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Search of human proteins with 37537552
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|37537552 sodium-dependent organic anion transporter [Homo
sapiens]
(377 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|37537552 sodium-dependent organic anion transporter [Homo sap... 766 0.0
gi|4506973 solute carrier family 10 (sodium/bile acid cotranspor... 332 4e-91
gi|4506971 solute carrier family 10, member 1 [Homo sapiens] 209 3e-54
gi|24308414 solute carrier family 10, member 4 [Homo sapiens] 206 2e-53
gi|215422370 solute carrier family 10, member 3 isoform 1 [Homo ... 129 6e-30
gi|215422368 solute carrier family 10, member 3 isoform 2 [Homo ... 129 6e-30
gi|9790143 solute carrier family 10, member 3 isoform 1 [Homo sa... 129 6e-30
gi|58219066 solute carrier family 10 (sodium/bile acid cotranspo... 125 6e-29
gi|116256358 secretory carrier membrane protein 1 [Homo sapiens] 34 0.19
gi|110347437 latent transforming growth factor beta binding prot... 30 4.6
gi|50080197 olfactory receptor, family 13, subfamily C, member 9... 29 7.9
>gi|37537552 sodium-dependent organic anion transporter [Homo
sapiens]
Length = 377
Score = 766 bits (1979), Expect = 0.0
Identities = 377/377 (100%), Positives = 377/377 (100%)
Query: 1 MRANCSSSSACPANSSEEELPVGLEVHGNLELVFTVVSTVMMGLLMFSLGCSVEIRKLWS 60
MRANCSSSSACPANSSEEELPVGLEVHGNLELVFTVVSTVMMGLLMFSLGCSVEIRKLWS
Sbjct: 1 MRANCSSSSACPANSSEEELPVGLEVHGNLELVFTVVSTVMMGLLMFSLGCSVEIRKLWS 60
Query: 61 HIRRPWGIAVGLLCQFGLMPFTAYLLAISFSLKPVQAIAVLIMGCCPGGTISNIFTFWVD 120
HIRRPWGIAVGLLCQFGLMPFTAYLLAISFSLKPVQAIAVLIMGCCPGGTISNIFTFWVD
Sbjct: 61 HIRRPWGIAVGLLCQFGLMPFTAYLLAISFSLKPVQAIAVLIMGCCPGGTISNIFTFWVD 120
Query: 121 GDMDLSISMTTCSTVAALGMMPLCIYLYTWSWSLQQNLTIPYQNIGITLVCLTIPVAFGV 180
GDMDLSISMTTCSTVAALGMMPLCIYLYTWSWSLQQNLTIPYQNIGITLVCLTIPVAFGV
Sbjct: 121 GDMDLSISMTTCSTVAALGMMPLCIYLYTWSWSLQQNLTIPYQNIGITLVCLTIPVAFGV 180
Query: 181 YVNYRWPKQSKIILKIGAVVGGVLLLVVAVAGVVLAKGSWNSDITLLTISFIFPLIGHVT 240
YVNYRWPKQSKIILKIGAVVGGVLLLVVAVAGVVLAKGSWNSDITLLTISFIFPLIGHVT
Sbjct: 181 YVNYRWPKQSKIILKIGAVVGGVLLLVVAVAGVVLAKGSWNSDITLLTISFIFPLIGHVT 240
Query: 241 GFLLALFTHQSWQRCRTISLETGAQNIQMCITMLQLSFTAEHLVQMLSFPLAYGLFQLID 300
GFLLALFTHQSWQRCRTISLETGAQNIQMCITMLQLSFTAEHLVQMLSFPLAYGLFQLID
Sbjct: 241 GFLLALFTHQSWQRCRTISLETGAQNIQMCITMLQLSFTAEHLVQMLSFPLAYGLFQLID 300
Query: 301 GFLIVAAYQTYKRRLKNKHGKKNSGCTEVCHTRKSTSSRETNAFLEVNEEGAITPGPPGP 360
GFLIVAAYQTYKRRLKNKHGKKNSGCTEVCHTRKSTSSRETNAFLEVNEEGAITPGPPGP
