BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|37622887 carboxylesterase 2 isoform 2 [Homo sapiens] (607 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|37622887 carboxylesterase 2 isoform 2 [Homo sapiens] 1237 0.0 gi|37622885 carboxylesterase 2 isoform 1 [Homo sapiens] 1226 0.0 gi|33563374 carboxylesterase 3 [Homo sapiens] 469 e-132 gi|68508957 carboxylesterase 1 isoform c precursor [Homo sapiens] 459 e-129 gi|68508967 carboxylesterase 1 isoform a precursor [Homo sapiens] 456 e-128 gi|68508965 carboxylesterase 1 isoform b precursor [Homo sapiens] 456 e-128 gi|219521907 carboxylesterase 7 isoform 1 [Homo sapiens] 452 e-127 gi|21450749 carboxylesterase 7 isoform 2 [Homo sapiens] 418 e-117 gi|115529439 carboxylesterase 8 (putative) [Homo sapiens] 359 4e-99 gi|31317256 X-linked neuroligin 4 [Homo sapiens] 280 2e-75 gi|24308209 X-linked neuroligin 4 [Homo sapiens] 280 2e-75 gi|4557239 acetylcholinesterase isoform E4-E6 precursor [Homo sa... 279 6e-75 gi|7710112 acetylcholinesterase isoform E4-E5 precursor [Homo sa... 278 1e-74 gi|40538788 neuroligin 4, Y-linked [Homo sapiens] 274 2e-73 gi|51593088 neuroligin 3 [Homo sapiens] 271 1e-72 gi|30840978 neuroligin 2 [Homo sapiens] 269 5e-72 gi|7662470 neuroligin 1 [Homo sapiens] 266 3e-71 gi|4557351 butyrylcholinesterase precursor [Homo sapiens] 258 9e-69 gi|169215613 PREDICTED: similar to hCG40360 [Homo sapiens] 228 9e-60 gi|169216018 PREDICTED: similar to hCG40360 [Homo sapiens] 228 2e-59 gi|148536848 carboxyl ester lipase precursor [Homo sapiens] 204 2e-52 gi|55770862 thyroglobulin [Homo sapiens] 177 3e-44 gi|239752162 PREDICTED: similar to hCG40360 [Homo sapiens] 115 9e-26 gi|68299767 arylacetamide deacetylase [Homo sapiens] 41 0.003 gi|61966717 arylacetamide deacetylase-like 4 [Homo sapiens] 40 0.006 gi|206597554 arylacetamide deacetylase-like 2 [Homo sapiens] 40 0.008 gi|37577089 dipeptidyl peptidase 8 isoform 3 [Homo sapiens] 35 0.26 gi|18450280 dipeptidyl peptidase 8 isoform 1 [Homo sapiens] 35 0.26 gi|239755571 PREDICTED: hypothetical protein [Homo sapiens] 33 0.76 gi|239744417 PREDICTED: similar to hCG2023245 [Homo sapiens] 33 0.76 >gi|37622887 carboxylesterase 2 isoform 2 [Homo sapiens] Length = 607 Score = 1237 bits (3200), Expect = 0.0 Identities = 607/607 (100%), Positives = 607/607 (100%) Query: 1 MTAQSRSPTTPTFPGPSQRTPLTPCPVQTPRLGKALIHCWTDPGQPLGEQQRVRRQRTET 60 MTAQSRSPTTPTFPGPSQRTPLTPCPVQTPRLGKALIHCWTDPGQPLGEQQRVRRQRTET Sbjct: 1 MTAQSRSPTTPTFPGPSQRTPLTPCPVQTPRLGKALIHCWTDPGQPLGEQQRVRRQRTET 60 Query: 61 SEPTMRLHRLRARLSAVACGLLLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAGVQ 120 SEPTMRLHRLRARLSAVACGLLLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAGVQ Sbjct: 61 SEPTMRLHRLRARLSAVACGLLLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAGVQ 120 Query: 121 TFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPS 180 TFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPS Sbjct: 121 TFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPS 180 Query: 181 DSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQ 240 DSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQ Sbjct: 181 DSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQ 240 Query: 241 YRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSS 300 YRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSS Sbjct: 241 YRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSS 300 Query: 301 LVVSPISQGLFHGAIMESGVALLPGLIASSADVISTVVANLSACDQVDSEALVGCLRGKS 360 LVVSPISQGLFHGAIMESGVALLPGLIASSADVISTVVANLSACDQVDSEALVGCLRGKS Sbjct: 301 LVVSPISQGLFHGAIMESGVALLPGLIASSADVISTVVANLSACDQVDSEALVGCLRGKS 360 Query: 361 KEEILAINKPFKMIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRI 420 KEEILAINKPFKMIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRI Sbjct: 361 KEEILAINKPFKMIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRI 420 Query: 421 YDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMF 480 YDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMF Sbjct: 421 YDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMF 480 Query: 481 VIPALQVAHFQCSRAPVYFYEFQHQPSWLKNIRPPHMKADHVKFTEEEEQLSRKMMKYWA 540 VIPALQVAHFQCSRAPVYFYEFQHQPSWLKNIRPPHMKADHVKFTEEEEQLSRKMMKYWA Sbjct: 481 VIPALQVAHFQCSRAPVYFYEFQHQPSWLKNIRPPHMKADHVKFTEEEEQLSRKMMKYWA 540 Query: 541 NFARNGNPNGEGLPHWPLFDQEEQYLQLNLQPAVGRALKAHRLQFWKKALPQKIQELEEP 600 NFARNGNPNGEGLPHWPLFDQEEQYLQLNLQPAVGRALKAHRLQFWKKALPQKIQELEEP Sbjct: 541 NFARNGNPNGEGLPHWPLFDQEEQYLQLNLQPAVGRALKAHRLQFWKKALPQKIQELEEP 600 Query: 601 EERHTEL 607 EERHTEL Sbjct: 601 EERHTEL 607 >gi|37622885 carboxylesterase 2 isoform 1 [Homo sapiens] Length = 623 Score = 1226 bits (3172), Expect = 0.0 Identities = 606/623 (97%), Positives = 607/623 (97%), Gaps = 16/623 (2%) Query: 1 MTAQSRSPTTPTFPGPSQRTPLTPCPVQTPRLGKALIHCWTDPGQPLGEQQRVRRQRTET 60 MTAQSRSPTTPTFPGPSQRTPLTPCPVQTPRLGKALIHCWTDPGQPLGEQQRVRRQRTET Sbjct: 1 MTAQSRSPTTPTFPGPSQRTPLTPCPVQTPRLGKALIHCWTDPGQPLGEQQRVRRQRTET 60 Query: 61 SEPTMRLHRLRARLSAVACGLLLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAGVQ 120 SEPTMRLHRLRARLSAVACGLLLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAGVQ Sbjct: 61 SEPTMRLHRLRARLSAVACGLLLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAGVQ 120 Query: 121 TFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPS 180 TFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPS Sbjct: 121 TFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPS 180 Query: 181 DSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQ 240 DSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQ Sbjct: 181 DSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQ 240 Query: 241 YRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSS 300 YRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSS Sbjct: 241 YRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSS 300 Query: 301 LVVSPISQGLFHGAIMESGVALLPGLIASSADVISTVVANLSACDQVDSEALVGCLRGKS 360 LVVSPISQGLFHGAIMESGVALLPGLIASSADVISTVVANLSACDQVDSEALVGCLRGKS Sbjct: 301 LVVSPISQGLFHGAIMESGVALLPGLIASSADVISTVVANLSACDQVDSEALVGCLRGKS 360 Query: 361 KEEILAINKPFKMIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRI 420 KEEILAINKPFKMIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRI Sbjct: 361 KEEILAINKPFKMIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRI 420 Query: 421 YDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMF 480 YDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMF Sbjct: 421 YDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMF 480 Query: 481 VIPALQVAHFQCSRAPVYFYEFQHQPSWLKNIRPPHMKADH----------------VKF 524 VIPALQVAHFQCSRAPVYFYEFQHQPSWLKNIRPPHMKADH +KF Sbjct: 481 