Search of human proteins with 34013590

Search of human proteins with 34013590

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]
         (698 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]           1398   0.0  
gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo sa...   578   e-165
gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo sa...   488   e-138
gi|55770898 Rho GTPase activating protein 25 isoform a [Homo sap...   466   e-131
gi|7661882 Rho GTPase activating protein 25 isoform b [Homo sapi...   462   e-130
gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo sa...   438   e-123
gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]       120   4e-27
gi|75677374 SLIT-ROBO Rho GTPase activating protein 3 isoform b ...   117   5e-26
gi|24307967 SLIT-ROBO Rho GTPase activating protein 3 isoform a ...   117   5e-26
gi|44917604 SLIT-ROBO Rho GTPase activating protein 1 [Homo sapi...   114   2e-25
gi|54860079 nadrin isoform 1 [Homo sapiens]                           114   3e-25
gi|54860105 nadrin isoform 2 [Homo sapiens]                           114   3e-25
gi|4757766 Rho GTPase activating protein 1 [Homo sapiens]             112   1e-24
gi|112363100 SLIT-ROBO Rho GTPase activating protein 2 isoform a...   109   8e-24
gi|112363096 SLIT-ROBO Rho GTPase activating protein 2 isoform b...   109   8e-24
gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sa...   108   2e-23
gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sap...   108   2e-23
gi|85815829 SH3-domain binding protein 1 [Homo sapiens]               106   6e-23
gi|56119110 family with sequence similarity 13, member A1 isofor...   105   1e-22
gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]          103   4e-22
gi|226423858 PRR5-ARHGAP8 fusion protein [Homo sapiens]               103   7e-22
gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens]        103   7e-22
gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens]        103   7e-22
gi|66346660 Rho GTPase activating protein 8 isoform 2 [Homo sapi...   103   7e-22
gi|66346662 Rho GTPase activating protein 8 isoform 1 [Homo sapi...   103   7e-22
gi|156071465 Rho GTPase activating protein 4 [Homo sapiens]           102   1e-21
gi|91208437 GEM interacting protein [Homo sapiens]                    101   2e-21
gi|194272142 myosin IXB isoform 2 [Homo sapiens]                      100   3e-21
gi|33356170 myosin IXB isoform 1 [Homo sapiens]                       100   3e-21
gi|50843948 Rho GTPase activating protein 10 [Homo sapiens]           100   5e-21

>gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]
          Length = 698

 Score = 1398 bits (3618), Expect = 0.0
 Identities = 698/698 (100%), Positives = 698/698 (100%)

Query: 1   MLSPKIRQARRARSKSLVMGEQSRSPGRMPCPHRLGPVLKAGWLKKQRSIMKNWQQRWFV 60
           MLSPKIRQARRARSKSLVMGEQSRSPGRMPCPHRLGPVLKAGWLKKQRSIMKNWQQRWFV
Sbjct: 1   MLSPKIRQARRARSKSLVMGEQSRSPGRMPCPHRLGPVLKAGWLKKQRSIMKNWQQRWFV 60

Query: 61  LRGDQLFYYKDKDEIKPQGFISLQGTQVTELPPGPEDPGKHLFEISPGGAGEREKVPANP 120
           LRGDQLFYYKDKDEIKPQGFISLQGTQVTELPPGPEDPGKHLFEISPGGAGEREKVPANP
Sbjct: 61  LRGDQLFYYKDKDEIKPQGFISLQGTQVTELPPGPEDPGKHLFEISPGGAGEREKVPANP 120

Query: 121 EALLLMASSQRDMEDWVQAIRRVIWAPLGGGIFGQRLEETVHHERKYGPRLAPLLVEQCV 180
           EALLLMASSQRDMEDWVQAIRRVIWAPLGGGIFGQRLEETVHHERKYGPRLAPLLVEQCV
Sbjct: 121 EALLLMASSQRDMEDWVQAIRRVIWAPLGGGIFGQRLEETVHHERKYGPRLAPLLVEQCV 180

Query: 181 DFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASLLKLYLRELPE 240
           DFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASLLKLYLRELPE
Sbjct: 181 DFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASLLKLYLRELPE 240

Query: 241 PVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKFLDEVQAYSNV 300
           PVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKFLDEVQAYSNV
Sbjct: 241 PVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKFLDEVQAYSNV 300

Query: 301 NKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIRKHSQLFTAPVPEGPTSP 360
           NKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIRKHSQLFTAPVPEGPTSP
Sbjct: 301 NKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIRKHSQLFTAPVPEGPTSP 360

Query: 361 RGGLQCAVGWGSEEVTRDSQGEPGGPGLPAHRTSSLDGAAVAVLSRTAPTGPGSRCSPGK 420
           RGGLQCAVGWGSEEVTRDSQGEPGGPGLPAHRTSSLDGAAVAVLSRTAPTGPGSRCSPGK
Sbjct: 361 RGGLQCAVGWGSEEVTRDSQGEPGGPGLPAHRTSSLDGAAVAVLSRTAPTGPGSRCSPGK 420

