Guide to the Human Genome
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Search of human proteins with 34303926

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|34303926 prolyl-tRNA synthetase (mitochondrial)(putative)
[Homo sapiens]
         (475 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|34303926 prolyl-tRNA synthetase (mitochondrial)(putative) [Ho...   972   0.0  
gi|116805340 glycyl-tRNA synthetase [Homo sapiens]                     40   0.006
gi|20070344 threonyl-tRNA synthetase 2, mitochondrial [Homo sapi...    38   0.023
gi|38202255 threonyl-tRNA synthetase [Homo sapiens]                    37   0.051
gi|62241042 glutamyl-prolyl tRNA synthetase [Homo sapiens]             35   0.11 
gi|157426898 tripartite motif-containing 10 isoform 1 [Homo sapi...    31   2.8  
gi|157426896 tripartite motif-containing 10 isoform 2 [Homo sapi...    31   2.8  
gi|67188550 CTD (carboxy-terminal domain, RNA polymerase II, pol...    30   4.8  
gi|67188445 CTD (carboxy-terminal domain, RNA polymerase II, pol...    30   4.8  
gi|38570111 threonyl-tRNA synthetase-like 2 [Homo sapiens]             30   6.3  
gi|219842266 usherin isoform B [Homo sapiens]                          29   8.2  
gi|219842259 usherin isoform A [Homo sapiens]                          29   8.2  
gi|24308171 zinc finger protein 280C [Homo sapiens]                    29   8.2  

>gi|34303926 prolyl-tRNA synthetase (mitochondrial)(putative) [Homo
           sapiens]
          Length = 475

 Score =  972 bits (2514), Expect = 0.0
 Identities = 475/475 (100%), Positives = 475/475 (100%)

Query: 1   MEGLLTRCRALPALATCSRQLSGYVPCRFHHCAPRRGRRLLLSRVFQPQNLREDRVLSLQ 60
           MEGLLTRCRALPALATCSRQLSGYVPCRFHHCAPRRGRRLLLSRVFQPQNLREDRVLSLQ
Sbjct: 1   MEGLLTRCRALPALATCSRQLSGYVPCRFHHCAPRRGRRLLLSRVFQPQNLREDRVLSLQ 60

Query: 61  DKSDDLTCKSQRLMLQVGLIYPASPGCYHLLPYTVRAMEKLVRVIDQEMQAIGGQKVNMP 120
           DKSDDLTCKSQRLMLQVGLIYPASPGCYHLLPYTVRAMEKLVRVIDQEMQAIGGQKVNMP
Sbjct: 61  DKSDDLTCKSQRLMLQVGLIYPASPGCYHLLPYTVRAMEKLVRVIDQEMQAIGGQKVNMP 120

Query: 121 SLSPAELWQATNRWDLMGKELLRLRDRHGKEYCLGPTHEEAITALIASQKKLSYKQLPFL 180
           SLSPAELWQATNRWDLMGKELLRLRDRHGKEYCLGPTHEEAITALIASQKKLSYKQLPFL
Sbjct: 121 SLSPAELWQATNRWDLMGKELLRLRDRHGKEYCLGPTHEEAITALIASQKKLSYKQLPFL 180

Query: 181 LYQVTRKFRDEPRPRFGLLRGREFYMKDMYTFDSSPEAAQQTYSLVCDAYCSLFNKLGLP 240
           LYQVTRKFRDEPRPRFGLLRGREFYMKDMYTFDSSPEAAQQTYSLVCDAYCSLFNKLGLP
Sbjct: 181 LYQVTRKFRDEPRPRFGLLRGREFYMKDMYTFDSSPEAAQQTYSLVCDAYCSLFNKLGLP 240

Query: 241 FVKVQADVGTIGGTVSHEFQLPVDIGEDRLAICPRCSFSANMETLDLSQMNCPACQGPLT 300
           FVKVQADVGTIGGTVSHEFQLPVDIGEDRLAICPRCSFSANMETLDLSQMNCPACQGPLT
Sbjct: 241 FVKVQADVGTIGGTVSHEFQLPVDIGEDRLAICPRCSFSANMETLDLSQMNCPACQGPLT 300

Query: 301 KTKGIEVGHTFYLGTKYSSIFNAQFTNVCGKPTLAEMGCYGLGVTRILAAAIEVLSTEDC 360
           KTKGIEVGHTFYLGTKYSSIFNAQFTNVCGKPTLAEMGCYGLGVTRILAAAIEVLSTEDC
Sbjct: 301 KTKGIEVGHTFYLGTKYSSIFNAQFTNVCGKPTLAEMGCYGLGVTRILAAAIEVLSTEDC 360

