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Search of human proteins with 39752671
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|39752671 synaptotagmin X [Homo sapiens]
(523 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|39752671 synaptotagmin X [Homo sapiens] 1065 0.0
gi|45504376 synaptotagmin VI [Homo sapiens] 604 e-173
gi|28376627 synaptotagmin IX [Homo sapiens] 595 e-170
gi|238550198 synaptotagmin III [Homo sapiens] 450 e-126
gi|238550196 synaptotagmin III [Homo sapiens] 450 e-126
gi|14150054 synaptotagmin III [Homo sapiens] 450 e-126
gi|209447073 synaptotagmin I [Homo sapiens] 288 6e-78
gi|5032139 synaptotagmin I [Homo sapiens] 288 6e-78
gi|209447070 synaptotagmin I [Homo sapiens] 288 6e-78
gi|211059429 synaptotagmin II [Homo sapiens] 285 7e-77
gi|31543670 synaptotagmin II [Homo sapiens] 285 7e-77
gi|92859638 synaptotagmin V [Homo sapiens] 279 5e-75
gi|38570146 synaptotagmin VII [Homo sapiens] 251 1e-66
gi|24308219 synaptotagmin IV [Homo sapiens] 224 1e-58
gi|216548478 synaptotagmin XI [Homo sapiens] 216 4e-56
gi|40068038 B/K protein [Homo sapiens] 186 6e-47
gi|94536846 synaptotagmin VIII [Homo sapiens] 171 2e-42
gi|31881675 synaptotagmin XV isoform a [Homo sapiens] 166 6e-41
gi|6005997 double C2-like domains, beta [Homo sapiens] 164 1e-40
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens] 159 5e-39
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens] 159 5e-39
gi|29366828 synaptotagmin XII [Homo sapiens] 159 8e-39
gi|31881667 synaptotagmin XV isoform b [Homo sapiens] 150 4e-36
gi|47078261 double C2-like domains, alpha [Homo sapiens] 149 5e-36
gi|24308233 synaptotagmin XIII [Homo sapiens] 134 2e-31
gi|193804862 synaptotagmin-like 4 [Homo sapiens] 125 9e-29
gi|193804860 synaptotagmin-like 4 [Homo sapiens] 125 9e-29
gi|46255062 synaptotagmin-like 2 isoform c [Homo sapiens] 115 7e-26
gi|226342962 synaptotagmin XIV isoform 2 [Homo sapiens] 115 1e-25
gi|144226225 synaptotagmin XIV isoform 4 [Homo sapiens] 115 1e-25
>gi|39752671 synaptotagmin X [Homo sapiens]
Length = 523
Score = 1065 bits (2754), Expect = 0.0
Identities = 523/523 (100%), Positives = 523/523 (100%)
Query: 1 MSFHKEDGVNSLCQKALHIVTELCFAGQVEWEKCSGIFPRDRGSQGGSSTDISVSLLAVV 60
MSFHKEDGVNSLCQKALHIVTELCFAGQVEWEKCSGIFPRDRGSQGGSSTDISVSLLAVV
Sbjct: 1 MSFHKEDGVNSLCQKALHIVTELCFAGQVEWEKCSGIFPRDRGSQGGSSTDISVSLLAVV 60
Query: 61 VSFCGLALLVVSLFVFWKLCWPCWKSKPVTSNITTLPQSISSAPTEVFETEEKKEIKENE 120
VSFCGLALLVVSLFVFWKLCWPCWKSKPVTSNITTLPQSISSAPTEVFETEEKKEIKENE
Sbjct: 61 VSFCGLALLVVSLFVFWKLCWPCWKSKPVTSNITTLPQSISSAPTEVFETEEKKEIKENE 120
Query: 121 KPAVKAIEPAIKISHTSPDIPAEVQTALKEHLIKHARVQRQITEPTSSTRHSSFRRHLPR 180
KPAVKAIEPAIKISHTSPDIPAEVQTALKEHLIKHARVQRQITEPTSSTRHSSFRRHLPR
Sbjct: 121 KPAVKAIEPAIKISHTSPDIPAEVQTALKEHLIKHARVQRQITEPTSSTRHSSFRRHLPR 180
Query: 181 QMQVSSVDFSMGTEPVLQRGETTTSIGRIKPELYKQKSVDSEGNQNEDVKICGKLNFTLQ 240
QMQVSSVDFSMGTEPVLQRGETTTSIGRIKPELYKQKSVDSEGNQNEDVKICGKLNFTLQ
Sbjct: 181 QMQVSSVDFSMGTEPVLQRGETTTSIGRIKPELYKQKSVDSEGNQNEDVKICGKLNFTLQ 240
Query: 241 YDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDRKKKFQTRVHRKTLNPLFDETF 300
YDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDRKKKFQTRVHRKTLNPLFDETF
Sbjct: 241 YDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDRKKKFQTRVHRKTLNPLFDETF 300
Query: 301 QFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILDNLFEVSDLSREATVWKDIHCATTE 360
QFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILDNLFEVSDLSREATVWKDIHCATTE
Sbjct: 301 QFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILDNLFEVSDLSREATVWKDIHCATTE 360
Query: 361 SIDLGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTT 420
SIDLGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTT
Sbjct: 361 SIDLGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTT 420
Query: 421 TKKNTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLDAEGLGRDH 480
TKKNTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLDAEGLGRDH
Sbjct: 421 TKKNTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLDAEGLGRDH 480
Query: 481 WNEMLAYHRKPITHWHPLLELPGRATSFDSQGSCPSPKPPSTP 523
WNEMLAYHRKPITHWHPLLELPGRATSFDSQGSCPSPKPPSTP
Sbjct: 481 WNEMLAYHRKPITHWHPLLELPGRATSFDSQGSCPSPKPPSTP 523
>gi|45504376 synaptotagmin VI [Homo sapiens]
Length = 425
Score = 604 bits (1558), Expect = e-173
Identities = 294/418 (70%), Positives = 345/418 (82%), Gaps = 6/418 (1%)
Query: 84 WKSKPVTSNITTLPQSISSAPTEVFETEEKKEIKENEKPAVKAIEPAIKISHTSPDIPAE 143
W++K +S + P + + + F ++K+ + +E A+KISHTSPDIPAE
Sbjct: 3 WRNKEASSPSSANPP-LEALQSPSFRGNMADKLKDPS--TLGFLEAAVKISHTSPDIPAE 59
Query: 144 VQTALKEHLIKHARVQRQITEPTSSTRHSSFRRHLPRQMQVSSVDFSMGTEPVLQRGETT 203
VQ ++KEH+++H R+QRQ TEP SSTRH+SF+RHLPRQM VSSVD+ P E
Sbjct: 60 VQMSVKEHIMRHTRLQRQTTEPASSTRHTSFKRHLPRQMHVSSVDYGNELPPA---AEQP 116
Query: 204 TSIGRIKPELYKQKSVDSEGNQNEDVKICGKLNFTLQYDYENELLVVKIIKALDLPAKDF 263
TSIGRIKPELYKQKSVD E ++E K CGK+NF+L+YDYE E L+V+I+KA DLPAKDF
Sbjct: 117 TSIGRIKPELYKQKSVDGEDAKSEATKSCGKINFSLRYDYETETLIVRILKAFDLPAKDF 176
Query: 264 TGTSDPYVKMYLLPDRKKKFQTRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFSVYDFDR 323
G+SDPYVK+YLLPDRK K QTRVHRKTLNP FDE F FPV Y++L++RKLH SV+DFDR
Sbjct: 177 CGSSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDR 236
Query: 324 FSRHDMIGEVILDNLFEVSDLSREATVWKDIHCATTESIDLGEIMFSLCYLPTAGRMTLT 383
FSRHDMIGEVILDNLFE SDLSRE ++WKDI AT+ES+DLGEIMFSLCYLPTAGR+TLT
Sbjct: 237 FSRHDMIGEVILDNLFEASDLSRETSIWKDIQYATSESVDLGEIMFSLCYLPTAGRLTLT 296
Query: 384 VIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENV 443
VIKCRNLKAMDITG SDPYVKVSL+C+GRRLKK+KTT KKNTLNPVYNEAIIFDIPPEN+
Sbjct: 297 VIKCRNLKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENM 356
Query: 444 DQVSLSIAVMDYDRVGHNEVIGVCRTGLDAEGLGRDHWNEMLAYHRKPITHWHPLLEL 501
DQVSL I+VMDYDRVGHNE+IGVCR G+ AEGLGRDHWNEMLAY RKPI HWH L+E+
Sbjct: 357 DQVSLLISVMDYDRVGHNEIIGVCRVGITAEGLGRDHWNEMLAYPRKPIAHWHSLVEV 414
>gi|28376627 synaptotagmin IX [Homo sapiens]
Length = 491
Score = 595 bits (1535), Expect = e-170
Identities = 294/494 (59%), Positives = 371/494 (75%), Gaps = 13/494 (2%)
Query: 10 NSLCQKALHIVTELCFAGQVEWEKCSGIFP--RDRGSQGGSSTDISVSLLAVVVSFCGLA 67
++LC +AL ++ ELC G +E + C RDR DISVSLL +VV+ CGLA
