Guide to the Human Genome
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Search of human proteins with 38045917

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38045917 phosphatidylinositol glycan anchor biosynthesis,
class O isoform 2 [Homo sapiens]
         (672 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38045917 phosphatidylinositol glycan anchor biosynthesis, cla...  1362   0.0  
gi|23397648 phosphatidylinositol glycan anchor biosynthesis, cla...   907   0.0  
gi|187608446 phosphatidylinositol glycan anchor biosynthesis, cl...   206   4e-53
gi|187608438 phosphatidylinositol glycan anchor biosynthesis, cl...   206   4e-53
gi|6912500 phosphatidylinositol glycan anchor biosynthesis, clas...    50   9e-06
gi|29029537 phosphatidylinositol glycan anchor biosynthesis, cla...    50   9e-06
gi|45545421 ectonucleotide pyrophosphatase/phosphodiesterase 7 [...    45   2e-04
gi|195947389 autotaxin isoform 3 preproprotein [Homo sapiens]          40   0.005
gi|91823602 autotaxin isoform 2 preproprotein [Homo sapiens]           40   0.005
gi|11034849 ectonucleotide pyrophosphatase/phosphodiesterase 5 (...    35   0.29 
gi|170650661 ectonucleotide pyrophosphatase/phosphodiesterase 1 ...    34   0.38 
gi|23503267 ectonucleotide pyrophosphatase/phosphodiesterase 6 [...    33   0.66 
gi|156104866 acyl-Coenzyme A oxidase 3 isoform b [Homo sapiens]        33   0.86 
gi|239755573 PREDICTED: similar to ectonucleotide pyrophosphatas...    32   1.5  
gi|156104864 acyl-Coenzyme A oxidase 3 isoform a [Homo sapiens]        32   1.9  
gi|53831991 steryl-sulfatase precursor [Homo sapiens]                  32   2.5  
gi|4557659 iduronate-2-sulfatase isoform a precursor [Homo sapiens]    32   2.5  
gi|132566680 scavenger receptor class B, member 1 isoform 2 [Hom...    30   5.5  
gi|84105335 mesenchyme homeobox 2 [Homo sapiens]                       30   7.2  
gi|28629866 Rho-related BTB domain containing 1 [Homo sapiens]         30   7.2  
gi|31881740 solute carrier family 12 (potassium/chloride transpo...    30   7.2  
gi|20162554 Kruppel-like factor 14 [Homo sapiens]                      30   9.5  
gi|219555736 zinc finger protein 438 isoform b [Homo sapiens]          30   9.5  
gi|219555734 zinc finger protein 438 isoform b [Homo sapiens]          30   9.5  
gi|219555732 zinc finger protein 438 isoform c [Homo sapiens]          30   9.5  
gi|219555729 zinc finger protein 438 isoform a [Homo sapiens]          30   9.5  
gi|219555727 zinc finger protein 438 isoform a [Homo sapiens]          30   9.5  
gi|219555725 zinc finger protein 438 isoform a [Homo sapiens]          30   9.5  
gi|33300651 zinc finger protein 438 isoform a [Homo sapiens]           30   9.5  
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]     30   9.5  

>gi|38045917 phosphatidylinositol glycan anchor biosynthesis, class
           O isoform 2 [Homo sapiens]
          Length = 672

 Score = 1362 bits (3524), Expect = 0.0
 Identities = 672/672 (100%), Positives = 672/672 (100%)

Query: 1   MQKASVLLFLAWVCFLFYAGIALFTSGFLLTRLELTNHSSCQEPPGPGSLPWGSQGKPGA 60
           MQKASVLLFLAWVCFLFYAGIALFTSGFLLTRLELTNHSSCQEPPGPGSLPWGSQGKPGA
Sbjct: 1   MQKASVLLFLAWVCFLFYAGIALFTSGFLLTRLELTNHSSCQEPPGPGSLPWGSQGKPGA 60

Query: 61  CWMASRFSRVVLVLIDALRFDFAQPQHSHVPREPPVSLPFLGKLSSLQRILEIQPHHARL 120
           CWMASRFSRVVLVLIDALRFDFAQPQHSHVPREPPVSLPFLGKLSSLQRILEIQPHHARL
Sbjct: 61  CWMASRFSRVVLVLIDALRFDFAQPQHSHVPREPPVSLPFLGKLSSLQRILEIQPHHARL 120

Query: 121 YRSQVDPPTTTMQRLKALTTGSLPTFIDAGSNFASHAIVEDNLIKQLTSAGRRVVFMGDD 180
           YRSQVDPPTTTMQRLKALTTGSLPTFIDAGSNFASHAIVEDNLIKQLTSAGRRVVFMGDD
Sbjct: 121 YRSQVDPPTTTMQRLKALTTGSLPTFIDAGSNFASHAIVEDNLIKQLTSAGRRVVFMGDD 180

Query: 181 TWKDLFPGAFSKAFFFPSFNVRDLDTVDNGILEHLYPTMDSGEWDVLIAHFLGVDHCGHK 240
           TWKDLFPGAFSKAFFFPSFNVRDLDTVDNGILEHLYPTMDSGEWDVLIAHFLGVDHCGHK
Sbjct: 181 TWKDLFPGAFSKAFFFPSFNVRDLDTVDNGILEHLYPTMDSGEWDVLIAHFLGVDHCGHK 240