Sbjct: 301 GFLIVAAYQTYKRRLKNKHGKKNSGCTEVCHTRKSTSSRETNAFLEVNEEGAITPGPPGP 360
Query: 361 MDCHRALEPVGHITSCE 377
MDCHRALEPVGHITSCE
Sbjct: 361 MDCHRALEPVGHITSCE 377
>gi|4506973 solute carrier family 10 (sodium/bile acid cotransporter
family), member 2 [Homo sapiens]
Length = 348
Score = 332 bits (850), Expect = 4e-91
Identities = 154/319 (48%), Positives = 219/319 (68%), Gaps = 8/319 (2%)
Query: 30 LELVFTVVSTVMMGLLMFSLGCSVEIRKLWSHIRRPWGIAVGLLCQFGLMPFTAYLLAIS 89
L +V + V T+++ L+MFS+GC+VEI+K HI+RPWGI VG LCQFG+MP T ++L+++
Sbjct: 30 LSVVLSTVLTILLALVMFSMGCNVEIKKFLGHIKRPWGICVGFLCQFGIMPLTGFILSVA 89
Query: 90 FSLKPVQAIAVLIMGCCPGGTISNIFTFWVDGDMDLSISMTTCSTVAALGMMPLCIYLYT 149
F + P+QA+ VLI+GCCPGGT SNI +WVDGDMDLS+SMTTCST+ ALGMMPLC+ +YT
Sbjct: 90 FDILPLQAVVVLIIGCCPGGTASNILAYWVDGDMDLSVSMTTCSTLLALGMMPLCLLIYT 149
Query: 150 WSWSLQQNLTIPYQNIGITLVCLTIPVAFGVYVNYRWPKQSKIILKIGAVVGGVLLLVVA 209
W ++ IPY NIG +LV L +PV+ G++VN++WP+++KIILKIG++ G +L++++A
Sbjct: 150 KMWVDSGSIVIPYDNIGTSLVALVVPVSIGMFVNHKWPQKAKIILKIGSIAGAILIVLIA 209
Query: 210 VAGVVLAKGSWNSDITLLTISFIFPLIGHVTGFLLALFTHQSWQRCRTISLETGAQNIQM 269
V G +L + +W L I IFP+ G+ GFLLA W RCRT++ ETG QN Q+
Sbjct: 210 VVGGILYQSAWIIAPKLWIIGTIFPVAGYSLGFLLARIAGLPWYRCRTVAFETGMQNTQL 269
Query: 270 CITMLQLSFTAEHLVQMLSFPLAYGLFQLIDGFLIVAAYQTYKRRLKNKHGKKNSGCTEV 329
C T++QLSFT E L + +FPL Y +FQL + + Y YK+ HGK + E
Sbjct: 270 CSTIVQLSFTPEELNVVFTFPLIYSIFQLAFAAIFLGFYVAYKK----CHGKNKAEIPE- 324
Query: 330 CHTRKSTSSRETNAFLEVN 348
K + ++F + N
Sbjct: 325 ---SKENGTEPESSFYKAN 340
>gi|4506971 solute carrier family 10, member 1 [Homo sapiens]
Length = 349
Score = 209 bits (532), Expect = 3e-54
Identities = 108/292 (36%), Positives = 183/292 (62%), Gaps = 15/292 (5%)
Query: 31 ELVFTVVSTVMMGLLMFSLGCSVEIRKLWSHIRRPWGIAVGLLCQFGLMPFTAYLLAISF 90
+L +V+ M+ +M SLGC++E K+ +H+ +P G+A+ L+ Q+G+MP TA++L F
Sbjct: 24 DLALSVILVFMLFFIMLSLGCTMEFSKIKAHLWKPKGLAIALVAQYGIMPLTAFVLGKVF 83
Query: 91 SLKPVQAIAVLIMGCCPGGTISNIFTFWVDGDMDLSISMTTCSTVAALGMMPLCIYLYT- 149
LK ++A+A+L+ GC PGG +SN+F+ + GDM+LSI MTTCST ALGMMPL +Y+Y+
Sbjct: 84 RLKNIEALAILVCGCSPGGNLSNVFSLAMKGDMNLSIVMTTCSTFCALGMMPLLLYIYSR 143
Query: 150 --WSWSLQQNLTIPYQNIGITLVCLTIPVAFGVYVNYRWPKQSKIILKIGAVVGGVLLLV 207
+ L+ +PY+ I I+LV + IP G+ + + P+ + ++K G ++ +L+
Sbjct: 144 GIYDGDLKDK--VPYKGIVISLVLVLIPCTIGIVLKSKRPQYMRYVIKGGMII----ILL 197
Query: 208 VAVAGVVLAKGSWNSDI------TLLTISFIFPLIGHVTGFLLALFTHQSWQRCRTISLE 261
+VA VL+ + I L+ S + P IG + G++L+ + + RT+S+E
Sbjct: 198 CSVAVTVLSAINVGKSIMFAMTPLLIATSSLMPFIGFLLGYVLSALFCLNGRCRRTVSME 257