Query: 361 VRWPSLLAPYQACLIPPKKGSKEQAASELIGQLYDHITEAVPQLHGEVLLDDRTHLTIGN 420
           VRWPSLLAPYQACLIPPKKGSKEQAASELIGQLYDHITEAVPQLHGEVLLDDRTHLTIGN
Sbjct: 361 VRWPSLLAPYQACLIPPKKGSKEQAASELIGQLYDHITEAVPQLHGEVLLDDRTHLTIGN 420

Query: 421 RLKDANKFGYPFVIIAGKRALEDPAHFEVWCQNTGEVAFLTKDGVMDLLTPVQTV 475
           RLKDANKFGYPFVIIAGKRALEDPAHFEVWCQNTGEVAFLTKDGVMDLLTPVQTV
Sbjct: 421 RLKDANKFGYPFVIIAGKRALEDPAHFEVWCQNTGEVAFLTKDGVMDLLTPVQTV 475


>gi|116805340 glycyl-tRNA synthetase [Homo sapiens]
          Length = 739

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 21/60 (35%), Positives = 31/60 (51%)

Query: 176 QLPFLLYQVTRKFRDEPRPRFGLLRGREFYMKDMYTFDSSPEAAQQTYSLVCDAYCSLFN 235
           +LPF   Q+   FR+E  PR GL+R REF M ++  F    E     +  V D +  L++
Sbjct: 318 KLPFAAAQIGNSFRNEISPRSGLIRVREFTMAEIEHFVDPSEKDHPKFQNVADLHLYLYS 377


>gi|20070344 threonyl-tRNA synthetase 2, mitochondrial [Homo
           sapiens]
          Length = 718

 Score = 37.7 bits (86), Expect = 0.023
 Identities = 83/389 (21%), Positives = 137/389 (35%), Gaps = 65/389 (16%)

Query: 84  SPGCYHLLPYTVRAMEKLVRVIDQEMQAIGGQKVNMPSLSPAELWQATNRWDLMGKELLR 143
           SPG    LP   R    LV  I  E    G  +V  P+L   +LW+ +  W+   +++  
Sbjct: 318 SPGSCFFLPRGTRVYNALVAFIRAEYAHRGFSEVKTPTLFSTKLWEQSGHWEHYQEDMFA 377

Query: 144 LR----DRHGKEYCLGPTHEEAIT-----------ALIASQKKLSYKQLPFLLYQVTRKF 188
           ++    DR         T     T            L+ + +  S+++LP  L       
Sbjct: 378 VQPPGSDRPPSSQSDDSTRHITDTLALKPMNCPAHCLMFAHRPRSWRELPLRLADFGALH 437

Query: 189 RDEPRPRF-GLLRGREFYMKDMYTFDSSPEAAQQTYSLVCDAYCSLFNKLGLPF--VKVQ 245
           R E      GL R R F   D + F ++ +   +  S + D   S++  LG  F      
Sbjct: 438 RAEASGGLGGLTRLRCFQQDDAHIFCTTDQLEAEIQSCL-DFLRSVYAVLGFSFRLALST 496

Query: 246 ADVGTIGG------------TVSHEFQLPVDIGEDRLAICPRCSFSANMETLDLSQMNCP 293
              G +G                 EF  P D+     A      +   ++      +  P
Sbjct: 497 RPSGFLGDPCLWDQAEQVLKQALKEFGEPWDLNSGDGAF-----YGPKIDVHLHDALGRP 551

Query: 294 ACQGPLTKTKGIEVGHTFYLGTKYSSIFNAQFTNVCGKPTLAEMGCYGLGVTRILAAAIE 353
              G +           F L  ++   +  Q      +P L      G  V R+L     
Sbjct: 552 HQCGTIQL--------DFQLPLRFDLQYKGQ-AGALERPVLIHRAVLG-SVERLLG---- 597

Query: 354 VLSTEDCVRWPSLLAPYQACLIPPKKGSKEQAASELIGQLYDHITEAVPQLHGEVL---L 410
           VL+     +WP  L+P+Q  +IP   GS+++          ++  EA   L    L   L
Sbjct: 598 VLAESCGGKWPLWLSPFQVVVIP--VGSEQE----------EYAKEAQQSLRAAGLVSDL 645