Query: 421 KVQTLPSWKSSFRQPRSLSGSPKGGGSSLEVPIISSGGNWLMNGLSSLRGHRRASSGDRL 480
           KVQTLPSWKSSFRQPRSLSGSPKGGGSSLEVPIISSGGNWLMNGLSSLRGHRRASSGDRL
Sbjct: 421 KVQTLPSWKSSFRQPRSLSGSPKGGGSSLEVPIISSGGNWLMNGLSSLRGHRRASSGDRL 480

Query: 481 KDSGSVQRLSTYDNVPAPGLVPGIPSVASMAWSGASSSESSVGGSLSSCTACRASDSSAR 540
           KDSGSVQRLSTYDNVPAPGLVPGIPSVASMAWSGASSSESSVGGSLSSCTACRASDSSAR
Sbjct: 481 KDSGSVQRLSTYDNVPAPGLVPGIPSVASMAWSGASSSESSVGGSLSSCTACRASDSSAR 540

Query: 541 SSLHTDWALEPSPLPSSSEDPKSLDLDHSMDEAGAGASNSEPSEPDSPTREHARRSEALQ 600
           SSLHTDWALEPSPLPSSSEDPKSLDLDHSMDEAGAGASNSEPSEPDSPTREHARRSEALQ
Sbjct: 541 SSLHTDWALEPSPLPSSSEDPKSLDLDHSMDEAGAGASNSEPSEPDSPTREHARRSEALQ 600

Query: 601 GLVTELRAELCRQRTEYERSVKRIEEGSADLRKRMSRLEEELDQEKKKYIMLEIKLRNSE 660
           GLVTELRAELCRQRTEYERSVKRIEEGSADLRKRMSRLEEELDQEKKKYIMLEIKLRNSE
Sbjct: 601 GLVTELRAELCRQRTEYERSVKRIEEGSADLRKRMSRLEEELDQEKKKYIMLEIKLRNSE 660

Query: 661 RAREDAERRNQLLQREMEEFFSTLGSLTVGAKGARAPK 698
           RAREDAERRNQLLQREMEEFFSTLGSLTVGAKGARAPK
Sbjct: 661 RAREDAERRNQLLQREMEEFFSTLGSLTVGAKGARAPK 698


>gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo
           sapiens]
          Length = 748

 Score =  578 bits (1491), Expect = e-165
 Identities = 344/726 (47%), Positives = 447/726 (61%), Gaps = 87/726 (11%)

Query: 39  LKAGWLKKQRSIMKNWQQRWFVLRGDQLFYYKDKDEIKPQGFISLQGTQVTELPPGPEDP 98
           +K GWL+KQ   +K W  RWFVL+GDQL+Y+KD+DE KP G I L G +V+E P   E+P
Sbjct: 21  IKCGWLRKQGGFVKTWHTRWFVLKGDQLYYFKDEDETKPLGTIFLPGNKVSEHPCNEENP 80

Query: 99  GKHLFEISPGGAGEREKVPANPEALLLMASSQRDMEDWVQAIRRVIWAPLGGGIFGQRLE 158
           GK LFE+ PGG  +R+++ AN E+ LLMAS+Q DMEDWV++IRRVIW P GGGIFGQ+LE
Sbjct: 81  GKFLFEVVPGG--DRDRMTANHESYLLMASTQNDMEDWVKSIRRVIWGPFGGGIFGQKLE 138

Query: 159 ETVHHERKYGPRLAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLF 218
           +TV +E++YG RLAP+LVEQCVDFIR+RGL EEGLFR+PGQANLV++LQD+FDCGEKP F
Sbjct: 139 DTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSF 198

Query: 219 DSTTDVHTVASLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQ 278
           DS TDVHTVASLLKLYLRELPEPV+P+A+YEDFLSCA+LL+K+E  G  ELAKQV +LP 
Sbjct: 199 DSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPV 258

Query: 279 ANYNLLRYICKFLDEVQAYSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLM 338
            NYNLL+YIC+FLDEVQ+YS VNKMSVQNLATVFGPNILRP+VEDP+TIMEGT +VQ LM
Sbjct: 259 VNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLM 318

Query: 339 TVLIRKHSQLFTAPVPEGPTSPRGGL-----------------------------QCAVG 369
           +V+I KH  LF     E  + P+ G+                             QC+  
Sbjct: 319 SVMISKHDCLFPKDA-ELQSKPQDGVSNNNEIQKKATMGQLQNKENNNTKDSPSRQCS-- 375

Query: 370 WGSEEVTRDSQGEPGGP-GLPAHRTSSLDGAAVAV-LSRTAP----------TGPG---- 413
           W   E  + S    G P  L   +T+S   +   + +SR+ P           G G    
Sbjct: 376 WDKSESPQRSSMNNGSPTALSGSKTNSPKNSVHKLDVSRSPPLMVKKNPAFNKGSGIVTN 435

Query: 414 -----SRCSPGKKVQTLPSWKSSFRQPRSL--SGSPKGGGS----SLEVPIISSG--GN- 459
                S     +K QT P+     R+  SL  SG+  G  S    ++ + I++S   GN 
Sbjct: 436 GSFSSSNAEGLEKTQTTPNGSLQARRSSSLKVSGTKMGTHSVQNGTVRMGILNSDTLGNP 495