Sbjct: 6 DALCHQALQLLAELCARGALEHDSCQDFIYHLRDRARPRLRDPDISVSLLTLVVTACGLA 65
Query: 68 LLVVSLFVFWKLCWPCWKSKPVTSNITTLPQS-ISSAPTEVFETEEKKEIKENEKPAVKA 126
L VSLFV WKLCW W+ + + S Q ++ TE E E ++ + P
Sbjct: 66 LFGVSLFVSWKLCWVPWRERGLPSGSKDNNQEPLNYMDTETNEQENSEDFLD---PPTPC 122
Query: 127 IEPAIKISHTSPDIPAEVQTALKEHLIKHARVQRQITEPTSSTRHSSFRRHLPRQMQVSS 186
+ ++KISHTSPDIP QT ++E+ RVQRQ+TEPTSS RH+S RR Q+ +S+
Sbjct: 123 PDSSMKISHTSPDIPLSTQTGIQENCAHGVRVQRQVTEPTSSARHNSIRR----QLNLSN 178
Query: 187 VDFSMGTEPVLQRGETTTSIGRIKPELYKQKSVDSEGNQNEDVKICGKLNFTLQYDYENE 246
DF++ LQ+ E T IGRIKPELYKQ+S+D++ + + K CGKLNF L+YD + E
Sbjct: 179 PDFNIQQ---LQKQEQLTGIGRIKPELYKQRSLDNDDGRRSNSKACGKLNFILKYDCDLE 235
Query: 247 LLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDRKKKFQTRVHRKTLNPLFDETFQFPVAY 306
L+VKI KA++LPAKDF+GTSDPYVK+YLLPDRK K QT+VHRKTLNP+FDE F FPV Y
Sbjct: 236 QLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVPY 295
Query: 307 DQLSNRKLHFSVYDFDRFSRHDMIGEVILDNLFEVSDLSREATVWKDIHCATTESIDLGE 366
+ L RKLHFSVYDFDRFSRHD+IG+V++D+ +++D RE +WKDI T +++DLGE
Sbjct: 296 NDLEARKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWKDIEYVTNDNVDLGE 355
Query: 367 IMFSLCYLPTAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTL 426
+MFSLCYLPTAGR+T+T+IK RNLKAMDITG+SDPYVKVSLMC+GRRLKKRKT+TK+NTL
Sbjct: 356 LMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTL 415
Query: 427 NPVYNEAIIFDIPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLDAEGLGRDHWNEMLA 486
NPVYNEAI+FD+PPEN+DQ+ LSIAVMDYDRVGHNE+IGVC+ G +AE LGRDHW+EML+
Sbjct: 416 NPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGRDHWSEMLS 475
Query: 487 YHRKPITHWHPLLE 500
Y RKPI HWH L+E
Sbjct: 476 YPRKPIAHWHSLVE 489
>gi|238550198 synaptotagmin III [Homo sapiens]
Length = 590
Score = 450 bits (1157), Expect = e-126
Identities = 262/566 (46%), Positives = 343/566 (60%), Gaps = 72/566 (12%)
Query: 7 DGVNSLCQKALHIVTELC--FAGQVEWEKCSGIFPRDRGSQGGSSTDISVSLLAVVVSFC 64
D + LC++AL +V++LC ++C R RG G DISVSLL+V+V+FC
Sbjct: 4 DYEDDLCRRALILVSDLCARVRDADTNDRCQEFNDRIRGYPRGPDADISVSLLSVIVTFC 63
Query: 65 GLALLVVSLFVFWKLCWPCWKSK--------PVTSNITT--------------LPQSISS 102
G+ LL VSLFV WKLCW W+ K P+ ++ L +
Sbjct: 64 GIVLLGVSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLGPGVGLAGLVGGGGHHLAAGLGG 123
Query: 103 AP-----------------TEVFE--------TEEKKEIKENEKPAVKA--IEPAIKISH 135
P E+ E T E + + P A + +K S
Sbjct: 124 HPLLGGPHHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVKPSQ 183
Query: 136 TSPDIPAEVQTALKEHL-------IKHARVQRQITEPTSSTRHSSFRRHLPRQMQVSSVD 188
TSP++P+E L + A+ +Q+T +TR+ + R L +Q S D
Sbjct: 184 TSPELPSEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTSQPD 243
Query: 189 FSMGTEP-----VLQRGETTTS-IGRIKPELYK------QKSVDSEGNQNEDVKI-CGKL 235
S P L GE IG+IKPELY+ ++S G+ CG++
Sbjct: 244 PSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPCGRI 303
Query: 236 NFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDRKKKFQTRVHRKTLNPL 295
+F L+Y Y ++ LVV+I++ALDLPAKD G SDPYVK+YLLPDRKKKFQT+VHRKTLNP+
Sbjct: 304 SFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPV 363
Query: 296 FDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILDNLFEVSDLSREATVWKDIH 355
F+ETFQF V +L+ RKLHFSVYDFDRFSRHD+IG+V+LDNL E+++ + +W+DI
Sbjct: 364 FNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRDIV 423
Query: 356 CATTESIDLGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLK 415
+E DLGE+ FSLCYLPTAGR+T+T+IK NLKAMD+TG SDPYVK SL+ EGRRLK
Sbjct: 424 EGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLK 483
Query: 416 KRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLD-AE 474
KRKT+ KKNTLNP YNEA++FD+ PE+V+ V LSIAV+DYD +GHNEVIGVCR G D A+
Sbjct: 484 KRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAAD 543
Query: 475 GLGRDHWNEMLAYHRKPITHWHPLLE 500
GR+HW EMLA RKP+ HWH L+E
Sbjct: 544 PHGREHWAEMLANPRKPVEHWHQLVE 569
>gi|238550196 synaptotagmin III [Homo sapiens]
Length = 590
Score = 450 bits (1157), Expect = e-126
Identities = 262/566 (46%), Positives = 343/566 (60%), Gaps = 72/566 (12%)
Query: 7 DGVNSLCQKALHIVTELC--FAGQVEWEKCSGIFPRDRGSQGGSSTDISVSLLAVVVSFC 64
D + LC++AL +V++LC ++C R RG G DISVSLL+V+V+FC
Sbjct: 4 DYEDDLCRRALILVSDLCARVRDADTNDRCQEFNDRIRGYPRGPDADISVSLLSVIVTFC 63
Query: 65 GLALLVVSLFVFWKLCWPCWKSK--------PVTSNITT--------------LPQSISS 102
G+ LL VSLFV WKLCW W+ K P+ ++ L +
Sbjct: 64 GIVLLGVSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLGPGVGLAGLVGGGGHHLAAGLGG 123
Query: 103 AP-----------------TEVFE--------TEEKKEIKENEKPAVKA--IEPAIKISH 135
P E+ E T E + + P A + +K S
Sbjct: 124 HPLLGGPHHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVKPSQ 183
Query: 136 TSPDIPAEVQTALKEHL-------IKHARVQRQITEPTSSTRHSSFRRHLPRQMQVSSVD 188
TSP++P+E L + A+ +Q+T +TR+ + R L +Q S D
Sbjct: 184 TSPELPSEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTSQPD 243
Query: 189 FSMGTEP-----VLQRGETTTS-IGRIKPELYK------QKSVDSEGNQNEDVKI-CGKL 235
S P L GE IG+IKPELY+ ++S G+ CG++
Sbjct: 244 PSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPCGRI 303
Query: 236 NFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDRKKKFQTRVHRKTLNPL 295
+F L+Y Y ++ LVV+I++ALDLPAKD G SDPYVK+YLLPDRKKKFQT+VHRKTLNP+
Sbjct: 304 SFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPV 363
Query: 296 FDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILDNLFEVSDLSREATVWKDIH 355
F+ETFQF V +L+ RKLHFSVYDFDRFSRHD+IG+V+LDNL E+++ + +W+DI
Sbjct: 364 FNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRDIV 423
Query: 356 CATTESIDLGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLK 415
+E DLGE+ FSLCYLPTAGR+T+T+IK NLKAMD+TG SDPYVK SL+ EGRRLK
Sbjct: 424 EGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLK 483
Query: 416 KRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLD-AE 474
KRKT+ KKNTLNP YNEA++FD+ PE+V+ V LSIAV+DYD +GHNEVIGVCR G D A+
Sbjct: 484 KRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAAD 543
Query: 475 GLGRDHWNEMLAYHRKPITHWHPLLE 500
GR+HW EMLA RKP+ HWH L+E
Sbjct: 544 PHGREHWAEMLANPRKPVEHWHQLVE 569
>gi|14150054 synaptotagmin III [Homo sapiens]
Length = 590
Score = 450 bits (1157), Expect = e-126
Identities = 262/566 (46%), Positives = 343/566 (60%), Gaps = 72/566 (12%)
Query: 7 DGVNSLCQKALHIVTELC--FAGQVEWEKCSGIFPRDRGSQGGSSTDISVSLLAVVVSFC 64
