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Search of human proteins with 37577103
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|37577103 C-type lectin-like receptor-1 [Homo sapiens]
(280 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|37577103 C-type lectin-like receptor-1 [Homo sapiens] 586 e-168
gi|194018501 C-type lectin domain family 12, member B isoform 1 ... 148 5e-36
gi|194018499 C-type lectin domain family 12, member B isoform 2 ... 136 2e-32
gi|94557290 myeloid inhibitory C-type lectin-like receptor isofo... 135 3e-32
gi|153252029 C-type lectin domain family 1, member B isoform a [... 131 6e-31
gi|4505501 oxidized low density lipoprotein (lectin-like) recept... 113 2e-25
gi|153252048 C-type lectin domain family 1, member B isoform b [... 113 2e-25
gi|94557293 myeloid inhibitory C-type lectin-like receptor isofo... 106 2e-23
gi|37675373 dendritic cell-associated C-type lectin 1 isoform a ... 105 3e-23
gi|37675379 dendritic cell-associated C-type lectin 1 isoform e ... 84 1e-16
gi|13384604 dendritic cell-associated C-type lectin 1 isoform b ... 84 1e-16
gi|46409326 C-type lectin domain family 9, member A [Homo sapiens] 78 8e-15
gi|7705574 killer cell lectin-like receptor subfamily F, member ... 75 8e-14
gi|167614498 killer cell lectin-like receptor subfamily D, membe... 74 1e-13
gi|7669499 killer cell lectin-like receptor subfamily D, member ... 74 1e-13
gi|4504889 killer cell lectin-like receptor subfamily D, member ... 74 1e-13
gi|169234653 NKG2-D type II integral membrane protein [Homo sapi... 71 9e-13
gi|7705338 C-type lectin domain family 4, member A isoform 1 [Ho... 67 2e-11
gi|75709169 killer cell lectin-like receptor subfamily C, member... 65 7e-11
gi|47717094 killer cell lectin-like receptor subfamily C, member... 65 7e-11
gi|4504881 killer cell lectin-like receptor subfamily C, member ... 65 7e-11
gi|18426877 asialoglycoprotein receptor 2 isoform c [Homo sapiens] 64 1e-10
gi|18426875 asialoglycoprotein receptor 2 isoform b [Homo sapiens] 64 1e-10
gi|18426873 asialoglycoprotein receptor 2 isoform a [Homo sapiens] 64 1e-10
gi|4502253 asialoglycoprotein receptor 2 isoform a [Homo sapiens] 64 1e-10
gi|47717092 killer cell lectin-like receptor subfamily C, member... 64 1e-10
gi|7262384 killer cell lectin-like receptor subfamily C, member ... 64 1e-10
gi|37577119 C-type lectin domain family 4, member A isoform 2 [H... 61 1e-09
gi|37577117 C-type lectin domain family 4, member A isoform 4 [H... 61 1e-09
gi|148536836 C-type lectin domain family 4, member A isoform 3 [... 61 1e-09
>gi|37577103 C-type lectin-like receptor-1 [Homo sapiens]
Length = 280
Score = 586 bits (1510), Expect = e-168
Identities = 280/280 (100%), Positives = 280/280 (100%)
Query: 1 MQAKYSSTRDMLDDDGDTTMSLHSQGSATTRHPEPRRTEHRAPSSTWRPVALTLLTLCLV 60
MQAKYSSTRDMLDDDGDTTMSLHSQGSATTRHPEPRRTEHRAPSSTWRPVALTLLTLCLV
Sbjct: 1 MQAKYSSTRDMLDDDGDTTMSLHSQGSATTRHPEPRRTEHRAPSSTWRPVALTLLTLCLV 60
Query: 61 LLIGLAALGLLFFQYYQLSNTGQDTISQMEERLGNTSQELQSLQVQNIKLAGSLQHVAEK 120
LLIGLAALGLLFFQYYQLSNTGQDTISQMEERLGNTSQELQSLQVQNIKLAGSLQHVAEK
Sbjct: 61 LLIGLAALGLLFFQYYQLSNTGQDTISQMEERLGNTSQELQSLQVQNIKLAGSLQHVAEK 120
Query: 121 LCRELYNKAGAHRCSPCTEQWKWHGDNCYQFYKDSKSWEDCKYFCLSENSTMLKINKQED 180
LCRELYNKAGAHRCSPCTEQWKWHGDNCYQFYKDSKSWEDCKYFCLSENSTMLKINKQED
Sbjct: 121 LCRELYNKAGAHRCSPCTEQWKWHGDNCYQFYKDSKSWEDCKYFCLSENSTMLKINKQED 180
Query: 181 LEFAASQSYSEFFYSYWTGLLRPDSGKAWLWMDGTPFTSELFHIIIDVTSPRSRDCVAIL 240