Query: 460 -------WLMNGLSSLRGHRRASSGDRLKDSGSVQRLSTYDNVPAPGLVPGI---PSVAS 509
                  WL NG  +LR +++      L   G   RLSTYDNV     +  +    S+ S
Sbjct: 496 TNVRNMSWLPNGYVTLRDNKQKEQAGEL---GQHNRLSTYDNVHQQFSMMNLDDKQSIDS 552

Query: 510 MAWSGASSSESSVGGSLSSC----TACRASDSSARSSLHTDWALEPSPLPSSSEDPKSLD 565
             WS  SS E S+  + +SC    T C   D    +    D  L+  P    S  P+  +
Sbjct: 553 ATWS-TSSCEISLPENSNSCRSSTTTCPEQDFFGGN--FEDPVLDGPPQDDLSH-PRDYE 608

Query: 566 LDHSMDEAGAGASNSEPSEPDSPT--REHARRSEALQGLVTELRAELCRQRTEYERSVKR 623
                   G  +S +  S  +S T     +    AL  LV+ L+ E+ +Q+ EYE  +K 
Sbjct: 609 SKSDHRSVGGRSSRATSSSDNSETFVGNSSSNHSALHSLVSSLKQEMTKQKIEYESRIKS 668

Query: 624 IEEGSADLRKRMSRLEEELDQEKKKYIMLEIKLRNSERAREDAERRNQLLQREMEEFFST 683
           +E+ +  L   M  L +ELDQE+KK+ M+EIK+RN+ERA+EDAE+RN +LQ+EME+FFST
Sbjct: 669 LEQRNLTLETEMMSLHDELDQERKKFTMIEIKMRNAERAKEDAEKRNDMLQKEMEQFFST 728

Query: 684 LGSLTV 689
            G LTV
Sbjct: 729 FGELTV 734


>gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo
           sapiens]
          Length = 653

 Score =  488 bits (1257), Expect = e-138
 Identities = 302/647 (46%), Positives = 390/647 (60%), Gaps = 85/647 (13%)

Query: 118 ANPEALLLMASSQRDMEDWVQAIRRVIWAPLGGGIFGQRLEETVHHERKYGPRLAPLLVE 177
           AN E+ LLMAS+Q DMEDWV++IRRVIW P GGGIFGQ+LE+TV +E++YG RLAP+LVE
Sbjct: 3   ANHESYLLMASTQNDMEDWVKSIRRVIWGPFGGGIFGQKLEDTVRYEKRYGNRLAPMLVE 62

Query: 178 QCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASLLKLYLRE 237
           QCVDFIR+RGL EEGLFR+PGQANLV++LQD+FDCGEKP FDS TDVHTVASLLKLYLRE
Sbjct: 63  QCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYLRE 122

Query: 238 LPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKFLDEVQAY 297
           LPEPV+P+A+YEDFLSCA+LL+K+E  G  ELAKQV +LP  NYNLL+YIC+FLDEVQ+Y
Sbjct: 123 LPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQSY 182

Query: 298 SNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIRKHSQLFTAPVPEGP 357
           S VNKMSVQNLATVFGPNILRP+VEDP+TIMEGT +VQ LM+V+I KH  LF     E  
Sbjct: 183 SGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKHDCLFPKDA-ELQ 241

Query: 358 TSPRGGL-----------------------------QCAVGWGSEEVTRDSQGEPGGP-G 387
           + P+ G+                             QC+  W   E  + S    G P  
Sbjct: 242 SKPQDGVSNNNEIQKKATMGQLQNKENNNTKDSPSRQCS--WDKSESPQRSSMNNGSPTA 299

Query: 388 LPAHRTSSLDGAAVAV-LSRTAP----------TGPG---------SRCSPGKKVQTLPS 427
           L   +T+S   +   + +SR+ P           G G         S     +K QT P+
Sbjct: 300 LSGSKTNSPKNSVHKLDVSRSPPLMVKKNPAFNKGSGIVTNGSFSSSNAEGLEKTQTTPN 359

Query: 428 WKSSFRQPRSL--SGSPKGGGS----SLEVPIISSG--GN--------WLMNGLSSLRGH 471
                R+  SL  SG+  G  S    ++ + I++S   GN        WL NG  +LR +
Sbjct: 360 GSLQARRSSSLKVSGTKMGTHSVQNGTVRMGILNSDTLGNPTNVRNMSWLPNGYVTLRDN 419

Query: 472 RRASSGDRLKDSGSVQRLSTYDNVPAPGLVPGI---PSVASMAWSGASSSESSVGGSLSS 528
           ++      L   G   RLSTYDNV     +  +    S+ S  WS  SS E S+  + +S
Sbjct: 420 KQKEQAGEL---GQHNRLSTYDNVHQQFSMMNLDDKQSIDSATWS-TSSCEISLPENSNS 475

Query: 529 C----TACRASDSSARSSLHTDWALEPSPLPSSSEDPKSLDLDHSMDEAGAGASNSEPSE 584
           C    T C   D    +    D  L+  P    S  P+  +        G  +S +  S 
Sbjct: 476 CRSSTTTCPEQDFFGGN--FEDPVLDGPPQDDLSH-PRDYESKSDHRSVGGRSSRATSSS 532

