM 224
           D+ +   D    EE   + +LG L +S  YD  +N L V +I+A +LP  +   G+    
Sbjct: 123 DAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPA-LDMGGT---- 177

Query: 225 AHSNPYVKICLLPDQKNSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKF 284
             S+PYVK+ LLPD+K   +T V RKT  PVF E++TF++P+ E   +TL++ V DFD+F
Sbjct: 178 --SDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRF 235

Query: 285 SRHCVIGKVSVPLCEVDLVKGGHWWKALIPSSQNEVE-LGELLLSLNYLPSAGRLNVDVI 343
           S+H +IG+  VP+  VD       W+ L  + + E E LG++  SL Y+P+AG+L V ++
Sbjct: 236 SKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVIL 295

Query: 344 RAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELEN 403
            AK L + DV   SDP+VKI L+   K +K KKT+  + T++P+YNESFSF+VP E+++ 
Sbjct: 296 EAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQK 355

Query: 404 ASLVFTVFGHNMKSSNDFIGRIVIGQYSSGPSETNHWRRMLNTHRTAVEQWHSLRSRAEC 463
             +V TV  ++    ND IG++ +G Y+S  +E  HW  ML   R  + QWH+L+   E 
Sbjct: 356 VQVVVTVLDYDKIGKNDAIGKVFVG-YNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEV 414

Query: 464 D 464
           D
Sbjct: 415 D 415


>gi|211059429 synaptotagmin II [Homo sapiens]
          Length = 419

 Score =  222 bits (566), Expect = 5e-58
 Identities = 119/289 (41%), Positives = 177/289 (61%), Gaps = 9/289 (3%)

Query: 177 EEILSKYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLL 236
           EE      LG L FS  YD   N LTV V++A +LP  +   G+      S+PYVK+ LL
Sbjct: 132 EEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPA-LDMGGT------SDPYVKVFLL 184

Query: 237 PDQKNSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSVP 296
           PD+K   +T V RKT  P F E +TF++P+ E   +TL++ + DFD+FS+H +IG+V VP
Sbjct: 185 PDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVP 244

Query: 297 LCEVDLVKGGHWWKALIPSSQNEVE-LGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQ 355
           +  VDL +    W+ L    + E E LG++  SL Y+P+AG+L V ++ AK L + DV  
Sbjct: 245 MNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGG 304

Query: 356 GSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNM 415
            SDP+VKI L+   K +K KKT+  + T++P++NESFSF++P E+++   +V TV  ++ 
Sbjct: 305 LSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDK 364

Query: 416 KSSNDFIGRIVIGQYSSGPSETNHWRRMLNTHRTAVEQWHSLRSRAECD 464
              N+ IG+I +G  ++G +E  HW  ML   R  + QWHSL+   E D
Sbjct: 365 LGKNEAIGKIFVGSNATG-TELRHWSDMLANPRRPIAQWHSLKPEEEVD 412


>gi|31543670 synaptotagmin II [Homo sapiens]
          Length = 419

 Score =  222 bits (566), Expect = 5e-58
 Identities = 119/289 (41%), Positives = 177/289 (61%), Gaps = 9/289 (3%)

Query: 177 EEILSKYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLL 236
           EE      LG L FS  YD   N LTV V++A +LP  +   G+      S+PYVK+ LL
Sbjct: 132 EEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPA-LDMGGT------SDPYVKVFLL 184

Query: 237 PDQKNSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSVP 296
           PD+K   +T V RKT  P F E +TF++P+ E   +TL++ + DFD+FS+H +IG+V VP
Sbjct: 185 PDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVP 244

Query: 297 LCEVDLVKGGHWWKALIPSSQNEVE-LGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQ 355
           +  VDL +    W+ L    + E E LG++  SL Y+P+AG+L V ++ AK L + DV  
Sbjct: 245 MNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGG 304

Query: 356 GSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNM 415
            SDP+VKI L+   K +K KKT+  + T++P++NESFSF++P E+++   +V TV  ++ 
Sbjct: 305 LSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDK 364

Query: 416 KSSNDFIGRIVIGQYSSGPSETNHWRRMLNTHRTAVEQWHSLRSRAECD 464
              N+ IG+I +G  ++G +E  HW  ML   R  + QWHSL+   E D
Sbjct: 365 LGKNEAIGKIFVGSNATG-TELRHWSDMLANPRRPIAQWHSLKPEEEVD 412


>gi|38570146 synaptotagmin VII [Homo sapiens]
          Length = 403

 Score =  213 bits (543), Expect = 2e-55
 Identities = 124/324 (38%), Positives = 190/324 (58%), Gaps = 27/324 (8%)

Query: 151 DDYFRKFEPHLYSLDSNSDDVDSLTDEEIL--------------SKYQLGMLHFSTQYDL 196
           D+  R+ EP      S SD V+SLT E ++              S+  LG + FS  Y+ 
Sbjct: 92  DESDRRTEPR----SSVSDLVNSLTSEMLMLSPGSEEDEAHEGCSRENLGRIQFSVGYNF 147

Query: 197 LHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLLPDQKNSKQTGVKRKTQKPVF 256
             + LTV++++A++LP       ++     S+P+VKI LLPD+K+  +T VKRK   P +
Sbjct: 148 QESTLTVKIMKAQELP-------AKDFSGTSDPFVKIYLLPDKKHKLETKVKRKNLNPHW 200

Query: 257 EERYTFE-IPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSVPLCEVDLVKGGHWWKALIPS 315
            E + FE  P+ +  +R L L V+D+D+FSR+  IG+VS+PL +VDL +   +WK L P 
Sbjct: 201 NETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTFWKDLKPC 260

Query: 316 SQNEVELGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTK 375
           S      GELLLSL Y PSA  + V++I+A+ L   D+   SDP+VK+ L++  K V+ K
Sbjct: 261 SDGSGSRGELLLSLCYNPSANSIIVNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKK 320

Query: 376 KTSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSNDFIGRIVIGQYSSGPS 435
           KT  ++  ++P +NESF+F +P E+L   +++ TV   +  S ND IG+I +  + SGP 
Sbjct: 321 KTVTMKRNLNPIFNESFAFDIPTEKLRETTIIITVMDKDKLSRNDVIGKIYL-SWKSGPG 379

Query: 436 ETNHWRRMLNTHRTAVEQWHSLRS 459
           E  HW+ M+   R  V QWH L++
Sbjct: 380 EVKHWKDMIARPRQPVAQWHQLKA 403


>gi|92859638 synaptotagmin V [Homo sapiens]
          Length = 386

 Score =  209 bits (532), Expect = 4e-54
 Identities = 114/307 (37%), Positives = 181/307 (58%), Gaps = 13/307 (4%)

Query: 153 YFRKFEPHLYSLDSNSDDVDSLTDEEILSKYQLGMLHFSTQYDLLHNHLTVRVIEARDLP 212
           Y  K +P +  L+       S   +++  K++LG L +S  YD     L V +++A  L 
Sbjct: 81  YIDKVQPEVEELEP----APSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLA 136