LEFAASQSYSEFFYSYWTGLLRPDSGKAWLWMDGTPFTSELFHIIIDVTSPRSRDCVAIL
Sbjct: 181 LEFAASQSYSEFFYSYWTGLLRPDSGKAWLWMDGTPFTSELFHIIIDVTSPRSRDCVAIL 240
Query: 241 NGMIFSKDCKELKRCVCERRAGMVKPESLHVPPETLGEGD 280
NGMIFSKDCKELKRCVCERRAGMVKPESLHVPPETLGEGD
Sbjct: 241 NGMIFSKDCKELKRCVCERRAGMVKPESLHVPPETLGEGD 280
>gi|194018501 C-type lectin domain family 12, member B isoform 1
[Homo sapiens]
Length = 276
Score = 148 bits (374), Expect = 5e-36
Identities = 91/271 (33%), Positives = 139/271 (51%), Gaps = 20/271 (7%)
Query: 18 TTMSLHSQGSATTRHPEP----RRTEHRAPSSTWRPVALTLLTLCLVLLIGLAALGLLFF 73
T +L Q SA R+ R+ H APS WR AL L+TLCL+LLIGL LG++F
Sbjct: 6 TYATLTFQDSAGARNNRDGNNLRKRGHPAPSPIWRHAALGLVTLCLMLLIGLVTLGMMFL 65
Query: 74 QYYQLSNTGQDTISQME-----------ERLGNT---SQELQSLQVQNIKLAGSLQHVAE 119
Q N+ + +SQ++ ++LGN+ S E + L+ Q + + +A
Sbjct: 66 QISNDINSDSEKLSQLQKTIQQQQDNLSQQLGNSNNLSMEEEFLKSQISSVLKRQEQMAI 125
Query: 120 KLCRELYNKAGAHRCSPCTEQWKWHGDNCYQF-YKDSKSWEDCKYFCLSENSTMLKINKQ 178
KLC+EL HRC+PC + W+W+ ++CY F + K+W + + C+ +NST++KI+
Sbjct: 126 KLCQELIIHTSDHRCNPCPKMWQWYQNSCYYFTTNEEKTWANSRKDCIDKNSTLVKIDSL 185
Query: 179 EDLEFAASQSYSEFFYSYWTGLLRPDSGKAWLWMDGTPFTSELFHIIIDVTSPRSRDCVA 238
E+ +F SQ F + +W GL SG++W W DG+ + LF S+ C
Sbjct: 186 EEKDFLMSQPLLMFSF-FWLGLSWDSSGRSWFWEDGSVPSPSLFSTKELDQINGSKGCAY 244
Query: 239 ILNGMIFSKDCKELKRCVCERRAGMVKPESL 269
G I+ C +CE+ A VK E L
Sbjct: 245 FQKGNIYISRCSAEIFWICEKTAAPVKTEDL 275
>gi|194018499 C-type lectin domain family 12, member B isoform 2
[Homo sapiens]
Length = 232
Score = 136 bits (342), Expect = 2e-32
Identities = 78/224 (34%), Positives = 123/224 (54%), Gaps = 20/224 (8%)
Query: 18 TTMSLHSQGSATTRHPEP----RRTEHRAPSSTWRPVALTLLTLCLVLLIGLAALGLLFF 73
T +L Q SA R+ R+ H APS WR AL L+TLCL+LLIGL LG++F
Sbjct: 6 TYATLTFQDSAGARNNRDGNNLRKRGHPAPSPIWRHAALGLVTLCLMLLIGLVTLGMMFL 65
Query: 74 QYYQLSNTGQDTISQME-----------ERLGNT---SQELQSLQVQNIKLAGSLQHVAE 119
Q N+ + +SQ++ ++LGN+ S E + L+ Q + + +A
Sbjct: 66 QISNDINSDSEKLSQLQKTIQQQQDNLSQQLGNSNNLSMEEEFLKSQISSVLKRQEQMAI 125
Query: 120 KLCRELYNKAGAHRCSPCTEQWKWHGDNCYQF-YKDSKSWEDCKYFCLSENSTMLKINKQ 178
KLC+EL HRC+PC + W+W+ ++CY F + K+W + + C+ +NST++KI+
Sbjct: 126 KLCQELIIHTSDHRCNPCPKMWQWYQNSCYYFTTNEEKTWANSRKDCIDKNSTLVKIDSL 185
Query: 179 EDLEFAASQSYSEFFYSYWTGLLRPDSGKAWLWMDGTPFTSELF 222
E+ +F SQ F + +W GL SG++W W DG+ + L+
Sbjct: 186 EEKDFLMSQPLLMFSF-FWLGLSWDSSGRSWFWEDGSVPSPSLY 228
>gi|94557290 myeloid inhibitory C-type lectin-like receptor isoform
alpha [Homo sapiens]
Length = 265
Score = 135 bits (341), Expect = 3e-32
Identities = 81/228 (35%), Positives = 119/228 (52%), Gaps = 9/228 (3%)
Query: 42 APSSTWRPVALTLLTLCLVLLIGLAALGLLFFQYYQLSNTGQDTISQMEERLG-NTSQEL 100
APS WRP AL L LCL+LLIGL L +F ++ + + + E L N S +L
Sbjct: 34 APSHVWRPAALFLTLLCLLLLIGLGVLASMFHVTLKIEMKKMNKLQNISEELQRNISLQL 93
Query: 101 QS-LQVQNI--KLAGSLQHVAEKLCRELYNKAGAHRCSPCTEQWKWHGDNCYQFYKDSKS 157
S + + N L+ +LQ +A KLCRELY+K H+C PC +W WH D+CY D ++
Sbjct: 94 MSNMNISNKIRNLSTTLQTIATKLCRELYSKEQEHKCKPCPRRWIWHKDSCYFLSDDVQT 153
Query: 158 WEDCKYFCLSENSTMLKINKQEDLEFAASQSYSEFFYSYWTGLLRPDSGKAWLWMDGTPF 217
W++ K C ++N+++LKIN + LEF SQS S Y YW GL + + +D
Sbjct: 154 WQESKMACAAQNASLLKINNKNALEFIKSQSRS---YDYWLGLSPEEDSTRGMRVDNIIN 210
Query: 218 TSELFHIIIDVTSPRSRDCVAILNGMIFSKDCKELKRCVCERRAGMVK 265
+S +I + + C I + C KR +CE+ A V+
Sbjct: 211 SSA--WVIRNAPDLNNMYCGYINRLYVQYYHCTYKKRMICEKMANPVQ 256
>gi|153252029 C-type lectin domain family 1, member B isoform a