Query: 585 PDSPT--REHARRSEALQGLVTELRAELCRQRTEYERSVKRIEEGSADLRKRMSRLEEEL 642
            +S T     +    AL  LV+ L+ E+ +Q+ EYE  +K +E+ +  L   M  L +EL
Sbjct: 533 DNSETFVGNSSSNHSALHSLVSSLKQEMTKQKIEYESRIKSLEQRNLTLETEMMSLHDEL 592

Query: 643 DQEKKKYIMLEIKLRNSERAREDAERRNQLLQREMEEFFSTLGSLTV 689
           DQE+KK+ M+EIK+RN+ERA+EDAE+RN +LQ+EME+FFST G LTV
Sbjct: 593 DQERKKFTMIEIKMRNAERAKEDAEKRNDMLQKEMEQFFSTFGELTV 639


>gi|55770898 Rho GTPase activating protein 25 isoform a [Homo
           sapiens]
          Length = 645

 Score =  466 bits (1199), Expect = e-131
 Identities = 287/694 (41%), Positives = 389/694 (56%), Gaps = 83/694 (11%)

Query: 5   KIRQARRARSKSLVMGEQSRSPGRMPCPHRLGPVLKAGWLKKQRSIMKNWQQRWFVLRGD 64
           K+  A+ ARS+S++ GEQ  +      P+ L   +K GWLKKQRSI+KNWQQR+FVLR  
Sbjct: 14  KVEAAKIARSRSVMTGEQMAAFHPSSTPNPLERPIKMGWLKKQRSIVKNWQQRYFVLRAQ 73

Query: 65  QLFYYKDKDEIKPQGFISLQGTQVTELPPGPEDPGKHLFEISPGGAGEREKVPANPEALL 124
           QL+YYKD+++ KPQG + L G  + E+   PE+ GK +FEI P    +        ++ +
Sbjct: 74  QLYYYKDEEDTKPQGCMYLPGCTIKEIATNPEEAGKFVFEIIPASWDQNRM---GQDSYV 130

Query: 125 LMASSQRDMEDWVQAIRRVIWAPLGGGIFGQRLEETVHHERKYGPRLAPLLVEQCVDFIR 184
           LMASSQ +ME+WV+ +RRV   P G  +FGQRL+ETV +E+K+GP L P+LVE+C +FI 
Sbjct: 131 LMASSQAEMEEWVKFLRRVAGTPCG--VFGQRLDETVAYEQKFGPHLVPILVEKCAEFIL 188

Query: 185 ERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASLLKLYLRELPEPVVP 244
           E G  EEG+FR+PGQ NLV+ L+D+FD GE+P FD  TDVHTVASLLKLYLR+LPEPVVP
Sbjct: 189 EHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPEPVVP 248

Query: 245 FARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKFLDEVQAYSNVNKMS 304
           +++YE FL C QL   DE +   EL KQ+S LP+ NY+LL YIC+FL E+Q    VNKMS
Sbjct: 249 WSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFLHEIQLNCAVNKMS 308

Query: 305 VQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIRKHSQLF--TAPVPEGPTSPRG 362
           V NLATV G N++R +VEDP  IM GT  +Q +MT++IR H  LF  +  +P  P + + 
Sbjct: 309 VDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDIPLSPPAQKN 368

Query: 363 G------LQCAVGWGSEEVTRDSQGEPGGPGLPAHRTSSLDG-----AAVAVLSRTAPTG 411
                   + +VGW + E  R S+ +          T+S  G     A     S+     
Sbjct: 369 DPKKAPVARSSVGWDATEDLRISRTDSFSSMTSDSDTTSPTGQQPSDAFPEDSSKVPREK 428

Query: 412 PGS-RCSPGKKVQTLPSWKSSFRQPRSLSGSPKGGGSSLEVPIISSGGNWLMNGLSSLRG 470
           PG  +    K+ QTLP+ K           S   G +S ++ I  +      +   +  G
Sbjct: 429 PGDWKMQSRKRTQTLPNRKCFLT-------SAFQGANSSKMEIFKNEFWSPSSEAKAGEG 481

Query: 471 HRRASSGDRLKDSGSVQRLSTYDNVPAPGLVPGIPSVASMAWSGASSSESSVGGSLSSCT 530
           HRR  S D L+     QR STYDNVP+   +PG P                         
Sbjct: 482 HRRTMSQD-LRQLSDSQRTSTYDNVPS---LPGSPGE----------------------- 514

Query: 531 ACRASDSSARSSLHTDWALEPSPLPSSSEDPKSLDLDHSMDEAGAGASNSEPSEPDSPTR 590
                              E S L S + D K   L     E G G  NS   E DS   
Sbjct: 515 -------------------EASALSSQACDSKGDTLASPNSETGPGKKNSGEEEIDS--- 552

Query: 591 EHARRSEALQGLVTELRAELCRQRTEYERSVKRIEEGSADLRKRMSRLEEELDQEKKKYI 650
                   LQ +V ELR E+  Q+  YE  +K +E+ + D+  ++ RL EEL++EKKK  
Sbjct: 553 --------LQRMVQELRKEIETQKQMYEEQIKNLEKENYDVWAKVVRLNEELEKEKKKSA 604