D + LC++AL +V++LC ++C R RG G DISVSLL+V+V+FC
Sbjct: 4 DYEDDLCRRALILVSDLCARVRDADTNDRCQEFNDRIRGYPRGPDADISVSLLSVIVTFC 63
Query: 65 GLALLVVSLFVFWKLCWPCWKSK--------PVTSNITT--------------LPQSISS 102
G+ LL VSLFV WKLCW W+ K P+ ++ L +
Sbjct: 64 GIVLLGVSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLGPGVGLAGLVGGGGHHLAAGLGG 123
Query: 103 AP-----------------TEVFE--------TEEKKEIKENEKPAVKA--IEPAIKISH 135
P E+ E T E + + P A + +K S
Sbjct: 124 HPLLGGPHHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVKPSQ 183
Query: 136 TSPDIPAEVQTALKEHL-------IKHARVQRQITEPTSSTRHSSFRRHLPRQMQVSSVD 188
TSP++P+E L + A+ +Q+T +TR+ + R L +Q S D
Sbjct: 184 TSPELPSEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTSQPD 243
Query: 189 FSMGTEP-----VLQRGETTTS-IGRIKPELYK------QKSVDSEGNQNEDVKI-CGKL 235
S P L GE IG+IKPELY+ ++S G+ CG++
Sbjct: 244 PSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPCGRI 303
Query: 236 NFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDRKKKFQTRVHRKTLNPL 295
+F L+Y Y ++ LVV+I++ALDLPAKD G SDPYVK+YLLPDRKKKFQT+VHRKTLNP+
Sbjct: 304 SFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPV 363
Query: 296 FDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILDNLFEVSDLSREATVWKDIH 355
F+ETFQF V +L+ RKLHFSVYDFDRFSRHD+IG+V+LDNL E+++ + +W+DI
Sbjct: 364 FNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRDIV 423
Query: 356 CATTESIDLGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLK 415
+E DLGE+ FSLCYLPTAGR+T+T+IK NLKAMD+TG SDPYVK SL+ EGRRLK
Sbjct: 424 EGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLK 483
Query: 416 KRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLD-AE 474
KRKT+ KKNTLNP YNEA++FD+ PE+V+ V LSIAV+DYD +GHNEVIGVCR G D A+
Sbjct: 484 KRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAAD 543
Query: 475 GLGRDHWNEMLAYHRKPITHWHPLLE 500
GR+HW EMLA RKP+ HWH L+E
Sbjct: 544 PHGREHWAEMLANPRKPVEHWHQLVE 569
>gi|209447073 synaptotagmin I [Homo sapiens]
Length = 422
Score = 288 bits (738), Expect = 6e-78
Identities = 139/282 (49%), Positives = 195/282 (69%), Gaps = 6/282 (2%)
Query: 221 SEGNQNEDVKI---CGKLNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLP 277
++G + E+ K GKL ++L YD++N L+V II+A +LPA D GTSDPYVK++LLP
Sbjct: 129 TDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLP 188
Query: 278 DRKKKFQTRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILDN 337
D+KKKF+T+VHRKTLNP+F+E F F V Y +L + L +VYDFDRFS+HD+IGE +
Sbjct: 189 DKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVP- 247
Query: 338 LFEVSDLSREATVWKDIHCATTESID-LGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDIT 396
D W+D+ A E + LG+I FSL Y+PTAG++T+ +++ +NLK MD+
Sbjct: 248 -MNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVG 306
Query: 397 GSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYD 456
G SDPYVK+ LM G+RLKK+KTT KKNTLNP YNE+ F++P E + +V + + V+DYD
Sbjct: 307 GLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYD 366
Query: 457 RVGHNEVIGVCRTGLDAEGLGRDHWNEMLAYHRKPITHWHPL 498
++G N+ IG G ++ G HW++MLA R+PI WH L
Sbjct: 367 KIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTL 408
Score = 77.0 bits (188), Expect = 4e-14
Identities = 40/118 (33%), Positives = 72/118 (61%), Gaps = 2/118 (1%)
Query: 220 DSEGNQNEDVKICGKLNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLPD- 278
D + + E+ + G + F+L+Y L V I++A +L D G SDPYVK++L+ +
Sbjct: 262 DLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNG 321
Query: 279 -RKKKFQTRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVIL 335
R KK +T + + TLNP ++E+F F V ++Q+ ++ +V D+D+ ++D IG+V +
Sbjct: 322 KRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFV 379
>gi|5032139 synaptotagmin I [Homo sapiens]
Length = 422
Score = 288 bits (738), Expect = 6e-78
Identities = 139/282 (49%), Positives = 195/282 (69%), Gaps = 6/282 (2%)
Query: 221 SEGNQNEDVKI---CGKLNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLP 277
++G + E+ K GKL ++L YD++N L+V II+A +LPA D GTSDPYVK++LLP
Sbjct: 129 TDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLP 188
Query: 278 DRKKKFQTRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILDN 337
D+KKKF+T+VHRKTLNP+F+E F F V Y +L + L +VYDFDRFS+HD+IGE +
Sbjct: 189 DKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVP- 247
Query: 338 LFEVSDLSREATVWKDIHCATTESID-LGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDIT 396
D W+D+ A E + LG+I FSL Y+PTAG++T+ +++ +NLK MD+
Sbjct: 248 -MNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVG 306
Query: 397 GSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYD 456
G SDPYVK+ LM G+RLKK+KTT KKNTLNP YNE+ F++P E + +V + + V+DYD
Sbjct: 307 GLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYD 366
Query: 457 RVGHNEVIGVCRTGLDAEGLGRDHWNEMLAYHRKPITHWHPL 498
++G N+ IG G ++ G HW++MLA R+PI WH L
Sbjct: 367 KIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTL 408
Score = 77.0 bits (188), Expect = 4e-14
Identities = 40/118 (33%), Positives = 72/118 (61%), Gaps = 2/118 (1%)
Query: 220 DSEGNQNEDVKICGKLNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLPD- 278
D + + E+ + G + F+L+Y L V I++A +L D G SDPYVK++L+ +
Sbjct: 262 DLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNG 321
Query: 279 -RKKKFQTRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVIL 335
R KK +T + + TLNP ++E+F F V ++Q+ ++ +V D+D+ ++D IG+V +
Sbjct: 322 KRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFV 379
>gi|209447070 synaptotagmin I [Homo sapiens]
Length = 422
Score = 288 bits (738), Expect = 6e-78
Identities = 139/282 (49%), Positives = 195/282 (69%), Gaps = 6/282 (2%)
Query: 221 SEGNQNEDVKI---CGKLNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLP 277
++G + E+ K GKL ++L YD++N L+V II+A +LPA D GTSDPYVK++LLP
Sbjct: 129 TDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLP 188
Query: 278 DRKKKFQTRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILDN 337
D+KKKF+T+VHRKTLNP+F+E F F V Y +L + L +VYDFDRFS+HD+IGE +
Sbjct: 189 DKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVP- 247
Query: 338 LFEVSDLSREATVWKDIHCATTESID-LGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDIT 396
D W+D+ A E + LG+I FSL Y+PTAG++T+ +++ +NLK MD+