Query: 241 HGPHHPEMAKKLSQMDQVIQGLVERLENDTLLVVAGDHGMTTNGDHGGDSELEVSAALFL 300
           HGPHHPEMAKKLSQMDQVIQGLVERLENDTLLVVAGDHGMTTNGDHGGDSELEVSAALFL
Sbjct: 241 HGPHHPEMAKKLSQMDQVIQGLVERLENDTLLVVAGDHGMTTNGDHGGDSELEVSAALFL 300

Query: 301 YSPTAVFPSTPPEEPEVIPQVSLVPTLALLLGLPIPFGNIGEVMAELFSGGEDSQPHSSA 360
           YSPTAVFPSTPPEEPEVIPQVSLVPTLALLLGLPIPFGNIGEVMAELFSGGEDSQPHSSA
Sbjct: 301 YSPTAVFPSTPPEEPEVIPQVSLVPTLALLLGLPIPFGNIGEVMAELFSGGEDSQPHSSA 360

Query: 361 LAQASALHLNAQQVSRFLHTYSAATQDLQAKELHQLQNLFSKASADYQWLLQSPKGAEAT 420
           LAQASALHLNAQQVSRFLHTYSAATQDLQAKELHQLQNLFSKASADYQWLLQSPKGAEAT
Sbjct: 361 LAQASALHLNAQQVSRFLHTYSAATQDLQAKELHQLQNLFSKASADYQWLLQSPKGAEAT 420

Query: 421 LPTVIAELQQFLRGARAMCIESWARFSLSFLLLHLLAAGIPVTTPGPFTVPWQAVSAWAL 480
           LPTVIAELQQFLRGARAMCIESWARFSLSFLLLHLLAAGIPVTTPGPFTVPWQAVSAWAL
Sbjct: 421 LPTVIAELQQFLRGARAMCIESWARFSLSFLLLHLLAAGIPVTTPGPFTVPWQAVSAWAL 480

Query: 481 MATQTFYSTGHQPVFPAIHWHAAFVGFPEGHGSCTWLPALLVGANTFASHLLFAVGCPLL 540
           MATQTFYSTGHQPVFPAIHWHAAFVGFPEGHGSCTWLPALLVGANTFASHLLFAVGCPLL
Sbjct: 481 MATQTFYSTGHQPVFPAIHWHAAFVGFPEGHGSCTWLPALLVGANTFASHLLFAVGCPLL 540

Query: 541 LLWPFLCESQGLRKRQQPPGNEADARVRPEEEEEPLMEMRLRDAPQHFYAALLQLGLKYL 600
           LLWPFLCESQGLRKRQQPPGNEADARVRPEEEEEPLMEMRLRDAPQHFYAALLQLGLKYL
Sbjct: 541 LLWPFLCESQGLRKRQQPPGNEADARVRPEEEEEPLMEMRLRDAPQHFYAALLQLGLKYL 600

Query: 601 FILGIQILACALAASILRRHLMVWKVFAPKFIFEAVGFIVSSVGLLLGIALVMRVDGAVS 660
           FILGIQILACALAASILRRHLMVWKVFAPKFIFEAVGFIVSSVGLLLGIALVMRVDGAVS
Sbjct: 601 FILGIQILACALAASILRRHLMVWKVFAPKFIFEAVGFIVSSVGLLLGIALVMRVDGAVS 660

Query: 661 SWFRQLFLAQQR 672
           SWFRQLFLAQQR
Sbjct: 661 SWFRQLFLAQQR 672


>gi|23397648 phosphatidylinositol glycan anchor biosynthesis, class
           O isoform 1 [Homo sapiens]
          Length = 1089

 Score =  907 bits (2344), Expect = 0.0
 Identities = 448/448 (100%), Positives = 448/448 (100%)

Query: 1   MQKASVLLFLAWVCFLFYAGIALFTSGFLLTRLELTNHSSCQEPPGPGSLPWGSQGKPGA 60
           MQKASVLLFLAWVCFLFYAGIALFTSGFLLTRLELTNHSSCQEPPGPGSLPWGSQGKPGA
Sbjct: 1   MQKASVLLFLAWVCFLFYAGIALFTSGFLLTRLELTNHSSCQEPPGPGSLPWGSQGKPGA 60

Query: 61  CWMASRFSRVVLVLIDALRFDFAQPQHSHVPREPPVSLPFLGKLSSLQRILEIQPHHARL 120
           CWMASRFSRVVLVLIDALRFDFAQPQHSHVPREPPVSLPFLGKLSSLQRILEIQPHHARL
Sbjct: 61  CWMASRFSRVVLVLIDALRFDFAQPQHSHVPREPPVSLPFLGKLSSLQRILEIQPHHARL 120

Query: 121 YRSQVDPPTTTMQRLKALTTGSLPTFIDAGSNFASHAIVEDNLIKQLTSAGRRVVFMGDD 180
           YRSQVDPPTTTMQRLKALTTGSLPTFIDAGSNFASHAIVEDNLIKQLTSAGRRVVFMGDD
Sbjct: 121 YRSQVDPPTTTMQRLKALTTGSLPTFIDAGSNFASHAIVEDNLIKQLTSAGRRVVFMGDD 180

Query: 181 TWKDLFPGAFSKAFFFPSFNVRDLDTVDNGILEHLYPTMDSGEWDVLIAHFLGVDHCGHK 240
           TWKDLFPGAFSKAFFFPSFNVRDLDTVDNGILEHLYPTMDSGEWDVLIAHFLGVDHCGHK
Sbjct: 181 TWKDLFPGAFSKAFFFPSFNVRDLDTVDNGILEHLYPTMDSGEWDVLIAHFLGVDHCGHK 240