VIPALQVAHFQCSRAPVYFYEFQHQPSWLKNIRPPHMKADHGDELPFVFRSFFGGNYIKF 540 Query: 525 TEEEEQLSRKMMKYWANFARNGNPNGEGLPHWPLFDQEEQYLQLNLQPAVGRALKAHRLQ 584 TEEEEQLSRKMMKYWANFARNGNPNGEGLPHWPLFDQEEQYLQLNLQPAVGRALKAHRLQ Sbjct: 541 TEEEEQLSRKMMKYWANFARNGNPNGEGLPHWPLFDQEEQYLQLNLQPAVGRALKAHRLQ 600 Query: 585 FWKKALPQKIQELEEPEERHTEL 607 FWKKALPQKIQELEEPEERHTEL Sbjct: 601 FWKKALPQKIQELEEPEERHTEL 623 >gi|33563374 carboxylesterase 3 [Homo sapiens] Length = 571 Score = 469 bits (1208), Expect = e-132 Identities = 256/556 (46%), Positives = 338/556 (60%), Gaps = 31/556 (5%) Query: 74 LSAVACGLLLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLG 133 L V C LL G + A P T G+V G V VKG + V FLGIPFA+PPLG Sbjct: 12 LVGVVCLLLACPATATGPEVAQPEVDTTLGRVRGRQVGVKGTDRLVNVFLGIPFAQPPLG 71 Query: 134 PLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSD--SMSEDCLYLS 191 P RF+ P P + W GVRD +T P MCLQD+ ++ S S+F + S+SEDCL L+ Sbjct: 72 PDRFSAPHPAQPWEGVRDASTAPPMCLQDVESMNS---SRFVLNGKQQIFSVSEDCLVLN 128 Query: 192 IYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLGVLGFFST 251 +Y+PA GS PVMVW+HGGAL+ G A+ YDGS LAA +VVVV +QYRLGVLGFFST Sbjct: 129 VYSPAEVPAGSGRPVMVWVHGGALITGAATSYDGSALAAYGDVVVVTVQYRLGVLGFFST 188 Query: 252 GDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLF 311 GD+HA GN G+LD VAALRWVQ+NIA FGG+ + VT+FG SAGG+ +S LV+SP++ GLF Sbjct: 189 GDEHAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLF 248 Query: 312 HGAIMESGVALLPGLIASSADVISTVVANLSACDQVDSEALVGCLRGKSKEEILAINKPF 371 H AI +SGV PG+I S ++ +AN AC +V CL+ K EE L ++K Sbjct: 249 HRAITQSGVITTPGIIDSHPWPLAQKIANTLACSSSSPAEMVQCLQQKEGEE-LVLSKKL 307 Query: 372 K--MIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEMDR 429 K + P VDG P+ P+ELL F VP ++GVNN+EF WLIP+ + DT ++M R Sbjct: 308 KNTIYPLTVDGTVFPKSPKELLKEKPFHSVPFLMGVNNHEFSWLIPRGWGLLDTMEQMSR 367 Query: 430 EASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMFVIPALQVAH 489 E A +LT L +PP + +EY+G N D Q FQE M D +P + + Sbjct: 368 EDMLAISTPVLTSLDVPPEMMPTVIDEYLGSNSDAQAKCQAFQEFMGDVFINVPTVSFSR 427 Query: 490 F-QCSRAPVYFYEFQHQPSWLKNIRPPHMKADH----------------------VKFTE 526 + + S +PV+FYEFQH+PS I+P +KADH + TE Sbjct: 428 YLRDSGSPVFFYEFQHRPSSFAKIKPAWVKADHGAEGAFVFGGPFLMDESSRLAFPEATE 487 Query: 527 EEEQLSRKMMKYWANFARNGNPNGEGLPHWPLFDQEEQYLQLNLQPAVGRALKAHRLQFW 586 EE+QLS MM W +FAR G+PN + LP WP F+Q EQYL++N P G+ + +QFW Sbjct: 488 EEKQLSLTMMAQWTHFARTGDPNSKALPPWPQFNQAEQYLEINPVPRAGQKFREAWMQFW 547 Query: 587 KKALPQKIQELEEPEE 602 + LP KIQ+ + ++ Sbjct: 548 SETLPSKIQQWHQKQK 563 >gi|68508957 carboxylesterase 1 isoform c precursor [Homo sapiens] Length = 566 Score = 459 bits (1180), Expect = e-129 Identities = 252/552 (45%), Positives = 340/552 (61%), Gaps = 37/552 (6%) Query: 90 GQDSASPIRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGV 149 G S+ P+ T G+VLG V ++G V FLGIPFAKPPLGPLRF PP+P E WS V Sbjct: 18 GHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFV 77 Query: 150 RDGTTHPAMCLQDLTAVE--SEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNLPVM 207 ++ T++P MC QD A + SE + P +SEDCLYL+IYTPA + + LPVM Sbjct: 78 KNATSYPPMCTQDPKAGQLLSELFTNRKENIPL-KLSEDCLYLNIYTPADLTKKNRLPVM 136 Query: 208 VWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVA 267 VWIHGG L+ G AS YDG LAA ENVVVV IQYRLG+ GFFSTGD+H+ GNWG+LDQVA Sbjct: 137 VWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVA 196 Query: 268 ALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLI 327 ALRWVQ NIA FGGNP VTIFGESAGG SVS LV+SP+++ LFH AI ESGVA L ++ Sbjct: 197 ALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVA-LTSVL 255 Query: 328 ASSADV--ISTVVANLSACDQVDSEALVGCLRGKSKEEILAINKPFK------------- 372 DV ++ +A + C S +V CLR K++EE+L K Sbjct: 256 VKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRES 315 Query: 373 --MIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEMDRE 430 ++ V+DG+ L + P+EL A +F VP +VG+N EFGWLIP +M ++ ++D++ Sbjct: 316 QPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMLMSYPLSEGQLDQK 375 Query: 431 ASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMFVIPALQVA-H 489 + + L K L+ + E+Y+G D + F +++AD MF +P++ VA + Sbjct: 376 TAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVARN 435 Query: 490 FQCSRAPVYFYEFQHQPSWLKNIRPPHMKADH--------------VKFTEEEEQLSRKM 535 + + AP Y YEFQ++PS+ +++P + DH +EEE +LS+ + Sbjct: 436 HRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGASEEEIRLSKMV 495 Query: 536 MKYWANFARNGNPNGEGLPHWPLFDQEEQYLQLNLQPAVGRALKAHRLQFWKKALPQKIQ 595 MK+WANFARNGNPNGEGLPHWP ++Q+E YLQ+ + LK + FW +K Sbjct: 496 MKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKDKEVAFWTNLFAKKAV 555 Query: 596 ELEEPEERHTEL 607 E + P+ H EL Sbjct: 556 E-KPPQTEHIEL 566 >gi|68508967 carboxylesterase 1 isoform a precursor [Homo sapiens] Length = 568 Score = 456 bits (1174), Expect = e-128 Identities = 252/553 (45%), Positives = 340/553 (61%), Gaps = 38/553 (6%) Query: 90 GQDSASPIRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGV 149 G S+ P+ T G+VLG V ++G V FLGIPFAKPPLGPLRF PP+P E WS V Sbjct: 19 GHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFV 78 Query: 150 RDGTTHPAMCLQDLTAVE--SEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNLPVM 207 ++ T++P MC QD A + SE + P +SEDCLYL+IYTPA + + LPVM Sbjct: 79 KNATSYPPMCTQDPKAGQLLSELFTNRKENIPL-KLSEDCLYLNIYTPADLTKKNRLPVM 137 Query: 208 VWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVA 267 VWIHGG L+ G AS YDG LAA ENVVVV IQYRLG+ GFFSTGD+H+ GNWG+LDQVA Sbjct: 138 VWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVA 197 Query: 268 ALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLI 327 ALRWVQ NIA FGGNP VTIFGESAGG SVS LV+SP+++ LFH AI ESGVA L ++ Sbjct: 198 ALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVA-LTSVL 256 Query: 328 ASSADV--ISTVVANLSACDQVDSEALVGCLRGKSKEEILAINKPFK------------- 372 DV ++ +A + C S +V CLR K++EE+L K Sbjct: 257 VKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRES 316 Query: 373 --MIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYD-TQKEMDR 429 ++ V+DG+ L + P+EL A +F VP +VG+N EFGWLIP + Y ++ ++D+ Sbjct: 317 QPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQ 376 Query: 430 EASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMFVIPALQVA- 488 + + + L K L+ + E+Y+G D + F +++AD MF +P++ VA Sbjct: 377 KTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVAR 436 Query: 489 HFQCSRAPVYFYEFQHQPSWLKNIRPPHMKADH--------------VKFTEEEEQLSRK 534 + + + AP Y YEFQ++PS+ +++P + DH +EEE +LS+ Sbjct: 437 NHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGASEEEIRLSKM 496 Query: 535 MMKYWANFARNGNPNGEGLPHWPLFDQEEQYLQLNLQPAVGRALKAHRLQFWKKALPQKI 594 +MK+WANFARNGNPNGEGLPHWP ++Q+E YLQ+ + LK + FW +K Sbjct: 497 VMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKDKEVAFWTNLFAKKA 556 Query: 595 QELEEPEERHTEL 607 E + P+ H EL Sbjct: 557 VE-KPPQTEHIEL 568 >gi|68508965 carboxylesterase 1 isoform b precursor [Homo sapiens] Length = 567 Score = 456 bits (1174), Expect = e-128 Identities = 252/553 (45%), Positives = 340/553 (61%), Gaps = 38/553 (6%) Query: 90 GQDSASPIRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGV 149 G S+ P+ T G+VLG V ++G V FLGIPFAKPPLGPLRF PP+P E WS V Sbjct: 18 GHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFV 77 Query: 150 RDGTTHPAMCLQDLTAVE--SEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNLPVM 207 ++ T++P MC QD A + SE + P +SEDCLYL+IYTPA + + LPVM Sbjct: 78 KNATSYPPMCTQDPKAGQLLSELFTNRKENIPL-KLSEDCLYLNIYTPADLTKKNRLPVM 136 Query: 208 VWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVA 267 VWIHGG L+ G AS YDG LAA ENVVVV IQYRLG+ GFFSTGD+H+ GNWG+LDQVA Sbjct: 137 VWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVA 196 Query: 268 ALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLI 327 ALRWVQ NIA FGGNP VTIFGESAGG SVS LV+SP+++ LFH AI ESGVA L ++ Sbjct: 197 ALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVA-LTSVL 255 Query: 328 ASSADV--ISTVVANLSACDQVDSEALVGCLRGKSKEEILAINKPFK------------- 372 DV ++ +A + C S +V CLR K++EE+L K Sbjct: 256 VKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRES 315 Query: 373 --MIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYD-TQKEMDR 429 ++ V+DG+ L + P+EL A +F VP +VG+N EFGWLIP + Y ++ ++D+ Sbjct: 316 QPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQ 375 Query: 430 EASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMFVIPALQVA- 488 + + + L K L+ + E+Y+G D + F +++AD MF +P++ VA Sbjct: 376 KTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVAR 435 Query: 489 HFQCSRAPVYFYEFQHQPSWLKNIRPPHMKADH--------------VKFTEEEEQLSRK 534 + + + AP Y YEFQ++PS+ +++P + DH +EEE +LS+ Sbjct: 436 NHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGASEEEIRLSKM 495 Query: 535 MMKYWANFARNGNPNGEGLPHWPLFDQEEQYLQLNLQPAVGRALKAHRLQFWKKALPQKI 594 +MK+WANFARNGNPNGEGLPHWP ++Q+E YLQ+ + LK + FW +K Sbjct: 496 VMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKDKEVAFWTNLFAKKA 555 Query: 595 QELEEPEERHTEL 607 E + P+ H EL Sbjct: 556 VE-KPPQTEHIEL 567 >gi|219521907 carboxylesterase 7 isoform 1 [Homo sapiens] Length = 575 Score = 452 bits (1164), Expect = e-127 Identities = 242/532 (45%), Positives = 331/532 (62%), Gaps = 40/532 (7%) Query: 89 QGQDSASPIRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSG 148 +G + P R T G + G V V G+ V FLG+PFA PPLG LRF P+P W Sbjct: 24 KGPSAEGPQRNTRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPASPWDN 83 Query: 149 VRDGTTHPAMCLQDLTAVESEFL----SQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNL 204 +R+ T++P +CLQ+ SE+L + +P +SEDCLYL+IY PAH+ GS L Sbjct: 84 LREATSYPNLCLQN-----SEWLLLDQHMLKVHYPKFGVSEDCLYLNIYAPAHADTGSKL 138 Query: 205 PVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLD 264 PV+VW GGA G AS++DGS LAA E+V+VV++QYRLG+ GFF+T D+HA GNW + D Sbjct: 139 PVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKD 198 Query: 265 QVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVALLP 324 QVAAL WVQ+NI FGG+P VTIFGESAG SVSSL++SP+++GLFH AIMESGVA++P Sbjct: 199 QVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAIIP 258 Query: 325 GLIA----SSADVISTVVANLSACDQVDSEALVGCLRGKSKEEILAINKPFKMIPGVVDG 380 L A S D+ VVA+ + DSEAL+ CLR K +E+L +++ K VVDG Sbjct: 259 YLEAHDYEKSEDL--QVVAHFCGNNASDSEALLRCLRTKPSKELLTLSQKTKSFTRVVDG 316 Query: 381 VFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEMDREASQAALQKML 440 F P P +LL+ F+ +PSI+GVNN+E G+L+P + + + + AL + Sbjct: 317 AFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLP----MKEAPEILSGSNKSLALHLIQ 372 Query: 441 TLLMLPPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMFVIPALQVAHF-QCSRAPVYF 499 +L +PP + L+ EY D ++ +++ D FV+PAL A + + + APVYF Sbjct: 373 NILHIPPQYLHLVANEYFHDKHSLTEIRDSLLDLLGDVFFVVPALITARYHRDAGAPVYF 432 Query: 500 YEFQHQPSWLKNIRPPHMKADH---VKF-----------------TEEEEQLSRKMMKYW 539 YEF+H+P ++ +P +KADH V+F TEEE+ LSRKMMKYW Sbjct: 433 YEFRHRPQCFEDTKPAFVKADHADEVRFVFGGAFLKGDIVMFEGATEEEKLLSRKMMKYW 492 Query: 540 ANFARNGNPNGEGLPHWPLFDQEEQYLQLNLQPAVGRALKAHRLQFWKKALP 591 A FAR GNPNG L WP ++ EQYLQL+L ++G+ LK R+ FW +P Sbjct: 493 ATFARTGNPNGNDLSLWPAYNLTEQYLQLDLNMSLGQRLKEPRVDFWTSTIP 544 >gi|21450749 carboxylesterase 7 isoform 2 [Homo sapiens] Length = 525 Score = 418 bits (1075), Expect = e-117 Identities = 226/511 (44%), Positives = 306/511 (59%), Gaps = 48/511 (9%) Query: 89 QGQDSASPIRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSG 148 +G + P R T G + G V V G+ V FLG+PFA PPLG LRF P+P W Sbjct: 24 KGPSAEGPQRNTRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPASPWDN 83 Query: 149 VRDGTTHPAMCLQDLTAVESEFL----SQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNL 204 +R+ T++P +CLQ+ SE+L + +P +SEDCLYL+IY PAH+ GS L Sbjct: 84 LREATSYPNLCLQN-----SEWLLLDQHMLKVHYPKFGVSEDCLYLNIYAPAHADTGSKL 138 Query: 205 PVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLD 264 PV+VW GGA G AS++DGS LAA E+V+VV++QYRLG+ GFF+T D+HA GNW + D Sbjct: 139 PVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKD 198 Query: 265 QVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVALLP 324 QVAAL WVQ+NI FGG+P VTIFGESAG SVSSL++SP+++GLFH AIMESGVA++P Sbjct: 199 QVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAIIP 258 Query: 325 GLIA----SSADVISTVVANLSACDQVDSEALVGCLRGKSKEEILAINKPFKMIPGVVDG 380 L A S D+ VVA+ + DSEAL+ CLR K +E+L +++ K VVDG Sbjct: 259 YLEAHDYEKSEDL--QVVAHFCGNNASDSEALLRCLRTKPSKELLTLSQKTKSFTRVVDG 316 Query: 381 VFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEMDREASQAALQKML 440 F P P +LL+ F+ +PSI+GVNN+E G+L+P + + + + AL + Sbjct: 317 AFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLP----MKEAPEILSGSNKSLALHLIQ 372 Query: 441 TLLMLPPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMFVIPALQVAHFQCSRAPVYFY 500 +L +PP + L+ EY D ++ +++ D FV+PAL A + A Sbjct: 373 NILHIPPQYLHLVANEYFHDKHSLTEIRDSLLDLLGDVFFVVPALITARYHREGA----- 427 Query: 501 EFQHQPSWLKNIRPPHMKADHVKFTEEEEQLSRKMMKYWANFARNGNPNGEGLPHWPLFD 560 TEEE+ LSRKMMKYWA FAR GNPNG L WP ++ Sbjct: 428 ------------------------TEEEKLLSRKMMKYWATFARTGNPNGNDLSLWPAYN 463 Query: 561 QEEQYLQLNLQPAVGRALKAHRLQFWKKALP 591 EQYLQL+L ++G+ LK R+ FW +P Sbjct: 464 LTEQYLQLDLNMSLGQRLKEPRVDFWTSTIP 494 >gi|115529439 carboxylesterase 8 (putative) [Homo sapiens] Length = 491 Score = 359 bits (922), Expect = 4e-99 Identities = 205/525 (39%), Positives = 285/525 (54%), Gaps = 80/525 (15%) Query: 96 PIRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTH 155 P T G + G +HV +Q FLG+PF++PPLG LRFAPPEPPE W G+RD TT+ Sbjct: 27 PQVVTKYGTLQGKQMHV--GKTPIQVFLGVPFSRPPLGILRFAPPEPPEPWKGIRDATTY 