Sbjct: 248 -MNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVG 306
Query: 397 GSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYD 456
G SDPYVK+ LM G+RLKK+KTT KKNTLNP YNE+ F++P E + +V + + V+DYD
Sbjct: 307 GLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYD 366
Query: 457 RVGHNEVIGVCRTGLDAEGLGRDHWNEMLAYHRKPITHWHPL 498
++G N+ IG G ++ G HW++MLA R+PI WH L
Sbjct: 367 KIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTL 408
Score = 77.0 bits (188), Expect = 4e-14
Identities = 40/118 (33%), Positives = 72/118 (61%), Gaps = 2/118 (1%)
Query: 220 DSEGNQNEDVKICGKLNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLPD- 278
D + + E+ + G + F+L+Y L V I++A +L D G SDPYVK++L+ +
Sbjct: 262 DLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNG 321
Query: 279 -RKKKFQTRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVIL 335
R KK +T + + TLNP ++E+F F V ++Q+ ++ +V D+D+ ++D IG+V +
Sbjct: 322 KRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFV 379
>gi|211059429 synaptotagmin II [Homo sapiens]
Length = 419
Score = 285 bits (729), Expect = 7e-77
Identities = 136/280 (48%), Positives = 193/280 (68%), Gaps = 3/280 (1%)
Query: 220 DSEGNQNEDVKICGKLNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDR 279
+ EG + ++ + GKL F+L YD++ L V +++A +LPA D GTSDPYVK++LLPD+
Sbjct: 128 EGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDK 187
Query: 280 KKKFQTRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILDNLF 339
KKK++T+VHRKTLNP F+ETF F V Y +L + L ++YDFDRFS+HD+IGEV +
Sbjct: 188 KKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVP--M 245
Query: 340 EVSDLSREATVWKDIHCATTESID-LGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGS 398
DL + W+D+ E + LG+I SL Y+PTAG++T+ +++ +NLK MD+ G
Sbjct: 246 NTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGL 305
Query: 399 SDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYDRV 458
SDPYVK+ LM G+RLKK+KTT KK TLNP +NE+ F+IP E + +V + + V+DYD++
Sbjct: 306 SDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKL 365
Query: 459 GHNEVIGVCRTGLDAEGLGRDHWNEMLAYHRKPITHWHPL 498
G NE IG G +A G HW++MLA R+PI WH L
Sbjct: 366 GKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSL 405
>gi|31543670 synaptotagmin II [Homo sapiens]
Length = 419
Score = 285 bits (729), Expect = 7e-77
Identities = 136/280 (48%), Positives = 193/280 (68%), Gaps = 3/280 (1%)
Query: 220 DSEGNQNEDVKICGKLNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDR 279
+ EG + ++ + GKL F+L YD++ L V +++A +LPA D GTSDPYVK++LLPD+
Sbjct: 128 EGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDK 187
Query: 280 KKKFQTRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILDNLF 339
KKK++T+VHRKTLNP F+ETF F V Y +L + L ++YDFDRFS+HD+IGEV +
Sbjct: 188 KKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVP--M 245
Query: 340 EVSDLSREATVWKDIHCATTESID-LGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGS 398
DL + W+D+ E + LG+I SL Y+PTAG++T+ +++ +NLK MD+ G
Sbjct: 246 NTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGL 305
Query: 399 SDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYDRV 458
SDPYVK+ LM G+RLKK+KTT KK TLNP +NE+ F+IP E + +V + + V+DYD++
Sbjct: 306 SDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKL 365
Query: 459 GHNEVIGVCRTGLDAEGLGRDHWNEMLAYHRKPITHWHPL 498
G NE IG G +A G HW++MLA R+PI WH L
Sbjct: 366 GKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSL 405
>gi|92859638 synaptotagmin V [Homo sapiens]
Length = 386
Score = 279 bits (713), Expect = 5e-75
Identities = 140/302 (46%), Positives = 203/302 (67%), Gaps = 4/302 (1%)
Query: 199 RGETTTSIGRIKPELYKQKSVDS-EGNQNEDVKICGKLNFTLQYDYENELLVVKIIKALD 257
+G + I +++PE+ + + S G Q D G+L ++L YD+++ L+V I++A+
Sbjct: 75 KGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMG 134
Query: 258 LPAKDFTGTSDPYVKMYLLPDRKKKFQTRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFS 317
L A D G+SDPYV++YLLPD++++++T+VHR+TLNP F ETF F V Y +L R L +
Sbjct: 135 LAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFKVPYVELGGRVLVMA 194
Query: 318 VYDFDRFSRHDMIGEVILDNLFEVSDLSREATVWKDIHCATTESID-LGEIMFSLCYLPT 376
VYDFDRFSR+D IGEV + DL R W+++ A E + LG+I FSL Y+PT
Sbjct: 195 VYDFDRFSRNDAIGEVRVP--MSSVDLGRPVQAWRELQAAPREEQEKLGDICFSLRYVPT 252
Query: 377 AGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIF 436
AG++T+ V++ +NLK MD+ G SDPYVKV L+ G++++K+KTT KKNTLNP YNEA F
Sbjct: 253 AGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSF 312
Query: 437 DIPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLDAEGLGRDHWNEMLAYHRKPITHWH 496
++P + V +V + + V+DYD++G NE IG G A G G HW +MLA R+PI WH
Sbjct: 313 EVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADMLANPRRPIAQWH 372
Query: 497 PL 498
L
Sbjct: 373 SL 374
>gi|38570146 synaptotagmin VII [Homo sapiens]
Length = 403
Score = 251 bits (641), Expect = 1e-66
Identities = 130/308 (42%), Positives = 196/308 (63%), Gaps = 9/308 (2%)
Query: 198 QRGETTTSIGRIKPELYKQKSVDSEGNQNEDV------KICGKLNFTLQYDYENELLVVK 251
+R E +S+ + L + + S G++ ++ + G++ F++ Y+++ L VK
Sbjct: 96 RRTEPRSSVSDLVNSLTSEMLMLSPGSEEDEAHEGCSRENLGRIQFSVGYNFQESTLTVK 155
Query: 252 IIKALDLPAKDFTGTSDPYVKMYLLPDRKKKFQTRVHRKTLNPLFDETFQFP-VAYDQLS 310
I+KA +LPAKDF+GTSDP+VK+YLLPD+K K +T+V RK LNP ++ETF F Y+++
Sbjct: 156 IMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVV 215
Query: 311 NRKLHFSVYDFDRFSRHDMIGEVILDNLFEVSDLSREATVWKDIHCATTESIDLGEIMFS 370
R L+ V D+DRFSR+D IGEV + DL++ T WKD+ + S GE++ S
Sbjct: 216 QRILYLQVLDYDRFSRNDPIGEVSIP--LNKVDLTQMQTFWKDLKPCSDGSGSRGELLLS 273
Query: 371 LCYLPTAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVY 430
LCY P+A + + +IK RNLKAMDI G+SDPYVKV LM + +R++K+KT T K LNP++
Sbjct: 274 LCYNPSANSIIVNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTMKRNLNPIF 333
Query: 431 NEAIIFDIPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLDAEGLGRDHWNEMLAYHRK 490
NE+ FDIP E + + ++ I VMD D++ N+VIG + HW +M+A R+
Sbjct: 334 NESFAFDIPTEKLRETTIIITVMDKDKLSRNDVIGKIYLSWKSGPGEVKHWKDMIARPRQ 393
Query: 491 PITHWHPL 498
P+ WH L
Sbjct: 394 PVAQWHQL 401
>gi|24308219 synaptotagmin IV [Homo sapiens]
Length = 425
Score = 224 bits (572), Expect = 1e-58
Identities = 132/323 (40%), Positives = 185/323 (57%), Gaps = 19/323 (5%)