[Homo sapiens]
Length = 229
Score = 131 bits (330), Expect = 6e-31
Identities = 76/265 (28%), Positives = 130/265 (49%), Gaps = 43/265 (16%)
Query: 11 MLDDDGDTTMSLHSQGSATTRHPEPRRTEHRAPSSTWRPVALTLLTLCLVLLIGLAALGL 70
M D+DG T+++ ++ A + A SS WR +AL LL LC+ +++GL ALG+
Sbjct: 1 MQDEDGYITLNIKTRKPALI-------SVGSASSSWWRVMALILLILCVGMVVGLVALGI 53
Query: 71 LFFQYYQLSNTGQDTISQMEERLGNTSQELQSLQVQNIKLAGSLQHVAEKLCR------E 124
+ + LQ +N G+LQ +A++ C+ E
Sbjct: 54 W------------------------SVMQRNYLQGENENRTGTLQQLAKRFCQYVVKQSE 89
Query: 125 LYNKAGAHRCSPCTEQWKWHGDNCYQFYKDSKSWEDCKYFCLSENSTMLKINKQEDLEFA 184
L H+CSPC W+++GD+CY F++ + +WE+ K +C N+T+LKI+ + +E+
Sbjct: 90 LKGTFKGHKCSPCDTNWRYYGDSCYGFFRHNLTWEESKQYCTDMNATLLKIDNRNIVEYI 149
Query: 185 ASQSYSEFFYSYWTGLLRPDSGKAWLWMDGTPFTSELFHIIIDVTSPRSRDCVAILNGMI 244
++++ W GL R S + W W DG+ + +F + D + +C NG +
Sbjct: 150 KARTH----LIRWVGLSRQKSNEVWKWEDGSVISENMFEFLED--GKGNMNCAYFHNGKM 203
Query: 245 FSKDCKELKRCVCERRAGMVKPESL 269
C+ +CER+AGM K + L
Sbjct: 204 HPTFCENKHYLMCERKAGMTKVDQL 228
>gi|4505501 oxidized low density lipoprotein (lectin-like) receptor
1 [Homo sapiens]
Length = 273
Score = 113 bits (283), Expect = 2e-25
Identities = 69/241 (28%), Positives = 112/241 (46%), Gaps = 23/241 (9%)
Query: 44 SSTWRPVALTLLTLCLVLLIGLAALGLLFFQYYQLSNTGQDTISQMEERLGNTSQELQSL 103
S W A TL LCL L++ + LG+ Q L Q ++ +++L Q
Sbjct: 32 SPWWCLAAATLGVLCLGLVVTIMVLGMQLSQVSDLLTQEQANLTHQKKKLEGQISARQQA 91
Query: 104 QVQNIKLAGSLQHVAEKLCRELYNKAG-------------------AHRCSPCTEQWKWH 144
+ + + L+ + E L R+L K+ A+ +PC + W WH
Sbjct: 92 EEASQESENELKEMIETLARKLNEKSKEQMELHHQNLNLQETLKRVANCSAPCPQDWIWH 151
Query: 145 GDNCYQFYKDSKSWEDCKYFCLSENSTMLKINKQEDLEFAASQSYSEFFYSYWTGLLRPD 204
G+NCY F S +WE + CLS ++ +LKIN DL+F Q+ S + +W GL R +
Sbjct: 152 GENCYLFSSGSFNWEKSQEKCLSLDAKLLKINSTADLDF-IQQAISYSSFPFWMGLSRRN 210
Query: 205 SGKAWLWMDGTPFTSELFHI--IIDVTSPRSRDCVAILNGMIFSKDCKELKRCVCERRAG 262
WLW DG+P LF + + T P S C I G +++++C +C+++A
Sbjct: 211 PSYPWLWEDGSPLMPHLFRVRGAVSQTYP-SGTCAYIQRGAVYAENCILAAFSICQKKAN 269
Query: 263 M 263
+
Sbjct: 270 L 270
>gi|153252048 C-type lectin domain family 1, member B isoform b
[Homo sapiens]
Length = 196
Score = 113 bits (282), Expect = 2e-25
Identities = 54/173 (31%), Positives = 93/173 (53%), Gaps = 12/173 (6%)
Query: 103 LQVQNIKLAGSLQHVAEKLCR------ELYNKAGAHRCSPCTEQWKWHGDNCYQFYKDSK 156
LQ +N G+LQ +A++ C+ EL H+CSPC W+++GD+CY F++ +
Sbjct: 29 LQGENENRTGTLQQLAKRFCQYVVKQSELKGTFKGHKCSPCDTNWRYYGDSCYGFFRHNL 88
Query: 157 SWEDCKYFCLSENSTMLKINKQEDLEFAASQSYSEFFYSYWTGLLRPDSGKAWLWMDGTP 216
+WE+ K +C N+T+LKI+ + +E+ ++++ W GL R S + W W DG+
Sbjct: 89 TWEESKQYCTDMNATLLKIDNRNIVEYIKARTH----LIRWVGLSRQKSNEVWKWEDGSV 144
Query: 217 FTSELFHIIIDVTSPRSRDCVAILNGMIFSKDCKELKRCVCERRAGMVKPESL 269
+ +F + D + +C NG + C+ +CER+AGM K + L
Sbjct: 145 ISENMFEFLED--GKGNMNCAYFHNGKMHPTFCENKHYLMCERKAGMTKVDQL 195
>gi|94557293 myeloid inhibitory C-type lectin-like receptor isoform
beta [Homo sapiens]
Length = 232
Score = 106 bits (265), Expect = 2e-23
Identities = 66/185 (35%), Positives = 97/185 (52%), Gaps = 16/185 (8%)
Query: 92 RLGNTSQELQ---SLQVQ---NIK-----LAGSLQHVAEKLCRELYNKAGAHRCSPCTEQ 140
+L N S+ELQ SLQ+ NI L+ +LQ +A KLCRELY+K H+C PC +
Sbjct: 44 KLQNISEELQRNISLQLMSNMNISNKIRNLSTTLQTIATKLCRELYSKEQEHKCKPCPRR 103
Query: 141 WKWHGDNCYQFYKDSKSWEDCKYFCLSENSTMLKINKQEDLEFAASQSYSEFFYSYWTGL 200
W WH D+CY D ++W++ K C ++N+++LKIN + LEF SQS S Y YW GL
Sbjct: 104 WIWHKDSCYFLSDDVQTWQESKMACAAQNASLLKINNKNALEFIKSQSRS---YDYWLGL 160