Query: 241 HGPHHPEMAKKLSQMDQVIQGLVERLENDTLLVVAGDHGMTTNGDHGGDSELEVSAALFL 300
           HGPHHPEMAKKLSQMDQVIQGLVERLENDTLLVVAGDHGMTTNGDHGGDSELEVSAALFL
Sbjct: 241 HGPHHPEMAKKLSQMDQVIQGLVERLENDTLLVVAGDHGMTTNGDHGGDSELEVSAALFL 300

Query: 301 YSPTAVFPSTPPEEPEVIPQVSLVPTLALLLGLPIPFGNIGEVMAELFSGGEDSQPHSSA 360
           YSPTAVFPSTPPEEPEVIPQVSLVPTLALLLGLPIPFGNIGEVMAELFSGGEDSQPHSSA
Sbjct: 301 YSPTAVFPSTPPEEPEVIPQVSLVPTLALLLGLPIPFGNIGEVMAELFSGGEDSQPHSSA 360

Query: 361 LAQASALHLNAQQVSRFLHTYSAATQDLQAKELHQLQNLFSKASADYQWLLQSPKGAEAT 420
           LAQASALHLNAQQVSRFLHTYSAATQDLQAKELHQLQNLFSKASADYQWLLQSPKGAEAT
Sbjct: 361 LAQASALHLNAQQVSRFLHTYSAATQDLQAKELHQLQNLFSKASADYQWLLQSPKGAEAT 420

Query: 421 LPTVIAELQQFLRGARAMCIESWARFSL 448
           LPTVIAELQQFLRGARAMCIESWARFSL
Sbjct: 421 LPTVIAELQQFLRGARAMCIESWARFSL 448



 Score =  459 bits (1182), Expect = e-129
 Identities = 225/227 (99%), Positives = 225/227 (99%)

Query: 446  FSLSFLLLHLLAAGIPVTTPGPFTVPWQAVSAWALMATQTFYSTGHQPVFPAIHWHAAFV 505
            F  SFLLLHLLAAGIPVTTPGPFTVPWQAVSAWALMATQTFYSTGHQPVFPAIHWHAAFV
Sbjct: 863  FLQSFLLLHLLAAGIPVTTPGPFTVPWQAVSAWALMATQTFYSTGHQPVFPAIHWHAAFV 922

Query: 506  GFPEGHGSCTWLPALLVGANTFASHLLFAVGCPLLLLWPFLCESQGLRKRQQPPGNEADA 565
            GFPEGHGSCTWLPALLVGANTFASHLLFAVGCPLLLLWPFLCESQGLRKRQQPPGNEADA
Sbjct: 923  GFPEGHGSCTWLPALLVGANTFASHLLFAVGCPLLLLWPFLCESQGLRKRQQPPGNEADA 982

Query: 566  RVRPEEEEEPLMEMRLRDAPQHFYAALLQLGLKYLFILGIQILACALAASILRRHLMVWK 625
            RVRPEEEEEPLMEMRLRDAPQHFYAALLQLGLKYLFILGIQILACALAASILRRHLMVWK
Sbjct: 983  RVRPEEEEEPLMEMRLRDAPQHFYAALLQLGLKYLFILGIQILACALAASILRRHLMVWK 1042

Query: 626  VFAPKFIFEAVGFIVSSVGLLLGIALVMRVDGAVSSWFRQLFLAQQR 672
            VFAPKFIFEAVGFIVSSVGLLLGIALVMRVDGAVSSWFRQLFLAQQR
Sbjct: 1043 VFAPKFIFEAVGFIVSSVGLLLGIALVMRVDGAVSSWFRQLFLAQQR 1089


>gi|187608446 phosphatidylinositol glycan anchor biosynthesis, class
           G isoform 1 [Homo sapiens]
          Length = 983

 Score =  206 bits (525), Expect = 4e-53
 Identities = 135/374 (36%), Positives = 191/374 (51%), Gaps = 45/374 (12%)

Query: 20  GIALFTSGFL------LTRLELTNHSSCQEPPGPGSLPWGSQGKPGACWMASRFSRVVLV 73
           GIA+F  GF         R E        EP    S  W +   P        FS+VV+V
Sbjct: 19  GIAVFLRGFFPAPVRSSARAEHGAEPPAPEPSAGASSNWTTLPPP-------LFSKVVIV 71

Query: 74  LIDALRFDFAQPQHSHVPREPPVSLPFLGKLSSLQRILEIQPHHARLYRSQVDPPTTTMQ 133
           LIDALR DF               + F+   + L     ++   +  + ++  PPT TM 
Sbjct: 72  LIDALRDDFVFGSKG---------VKFMPYTTYL-----VEKGASHSFVAEAKPPTVTMP 117

Query: 134 RLKALTTGSLPTFIDAGSNFASHAIVEDNLIKQLTSAGRRVVFMGDDTWKDLFPGAFSKA 193
           R+KAL TGSLP F+D   N  S A++ED++I+Q  +AG+R+VF GD+TW  LFP  F + 
Sbjct: 118 RIKALMTGSLPGFVDVIRNLNSPALLEDSVIRQAKAAGKRIVFYGDETWVKLFPKHFVEY 177

Query: 194 FFFPSFNVRDLDTVDNGILEHLYPTMDSGEWDVLIAHFLGVDHCGHKHGPHHPEMAKKLS 253
               SF V D   VDN +  HL   +  G+WD+LI H+LG+DH GH  GP+ P + +KLS
Sbjct: 178 DGTTSFFVSDYTEVDNNVTRHLDKVLKRGDWDILILHYLGLDHIGHISGPNSPLIGQKLS 237