Query: 651 MLEIKLRNSERAREDAERRNQLLQREMEEFFSTL 684
            LEI LRN ER+RED E+RN+ L+ E++EF  ++
Sbjct: 605 ALEISLRNMERSREDVEKRNKALEEEVKEFVKSM 638


>gi|7661882 Rho GTPase activating protein 25 isoform b [Homo
           sapiens]
          Length = 638

 Score =  462 bits (1189), Expect = e-130
 Identities = 285/687 (41%), Positives = 385/687 (56%), Gaps = 83/687 (12%)

Query: 12  ARSKSLVMGEQSRSPGRMPCPHRLGPVLKAGWLKKQRSIMKNWQQRWFVLRGDQLFYYKD 71
           ARS+S++ GEQ  +      P+ L   +K GWLKKQRSI+KNWQQR+FVLR  QL+YYKD
Sbjct: 14  ARSRSVMTGEQMAAFHPSSTPNPLERPIKMGWLKKQRSIVKNWQQRYFVLRAQQLYYYKD 73

Query: 72  KDEIKPQGFISLQGTQVTELPPGPEDPGKHLFEISPGGAGEREKVPANPEALLLMASSQR 131
           +++ KPQG + L G  + E+   PE+ GK +FEI P    +        ++ +LMASSQ 
Sbjct: 74  EEDTKPQGCMYLPGCTIKEIATNPEEAGKFVFEIIPASWDQNRM---GQDSYVLMASSQA 130

Query: 132 DMEDWVQAIRRVIWAPLGGGIFGQRLEETVHHERKYGPRLAPLLVEQCVDFIRERGLTEE 191
           +ME+WV+ +RRV   P G  +FGQRL+ETV +E+K+GP L P+LVE+C +FI E G  EE
Sbjct: 131 EMEEWVKFLRRVAGTPCG--VFGQRLDETVAYEQKFGPHLVPILVEKCAEFILEHGRNEE 188

Query: 192 GLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASLLKLYLRELPEPVVPFARYEDF 251
           G+FR+PGQ NLV+ L+D+FD GE+P FD  TDVHTVASLLKLYLR+LPEPVVP+++YE F
Sbjct: 189 GIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPEPVVPWSQYEGF 248

Query: 252 LSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKFLDEVQAYSNVNKMSVQNLATV 311
           L C QL   DE +   EL KQ+S LP+ NY+LL YIC+FL E+Q    VNKMSV NLATV
Sbjct: 249 LLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFLHEIQLNCAVNKMSVDNLATV 308

Query: 312 FGPNILRPQVEDPVTIMEGTSLVQHLMTVLIRKHSQLF--TAPVPEGPTSPRGG------ 363
            G N++R +VEDP  IM GT  +Q +MT++IR H  LF  +  +P  P + +        
Sbjct: 309 IGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDIPLSPPAQKNDPKKAPV 368

Query: 364 LQCAVGWGSEEVTRDSQGEPGGPGLPAHRTSSLDG-----AAVAVLSRTAPTGPGS-RCS 417
            + +VGW + E  R S+ +          T+S  G     A     S+     PG  +  
Sbjct: 369 ARSSVGWDATEDLRISRTDSFSSMTSDSDTTSPTGQQPSDAFPEDSSKVPREKPGDWKMQ 428

Query: 418 PGKKVQTLPSWKSSFRQPRSLSGSPKGGGSSLEVPIISSGGNWLMNGLSSLRGHRRASSG 477
             K+ QTLP+ K           S   G +S ++ I  +      +   +  GHRR  S 
Sbjct: 429 SRKRTQTLPNRKCFLT-------SAFQGANSSKMEIFKNEFWSPSSEAKAGEGHRRTMSQ 481

Query: 478 DRLKDSGSVQRLSTYDNVPAPGLVPGIPSVASMAWSGASSSESSVGGSLSSCTACRASDS 537
           D L+     QR STYDNVP+   +PG P                                
Sbjct: 482 D-LRQLSDSQRTSTYDNVPS---LPGSPGE------------------------------ 507

Query: 538 SARSSLHTDWALEPSPLPSSSEDPKSLDLDHSMDEAGAGASNSEPSEPDSPTREHARRSE 597
                       E S L S + D K   L     E G G  NS   E DS          
Sbjct: 508 ------------EASALSSQACDSKGDTLASPNSETGPGKKNSGEEEIDS---------- 545

Query: 598 ALQGLVTELRAELCRQRTEYERSVKRIEEGSADLRKRMSRLEEELDQEKKKYIMLEIKLR 657
            LQ +V ELR E+  Q+  YE  +K +E+ + D+  ++ RL EEL++EKKK   LEI LR
Sbjct: 546 -LQRMVQELRKEIETQKQMYEEQIKNLEKENYDVWAKVVRLNEELEKEKKKSAALEISLR 604

Query: 658 NSERAREDAERRNQLLQREMEEFFSTL 684
           N ER+RED E+RN+ L+ E++EF  ++
Sbjct: 605 NMERSREDVEKRNKALEEEVKEFVKSM 631


>gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo
           sapiens]
          Length = 655

 Score =  438 bits (1126), Expect = e-123
 Identities = 278/614 (45%), Positives = 362/614 (58%), Gaps = 85/614 (13%)