Query: 201 LRPDSGKAWLWMDGTPFTSELFHIIIDVTSPRSRDCVAILNGMIFSKDCKELKRCVCERR 260
+ + +D +S +I + + C I + C KR +CE+
Sbjct: 161 SPEEDSTRGMRVDNIINSSA--WVIRNAPDLNNMYCGYINRLYVQYYHCTYKKRMICEKM 218
Query: 261 AGMVK 265
A V+
Sbjct: 219 ANPVQ 223
>gi|37675373 dendritic cell-associated C-type lectin 1 isoform a
[Homo sapiens]
Length = 247
Score = 105 bits (263), Expect = 3e-23
Identities = 78/264 (29%), Positives = 113/264 (42%), Gaps = 22/264 (8%)
Query: 4 KYSSTRDMLDDDGDTTMSLHSQGSATTRHPEPRRTEHRAPSSTWRPVALTLLTLCLVLLI 63
+Y + LD+DG T LH + TR A S WR +A+ L LCLV+L+
Sbjct: 2 EYHPDLENLDEDGYT--QLHFDSQSNTRIAVVSEKGSCAASPPWRLIAVILGILCLVILV 59
Query: 64 GLAALGLLFFQYYQLSNTGQDTISQ---MEERLGNTSQELQSLQVQNIKLAGSLQHVAEK 120
LG + SN+G +T+ + N SQ QS ++ ++
Sbjct: 60 IAVVLGTMAIWR---SNSGSNTLENGYFLSRNKENHSQPTQSSLEDSVTPTKAV------ 110
Query: 121 LCRELYNKAGAHRCSPCTEQWKWHGDNCYQFYKDSKSWEDCKYFCLSENSTMLKINKQED 180
K SPC W + +CY F SW+ K C S +LKI+ +
Sbjct: 111 -------KTTGVLSSPCPPNWIIYEKSCYLFSMSLNSWDGSKRQCWQLGSNLLKIDSSNE 163
Query: 181 LEFAASQSYSEFFYSYWTGLLRPDSGKAWLWMDGTPFTSELFHIIIDVTSPR-SRDCVAI 239
L F Q S+ S+W GL RP + WLW DG+ F+S LF I T S +CV I
Sbjct: 164 LGFIVKQVSSQPDNSFWIGLSRPQTEVPWLWEDGSTFSSNLFQIRTTATQENPSPNCVWI 223
Query: 240 LNGMIFSKDCKELKRCVCERRAGM 263
+I+ + C +CE++ M
Sbjct: 224 HVSVIYDQLCSVPSYSICEKKFSM 247
>gi|37675379 dendritic cell-associated C-type lectin 1 isoform e
[Homo sapiens]
Length = 168
Score = 84.0 bits (206), Expect = 1e-16
Identities = 45/130 (34%), Positives = 63/130 (48%), Gaps = 1/130 (0%)
Query: 135 SPCTEQWKWHGDNCYQFYKDSKSWEDCKYFCLSENSTMLKINKQEDLEFAASQSYSEFFY 194
SPC W + +CY F SW+ K C S +LKI+ +L F Q S+
Sbjct: 39 SPCPPNWIIYEKSCYLFSMSLNSWDGSKRQCWQLGSNLLKIDSSNELGFIVKQVSSQPDN 98
Query: 195 SYWTGLLRPDSGKAWLWMDGTPFTSELFHIIIDVTSPR-SRDCVAILNGMIFSKDCKELK 253
S+W GL RP + WLW DG+ F+S LF I T S +CV I +I+ + C
Sbjct: 99 SFWIGLSRPQTEVPWLWEDGSTFSSNLFQIRTTATQENPSPNCVWIHVSVIYDQLCSVPS 158
Query: 254 RCVCERRAGM 263
+CE++ M
Sbjct: 159 YSICEKKFSM 168
>gi|13384604 dendritic cell-associated C-type lectin 1 isoform b
[Homo sapiens]
Length = 201
Score = 84.0 bits (206), Expect = 1e-16
Identities = 45/130 (34%), Positives = 63/130 (48%), Gaps = 1/130 (0%)
Query: 135 SPCTEQWKWHGDNCYQFYKDSKSWEDCKYFCLSENSTMLKINKQEDLEFAASQSYSEFFY 194
SPC W + +CY F SW+ K C S +LKI+ +L F Q S+
Sbjct: 72 SPCPPNWIIYEKSCYLFSMSLNSWDGSKRQCWQLGSNLLKIDSSNELGFIVKQVSSQPDN 131
Query: 195 SYWTGLLRPDSGKAWLWMDGTPFTSELFHIIIDVTSPR-SRDCVAILNGMIFSKDCKELK 253
S+W GL RP + WLW DG+ F+S LF I T S +CV I +I+ + C
Sbjct: 132 SFWIGLSRPQTEVPWLWEDGSTFSSNLFQIRTTATQENPSPNCVWIHVSVIYDQLCSVPS 191
Query: 254 RCVCERRAGM 263
+CE++ M
Sbjct: 192 YSICEKKFSM 201
Score = 35.8 bits (81), Expect = 0.043
Identities = 23/68 (33%), Positives = 32/68 (47%), Gaps = 2/68 (2%)
Query: 4 KYSSTRDMLDDDGDTTMSLHSQGSATTRHPEPRRTEHRAPSSTWRPVALTLLTLCLVLLI 63
+Y + LD+DG T LH + TR A S WR +A+ L LCLV+L+
Sbjct: 2 EYHPDLENLDEDGYT--QLHFDSQSNTRIAVVSEKGSCAASPPWRLIAVILGILCLVILV 59
Query: 64 GLAALGLL 71
LG +
Sbjct: 60 IAVVLGTM 67
>gi|46409326 C-type lectin domain family 9, member A [Homo sapiens]
Length = 241
Score = 78.2 bits (191), Expect = 8e-15
Identities = 51/205 (24%), Positives = 91/205 (44%), Gaps = 13/205 (6%)
Query: 58 CLVLLIGLAALGLLFFQYYQLSNTGQDTISQMEERLGNTSQELQSLQVQNIKLAGSLQHV 117
C+ LL LG+ Q ++ Q+ + Q E L N ++ +S +Q +Q+
Sbjct: 44 CMGLLTASIFLGVKLLQVSTIAMQQQEKLIQQERALLNFTEWKRSCALQMKYCQAFMQN- 102
Query: 118 AEKLCRELYNKAGAHRCSPCTEQWKWHGDNCYQFYKDSKSWEDCKYFCLSENSTMLKINK 177