Query: 185 SSVDFSMGTEPVLQRGETTTSIGRIKPELYKQK-SVDSEGNQNEDVKICGKLNFTLQYDY 243
S D T + GE + + PE K S+ SE Q + G L F+L+Y++
Sbjct: 114 SPSDLENATPKLFLEGEKES----VSPESLKSSTSLTSEEKQEK----LGTLFFSLEYNF 165
Query: 244 ENELLVVKIIKALDLPAKDFTG-TSDPYVKMYLLPDRKKKFQTRVHRKTLNPLFDETFQF 302
E + VV I +A LPA D TSDPY+KM +LP++K K +TRV RKTL+P FDETF F
Sbjct: 166 ERKAFVVNIKEARGLPAMDEQSMTSDPYIKMTILPEKKHKVKTRVLRKTLDPAFDETFTF 225
Query: 303 -PVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILD----NLFEVSDLSREATVWKDIHCA 357
+ Y Q+ LHF++ FDRFSR D+IGEV++ L E L + +++
Sbjct: 226 YGIPYTQIQELALHFTILSFDRFSRDDIIGEVLIPLSGIELSEGKMLMNREIIKRNVR-- 283
Query: 358 TTESIDLGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKR 417
+S GE++ SLCY T +T+ V+K R+L D++G SDPYVKV+L +R+ K+
Sbjct: 284 --KSSGRGELLISLCYQSTTNTLTVVVLKARHLPKSDVSGLSDPYVKVNLYHAKKRISKK 341
Query: 418 KTTTKKNTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLDAEGLG 477
KT KK T N V+NE +FDIP E ++ +S+ V+D +R NEVIG G AEG G
Sbjct: 342 KTHVKKCTPNAVFNELFVFDIPCEGLEDISVEFLVLDSERGSRNEVIGQLVLGAAAEGTG 401
Query: 478 RDHWNEMLAYHRKPITHWHPLLE 500
+HW E+ Y R+ I WH L +
Sbjct: 402 GEHWKEICDYPRRQIAKWHVLCD 424
>gi|216548478 synaptotagmin XI [Homo sapiens]
Length = 431
Score = 216 bits (550), Expect = 4e-56
Identities = 125/290 (43%), Positives = 176/290 (60%), Gaps = 7/290 (2%)
Query: 216 QKSVDSEGNQNEDVKICGKLNFTLQYDYENELLVVKIIKALDLPAKDF-TGTSDPYVKMY 274
+ S + EDV + G L F++ Y++ + LVV I +A LP D T SDPY+KM
Sbjct: 143 ESKTTSPSSPEEDVML-GSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMT 201
Query: 275 LLPDRKKKFQTRVHRKTLNPLFDETFQF-PVAYDQLSNRKLHFSVYDFDRFSRHDMIGEV 333
+LPD++ + +TRV RKTL+P+FDETF F + Y QL + LHF V FDRFSR D+IGEV
Sbjct: 202 ILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEV 261
Query: 334 ILDNLFEVSDLSREATVWKDIHCATTES-IDLGEIMFSLCYLPTAGRMTLTVIKCRNLKA 392
++ L V + + + +DI + I GE+ SL Y P A RMT+ V+K R+L
Sbjct: 262 MVP-LAGVDPSTGKVQLTRDIIKRNIQKCISRGELQVSLSYQPVAQRMTVVVLKARHLPK 320
Query: 393 MDITG-SSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLSIA 451
MDITG S +PYVKV++ +R+ K+KT KK TLNP++NE+ I+DIP + + +S+
Sbjct: 321 MDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTDLLPDISIEFL 380
Query: 452 VMDYDRVGHNEVIGVCRTGL-DAEGLGRDHWNEMLAYHRKPITHWHPLLE 500
V+D+DR NEV+G G G +HW E+ RKP+ WH L E
Sbjct: 381 VIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPRKPVAKWHSLSE 430
>gi|40068038 B/K protein [Homo sapiens]
Length = 474
Score = 186 bits (471), Expect = 6e-47
Identities = 108/304 (35%), Positives = 170/304 (55%), Gaps = 15/304 (4%)
Query: 208 RIKPELYKQKSVDSEGNQNEDVKICGK-----LNFTLQYDYENELLVVKIIKALDLP--- 259
+ +P LY S + + D +I K L+F+ QYD + L V++I+A DLP
Sbjct: 156 KFEPHLYSLDSNSDDVDSLTDEEILSKYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPI 215
Query: 260 ----AKDFTGTSDPYVKMYLLPDRKKKFQTRVHRKTLNPLFDETFQFPVAYDQLSNRKLH 315
++ S+PYVK+ LLPD+K QT V RKT P+F+E + F + + + R L
Sbjct: 216 SHDGSRQDMAHSNPYVKICLLPDQKNSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLL 275
Query: 316 FSVYDFDRFSRHDMIGEVILDNLFEVSDLSREATVWKDIHCATTESIDLGEIMFSLCYLP 375
+V DFD+FSRH +IG+V + L EV DL + WK + ++ ++LGE++ SL YLP
Sbjct: 276 LTVVDFDKFSRHCVIGKVSVP-LCEV-DLVKGGHWWKALIPSSQNEVELGELLLSLNYLP 333
Query: 376 TAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAII 435
+AGR+ + VI+ + L D++ SDP+VK+ L+ + +K +KT+ + T++P YNE+
Sbjct: 334 SAGRLNVDVIRAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFS 393
Query: 436 FDIPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLDAEGLGR-DHWNEMLAYHRKPITH 494
F +P E ++ SL V ++ N+ IG G + G +HW ML HR +
Sbjct: 394 FKVPQEELENASLVFTVFGHNMKSSNDFIGRIVIGQYSSGPSETNHWRRMLNTHRTAVEQ 453
Query: 495 WHPL 498
WH L
Sbjct: 454 WHSL 457
>gi|94536846 synaptotagmin VIII [Homo sapiens]
Length = 401
Score = 171 bits (432), Expect = 2e-42
Identities = 113/325 (34%), Positives = 164/325 (50%), Gaps = 24/325 (7%)
Query: 175 RRHLPRQMQVSSVDFSMGTEPVLQRGETTTSIGRIKPELYKQKSVDSEGNQNEDVKICGK 234
RRH + SV RG TTT + Q VD + D + G+
Sbjct: 75 RRHRKKPRDKESVGLGSA------RGTTTTHL--------VQPDVDGLESSPGDAQQWGR 120
Query: 235 LNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDRKKKFQTRVHRKTLNP 294
L +L++D+ ++ + V + +A DL GT DPY ++ + + +T+VHR TL P
Sbjct: 121 LQLSLEFDFGSQEIRVGLRQAADLRPG---GTVDPYARVSVSTQAGHRHETKVHRGTLCP 177
Query: 295 LFDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILDNLFEVSDLSREATVWKDI 354
+FDET F + +L L +++F RFS H+ +GE+ L DL W +
Sbjct: 178 VFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLP--LGTVDLQHVLEHWYLL 235
Query: 355 HC-ATTESIDLGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRR 413
A T+ +GE+ FSL Y+P++GR+T+ V++ R L+ G ++PYVKV LM R+
Sbjct: 236 GPPAATQPEQVGELCFSLRYVPSSGRLTVVVLEARGLRP----GLAEPYVKVQLMLNQRK 291
Query: 414 LKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLDA 473
KKRKT TKK T P +NEA F +P V V L +AV D E +G G A
Sbjct: 292 WKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARA 351
Query: 474 EGLGRDHWNEMLAYHRKPITHWHPL 498
G HW +MLA+ R+PI HPL
Sbjct: 352 SGQPLQHWADMLAHARRPIAQRHPL 376
>gi|31881675 synaptotagmin XV isoform a [Homo sapiens]
Length = 421
Score = 166 bits (419), Expect = 6e-41
Identities = 103/298 (34%), Positives = 161/298 (54%), Gaps = 11/298 (3%)
Query: 206 IGRIKPELYKQKSVDSEGNQNEDVKICGKLNFTLQYDYENELLVVKIIKALDLPAKDFTG 265
+G I PELYK SE + + G+L F+++Y+ E E L+V +IKA L A +
Sbjct: 124 VGAINPELYKFPEDKSETDFPDGC--LGRLWFSVEYEQEAERLLVGLIKAQHLQAP--SE 179
Query: 266 TSDPYVKMYLLPDRKKKFQTRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFSVYDFDRFS 325
T P VK+YLLPD ++ Q++ RKT NP FDE F F V+ ++ R L FSVY DR
Sbjct: 180 TCSPLVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQR 239
Query: 326 RHDMIGEVI--LDNLFEVSDLSREATVWKDIHCATTE-SIDLGEIMFSLCYLPTAGRMTL 382
+H ++G+V+ L N V D R +W+D+ + E + G++ F L Y R+T+
Sbjct: 240 KHQLLGQVLFPLKNETLVGDCRR--VIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTV 297
Query: 383 TVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPEN 442
V++ + L+ + G +VKVSLM + +K +KT+ ++NPVYNE F
Sbjct: 298 VVLRAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATE 357
Query: 443 VDQVSLSIAVMDYDRVGHNEVIGVCRTG--LDAEGLGRDHWNEMLAYHRKPITHWHPL 498
+D SLS+ V+ ++ +G G + G +HW+EML+ ++ + WH L
Sbjct: 358 LDTASLSLTVVQNMEGDKSQQLGRVVVGPYMYTRGRELEHWDEMLSKPKELVKRWHAL 415