Query: 151 GIFGQRLEETVHHERKYGPRLAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSF 210
           GIFGQ+LE+TV +E++YG RLAP+LVEQCVDFIR+RGL EEGLFR+PGQANLV++LQD+F
Sbjct: 38  GIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAF 97

Query: 211 DCGEKPLFDSTTDVHTVASLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELA 270
           DCGEKP FDS TDVHTVASLLKLYLRELPEPV+P+A+YEDFLSCA+LL+K+E  G  ELA
Sbjct: 98  DCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELA 157

Query: 271 KQVSNLPQANYNLLRYICKFLDEVQAYSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEG 330
           KQV +LP  NYNLL+YIC+FLDEVQ+YS VNKMSVQNLATVFGPNILRP+VEDP+TIMEG
Sbjct: 158 KQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEG 217

Query: 331 TSLVQHLMTVLIRKHSQLFTAPVPEGPTSPRGGL-------------------------- 364
           T +VQ LM+V+I KH  LF     E  + P+ G+                          
Sbjct: 218 TVVVQQLMSVMISKHDCLFPKDA-ELQSKPQDGVSNNNEIQKKATMGQLQNKENNNTKDS 276

Query: 365 ---QCAVGWGSEEVTRDSQGEPGGP-GLPAHRTSSLDGAAVAV-LSRTAP---------- 409
              QC+  W   E  + S    G P  L   +T+S   +   + +SR+ P          
Sbjct: 277 PSRQCS--WDKSESPQRSSMNNGSPTALSGSKTNSPKNSVHKLDVSRSPPLMVKKNPAFN 334

Query: 410 TGPG---------SRCSPGKKVQTLPSWKSSFRQPRSL--SGSPKGGGS----SLEVPII 454
            G G         S     +K QT P+     R+  SL  SG+  G  S    ++ + I+
Sbjct: 335 KGSGIVTNGSFSSSNAEGLEKTQTTPNGSLQARRSSSLKVSGTKMGTHSVQNGTVRMGIL 394

Query: 455 SSG--GN--------WLMNGLSSLRGHRRASSGDRLKDSGSVQRLSTYDNVPAPGLVPGI 504
           +S   GN        WL NG  +LR +++      L   G   RLSTYDNV     +  +
Sbjct: 395 NSDTLGNPTNVRNMSWLPNGYVTLRDNKQKEQAGEL---GQHNRLSTYDNVHQQFSMMNL 451

Query: 505 ---PSVASMAWSGASSSESSVGGSLSSC----TACRASDSSARSSLHTDWALEPSPLPSS 557
               S+ S  WS  SS E S+  + +SC    T C   D    +    D  L+  P    
Sbjct: 452 DDKQSIDSATWS-TSSCEISLPENSNSCRSSTTTCPEQDFFGGN--FEDPVLDGPPQDDL 508

Query: 558 SEDPKSLDLDHSMDEAGAGASNSEPSEPDSPT--REHARRSEALQGLVTELRAELCRQRT 615
           S  P+  +        G  +S +  S  +S T     +    AL  LV+ L+ E+ +Q+ 
Sbjct: 509 SH-PRDYESKSDHRSVGGRSSRATSSSDNSETFVGNSSSNHSALHSLVSSLKQEMTKQKI 567

Query: 616 EYERSVKRIEEGSADLRKRMSRLEEELDQEKKKYIMLEIKLRNSERAREDAERRNQLLQR 675
           EYE  +K +E+ +  L   M  L +ELDQE+KK+ M+EIK+RN+ERA+EDAE+RN +LQ+
Sbjct: 568 EYESRIKSLEQRNLTLETEMMSLHDELDQERKKFTMIEIKMRNAERAKEDAEKRNDMLQK 627

Query: 676 EMEEFFSTLGSLTV 689
           EME+FFST G LTV
Sbjct: 628 EMEQFFSTFGELTV 641


>gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]
          Length = 818

 Score =  120 bits (301), Expect = 4e-27
 Identities = 70/183 (38%), Positives = 107/183 (58%), Gaps = 6/183 (3%)

Query: 153 FGQRLEETVHHERKYGPRLAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDC 212
           FG+ LEE   H    G  +A   +E CV  + E G+ EEGLFR+   A+ ++ L+ + DC
Sbjct: 253 FGKPLEE---HLTISGREIA-FPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDC 308

Query: 213 GEKPLFDSTTDVHTVASLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQ 272
               + + + D H +A  LK YLRELPEP++ F  Y++++  + +  +D+    L  A  
Sbjct: 309 CVVDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNA-- 366

Query: 273 VSNLPQANYNLLRYICKFLDEVQAYSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTS 332
              LP+AN+N +RY+ KFL ++  Y +VNKM+  N+A V GPN+L PQ E  +T M  T 
Sbjct: 367 CEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEMMTTV 426

Query: 333 LVQ 335
            +Q
Sbjct: 427 SLQ 429


>gi|75677374 SLIT-ROBO Rho GTPase activating protein 3 isoform b
           [Homo sapiens]
          Length = 1075

 Score =  117 bits (292), Expect = 5e-26
 Identities = 80/271 (29%), Positives = 135/271 (49%), Gaps = 30/271 (11%)