Query: 262 TGAQNIQMCITMLQLSFTAEHLVQMLSFPLAYGLFQLIDGFLIVAAYQTYKR 313
TG QN+Q+C T+L ++F E + + FPL Y +FQL +G L++A + Y++
Sbjct: 258 TGCQNVQLCSTILNVAFPPEVIGPLFFFPLLYMIFQLGEGLLLIAIFWCYEK 309
>gi|24308414 solute carrier family 10, member 4 [Homo sapiens]
Length = 437
Score = 206 bits (525), Expect = 2e-53
Identities = 106/278 (38%), Positives = 166/278 (59%), Gaps = 3/278 (1%)
Query: 44 LLMFSLGCSVEIRKLWSHIRRPWGIAVGLLCQFGLMPFTAYLLAISFSLKPVQAIAVLIM 103
+ M LGC+V++ +H+RRP G + LCQFGL+P A+LLA++F L V A+AVL+
Sbjct: 115 ITMLGLGCTVDVNHFGAHVRRPVGALLAALCQFGLLPLLAFLLALAFKLDEVAAVAVLLC 174
Query: 104 GCCPGGTISNIFTFWVDGDMDLSISMTTCSTVAALGMMPLCIYLYTWSW-SLQQNLTIPY 162
GCCPGG +SN+ + VDGDM+LSI MT ST+ AL +MPLC+++Y+W+W + +P
Sbjct: 175 GCCPGGNLSNLMSLLVDGDMNLSIIMTISSTLLALVLMPLCLWIYSWAWINTPIVQLLPL 234
Query: 163 QNIGITLVCLTIPVAFGVYVNYRWPKQSKIILKIGAVVGGVLLLVVAV-AGVVLAKGSWN 221
+ +TL IP+ GV++ Y++ + + I+K+ V L+V+ + G +L
Sbjct: 235 GTVTLTLCSTLIPIGLGVFIRYKYSRVADYIVKVSLWSLLVTLVVLFIMTGTMLGPELLA 294
Query: 222 S-DITLLTISFIFPLIGHVTGFLLALFTHQSWQRCRTISLETGAQNIQMCITMLQLSFTA 280
S + I+ PL G+ +G+ LA H RT+ LETG+QN+Q+C +L+L+F
Sbjct: 295 SIPAAVYVIAIFMPLAGYASGYGLATLFHLPPNCKRTVCLETGSQNVQLCTAILKLAFPP 354
Query: 281 EHLVQMLSFPLAYGLFQLIDGFLIVAAYQTYKRRLKNK 318
+ + M FPL Y LFQ + + V Y+ Y + +K
Sbjct: 355 QFIGSMYMFPLLYALFQSAEAGIFVLIYKMYGSEMLHK 392
>gi|215422370 solute carrier family 10, member 3 isoform 1 [Homo
sapiens]
Length = 477
Score = 129 bits (323), Expect = 6e-30
Identities = 82/234 (35%), Positives = 128/234 (54%), Gaps = 7/234 (2%)
Query: 48 SLGCSVEIRKLWSHIRRPWGIAVGLLCQFGLMPFTAYLLAISFSLKPVQAIAVLIMGCCP 107
S GC VE+ L ++ P + +GLL QF +MP A+L+A F L A+ ++I P
Sbjct: 206 SFGCKVELEVLKGLMQSPQPMLLGLLGQFLVMPLYAFLMAKVFMLPKALALGLIITCSSP 265
Query: 108 GGTISNIFTFWVDGDMDLSISMTTCSTVAALGMMPLCIYLYTWSWSLQQNLTIPYQNIGI 167
GG S +F+ + GD+ L+ISMT STVAA G +PL +Y+ S+ + L +P I
Sbjct: 266 GGGGSYLFSLLLGGDVTLAISMTFLSTVAATGFLPLSSAIYSRLLSIHETLHVPISKILG 325
Query: 168 TLVCLTIPVAFGVYVNYRWPKQSKIILKIGAVVGGVLLL----VVAVAGVVLAKGSWNSD 223
TL+ + IP+A GV + + PK S+++L++ VLLL + GV + G
Sbjct: 326 TLLFIAIPIAVGVLIKSKLPKFSQLLLQVVKPFSFVLLLGGLFLAYRMGVFILAG---IR 382
Query: 224 ITLLTISFIFPLIGHVTGFLLALFTHQSWQRCRTISLETGAQNIQMCITMLQLS 277
+ ++ + PL+G + G+ LA + RT+S+E G QN + + MLQLS
Sbjct: 383 LPIVLVGITVPLVGLLVGYCLATCLKLPVAQRRTVSIEVGVQNSLLALAMLQLS 436
>gi|215422368 solute carrier family 10, member 3 isoform 2 [Homo
sapiens]
Length = 448
Score = 129 bits (323), Expect = 6e-30
Identities = 82/234 (35%), Positives = 128/234 (54%), Gaps = 7/234 (2%)