Query: 213 PPISHDGSRQDMAHSNPYVKICLLPDQKNSKQTGVKRKTQKPVFEERYTFEIPFLEAQRR 272
             +   GS      S+PYV++ LLPD++   +T V R+T  P F E + F++P++E   R
Sbjct: 137 A-LDLGGS------SDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFKVPYVELGGR 189

Query: 273 TLLLTVVDFDKFSRHCVIGKVSVPLCEVDLVKGGHWWKALIPSSQNEVE-LGELLLSLNY 331
            L++ V DFD+FSR+  IG+V VP+  VDL +    W+ L  + + E E LG++  SL Y
Sbjct: 190 VLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKLGDICFSLRY 249

Query: 332 LPSAGRLNVDVIRAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNES 391
           +P+AG+L V V+ AK L + DV   SDP+VK+ L+ G K V+ KKT+  + T++P+YNE+
Sbjct: 250 VPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEA 309

Query: 392 FSFKVPQEELENASLVFTVFGHNMKSSNDFIGRIVIGQYSSGPSETNHWRRMLNTHRTAV 451
           FSF+VP ++++   +  TV  ++    N+ IGR+ +G  ++G +   HW  ML   R  +
Sbjct: 310 FSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGA-AAGGAGLRHWADMLANPRRPI 368

Query: 452 EQWHSLR 458
            QWHSLR
Sbjct: 369 AQWHSLR 375


>gi|45504376 synaptotagmin VI [Homo sapiens]
          Length = 425

 Score =  189 bits (481), Expect = 4e-48
 Identities = 112/304 (36%), Positives = 171/304 (56%), Gaps = 15/304 (4%)

Query: 156 KFEPHLYSLDSNSDDVDSLTDEEILSKYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPI 215
           + +P LY   S   +     D +  +    G ++FS +YD     L VR+++A DLP   
Sbjct: 121 RIKPELYKQKSVDGE-----DAKSEATKSCGKINFSLRYDYETETLIVRILKAFDLP--- 172

Query: 216 SHDGSRQDMAHSNPYVKICLLPDQKNSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLL 275
               ++     S+PYVKI LLPD+K   QT V RKT  P F+E + F +P+ E   R L 
Sbjct: 173 ----AKDFCGSSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLH 228

Query: 276 LTVVDFDKFSRHCVIGKVSVP-LCEV-DLVKGGHWWKALIPSSQNEVELGELLLSLNYLP 333
           L+V DFD+FSRH +IG+V +  L E  DL +    WK +  ++   V+LGE++ SL YLP
Sbjct: 229 LSVFDFDRFSRHDMIGEVILDNLFEASDLSRETSIWKDIQYATSESVDLGEIMFSLCYLP 288

Query: 334 SAGRLNVDVIRAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFS 393
           +AGRL + VI+ + L   D++  SDP+VK+ L+   + +K KKT+  + T++P YNE+  
Sbjct: 289 TAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAII 348

Query: 394 FKVPQEELENASLVFTVFGHNMKSSNDFIGRIVIGQYSSGPSETNHWRRMLNTHRTAVEQ 453
           F +P E ++  SL+ +V  ++    N+ IG   +G  + G    +HW  ML   R  +  
Sbjct: 349 FDIPPENMDQVSLLISVMDYDRVGHNEIIGVCRVGITAEGLGR-DHWNEMLAYPRKPIAH 407

Query: 454 WHSL 457
           WHSL
Sbjct: 408 WHSL 411


>gi|28376627 synaptotagmin IX [Homo sapiens]
          Length = 491

 Score =  186 bits (472), Expect = 4e-47
 Identities = 126/393 (32%), Positives = 201/393 (51%), Gaps = 46/393 (11%)

Query: 75  HTASEVPLTPRTNSPDG--------RRSSSDTSKSTYSLTRRISSLESRRPSSPLIDIKP 126
           HT+ ++PL+ +T   +         R+ +  TS + ++  RR  +L     S+P  +I+ 
Sbjct: 131 HTSPDIPLSTQTGIQENCAHGVRVQRQVTEPTSSARHNSIRRQLNL-----SNPDFNIQQ 185

Query: 127 IEFGVLSAKKEPIQPSVLRRTYNPDDYFRKFEPHLYSLDSNSDDVDSLTDEEILSKYQLG 186
           ++      K+E +                + +P LY   S  +D     D    +    G
Sbjct: 186 LQ------KQEQLTG------------IGRIKPELYKQRSLDND-----DGRRSNSKACG 222

Query: 187 MLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLLPDQKNSKQTG 246
            L+F  +YD     L V++ +A +LP       ++     S+PYVKI LLPD+K   QT 
Sbjct: 223 KLNFILKYDCDLEQLIVKIHKAVNLP-------AKDFSGTSDPYVKIYLLPDRKTKHQTK 275

Query: 247 VKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSVP--LCEVDLVK 304
           V RKT  PVF+E + F +P+ + + R L  +V DFD+FSRH +IG+V V   L   D  +
Sbjct: 276 VHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPR 335

Query: 305 GGHWWKALIPSSQNEVELGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGSDPFVKIQ 364
               WK +   + + V+LGEL+ SL YLP+AGRL + +I+A+ L   D++  SDP+VK+ 
Sbjct: 336 ECILWKDIEYVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVS 395

Query: 365 LVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSNDFIGR 424
           L+   + +K +KTS  R T++P YNE+  F VP E ++   L   V  ++    N+ IG 
Sbjct: 396 LMCDGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGV 455

Query: 425 IVIGQYSSGPSETNHWRRMLNTHRTAVEQWHSL 457
             +G  +      +HW  ML+  R  +  WHSL
Sbjct: 456 CQVGNEAERLGR-DHWSEMLSYPRKPIAHWHSL 487


>gi|39752671 synaptotagmin X [Homo sapiens]
          Length = 523

 Score =  186 bits (471), Expect = 5e-47
 Identities = 108/304 (35%), Positives = 170/304 (55%), Gaps = 15/304 (4%)

Query: 156 KFEPHLYSLDSNSDDVDSLTDEEILSKYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPI 215
           + +P LY   S   + +   D +I  K     L+F+ QYD  +  L V++I+A DLP   
Sbjct: 208 RIKPELYKQKSVDSEGNQNEDVKICGK-----LNFTLQYDYENELLVVKIIKALDLP--- 259

Query: 216 SHDGSRQDMAHSNPYVKICLLPDQKNSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLL 275
               ++     S+PYVK+ LLPD+K   QT V RKT  P+F+E + F + + +   R L 
Sbjct: 260 ----AKDFTGTSDPYVKMYLLPDRKKKFQTRVHRKTLNPLFDETFQFPVAYDQLSNRKLH 315

Query: 276 LTVVDFDKFSRHCVIGKVSVP-LCEV-DLVKGGHWWKALIPSSQNEVELGELLLSLNYLP 333
            +V DFD+FSRH +IG+V +  L EV DL +    WK +  ++   ++LGE++ SL YLP
Sbjct: 316 FSVYDFDRFSRHDMIGEVILDNLFEVSDLSREATVWKDIHCATTESIDLGEIMFSLCYLP 375