Query: 254 QMDQVIQGLVERLEN-------DTLLVVAGDHGMTTNGDHGGDSELEVSAALFLYSPTAV 306
           +MD V+  +   L++         LLV+ GDHGM+  G HG  S  EV+  L L S  + 
Sbjct: 238 EMDSVLMKIHTSLQSKERETPLPNLLVLCGDHGMSETGSHGASSTEEVNTPLILIS--SA 295

Query: 307 FPSTPPE--EPEVIPQVSLVPTLALLLGLPIPFGNIGEVMAELFSGGEDSQPHSSALAQA 364
           F   P +   P+ + Q  +  TLA+ LGLPIP  ++G ++  +  G    +       Q 
Sbjct: 296 FERKPGDIRHPKHVQQTDVAATLAIALGLPIPKDSVGSLLFPVVEGRPMRE-------QL 348

Query: 365 SALHLNAQQVSRFL 378
             LHLN  Q+S+ L
Sbjct: 349 RFLHLNTVQLSKLL 362



 Score = 36.6 bits (83), Expect = 0.077
 Identities = 13/44 (29%), Positives = 25/44 (56%)

Query: 599 YLFILGIQILACALAASILRRHLMVWKVFAPKFIFEAVGFIVSS 642
           Y  I  I +    +  + LR HL +W VF+PK ++E +  ++++
Sbjct: 923 YALICSIPVFTYIVLVTSLRYHLFIWSVFSPKLLYEGMHLLITA 966


>gi|187608438 phosphatidylinositol glycan anchor biosynthesis, class
           G isoform 2 [Homo sapiens]
          Length = 975

 Score =  206 bits (525), Expect = 4e-53
 Identities = 135/374 (36%), Positives = 191/374 (51%), Gaps = 45/374 (12%)

Query: 20  GIALFTSGFL------LTRLELTNHSSCQEPPGPGSLPWGSQGKPGACWMASRFSRVVLV 73
           GIA+F  GF         R E        EP    S  W +   P        FS+VV+V
Sbjct: 19  GIAVFLRGFFPAPVRSSARAEHGAEPPAPEPSAGASSNWTTLPPP-------LFSKVVIV 71

Query: 74  LIDALRFDFAQPQHSHVPREPPVSLPFLGKLSSLQRILEIQPHHARLYRSQVDPPTTTMQ 133
           LIDALR DF               + F+   + L     ++   +  + ++  PPT TM 
Sbjct: 72  LIDALRDDFVFGSKG---------VKFMPYTTYL-----VEKGASHSFVAEAKPPTVTMP 117

Query: 134 RLKALTTGSLPTFIDAGSNFASHAIVEDNLIKQLTSAGRRVVFMGDDTWKDLFPGAFSKA 193
           R+KAL TGSLP F+D   N  S A++ED++I+Q  +AG+R+VF GD+TW  LFP  F + 
Sbjct: 118 RIKALMTGSLPGFVDVIRNLNSPALLEDSVIRQAKAAGKRIVFYGDETWVKLFPKHFVEY 177

Query: 194 FFFPSFNVRDLDTVDNGILEHLYPTMDSGEWDVLIAHFLGVDHCGHKHGPHHPEMAKKLS 253
               SF V D   VDN +  HL   +  G+WD+LI H+LG+DH GH  GP+ P + +KLS
Sbjct: 178 DGTTSFFVSDYTEVDNNVTRHLDKVLKRGDWDILILHYLGLDHIGHISGPNSPLIGQKLS 237

Query: 254 QMDQVIQGLVERLEN-------DTLLVVAGDHGMTTNGDHGGDSELEVSAALFLYSPTAV 306
           +MD V+  +   L++         LLV+ GDHGM+  G HG  S  EV+  L L S  + 
Sbjct: 238 EMDSVLMKIHTSLQSKERETPLPNLLVLCGDHGMSETGSHGASSTEEVNTPLILIS--SA 295

Query: 307 FPSTPPE--EPEVIPQVSLVPTLALLLGLPIPFGNIGEVMAELFSGGEDSQPHSSALAQA 364
           F   P +   P+ + Q  +  TLA+ LGLPIP  ++G ++  +  G    +       Q 
Sbjct: 296 FERKPGDIRHPKHVQQTDVAATLAIALGLPIPKDSVGSLLFPVVEGRPMRE-------QL 348

Query: 365 SALHLNAQQVSRFL 378
             LHLN  Q+S+ L
Sbjct: 349 RFLHLNTVQLSKLL 362



 Score = 36.6 bits (83), Expect = 0.077
 Identities = 13/44 (29%), Positives = 25/44 (56%)

Query: 599 YLFILGIQILACALAASILRRHLMVWKVFAPKFIFEAVGFIVSS 642
           Y  I  I +    +  + LR HL +W VF+PK ++E +  ++++
Sbjct: 915 YALICSIPVFTYIVLVTSLRYHLFIWSVFSPKLLYEGMHLLITA 958


>gi|6912500 phosphatidylinositol glycan anchor biosynthesis, class N
           [Homo sapiens]
          Length = 931

 Score = 49.7 bits (117), Expect = 9e-06
 Identities = 35/171 (20%), Positives = 64/171 (37%), Gaps = 30/171 (17%)

Query: 226 VLIAHFLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLVERL------ENDTLLVVAGDHG 279
           V   H LG+D  GH H P   +    + ++D  ++ +V         +  T  +   DHG
Sbjct: 205 VFFLHLLGIDTNGHAHRPSSRDYKHNIKKVDDGVKEIVSMFNHFYGNDGKTTFIFTSDHG 264