Query: 48 SLGCSVEIRKLWSHIRRPWGIAVGLLCQFGLMPFTAYLLAISFSLKPVQAIAVLIMGCCP 107
S GC VE+ L ++ P + +GLL QF +MP A+L+A F L A+ ++I P
Sbjct: 177 SFGCKVELEVLKGLMQSPQPMLLGLLGQFLVMPLYAFLMAKVFMLPKALALGLIITCSSP 236
Query: 108 GGTISNIFTFWVDGDMDLSISMTTCSTVAALGMMPLCIYLYTWSWSLQQNLTIPYQNIGI 167
GG S +F+ + GD+ L+ISMT STVAA G +PL +Y+ S+ + L +P I
Sbjct: 237 GGGGSYLFSLLLGGDVTLAISMTFLSTVAATGFLPLSSAIYSRLLSIHETLHVPISKILG 296
Query: 168 TLVCLTIPVAFGVYVNYRWPKQSKIILKIGAVVGGVLLL----VVAVAGVVLAKGSWNSD 223
TL+ + IP+A GV + + PK S+++L++ VLLL + GV + G
Sbjct: 297 TLLFIAIPIAVGVLIKSKLPKFSQLLLQVVKPFSFVLLLGGLFLAYRMGVFILAG---IR 353
Query: 224 ITLLTISFIFPLIGHVTGFLLALFTHQSWQRCRTISLETGAQNIQMCITMLQLS 277
+ ++ + PL+G + G+ LA + RT+S+E G QN + + MLQLS
Sbjct: 354 LPIVLVGITVPLVGLLVGYCLATCLKLPVAQRRTVSIEVGVQNSLLALAMLQLS 407
>gi|9790143 solute carrier family 10, member 3 isoform 1 [Homo
sapiens]
Length = 477
Score = 129 bits (323), Expect = 6e-30
Identities = 82/234 (35%), Positives = 128/234 (54%), Gaps = 7/234 (2%)
Query: 48 SLGCSVEIRKLWSHIRRPWGIAVGLLCQFGLMPFTAYLLAISFSLKPVQAIAVLIMGCCP 107
S GC VE+ L ++ P + +GLL QF +MP A+L+A F L A+ ++I P
Sbjct: 206 SFGCKVELEVLKGLMQSPQPMLLGLLGQFLVMPLYAFLMAKVFMLPKALALGLIITCSSP 265
Query: 108 GGTISNIFTFWVDGDMDLSISMTTCSTVAALGMMPLCIYLYTWSWSLQQNLTIPYQNIGI 167
GG S +F+ + GD+ L+ISMT STVAA G +PL +Y+ S+ + L +P I
Sbjct: 266 GGGGSYLFSLLLGGDVTLAISMTFLSTVAATGFLPLSSAIYSRLLSIHETLHVPISKILG 325
Query: 168 TLVCLTIPVAFGVYVNYRWPKQSKIILKIGAVVGGVLLL----VVAVAGVVLAKGSWNSD 223
TL+ + IP+A GV + + PK S+++L++ VLLL + GV + G
Sbjct: 326 TLLFIAIPIAVGVLIKSKLPKFSQLLLQVVKPFSFVLLLGGLFLAYRMGVFILAG---IR 382
Query: 224 ITLLTISFIFPLIGHVTGFLLALFTHQSWQRCRTISLETGAQNIQMCITMLQLS 277
+ ++ + PL+G + G+ LA + RT+S+E G QN + + MLQLS
Sbjct: 383 LPIVLVGITVPLVGLLVGYCLATCLKLPVAQRRTVSIEVGVQNSLLALAMLQLS 436
>gi|58219066 solute carrier family 10 (sodium/bile acid
cotransporter family), member 5 [Homo sapiens]
Length = 438
Score = 125 bits (314), Expect = 6e-29
Identities = 77/292 (26%), Positives = 144/292 (49%), Gaps = 9/292 (3%)
Query: 26 VHGNLELVFTVVSTVMMGLLMFSLGCSVEIRKLWSHIRRPWGIAVGLLCQFGLMPFTAYL 85
+H + ++ ++ +++ F GC +E++ + +RP + +G + QF LMPF +L
Sbjct: 137 MHIDRNILMLILPLILLNKCAF--GCKIELQLFQTVWKRPLPVILGAVTQFFLMPFCGFL 194
Query: 86 LAISFSLKPVQAIAVLIMGCCPGGTISNIFTFWVDGDMDLSISMTTCSTVAALGMMPLCI 145
L+ +L QA V++ CPGG +F +DGD L+I MT ST+ AL MMP+
Sbjct: 195 LSQIVALPEAQAFGVVMTCTCPGGGGGYLFALLLDGDFTLAILMTCTSTLLALIMMPVNS 254
Query: 146 YLYTWSWSLQQNLTIPYQNIGITLVCLTIPVAFGVYVNYRWPKQSKIILKIGAVVGGVLL 205