>gi|6005997 double C2-like domains, beta [Homo sapiens]
Length = 412
Score = 164 bits (416), Expect = 1e-40
Identities = 110/297 (37%), Positives = 152/297 (51%), Gaps = 9/297 (3%)
Query: 220 DSEGNQNEDVKICGKLNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDR 279
D++G +++D G L+F+L YD EN L I KA L D G +DPYVK++LLP
Sbjct: 115 DADGYESDDCTALGTLDFSLLYDQENNALHCTITKAKGLKPMDHNGLADPYVKLHLLPGA 174
Query: 280 KK--KFQTRVHRKTLNPLFDETFQFPVAYDQLSNRK-LHFSVYDFDRFSRHDMIGE--VI 334
K K +T+ R TLNP ++ET + D+ RK L SV D D+F ++ IGE V
Sbjct: 175 SKANKLRTKTLRNTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGETRVP 234
Query: 335 LDNLFEVSDLSREATVWKDIHCATTESIDL---GEIMFSLCYLPTAGRMTLTVIKCRNLK 391
L L + + K + TE L G I+ SL Y + + +++C +L
Sbjct: 235 LKKLKPNHTKTFNICLEKQLPVDKTEDKSLEERGRILISLKYSSQKQGLLVGIVRCAHLA 294
Query: 392 AMDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLSIA 451
AMD G SDPYVK L + + K KT KK TLNP +NE ++I ++ + SL +
Sbjct: 295 AMDANGYSDPYVKTYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYEIKHGDLAKKSLEVT 354
Query: 452 VMDYDRVGHNEVIGVCRTGLDAEGLGRDHWNEMLAYHRKPITHWHPLL-ELPGRATS 507
V DYD N+ IG G+ A+G HW + L K I WH L ELPG S
Sbjct: 355 VWDYDIGKSNDFIGGVVLGIHAKGERLKHWFDCLKNKDKRIERWHTLTSELPGAVLS 411
Score = 89.4 bits (220), Expect = 7e-18
Identities = 49/144 (34%), Positives = 83/144 (57%), Gaps = 8/144 (5%)
Query: 200 GETTTSIGRIKPELYK------QKSVDSEGNQNEDVKICGKLNFTLQYDYENELLVVKII 253
GET + ++KP K +K + + +++ ++ G++ +L+Y + + L+V I+
Sbjct: 229 GETRVPLKKLKPNHTKTFNICLEKQLPVDKTEDKSLEERGRILISLKYSSQKQGLLVGIV 288
Query: 254 KALDLPAKDFTGTSDPYVKMYLLP--DRKKKFQTRVHRKTLNPLFDETFQFPVAYDQLSN 311
+ L A D G SDPYVK YL P D+K K +T V +KTLNP F+E F + + + L+
Sbjct: 289 RCAHLAAMDANGYSDPYVKTYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYEIKHGDLAK 348
Query: 312 RKLHFSVYDFDRFSRHDMIGEVIL 335
+ L +V+D+D +D IG V+L
Sbjct: 349 KSLEVTVWDYDIGKSNDFIGGVVL 372
>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
Length = 694
Score = 159 bits (403), Expect = 5e-39
Identities = 106/315 (33%), Positives = 153/315 (48%), Gaps = 26/315 (8%)
Query: 210 KPELYKQKSVDSEGNQNEDVKICGKLNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDP 269
+P +++ ++ +++ G L F+L YD +N L IIKA L D G +DP
Sbjct: 371 QPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADP 430
Query: 270 YVKMYLLPDRKK--KFQTRVHRKTLNPLFDETFQFPVAYDQLSNRK-LHFSVYDFDRFSR 326
YVK++LLP K K +T+ R T NP+++ET + D+ RK L SV D D+F
Sbjct: 431 YVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGH 490
Query: 327 HDMIGEVILDN--------------LFEVSDLSREATVWKDIHCATTESIDL-------- 364
++ IGE L V + R T A E +
Sbjct: 491 NEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEE 550
Query: 365 -GEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKK 423
G+I+ SL Y G + + +I+C +L AMD G SDP+VK+ L + + K KT KK
Sbjct: 551 RGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKK 610
Query: 424 NTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLDAEGLGRDHWNE 483
TLNP +NE +DI ++ + SL I+V DYD N+ IG C+ G+ A+G HW E
Sbjct: 611 KTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYE 670
Query: 484 MLAYHRKPITHWHPL 498
L K I WH L
Sbjct: 671 CLKNKDKKIERWHQL 685
Score = 84.7 bits (208), Expect = 2e-16
Identities = 49/139 (35%), Positives = 82/139 (58%), Gaps = 9/139 (6%)
Query: 195 PVLQRGETTTSIGRIKPELYKQKSVDSEGNQNEDVKICGKLNFTLQYDYENELLVVKIIK 254
P+ + G T ++ G LY+++ V+ G D++ GK+ +L Y + L+V II+
Sbjct: 521 PMKRAGTTGSARGMA---LYEEEQVERVG----DIEERGKILVSLMYSTQQGGLIVGIIR 573
Query: 255 ALDLPAKDFTGTSDPYVKMYLLPD--RKKKFQTRVHRKTLNPLFDETFQFPVAYDQLSNR 312
+ L A D G SDP+VK++L PD +K K +T++ +KTLNP F+E F + + + L+ +
Sbjct: 574 CVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKK 633
Query: 313 KLHFSVYDFDRFSRHDMIG 331
L SV+D+D +D IG
Sbjct: 634 SLDISVWDYDIGKSNDYIG 652
>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
Length = 690
Score = 159 bits (403), Expect = 5e-39
Identities = 106/315 (33%), Positives = 153/315 (48%), Gaps = 26/315 (8%)
Query: 210 KPELYKQKSVDSEGNQNEDVKICGKLNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDP 269
+P +++ ++ +++ G L F+L YD +N L IIKA L D G +DP
Sbjct: 367 QPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADP 426
Query: 270 YVKMYLLPDRKK--KFQTRVHRKTLNPLFDETFQFPVAYDQLSNRK-LHFSVYDFDRFSR 326
YVK++LLP K K +T+ R T NP+++ET + D+ RK L SV D D+F
Sbjct: 427 YVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGH 486
Query: 327 HDMIGEVILDN--------------LFEVSDLSREATVWKDIHCATTESIDL-------- 364
++ IGE L V + R T A E +
Sbjct: 487 NEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEE 546
Query: 365 -GEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKK 423
G+I+ SL Y G + + +I+C +L AMD G SDP+VK+ L + + K KT KK
Sbjct: 547 RGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKK 606
Query: 424 NTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLDAEGLGRDHWNE 483
TLNP +NE +DI ++ + SL I+V DYD N+ IG C+ G+ A+G HW E
Sbjct: 607 KTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYE 666
Query: 484 MLAYHRKPITHWHPL 498
L K I WH L
Sbjct: 667 CLKNKDKKIERWHQL 681
Score = 84.7 bits (208), Expect = 2e-16
Identities = 49/139 (35%), Positives = 82/139 (58%), Gaps = 9/139 (6%)
Query: 195 PVLQRGETTTSIGRIKPELYKQKSVDSEGNQNEDVKICGKLNFTLQYDYENELLVVKIIK 254
P+ + G T ++ G LY+++ V+ G D++ GK+ +L Y + L+V II+
Sbjct: 517 PMKRAGTTGSARGMA---LYEEEQVERVG----DIEERGKILVSLMYSTQQGGLIVGIIR 569
Query: 255 ALDLPAKDFTGTSDPYVKMYLLPD--RKKKFQTRVHRKTLNPLFDETFQFPVAYDQLSNR 312
+ L A D G SDP+VK++L PD +K K +T++ +KTLNP F+E F + + + L+ +
Sbjct: 570 CVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKK 629
Query: 313 KLHFSVYDFDRFSRHDMIG 331
L SV+D+D +D IG
Sbjct: 630 SLDISVWDYDIGKSNDYIG 648
>gi|29366828 synaptotagmin XII [Homo sapiens]
Length = 421
Score = 159 bits (401), Expect = 8e-39
Identities = 91/280 (32%), Positives = 150/280 (53%), Gaps = 3/280 (1%)
Query: 218 SVDSEGNQNEDVKICGKLNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLP 277
S+ S N G++ +++YD + L V +++ DL ++ ++++ LLP
Sbjct: 139 SISSVSNTFGQDFTLGQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLP 198
Query: 278 DRKKKFQTRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILDN 337
D + +R+ R + FDE F P+ L + L FSV+ D R+ G V L