Query: 280 MTTNGDHGGDSELEVSAALFLYSPTAVFPSTPPEEP----------------EVIPQVSL 323
           MT  G HG     E    L  +     +P     +                   + Q  +
Sbjct: 265 MTDWGSHGAGHPSETLTPLVTWGAGIKYPQRVSAQQFDDAFLKEWRLENWKRLDVNQADI 324

Query: 324 VPTLALLLGLPIPFGNIGEVMAELFSGGEDSQPHSSALAQASALHLNAQQV 374
            P +  L+G+P P  ++G +  +          +++ L +A ++  NA Q+
Sbjct: 325 APLMTSLIGVPFPLNSVGILPVDYL--------NNTDLFKAESMFTNAVQI 367


>gi|29029537 phosphatidylinositol glycan anchor biosynthesis, class
           N [Homo sapiens]
          Length = 931

 Score = 49.7 bits (117), Expect = 9e-06
 Identities = 35/171 (20%), Positives = 64/171 (37%), Gaps = 30/171 (17%)

Query: 226 VLIAHFLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLVERL------ENDTLLVVAGDHG 279
           V   H LG+D  GH H P   +    + ++D  ++ +V         +  T  +   DHG
Sbjct: 205 VFFLHLLGIDTNGHAHRPSSRDYKHNIKKVDDGVKEIVSMFNHFYGNDGKTTFIFTSDHG 264

Query: 280 MTTNGDHGGDSELEVSAALFLYSPTAVFPSTPPEEP----------------EVIPQVSL 323
           MT  G HG     E    L  +     +P     +                   + Q  +
Sbjct: 265 MTDWGSHGAGHPSETLTPLVTWGAGIKYPQRVSAQQFDDAFLKEWRLENWKRLDVNQADI 324

Query: 324 VPTLALLLGLPIPFGNIGEVMAELFSGGEDSQPHSSALAQASALHLNAQQV 374
            P +  L+G+P P  ++G +  +          +++ L +A ++  NA Q+
Sbjct: 325 APLMTSLIGVPFPLNSVGILPVDYL--------NNTDLFKAESMFTNAVQI 367


>gi|45545421 ectonucleotide pyrophosphatase/phosphodiesterase 7
           [Homo sapiens]
          Length = 458

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 5/70 (7%)

Query: 225 DVLIAHFLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLENDTL-----LVVAGDHG 279
           D++  +F   D  GH++GP  PE  + + Q+D+ +  L E +  + L     L++  DHG
Sbjct: 189 DLVTLYFGEPDSTGHRYGPESPERREMVRQVDRTVGYLRESIARNHLTDRLNLIITSDHG 248

Query: 280 MTTNGDHGGD 289
           MTT     GD
Sbjct: 249 MTTVDKRAGD 258


>gi|195947389 autotaxin isoform 3 preproprotein [Homo sapiens]
          Length = 888

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 19/51 (37%), Positives = 30/51 (58%), Gaps = 5/51 (9%)

Query: 235 DHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLENDTL-----LVVAGDHGM 280
           D  GHK+GP  PEM   L ++D+++  L++ L+   L     ++  GDHGM
Sbjct: 312 DFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGM 362


>gi|91823602 autotaxin isoform 2 preproprotein [Homo sapiens]
          Length = 863

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 19/51 (37%), Positives = 30/51 (58%), Gaps = 5/51 (9%)

Query: 235 DHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLENDTL-----LVVAGDHGM 280
           D  GHK+GP  PEM   L ++D+++  L++ L+   L     ++  GDHGM
Sbjct: 312 DFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGM 362


>gi|11034849 ectonucleotide pyrophosphatase/phosphodiesterase 5
           (putative function) [Homo sapiens]
          Length = 477

 Score = 34.7 bits (78), Expect = 0.29
 Identities = 18/52 (34%), Positives = 27/52 (51%), Gaps = 5/52 (9%)

Query: 235 DHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLE-----NDTLLVVAGDHGMT 281
           D  GH  GP  P M   +S +D+ +  L++ L+     N   L++  DHGMT
Sbjct: 191 DDMGHHLGPDSPLMGPVISDIDKKLGYLIQMLKKAKLWNTLNLIITSDHGMT 242


>gi|170650661 ectonucleotide pyrophosphatase/phosphodiesterase 1
           [Homo sapiens]
          Length = 925

 Score = 34.3 bits (77), Expect = 0.38
 Identities = 43/188 (22%), Positives = 71/188 (37%), Gaps = 49/188 (26%)

Query: 128 PTTTMQRLKALTTGSLPTFIDAGSNFASHAIVEDNLIKQLTSAGRRVV---------FMG 178
           PT T     ++ TG  P          SH I+++ +     +A   +          + G
Sbjct: 253 PTKTFPNHYSIVTGLYPE---------SHGIIDNKMYDPKMNASFSLKSKEKFNPEWYKG 303

Query: 179 DDTWKDL-FPGAFSKAFFFPSFNVRDLDTVDNGILEHLYPTMDSG-----------EWDV 226
           +  W    + G  S  FF+P  +V       NGI   +Y   +             +W  
Sbjct: 304 EPIWVTAKYQGLKSGTFFWPGSDVEI-----NGIFPDIYKMYNGSVPFEERILAVLQWLQ 358

Query: 227 LIA----HFLGV-----DHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLENDTL-----L 272
           L      HF  +     D  GH +GP   E+ K L ++D ++  L++ L+   L     L
Sbjct: 359 LPKDERPHFYTLYLEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKELNLHRCLNL 418