Query: 334 SAGRLNVDVIRAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFS 393
           +AGR+ + VI+ + L   D++  SDP+VK+ L+   + +K +KT+  + T++P YNE+  
Sbjct: 376 TAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAII 435

Query: 394 FKVPQEELENASLVFTVFGHNMKSSNDFIGRIVIGQYSSGPSETNHWRRMLNTHRTAVEQ 453
           F +P E ++  SL   V  ++    N+ IG    G  + G    +HW  ML  HR  +  
Sbjct: 436 FDIPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLDAEGLGR-DHWNEMLAYHRKPITH 494

Query: 454 WHSL 457
           WH L
Sbjct: 495 WHPL 498


>gi|238550198 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  184 bits (468), Expect = 1e-46
 Identities = 105/274 (38%), Positives = 152/274 (55%), Gaps = 9/274 (3%)

Query: 186 GMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLLPDQKNSKQT 245
           G + F+ +Y    + L VR+++A DLP       ++     S+PYVKI LLPD+K   QT
Sbjct: 301 GRISFALRYLYGSDQLVVRILQALDLP-------AKDSNGFSDPYVKIYLLPDRKKKFQT 353

Query: 246 GVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSVP-LCEV-DLV 303
            V RKT  PVF E + F +P  E  +R L  +V DFD+FSRH +IG+V +  L E+ +  
Sbjct: 354 KVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQP 413

Query: 304 KGGHWWKALIPSSQNEVELGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGSDPFVKI 363
                W+ ++     + +LGEL  SL YLP+AGRL V +I+A  L   D++  SDP+VK 
Sbjct: 414 PDRPLWRDIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKA 473

Query: 364 QLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSNDFIG 423
            L+   + +K +KTS  + T++P YNE+  F V  E +EN  L   V  ++    N+ IG
Sbjct: 474 SLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIG 533

Query: 424 RIVIGQYSSGPSETNHWRRMLNTHRTAVEQWHSL 457
              +G  ++ P    HW  ML   R  VE WH L
Sbjct: 534 VCRVGPDAADPHGREHWAEMLANPRKPVEHWHQL 567



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 39/133 (29%), Positives = 59/133 (44%), Gaps = 9/133 (6%)

Query: 182 KYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLLPDQKN 241
           K  LG L+FS  Y      LTV +I+A +L        +      S+PYVK  L+ + + 
Sbjct: 429 KADLGELNFSLCYLPTAGRLTVTIIKASNLK-------AMDLTGFSDPYVKASLISEGRR 481

Query: 242 SK--QTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSVPLCE 299
            K  +T +K+ T  P + E   F++     +   L + VVD+D    + VIG   V    
Sbjct: 482 LKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDA 541

Query: 300 VDLVKGGHWWKAL 312
            D     HW + L
Sbjct: 542 ADPHGREHWAEML 554


>gi|238550196 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  184 bits (468), Expect = 1e-46
 Identities = 105/274 (38%), Positives = 152/274 (55%), Gaps = 9/274 (3%)

Query: 186 GMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLLPDQKNSKQT 245
           G + F+ +Y    + L VR+++A DLP       ++     S+PYVKI LLPD+K   QT
Sbjct: 301 GRISFALRYLYGSDQLVVRILQALDLP-------AKDSNGFSDPYVKIYLLPDRKKKFQT 353

Query: 246 GVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSVP-LCEV-DLV 303
            V RKT  PVF E + F +P  E  +R L  +V DFD+FSRH +IG+V +  L E+ +  
Sbjct: 354 KVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQP 413

Query: 304 KGGHWWKALIPSSQNEVELGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGSDPFVKI 363
                W+ ++     + +LGEL  SL YLP+AGRL V +I+A  L   D++  SDP+VK 
Sbjct: 414 PDRPLWRDIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKA 473

Query: 364 QLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSNDFIG 423
            L+   + +K +KTS  + T++P YNE+  F V  E +EN  L   V  ++    N+ IG
Sbjct: 474 SLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIG 533

Query: 424 RIVIGQYSSGPSETNHWRRMLNTHRTAVEQWHSL 457
              +G  ++ P    HW  ML   R  VE WH L
Sbjct: 534 VCRVGPDAADPHGREHWAEMLANPRKPVEHWHQL 567



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 39/133 (29%), Positives = 59/133 (44%), Gaps = 9/133 (6%)

Query: 182 KYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLLPDQKN 241
           K  LG L+FS  Y      LTV +I+A +L        +      S+PYVK  L+ + + 
Sbjct: 429 KADLGELNFSLCYLPTAGRLTVTIIKASNLK-------AMDLTGFSDPYVKASLISEGRR 481

Query: 242 SK--QTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSVPLCE 299
            K  +T +K+ T  P + E   F++     +   L + VVD+D    + VIG   V    
Sbjct: 482 LKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDA 541

Query: 300 VDLVKGGHWWKAL 312
            D     HW + L
Sbjct: 542 ADPHGREHWAEML 554


>gi|14150054 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  184 bits (468), Expect = 1e-46
 Identities = 105/274 (38%), Positives = 152/274 (55%), Gaps = 9/274 (3%)

Query: 186 GMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLLPDQKNSKQT 245
           G + F+ +Y    + L VR+++A DLP       ++     S+PYVKI LLPD+K   QT
Sbjct: 301 GRISFALRYLYGSDQLVVRILQALDLP-------AKDSNGFSDPYVKIYLLPDRKKKFQT 353

Query: 246 GVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSVP-LCEV-DLV 303
            V RKT  PVF E + F +P  E  +R L  +V DFD+FSRH +IG+V +  L E+ +  
Sbjct: 354 KVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQP 413

Query: 304 KGGHWWKALIPSSQNEVELGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGSDPFVKI 363
                W+ ++     + +LGEL  SL YLP+AGRL V +I+A  L   D++  SDP+VK 
Sbjct: 414 PDRPLWRDIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKA 473

Query: 364 QLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSNDFIG 423
            L+   + +K +KTS  + T++P YNE+  F V  E +EN  L   V  ++    N+ IG
Sbjct: 474 SLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIG 533

Query: 424 RIVIGQYSSGPSETNHWRRMLNTHRTAVEQWHSL 457
              +G  ++ P    HW  ML   R  VE WH L
Sbjct: 534 VCRVGPDAADPHGREHWAEMLANPRKPVEHWHQL 567



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 39/133 (29%), Positives = 59/133 (44%), Gaps = 9/133 (6%)

Query: 182 KYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLLPDQKN 241
           K  LG L+FS  Y      LTV +I+A +L        +      S+PYVK  L+ + + 
Sbjct: 429 KADLGELNFSLCYLPTAGRLTVTIIKASNLK-------AMDLTGFSDPYVKASLISEGRR 481