Sbjct: 199 DEQIVGISRIQRNAYSIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELK- 257
Query: 338 LFEVSDLSREA-TVWKDIHCATTESIDLGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDIT 396
V DL + + W + + +GEI+ SL YLPTA R+T+ V+K +NL +
Sbjct: 258 -LSVLDLPLQPFSGWLYLQDQNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDK 316
Query: 397 GSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYD 456
++DP+VKV L+ +GR++ K+KT K++ NPV+NEA+IF +P + +SL + V +
Sbjct: 317 TTADPFVKVYLLQDGRKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESS 376
Query: 457 RVGHNEVIGVCRTGLDAEGLGRDHWNEMLAYHRKPITHWH 496
G + +G G A G+G HWN+MLA R+P++ WH
Sbjct: 377 SDGRGDNVGHVIIGPSASGMGTTHWNQMLATLRRPVSMWH 416
>gi|31881667 synaptotagmin XV isoform b [Homo sapiens]
Length = 390
Score = 150 bits (378), Expect = 4e-36
Identities = 92/251 (36%), Positives = 140/251 (55%), Gaps = 9/251 (3%)
Query: 206 IGRIKPELYKQKSVDSEGNQNEDVKICGKLNFTLQYDYENELLVVKIIKALDLPAKDFTG 265
+G I PELYK SE + + G+L F+++Y+ E E L+V +IKA L A +
Sbjct: 124 VGAINPELYKFPEDKSETDFPDGC--LGRLWFSVEYEQEAERLLVGLIKAQHLQAP--SE 179
Query: 266 TSDPYVKMYLLPDRKKKFQTRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFSVYDFDRFS 325
T P VK+YLLPD ++ Q++ RKT NP FDE F F V+ ++ R L FSVY DR
Sbjct: 180 TCSPLVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQR 239
Query: 326 RHDMIGEVI--LDNLFEVSDLSREATVWKDIHCATTE-SIDLGEIMFSLCYLPTAGRMTL 382
+H ++G+V+ L N V D R +W+D+ + E + G++ F L Y R+T+
Sbjct: 240 KHQLLGQVLFPLKNETLVGDCRR--VIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTV 297
Query: 383 TVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPEN 442
V++ + L+ + G +VKVSLM + +K +KT+ ++NPVYNE F
Sbjct: 298 VVLRAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATE 357
Query: 443 VDQVSLSIAVM 453
+D SLS+ V+
Sbjct: 358 LDTASLSLTVV 368
Score = 52.8 bits (125), Expect = 8e-07
Identities = 41/132 (31%), Positives = 67/132 (50%), Gaps = 8/132 (6%)
Query: 364 LGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKK 423
LG + FS+ Y A R+ + +IK ++L+A T S P VK+ L+ + RR + KT K+
Sbjct: 148 LGRLWFSVEYEQEAERLLVGLIKAQHLQAPSETCS--PLVKLYLLPDERRFLQSKT--KR 203
Query: 424 NTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLDAEGLGRD---- 479
T NP ++E IF + + + Q L +V DR ++++G L E L D
Sbjct: 204 KTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDCRRV 263
Query: 480 HWNEMLAYHRKP 491
W ++ A +P
Sbjct: 264 IWRDLEAESLEP 275
>gi|47078261 double C2-like domains, alpha [Homo sapiens]
Length = 400
Score = 149 bits (377), Expect = 5e-36
Identities = 98/326 (30%), Positives = 152/326 (46%), Gaps = 31/326 (9%)
Query: 216 QKSVDSEGNQNEDVKICGKLNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYL 275
+ + + ++D G L F L YD + L I++A L DF G +DPYVK++L
Sbjct: 74 EDGAEVDSYDSDDATALGTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHL 133
Query: 276 LPDRKK--KFQTRVHRKTLNPLFDETFQFP-VAYDQLSNRKLHFSVYDFDRFSRHDMIGE 332
LP K K +T+ R TLNP+++E + + D ++++ L +V D D+ S ++ IGE
Sbjct: 134 LPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGE 193
Query: 333 V-----------------ILDNLFEVSDLSREATVWKDIHCATTESI----------DLG 365
+ L+ ++ S + + I C E + G
Sbjct: 194 IRVPLRRLKPSQKKHFNICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLEERG 253
Query: 366 EIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNT 425
I+ SL Y + + +++C +L AMD+ G SDPYVK L + + K KT KK T
Sbjct: 254 RILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKT 313
Query: 426 LNPVYNEAIIFDIPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLDAEGLGRDHWNEML 485
LNP +NE ++I + +L + V DYD N+ IG G A G R HW++ L
Sbjct: 314 LNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEARKHWSDCL 373
Query: 486 AYHRKPITHWHPLL-ELPGRATSFDS 510
+ WH L ELP A + S
Sbjct: 374 QQPDAALERWHTLTSELPPAAGALSS 399
>gi|24308233 synaptotagmin XIII [Homo sapiens]
Length = 426
Score = 134 bits (338), Expect = 2e-31
Identities = 85/270 (31%), Positives = 144/270 (53%), Gaps = 11/270 (4%)
Query: 234 KLNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDRKK-KFQTRVHRKTL 292
KL++ L YD + L V ++A+ + G D YV+ + + QT + ++ L
Sbjct: 161 KLHYCLDYDCQKAELFVTRLEAV---TSNHDGGCDCYVQGSVANRTGSVEAQTALKKRQL 217
Query: 293 NPLFDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILDNLFEVSDLSREATVWK 352
+ ++E P+A ++L L ++ DRFSRH + GE+ L + + + A W
Sbjct: 218 HTTWEEGLVLPLAEEELPTATLTLTLRTCDRFSRHSVAGELRLG--LDGTSVPLGAAQWG 275
Query: 353 DIHCATTE-SIDLGEIMFSLCYLPTAGRMTLTVIKCRNL---KAMDITGSSDPYVKVSLM 408
++ + E S GE++ S+ YLP A R+ + +IK +NL ++ ++ G D VKV+L
Sbjct: 276 ELKTSAKEPSAGAGEVLLSISYLPAANRLLVVLIKAKNLHSNQSKELLGK-DVSVKVTLK 334
Query: 409 CEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYDRVGHNEVIGVCR 468
+ R+LKK++T K+ +NPV+NE I+F++P + + S+ + V+ D G + +G C
Sbjct: 335 HQARKLKKKQTKRAKHKINPVWNEMIMFELPDDLLQASSVELEVLGQDDSGQSCALGHCS 394
Query: 469 TGLDAEGLGRDHWNEMLAYHRKPITHWHPL 498
GL G R HW EML R+ I WH L
Sbjct: 395 LGLHTSGSERSHWEEMLKNPRRQIAMWHQL 424
>gi|193804862 synaptotagmin-like 4 [Homo sapiens]
Length = 671
Score = 125 bits (314), Expect = 9e-29
Identities = 89/331 (26%), Positives = 162/331 (48%), Gaps = 32/331 (9%)
Query: 197 LQRGETTTSIGRIKPELYKQKSVDSEGNQNEDVKICGKLNFTLQYDYENELLVVKIIKAL 256
+Q G + ++IG + S+ SE ++ + G++ F+L+Y+ + + LVV + +
Sbjct: 329 MQSGSSMSTIGSMM-------SIYSEAGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECH 381
Query: 257 DLP-AKDFTGTSDPYVKMYLLPDRKK--KFQTRVHRKTLNPLFDETFQFPVAYDQLSNRK 313
L A + S+PYVK YLLPD+ + K +T + R T+NPL+DET ++ + L+ R
Sbjct: 382 QLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDETLRYEIPESLLAQRT 441
Query: 314 LHFSVYDFDRFSRHDMIG--EVILDNLFEVSDLSREATVWKDIHCATTESI--DLGEIMF 369
L FSV+ RF R+ +G E+ +D+ L + I + + GE++
Sbjct: 442 LQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPLHGKISAESPTGLPSHKGELVV 501
Query: 370 SLCYLPTA----------------GRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRR 413
SL Y+P + G + + + + +NL A G+SD +VK L+ +
Sbjct: 502 SLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNK 561
Query: 414 LKKRKTTTKKNTLNPVYNEAIIFD-IPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLD 472
KRKT K TLNP YN +++ + E++ + L + V D + + N+ +G R G+
Sbjct: 562 ASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLGV- 620
Query: 473 AEGLGRDHWNEMLAYHRKPITHWHPLLELPG 503