Query: 273 VVAGDHGM 280
           ++  DHGM
Sbjct: 419 ILISDHGM 426


>gi|23503267 ectonucleotide pyrophosphatase/phosphodiesterase 6
           [Homo sapiens]
          Length = 440

 Score = 33.5 bits (75), Expect = 0.66
 Identities = 18/66 (27%), Positives = 33/66 (50%), Gaps = 5/66 (7%)

Query: 221 SGEWDVLIAHFLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLENDTL-----LVVA 275
           SG  D+   +   +D  GH +GP  P+    L  +D V++ + + ++   L     +++ 
Sbjct: 179 SGRADLAAIYHERIDVEGHHYGPASPQRKDALKAVDTVLKYMTKWIQERGLQDRLNVIIF 238

Query: 276 GDHGMT 281
            DHGMT
Sbjct: 239 SDHGMT 244


>gi|156104866 acyl-Coenzyme A oxidase 3 isoform b [Homo sapiens]
          Length = 624

 Score = 33.1 bits (74), Expect = 0.86
 Identities = 15/39 (38%), Positives = 22/39 (56%)

Query: 86  QHSHVPREPPVSLPFLGKLSSLQRILEIQPHHARLYRSQ 124
           +H H P  PP     LG+LS+L  +  +  H A LYR++
Sbjct: 573 EHVHQPSVPPSLRAVLGRLSALYALWSLSRHAALLYRAE 611


>gi|239755573 PREDICTED: similar to ectonucleotide
           pyrophosphatase/phosphodiesterase 5 (putative function)
           [Homo sapiens]
          Length = 661

 Score = 32.3 bits (72), Expect = 1.5
 Identities = 17/64 (26%), Positives = 31/64 (48%), Gaps = 4/64 (6%)

Query: 223 EWDVLIAHFLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLENDTL----LVVAGDH 278
           ++D +  ++   D+ GH+  P        + Q+D+ I  LV   E  +L    +++  DH
Sbjct: 278 DFDFVTLYYRQPDNVGHRFKPEAENRKLMIQQLDRTIWYLVGATEKHSLQSPQVIITXDH 337

Query: 279 GMTT 282
           GM T
Sbjct: 338 GMMT 341


>gi|156104864 acyl-Coenzyme A oxidase 3 isoform a [Homo sapiens]
          Length = 700

 Score = 32.0 bits (71), Expect = 1.9
 Identities = 15/37 (40%), Positives = 20/37 (54%)

Query: 86  QHSHVPREPPVSLPFLGKLSSLQRILEIQPHHARLYR 122
           +H H P  PP     LG+LS+L  +  +  H A LYR
Sbjct: 573 EHVHQPSVPPSLRAVLGRLSALYALWSLSRHAALLYR 609


>gi|53831991 steryl-sulfatase precursor [Homo sapiens]
          Length = 583

 Score = 31.6 bits (70), Expect = 2.5
 Identities = 42/164 (25%), Positives = 65/164 (39%), Gaps = 24/164 (14%)

Query: 229 AHFLGVDHCGH-KHGPHHPEMAKKLSQMDQVIQGLVE-RLENDTLLVVAGDHG-----MT 281
           A F   D  G  +HG +   + +    + Q++  L E RL NDTL+    D G     ++
Sbjct: 292 ALFSSKDFAGKSQHGVYGDAVEEMDWSVGQILNLLDELRLANDTLIYFTSDQGAHVEEVS 351

Query: 282 TNGD-HGGDS-----------ELEVSAALFLYSPTAVFPSTPPEEPEVIPQVSLVPTLAL 329
           + G+ HGG +           E  +     L  P  +      +EP     + + PT+A 
Sbjct: 352 SKGEIHGGSNGIYKGGKANNWEGGIRVPGILRWPRVIQAGQKIDEPT--SNMDIFPTVAK 409

Query: 330 LLGLPIPFGNI--GEVMAELFSGGEDSQPHSSALAQASALHLNA 371
           L G P+P   I  G  +  L  G      H       +A +LNA
Sbjct: 410 LAGAPLPEDRIIDGRDLMPLLEGKSQRSDHEFLFHYCNA-YLNA 452


>gi|4557659 iduronate-2-sulfatase isoform a precursor [Homo sapiens]
          Length = 550

 Score = 31.6 bits (70), Expect = 2.5
 Identities = 29/117 (24%), Positives = 47/117 (40%), Gaps = 34/117 (29%)

Query: 247 EMAKKLSQMDQVIQGLVERLENDTLLVVAGDHGMTTNGDHG-----GDSELEVSAALFLY 301
           ++ + LS +D +      +L N T++    DHG    G+HG      + ++     L  Y
Sbjct: 310 QVGRLLSALDDL------QLANSTIIAFTSDHGWAL-GEHGEWAKYSNFDVATHVPLIFY 362

Query: 302 SP----------TAVFPSTPP------------EEPEVIPQVSLVPTLALLLGLPIP 336
            P            +FP   P            +  +++  VSL PTLA L GL +P
Sbjct: 363 VPGRTASLPEAGEKLFPYLDPFDSASQLMEPGRQSMDLVELVSLFPTLAGLAGLQVP 419


>gi|132566680 scavenger receptor class B, member 1 isoform 2 [Homo
           sapiens]
          Length = 506

 Score = 30.4 bits (67), Expect = 5.5
 Identities = 29/90 (32%), Positives = 42/90 (46%), Gaps = 7/90 (7%)