Y+Y+ L IP I TL+ + +PV+ G+ + +R P+++ + +I + +L+
Sbjct: 255 YIYSRILGLSGTFHIPVSKIVSTLLFILVPVSIGIVIKHRIPEKASFLERIIRPLSFILM 314
Query: 206 LV----VAVAGVVLAKGSWNSDITLLTISFIFPLIGHVTGFLLALFTHQSWQRCRTISLE 261
V G+V K ++ ++ + + P +G + G+ A C+T+++E
Sbjct: 315 FVGIYLTFTVGLVFLK---TDNLEVILLGLLVPALGLLFGYSFAKVCTLPLPVCKTVAIE 371
Query: 262 TGAQNIQMCITMLQLSFTAEHLVQMLSFPLAYGLFQLIDGFLIVAAYQTYKR 313
+G N + + ++QLSF P + + LI+ Y+ KR
Sbjct: 372 SGMLNSFLALAVIQLSFPQSKANLASVAPFTVAMCSGCEMLLIILVYKAKKR 423
>gi|116256358 secretory carrier membrane protein 1 [Homo sapiens]
Length = 338
Score = 34.3 bits (77), Expect = 0.19
Identities = 24/83 (28%), Positives = 40/83 (48%), Gaps = 3/83 (3%)
Query: 218 GSWNSDITLLTISFIFPLIGHVTGFLLALFTHQSWQRCRTISLETGA-QNIQMCITMLQL 276
G++ SD + F F I +L +W C IS TG QNI + I M+ +
Sbjct: 208 GAFRSDSSFRFFVFFFVYICQFAVHVLQAAGFHNWGNCGWISSLTGLNQNIPVGIMMIII 267
Query: 277 S--FTAEHLVQMLSFPLAYGLFQ 297
+ FTA ++ ++ F +GL++
Sbjct: 268 AALFTASAVISLVMFKKVHGLYR 290
>gi|110347437 latent transforming growth factor beta binding protein
4 isoform c [Homo sapiens]
Length = 1557
Score = 29.6 bits (65), Expect = 4.6
Identities = 18/56 (32%), Positives = 23/56 (41%), Gaps = 13/56 (23%)
Query: 315 LKNKHGKKNSGCTEVCHTRKSTSSRETNAFLEVNEEGAITPGPPG------PMDCH 364
L+ HG S CT C R +TS ++ G PG PG P+ CH
Sbjct: 43 LRCVHGPTGSRCTPTCAPRNATS-------VDSGAPGGAAPGGPGFRAFLCPLICH 91
>gi|50080197 olfactory receptor, family 13, subfamily C, member 9
[Homo sapiens]
Length = 318
Score = 28.9 bits (63), Expect = 7.9
Identities = 27/93 (29%), Positives = 38/93 (40%), Gaps = 11/93 (11%)
Query: 23 GLEVHGNLELVFTVVSTVMMGLLMFSLGCSVEIRKLWSHIRRPWGIAVGLLCQFG----- 77
G VH LEL+F V+ +M +++ G + I L H+ P +G L
Sbjct: 16 GHSVHPRLELLFFVLIFIMYVVILLGNGTLILISILDPHLHTPMYFFLGNLSFLDICYTT 75
Query: 78 ------LMPFTAYLLAISFSLKPVQAIAVLIMG 104
L+ F + ISFS VQ L MG
Sbjct: 76 TSIPSTLVSFLSERKTISFSGCAVQMFLGLAMG 108
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.138 0.436
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,101,067
Number of Sequences: 37866
Number of extensions: 582731
Number of successful extensions: 2519
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 2503
Number of HSP's gapped (non-prelim): 11
length of query: 377
length of database: 18,247,518
effective HSP length: 104
effective length of query: 273
effective length of database: 14,309,454
effective search space: 3906480942
effective search space used: 3906480942
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.