Query: 173 PLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFD--STTDVHTVASL 230
           PL+VE C+ +I   GL ++G+FR+PG    V D+++SF+ GE PL D  +  D+++VA +
Sbjct: 496 PLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKNSFERGEDPLVDDQNERDINSVAGV 555

Query: 231 LKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKF 290
           LKLY R L  P+ P  R++D +S  +L  ++  E   ++ + +  LP+    ++RY+  F
Sbjct: 556 LKLYFRGLENPLFPKERFQDLISTIKL--ENPAERVHQIQQILVTLPRVVIVVMRYLFAF 613

Query: 291 LDEVQAYSNVNKMSVQNLATVFGPNILR-PQVEDPVTIMEGTSLVQHLMTVLIRKHSQLF 349
           L+ +  YS+ N M   NLA  FGP ++  P  +DPV+     + +  ++  +I  H  +F
Sbjct: 614 LNHLSQYSDENMMDPYNLAICFGPTLMHIPDGQDPVSCQ---AHINEVIKTIIIHHEAIF 670

Query: 350 TAPVP-EGPTSPRGGLQCAVGWGSEEVTRDSQGEPGGPGLPAHRTSSLDGAAVAVLSRTA 408
            +P   EGP   +    C    G EE       EPG               A+  +    
Sbjct: 671 PSPRELEGPVYEK----CMA--GGEEYCDSPHSEPG---------------AIDEVDHDN 709

Query: 409 PTGPGSRCSPGKKVQTLPSWKSSFRQPRSLS 439
            T P +     ++++ +  +    R PR LS
Sbjct: 710 GTEPHTSDEEVEQIEAIAKFDYMGRSPRELS 740


>gi|24307967 SLIT-ROBO Rho GTPase activating protein 3 isoform a
           [Homo sapiens]
          Length = 1099

 Score =  117 bits (292), Expect = 5e-26
 Identities = 80/271 (29%), Positives = 135/271 (49%), Gaps = 30/271 (11%)

Query: 173 PLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFD--STTDVHTVASL 230
           PL+VE C+ +I   GL ++G+FR+PG    V D+++SF+ GE PL D  +  D+++VA +
Sbjct: 520 PLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKNSFERGEDPLVDDQNERDINSVAGV 579

Query: 231 LKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKF 290
           LKLY R L  P+ P  R++D +S  +L  ++  E   ++ + +  LP+    ++RY+  F
Sbjct: 580 LKLYFRGLENPLFPKERFQDLISTIKL--ENPAERVHQIQQILVTLPRVVIVVMRYLFAF 637

Query: 291 LDEVQAYSNVNKMSVQNLATVFGPNILR-PQVEDPVTIMEGTSLVQHLMTVLIRKHSQLF 349
           L+ +  YS+ N M   NLA  FGP ++  P  +DPV+     + +  ++  +I  H  +F
Sbjct: 638 LNHLSQYSDENMMDPYNLAICFGPTLMHIPDGQDPVSCQ---AHINEVIKTIIIHHEAIF 694

Query: 350 TAPVP-EGPTSPRGGLQCAVGWGSEEVTRDSQGEPGGPGLPAHRTSSLDGAAVAVLSRTA 408
            +P   EGP   +    C    G EE       EPG               A+  +    
Sbjct: 695 PSPRELEGPVYEK----CMA--GGEEYCDSPHSEPG---------------AIDEVDHDN 733

Query: 409 PTGPGSRCSPGKKVQTLPSWKSSFRQPRSLS 439
            T P +     ++++ +  +    R PR LS
Sbjct: 734 GTEPHTSDEEVEQIEAIAKFDYMGRSPRELS 764


>gi|44917604 SLIT-ROBO Rho GTPase activating protein 1 [Homo
           sapiens]
          Length = 1085

 Score =  114 bits (286), Expect = 2e-25
 Identities = 75/225 (33%), Positives = 122/225 (54%), Gaps = 16/225 (7%)

Query: 170 RLAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFD--STTDVHTV 227
           ++ PL+VE C+ FI   GL  +G+FR+ G    V D+++SF+ GE PL D  S  D+++V
Sbjct: 517 QVIPLIVESCIRFINLYGLQHQGIFRVSGSQVEVNDIKNSFERGENPLADDQSNHDINSV 576

Query: 228 ASLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYI 287
           A +LKLY R L  P+ P  R+ D +SC ++   +  E  L + K +  LP++   ++RY+
Sbjct: 577 AGVLKLYFRGLENPLFPKERFNDLISCIRI--DNLYERALHIRKLLLTLPRSVLIVMRYL 634

Query: 288 CKFLDEVQAYSNVNKMSVQNLATVFGPNILR-PQVEDPVTIMEGTSLVQHLMTVLIRKHS 346
             FL+ +  YS+ N M   NLA  FGP ++  P+++D V+     + V  ++  +I  H 
Sbjct: 635 FAFLNHLSQYSDENMMDPYNLAICFGPTLMPVPEIQDQVSCQ---AHVNEIIKTIIIHHE 691

Query: 347 QLF-TAPVPEGPTSPR---GGLQCAVGWGS----EEVTRDSQGEP 383
            +F  A   +GP   +   G   C   +      EEV +D+  EP
Sbjct: 692 TIFPDAKELDGPVYEKCMAGDDYCDSPYSEHGTLEEVDQDAGTEP 736