Query: 492 QPVFPAIHWHAAFVGFPEGHGSCTWLPALLVGANT--FASHLLFAVGCPLLLLWPFLCE- 548
           +PV   + W A   G  EG    T+   L++      +A ++L A+GC LLL+ P +C+ 
Sbjct: 407 EPVVLPLLWFAES-GAMEGETLHTFYTQLVLMPKVMHYAQYVLLALGCVLLLV-PVICQI 464

Query: 549 -SQGLRKRQQPPGNEADARVRPEEEEEPLM 577
            SQG       PG  A    RP     PL+
Sbjct: 465 RSQGPEDTVSQPGLAAGPD-RPPSPYTPLL 493


>gi|84105335 mesenchyme homeobox 2 [Homo sapiens]
          Length = 304

 Score = 30.0 bits (66), Expect = 7.2
 Identities = 28/111 (25%), Positives = 42/111 (37%), Gaps = 9/111 (8%)

Query: 209 NGILEHL-YPTMDSGEWDVLIAH-------FLGVDHCGHKHGPHHPEMAKKLSQMDQVIQ 260
           +G  +H+ YP + +     +IA        F    H GH H  HH        Q  Q +Q
Sbjct: 30  HGRSDHMSYPELSTSSSSCIIAGYPNEEGMFASQHHRGHHHHHHHHHHHHHQQQQHQALQ 89

Query: 261 GLVERLENDTLLVVAGDHGMTTNGDHGGDSELEVSAALFLYSPTAVFPSTP 311
                L   +    A  H +    D GG  EL  S  +   + +++  STP
Sbjct: 90  -TNWHLPQMSSPPSAARHSLCLQPDSGGPPELGSSPPVLCSNSSSLGSSTP 139


>gi|28629866 Rho-related BTB domain containing 1 [Homo sapiens]
          Length = 696

 Score = 30.0 bits (66), Expect = 7.2
 Identities = 35/125 (28%), Positives = 48/125 (38%), Gaps = 23/125 (18%)

Query: 501 HAAFVGFPEGHGSCTWLPALLVGANTFASHLLFAVGCPLLLLWPFLCESQGLRKRQQPPG 560
           H   + +PE    C   P +LVG             C L L +  L      R+    P 
Sbjct: 117 HVKSMWYPEIKHFCPRTPVILVG-------------CQLDLRYADLEAVNRARRPLARPI 163

Query: 561 NEADARVRPEEEEEPLMEMRLRDAPQHFYAALLQLGLKYLFILGIQILACALAASILRRH 620
              D  + PE+  E   E+ L   P +  +   Q G+K +F   I+      AA I RRH
Sbjct: 164 KRGDI-LPPEKGREVAKELGL---PYYETSVFDQFGIKDVFDNAIR------AALISRRH 213

Query: 621 LMVWK 625
           L  WK
Sbjct: 214 LQFWK 218


>gi|31881740 solute carrier family 12 (potassium/chloride
           transporters), member 9 [Homo sapiens]
          Length = 914

 Score = 30.0 bits (66), Expect = 7.2
 Identities = 19/50 (38%), Positives = 27/50 (54%), Gaps = 7/50 (14%)

Query: 284 GDHGGDSELEVSAALFLYSPTAVFPSTPPEEPEVIPQ-VSLVPTLALLLG 332
           G  GGD+E  ++A  FLY P       PP +P   P+ ++L+ TL   LG
Sbjct: 855 GPEGGDAEGPITALTFLYLP------RPPADPARYPRYLALLETLTRDLG 898


>gi|20162554 Kruppel-like factor 14 [Homo sapiens]
          Length = 323

 Score = 29.6 bits (65), Expect = 9.5
 Identities = 26/81 (32%), Positives = 35/81 (43%), Gaps = 5/81 (6%)

Query: 287 GGDSELEVSAALFLYSPTAVFPSTPPEEPEVIPQVSLVPTLALLLGLPIPFGNIGEVMAE 346
           GG +  EV AA     P +  P   P  P  +PQ+  VP  +   G   P      V A+
Sbjct: 36  GGAAGSEVGAA----HPESALPGPGPSGPASVPQLPQVPAPSPGAGGAAPHLLAASVWAD 91

Query: 347 L-FSGGEDSQPHSSALAQASA 366
           L  S GE S  +S    +AS+
Sbjct: 92  LRGSSGEGSWENSGEAPRASS 112


>gi|219555736 zinc finger protein 438 isoform b [Homo sapiens]
          Length = 818

 Score = 29.6 bits (65), Expect = 9.5
 Identities = 23/73 (31%), Positives = 30/73 (41%), Gaps = 8/73 (10%)

Query: 243 PHHPEMAKKLSQMDQVIQGLVERLENDTLLVVAGDHGMTTNGDHGGDSELEVSAALFLYS 302
           PHHPE+  K S  ++V       LE     +        TNG   GD    V+      +
Sbjct: 154 PHHPELLYKPSPFEEV-----PSLEQAPASISTA---ALTNGSDHGDLRPPVTNTHGSLN 205

Query: 303 PTAVFPSTPPEEP 315
           P A   S+ PEEP
Sbjct: 206 PPATPASSTPEEP 218


>gi|219555734 zinc finger protein 438 isoform b [Homo sapiens]
          Length = 818

 Score = 29.6 bits (65), Expect = 9.5
 Identities = 23/73 (31%), Positives = 30/73 (41%), Gaps = 8/73 (10%)

Query: 243 PHHPEMAKKLSQMDQVIQGLVERLENDTLLVVAGDHGMTTNGDHGGDSELEVSAALFLYS 302
           PHHPE+  K S  ++V       LE     +        TNG   GD    V+      +
Sbjct: 154 PHHPELLYKPSPFEEV-----PSLEQAPASISTA---ALTNGSDHGDLRPPVTNTHGSLN 205