Query: 242 SK--QTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSVPLCE 299
            K  +T +K+ T  P + E   F++     +   L + VVD+D    + VIG   V    
Sbjct: 482 LKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDA 541

Query: 300 VDLVKGGHWWKAL 312
            D     HW + L
Sbjct: 542 ADPHGREHWAEML 554


>gi|216548478 synaptotagmin XI [Homo sapiens]
          Length = 431

 Score =  174 bits (441), Expect = 2e-43
 Identities = 116/337 (34%), Positives = 182/337 (54%), Gaps = 15/337 (4%)

Query: 128 EFGVLSAKKEPIQPS---VLRRTYNPDDYFRKFEPHLYSLDSNSDDVDSLTDEEILSKYQ 184
           E G+LS  K+P  PS    + +     DY  +    + SL        S +  E      
Sbjct: 100 EAGLLSRDKDPRGPSSGSCIDQLPIKMDYGEELRSPITSLTPGESKTTSPSSPE--EDVM 157

Query: 185 LGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLLPDQKNSKQ 244
           LG L FS  Y+     L V + EA  LP  +  D ++     S+PY+K+ +LPD+++  +
Sbjct: 158 LGSLTFSVDYNFPKKALVVTIQEAHGLP--VMDDQTQG----SDPYIKMTILPDKRHRVK 211

Query: 245 TGVKRKTQKPVFEERYTFE-IPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSVPLCEVDLV 303
           T V RKT  PVF+E +TF  IP+ + Q   L   V+ FD+FSR  VIG+V VPL  VD  
Sbjct: 212 TRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGVDPS 271

Query: 304 KGG-HWWKALIPSS-QNEVELGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGS-DPF 360
            G     + +I  + Q  +  GEL +SL+Y P A R+ V V++A+ L + D++  S +P+
Sbjct: 272 TGKVQLTRDIIKRNIQKCISRGELQVSLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPY 331

Query: 361 VKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSND 420
           VK+ + +G K +  KKT   + T++P +NESF + +P + L + S+ F V   +  + N+
Sbjct: 332 VKVNVYYGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNE 391

Query: 421 FIGRIVIGQYSSGPSETNHWRRMLNTHRTAVEQWHSL 457
            +GR+++G +S   S   HWR +  + R  V +WHSL
Sbjct: 392 VVGRLILGAHSVTASGAEHWREVCESPRKPVAKWHSL 428


>gi|24308219 synaptotagmin IV [Homo sapiens]
          Length = 425

 Score =  168 bits (425), Expect = 1e-41
 Identities = 106/288 (36%), Positives = 159/288 (55%), Gaps = 12/288 (4%)

Query: 173 SLTDEEILSKYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVK 232
           SLT EE   K  LG L FS +Y+       V + EAR LP         Q M  S+PY+K
Sbjct: 144 SLTSEEKQEK--LGTLFFSLEYNFERKAFVVNIKEARGLPAM-----DEQSMT-SDPYIK 195

Query: 233 ICLLPDQKNSKQTGVKRKTQKPVFEERYTFE-IPFLEAQRRTLLLTVVDFDKFSRHCVIG 291
           + +LP++K+  +T V RKT  P F+E +TF  IP+ + Q   L  T++ FD+FSR  +IG
Sbjct: 196 MTILPEKKHKVKTRVLRKTLDPAFDETFTFYGIPYTQIQELALHFTILSFDRFSRDDIIG 255

Query: 292 KVSVPLCEVDLVKGGHWWKALI--PSSQNEVELGELLLSLNYLPSAGRLNVDVIRAKQLL 349
           +V +PL  ++L +G       I   + +     GELL+SL Y  +   L V V++A+ L 
Sbjct: 256 EVLIPLSGIELSEGKMLMNREIIKRNVRKSSGRGELLISLCYQSTTNTLTVVVLKARHLP 315

Query: 350 QTDVSQGSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVFT 409
           ++DVS  SDP+VK+ L H  K +  KKT   + T +  +NE F F +P E LE+ S+ F 
Sbjct: 316 KSDVSGLSDPYVKVNLYHAKKRISKKKTHVKKCTPNAVFNELFVFDIPCEGLEDISVEFL 375

Query: 410 VFGHNMKSSNDFIGRIVIGQYSSGPSETNHWRRMLNTHRTAVEQWHSL 457
           V      S N+ IG++V+G  + G +   HW+ + +  R  + +WH L
Sbjct: 376 VLDSERGSRNEVIGQLVLGAAAEG-TGGEHWKEICDYPRRQIAKWHVL 422


>gi|31881675 synaptotagmin XV isoform a [Homo sapiens]
          Length = 421

 Score =  145 bits (366), Expect = 8e-35
 Identities = 96/277 (34%), Positives = 141/277 (50%), Gaps = 13/277 (4%)

Query: 185 LGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLLPDQKNSKQ 244
           LG L FS +Y+     L V +I+A+ L  P             +P VK+ LLPD++   Q
Sbjct: 148 LGRLWFSVEYEQEAERLLVGLIKAQHLQAPSET---------CSPLVKLYLLPDERRFLQ 198

Query: 245 TGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSVPLCEVDLVK 304
           +  KRKT  P F+E + F++      +R L  +V   D+  +H ++G+V  PL    LV 
Sbjct: 199 SKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVG 258

Query: 305 GGH---WWKALIPSSQNEVELGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGSDPFV 361
                 W      S +   E G+L   L+Y     RL V V+RAK L   +       FV
Sbjct: 259 DCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFV 318

Query: 362 KIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSNDF 421
           K+ L++  K VK KKTS + G+I+P YNE+FSFK    EL+ ASL  TV  +     +  
Sbjct: 319 KVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEGDKSQQ 378

Query: 422 IGRIVIGQYS-SGPSETNHWRRMLNTHRTAVEQWHSL 457
           +GR+V+G Y  +   E  HW  ML+  +  V++WH+L
Sbjct: 379 LGRVVVGPYMYTRGRELEHWDEMLSKPKELVKRWHAL 415


>gi|94536846 synaptotagmin VIII [Homo sapiens]
          Length = 401

 Score =  143 bits (361), Expect = 3e-34
 Identities = 96/298 (32%), Positives = 153/298 (51%), Gaps = 17/298 (5%)

Query: 170 DVDSLTDEEILSKYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNP 229
           DVD L +       Q G L  S ++D     + V + +A DL P  + D          P
Sbjct: 104 DVDGL-ESSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRPGGTVD----------P 152

Query: 230 YVKICLLPDQKNSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHCV 289
           Y ++ +     +  +T V R T  PVF+E   F IP  E    TL + + +F +FS H  
Sbjct: 153 YARVSVSTQAGHRHETKVHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEP 212

Query: 290 IGKVSVPLCEVDLVKG-GHWWKALIPSSQNEVELGELLLSLNYLPSAGRLNVDVIRAKQL 348
           +G++ +PL  VDL     HW+    P++    ++GEL  SL Y+PS+GRL V V+ A+ L
Sbjct: 213 LGELRLPLGTVDLQHVLEHWYLLGPPAATQPEQVGELCFSLRYVPSSGRLTVVVLEARGL 272

