Search of human proteins with 34485722

Search of human proteins with 34485722

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|34485722 karyopherin alpha 3 [Homo sapiens]
         (521 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|34485722 karyopherin alpha 3 [Homo sapiens]                       1035   0.0  
gi|4504901 karyopherin alpha 4 [Homo sapiens]                         905   0.0  
gi|4504897 karyopherin alpha 2 [Homo sapiens]                         499   e-141
gi|39812229 karyopherin alpha 5 [Homo sapiens]                        474   e-133
gi|6912478 karyopherin alpha 6 [Homo sapiens]                         467   e-131
gi|222144293 karyopherin alpha 1 [Homo sapiens]                       462   e-130
gi|224589129 karyopherin 7 [Homo sapiens]                             427   e-120
gi|6912678 sperm associated antigen 6 isoform 1 [Homo sapiens]         72   1e-12
gi|27262641 sperm associated antigen 6 isoform 2 [Homo sapiens]        72   1e-12
gi|189409124 armadillo repeat containing 3 [Homo sapiens]              50   7e-06
gi|94536840 transmembrane and coiled-coil domains 6 [Homo sapiens]     50   7e-06
gi|91206450 ankyrin and armadillo repeat containing [Homo sapiens]     48   2e-05
gi|32526896 armadillo repeat containing 8 isoform 2 [Homo sapiens]     47   6e-05
gi|10863903 thyroid hormone receptor interactor 12 [Homo sapiens]      40   0.007
gi|28875784 armadillo repeat containing 5 isoform b [Homo sapiens]     37   0.057
gi|157426856 armadillo repeat containing 5 isoform a [Homo sapiens]    37   0.057
gi|148227672 catenin (cadherin-associated protein), beta 1, 88kD...    36   0.075
gi|148233338 catenin (cadherin-associated protein), beta 1, 88kD...    36   0.075
gi|4503131 catenin (cadherin-associated protein), beta 1, 88kDa ...    36   0.075
gi|146231975 catenin, delta 1 isoform 3A [Homo sapiens]                36   0.075
gi|146231948 catenin, delta 1 isoform 3A [Homo sapiens]                36   0.075
gi|146231994 catenin, delta 1 isoform 3A [Homo sapiens]                36   0.075
gi|146231977 catenin, delta 1 isoform 3AC [Homo sapiens]               36   0.075
gi|146231946 catenin, delta 1 isoform 3B [Homo sapiens]                36   0.075
gi|146231991 catenin, delta 1 isoform 3AB [Homo sapiens]               36   0.075
gi|146231970 catenin, delta 1 isoform 3ABC [Homo sapiens]              36   0.075
gi|146231942 catenin, delta 1 isoform 1A [Homo sapiens]                36   0.075
gi|146231968 catenin, delta 1 isoform 1A [Homo sapiens]                36   0.075
gi|146231938 catenin, delta 1 isoform 1A [Homo sapiens]                36   0.075
gi|10835010 catenin, delta 1 isoform 1B [Homo sapiens]                 36   0.075

>gi|34485722 karyopherin alpha 3 [Homo sapiens]
          Length = 521

 Score = 1035 bits (2675), Expect = 0.0
 Identities = 521/521 (100%), Positives = 521/521 (100%)

Query: 1   MAENPSLENHRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDS 60
           MAENPSLENHRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDS
Sbjct: 1   MAENPSLENHRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDS 60

Query: 61  DVDADFKAQNVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILV 120
           DVDADFKAQNVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILV
Sbjct: 61  DVDADFKAQNVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILV 120

Query: 121 KCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWA 180
           KCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWA
Sbjct: 121 KCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWA 180

Query: 181 LGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETV 240
           LGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETV
Sbjct: 181 LGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETV 240

Query: 241 QEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKV 300
           QEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKV
Sbjct: 241 QEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKV 300

Query: 301 QTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQ 360
           QTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQ
Sbjct: 301 QTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQ 360

Query: 361 VQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCNLL 420
           VQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCNLL
Sbjct: 361 VQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCNLL 420

Query: 421 SVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEVLQQHENEDIYKLAFEI 480
           SVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEVLQQHENEDIYKLAFEI
Sbjct: 421 SVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEVLQQHENEDIYKLAFEI 480

Query: 481 IDQYFSGDDIDEDPCLIPEATQGGTYNFDPTANLQTKEFNF 521
           IDQYFSGDDIDEDPCLIPEATQGGTYNFDPTANLQTKEFNF
Sbjct: 481 IDQYFSGDDIDEDPCLIPEATQGGTYNFDPTANLQTKEFNF 521


>gi|4504901 karyopherin alpha 4 [Homo sapiens]
          Length = 521

 Score =  905 bits (2338), Expect = 0.0
 Identities = 447/521 (85%), Positives = 481/521 (92%)

Query: 1   MAENPSLENHRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDS 60
           MA+N  L+N R+K+FKNKGRD+ETMRR RNEV VELRKNKRDEHLLK+RNVP E+  EDS
Sbjct: 1   MADNEKLDNQRLKNFKNKGRDLETMRRQRNEVVVELRKNKRDEHLLKRRNVPHEDICEDS 60

Query: 61  DVDADFKAQNVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILV 120
           D+D D++ QN +LEAI+QNA+SDN  +QLSAVQAARKLLSSDRNPPIDDLIKSGILPILV
Sbjct: 61  DIDGDYRVQNTSLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILV 120

Query: 121 KCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWA 180
            CLERDDNPSLQFEAAWALTNIASGTS QTQAVVQSNAVPLFLRLL SPHQNVCEQAVWA
Sbjct: 121 HCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWA 180

Query: 181 LGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETV 240
           LGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWV+VNLCR+KDPPPPMET+
Sbjct: 181 LGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETI 240

Query: 241 QEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKV 300
           QEILPALCVLI+HTD+NILVDTVWALSYLTD GNEQIQMVIDSG+VP LVPLLSHQEVKV
Sbjct: 241 QEILPALCVLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKV 300

Query: 301 QTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQ 360
           QTAALRAVGNIVTGTDEQTQVVLNCD LSHFP LL+HPKEKINKEAVWFLSNITAGNQQQ
Sbjct: 301 QTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQ 360

Query: 361 VQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCNLL 420
           VQAVIDA L+PMIIH L KGDFGTQKEAAWAISNLTISGRKDQV YL+QQNVIPPFCNLL
Sbjct: 361 VQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLL 420

Query: 421 SVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEVLQQHENEDIYKLAFEI 480
           +VKD+QVVQVVLDGL NIL MA DEA TI  +IEECGGLEKIE LQ HENEDIYKLA+EI
Sbjct: 421 TVKDAQVVQVVLDGLSNILKMAEDEAETIGNLIEECGGLEKIEQLQNHENEDIYKLAYEI 480

Query: 481 IDQYFSGDDIDEDPCLIPEATQGGTYNFDPTANLQTKEFNF 521
           IDQ+FS DDIDEDP L+PEA QGGT+ F+ +AN+ T+ F F
Sbjct: 481 IDQFFSSDDIDEDPSLVPEAIQGGTFGFNSSANVPTEGFQF 521


>gi|4504897 karyopherin alpha 2 [Homo sapiens]
          Length = 529

 Score =  499 bits (1285), Expect = e-141
 Identities = 259/515 (50%), Positives = 350/515 (67%), Gaps = 11/515 (2%)