Query: 411 DDRTHLTIGNRLKDANKFGYPFVIIAGKR 439
           D  + LT+  R++ A    Y F  + G++
Sbjct: 646 DADSGLTLSRRIRRAQLAHYNFQFVVGQK 674


>gi|38202255 threonyl-tRNA synthetase [Homo sapiens]
          Length = 723

 Score = 36.6 bits (83), Expect = 0.051
 Identities = 35/139 (25%), Positives = 52/139 (37%), Gaps = 21/139 (15%)

Query: 84  SPGCYHLLPYTVRAMEKLVRVIDQEMQAIGGQKVNMPSLSPAELWQATNRWD-------- 135
           SPG    LP        L+  I  E +  G Q+V  P++  + LW  +  W         
Sbjct: 339 SPGSCFFLPKGAYIYNALIEFIRSEYRKRGFQEVVTPNIFNSRLWMTSGHWQHYSENMFS 398

Query: 136 -LMGKELLRLRDRHGKEYCLGPTHEEAITALIASQKKLSYKQLPFLLYQVTRKFRDEPRP 194
             + KEL  L+  +   +CL   H           +  S+++LP  L       R+E   
Sbjct: 399 FEVEKELFALKPMNCPGHCLMFDH-----------RPRSWRELPLRLADFGVLHRNELSG 447

Query: 195 RF-GLLRGREFYMKDMYTF 212
              GL R R F   D + F
Sbjct: 448 ALTGLTRVRRFQQDDAHIF 466


>gi|62241042 glutamyl-prolyl tRNA synthetase [Homo sapiens]
          Length = 1512

 Score = 35.4 bits (80), Expect = 0.11
 Identities = 50/217 (23%), Positives = 88/217 (40%), Gaps = 11/217 (5%)

Query: 36   RGRRLLLSRVFQPQNLREDRVLSLQDKSDDLTCK--SQRLMLQVGLIYPASPGCYHLLPY 93
            +G  L  S   + Q  ++   L L+ K ++      SQ +     + Y    GCY L P+
Sbjct: 993  QGGGLSSSGAGEGQGPKKQTRLGLEAKKEENLADWYSQVITKSEMIEYHDISGCYILRPW 1052

Query: 94   TVRAMEKLVRVIDQEMQAIGGQKVNMPS-LSPAELWQATNRWDLMGKELLRLRDRHGKE- 151
                 E +    D E++ +G +    P  +S + L +          E+  +  R GK  
Sbjct: 1053 AYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWVT-RSGKTE 1111

Query: 152  ----YCLGPTHEEAITALIASQKKLSYKQLPFLLYQVTRKFRDEPRPRFGLLRGREFYMK 207
                  + PT E  +    A   + S++ LP  L Q     R E +     LR REF  +
Sbjct: 1112 LAEPIAIRPTSETVMYPAYAKWVQ-SHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQ 1170

Query: 208  DMYTFDSSPEAAQQTYSLVCDAYCSLFNK-LGLPFVK 243
            + ++  ++ E A +    + D Y  ++ + L +P VK
Sbjct: 1171 EGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVK 1207


>gi|157426898 tripartite motif-containing 10 isoform 1 [Homo
           sapiens]
          Length = 481

 Score = 30.8 bits (68), Expect = 2.8
 Identities = 14/33 (42%), Positives = 18/33 (54%)

Query: 279 SANMETLDLSQMNCPACQGPLTKTKGIEVGHTF 311
           SA   T    ++NCP CQG L +   I+ GH F
Sbjct: 3   SAASVTSLADEVNCPICQGTLREPVTIDCGHNF 35


>gi|157426896 tripartite motif-containing 10 isoform 2 [Homo
           sapiens]
          Length = 395

 Score = 30.8 bits (68), Expect = 2.8
 Identities = 14/33 (42%), Positives = 18/33 (54%)

Query: 279 SANMETLDLSQMNCPACQGPLTKTKGIEVGHTF 311
           SA   T    ++NCP CQG L +   I+ GH F
Sbjct: 3   SAASVTSLADEVNCPICQGTLREPVTIDCGHNF 35


>gi|67188550 CTD (carboxy-terminal domain, RNA polymerase II,
           polypeptide A) phosphatase, subunit 1 isoform FCP1b
           [Homo sapiens]
          Length = 867

 Score = 30.0 bits (66), Expect = 4.8
 Identities = 12/29 (41%), Positives = 17/29 (58%)

Query: 122 LSPAELWQATNRWDLMGKELLRLRDRHGK 150
           ++P  LW    RWD + ++L  LRD H K
Sbjct: 706 VNPDWLWSCLERWDKVEEQLFPLRDDHTK 734