+ + AH SPC W + ++CY + W + CL E ST+L+I
Sbjct: 103 ---------SLSSAHNSSPCPNNWIQNRESCYYVSEIWSIWHTSQENCLKEGSTLLQIES 153
Query: 178 QEDLEF-AASQSYSEFFYSYWTGLLRPDSGKAWLWMDGTPFTSELFHIIIDVTSPRSRDC 236
+E+++F S + Y YW GL + WLW DG+ + L + + + ++ C
Sbjct: 154 KEEMDFITGSLRKIKGSYDYWVGLSQDGHSGRWLWQDGSSPSPGL--LPAERSQSANQVC 211
Query: 237 VAILNGMIFSKDCKELKRCVCERRA 261
+ + + S +C K +CE+ A
Sbjct: 212 GYVKSNSLLSSNCSTWKYFICEKYA 236
>gi|7705574 killer cell lectin-like receptor subfamily F, member 1
[Homo sapiens]
Length = 231
Score = 74.7 bits (182), Expect = 8e-14
Identities = 58/206 (28%), Positives = 88/206 (42%), Gaps = 26/206 (12%)
Query: 54 LLTLCLVLLIGLAALGLLF-FQYYQLSNTGQDTISQMEERLGNTSQELQSLQVQNIKLAG 112
+LTL L+ LI L + G+L Q SN Q ++ L+V N G
Sbjct: 50 ILTLTLISLILLVSQGVLLKCQKGSCSNATQ-------------YEDTGDLKVNN----G 92
Query: 113 SLQHVAEKLCRELYNKAGAHRCSPCTEQWKWHGDNCYQFYKDSKSWEDCKYFCLSENSTM 172
+ ++++ K +L A + C +W + CY F + KSW D +CL S +
Sbjct: 93 TRRNISNK---DLCASRSADQTVLCQSEWLKYQGKCYWFSNEMKSWSDSYVYCLERKSHL 149
Query: 173 LKINKQEDLEFAASQSYSEFFYSYWTGLLRPDSGKAWLWMDGTPFTSELFHIIIDVTSPR 232
L I+ Q LE A Q W GL W W+DG+P S++F I +
Sbjct: 150 LIIHDQ--LEMAFIQKNLRQLNYVWIGLNFTSLKMTWTWVDGSPIDSKIFFI---KGPAK 204
Query: 233 SRDCVAILNGMIFSKDCKELKRCVCE 258
C AI IFS+ C + + +C+
Sbjct: 205 ENSCAAIKESKIFSETCSSVFKWICQ 230
>gi|167614498 killer cell lectin-like receptor subfamily D, member 1
isoform 1 [Homo sapiens]
Length = 179
Score = 74.3 bits (181), Expect = 1e-13
Identities = 36/128 (28%), Positives = 69/128 (53%), Gaps = 9/128 (7%)
Query: 134 CSPCTEQWKWHGDNCYQFYKDSKSWEDCKYFCLSENSTMLKINKQEDLEFAASQSYSEFF 193
C C E+W + NCY + K+W + ++ C S+ S++L++ ++L+F +S S+ F
Sbjct: 58 CCSCQEKWVGYRCNCYFISSEQKTWNESRHLCASQKSSLLQLQNTDELDFMSS---SQQF 114
Query: 194 YSYWTGLLRPDSGKAWLWMDGTPFTSELFHIIIDVTSPRSRDCVAI-LNGMIFSKDCKEL 252
YW GL + AWLW +G+ + LF + +++C+A NG + C++
Sbjct: 115 --YWIGLSYSEEHTAWLWENGSALSQYLFP---SFETFNTKNCIAYNPNGNALDESCEDK 169
Query: 253 KRCVCERR 260
R +C+++
Sbjct: 170 NRYICKQQ 177
>gi|7669499 killer cell lectin-like receptor subfamily D, member 1
isoform 2 [Homo sapiens]
Length = 148
Score = 74.3 bits (181), Expect = 1e-13
Identities = 36/128 (28%), Positives = 69/128 (53%), Gaps = 9/128 (7%)
Query: 134 CSPCTEQWKWHGDNCYQFYKDSKSWEDCKYFCLSENSTMLKINKQEDLEFAASQSYSEFF 193
C C E+W + NCY + K+W + ++ C S+ S++L++ ++L+F +S S+ F
Sbjct: 27 CCSCQEKWVGYRCNCYFISSEQKTWNESRHLCASQKSSLLQLQNTDELDFMSS---SQQF 83
Query: 194 YSYWTGLLRPDSGKAWLWMDGTPFTSELFHIIIDVTSPRSRDCVAI-LNGMIFSKDCKEL 252
YW GL + AWLW +G+ + LF + +++C+A NG + C++
Sbjct: 84 --YWIGLSYSEEHTAWLWENGSALSQYLFP---SFETFNTKNCIAYNPNGNALDESCEDK 138
Query: 253 KRCVCERR 260
R +C+++
Sbjct: 139 NRYICKQQ 146
>gi|4504889 killer cell lectin-like receptor subfamily D, member 1
isoform 1 [Homo sapiens]
Length = 179
Score = 74.3 bits (181), Expect = 1e-13
Identities = 36/128 (28%), Positives = 69/128 (53%), Gaps = 9/128 (7%)
Query: 134 CSPCTEQWKWHGDNCYQFYKDSKSWEDCKYFCLSENSTMLKINKQEDLEFAASQSYSEFF 193
C C E+W + NCY + K+W + ++ C S+ S++L++ ++L+F +S S+ F
Sbjct: 58 CCSCQEKWVGYRCNCYFISSEQKTWNESRHLCASQKSSLLQLQNTDELDFMSS---SQQF 114
Query: 194 YSYWTGLLRPDSGKAWLWMDGTPFTSELFHIIIDVTSPRSRDCVAI-LNGMIFSKDCKEL 252
YW GL + AWLW +G+ + LF + +++C+A NG + C++
Sbjct: 115 --YWIGLSYSEEHTAWLWENGSALSQYLFP---SFETFNTKNCIAYNPNGNALDESCEDK 169
Query: 253 KRCVCERR 260
R +C+++
Sbjct: 170 NRYICKQQ 177
>gi|169234653 NKG2-D type II integral membrane protein [Homo
sapiens]
Length = 216
Score = 71.2 bits (173), Expect = 9e-13