Query: 3   ENPSLENHRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDV 62
           EN +    R+  FKNKG+D   MRR R EV VELRK K+D+ +LK+RNV        S +
Sbjct: 5   ENANTPAARLHRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDATSPL 64

Query: 63  DADFKAQ---NVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPIL 119
             +   Q   N +++ I++   S N   QL A QAARKLLS ++ PPID++I++G++P  
Sbjct: 65  QENRNNQGTVNWSVDDIVKGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKF 124

Query: 120 VKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVW 179
           V  L R D   +QFE+AWALTNIASGTS QT+AVV   A+P F+ LL SPH ++ EQAVW
Sbjct: 125 VSFLGRTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVW 184

Query: 180 ALGNIIGDGPQCRDYVISLGVVKPLLSFIS----PSIPITFLRNVTWVIVNLCRNKDPPP 235
           ALGNI GDG   RD VI  G V PLL+ ++     S+   +LRN+TW + NLCRNK+P P
Sbjct: 185 ALGNIAGDGSVFRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNLCRNKNPAP 244

Query: 236 PMETVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSH 295
           P++ V++ILP L  L++H D  +L DT WA+SYLTDG NE+I MV+ +GVVP LV LL  
Sbjct: 245 PIDAVEQILPTLVRLLHHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGA 304

Query: 296 QEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITA 355
            E+ + T ALRA+GNIVTGTDEQTQVV++   L+ FP+LL++PK  I KEA W +SNITA
Sbjct: 305 SELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITA 364

Query: 356 GNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVIPP 415
           G Q Q+Q V++ GL+P ++  L+K DF TQKEA WA++N T  G  +Q+ YLV   +I P
Sbjct: 365 GRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVHCGIIEP 424

Query: 416 FCNLLSVKDSQVVQVVLDGLKNILIMAG--DEASTIAEIIEECGGLEKIEVLQQHENEDI 473
             NLL+ KD++++ V+LD + NI   A    E   ++ +IEECGGL+KIE LQ HENE +
Sbjct: 425 LMNLLTAKDTKIILVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQNHENESV 484

Query: 474 YKLAFEIIDQYFSGDDIDEDPCLIPEATQGGTYNF 508
           YK +  +I++YFS ++ +ED  ++PE T  G Y F
Sbjct: 485 YKASLSLIEKYFSVEE-EEDQNVVPETTSEG-YTF 517


>gi|39812229 karyopherin alpha 5 [Homo sapiens]
          Length = 539

 Score =  474 bits (1219), Expect = e-133
 Identities = 252/517 (48%), Positives = 343/517 (66%), Gaps = 20/517 (3%)

Query: 4   NPSLENHRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNV----PQEESLED 59
           +P  +N+R+KS+KNK  + + MRR R E  ++LRK KR+E L K+RNV      E  LE 
Sbjct: 6   SPGKDNYRMKSYKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVYLPRNDESMLES 65

Query: 60  SDVDADFKA------QNVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLI-K 112
              D D  +      + V    ++Q   S+N   QL+A Q  RKLLS + NPPID +I K
Sbjct: 66  PIQDPDISSTVPIPEEEVVTTDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPIDQVIQK 125

Query: 113 SGILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQN 172
            G++   VK LER++N +LQFEAAWALTNIASGT   T+ V+++ AVP+F++LL S H++
Sbjct: 126 PGVVQRFVKFLERNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHED 185

Query: 173 VCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKD 232
           V EQAVWALGNI GD  +CRD+V++  ++ PLL  ++ S  +T  RN  W + NLCR K+
Sbjct: 186 VQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNLCRGKN 245

Query: 233 PPPPMETVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPL 292
           PPP    V   L  L  L++ +D ++L D  WALSYL+DG N++IQ VIDSGV   LV L
Sbjct: 246 PPPNFSKVSPCLNVLSRLLFSSDPDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRLVEL 305

Query: 293 LSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSN 352
           L H + KV + ALRAVGNIVTG D QTQV+LNC  L    +LLS PKE I KEA W +SN
Sbjct: 306 LMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTVSN 365

Query: 353 ITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNV 412
           ITAGN+ Q+QAVIDA + P++I  L K +F T+KEAAWAI+N T  G  +Q+ YLV    
Sbjct: 366 ITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVALGC 425

Query: 413 IPPFCNLLSVKDSQVVQVVLDGLKNILIMAGDEA-------STIAEIIEECGGLEKIEVL 465
           I P C+LL+V DS++VQV L+GL+NIL +   E+       +    +IEE  GL+KIE L
Sbjct: 426 IKPLCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGIGINPYCALIEEAYGLDKIEFL 485

Query: 466 QQHENEDIYKLAFEIIDQYFSGDDIDEDPCLIPEATQ 502
           Q HEN++IY+ AF++I+ YF  +  ++DP ++P+  +
Sbjct: 486 QSHENQEIYQKAFDLIEHYFGVE--EDDPSIVPQVDE 520


>gi|6912478 karyopherin alpha 6 [Homo sapiens]
          Length = 536

 Score =  467 bits (1202), Expect = e-131
 Identities = 247/514 (48%), Positives = 345/514 (67%), Gaps = 17/514 (3%)

Query: 4   NPSLENHRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVP---QEESLEDS 60
           +P  +N+R+KS+KN   + E MRR R E  ++LRK KR++ L K+RNV    +E ++ DS
Sbjct: 6   SPGKDNYRMKSYKNNALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAAMFDS 65

Query: 61  DVDADFKA----QNVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSG-I 115
            +   + +    ++V    +++   SD+  +QL+  Q  RKLLS + +PPID++I +  +
Sbjct: 66  LLMDSYVSSTTGESVITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRV 125

Query: 116 LPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCE 175
           +   V+ L+R++N +LQFEAAWALTNIASGTS QT+ V+++ AVP+F+ LL S  ++V E
Sbjct: 126 VDRFVEFLKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQE 185

Query: 176 QAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPP 235
           QAVWALGNI GD   CRDYV++  ++ PLL+ ++ S  +T  RN  W + NLCR K+PPP
Sbjct: 186 QAVWALGNIAGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPP 245

Query: 236 PMETVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSH 295
               V   LP L  L++ +D ++L D  WALSYL+DG NE+IQ VIDSGV   LV LL H
Sbjct: 246 EFAKVSPCLPVLSRLLFSSDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMH 305

Query: 296 QEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITA 355
            + KV + ALRAVGNIVTG D QTQV+LNC  L    +LLS PKE I KEA W +SNITA
Sbjct: 306 NDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTISNITA 365

Query: 356 GNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVIPP 415
           GN+ Q+QAVIDA + P++I  L K +F T+KEAAWAI+N T  G  +Q+ YLV    I P
Sbjct: 366 GNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVSLGCIKP 425

Query: 416 FCNLLSVKDSQVVQVVLDGLKNILIM-------AGDEASTIAEIIEECGGLEKIEVLQQH 468
            C+LL+V DS++VQV L+GL+NIL +       +G   +    +IEE  GL+KIE LQ H
Sbjct: 426 LCDLLTVMDSKIVQVALNGLENILRLGEQEGKRSGSGVNPYCGLIEEAYGLDKIEFLQSH 485