G+ + + + ++ W + + PG
Sbjct: 621 GTGISNGEVVDWMDSTGEEVSLWQKMRQYPG 651
>gi|193804860 synaptotagmin-like 4 [Homo sapiens]
Length = 671
Score = 125 bits (314), Expect = 9e-29
Identities = 89/331 (26%), Positives = 162/331 (48%), Gaps = 32/331 (9%)
Query: 197 LQRGETTTSIGRIKPELYKQKSVDSEGNQNEDVKICGKLNFTLQYDYENELLVVKIIKAL 256
+Q G + ++IG + S+ SE ++ + G++ F+L+Y+ + + LVV + +
Sbjct: 329 MQSGSSMSTIGSMM-------SIYSEAGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECH 381
Query: 257 DLP-AKDFTGTSDPYVKMYLLPDRKK--KFQTRVHRKTLNPLFDETFQFPVAYDQLSNRK 313
L A + S+PYVK YLLPD+ + K +T + R T+NPL+DET ++ + L+ R
Sbjct: 382 QLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDETLRYEIPESLLAQRT 441
Query: 314 LHFSVYDFDRFSRHDMIG--EVILDNLFEVSDLSREATVWKDIHCATTESI--DLGEIMF 369
L FSV+ RF R+ +G E+ +D+ L + I + + GE++
Sbjct: 442 LQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPLHGKISAESPTGLPSHKGELVV 501
Query: 370 SLCYLPTA----------------GRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRR 413
SL Y+P + G + + + + +NL A G+SD +VK L+ +
Sbjct: 502 SLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNK 561
Query: 414 LKKRKTTTKKNTLNPVYNEAIIFD-IPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLD 472
KRKT K TLNP YN +++ + E++ + L + V D + + N+ +G R G+
Sbjct: 562 ASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLGV- 620
Query: 473 AEGLGRDHWNEMLAYHRKPITHWHPLLELPG 503
G+ + + + ++ W + + PG
Sbjct: 621 GTGISNGEVVDWMDSTGEEVSLWQKMRQYPG 651
>gi|46255062 synaptotagmin-like 2 isoform c [Homo sapiens]
Length = 1272
Score = 115 bits (289), Expect = 7e-26
Identities = 110/423 (26%), Positives = 194/423 (45%), Gaps = 45/423 (10%)
Query: 85 KSKPVTSNITTLPQSISSAPTEVFETEEKKEIKENEKPAVKAIEPAIKISHTSPDIPAEV 144
KS S+ ++ + + P E+ + E E K ++KP P I T PD P
Sbjct: 832 KSLEDISSDSSNQAKVDNQPEELVRSAEDDE-KPDQKPVTNECVPRISTVPTQPDNPFSH 890
Query: 145 QTALKE--HLIKHARVQRQITEPTSSTRHSSFR--RHLPRQMQVSSVDFSMGTEPVLQRG 200
LK + T + SS++ RH ++++ S G
Sbjct: 891 PDKLKRMSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGM------- 943
Query: 201 ETTTSIGRIKPELYKQKSVDSEGNQNEDVKICGKLNFTLQYDYENELLVVKIIKALDLPA 260
TS+ + + S D GN +++ G + F ++Y + L V + + DL A
Sbjct: 944 ---TSLSSVSGSVMSVYSGDF-GN----LEVKGNIQFAIEYVESLKELHVFVAQCKDLAA 995
Query: 261 KDFTGT-SDPYVKMYLLPDRKK--KFQTRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFS 317
D SDPYVK YLLPD+ K K +T V +KTLNP+++E ++ + L +KL+ S
Sbjct: 996 ADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLS 1055
Query: 318 VYDFDRFSRHDMIGEVILD-NLFEVSDLSREATVWKDIHCATT----ESIDLGEIMFSLC 372
++ D F R+ +GEV LD ++ + + W + T E+ + GE+ +L
Sbjct: 1056 IWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQ 1115
Query: 373 Y---------LPTAGRMTLTVIKCRNLKAMDITGSS-DPYVKVSLMCEGRRLKKRKTTTK 422
Y LPT G + + V +C +L + GS + +VK +++ + R ++KT
Sbjct: 1116 YVPEPVPGKKLPTTGEVHIWVKECLDLPL--LRGSHLNSFVKCTILPDTSRKSRQKTRAV 1173
Query: 423 KNTLNPVYNEAIIFD-IPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLDAEGLGRDHW 481
T NP++N +++D PE++ + + + V D+ ++ N+ +G R G G G+ +
Sbjct: 1174 GKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGF---GTGKSYG 1229
Query: 482 NEM 484
E+
Sbjct: 1230 TEV 1232
>gi|226342962 synaptotagmin XIV isoform 2 [Homo sapiens]
Length = 600
Score = 115 bits (288), Expect = 1e-25
Identities = 81/297 (27%), Positives = 138/297 (46%), Gaps = 33/297 (11%)
Query: 233 GKLNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDRKKKFQTRVHRKTL 292
G L+ T YD + + L+V + D+P + TG + V + LLP +K++ +T + R
Sbjct: 307 GTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPC 366
Query: 293 NPLFDETFQFP-VAYDQLSNRKLHFSVYDFDRFSRHDMIGEVIL---------------- 335
P+F ETF+F V + + N + F +Y R + ++GE I
Sbjct: 367 -PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVI 425
Query: 336 ----------DNLFEVSDLSREATVWKDIHCATTESIDLGEIMFSLCYLPTAGRMTLTVI 385
D+ VS++S + C + E + EI+ L Y T GR++ VI
Sbjct: 426 LEPSYNHSGCDSQMSVSEMSCSESTSS---CQSLEHGSVPEILIGLLYNATTGRLSAEVI 482
Query: 386 KCRNLKAMDITGSSDPYVKVSLMCE-GRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVD 444
K + K + + YVK++L+ G+ + K KT+ ++ NPVY E +F + +
Sbjct: 483 KGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLS 542
Query: 445 QVSLSIAVMDYDRVGHNEVIGVCRTGLDAEGLGR-DHWNEMLAYHRKPITHWHPLLE 500
V+L ++V + + E+IG GL++ G +HW EM + + WH LLE
Sbjct: 543 DVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLE 599
>gi|144226225 synaptotagmin XIV isoform 4 [Homo sapiens]
Length = 555
Score = 115 bits (288), Expect = 1e-25
Identities = 81/297 (27%), Positives = 138/297 (46%), Gaps = 33/297 (11%)
Query: 233 GKLNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDRKKKFQTRVHRKTL 292
G L+ T YD + + L+V + D+P + TG + V + LLP +K++ +T + R
Sbjct: 262 GTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPC 321
Query: 293 NPLFDETFQFP-VAYDQLSNRKLHFSVYDFDRFSRHDMIGEVIL---------------- 335
P+F ETF+F V + + N + F +Y R + ++GE I
Sbjct: 322 -PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVI 380
Query: 336 ----------DNLFEVSDLSREATVWKDIHCATTESIDLGEIMFSLCYLPTAGRMTLTVI 385
D+ VS++S + C + E + EI+ L Y T GR++ VI
Sbjct: 381 LEPSYNHSGCDSQMSVSEMSCSESTSS---CQSLEHGSVPEILIGLLYNATTGRLSAEVI 437
Query: 386 KCRNLKAMDITGSSDPYVKVSLMCE-GRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVD 444
K + K + + YVK++L+ G+ + K KT+ ++ NPVY E +F + +
Sbjct: 438 KGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLS 497
Query: 445 QVSLSIAVMDYDRVGHNEVIGVCRTGLDAEGLGR-DHWNEMLAYHRKPITHWHPLLE 500
V+L ++V + + E+IG GL++ G +HW EM + + WH LLE
Sbjct: 498 DVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLE 554
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,323,091
Number of Sequences: 37866
Number of extensions: 906864
Number of successful extensions: 3793
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 128
Number of HSP's successfully gapped in prelim test: 64
Number of HSP's that attempted gapping in prelim test: 2887
Number of HSP's gapped (non-prelim): 581
length of query: 523
length of database: 18,247,518
effective HSP length: 107
effective length of query: 416
effective length of database: 14,195,856
effective search space: 5905476096
effective search space used: 5905476096
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.