>gi|67188445 CTD (carboxy-terminal domain, RNA polymerase II,
           polypeptide A) phosphatase, subunit 1 isoform FCP1a
           [Homo sapiens]
          Length = 961

 Score = 30.0 bits (66), Expect = 4.8
 Identities = 12/29 (41%), Positives = 17/29 (58%)

Query: 122 LSPAELWQATNRWDLMGKELLRLRDRHGK 150
           ++P  LW    RWD + ++L  LRD H K
Sbjct: 706 VNPDWLWSCLERWDKVEEQLFPLRDDHTK 734


>gi|38570111 threonyl-tRNA synthetase-like 2 [Homo sapiens]
          Length = 802

 Score = 29.6 bits (65), Expect = 6.3
 Identities = 29/133 (21%), Positives = 50/133 (37%), Gaps = 9/133 (6%)

Query: 84  SPGCYHLLPYTVRAMEKLVRVIDQEMQAIGGQKVNMPSLSPAELWQATNRWDLMGKELLR 143
           SPG    LP        L   I +E       +V  P++  ++LW+A+  W    + +  
Sbjct: 418 SPGSCFFLPRGAFIYNTLTDFIREEYHKRDFTEVLSPNMYNSKLWEASGHWQHYSENMFT 477

Query: 144 L---RDRHGKEYCLGPTHEEAITALIASQKKLSYKQLPFLLYQVTRKFRDEPRPRF-GLL 199
               +D    +    P H      L+ + +  S++++P          R+E      GL 
Sbjct: 478 FEIEKDTFALKPMNCPGH-----CLMFAHRPRSWREMPIRFADFGVLHRNELSGTLSGLT 532

Query: 200 RGREFYMKDMYTF 212
           R R F   D + F
Sbjct: 533 RVRRFQQDDAHIF 545


>gi|219842266 usherin isoform B [Homo sapiens]
          Length = 5202

 Score = 29.3 bits (64), Expect = 8.2
 Identities = 21/69 (30%), Positives = 33/69 (47%), Gaps = 1/69 (1%)

Query: 84   SPGCYHLLPYTV-RAMEKLVRVIDQEMQAIGGQKVNMPSLSPAELWQATNRWDLMGKELL 142
            S GC H LP TV  A     R+   +MQ I   ++++    PAEL     R++L  + L 
Sbjct: 1225 SGGCLHSLPITVTTAQAPPQRLSPPKMQKISSTELHVEWSPPAELNGIIIRYELYMRRLR 1284

Query: 143  RLRDRHGKE 151
              ++   +E
Sbjct: 1285 STKETTSEE 1293


>gi|219842259 usherin isoform A [Homo sapiens]
          Length = 1546

 Score = 29.3 bits (64), Expect = 8.2
 Identities = 21/69 (30%), Positives = 33/69 (47%), Gaps = 1/69 (1%)

Query: 84   SPGCYHLLPYTV-RAMEKLVRVIDQEMQAIGGQKVNMPSLSPAELWQATNRWDLMGKELL 142
            S GC H LP TV  A     R+   +MQ I   ++++    PAEL     R++L  + L 
Sbjct: 1225 SGGCLHSLPITVTTAQAPPQRLSPPKMQKISSTELHVEWSPPAELNGIIIRYELYMRRLR 1284

Query: 143  RLRDRHGKE 151
              ++   +E
Sbjct: 1285 STKETTSEE 1293


>gi|24308171 zinc finger protein 280C [Homo sapiens]
          Length = 737

 Score = 29.3 bits (64), Expect = 8.2
 Identities = 16/47 (34%), Positives = 23/47 (48%), Gaps = 3/47 (6%)

Query: 262 PVDIGEDRLAICPRCSFSAN-METLDLSQMNCPACQGPLTKTKGIEV 307
           P D G D L  CP+C+   N ++ L     +C  C   +TK  G+ V
Sbjct: 228 PYDAGADYLRACPKCNVQFNLLDPLKYHMKHC--CPDMITKFLGVIV 272


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.138    0.426 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,335,799
Number of Sequences: 37866
Number of extensions: 809999
Number of successful extensions: 1616
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1603
Number of HSP's gapped (non-prelim): 17
length of query: 475
length of database: 18,247,518
effective HSP length: 106
effective length of query: 369
effective length of database: 14,233,722
effective search space: 5252243418
effective search space used: 5252243418
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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