Query: 469 ENEDIYKLAFEIIDQYFSGDDIDEDPCLIPEATQ 502
           EN++IY+ AF++I+ YF  +  D+D  L P+  +
Sbjct: 486 ENQEIYQKAFDLIEHYFGVE--DDDSSLAPQVDE 517


>gi|222144293 karyopherin alpha 1 [Homo sapiens]
          Length = 538

 Score =  462 bits (1189), Expect = e-130
 Identities = 249/515 (48%), Positives = 333/515 (64%), Gaps = 22/515 (4%)

Query: 5   PSLENHRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDA 64
           P  EN R+KS+KNK  + + MRR R E  ++LRK KR+E L K+RNV   E   + +V +
Sbjct: 4   PGKENFRLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMS 63

Query: 65  D---FKAQNVTLEA---------ILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIK 112
           D    +AQ   +E          +++   S +P  QLSA Q  RKLLS + NPPID++I 
Sbjct: 64  DGGFHEAQISNMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVIS 123

Query: 113 S-GILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQ 171
           + G++   V+ L+R +N +LQFE+AW LTNIASG S QT+ V+Q+ AVP+F+ LL S  +
Sbjct: 124 TPGVVARFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFE 183

Query: 172 NVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNK 231
           +V EQAVWALGNI GD   CRDYV+   ++ PLL   S    +T  RN  W + NLCR K
Sbjct: 184 DVQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGK 243

Query: 232 DPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVP 291
            PPP    V   L  L  L++ +D ++L D  WALSYL+DG N++IQ VID+GV   LV 
Sbjct: 244 SPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVE 303

Query: 292 LLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLS 351
           LL H + KV + ALRAVGNIVTG D QTQV+LNC  L    +LLS PKE I KEA W +S
Sbjct: 304 LLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTIS 363

Query: 352 NITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQN 411
           NITAGN+ Q+Q VIDA + P +I  L   +F T+KEAAWAI+N T  G  +Q++YLV+  
Sbjct: 364 NITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVELG 423

Query: 412 VIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGDEA-------STIAEIIEECGGLEKIEV 464
            I P C+LL+V DS++VQV L+GL+NIL +   EA       +    +IEE  GL+KIE 
Sbjct: 424 CIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEAKRNGTGINPYCALIEEAYGLDKIEF 483

Query: 465 LQQHENEDIYKLAFEIIDQYFSGDDIDEDPCLIPE 499
           LQ HEN++IY+ AF++I+ YF  +  DED  + P+
Sbjct: 484 LQSHENQEIYQKAFDLIEHYFGTE--DEDSSIAPQ 516


>gi|224589129 karyopherin 7 [Homo sapiens]
          Length = 516

 Score =  427 bits (1099), Expect = e-120
 Identities = 227/499 (45%), Positives = 322/499 (64%), Gaps = 5/499 (1%)

Query: 5   PSLE--NHRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDV 62
           P+L+    R + FK +G+DV   R+ R  V++ELRK K+DE  LK+RN+        S+ 
Sbjct: 2   PTLDAPEERRRKFKYRGKDVSLRRQQRMAVSLELRKAKKDEQTLKRRNITSFCPDTPSEK 61

Query: 63  DADFKAQNVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKC 122
            A   A ++TL  I++   S +PV+   A Q ARK+LS ++NPP+  +I++G++P +V+ 
Sbjct: 62  TAKGVAVSLTLGEIIKGVNSSDPVLCFQATQTARKMLSQEKNPPLKLVIEAGLIPRMVEF 121

Query: 123 LERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALG 182
           L+    P LQFEAAWALTNIASGTS QT+AVV+  A+   + LL S +  VCEQAVWALG
Sbjct: 122 LKSSLYPCLQFEAAWALTNIASGTSEQTRAVVEGGAIQPLIELLSSSNVAVCEQAVWALG 181

Query: 183 NIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQE 242
           NI GDGP+ RD VI+   +  LL+ ISP++PITFLRN+TW + NLCRNK+P P    V++
Sbjct: 182 NIAGDGPEFRDNVITSNAIPHLLALISPTLPITFLRNITWTLSNLCRNKNPYPCDTAVKQ 241

Query: 243 ILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQT 302
           ILPAL  L+ H D  +L D  WALSYLTDG N++I  V+++GV+P LV L++  E+ V T
Sbjct: 242 ILPALLHLLQHQDSEVLSDACWALSYLTDGSNKRIGQVVNTGVLPRLVVLMTSSELNVLT 301

Query: 303 AALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQVQ 362
            +LR VGNIVTGTDEQTQ+ ++  +L+  P LL H K  I KEA W LSN+ AG    +Q
Sbjct: 302 PSLRTVGNIVTGTDEQTQMAIDAGMLNVLPQLLQHNKPSIQKEAAWALSNVAAGPCHHIQ 361

Query: 363 AVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCNLLSV 422
            ++   ++P ++  L  G+F  QKEA W ++N       DQ+  LV   V+ P  NLL+ 
Sbjct: 362 QLLAYDVLPPLVALLKNGEFKVQKEAVWMVANFATGATMDQLIQLVHSGVLEPLVNLLTA 421

Query: 423 KDSQVVQVVLDGLKNILIMA--GDEASTIAEIIEECGGLEKIEVLQQHENEDIYKLAFEI 480
            D ++V ++LD +  IL  A    E   +  +IEE GG+++IE LQ HEN  I + A  I
Sbjct: 422 PDVKIVLIILDVISCILQAAEKRSEKENLCLLIEELGGIDRIEALQLHENRQIGQSALNI 481

Query: 481 IDQYFSGDDIDEDPCLIPE 499
           I+++F G++ DE   L+ +
Sbjct: 482 IEKHF-GEEEDESQTLLSQ 499


>gi|6912678 sperm associated antigen 6 isoform 1 [Homo sapiens]
          Length = 509

 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 63/304 (20%), Positives = 124/304 (40%), Gaps = 46/304 (15%)

Query: 92  VQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQ 151
           VQ   +L +  +N  I+ L  +G++ +L + L  D  P++Q  AA AL  +A+      +
Sbjct: 21  VQMVAELATRPQN--IETLQNAGVMSLL-RTLLLDVVPTIQQTAALALGRLANYNDDLAE 77

Query: 152 AVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPS 211
           AVV+ + +P  +  L   ++   + A + L  +    PQ    ++  G            
Sbjct: 78  AVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGA----------- 126

Query: 212 IPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYLTD 271
                                           L  L + +   D  +     WAL Y+  
Sbjct: 127 --------------------------------LDTLVICLEDFDPGVKEAAAWALRYIAR 154

Query: 272 GGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHF 331
              E  Q V+D+G VP LV  +   E+ ++  A  A+ +I   + E  Q V++   ++H 
Sbjct: 155 HNAELSQAVVDAGAVPLLVLCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHL 214

Query: 332 PNLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWA 391
             ++ +P  K+  + +  LS ++  +    + V++A + P+++  L   D   +K A+  
Sbjct: 215 AQMILNPDAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTL 274

Query: 392 ISNL 395
           I  +
Sbjct: 275 IREI 278



 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 59/267 (22%), Positives = 111/267 (41%), Gaps = 5/267 (1%)

Query: 110 LIKSGILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSP 169
           ++  G L  LV CLE D +P ++  AAWAL  IA   +  +QAVV + AVPL +  ++ P
Sbjct: 121 IVDCGALDTLVICLE-DFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEP 179