Query: 349 LQTDVSQGSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVF 408
                   ++P+VK+QL+   +  K +KT+  +GT  P++NE+F+F VP  +++N  LV 
Sbjct: 273 RPGL----AEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVL 328

Query: 409 TVFGHNMKSSNDFIGRIVIGQYSSGPSETNHWRRMLNTHRTAVEQWHSLRSRAECDRV 466
            V+  ++    + +G++ +G  +SG     HW  ML   R  + Q H LR   E DR+
Sbjct: 329 AVWDRSLPLRTEPVGKVHLGARASG-QPLQHWADMLAHARRPIAQRHPLRPAREVDRM 385


>gi|29366828 synaptotagmin XII [Homo sapiens]
          Length = 421

 Score =  142 bits (357), Expect = 9e-34
 Identities = 91/303 (30%), Positives = 156/303 (51%), Gaps = 14/303 (4%)

Query: 162 YSLDSNSDDVDSLTDEEILSK-----YQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPIS 216
           Y     S   DSL     +S      + LG +  S +YD   + L V V++ +DL     
Sbjct: 125 YGTLRKSQSADSLNSISSVSNTFGQDFTLGQVEVSMEYDTASHTLNVAVMQGKDLL---- 180

Query: 217 HDGSRQDMAHSNPYVKICLLPDQKNSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLL 276
               R++ +  + ++++ LLPD++    + ++R      F+E+++  +     + ++L  
Sbjct: 181 ---EREEASFESCFMRVSLLPDEQIVGISRIQRNAYSIFFDEKFSIPLDPTALEEKSLRF 237

Query: 277 TVVDFDKFSRHCVIGKVSVPLCEVDL-VKGGHWWKALIPSSQNEVELGELLLSLNYLPSA 335
           +V   D+  R+   G V + L  +DL ++    W  L   ++    +GE+LLSL+YLP+A
Sbjct: 238 SVFGIDEDERNVSTGVVELKLSVLDLPLQPFSGWLYLQDQNKAADAVGEILLSLSYLPTA 297

Query: 336 GRLNVDVIRAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFK 395
            RL V V++AK L+ T+    +DPFVK+ L+   + +  KKT+  R   +P +NE+  F 
Sbjct: 298 ERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDGRKMSKKKTAVKRDDPNPVFNEAMIFS 357

Query: 396 VPQEELENASLVFTVFGHNMKSSNDFIGRIVIGQYSSGPSETNHWRRMLNTHRTAVEQWH 455
           VP   L++ SL  TV   +     D +G ++IG  +SG   T HW +ML T R  V  WH
Sbjct: 358 VPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIGPSASGMG-TTHWNQMLATLRRPVSMWH 416

Query: 456 SLR 458
           ++R
Sbjct: 417 AVR 419


>gi|6005997 double C2-like domains, beta [Homo sapiens]
          Length = 412

 Score =  125 bits (313), Expect = 1e-28
 Identities = 92/288 (31%), Positives = 143/288 (49%), Gaps = 24/288 (8%)

Query: 185 LGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLLP--DQKNS 242
           LG L FS  YD  +N L   + +A+ L P + H+G       ++PYVK+ LLP   + N 
Sbjct: 127 LGTLDFSLLYDQENNALHCTITKAKGLKP-MDHNGL------ADPYVKLHLLPGASKANK 179

Query: 243 KQTGVKRKTQKPVFEERYTFE-IPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSVPLCEVD 301
            +T   R T  P + E  T+  I   +  R+TL ++V D DKF  +  IG+  VPL ++ 
Sbjct: 180 LRTKTLRNTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGETRVPLKKL- 238

Query: 302 LVKGGHW------WKALIPSSQNE----VELGELLLSLNYLPSAGRLNVDVIRAKQLLQT 351
             K  H        +  +P  + E     E G +L+SL Y      L V ++R   L   
Sbjct: 239 --KPNHTKTFNICLEKQLPVDKTEDKSLEERGRILISLKYSSQKQGLLVGIVRCAHLAAM 296

Query: 352 DVSQGSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVFTVF 411
           D +  SDP+VK  L   +      KT+  + T++P +NE F +++   +L   SL  TV+
Sbjct: 297 DANGYSDPYVKTYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYEIKHGDLAKKSLEVTVW 356

Query: 412 GHNMKSSNDFIGRIVIGQYSSGPSETNHWRRMLNTHRTAVEQWHSLRS 459
            +++  SNDFIG +V+G ++ G     HW   L      +E+WH+L S
Sbjct: 357 DYDIGKSNDFIGGVVLGIHAKG-ERLKHWFDCLKNKDKRIERWHTLTS 403


>gi|31881667 synaptotagmin XV isoform b [Homo sapiens]
          Length = 390

 Score =  120 bits (300), Expect = 4e-27
 Identities = 82/229 (35%), Positives = 116/229 (50%), Gaps = 12/229 (5%)

Query: 185 LGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLLPDQKNSKQ 244
           LG L FS +Y+     L V +I+A+ L  P             +P VK+ LLPD++   Q
Sbjct: 148 LGRLWFSVEYEQEAERLLVGLIKAQHLQAPSET---------CSPLVKLYLLPDERRFLQ 198

Query: 245 TGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSVPLCEVDLVK 304
           +  KRKT  P F+E + F++      +R L  +V   D+  +H ++G+V  PL    LV 
Sbjct: 199 SKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVG 258

Query: 305 GGH---WWKALIPSSQNEVELGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGSDPFV 361
                 W      S +   E G+L   L+Y     RL V V+RAK L   +       FV
Sbjct: 259 DCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFV 318

Query: 362 KIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVFTV 410
           K+ L++  K VK KKTS + G+I+P YNE+FSFK    EL+ ASL  TV
Sbjct: 319 KVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTV 367



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 30/105 (28%), Positives = 53/105 (50%), Gaps = 4/105 (3%)

Query: 322 LGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTKKTSFLR 381
           LG L  S+ Y   A RL V +I+A+ L     S+   P VK+ L+   +     KT   R
Sbjct: 148 LGRLWFSVEYEQEAERLLVGLIKAQHLQAP--SETCSPLVKLYLLPDERRFLQSKTK--R 203

Query: 382 GTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSNDFIGRIV 426
            T +P ++E F F+V  + +    L F+V+  + +  +  +G+++
Sbjct: 204 KTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVL 248



 Score = 34.3 bits (77), Expect = 0.25
 Identities = 29/108 (26%), Positives = 48/108 (44%), Gaps = 9/108 (8%)

Query: 174 LTDEEILSKYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKI 233
           L  E +    + G L F   Y+   + LTV V+ A+ L         ++D    + +VK+
Sbjct: 268 LEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLR-------LQEDRGIVSVFVKV 320

Query: 234 CLLPDQK--NSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVV 279
            L+   K    K+T     +  PV+ E ++F+    E    +L LTVV
Sbjct: 321 SLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVV 368