Identities = 37/129 (28%), Positives = 65/129 (50%), Gaps = 12/129 (9%)
Query: 134 CSPCTEQWKWHGDNCYQFYKDSKSWEDCKYFCLSENSTMLKINKQEDLEFAASQSYSEFF 193
C PC + W + +NCYQF+ +SK+W + + C+S+N+++LK+ +ED Q +
Sbjct: 96 CGPCPKNWICYKNNCYQFFDESKNWYESQASCMSQNASLLKVYSKED------QDLLKLV 149
Query: 194 YSY-WTGLLRPDSGKAWLWMDGTPFTSELFHIIIDVTSPRSRDCVAILNGMI-FSKDCKE 251
SY W GL+ + +W W DG+ + L II + DC + + ++C
Sbjct: 150 KSYHWMGLVHIPTNGSWQWEDGSILSPNLLTII----EMQKGDCALYASSFKGYIENCST 205
Query: 252 LKRCVCERR 260
+C +R
Sbjct: 206 PNTYICMQR 214
>gi|7705338 C-type lectin domain family 4, member A isoform 1 [Homo
sapiens]
Length = 237
Score = 67.0 bits (162), Expect = 2e-11
Identities = 62/240 (25%), Positives = 103/240 (42%), Gaps = 39/240 (16%)
Query: 27 SATTRHPEPRRTEHRAPSSTWRPVALTLLTLCLVLLIGLAALGLLFFQYYQLSNTGQDTI 86
+A++ + R H++ + + + +LL L+L I ++FFQ Y
Sbjct: 23 TASSAASKERTAPHKSNTGFPKLLCASLLIFFLLLAISFFIAFVIFFQKY---------- 72
Query: 87 SQMEERLGNTSQELQSLQVQNIKLAGSLQHVAEKLCRELYNKAGAHRCSPCTEQWKWHGD 146
SQ+ E+ T++EL ++ +K ++ A S C + WK
Sbjct: 73 SQLLEK--KTTKELVHTTLECVKKNMPVEETA---------------WSCCPKNWKSFSS 115
Query: 147 NCYQFYKDSKSWEDCKYFCLSENSTMLKINKQEDLEFAASQSYSEFFYSYWTGLLRPDSG 206
NCY +S SW+D + C + +L IN QE+ +F E +Y+ GL P+
Sbjct: 116 NCYFISTESASWQDSEKDCARMEAHLLVINTQEEQDFIFQNLQEE--SAYFVGLSDPEGQ 173
Query: 207 KAWLWMDGTPFT-SELFHIIIDVTSPRSRDCVAILNGMIFSK-------DCKELKRCVCE 258
+ W W+D TP+ S F + + P R CV +LN K +C +R VCE
Sbjct: 174 RHWQWVDQTPYNESSTFWHPREPSDPNER-CV-VLNFRKSPKRWGWNDVNCLGPQRSVCE 231
>gi|75709169 killer cell lectin-like receptor subfamily C, member 2
[Homo sapiens]
Length = 231
Score = 65.1 bits (157), Expect = 7e-11
Identities = 33/114 (28%), Positives = 57/114 (50%), Gaps = 13/114 (11%)
Query: 131 AHRCSPCTEQWKWHGDNCYQFYKDSKSWEDCKYFCLSENSTMLKINKQEDLEFAASQSYS 190
A C C E+W + ++CY K+ ++WE+ C S+NS++L I+ +E+++F AS
Sbjct: 111 ARHCGHCPEEWITYSNSCYYIGKERRTWEESLLACTSKNSSLLSIDNEEEMKFLAS---- 166
Query: 191 EFFYSYWTGLLRPDSGKAWLWMDGTPF--------TSELFHIIIDVTSPRSRDC 236
S W G+ R S W+ ++G F +EL ++ V +S C
Sbjct: 167 -ILPSSWIGVFRNSSHHPWVTINGLAFKHKIKDSDNAELNCAVLQVNRLKSAQC 219
>gi|47717094 killer cell lectin-like receptor subfamily C, member 1
isoform NKG2-A [Homo sapiens]
Length = 233
Score = 65.1 bits (157), Expect = 7e-11
Identities = 29/91 (31%), Positives = 50/91 (54%), Gaps = 5/91 (5%)
Query: 131 AHRCSPCTEQWKWHGDNCYQFYKDSKSWEDCKYFCLSENSTMLKINKQEDLEFAASQSYS 190
A C C E+W + ++CY K+ ++WE+ C S+NS++L I+ +E+++F + S S
Sbjct: 113 ARHCGHCPEEWITYSNSCYYIGKERRTWEESLLACTSKNSSLLSIDNEEEMKFLSIISPS 172
Query: 191 EFFYSYWTGLLRPDSGKAWLWMDGTPFTSEL 221
W G+ R S W+ M+G F E+
Sbjct: 173 S-----WIGVFRNSSHHPWVTMNGLAFKHEI 198
>gi|4504881 killer cell lectin-like receptor subfamily C, member 1
isoform NKG2-A [Homo sapiens]
Length = 233
Score = 65.1 bits (157), Expect = 7e-11
Identities = 29/91 (31%), Positives = 50/91 (54%), Gaps = 5/91 (5%)
Query: 131 AHRCSPCTEQWKWHGDNCYQFYKDSKSWEDCKYFCLSENSTMLKINKQEDLEFAASQSYS 190
A C C E+W + ++CY K+ ++WE+ C S+NS++L I+ +E+++F + S S
Sbjct: 113 ARHCGHCPEEWITYSNSCYYIGKERRTWEESLLACTSKNSSLLSIDNEEEMKFLSIISPS 172
Query: 191 EFFYSYWTGLLRPDSGKAWLWMDGTPFTSEL 221
W G+ R S W+ M+G F E+
Sbjct: 173 S-----WIGVFRNSSHHPWVTMNGLAFKHEI 198
>gi|18426877 asialoglycoprotein receptor 2 isoform c [Homo sapiens]
Length = 292
Score = 64.3 bits (155), Expect = 1e-10
Identities = 53/192 (27%), Positives = 87/192 (45%), Gaps = 26/192 (13%)
Query: 84 DTISQMEERLGNTSQELQSLQVQNIKLAGSLQHVAEKL----CR-ELYNKAGAHRCSPCT 138