Query: 170 HQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFI-SPSIPITFLRNVTWVIVNLC 228
              +   A  AL +I    P+    V+  G V  L   I +P   +     +   +  + 
Sbjct: 180 EIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLK--HQILSALSQVS 237

Query: 229 RNKDPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPF 288
           ++      M    EI P +   +   D  +  +    +  +     E  Q+V+++G V  
Sbjct: 238 KHSVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAA 297

Query: 289 LVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLS-HPKEKINKEAV 347
           ++  +   +   +   +  +G +   ++     V+    +      LS  P++ I   A 
Sbjct: 298 VIDCIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAA 357

Query: 348 WFLSNITAGNQQQVQAVIDAGLIPMII 374
           W L  I     +  +AV     +P+++
Sbjct: 358 WALGQIGRHTPEHARAVAVTNTLPVLL 384



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 1/59 (1%)

Query: 110 LIKSGILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRS 168
           +I  G+ P L  CL  +    ++  AAWAL  I   T    +AV  +N +P+ L L  S
Sbjct: 332 IISKGV-PQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYMS 389


>gi|27262641 sperm associated antigen 6 isoform 2 [Homo sapiens]
          Length = 458

 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 63/304 (20%), Positives = 124/304 (40%), Gaps = 46/304 (15%)

Query: 92  VQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQ 151
           VQ   +L +  +N  I+ L  +G++ +L + L  D  P++Q  AA AL  +A+      +
Sbjct: 21  VQMVAELATRPQN--IETLQNAGVMSLL-RTLLLDVVPTIQQTAALALGRLANYNDDLAE 77

Query: 152 AVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPS 211
           AVV+ + +P  +  L   ++   + A + L  +    PQ    ++  G            
Sbjct: 78  AVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGA----------- 126

Query: 212 IPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYLTD 271
                                           L  L + +   D  +     WAL Y+  
Sbjct: 127 --------------------------------LDTLVICLEDFDPGVKEAAAWALRYIAR 154

Query: 272 GGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHF 331
              E  Q V+D+G VP LV  +   E+ ++  A  A+ +I   + E  Q V++   ++H 
Sbjct: 155 HNAELSQAVVDAGAVPLLVLCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHL 214

Query: 332 PNLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWA 391
             ++ +P  K+  + +  LS ++  +    + V++A + P+++  L   D   +K A+  
Sbjct: 215 AQMILNPDAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTL 274

Query: 392 ISNL 395
           I  +
Sbjct: 275 IREI 278



 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 59/267 (22%), Positives = 111/267 (41%), Gaps = 5/267 (1%)

Query: 110 LIKSGILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSP 169
           ++  G L  LV CLE D +P ++  AAWAL  IA   +  +QAVV + AVPL +  ++ P
Sbjct: 121 IVDCGALDTLVICLE-DFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEP 179

Query: 170 HQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFI-SPSIPITFLRNVTWVIVNLC 228
              +   A  AL +I    P+    V+  G V  L   I +P   +     +   +  + 
Sbjct: 180 EIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLK--HQILSALSQVS 237

Query: 229 RNKDPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPF 288
           ++      M    EI P +   +   D  +  +    +  +     E  Q+V+++G V  
Sbjct: 238 KHSVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAA 297

Query: 289 LVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLS-HPKEKINKEAV 347
           ++  +   +   +   +  +G +   ++     V+    +      LS  P++ I   A 
Sbjct: 298 VIDCIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAA 357

Query: 348 WFLSNITAGNQQQVQAVIDAGLIPMII 374
           W L  I     +  +AV     +P+++
Sbjct: 358 WALGQIGRHTPEHARAVAVTNTLPVLL 384



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 1/59 (1%)

Query: 110 LIKSGILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRS 168
           +I  G+ P L  CL  +    ++  AAWAL  I   T    +AV  +N +P+ L L  S
Sbjct: 332 IISKGV-PQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYMS 389


>gi|189409124 armadillo repeat containing 3 [Homo sapiens]
          Length = 872

 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 63/258 (24%), Positives = 118/258 (45%), Gaps = 18/258 (6%)

Query: 232 DPPP-----PMETVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVV 286
           +PPP     P+    +    + +++   +  IL     A+      G E    +++ G V
Sbjct: 10  EPPPKDVFDPLMIESKKAATVVLMLNSPEEEILAKACEAIYKFALKGEENKTTLLELGAV 69

Query: 287 PFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKE- 345
             L  LL+H++  V+  A    G I+   ++  +++   DV++     L+  +E +  E 
Sbjct: 70  EPLTKLLTHEDKIVRRNATMIFG-ILASNNDVKKLLRELDVMNSVIAQLAPEEEVVIHEF 128

Query: 346 AVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVE 405
           A   L+N++A    +VQ     GL P +I  L+  D   +K +   I NL    +  Q  
Sbjct: 129 ASLCLANMSAEYTSKVQIFEHGGLEP-LIRLLSSPDPDVKKNSMECIYNLV---QDFQCR 184

Query: 406 YLVQQ-NVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEK-IE 463
             +Q+ N IPP  +LL    S+   + L  LK + ++A D+ S    ++ +  GL+  I+
Sbjct: 185 AKLQELNAIPPILDLLK---SEYPVIQLLALKTLGVIANDKES--RTMLRDNQGLDHLIK 239

Query: 464 VLQQHENEDIYKLAFEII 481
           +L+  E  D++  A  +I
Sbjct: 240 ILETKELNDLHIEALAVI 257



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 85/405 (20%), Positives = 163/405 (40%), Gaps = 43/405 (10%)

Query: 73  LEAILQNATSDNPVVQLSAV----------QAARKLLSSDRNPPIDDLIKSGILPILVKC 122
           LE +++  +S +P V+ +++          Q   KL   +  PPI DL+KS         
Sbjct: 152 LEPLIRLLSSPDPDVKKNSMECIYNLVQDFQCRAKLQELNAIPPILDLLKS--------- 202

Query: 123 LERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCE-QAVWAL 181
               + P +Q  A   L  IA+   ++T  +  +  +   +++L +   N    +A+  +
Sbjct: 203 ----EYPVIQLLALKTLGVIANDKESRTM-LRDNQGLDHLIKILETKELNDLHIEALAVI 257

Query: 182 GNIIGDGPQCRDYVISL---GVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPME 238
            N + D     D ++ +   G +K LLSF   S      +N    I     + +      
Sbjct: 258 ANCLED----MDTMVQIQQTGGLKKLLSFAENSTIPDIQKNAAKAITKAAYDPENRKLFH 313

Query: 239 TVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEV 298
             QE+   L  L+   +    +    A+S + +  N   +   ++  +P L+ LL     
Sbjct: 314 E-QEVEKCLVALLGSENDGTKIAASQAISAMCE--NSGSKDFFNNQGIPQLIQLLKSDNE 370

Query: 299 KVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQ 358
           +V+ AA  A+ N+ T            D +    NLLS  ++     A   L+N+     
Sbjct: 371 EVREAAALALANLTTCNPANANAAAEADGIDPLINLLSSKRDGAIANAATVLTNMAMQEP 430

Query: 359 QQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCN 418
            ++  + +  ++  II  L   +   Q +AA A++  T    + + E L     + P   
Sbjct: 431 LRLN-IQNHDIMHAIISPLRSANTVVQSKAALAVT-ATACDVEARTE-LRNSGGLEPLVE 487