Query: 303 PTAVFPSTPPEEP 315
           P A   S+ PEEP
Sbjct: 206 PPATPASSTPEEP 218


>gi|219555732 zinc finger protein 438 isoform c [Homo sapiens]
          Length = 779

 Score = 29.6 bits (65), Expect = 9.5
 Identities = 23/73 (31%), Positives = 30/73 (41%), Gaps = 8/73 (10%)

Query: 243 PHHPEMAKKLSQMDQVIQGLVERLENDTLLVVAGDHGMTTNGDHGGDSELEVSAALFLYS 302
           PHHPE+  K S  ++V       LE     +        TNG   GD    V+      +
Sbjct: 115 PHHPELLYKPSPFEEV-----PSLEQAPASISTA---ALTNGSDHGDLRPPVTNTHGSLN 166

Query: 303 PTAVFPSTPPEEP 315
           P A   S+ PEEP
Sbjct: 167 PPATPASSTPEEP 179


>gi|219555729 zinc finger protein 438 isoform a [Homo sapiens]
          Length = 828

 Score = 29.6 bits (65), Expect = 9.5
 Identities = 23/73 (31%), Positives = 30/73 (41%), Gaps = 8/73 (10%)

Query: 243 PHHPEMAKKLSQMDQVIQGLVERLENDTLLVVAGDHGMTTNGDHGGDSELEVSAALFLYS 302
           PHHPE+  K S  ++V       LE     +        TNG   GD    V+      +
Sbjct: 164 PHHPELLYKPSPFEEV-----PSLEQAPASISTA---ALTNGSDHGDLRPPVTNTHGSLN 215

Query: 303 PTAVFPSTPPEEP 315
           P A   S+ PEEP
Sbjct: 216 PPATPASSTPEEP 228


>gi|219555727 zinc finger protein 438 isoform a [Homo sapiens]
          Length = 828

 Score = 29.6 bits (65), Expect = 9.5
 Identities = 23/73 (31%), Positives = 30/73 (41%), Gaps = 8/73 (10%)

Query: 243 PHHPEMAKKLSQMDQVIQGLVERLENDTLLVVAGDHGMTTNGDHGGDSELEVSAALFLYS 302
           PHHPE+  K S  ++V       LE     +        TNG   GD    V+      +
Sbjct: 164 PHHPELLYKPSPFEEV-----PSLEQAPASISTA---ALTNGSDHGDLRPPVTNTHGSLN 215

Query: 303 PTAVFPSTPPEEP 315
           P A   S+ PEEP
Sbjct: 216 PPATPASSTPEEP 228


>gi|219555725 zinc finger protein 438 isoform a [Homo sapiens]
          Length = 828

 Score = 29.6 bits (65), Expect = 9.5
 Identities = 23/73 (31%), Positives = 30/73 (41%), Gaps = 8/73 (10%)

Query: 243 PHHPEMAKKLSQMDQVIQGLVERLENDTLLVVAGDHGMTTNGDHGGDSELEVSAALFLYS 302
           PHHPE+  K S  ++V       LE     +        TNG   GD    V+      +
Sbjct: 164 PHHPELLYKPSPFEEV-----PSLEQAPASISTA---ALTNGSDHGDLRPPVTNTHGSLN 215

Query: 303 PTAVFPSTPPEEP 315
           P A   S+ PEEP
Sbjct: 216 PPATPASSTPEEP 228


>gi|33300651 zinc finger protein 438 isoform a [Homo sapiens]
          Length = 828

 Score = 29.6 bits (65), Expect = 9.5
 Identities = 23/73 (31%), Positives = 30/73 (41%), Gaps = 8/73 (10%)

Query: 243 PHHPEMAKKLSQMDQVIQGLVERLENDTLLVVAGDHGMTTNGDHGGDSELEVSAALFLYS 302
           PHHPE+  K S  ++V       LE     +        TNG   GD    V+      +
Sbjct: 164 PHHPELLYKPSPFEEV-----PSLEQAPASISTA---ALTNGSDHGDLRPPVTNTHGSLN 215

Query: 303 PTAVFPSTPPEEP 315
           P A   S+ PEEP
Sbjct: 216 PPATPASSTPEEP 228


>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
          Length = 1979

 Score = 29.6 bits (65), Expect = 9.5
 Identities = 26/104 (25%), Positives = 39/104 (37%), Gaps = 13/104 (12%)

Query: 349  SGGEDSQPHSSALAQASALHLNAQQVSRFLHTYSAATQDLQ------AKELHQLQNLF-- 400
            +GG +S      L +   L    +++  +        Q++Q       +ELHQLQ     
Sbjct: 1196 AGGVNSNQFEELLQERDKLKQQVKKMEEWKQQVMTTVQNMQHESAQLQEELHQLQAQVLV 1255

Query: 401  -----SKASADYQWLLQSPKGAEATLPTVIAELQQFLRGARAMC 439
                 SK   DY  L+QS +  E  L     EL Q       +C
Sbjct: 1256 DSDNNSKLQVDYTGLIQSYEQNETKLKNFGQELAQVQHSIGQLC 1299


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.137    0.430 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,907,590
Number of Sequences: 37866
Number of extensions: 1328408
Number of successful extensions: 3921
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 3884
Number of HSP's gapped (non-prelim): 37
length of query: 672
length of database: 18,247,518
effective HSP length: 109
effective length of query: 563
effective length of database: 14,120,124
effective search space: 7949629812
effective search space used: 7949629812
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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