D I+ + +L ++ Q L+ + L L+H L C+ EL + G+ R C
Sbjct: 104 DKITSLGAKL---EKQQQDLKADHDALLFHLKHFPVDLRFVACQMELLHSNGSQRTC-CP 159
Query: 139 EQWKWHGDNCYQFYKDSKSWEDCKYFCLSENSTMLKINKQEDLEFAASQSYSEFFYSYWT 198
W H +CY F K+W + + +C EN+ ++ IN E+ +F + ++ W
Sbjct: 160 VNWVEHQGSCYWFSHSGKAWAEAEKYCQLENAHLVVINSWEEQKFIVQHTNP---FNTWI 216
Query: 199 GLLRPDSGKAWLWMDGTPFTSELFHIIIDVTSP---------RSRDCVAILNGMIFSKD- 248
GL DS +W W+DGT + + VT P S DCV + ++ D
Sbjct: 217 GL--TDSDGSWKWVDGTDYRHNYKNWA--VTQPDNWHGHELGGSEDCVEVQPDGRWNDDF 272
Query: 249 CKELKRCVCERR 260
C ++ R VCE+R
Sbjct: 273 CLQVYRWVCEKR 284
>gi|18426875 asialoglycoprotein receptor 2 isoform b [Homo sapiens]
Length = 287
Score = 64.3 bits (155), Expect = 1e-10
Identities = 53/192 (27%), Positives = 87/192 (45%), Gaps = 26/192 (13%)
Query: 84 DTISQMEERLGNTSQELQSLQVQNIKLAGSLQHVAEKL----CR-ELYNKAGAHRCSPCT 138
D I+ + +L ++ Q L+ + L L+H L C+ EL + G+ R C
Sbjct: 99 DKITSLGAKL---EKQQQDLKADHDALLFHLKHFPVDLRFVACQMELLHSNGSQRTC-CP 154
Query: 139 EQWKWHGDNCYQFYKDSKSWEDCKYFCLSENSTMLKINKQEDLEFAASQSYSEFFYSYWT 198
W H +CY F K+W + + +C EN+ ++ IN E+ +F + ++ W
Sbjct: 155 VNWVEHQGSCYWFSHSGKAWAEAEKYCQLENAHLVVINSWEEQKFIVQHTNP---FNTWI 211
Query: 199 GLLRPDSGKAWLWMDGTPFTSELFHIIIDVTSP---------RSRDCVAILNGMIFSKD- 248
GL DS +W W+DGT + + VT P S DCV + ++ D
Sbjct: 212 GL--TDSDGSWKWVDGTDYRHNYKNWA--VTQPDNWHGHELGGSEDCVEVQPDGRWNDDF 267
Query: 249 CKELKRCVCERR 260
C ++ R VCE+R
Sbjct: 268 CLQVYRWVCEKR 279
>gi|18426873 asialoglycoprotein receptor 2 isoform a [Homo sapiens]
Length = 311
Score = 64.3 bits (155), Expect = 1e-10
Identities = 53/192 (27%), Positives = 87/192 (45%), Gaps = 26/192 (13%)
Query: 84 DTISQMEERLGNTSQELQSLQVQNIKLAGSLQHVAEKL----CR-ELYNKAGAHRCSPCT 138
D I+ + +L ++ Q L+ + L L+H L C+ EL + G+ R C
Sbjct: 123 DKITSLGAKL---EKQQQDLKADHDALLFHLKHFPVDLRFVACQMELLHSNGSQRTC-CP 178
Query: 139 EQWKWHGDNCYQFYKDSKSWEDCKYFCLSENSTMLKINKQEDLEFAASQSYSEFFYSYWT 198
W H +CY F K+W + + +C EN+ ++ IN E+ +F + ++ W
Sbjct: 179 VNWVEHQGSCYWFSHSGKAWAEAEKYCQLENAHLVVINSWEEQKFIVQHTNP---FNTWI 235
Query: 199 GLLRPDSGKAWLWMDGTPFTSELFHIIIDVTSP---------RSRDCVAILNGMIFSKD- 248
GL DS +W W+DGT + + VT P S DCV + ++ D
Sbjct: 236 GL--TDSDGSWKWVDGTDYRHNYKNWA--VTQPDNWHGHELGGSEDCVEVQPDGRWNDDF 291
Query: 249 CKELKRCVCERR 260
C ++ R VCE+R
Sbjct: 292 CLQVYRWVCEKR 303
>gi|4502253 asialoglycoprotein receptor 2 isoform a [Homo sapiens]
Length = 311
Score = 64.3 bits (155), Expect = 1e-10
Identities = 53/192 (27%), Positives = 87/192 (45%), Gaps = 26/192 (13%)
Query: 84 DTISQMEERLGNTSQELQSLQVQNIKLAGSLQHVAEKL----CR-ELYNKAGAHRCSPCT 138
D I+ + +L ++ Q L+ + L L+H L C+ EL + G+ R C
Sbjct: 123 DKITSLGAKL---EKQQQDLKADHDALLFHLKHFPVDLRFVACQMELLHSNGSQRTC-CP 178
Query: 139 EQWKWHGDNCYQFYKDSKSWEDCKYFCLSENSTMLKINKQEDLEFAASQSYSEFFYSYWT 198
W H +CY F K+W + + +C EN+ ++ IN E+ +F + ++ W
Sbjct: 179 VNWVEHQGSCYWFSHSGKAWAEAEKYCQLENAHLVVINSWEEQKFIVQHTNP---FNTWI 235
Query: 199 GLLRPDSGKAWLWMDGTPFTSELFHIIIDVTSP---------RSRDCVAILNGMIFSKD- 248
GL DS +W W+DGT + + VT P S DCV + ++ D
Sbjct: 236 GL--TDSDGSWKWVDGTDYRHNYKNWA--VTQPDNWHGHELGGSEDCVEVQPDGRWNDDF 291
Query: 249 CKELKRCVCERR 260
C ++ R VCE+R
Sbjct: 292 CLQVYRWVCEKR 303
>gi|47717092 killer cell lectin-like receptor subfamily C, member 1
isoform NKG2-B [Homo sapiens]
Length = 215
Score = 63.9 bits (154), Expect = 1e-10
Identities = 28/91 (30%), Positives = 50/91 (54%), Gaps = 5/91 (5%)
Query: 131 AHRCSPCTEQWKWHGDNCYQFYKDSKSWEDCKYFCLSENSTMLKINKQEDLEFAASQSYS 190