>gi|24308233 synaptotagmin XIII [Homo sapiens]
          Length = 426

 Score =  119 bits (299), Expect = 5e-27
 Identities = 111/405 (27%), Positives = 177/405 (43%), Gaps = 34/405 (8%)

Query: 75  HTASEVPLTPRTNSPD---------GRRSSSDTSKSTYSLTRR----ISSLESRRPSSPL 121
           H   +  L PR   PD         G     +  KST  +  R       +   RP+   
Sbjct: 32  HMHPKKGLLPRDQDPDLEKAKPSLLGSAQQFNVKKSTEPVQPRALLKFPDIYGPRPAVTA 91

Query: 122 IDIKPIEFGVLSAKKEPIQPSVLRRTYNPDDYFRKFEPHLYSLDSNS--DDV---DSLTD 176
            ++       L + +EP  P+  +   N     R+    L+ L  N   +DV   ++   
Sbjct: 92  PEVINYADYSLRSTEEPTAPASPQPP-NDSRLKRQVTEELFILPQNGVVEDVCVMETWNP 150

Query: 177 EEILSKYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLL 236
           E+  S  Q   LH+   YD     L V  +EA       +HDG        + YV+  + 
Sbjct: 151 EKAASWNQAPKLHYCLDYDCQKAELFVTRLEA----VTSNHDGG------CDCYVQGSVA 200

Query: 237 PDQKNSK-QTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSV 295
               + + QT +K++     +EE     +   E    TL LT+   D+FSRH V G++ +
Sbjct: 201 NRTGSVEAQTALKKRQLHTTWEEGLVLPLAEEELPTATLTLTLRTCDRFSRHSVAGELRL 260

Query: 296 PLCEVDLVKGGHWWKALIPSSQN-EVELGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVS 354
            L    +  G   W  L  S++      GE+LLS++YLP+A RL V +I+AK L      
Sbjct: 261 GLDGTSVPLGAAQWGELKTSAKEPSAGAGEVLLSISYLPAANRLLVVLIKAKNLHSNQSK 320

Query: 355 Q--GSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFG 412
           +  G D  VK+ L H  + +K K+T   +  I+P +NE   F++P + L+ +S+   V G
Sbjct: 321 ELLGKDVSVKVTLKHQARKLKKKQTKRAKHKINPVWNEMIMFELPDDLLQASSVELEVLG 380

Query: 413 HNMKSSNDFIGRIVIGQYSSGPSETNHWRRMLNTHRTAVEQWHSL 457
            +    +  +G   +G ++SG SE +HW  ML   R  +  WH L
Sbjct: 381 QDDSGQSCALGHCSLGLHTSG-SERSHWEEMLKNPRRQIAMWHQL 424


>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
          Length = 694

 Score =  116 bits (290), Expect = 5e-26
 Identities = 94/323 (29%), Positives = 145/323 (44%), Gaps = 44/323 (13%)

Query: 165 DSNSDDVDSLTDEEILSKYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDM 224
           ++NS D D  T         LG L FS  YD  ++ L   +I+A+ L P  S+       
Sbjct: 381 EANSYDSDEATT--------LGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSN------- 425

Query: 225 AHSNPYVKICLLP--DQKNSKQTGVKRKTQKPVFEERYTFE-IPFLEAQRRTLLLTVVDF 281
             ++PYVK+ LLP   + N  +T   R T+ P++ E   +  I   + QR+TL ++V D 
Sbjct: 426 GLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDE 485

Query: 282 DKFSRHCVIGKVSVPLCEVDL--------------------VKGGHWWKALIPSSQNE-- 319
           DKF  +  IG+    L ++                        G     AL    Q E  
Sbjct: 486 DKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERV 545

Query: 320 ---VELGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTKK 376
               E G++L+SL Y    G L V +IR   L   D +  SDPFVK+ L   +      K
Sbjct: 546 GDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHK 605

Query: 377 TSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSNDFIGRIVIGQYSSGPSE 436
           T   + T++P +NE F + +   +L   SL  +V+ +++  SND+IG   +G  + G   
Sbjct: 606 TQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKG-ER 664

Query: 437 TNHWRRMLNTHRTAVEQWHSLRS 459
             HW   L      +E+WH L++
Sbjct: 665 LKHWYECLKNKDKKIERWHQLQN 687



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 31/115 (26%), Positives = 61/115 (53%), Gaps = 12/115 (10%)

Query: 226 HSNPYVKICLLPD--QKNSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDK 283
           +S+P+VK+ L PD  +K   +T +K+KT  P F E + ++I   +  +++L ++V D+D 
Sbjct: 585 YSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDI 644

Query: 284 FSRHCVIGKVSVPLCEVDLVKGG----HWWKALIPSSQNEVELGELLLSLNYLPS 334
              +  IG      C++ +   G    HW++ L  +   ++E    L + N++ S
Sbjct: 645 GKSNDYIGG-----CQLGISAKGERLKHWYECL-KNKDKKIERWHQLQNENHVSS 693


>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
          Length = 690

 Score =  116 bits (290), Expect = 5e-26
 Identities = 94/323 (29%), Positives = 145/323 (44%), Gaps = 44/323 (13%)

Query: 165 DSNSDDVDSLTDEEILSKYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDM 224
           ++NS D D  T         LG L FS  YD  ++ L   +I+A+ L P  S+       
Sbjct: 377 EANSYDSDEATT--------LGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSN------- 421

Query: 225 AHSNPYVKICLLP--DQKNSKQTGVKRKTQKPVFEERYTFE-IPFLEAQRRTLLLTVVDF 281
             ++PYVK+ LLP   + N  +T   R T+ P++ E   +  I   + QR+TL ++V D 
Sbjct: 422 GLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDE 481

Query: 282 DKFSRHCVIGKVSVPLCEVDL--------------------VKGGHWWKALIPSSQNE-- 319
           DKF  +  IG+    L ++                        G     AL    Q E  
Sbjct: 482 DKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERV 541

Query: 320 ---VELGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTKK 376
               E G++L+SL Y    G L V +IR   L   D +  SDPFVK+ L   +      K
Sbjct: 542 GDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHK 601

Query: 377 TSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSNDFIGRIVIGQYSSGPSE 436
           T   + T++P +NE F + +   +L   SL  +V+ +++  SND+IG   +G  + G   
Sbjct: 602 TQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKG-ER 660

Query: 437 TNHWRRMLNTHRTAVEQWHSLRS 459
             HW   L      +E+WH L++
Sbjct: 661 LKHWYECLKNKDKKIERWHQLQN 683



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 31/115 (26%), Positives = 61/115 (53%), Gaps = 12/115 (10%)

Query: 226 HSNPYVKICLLPD--QKNSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDK 283
           +S+P+VK+ L PD  +K   +T +K+KT  P F E + ++I   +  +++L ++V D+D 
Sbjct: 581 YSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDI 640