Query: 419 LLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIE 463
           LL  K+ +V +        +++ AGDE +  A  +   G L+ +E
Sbjct: 488 LLRSKNDEVRK---HASWAVMVCAGDELT--ANELCRLGALDILE 527



 Score = 37.7 bits (86), Expect = 0.026
 Identities = 32/160 (20%), Positives = 69/160 (43%), Gaps = 2/160 (1%)

Query: 153 VVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPSI 212
           +++S      + +L SP + +  +A  A+      G + +  ++ LG V+PL   ++   
Sbjct: 21  MIESKKAATVVLMLNSPEEEILAKACEAIYKFALKGEENKTTLLELGAVEPLTKLLTHED 80

Query: 213 PITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYLTDG 272
            I   RN T +   L  N D    +  +  +   +  L    ++ I       L+ ++  
Sbjct: 81  KIV-RRNATMIFGILASNNDVKKLLRELDVMNSVIAQLAPEEEVVIHEFASLCLANMSAE 139

Query: 273 GNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIV 312
              ++Q+    G+ P L+ LLS  +  V+  ++  + N+V
Sbjct: 140 YTSKVQIFEHGGLEP-LIRLLSSPDPDVKKNSMECIYNLV 178


>gi|94536840 transmembrane and coiled-coil domains 6 [Homo sapiens]
          Length = 493

 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 101/486 (20%), Positives = 190/486 (39%), Gaps = 61/486 (12%)

Query: 22  VETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQNVTLEAILQNAT 81
           VE +RR R E    LRK +R++ L+ KR +  +   E  +           ++  L+ A 
Sbjct: 16  VEELRRRRREREAALRKARREQQLVSKRLLRNDAPEEAGEGCVAAILGETEVQQFLRQAQ 75

Query: 82  --SDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWAL 139
             ++    + + V   R L   +       L   G +  LV  L   +   LQ EAA  L
Sbjct: 76  RGTEEKEREGALVSLRRGLQHPETQQTFIRL--EGSMRTLVGLLT-SNQALLQLEAARCL 132

Query: 140 TNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQCRDYVISLG 199
             + S +   T A     A    L  L S   +  E  ++ LGN+I +    R  ++  G
Sbjct: 133 HEL-SHSEQSTVAEACLPATSYLLTYLSSHSSDFIELCLYTLGNLIVESEAVRRQLLPQG 191

Query: 200 VVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPAL--CVLIYH---- 253
           +V P L+    S  +  L  + + +  L + ++ P      ++I+P++    L  H    
Sbjct: 192 IV-PALAACIQSPHVAVLEALGYALSQLLQAEEAP------EKIIPSILASTLPQHMLQM 244

Query: 254 ------TDINILVDTVWALSYL--TDGGNE--------------------QIQMVIDSGV 285
                  +  + V+  W L Y+  +   N                      +Q   D+G+
Sbjct: 245 LQPGPKLNPGVAVEFAWCLHYIICSQVSNPLLIGHGALSTLGLLLLDLAGAVQKTEDAGL 304

Query: 286 VPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKE 345
                P+L      +  AA+  VG  +   DE  +VV    +L  F       +  +  E
Sbjct: 305 ELLACPVLRCLSNLLTEAAVETVGGQMQLRDE--RVVAALFILLQF---FFQKQPSLLPE 359

Query: 346 AVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVE 405
            +W L+N+TA +     +++   LI  ++  L   +          + N+   G     +
Sbjct: 360 GLWLLNNLTANSPSFCTSLLSLDLIEPLLQLLPVSNV-VSVMVLTVLCNVAEKG-PAYCQ 417

Query: 406 YLVQQNVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEVL 465
            L    ++P   + L+  D++VV   L+ L ++L +   EA  +   +++ G    ++ L
Sbjct: 418 RLWPGPLLPALLHTLAFSDTEVVGQSLE-LLHLLFLYQPEA--VQVFLQQSG----LQAL 470

Query: 466 QQHENE 471
           ++H+ E
Sbjct: 471 ERHQEE 476


>gi|91206450 ankyrin and armadillo repeat containing [Homo sapiens]
          Length = 1363

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 38/152 (25%), Positives = 73/152 (48%), Gaps = 4/152 (2%)

Query: 289 LVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVW 348
           LV +L  +  K +  A+ ++  I    D+  + +L+   +    NLL   K K+  + V 
Sbjct: 634 LVEMLQCESYKRRMMAVMSLEVICLANDQYWRCILDAGTIPALINLLKSSKIKLQCKTVG 693

Query: 349 FLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLV 408
            LSNI+  ++  V A+++AG IP +I+ L   +       A  + ++     KD    + 
Sbjct: 694 LLSNIST-HKSAVHALVEAGGIPSLINLLVCDEPEVHSRCAVILYDIAQCENKD---VIA 749

Query: 409 QQNVIPPFCNLLSVKDSQVVQVVLDGLKNILI 440
           + N IP   NLL++    V+  V++ ++ + I
Sbjct: 750 KYNGIPSLINLLNLNIENVLVNVMNCIRVLCI 781



 Score = 34.7 bits (78), Expect = 0.22
 Identities = 46/277 (16%), Positives = 102/277 (36%), Gaps = 9/277 (3%)

Query: 135 AAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQCRDY 194
           A  +L  I        + ++ +  +P  + LL+S    +  + V  L NI          
Sbjct: 649 AVMSLEVICLANDQYWRCILDAGTIPALINLLKSSKIKLQCKTVGLLSNI-STHKSAVHA 707

Query: 195 VISLGVVKPLLSFISPSIPITFLR-NVTWVIVNLCRNKDPPPPMETVQEILPALCVLIYH 253
           ++  G +  L++ +    P    R  V    +  C NKD       +    P+L  L+  
Sbjct: 708 LVEAGGIPSLINLLVCDEPEVHSRCAVILYDIAQCENKDVIAKYNGI----PSLINLLNL 763

Query: 254 TDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVT 313
              N+LV+ +  +  L  G     + V +   +P+L+  LS     ++  +  A+  +  
Sbjct: 764 NIENVLVNVMNCIRVLCIGNENNQRAVREHKGLPYLIRFLSSDSDVLKAVSSAAIAEVGR 823

Query: 314 GTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMI 373
              E    +     +     L    +  +  +    + ++ + N    +A ++  L   +
Sbjct: 824 DNKEIQDAIAMEGAIPPLVALFKGKQISVQMKGAMAVESLASHNALIQKAFLEKSLTKYL 883

Query: 374 IHQLAKGDFGTQKEAA---WAISNLTISGRKDQVEYL 407
           +  L       +++ A   WA++  T+  +K   E +
Sbjct: 884 LKLLKAFQIDVKEQGAVALWALAGQTLKQQKYMAEQI 920


>gi|32526896 armadillo repeat containing 8 isoform 2 [Homo sapiens]
          Length = 659

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 52/243 (21%), Positives = 112/243 (46%), Gaps = 17/243 (6%)

Query: 149 QTQAVVQSNAV--PLFLRLLRSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLS 206
           Q +   Q +AV  PL +++L++    +   A   L N++ +    ++ ++  G V+ L  
Sbjct: 403 QLRTSFQDHAVWKPL-MKVLQNAPDEILVVASSMLCNLLLEFSPSKEPILESGAVELLCG 461