84 Query: 156 PAMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGAL 215 P CLQ+ + + SEDCLYL++Y PA + LPVMVW GGA Sbjct: 85 PPGCLQESWGQLASMYVSTRERYKWLRFSEDCLYLNVYAPARAPGDPQLPVMVWFPGGAF 144 Query: 216 VFGMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQN 275 + G AS Y+GS LAA E VV+V +Q+RLG+ GF ST D HA GNWG LDQ+AALRWVQ+N Sbjct: 145 IVGAASSYEGSDLAAREKVVLVFLQHRLGIFGFLSTDDSHARGNWGLLDQMAALRWVQEN 204 Query: 276 IAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLIASSADVIS 335 IA FGG+P VT+FG+SAG S+S L++SP++ GLFH AI +SG AL I S+ ++ Sbjct: 205 IAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLFHRAISQSGTALFRLFITSNPLKVA 264 Query: 336 TVVANLSACDQVDSEALVGCLRGKSKEEILAINKPFKMI---------------PGVVDG 380 VA+L+ C+ ++ LV CLR S +++ ++ + + VVDG Sbjct: 265 KKVAHLAGCNHNSTQILVNCLRALSGTKVMRVSNKMRFLQLNFQRDPEEIIWSMSPVVDG 324 Query: 381 VFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEMDREASQAALQKML 440 V +P P LL VP ++GVNN EF WL+P Y+ KE Sbjct: 325 VVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWLLP-----YNITKE-------------- 365 Query: 441 TLLMLPPTFGDLLREEYIG--DNGDPQTLQAQFQEMMADSMFVIPALQVAHFQCSRAPVY 498 +P L+ EEY+ + D + L+ + +++ D+ FV LQ AH+ + Sbjct: 366 ---QVP-----LVVEEYLDNVNEHDWKMLRNRMMDIVQDATFVYATLQTAHYHRGLS--- 414 Query: 499 FYEFQHQPSWLKNIRPPHMKADHVKFTEEEEQLSRKMMKYWANFARNGNPNGEGLPHWPL 558 +E+ LS +MMKYWANFAR GNPN LP WP Sbjct: 415 --------------------------MGKEKALSLQMMKYWANFARTGNPNDGNLPCWPR 448 Query: 559 FDQEEQYLQLNLQPAVGRALKAHRLQFWKKALPQKIQELEEPEER 603 ++++E+YLQL+ VG LK ++ FW + + + PE++ Sbjct: 449 YNKDEKYLQLDFTTRVGMKLKEKKMAFW-----MSLYQSQRPEKQ 488 >gi|31317256 X-linked neuroligin 4 [Homo sapiens] Length = 816 Score = 280 bits (717), Expect = 2e-75 Identities = 185/573 (32%), Positives = 286/573 (49%), Gaps = 67/573 (11%) Query: 78 ACGLLLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAG-VQTFLGIPFAKPPLGPLR 136 A + L+ Q Q P+ T+ G++ G + G V+ +LG+P+A PP G R Sbjct: 31 ALAIKFTLIDSQAQ---YPVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASPPTGERR 87 Query: 137 FAPPEPPESWSGVRDGTTHPAMC---------LQDLTAVESEFLSQFNMTFPSDSMSEDC 187 F PPEPP SW+G+R+ T A+C L D+ + MT+ D +EDC Sbjct: 88 FQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQ-NEDC 146 Query: 188 LYLSIYTPAHSH---EGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLG 244 LYL+IY P + S PVMV+IHGG+ + G ++ DGS+LA+ NV+V+ I YRLG Sbjct: 147 LYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLG 206 Query: 245 VLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVS 304 +LGF STGD+ A GN+G LDQ+ ALRW+++N+ FGG+P RVTIFG AG + VS L +S Sbjct: 207 ILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLS 266 Query: 305 PISQGLFHGAIMESGVALLPGLIASSADVISTVVANLSACDQVDSEALVGCLRGKSKEEI 364 S+GLF AI++SG AL + + ++A+ C+ +D+ +V CLR K+ +E+ Sbjct: 267 HYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNYKEL 326 Query: 365 L---AINKPFKMIPG-VVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRI 420 + + + G V+DG +P PQ L+ +F ++GVN E + V I Sbjct: 327 IQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEG---LKFVDGI 383 Query: 421 YDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEY------IGDNGDPQTLQAQFQEM 474 D + + ++ + L P D LRE D +P+T + + Sbjct: 384 VDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVAL 443 Query: 475 MADSMFVIPALQVAHFQCS-RAPVYFYEFQH------QPSWLKNIRPPHM---------- 517 D +V PA+ A +P YFY F H +PSW + + Sbjct: 444 FTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIG 503 Query: 518 --KADHVKFTEEEEQLSRKMMKYWANFARNGNPNGEGLPH----------------WPLF 559 + F++ + LS +M YW NFA+ G+PN + +P W + Sbjct: 504 PTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPN-QPVPQDTKFIHTKPNRFEEVAWSKY 562 Query: 560 DQEEQ-YLQLNLQPAVGRALKAHRLQFWKKALP 591 + ++Q YL + L+P V +A ++ FW + +P Sbjct: 563 NPKDQLYLHIGLKPRVRDHYRATKVAFWLELVP 595 >gi|24308209 X-linked neuroligin 4 [Homo sapiens] Length = 816 Score = 280 bits (717), Expect = 2e-75 Identities = 185/573 (32%), Positives = 286/573 (49%), Gaps = 67/573 (11%) Query: 78 ACGLLLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAG-VQTFLGIPFAKPPLGPLR 136 A + L+ Q Q P+ T+ G++ G + G V+ +LG+P+A PP G R Sbjct: 31 ALAIKFTLIDSQAQ---YPVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASPPTGERR 87 Query: 137 FAPPEPPESWSGVRDGTTHPAMC---------LQDLTAVESEFLSQFNMTFPSDSMSEDC 187 F PPEPP SW+G+R+ T A+C L D+ + MT+ D +EDC Sbjct: 88 FQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQ-NEDC 146 Query: 188 LYLSIYTPAHSH---EGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLG 244 LYL+IY P + S PVMV+IHGG+ + G ++ DGS+LA+ NV+V+ I YRLG Sbjct: 147 LYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLG 206 Query: 245 VLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVS 304 +LGF STGD+ A GN+G LDQ+ ALRW+++N+ FGG+P RVTIFG AG + VS L +S Sbjct: 207 ILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLS 266 Query: 305 PISQGLFHGAIMESGVALLPGLIASSADVISTVVANLSACDQVDSEALVGCLRGKSKEEI 364 S+GLF AI++SG AL + + ++A+ C+ +D+ +V CLR K+ +E+ Sbjct: 267 HYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNYKEL 326 Query: 365 L---AINKPFKMIPG-VVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRI 420 + + + G V+DG +P PQ L+ +F ++GVN E + V I Sbjct: 327 IQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEG---LKFVDGI 383 Query: 421 YDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEY------IGDNGDPQTLQAQFQEM 474 D + + ++ + L P D LRE D +P+T + + Sbjct: 384 VDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVAL 443 Query: 475 MADSMFVIPALQVAHFQCS-RAPVYFYEFQH------QPSWLKNIRPPHM---------- 517 D +V PA+ A +P YFY F H +PSW + + Sbjct: 444 FTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIG 503 Query: 518 --KADHVKFTEEEEQLSRKMMKYWANFARNGNPNGEGLPH----------------WPLF 559 + F++ + LS +M YW NFA+ G+PN + +P W + Sbjct: 504 PTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPN-QPVPQDTKFIHTKPNRFEEVAWSKY 562 Query: 560 DQEEQ-YLQLNLQPAVGRALKAHRLQFWKKALP 591 + ++Q YL + L+P V +A ++ FW + +P Sbjct: 563 NPKDQLYLHIGLKPRVRDHYRATKVAFWLELVP 595 >gi|4557239 acetylcholinesterase isoform E4-E6 precursor [Homo sapiens] Length = 614 Score = 279 bits (713), Expect = 6e-75 Identities = 196/579 (33%), Positives = 296/579 (51%), Gaps = 63/579 (10%) Query: 76 AVACGLLLLL-------VRGQGQDSASPIRTTHTGQVLGSLVHVKGANAGVQTFLGIPFA 128 ++A LLLLL V +G++ A + T G++ G + +K V FLGIPFA Sbjct: 12 SLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRG--IRLKTPGGPVSAFLGIPFA 69 Query: 129 KPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSDSMSEDCL 188 +PP+GP RF PPEP + WSGV D TT ++C Q + + F M P+ +SEDCL Sbjct: 70 EPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGT-EMWNPNRELSEDCL 128 Query: 189 YLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASL--YDGSMLAALENVVVVIIQYRLGVL 