Query: 284 FSRHCVIGKVSVPLCEVDLVKGG----HWWKALIPSSQNEVELGELLLSLNYLPS 334
              +  IG      C++ +   G    HW++ L  +   ++E    L + N++ S
Sbjct: 641 GKSNDYIGG-----CQLGISAKGERLKHWYECL-KNKDKKIERWHQLQNENHVSS 689


>gi|47078261 double C2-like domains, alpha [Homo sapiens]
          Length = 400

 Score =  110 bits (275), Expect = 3e-24
 Identities = 93/322 (28%), Positives = 146/322 (45%), Gaps = 43/322 (13%)

Query: 170 DVDSLTDEEILSKYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNP 229
           +VDS   ++  +   LG L F   YD     L   ++ A+ L P +  +G       ++P
Sbjct: 78  EVDSYDSDDATA---LGTLEFDLLYDRASCTLHCSILRAKGLKP-MDFNGL------ADP 127

Query: 230 YVKICLLPD--QKNSKQTGVKRKTQKPVFEERYTFE-IPFLEAQRRTLLLTVVDFDKFSR 286
           YVK+ LLP   + N  +T  +R T  PV+ E  T+  I   +   + L + V D DK S 
Sbjct: 128 YVKLHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSH 187

Query: 287 HCVIGKVSVPLCEVDLVKGGHWWKAL-------IPSSQNEV------------------- 320
           +  IG++ VPL  +   +  H+   L        PSS +                     
Sbjct: 188 NEFIGEIRVPLRRLKPSQKKHFNICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQG 247

Query: 321 ---ELGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTKKT 377
              E G +LLSL+Y      L V ++R   L   DV+  SDP+VK  L   +      KT
Sbjct: 248 LLEERGRILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKT 307

Query: 378 SFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSNDFIGRIVIGQYSSGPSET 437
              + T++P +NE F +++    L   +L  TV+ +++  SNDFIG + +G  + G +  
Sbjct: 308 CVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEAR- 366

Query: 438 NHWRRMLNTHRTAVEQWHSLRS 459
            HW   L     A+E+WH+L S
Sbjct: 367 KHWSDCLQQPDAALERWHTLTS 388


>gi|193804862 synaptotagmin-like 4 [Homo sapiens]
          Length = 671

 Score = 95.9 bits (237), Expect = 7e-20
 Identities = 78/271 (28%), Positives = 127/271 (46%), Gaps = 37/271 (13%)

Query: 186 GMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLLPDQ--KNSK 243
           G + FS +Y+     L V V E   L        + +    SNPYVK  LLPD+  +  +
Sbjct: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAY------ADEAKKRSNPYVKTYLLPDKSRQGKR 411

Query: 244 QTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSVPLCEVDLV 303
           +T +KR T  P+++E   +EIP     +RTL  +V    +F R+  +G+  +   ++D  
Sbjct: 412 KTSIKRDTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEI---QMDSW 468

Query: 304 KGGHWWKALIP-----SSQNEVEL----GELLLSLNYLPSA----------------GRL 338
           K        +P     S+++   L    GEL++SL Y+P++                G L
Sbjct: 469 KLDKKLDHCLPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGEL 528

Query: 339 NVDVIRAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFK-VP 397
            V +  AK L        SD FVK  L+        +KT  ++ T++P YN +F +  V 
Sbjct: 529 QVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVR 588

Query: 398 QEELENASLVFTVFGHNMKSSNDFIGRIVIG 428
            E+L++  L  TV+     +SNDF+G + +G
Sbjct: 589 LEDLQHMCLELTVWDREPLASNDFLGGVRLG 619


>gi|193804860 synaptotagmin-like 4 [Homo sapiens]
          Length = 671

 Score = 95.9 bits (237), Expect = 7e-20
 Identities = 78/271 (28%), Positives = 127/271 (46%), Gaps = 37/271 (13%)

Query: 186 GMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLLPDQ--KNSK 243
           G + FS +Y+     L V V E   L        + +    SNPYVK  LLPD+  +  +
Sbjct: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAY------ADEAKKRSNPYVKTYLLPDKSRQGKR 411

Query: 244 QTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSVPLCEVDLV 303
           +T +KR T  P+++E   +EIP     +RTL  +V    +F R+  +G+  +   ++D  
Sbjct: 412 KTSIKRDTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEI---QMDSW 468

Query: 304 KGGHWWKALIP-----SSQNEVEL----GELLLSLNYLPSA----------------GRL 338
           K        +P     S+++   L    GEL++SL Y+P++                G L
Sbjct: 469 KLDKKLDHCLPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGEL 528

Query: 339 NVDVIRAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFK-VP 397
            V +  AK L        SD FVK  L+        +KT  ++ T++P YN +F +  V 
Sbjct: 529 QVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVR 588

Query: 398 QEELENASLVFTVFGHNMKSSNDFIGRIVIG 428
            E+L++  L  TV+     +SNDF+G + +G
Sbjct: 589 LEDLQHMCLELTVWDREPLASNDFLGGVRLG 619


>gi|239744413 PREDICTED: hypothetical protein LOC390213 [Homo
           sapiens]
          Length = 431

 Score = 95.1 bits (235), Expect = 1e-19
 Identities = 86/299 (28%), Positives = 135/299 (45%), Gaps = 35/299 (11%)

Query: 185 LGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLLPDQKNSKQ 244
           LG L F+  ++  ++ L      A+ L P  S          ++ YVK  LLP    + Q
Sbjct: 139 LGTLEFTLLFEADNSALHCTAHRAKGLKPLAS--------GSADAYVKANLLPGASKASQ 190

Query: 245 --TGVKRKTQKPVFEERYTFE-IPFLEAQRRTLLLTVVDFDKFSRHCV------------ 289
             T   R T+ PV+EE  T+      +A+ +TL     D       CV            
Sbjct: 191 LRTHTVRGTRVPVWEETLTYHGFTRQDAECKTLRS---DLGGHQAVCVRGPMVQRQWQAP 247

Query: 290 -IGKVSVPLCEVDLVKGGHWWKALIPSSQNEVEL-------GELLLSLNYLPSAGRLNVD 341
            +G++ VPL ++   +   +   L      EVE        G +LLSL Y    G L V 
Sbjct: 248 SLGELRVPLRKLVPNRARSFDICLEKRRLEEVETEVAWEECGHVLLSLCYSSQQGGLLVG 307

Query: 342 VIRAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEEL 401
           V+R   L   D +  SDPFV++ L          KTS  R T++P +NE F +  P+EEL
Sbjct: 308 VLRCAHLAPMDANGYSDPFVRLFLHPNAGKKSKFKTSVHRKTLNPEFNEEFFYSGPREEL 367

Query: 402 ENASLVFTVFGHNMKSSNDFIGRIVIGQYSSGPSETNHWRRMLNTHRTAVEQWHSLRSR 460
              +L+ +V+ +++ +++DFIG + +G ++SG     HW   L      ++ WH L S+
Sbjct: 368 AQKTLLVSVWDYDLGTADDFIGGVQLGSHASG-ERLRHWLECLGHSDHRLKLWHPLDSK 425