+ C C E+W + ++CY K+ ++WE+ C S+NS++L I+ +E+++F + S S
Sbjct: 95 SRHCGHCPEEWITYSNSCYYIGKERRTWEESLLACTSKNSSLLSIDNEEEMKFLSIISPS 154
Query: 191 EFFYSYWTGLLRPDSGKAWLWMDGTPFTSEL 221
W G+ R S W+ M+G F E+
Sbjct: 155 S-----WIGVFRNSSHHPWVTMNGLAFKHEI 180
>gi|7262384 killer cell lectin-like receptor subfamily C, member 1
isoform NKG2-B [Homo sapiens]
Length = 215
Score = 63.9 bits (154), Expect = 1e-10
Identities = 28/91 (30%), Positives = 50/91 (54%), Gaps = 5/91 (5%)
Query: 131 AHRCSPCTEQWKWHGDNCYQFYKDSKSWEDCKYFCLSENSTMLKINKQEDLEFAASQSYS 190
+ C C E+W + ++CY K+ ++WE+ C S+NS++L I+ +E+++F + S S
Sbjct: 95 SRHCGHCPEEWITYSNSCYYIGKERRTWEESLLACTSKNSSLLSIDNEEEMKFLSIISPS 154
Query: 191 EFFYSYWTGLLRPDSGKAWLWMDGTPFTSEL 221
W G+ R S W+ M+G F E+
Sbjct: 155 S-----WIGVFRNSSHHPWVTMNGLAFKHEI 180
>gi|37577119 C-type lectin domain family 4, member A isoform 2 [Homo
sapiens]
Length = 204
Score = 60.8 bits (146), Expect = 1e-09
Identities = 42/132 (31%), Positives = 61/132 (46%), Gaps = 12/132 (9%)
Query: 135 SPCTEQWKWHGDNCYQFYKDSKSWEDCKYFCLSENSTMLKINKQEDLEFAASQSYSEFFY 194
S C + WK NCY +S SW+D + C + +L IN QE+ +F E
Sbjct: 71 SCCPKNWKSFSSNCYFISTESASWQDSEKDCARMEAHLLVINTQEEQDFIFQNLQEE--S 128
Query: 195 SYWTGLLRPDSGKAWLWMDGTPFT-SELFHIIIDVTSPRSRDCVAILNGMIFSK------ 247
+Y+ GL P+ + W W+D TP+ S F + + P R CV +LN K
Sbjct: 129 AYFVGLSDPEGQRHWQWVDQTPYNESSTFWHPREPSDPNER-CV-VLNFRKSPKRWGWND 186
Query: 248 -DCKELKRCVCE 258
+C +R VCE
Sbjct: 187 VNCLGPQRSVCE 198
>gi|37577117 C-type lectin domain family 4, member A isoform 4 [Homo
sapiens]
Length = 165
Score = 60.8 bits (146), Expect = 1e-09
Identities = 42/132 (31%), Positives = 61/132 (46%), Gaps = 12/132 (9%)
Query: 135 SPCTEQWKWHGDNCYQFYKDSKSWEDCKYFCLSENSTMLKINKQEDLEFAASQSYSEFFY 194
S C + WK NCY +S SW+D + C + +L IN QE+ +F E
Sbjct: 32 SCCPKNWKSFSSNCYFISTESASWQDSEKDCARMEAHLLVINTQEEQDFIFQNLQEE--S 89
Query: 195 SYWTGLLRPDSGKAWLWMDGTPFT-SELFHIIIDVTSPRSRDCVAILNGMIFSK------ 247
+Y+ GL P+ + W W+D TP+ S F + + P R CV +LN K
Sbjct: 90 AYFVGLSDPEGQRHWQWVDQTPYNESSTFWHPREPSDPNER-CV-VLNFRKSPKRWGWND 147
Query: 248 -DCKELKRCVCE 258
+C +R VCE
Sbjct: 148 VNCLGPQRSVCE 159
>gi|148536836 C-type lectin domain family 4, member A isoform 3
[Homo sapiens]
Length = 198
Score = 60.8 bits (146), Expect = 1e-09
Identities = 42/132 (31%), Positives = 61/132 (46%), Gaps = 12/132 (9%)
Query: 135 SPCTEQWKWHGDNCYQFYKDSKSWEDCKYFCLSENSTMLKINKQEDLEFAASQSYSEFFY 194
S C + WK NCY +S SW+D + C + +L IN QE+ +F E
Sbjct: 65 SCCPKNWKSFSSNCYFISTESASWQDSEKDCARMEAHLLVINTQEEQDFIFQNLQEE--S 122
Query: 195 SYWTGLLRPDSGKAWLWMDGTPFT-SELFHIIIDVTSPRSRDCVAILNGMIFSK------ 247
+Y+ GL P+ + W W+D TP+ S F + + P R CV +LN K
Sbjct: 123 AYFVGLSDPEGQRHWQWVDQTPYNESSTFWHPREPSDPNER-CV-VLNFRKSPKRWGWND 180
Query: 248 -DCKELKRCVCE 258
+C +R VCE
Sbjct: 181 VNCLGPQRSVCE 192
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.132 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,671,485
Number of Sequences: 37866
Number of extensions: 508089
Number of successful extensions: 1875
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 93
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 1638
Number of HSP's gapped (non-prelim): 154
length of query: 280
length of database: 18,247,518
effective HSP length: 101
effective length of query: 179
effective length of database: 14,423,052
effective search space: 2581726308
effective search space used: 2581726308
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.