Query: 207 FISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEI-LPALCVLIYHTDINILVDTVWA 265
                 P   +  + W ++N+    +     + ++ +    L  L+  +D+N+L+ T+  
Sbjct: 462 LTQSENPALRVNGI-WALMNMAFQAEQKIKADILRSLSTEQLFRLLSDSDLNVLMKTLGL 520

Query: 266 LSYL--TDGGNEQIQMVIDSGVVPFLVPLLSHQ---EVKVQTAALRAVGNIVTGTDEQTQ 320
           L  L  T    ++I       ++  +  +L  +   EVK QT  + A  NI  GT  +  
Sbjct: 521 LRNLLSTRPHIDKIMSTHGKQIMQAVTLILEGEHNIEVKEQTLCILA--NIADGTTAKDL 578

Query: 321 VVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNI----TAGNQQQVQAVIDAGLIPMIIHQ 376
           ++ N D+L      + H   K+   A++ +SN+      G+Q++   + D G++  I+H+
Sbjct: 579 IMTNDDILQKIKYYMGHSHVKLQLAAMFCISNLIWNEEEGSQERQDKLRDMGIVD-ILHK 637

Query: 377 LAK 379
           L++
Sbjct: 638 LSQ 640



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 47/224 (20%), Positives = 96/224 (42%), Gaps = 12/224 (5%)

Query: 73  LEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQ 132
           L  +LQNA  +  VV  S +       S  + P    +++SG + +L   L + +NP+L+
Sbjct: 417 LMKVLQNAPDEILVVASSMLCNLLLEFSPSKEP----ILESGAVELLCG-LTQSENPALR 471

Query: 133 FEAAWALTNIASGTSAQTQA-VVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQC 191
               WAL N+A     + +A +++S +     RLL     NV  + +  L N++   P  
Sbjct: 472 VNGIWALMNMAFQAEQKIKADILRSLSTEQLFRLLSDSDLNVLMKTLGLLRNLLSTRPHI 531

Query: 192 RDYVISLG--VVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCV 249
              + + G  +++ +   +     I        ++ N+         + T  +IL  +  
Sbjct: 532 DKIMSTHGKQIMQAVTLILEGEHNIEVKEQTLCILANIADGTTAKDLIMTNDDILQKIKY 591

Query: 250 LIYHTDINILVDTVWALSYL----TDGGNEQIQMVIDSGVVPFL 289
            + H+ + + +  ++ +S L     +G  E+   + D G+V  L
Sbjct: 592 YMGHSHVKLQLAAMFCISNLIWNEEEGSQERQDKLRDMGIVDIL 635



 Score = 33.1 bits (74), Expect = 0.63
 Identities = 27/114 (23%), Positives = 53/114 (46%), Gaps = 3/114 (2%)

Query: 272 GGNEQIQMVIDSGVVPFLVPLLSHQ--EVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLS 329
           G N+Q   +I  G VP L+ LL  +    +++T     +G++  GT+   + +L+C ++ 
Sbjct: 35  GNNKQKANLIVLGAVPRLLYLLQQETSSTELKTECAVVLGSLAMGTENNVKSLLDCHIIP 94

Query: 330 HFPNLLSHPKEKINKEAVWFLSNI-TAGNQQQVQAVIDAGLIPMIIHQLAKGDF 382
                L  P  K  +  +  L  I T+    +     DA +IP ++  L++  +
Sbjct: 95  ALLQGLLSPDLKFIEACLRCLRTIFTSPVTPEELLYTDATVIPHLMALLSRSRY 148



 Score = 29.6 bits (65), Expect = 7.0
 Identities = 30/140 (21%), Positives = 65/140 (46%), Gaps = 9/140 (6%)

Query: 69  QNVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSG---ILPILVKCLER 125
           ++++ E + +  +  +  V +  +   R LLS+   P ID ++ +    I+  +   LE 
Sbjct: 495 RSLSTEQLFRLLSDSDLNVLMKTLGLLRNLLST--RPHIDKIMSTHGKQIMQAVTLILEG 552

Query: 126 DDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNII 185
           + N  ++ +    L NIA GT+A+   +   + +      +   H  +   A++ + N+I
Sbjct: 553 EHNIEVKEQTLCILANIADGTTAKDLIMTNDDILQKIKYYMGHSHVKLQLAAMFCISNLI 612

Query: 186 ---GDGPQCR-DYVISLGVV 201
               +G Q R D +  +G+V
Sbjct: 613 WNEEEGSQERQDKLRDMGIV 632


>gi|10863903 thyroid hormone receptor interactor 12 [Homo sapiens]
          Length = 1992

 Score = 39.7 bits (91), Expect = 0.007
 Identities = 56/260 (21%), Positives = 102/260 (39%), Gaps = 17/260 (6%)

Query: 74  EAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQF 133
           + +LQ   + +   QL AV    +LL       +       ++P L+  L+ + N  +  
Sbjct: 440 QQLLQGLQASDESQQLQAVIEMCQLLVMGNEETLGGFPVKSVVPALITLLQMEHNFDIMN 499

Query: 134 EAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPH-QNVCEQAVWALGNIIGDGPQCR 192
            A  ALT +       +  VV  +A+P+FL  L+     +V EQA+ AL  +     +  
Sbjct: 500 HACRALTYMMEALPRSSAVVV--DAIPVFLEKLQVIQCIDVAEQALTALEML---SRRHS 554

Query: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIY 252
             ++  G +   L ++     I   RN   +  N C++   P     V + LP L   + 
Sbjct: 555 KAILQAGGLADCLLYLE-FFSINAQRNALAIAANCCQS-ITPDEFHFVADSLPLLTQRLT 612

Query: 253 HTDINILVDTVWALSYLTDGGNEQ---IQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVG 309
           H D   +  T    + L D    +   +Q V    +      L + Q++ V T  + + G
Sbjct: 613 HQDKKSVESTCLCFARLVDNFQHEENLLQQVASKDL------LTNVQQLLVVTPPILSSG 666

Query: 310 NIVTGTDEQTQVVLNCDVLS 329
             +      + +  NC  L+
Sbjct: 667 MFIMVVRMFSLMCSNCPTLA 686


>gi|28875784 armadillo repeat containing 5 isoform b [Homo sapiens]
          Length = 725

 Score = 36.6 bits (83), Expect = 0.057
 Identities = 29/98 (29%), Positives = 49/98 (50%), Gaps = 6/98 (6%)

Query: 114 GILPI--LVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQ 171
           GILP+  +++C++ D   S+Q   A AL N+A    +    +  + AVPL +  L +   
Sbjct: 154 GILPLVTILQCMKTD---SIQNRTARALGNLAMEPESCGD-IHCAGAVPLLVESLTACQD 209

Query: 172 NVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFIS 209
           + C Q+V      + D PQ R  +   G V+PL   ++
Sbjct: 210 SQCLQSVVRALRNLADSPQHRLALAQQGAVRPLAELLA 247



 Score = 33.1 bits (74), Expect = 0.63
 Identities = 38/185 (20%), Positives = 67/185 (36%), Gaps = 9/185 (4%)

Query: 191 CRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVL 250
           CR  V  LG + PL++ +      +        + NL    +    +     +   +  L
Sbjct: 145 CRTEVRRLGGILPLVTILQCMKTDSIQNRTARALGNLAMEPESCGDIHCAGAVPLLVESL 204