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 33/114 (28%), Positives = 56/114 (49%), Gaps = 9/114 (7%)

Query: 184 QLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLLPD--QKN 241
           + G +  S  Y      L V V+    L P  ++        +S+P+V++ L P+  +K+
Sbjct: 287 ECGHVLLSLCYSSQQGGLLVGVLRCAHLAPMDAN-------GYSDPFVRLFLHPNAGKKS 339

Query: 242 SKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSV 295
             +T V RKT  P F E + +  P  E  ++TLL++V D+D  +    IG V +
Sbjct: 340 KFKTSVHRKTLNPEFNEEFFYSGPREELAQKTLLVSVWDYDLGTADDFIGGVQL 393



 Score = 30.8 bits (68), Expect = 2.8
 Identities = 26/99 (26%), Positives = 44/99 (44%), Gaps = 2/99 (2%)

Query: 316 SQNEVELGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTK 375
           S +   LG L  +L +      L+    RAK L     S  +D +VK  L+ G       
Sbjct: 133 SDDSTALGTLEFTLLFEADNSALHCTAHRAKGLKPL-ASGSADAYVKANLLPGASKASQL 191

Query: 376 KTSFLRGTIDPFYNESFSFK-VPQEELENASLVFTVFGH 413
           +T  +RGT  P + E+ ++    +++ E  +L   + GH
Sbjct: 192 RTHTVRGTRVPVWEETLTYHGFTRQDAECKTLRSDLGGH 230


>gi|123173752 synaptotagmin XIV-like [Homo sapiens]
          Length = 645

 Score = 91.7 bits (226), Expect = 1e-18
 Identities = 81/306 (26%), Positives = 138/306 (45%), Gaps = 49/306 (16%)

Query: 186 GMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPY-VKICLLPDQKNSKQ 244
           G L    +Y      LTV ++ A+ LP         +D +  N + V + LLP +K+  +
Sbjct: 352 GDLDVIFEYRAASQKLTVTIVRAQGLPD--------KDRSGVNSWQVHVVLLPGKKHRGR 403

Query: 245 TGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFD-----KFSRHCVIG-------- 291
           T ++R    PVF E+ TF     + + R +    V F      K +R  ++G        
Sbjct: 404 TNIQRGPN-PVFREKVTFA----KLEPRDVAACAVRFRLYAARKMTRERMMGEKLFYLSH 458

Query: 292 -------KVSVPLCEVDLVKGGHWWKALIPSSQNEVE------------LGELLLSLNYL 332
                  KV++ L     +  G     L PS+ +  +              ELL+ L+Y 
Sbjct: 459 LHPEGEMKVTLVLEPRSNISSGG--SPLSPSAVSHSDSTSSTQSLSHGGAPELLVGLSYN 516

Query: 333 PSAGRLNVDVIRAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTK-KTSFLRGTIDPFYNES 391
            + GRL+V++I+        V++  D + K+ L++ +    ++ KTS  RG  +P Y E+
Sbjct: 517 ATTGRLSVEMIKGSHFRNLAVNRAPDTYGKLFLLNSVGQEMSRCKTSIRRGQPNPVYKET 576

Query: 392 FSFKVPQEELENASLVFTVFGHNMKSSNDFIGRIVIGQYSSGPSETNHWRRMLNTHRTAV 451
           F F+V   +L + +L+ +V+        + IG I +GQ SSG  E +HW  M  T    +
Sbjct: 577 FVFQVALFQLSDVTLMISVYNRRTMKRKEMIGWIALGQNSSGEEEQDHWEEMKETKGQQI 636

Query: 452 EQWHSL 457
            +WH+L
Sbjct: 637 CRWHTL 642



 Score = 31.2 bits (69), Expect = 2.1
 Identities = 31/140 (22%), Positives = 60/140 (42%), Gaps = 10/140 (7%)

Query: 172 DSLTDEEILSKYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYV 231
           DS +  + LS      L     Y+     L+V +I+        SH  +       + Y 
Sbjct: 493 DSTSSTQSLSHGGAPELLVGLSYNATTGRLSVEMIKG-------SHFRNLAVNRAPDTYG 545

Query: 232 KICLLPD--QKNSK-QTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHC 288
           K+ LL    Q+ S+ +T ++R    PV++E + F++   +    TL+++V +     R  
Sbjct: 546 KLFLLNSVGQEMSRCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLMISVYNRRTMKRKE 605

Query: 289 VIGKVSVPLCEVDLVKGGHW 308
           +IG +++        +  HW
Sbjct: 606 MIGWIALGQNSSGEEEQDHW 625


>gi|226342962 synaptotagmin XIV isoform 2 [Homo sapiens]
          Length = 600

 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 84/338 (24%), Positives = 142/338 (42%), Gaps = 43/338 (12%)

Query: 150 PDDYFRKFEPHLYSLDSNSDDVDSLTDEEILSKYQLGMLHFSTQYDLLHNHLTVRVIEAR 209
           P D      P   S   +S  +    D E  +KY  G L  +  YD     L V V    
Sbjct: 273 PSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAKY--GTLDVTFDYDSQEQKLLVTVTAVT 330

Query: 210 DLPPPISHDGSRQDMAHSNPYVKICLLPDQKNSKQTGVKRKTQKPVFEERYTFEIPFLEA 269
           D+P   +  G      H      + LLP +K   +T ++R    PVF E  TF+   +E+
Sbjct: 331 DIPT-YNRTGGNSWQVH------LVLLPIKKQRAKTSIQRGPC-PVFTE--TFKFNHVES 380

Query: 270 Q---RRTLLLTVVDFDKFSRHCVIGKVSVPLCEVDLVKGGHWWKALIPSSQNE------- 319
           +      +   +    +  +  ++G+    L +++L +G      ++  S N        
Sbjct: 381 EMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNL-QGKMSLPVILEPSYNHSGCDSQM 439

Query: 320 ----------------VELG---ELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGSDPF 360
                           +E G   E+L+ L Y  + GRL+ +VI+         ++  + +
Sbjct: 440 SVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTY 499

Query: 361 VKIQLVHGLKLVKTK-KTSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSN 419
           VK+ L++ +    +K KTS  RG  +P Y E+F F+V   +L + +L+ +V+        
Sbjct: 500 VKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRK 559

Query: 420 DFIGRIVIGQYSSGPSETNHWRRMLNTHRTAVEQWHSL 457
           + IG I +G  SSG  E NHW  M  +    V +WH+L
Sbjct: 560 EMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 597


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,803,475
Number of Sequences: 37866
Number of extensions: 868466
Number of successful extensions: 3356
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 76
Number of HSP's successfully gapped in prelim test: 90
Number of HSP's that attempted gapping in prelim test: 2870
Number of HSP's gapped (non-prelim): 326
length of query: 474
length of database: 18,247,518
effective HSP length: 106
effective length of query: 368
effective length of database: 14,233,722
effective search space: 5238009696
effective search space used: 5238009696
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.