246 YL+++TP + S PV+VWI+GG G +SL YDG L E V+V + YR+G Sbjct: 129 YLNVWTP-YPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAF 187 Query: 247 GFFST-GDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSP 305 GF + G + A GN G LDQ AL+WVQ+N+A FGG+P VT+FGESAG SV ++SP Sbjct: 188 GFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSP 247 Query: 306 ISQGLFHGAIMESGVALLPGLIASSADV--ISTVVANLSACDQ----VDSEALVGCLRGK 359 S+GLFH A+++SG P + +T +A+L C + LV CLR + Sbjct: 248 PSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTELVACLRTR 307 Query: 360 SKEEILAINKPFKMIP----------GVVDGVFLPRHPQELLASADFQPVPSIVGVNNNE 409 + + +N + ++P VVDG FL P+ L+ + DF + +VGV +E Sbjct: 308 PAQ--VLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDE 365 Query: 410 FGWLIPKVMRIYDTQK-EMDREASQAALQKMLTLLMLPPTFGDLLREEYI------GDNG 462 + + +Y D E+ + + + + + P DL E + Sbjct: 366 GSYFL-----VYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPE 420 Query: 463 DPQTLQAQFQEMMADSMFVIPALQVA-HFQCSRAPVYFYEFQHQP---SWLKNIRPPH-M 517 DP L+ +++ D V P Q+A A VY Y F+H+ SW + PH Sbjct: 421 DPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGY 480 Query: 518 KADHV---------KFTEEEEQLSRKMMKYWANFARNGNPN---GEGLPHWPLFDQ-EEQ 564 + + + +T EE+ ++++M+YWANFAR G+PN P WP + +Q Sbjct: 481 EIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQ 540 Query: 565 YLQLNLQP-AVGRALKAHRLQFWKKALPQKIQELEEPEE 602 Y+ L+L+P V R L+A FW + LP+ + + +E Sbjct: 541 YVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDE 579 >gi|7710112 acetylcholinesterase isoform E4-E5 precursor [Homo sapiens] Length = 617 Score = 278 bits (710), Expect = 1e-74 Identities = 195/569 (34%), Positives = 292/569 (51%), Gaps = 63/569 (11%) Query: 76 AVACGLLLLL-------VRGQGQDSASPIRTTHTGQVLGSLVHVKGANAGVQTFLGIPFA 128 ++A LLLLL V +G++ A + T G++ G + +K V FLGIPFA Sbjct: 12 SLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRG--IRLKTPGGPVSAFLGIPFA 69 Query: 129 KPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSDSMSEDCL 188 +PP+GP RF PPEP + WSGV D TT ++C Q + + F M P+ +SEDCL Sbjct: 70 EPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGT-EMWNPNRELSEDCL 128 Query: 189 YLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASL--YDGSMLAALENVVVVIIQYRLGVL 246 YL+++TP + S PV+VWI+GG G +SL YDG L E V+V + YR+G Sbjct: 129 YLNVWTP-YPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAF 187 Query: 247 GFFST-GDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSP 305 GF + G + A GN G LDQ AL+WVQ+N+A FGG+P VT+FGESAG SV ++SP Sbjct: 188 GFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSP 247 Query: 306 ISQGLFHGAIMESGVALLPGLIASSADV--ISTVVANLSACDQ----VDSEALVGCLRGK 359 S+GLFH A+++SG P + +T +A+L C + LV CLR + Sbjct: 248 PSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTELVACLRTR 307 Query: 360 SKEEILAINKPFKMIP----------GVVDGVFLPRHPQELLASADFQPVPSIVGVNNNE 409 + + +N + ++P VVDG FL P+ L+ + DF + +VGV +E Sbjct: 308 PAQ--VLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDE 365 Query: 410 FGWLIPKVMRIYDTQK-EMDREASQAALQKMLTLLMLPPTFGDLLREEYI------GDNG 462 + + +Y D E+ + + + + + P DL E + Sbjct: 366 GSYFL-----VYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPE 420 Query: 463 DPQTLQAQFQEMMADSMFVIPALQVA-HFQCSRAPVYFYEFQHQP---SWLKNIRPPH-M 517 DP L+ +++ D V P Q+A A VY Y F+H+ SW + PH Sbjct: 421 DPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGY 480 Query: 518 KADHV---------KFTEEEEQLSRKMMKYWANFARNGNPN---GEGLPHWPLFDQ-EEQ 564 + + + +T EE+ ++++M+YWANFAR G+PN P WP + +Q Sbjct: 481 EIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQ 540 Query: 565 YLQLNLQP-AVGRALKAHRLQFWKKALPQ 592 Y+ L+L+P V R L+A FW + LP+ Sbjct: 541 YVSLDLRPLEVRRGLRAQACAFWNRFLPK 569 >gi|40538788 neuroligin 4, Y-linked [Homo sapiens] Length = 816 Score = 274 bits (700), Expect = 2e-73 Identities = 182/573 (31%), Positives = 284/573 (49%), Gaps = 67/573 (11%) Query: 78 ACGLLLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAG-VQTFLGIPFAKPPLGPLR 136 A + L+ Q Q P+ T+ G++ G + G V+ +LG+P+A PP G R Sbjct: 31 ALAIKFTLIDSQAQ---YPVVNTNYGKIQGLRTPLPSEILGPVEQYLGVPYASPPTGERR 87 Query: 137 FAPPEPPESWSGVRDGTTHPAMC---------LQDLTAVESEFLSQFNMTFPSDSMSEDC 187 F PPE P SW+G+R+ T A+C L D+ + MT+ D +EDC Sbjct: 88 FQPPESPSSWTGIRNATQFSAVCPQHLDERFLLHDMLPIWFTTSLDTLMTYVQDQ-NEDC 146 Query: 188 LYLSIYTPAHS---HEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLG 244 LYL+IY P + S PVMV+IHGG+ + G ++ DGS+LA+ NV+V+ I RLG Sbjct: 147 LYLNIYVPMEDDIHEQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINCRLG 206 Query: 245 VLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVS 304 +LGF STGD+ A GN+G LDQ+ ALRW+++N+ FGG+P RVTIFG AG + VS L +S Sbjct: 207 ILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLS 266 Query: 305 PISQGLFHGAIMESGVALLPGLIASSADVISTVVANLSACDQVDSEALVGCLRGKSKEEI 364 S+GLF AI++SG AL + + ++A+ C+ +D+ +V CL+ K+ +E+ Sbjct: 267 HYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLKNKNYKEL 326 Query: 365 L---AINKPFKMIPG-VVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRI 420 + + + G V+DG +P PQ L+ +F ++GVN E + V I Sbjct: 327 IQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEG---LKFVDGI 383 Query: 421 YDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEY------IGDNGDPQTLQAQFQEM 474 D + + ++ + L P D LRE D +P+T + + Sbjct: 384 VDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVAL 443 Query: 475 MADSMFVIPALQVAHFQCS-RAPVYFYEFQH------QPSWLKNIRPPHM---------- 517 D +V PA+ A +P YFY F H +PSW + + Sbjct: 444 FTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIG 503 Query: 518 --KADHVKFTEEEEQLSRKMMKYWANFARNGNPNGEGLPH----------------WPLF 559 + F++ + LS +M YW NFA+ G+PN + +P W + Sbjct: 504 PTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPN-QPVPQDTKFIHTKPNRFEEVAWSKY 562 Query: 560 DQEEQ-YLQLNLQPAVGRALKAHRLQFWKKALP 591 + ++Q YL + L+P V +A ++ FW + +P Sbjct: 563 NPKDQLYLHIGLKPRVRDHYRATKVAFWLELVP 595 >gi|51593088 neuroligin 3 [Homo sapiens] Length = 828 Score = 271 bits (693), Expect = 1e-72 Identities = 186/588 (31%), Positives = 286/588 (48%), Gaps = 85/588 (14%) Query: 82 LLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAG-VQTFLGIPFAKPPLGPLRFAPP 140 L L +R Q A P TH G++ G+ V + G V +LG+P+A PP+G RF PP Sbjct: 29 LSLALRASTQAPA-PTVNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPPIGEKRFLPP 87 Query: 141 EPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSDSMS-------EDCLYLSIY 193 EPP SWSG+R+ T P +C Q++ E + T D ++ EDCLYL++Y Sbjct: 88 EPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVY 147 Query: 194 TPAHSHEGSNL----------------------PVMVWIHGGALVFGMASLYDGSMLAAL 231 P G+ PVMV+IHGG+ + G ++ DGS+LA+ Sbjct: 148 VPTEDGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSILASY 207 Query: 232 ENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGE 291 NV+V+ + YR+GVLGF STGD+ A GN+G LDQ+ ALRWV +NIA FGG+P R+T+FG Sbjct: 208 GNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGS 267 Query: 292 SAGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLIASSADVISTVVANLSACDQVDSEA 351 G + VS L +S S+GLF AI++SG AL + ++++A+ C+ +D+ Sbjct: 268 GIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDTVD 327 Query: 352 LVGCLRGKSKEEILAIN-KPFK---MIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNN 407 +V CLR KS +E++ + +P + V+DG +P P+ L+ +F ++GVN Sbjct: 328 MVDCLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIPDDPEILMEQGEFLNYDIMLGVNQ 387 Query: 408 NEFGWLIPKVMRIYDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEY------IGDN 461 E + V + D + + ++ + L P D LRE D Sbjct: 388 GEG---LKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADR 444 Query: 462 GDPQTLQAQFQEMMADSMFVIPALQVAHFQCS-RAPVYFYEFQHQPSWLKNIRPPHMKAD 520 +P+T + + D +V P++ A +P YFY F H L ++P A Sbjct: 445 DNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFYHHCQSL--MKPAWSDAA 502 Query: 521 H--------------------VKFTEEEEQLSRKMMKYWANFARNGNPNGEGLPH----- 555 H F++ + LS +M YW NFA+ G+PN + +P Sbjct: 503 HGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPN-KPVPQDTKFI 561 Query: 556 -----------WPLFDQEEQ-YLQLNLQPAVGRALKAHRLQFWKKALP 591 W ++ +Q YL + L+P V +A ++ FWK +P Sbjct: 562 HTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHLVP 609 >gi|30840978 neuroligin 2 [Homo sapiens] Length = 835 Score = 269 bits (688), Expect = 5e-72 Identities = 190/573 (33%), Positives = 281/573 (49%), Gaps = 85/573 (14%) Query: 96 PIRTTHTGQVLGSLVHVKGANAG-VQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTT 154 P+ T G+V G + G V FLG+P+A PPLG RF PPE P SW GVR+ TT Sbjct: 42 PVVNTAYGRVRGVRRELNNEILGPVVQFLGVPYATPPLGARRFQPPEAPASWPGVRNATT 101 Query: 155 HPAMCLQDLTAVESEFLSQFNMTFPSDS-------MSEDCLYLSIYTPAHS--------- 198 P C Q+L + T ++ SEDCLYL++Y P Sbjct: 102 LPPACPQNLHGALPAIMLPVWFTDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLTKKRDE 161 Query: 199 ----------HEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLGVLGF 248 + PVM+++HGG+ + G +++DGS+LAA NV+V + YRLGVLGF Sbjct: 162 ATLNPPDTDIRDPGKKPVMLFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYRLGVLGF 221 Query: 249 FSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQ 308 STGD+ A GN+G LDQ+ ALRW+ +NIAHFGG+P+R+TIFG AG + V+ L++S S+ Sbjct: 222 LSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHHSE 281 Query: 309 GLFHGAIMESGVALLPGLIASSADVISTVVANLSACDQVDSEALVGCLRGKSKEEILAIN 368 GLF AI +SG A+ + + ++A CD+ DS V CLR K E++ + Sbjct: 282 GLFQKAIAQSGTAISSWSVNYQPLKYTRLLAAKVGCDREDSAEAVECLRRKPSRELVDQD 341 Query: 369 -KPFK---MIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQ 424 +P + VVDG +P P+ L+ +F ++GVN E + V +++ Sbjct: 342 VQPARYHIAFGPVVDGDVVPDDPEILMQQGEFLNYDMLIGVNQGEG---LKFVEDSAESE 398 Query: 425 KEMDREASQAALQKMLTLLMLPPTFGDLLREEY--------IGDNGD--PQTLQAQFQEM 474 + A + + L P D+LRE DNG+ +TL A F Sbjct: 399 DGVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRDNGEMRRKTLLALF--- 455 Query: 475 MADSMFVIPALQVAHFQCS-RAPVYFYEFQH------QPSWLKNIR---------PPHMK 518 D +V PA+ A ++PVYFY F H +P W P + Sbjct: 456 -TDHQWVAPAVATAKLHADYQSPVYFYTFYHHCQAEGRPEWADAAHGDELPYVFGVPMVG 514 Query: 519 ADHV---KFTEEEEQLSRKMMKYWANFARNGNPNGEGLPH----------------WPLF 559 A + F++ + LS +M YW NFA+ G+PN + +P W F Sbjct: 515 ATDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPN-QPVPQDTKFIHTKPNRFEEVVWSKF 573 Query: 560 D-QEEQYLQLNLQPAVGRALKAHRLQFWKKALP 591 + +E+QYL + L+P V +A+++ FW + +P Sbjct: 574 NSKEKQYLHIGLKPRVRDNYRANKVAFWLELVP 606 >gi|7662470 neuroligin 1 [Homo sapiens] Length = 823 Score = 266 bits (681), Expect = 3e-71 Identities = 194/597 (32%), Positives = 286/597 (47%), Gaps = 78/597 (13%) Query: 67 LHR-LRARLSAVACGLLLLL--VRGQGQDSASPIRTTHTGQVLGSLVHVKGANAG-VQTF 122 +HR L A L+ G LL V Q D P+ T+ G++ G + G V F Sbjct: 21 VHRGLGAPLTLCMLGCLLQAGHVLSQKLDDVDPLVATNFGKIRGIKKELNNEILGPVIQF 80 Query: 123 LGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQD-----LTAVESEFLSQFNMT 177 LG+P+A PP G RF PPEPP WS +R+ T +C Q+ L V N+ Sbjct: 81 LGVPYAAPPTGERRFQPPEPPSPWSDIRNATQFAPVCPQNIIDGRLPEVMLPVWFTNNLD 140 Query: 178 FPSD---SMSEDCLYLSIYTPAHSH---EGSNLPVMVWIHGGALVFGMASLYDGSMLAAL 231 S SEDCLYL+IY P G PVMV+IHGG+ + G +LYDGS+LA+ Sbjct: 141 VVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIHGGSYMEGTGNLYDGSVLASY 200 Query: 232 ENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGE 291 NV+V+ + YRLGVLGF STGD+ A GN+G LD + ALRW +NI FGG+P R+T+FG Sbjct: 201 GNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGS 260 Query: 292 SAGGTSVSSLVVSPISQ---------GLFHGAIMESGVALLPGLIASSADVISTVVANLS 342 AGG+ V+ L +S S+ GLF AI +SG AL ++ + ++A Sbjct: 261 GAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARMLATKV 320 Query: 343 ACDQVDSEALVGCLRGKSKEEILAIN-KPFK---MIPGVVDGVFLPRHPQELLASADFQP 398 C+ D+ LV CL+ K +E++ + +P + V+DG +P PQ L+ +F Sbjct: 321 GCNVSDTVELVECLQKKPYKELVDQDIQPARYHIAFGPVIDGDVIPDDPQILMEQGEFLN 380 Query: 399 VPSIVGVNNNEFGWLIPKVMRIYDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEY- 457 ++GVN E + V I D+ + A+ + L P D+LRE Sbjct: 381 YDIMLGVNQGEG---LKFVENIVDSDDGISASDFDFAVSNFVDNLYGYPEGKDVLRETIK 437 Query: 458 -----IGDNGDPQTLQAQFQEMMADSMFVIPALQVAHFQCS-RAPVYFYEFQHQ------ 505 D +P+T + + D +V PA+ A + +P YFY F H Sbjct: 438 FMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFGSPTYFYAFYHHCQTDQV 497 Query: 506 PSW--------------LKNIRPPHMKADHVKFTEEEEQLSRKMMKYWANFARNGNPNGE 551 P+W + I P + F++ + LS +M YW NFA+ G+PN + Sbjct: 498 PAWADAAHGDEVPYVLGIPMIGPTELFP--CNFSKNDVMLSAVVMTYWTNFAKTGDPN-Q 554 Query: 552 GLPH----------------WPLFDQEEQ-YLQLNLQPAVGRALKAHRLQFWKKALP 591 +P W + Q++Q YL + L+P V +A+++ W + +P Sbjct: 555 PVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRANKVNLWLELVP 611 >gi|4557351 butyrylcholinesterase precursor [Homo sapiens] Length = 602 Score = 258 bits (660), Expect = 9e-69 Identities = 190/566 (33%), Positives = 282/566 (49%), Gaps = 52/566 (9%) Query: 81 LLLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPP 140 LLL ++ G+ I T G+V G + V G V FLGIP+A+PPLG LRF P Sbjct: 17 LLLCMLIGKSHTEDDIIIATKNGKVRGMNLTVFGGT--VTAFLGIPYAQPPLGRLRFKKP 74 Query: 141 EPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHE 200 + WS + + T + C Q++ F M P+ +SEDCLYL+++ PA + Sbjct: 75 QSLTKWSDIWNATKYANSCCQNIDQSFPGFHGS-EMWNPNTDLSEDCLYLNVWIPAPKPK 133 Query: 201 GSNLPVMVWIHGGALVFGMASL--YDGSMLAALENVVVVIIQYRLGVLGFFST-GDKHAT 257 N V++WI+GG G +SL YDG LA +E V+VV + YR+G LGF + G+ A Sbjct: 134 --NATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAP 191 Query: 258 GNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIME 317 GN G DQ AL+WVQ+NIA FGGNP