Query: 251 IYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGN 310
               D   L   V AL  L D    ++ +     V P    L +  +  +  A +RA+  
Sbjct: 205 TACQDSQCLQSVVRALRNLADSPQHRLALAQQGAVRPLAELLATAPDAALTLALVRALLE 264

Query: 311 IVTGTDEQTQVVLNCDV-LSHFPNLLSHPKEKINKEAVWFLSNITA--------GNQQQV 361
           +  G        L+    L    +L SHPK  + +  +  L+N+ A        GN   V
Sbjct: 265 LSRGCSRACAEQLSLGGGLGPLVSLASHPKRAVREGTILILANLCAQGLIRPALGNAGGV 324

Query: 362 QAVID 366
           + ++D
Sbjct: 325 EVLVD 329


>gi|157426856 armadillo repeat containing 5 isoform a [Homo sapiens]
          Length = 935

 Score = 36.6 bits (83), Expect = 0.057
 Identities = 29/98 (29%), Positives = 49/98 (50%), Gaps = 6/98 (6%)

Query: 114 GILPI--LVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQ 171
           GILP+  +++C++ D   S+Q   A AL N+A    +    +  + AVPL +  L +   
Sbjct: 154 GILPLVTILQCMKTD---SIQNRTARALGNLAMEPESCGD-IHCAGAVPLLVESLTACQD 209

Query: 172 NVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFIS 209
           + C Q+V      + D PQ R  +   G V+PL   ++
Sbjct: 210 SQCLQSVVRALRNLADSPQHRLALAQQGAVRPLAELLA 247



 Score = 33.1 bits (74), Expect = 0.63
 Identities = 38/185 (20%), Positives = 67/185 (36%), Gaps = 9/185 (4%)

Query: 191 CRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVL 250
           CR  V  LG + PL++ +      +        + NL    +    +     +   +  L
Sbjct: 145 CRTEVRRLGGILPLVTILQCMKTDSIQNRTARALGNLAMEPESCGDIHCAGAVPLLVESL 204

Query: 251 IYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGN 310
               D   L   V AL  L D    ++ +     V P    L +  +  +  A +RA+  
Sbjct: 205 TACQDSQCLQSVVRALRNLADSPQHRLALAQQGAVRPLAELLATAPDAALTLALVRALLE 264

Query: 311 IVTGTDEQTQVVLNCDV-LSHFPNLLSHPKEKINKEAVWFLSNITA--------GNQQQV 361
           +  G        L+    L    +L SHPK  + +  +  L+N+ A        GN   V
Sbjct: 265 LSRGCSRACAEQLSLGGGLGPLVSLASHPKRAVREGTILILANLCAQGLIRPALGNAGGV 324

Query: 362 QAVID 366
           + ++D
Sbjct: 325 EVLVD 329


>gi|148227672 catenin (cadherin-associated protein), beta 1, 88kDa
           [Homo sapiens]
          Length = 781

 Score = 36.2 bits (82), Expect = 0.075
 Identities = 31/161 (19%), Positives = 64/161 (39%), Gaps = 3/161 (1%)

Query: 244 LPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTA 303
           L  +  L+  T++  L  T   L  L  G  E   +++ SG    LV ++     +    
Sbjct: 279 LQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLW 338

Query: 304 ALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQVQA 363
               V  +++        ++    +      L+ P +++ +  +W L N++    +Q   
Sbjct: 339 TTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGM 398

Query: 364 VIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQV 404
               GL+  ++  L   D      AA  +SNLT +  K+++
Sbjct: 399 ---EGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKM 436


>gi|148233338 catenin (cadherin-associated protein), beta 1, 88kDa
           [Homo sapiens]
          Length = 781

 Score = 36.2 bits (82), Expect = 0.075
 Identities = 31/161 (19%), Positives = 64/161 (39%), Gaps = 3/161 (1%)

Query: 244 LPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTA 303
           L  +  L+  T++  L  T   L  L  G  E   +++ SG    LV ++     +    
Sbjct: 279 LQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLW 338

Query: 304 ALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQVQA 363
               V  +++        ++    +      L+ P +++ +  +W L N++    +Q   
Sbjct: 339 TTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGM 398

Query: 364 VIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQV 404
               GL+  ++  L   D      AA  +SNLT +  K+++
Sbjct: 399 ---EGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKM 436


>gi|4503131 catenin (cadherin-associated protein), beta 1, 88kDa
           [Homo sapiens]
          Length = 781

 Score = 36.2 bits (82), Expect = 0.075
 Identities = 31/161 (19%), Positives = 64/161 (39%), Gaps = 3/161 (1%)

Query: 244 LPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTA 303
           L  +  L+  T++  L  T   L  L  G  E   +++ SG    LV ++     +    
Sbjct: 279 LQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLW 338

Query: 304 ALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQVQA 363
               V  +++        ++    +      L+ P +++ +  +W L N++    +Q   
Sbjct: 339 TTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGM 398

Query: 364 VIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQV 404
               GL+  ++  L   D      AA  +SNLT +  K+++
Sbjct: 399 ---EGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKM 436


>gi|146231975 catenin, delta 1 isoform 3A [Homo sapiens]
          Length = 832

 Score = 36.2 bits (82), Expect = 0.075
 Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 6/129 (4%)

Query: 229 RNKDPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPF 288
           R   PPPP     E+   + +L +  D  +  +    L +L    ++    V     +P 
Sbjct: 253 RKGGPPPPNWRQPELPEVIAMLGFRLDA-VKSNAAAYLQHLCYRNDKVKTDVRKLKGIPV 311

Query: 289 LVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVL-NCDVLSHFPNLLSHPKEKINKEAV 347
           LV LL H + +V   A  A+ NI  G D+  ++ + NCD +     LL   ++    E +
Sbjct: 312 LVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVI 371

Query: 348 ----WFLSN 352
               W LS+
Sbjct: 372 TGTLWNLSS 380


>gi|146231948 catenin, delta 1 isoform 3A [Homo sapiens]
          Length = 832

 Score = 36.2 bits (82), Expect = 0.075
 Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 6/129 (4%)

Query: 229 RNKDPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPF 288
           R   PPPP     E+   + +L +  D  +  +    L +L    ++    V     +P 
Sbjct: 253 RKGGPPPPNWRQPELPEVIAMLGFRLDA-VKSNAAAYLQHLCYRNDKVKTDVRKLKGIPV 311

Query: 289 LVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVL-NCDVLSHFPNLLSHPKEKINKEAV 347
           LV LL H + +V   A  A+ NI  G D+  ++ + NCD +     LL   ++    E +
Sbjct: 312 LVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVI 371

Query: 348 ----WFLSN 352
               W LS+
Sbjct: 372 TGTLWNLSS 380


>gi|146231994 catenin, delta 1 isoform 3A [Homo sapiens]
          Length = 832

 Score = 36.2 bits (82), Expect = 0.075
 Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 6/129 (4%)

Query: 229 RNKDPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPF 288
           R   PPPP     E+   + +L +  D  +  +    L +L    ++    V     +P 
Sbjct: 253 RKGGPPPPNWRQPELPEVIAMLGFRLDA-VKSNAAAYLQHLCYRNDKVKTDVRKLKGIPV 311

Query: 289 LVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVL-NCDVLSHFPNLLSHPKEKINKEAV 347
           LV LL H + +V   A  A+ NI  G D+  ++ + NCD +     LL   ++    E +
Sbjct: 312 LVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVI 371

Query: 348 ----WFLSN 352
               W LS+
Sbjct: 372 TGTLWNLSS 380


>gi|146231977 catenin, delta 1 isoform 3AC [Homo sapiens]
          Length = 838

 Score = 36.2 bits (82), Expect = 0.075
 Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 6/129 (4%)

Query: 229 RNKDPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPF 288
           R   PPPP     E+   + +L +  D  +  +    L +L    ++    V     +P 
Sbjct: 253 RKGGPPPPNWRQPELPEVIAMLGFRLDA-VKSNAAAYLQHLCYRNDKVKTDVRKLKGIPV 311

Query: 289 LVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVL-NCDVLSHFPNLLSHPKEKINKEAV 347
           LV LL H + +V   A  A+ NI  G D+  ++ + NCD +     LL   ++    E +
Sbjct: 312 LVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVI 371

Query: 348 ----WFLSN 352
               W LS+
Sbjct: 372 TGTLWNLSS 380


>gi|146231946 catenin, delta 1 isoform 3B [Homo sapiens]
          Length = 840

 Score = 36.2 bits (82), Expect = 0.075
 Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 6/129 (4%)

Query: 229 RNKDPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPF 288
           R   PPPP     E+   + +L +  D  +  +    L +L    ++    V     +P 
Sbjct: 253 RKGGPPPPNWRQPELPEVIAMLGFRLDA-VKSNAAAYLQHLCYRNDKVKTDVRKLKGIPV 311

Query: 289 LVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVL-NCDVLSHFPNLLSHPKEKINKEAV 347
           LV LL H + +V   A  A+ NI  G D+  ++ + NCD +     LL   ++    E +
Sbjct: 312 LVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVI 371

Query: 348 ----WFLSN 352
               W LS+
Sbjct: 372 TGTLWNLSS 380


>gi|146231991 catenin, delta 1 isoform 3AB [Homo sapiens]
          Length = 861

 Score = 36.2 bits (82), Expect = 0.075
 Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 6/129 (4%)

Query: 229 RNKDPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPF 288
           R   PPPP     E+   + +L +  D  +  +    L +L    ++    V     +P 
Sbjct: 253 RKGGPPPPNWRQPELPEVIAMLGFRLDA-VKSNAAAYLQHLCYRNDKVKTDVRKLKGIPV 311

Query: 289 LVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVL-NCDVLSHFPNLLSHPKEKINKEAV 347
           LV LL H + +V   A  A+ NI  G D+  ++ + NCD +     LL   ++    E +
Sbjct: 312 LVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVI 371

Query: 348 ----WFLSN 352
               W LS+
Sbjct: 372 TGTLWNLSS 380


>gi|146231970 catenin, delta 1 isoform 3ABC [Homo sapiens]
          Length = 867

 Score = 36.2 bits (82), Expect = 0.075
 Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 6/129 (4%)

Query: 229 RNKDPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPF 288
           R   PPPP     E+   + +L +  D  +  +    L +L    ++    V     +P 
Sbjct: 253 RKGGPPPPNWRQPELPEVIAMLGFRLDA-VKSNAAAYLQHLCYRNDKVKTDVRKLKGIPV 311

Query: 289 LVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVL-NCDVLSHFPNLLSHPKEKINKEAV 347
           LV LL H + +V   A  A+ NI  G D+  ++ + NCD +     LL   ++    E +
Sbjct: 312 LVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVI 371

Query: 348 ----WFLSN 352
               W LS+
Sbjct: 372 TGTLWNLSS 380


>gi|146231942 catenin, delta 1 isoform 1A [Homo sapiens]
          Length = 933

 Score = 36.2 bits (82), Expect = 0.075
 Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 6/129 (4%)

Query: 229 RNKDPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPF 288
           R   PPPP     E+   + +L +  D  +  +    L +L    ++    V     +P 
Sbjct: 354 RKGGPPPPNWRQPELPEVIAMLGFRLDA-VKSNAAAYLQHLCYRNDKVKTDVRKLKGIPV 412

Query: 289 LVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVL-NCDVLSHFPNLLSHPKEKINKEAV 347
           LV LL H + +V   A  A+ NI  G D+  ++ + NCD +     LL   ++    E +
Sbjct: 413 LVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVI 472

Query: 348 ----WFLSN 352
               W LS+
Sbjct: 473 TGTLWNLSS 481


>gi|146231968 catenin, delta 1 isoform 1A [Homo sapiens]
          Length = 933

 Score = 36.2 bits (82), Expect = 0.075
 Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 6/129 (4%)

Query: 229 RNKDPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPF 288
           R   PPPP     E+   + +L +  D  +  +    L +L    ++    V     +P 
Sbjct: 354 RKGGPPPPNWRQPELPEVIAMLGFRLDA-VKSNAAAYLQHLCYRNDKVKTDVRKLKGIPV 412

Query: 289 LVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVL-NCDVLSHFPNLLSHPKEKINKEAV 347
           LV LL H + +V   A  A+ NI  G D+  ++ + NCD +     LL   ++    E +
Sbjct: 413 LVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVI 472

Query: 348 ----WFLSN 352
               W LS+
Sbjct: 473 TGTLWNLSS 481


>gi|146231938 catenin, delta 1 isoform 1A [Homo sapiens]
          Length = 933

 Score = 36.2 bits (82), Expect = 0.075
 Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 6/129 (4%)

Query: 229 RNKDPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPF 288
           R   PPPP     E+   + +L +  D  +  +    L +L    ++    V     +P 
Sbjct: 354 RKGGPPPPNWRQPELPEVIAMLGFRLDA-VKSNAAAYLQHLCYRNDKVKTDVRKLKGIPV 412

Query: 289 LVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVL-NCDVLSHFPNLLSHPKEKINKEAV 347
           LV LL H + +V   A  A+ NI  G D+  ++ + NCD +     LL   ++    E +
Sbjct: 413 LVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVI 472

Query: 348 ----WFLSN 352
               W LS+
Sbjct: 473 TGTLWNLSS 481


>gi|10835010 catenin, delta 1 isoform 1B [Homo sapiens]
          Length = 941

 Score = 36.2 bits (82), Expect = 0.075
 Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 6/129 (4%)

Query: 229 RNKDPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPF 288
           R   PPPP     E+   + +L +  D  +  +    L +L    ++    V     +P 
Sbjct: 354 RKGGPPPPNWRQPELPEVIAMLGFRLDA-VKSNAAAYLQHLCYRNDKVKTDVRKLKGIPV 412

Query: 289 LVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVL-NCDVLSHFPNLLSHPKEKINKEAV 347
           LV LL H + +V   A  A+ NI  G D+  ++ + NCD +     LL   ++    E +
Sbjct: 413 LVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVI 472

Query: 348 ----WFLSN 352
               W LS+
Sbjct: 473 TGTLWNLSS 481


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,730,185
Number of Sequences: 37866
Number of extensions: 851173
Number of successful extensions: 2728
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 59
Number of HSP's that attempted gapping in prelim test: 2456
Number of HSP's gapped (non-prelim): 163
length of query: 521
length of database: 18,247,518
effective HSP length: 107
effective length of query: 414
effective length of database: 14,195,856
effective search space: 5877084384
effective search space used: 5877084384
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.