VT+FGESAG SVS ++SP S LF AI++ Sbjct: 192 GNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQ 251 Query: 318 SGVALLPGLIASSADVISTV--VANLSACDQVDSEALVGCLRGKSKEEILAINKPFKMIP 375 SG P + S + + +A L+ C + + ++ CLR K +EIL +N+ F + Sbjct: 252 SGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEIL-LNEAFVVPY 310 Query: 376 G---------VVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKE 426 G VDG FL P LL F+ +VGVN +E + V K+ Sbjct: 311 GTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFL--VYGAPGFSKD 368 Query: 427 MDREASQAALQKMLTLLMLPPTFGDLLREEYI------GDNGDPQTLQAQFQEMMADSMF 480 + ++ Q+ L + P + +E + D+ P+ + +++ D F Sbjct: 369 NNSIITRKEFQEGLKIFF--PGVSEFGKESILFHYTDWVDDQRPENYREALGDVVGDYNF 426 Query: 481 VIPALQ-VAHFQCSRAPVYFYEFQHQ------PSWLKNIRP---------PHMKADHVKF 524 + PAL+ F +FY F+H+ P W+ + P + D+ + Sbjct: 427 ICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDN--Y 484 Query: 525 TEEEEQLSRKMMKYWANFARNGNPN--GEGLPHWPLFDQEEQ-YLQLNLQPA-VGRALKA 580 T+ EE LSR ++K WANFA+ GNPN WP+F EQ YL LN + + L+A Sbjct: 485 TKAEEILSRSIVKRWANFAKYGNPNETQNNSTSWPVFKSTEQKYLTLNTESTRIMTKLRA 544 Query: 581 HRLQFWKKALPQKIQELEEPEERHTE 606 + +FW P+ ++ +E E Sbjct: 545 QQCRFWTSFFPKVLEMTGNIDEAEWE 570 >gi|169215613 PREDICTED: similar to hCG40360 [Homo sapiens] Length = 327 Score = 228 bits (582), Expect = 9e-60 Identities = 127/289 (43%), Positives = 177/289 (61%), Gaps = 10/289 (3%) Query: 212 GGALVFGMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRW 271 GGA G AS++DGS LAA E+++VVI+QYRLG+ GFF+T D+HA GNW + DQVAAL W Sbjct: 20 GGAFETGSASIFDGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSW 79 Query: 272 VQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLIA--- 328 VQ+NI FGG+P VTIFGES G SVSSL++SP+++GLFH A+MESGVA++ L A Sbjct: 80 VQKNIEFFGGDPSSVTIFGESVGAISVSSLILSPMAEGLFHKAVMESGVAIILYLKAHDY 139 Query: 329 -SSADVISTVVANLSACDQVDSEALVGCLRGKSKEEILAINKPFKMIPGVVDGVFLPRHP 387 S D+ VVA + DSEA + CLR KS +E+L +++ K VVDG F P P Sbjct: 140 EKSEDL--QVVAQFCGYNASDSEAPLRCLRTKSSKELLTLSQKTKAFTQVVDGAFFPNEP 197 Query: 388 QELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEMDREASQAALQKMLTLLMLPP 447 +LL+ F+ +PSI+GVNN E G+ +P + + + + AL +L + P Sbjct: 198 LDLLSQKAFKAIPSIIGVNNPECGFPLP----MKEAPEILSGSNKSLALCLTQNILHILP 253 Query: 448 TFGDLLREEYIGDNGDPQTLQAQFQEMMADSMFVIPALQVAHFQCSRAP 496 + L+ EY D ++ +++ D FVIP L A + + P Sbjct: 254 NYLHLVAGEYFHDKHSLTEIRDSLLDLLGDVFFVIPKLITAQYHRGQIP 302 >gi|169216018 PREDICTED: similar to hCG40360 [Homo sapiens] Length = 327 Score = 228 bits (580), Expect = 2e-59 Identities = 127/289 (43%), Positives = 177/289 (61%), Gaps = 10/289 (3%) Query: 212 GGALVFGMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRW 271 GGA G AS++DGS LAA E+++VVI+QYRLG+ GFF+T D+HA GNW + DQVAAL W Sbjct: 20 GGAFETGSASIFDGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSW 79 Query: 272 VQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLIA--- 328 VQ+NI FGG+P VTIFGES G SVSSL++SP+++GLFH A+MESGVA++ L A Sbjct: 80 VQKNIEFFGGDPSSVTIFGESVGAISVSSLMLSPMAEGLFHKAVMESGVAIILYLKAHDY 139 Query: 329 -SSADVISTVVANLSACDQVDSEALVGCLRGKSKEEILAINKPFKMIPGVVDGVFLPRHP 387 S D+ VVA + DSEA + CLR KS +E+L +++ K VVDG F P P Sbjct: 140 EKSEDL--QVVAQFCGYNASDSEAPLRCLRTKSSKELLTLSQKTKAFTQVVDGAFFPNEP 197 Query: 388 QELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEMDREASQAALQKMLTLLMLPP 447 +LL+ F+ +PSI+GVNN E G+ +P + + + + AL +L + P Sbjct: 198 LDLLSQKAFKAIPSIIGVNNPECGFPLP----MKEAPEILSGSNKSLALCLTQNILHILP 253 Query: 448 TFGDLLREEYIGDNGDPQTLQAQFQEMMADSMFVIPALQVAHFQCSRAP 496 + L+ EY D ++ +++ D FVIP L A + + P Sbjct: 254 NYLHLVAGEYFHDKHSLTEIRDSLLDLLGDVFFVIPKLITARYHRGQIP 302 >gi|148536848 carboxyl ester lipase precursor [Homo sapiens] Length = 756 Score = 204 bits (519), Expect = 2e-52 Identities = 160/516 (31%), Positives = 233/516 (45%), Gaps = 68/516 (13%) Query: 119 VQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTF 178 V F GIPFA P P+P W G CLQ +S + Sbjct: 50 VDIFKGIPFAAPTKA---LENPQPHPGWQGTLKAKNFKKRCLQATITQDSTY-------- 98 Query: 179 PSDSMSEDCLYLSIYTPAHSHEGS-NLPVMVWIHGGALVFGMAS--------LYDGSMLA 229 EDCLYL+I+ P + S +LPVM+WI+GGA + G LYDG +A Sbjct: 99 ----GDEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIA 154 Query: 230 ALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIF 289 NV+VV YR+G LGF STGD + GN+G DQ A+ WV++NIA FGG+P+ +T+F Sbjct: 155 TRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLF 214 Query: 290 GESAGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLIASSADVISTVVANLSACDQVDS 349 GESAGG SVS +SP ++GL AI +SGVAL P +I + + VA C D+ Sbjct: 215 GESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDA 274 Query: 350 EALVGCLRGKS--------KEEILAINKPFKMIPG---VVDGVFLPRHPQELLASADFQP 398 + CL+ K + + P G V+DG F+P P L A+A Sbjct: 275 ARMAQCLKVTDPRALTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLYANA--AD 332 Query: 399 VPSIVGVNNNEFGWLIPKVMRIYDTQKEMDREASQAALQKMLTL---LMLPPTFGDLLRE 455 + I G NN + M + + E L T+ L T D+ E Sbjct: 333 IDYIAGTNNMDGHIFASIDMPAINKGNKKVTEEDFYKLVSEFTITKGLRGAKTTFDVYTE 392 Query: 456 EYIGDNGDPQTLQAQFQEMMADSMFVIP---ALQVAHFQCSRAPVYFYEFQHQPSWLKNI 512 + D + + + D +F++P AL A Y Y F H PS + + Sbjct: 393 SWAQDPSQ-ENKKKTVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSH-PSRMP-V 449 Query: 513 RPPHMKADHVK---------------FTEEEEQLSRKMMKYWANFARNGNPN--GEGLP- 554 P + ADH + ++ +S+ M+ YW NFA+ G+PN +P Sbjct: 450 YPKWVGADHADDIQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPT 509 Query: 555 HW-PLFDQEEQYLQLNLQ---PAVGRALKAHRLQFW 586 HW P + YL++ + ++ R+L+ + L++W Sbjct: 510 HWEPYTTENSGYLEITKKMGSSSMKRSLRTNFLRYW 545 >gi|55770862 thyroglobulin [Homo sapiens] Length = 2768 Score = 177 bits (448), Expect = 3e-44 Identities = 151/490 (30%), Positives = 231/490 (47%), Gaps = 63/490 (12%) Query: 99 TTHTGQVLG--SLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHP 156 +TH G++LG + V + V FLG+P+A PPL RF PEP +W+G D + Sbjct: 2204 STH-GRLLGRSQAIQVGTSWKQVDQFLGVPYAAPPLAERRFQAPEPL-NWTGSWDASKPR 2261 Query: 157 AMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGA-- 214 A C Q T T S +SEDCLYL+++ P + N V+V+ H Sbjct: 2262 ASCWQPGTR-----------TSTSPGVSEDCLYLNVFIP--QNVAPNASVLVFFHNTMDR 2308 Query: 215 -LVFGMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQ 273 G ++ DGS LAA+ N++VV YR+GV GF S+G +GNWG LDQVAAL WVQ Sbjct: 2309 EESEGWPAI-DGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQ 2367 Query: 274 QNIAHFGGNPDRVTIFGESAGG--TSVSSLVVSPISQGLFHGAIMESGVALLPGLIAS-- 329 +I FGG+P RV++ + G S+ L + LF A++ G AL P + S Sbjct: 2368 THIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHE 2427 Query: 330 SADVISTVVANLSACDQVDSEALVGCLRGK-------SKEEILAINKPFKMIPGVVDGVF 382 A + +A +C S+ +V CLR K ++ ++LA++ PF V+DG F Sbjct: 2428 RAQQQAIALAKEVSCPMSSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFHYWGPVIDGHF 2487 Query: 383 LPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEMDREASQAALQKMLTL 442 L P L + + V ++G + ++ LI + + ++ R +S+ A + L Sbjct: 2488 LREPPARALKRSLWVEVDLLIGSSQDD--GLINRAKAVKQFEESRGRTSSKTAFYQALQ- 2544 Query: 443 LMLPPTFGDLLRE---------EYIGDNGDPQTLQAQFQEMMADSMFVIPALQVAHFQCS 493 L D E E+ D D + + D + P + +A Sbjct: 2545 NSLGGEDSDARVEAAATWYYSLEHSTD--DYASFSRALENATRDYFIICPIIDMASAWAK 2602 Query: 494 RA--PVYFYEFQHQP--------SWLKNIR----PPHMKADHVKFTEEEEQLSRKMMKYW 539 RA V+ Y H P L +++ P A +F+ EE+ LS K+M+Y+ Sbjct: 2603 RARGNVFMY---HAPENYGHGSLELLADVQFALGLPFYPAYEGQFSLEEKSLSLKIMQYF 2659 Query: 540 ANFARNGNPN 549 ++F R+GNPN Sbjct: 2660 SHFIRSGNPN 2669 >gi|239752162 PREDICTED: similar to hCG40360 [Homo sapiens] Length = 131 Score = 115 bits (289), Expect = 9e-26 Identities = 53/90 (58%), Positives = 68/90 (75%) Query: 206 VMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQ 265 V++W GGA G AS++DGS LAA E+++VVI+QYRLG+ GFF+T D+HA GNW + DQ Sbjct: 20 VLLWFPGGAFETGSASIFDGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQ 79 Query: 266 VAALRWVQQNIAHFGGNPDRVTIFGESAGG 295 VAAL WVQ+NI FGG+P VTIF + G Sbjct: 80 VAALSWVQKNIEFFGGDPSSVTIFDAVSHG 109 >gi|68299767 arylacetamide deacetylase [Homo sapiens] Length = 399 Score = 41.2 bits (95), Expect = 0.003 Identities = 34/120 (28%), Positives = 53/120 (44%), Gaps = 16/120 (13%) Query: 188 LYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALE----NVVVVIIQYRL 243 + + +Y P E + +IHGG G A+L +L+ + VVV YRL Sbjct: 89 ILVRVYVPKRKSEALRRGLF-YIHGGGWCVGSAALSGYDLLSRWTADRLDAVVVSTNYRL 147 Query: 244 GVLGFFSTGDKHATGNWGYLDQVAALRWVQQN--IAHFGGNPDRVTIFGESAGGTSVSSL 301 F + D ALRW + +A +G NP+R+ I G+SAGG +++ Sbjct: 148 APKYHFPIQ---------FEDVYNALRWFLRKKVLAKYGVNPERIGISGDSAGGNLAAAV 198 >gi|61966717 arylacetamide deacetylase-like 4 [Homo sapiens] Length = 407 Score = 40.0 bits (92), Expect = 0.006 Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 11/97 (11%) Query: 207 MVWIHGGALVFGMASLYDG--SMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLD 264 +++ HGGA VFG Y G + LA V+++I YR D H+ + D Sbjct: 115 IIFYHGGATVFGSLDCYHGLCNYLARETESVLLMIGYR-------KLPDHHSPAL--FQD 165 Query: 265 QVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSL 301 + A + + +G +P RV + GES GG +V+++ Sbjct: 166 CMNASIHFLKALETYGVDPSRVVVCGESVGGAAVAAI 202 >gi|206597554 arylacetamide deacetylase-like 2 [Homo sapiens] Length = 401 Score = 39.7 bits (91), Expect = 0.008 Identities = 47/210 (22%), Positives = 87/210 (41%), Gaps = 33/210 (15%) Query: 139 PPEPPESWS-----GVRDGTTHPAMCLQDLTAVE-SEFLSQFNMTFPSDSMSEDCLYLS- 191 P ESW + T AMC +++ + EF+S + +S++ + ++ Sbjct: 24 PDNIEESWKIMALDAIAKTCTFTAMCFENMRIMRYEEFISMIFRLDYTQPLSDEYITVTD 83 Query: 192 ---------IYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSML----AALENVVVVI 238 +Y P E V ++ HGG FG + L A + VVV Sbjct: 84 TTFVDIPVRLYLPKRKSETRRRAV-IYFHGGGFCFGSSKQRAFDFLNRWTANTLDAVVVG 142 Query: 239 IQYRLGVLGFFSTGDKHATGNWGYLDQVAALRW--VQQNIAHFGGNPDRVTIFGESAGGT 296 + YRL F + D +AA+++ +++ + +G +P R+ I G+S+GG Sbjct: 143 VDYRLAPQHHFPAQ---------FEDGLAAVKFFLLEKILTKYGVDPTRICIAGDSSGG- 192 Query: 297 SVSSLVVSPISQGLFHGAIMESGVALLPGL 326 ++++ V + ++ V L PGL Sbjct: 193 NLATAVTQQVQNDAEIKHKIKMQVLLYPGL 222 >gi|37577089 dipeptidyl peptidase 8 isoform 3 [Homo sapiens] Length = 898 Score = 34.7 bits (78), Expect = 0.26 Identities = 44/152 (28%), Positives = 64/152 (42%), Gaps = 11/152 (7%) Query: 178 FPSDSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDG------SMLAAL 231 F +S + LY +Y P G P +++I+GG V + + + G + LA+L Sbjct: 636 FSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASL 695 Query: 232 ENVVVVIIQYRLGVLGF-FSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFG 290 VVVVI G F K+ G DQV L+++ + DRV I G Sbjct: 696 GYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFI--DLDRVGIHG 753 Query: 291 ESAGGTSVSSLVVSPISQGLFHGAIMESGVAL 322 S GG SL+ +F AI + V L Sbjct: 754 WSYGG--YLSLMALMQRSDIFRVAIAGAPVTL 783 >gi|18450280 dipeptidyl peptidase 8 isoform 1 [Homo sapiens] Length = 882 Score = 34.7 bits (78), Expect = 0.26 Identities = 44/152 (28%), Positives = 64/152 (42%), Gaps = 11/152 (7%) Query: 178 FPSDSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDG------SMLAAL 231 F +S + LY +Y P G P +++I+GG V + + + G + LA+L Sbjct: 620 FSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASL 679 Query: 232 ENVVVVIIQYRLGVLGF-FSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFG 290 VVVVI G F K+ G DQV L+++ + DRV I G Sbjct: 680 GYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFI--DLDRVGIHG 737 Query: 291 ESAGGTSVSSLVVSPISQGLFHGAIMESGVAL 322 S GG SL+ +F AI + V L Sbjct: 738 WSYGG--YLSLMALMQRSDIFRVAIAGAPVTL 767 >gi|239755571 PREDICTED: hypothetical protein [Homo sapiens] Length = 261 Score = 33.1 bits (74), Expect = 0.76 Identities = 36/123 (29%), Positives = 45/123 (36%), Gaps = 18/123 (14%) Query: 6 RSPTTPTFPGPSQRT-PLTPCPVQTPRLGKALIHCWTDP-------GQPLGEQQRVRRQR 57 R PT P PS PL P P +P G+A P G+P G R RR+ Sbjct: 93 RGPTEPALRRPSSADRPLAPGPSSSPGAGRAP-GAMASPSGSSKATGKPRGRDGRPRREE 151 Query: 58 TETSEPTMRLHRLRARLSAVACGLLLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANA 117 + + RL L SA G+D+ P R Q G V A A Sbjct: 152 DDVTPEEKRLRLLLEEGSAQP---------DDGEDAPRPGRKETGTQTGGDGRGVSDAGA 202 Query: 118 GVQ 120 GV+ Sbjct: 203 GVR 205 >gi|239744417 PREDICTED: similar to hCG2023245 [Homo sapiens] Length = 364 Score = 33.1 bits (74), Expect = 0.76 Identities = 36/123 (29%), Positives = 45/123 (36%), Gaps = 18/123 (14%) Query: 6 RSPTTPTFPGPSQRT-PLTPCPVQTPRLGKALIHCWTDP-------GQPLGEQQRVRRQR 57 R PT P PS PL P P +P G+A P G+P G R RR+ Sbjct: 196 RGPTEPALRRPSSADRPLAPGPSSSPGAGRAP-GAMASPSGSSKATGKPRGRDGRPRREE 254 Query: 58 TETSEPTMRLHRLRARLSAVACGLLLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANA 117 + + RL L SA G+D+ P R Q G V A A Sbjct: 255 DDVTPEEKRLRLLLEEGSAQP---------DDGEDAPRPGRKETGTQTGGDGRGVSDAGA 305 Query: 118 GVQ 120 GV+ Sbjct: 306 GVR 308 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.135 0.414 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 25,987,302 Number of Sequences: 37866 Number of extensions: 1281150 Number of successful extensions: 4203 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 25 Number of HSP's successfully gapped in prelim test: 15 Number of HSP's that attempted gapping in prelim test: 4072 Number of HSP's gapped (non-prelim): 48 length of query: 607 length of database: 18,247,518 effective HSP length: 108 effective length of query: 499 effective length of database: 14,157,990 effective search space: 7064837010 effective search space used: 7064837010 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.