>gi|54860079 nadrin isoform 1 [Homo sapiens]
          Length = 881

 Score =  114 bits (285), Expect = 3e-25
 Identities = 73/199 (36%), Positives = 113/199 (56%), Gaps = 9/199 (4%)

Query: 153 FGQRLEETVHHERKYGPRLAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDC 212
           FG  LEE   H ++ G  +A L +E CV  + E G+ EEGLFR+   A+ ++ L+ + DC
Sbjct: 250 FGTPLEE---HLKRSGREIA-LPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDC 305

Query: 213 GEKPLFDSTTDVHTVASLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQ 272
               L +  +D H VA  LK YLRELPEP++ F  YE++   A +  +D+ +   +L + 
Sbjct: 306 STSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASV--QDQDKKLQDLWRT 363

Query: 273 VSNLPQANYNLLRYICKFLDEVQAYSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTS 332
              LP  N+   RY+ KFL ++   S+VNKM+  N+A V GPN+L  + E  +  M   +
Sbjct: 364 CQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWARNEGTLAEMAAAT 423

Query: 333 LVQHLMTVL--IRKHSQLF 349
            V H++ V+  I +H+  F
Sbjct: 424 SV-HVVAVIEPIIQHADWF 441


>gi|54860105 nadrin isoform 2 [Homo sapiens]
          Length = 803

 Score =  114 bits (285), Expect = 3e-25
 Identities = 73/199 (36%), Positives = 113/199 (56%), Gaps = 9/199 (4%)

Query: 153 FGQRLEETVHHERKYGPRLAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDC 212
           FG  LEE   H ++ G  +A L +E CV  + E G+ EEGLFR+   A+ ++ L+ + DC
Sbjct: 250 FGTPLEE---HLKRSGREIA-LPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDC 305

Query: 213 GEKPLFDSTTDVHTVASLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQ 272
               L +  +D H VA  LK YLRELPEP++ F  YE++   A +  +D+ +   +L + 
Sbjct: 306 STSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASV--QDQDKKLQDLWRT 363

Query: 273 VSNLPQANYNLLRYICKFLDEVQAYSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTS 332
              LP  N+   RY+ KFL ++   S+VNKM+  N+A V GPN+L  + E  +  M   +
Sbjct: 364 CQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWARNEGTLAEMAAAT 423

Query: 333 LVQHLMTVL--IRKHSQLF 349
            V H++ V+  I +H+  F
Sbjct: 424 SV-HVVAVIEPIIQHADWF 441


>gi|4757766 Rho GTPase activating protein 1 [Homo sapiens]
          Length = 439

 Score =  112 bits (280), Expect = 1e-24
 Identities = 65/210 (30%), Positives = 108/210 (51%), Gaps = 7/210 (3%)

Query: 147 PLGGGIFGQRLEETVHHERKYGPRLAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDL 206
           PL    FG  L+       +  P   P+++ + V +++   LT EG+FR      +VR++
Sbjct: 236 PLPNQQFGVSLQHLQEKNPEQEP--IPIVLRETVAYLQAHALTTEGIFRRSANTQVVREV 293

Query: 207 QDSFDCGEKPLFDSTTDVHTVASLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGT 266
           Q  ++ G    FD   ++H  A +LK +LRELPEP++ F  Y   +     L  DE +  
Sbjct: 294 QQKYNMGLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVG---FLNIDESQRV 350

Query: 267 LELAKQVSNLPQANYNLLRYICKFLDEVQAYSNVNKMSVQNLATVFGPNILRPQVEDPVT 326
               + +  LP+ NY +LR++  FL ++ A+S+ NKM+  NLA VFGPN+L    +D   
Sbjct: 351 PATLQVLQTLPEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLL--WAKDAAI 408

Query: 327 IMEGTSLVQHLMTVLIRKHSQLFTAPVPEG 356
            ++  + +      L+    +LF +P P G
Sbjct: 409 TLKAINPINTFTKFLLDHQGELFPSPDPSG 438


>gi|112363100 SLIT-ROBO Rho GTPase activating protein 2 isoform a
           [Homo sapiens]
          Length = 1071

 Score =  109 bits (273), Expect = 8e-24
 Identities = 66/195 (33%), Positives = 106/195 (54%), Gaps = 9/195 (4%)

Query: 173 PLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLF--DSTTDVHTVASL 230
           PL+VE C+ FI   GL  EG+FR+ G    V D++++F+ GE PL    +  D+ ++A +
Sbjct: 505 PLVVESCIRFISRHGLQHEGIFRVSGSQVEVNDIKNAFERGEDPLAGDQNDHDMDSIAGV 564

Query: 231 LKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKF 290
           LKLY R L  P+ P   + D ++C  +   +  E  L + K +  LP+    ++RY+  F
Sbjct: 565 LKLYFRGLEHPLFPKDIFHDLMACVTM--DNLQERALHIRKVLLVLPKTTLIIMRYLFAF 622

Query: 291 LDEVQAYSNVNKMSVQNLATVFGPNILR-PQVEDPVTIMEGTSLVQHLMTVLIRKHSQLF 349
           L+ +  +S  N M   NLA  FGP+++  P+  D V+     + V  L+  +I +H  +F
Sbjct: 623 LNHLSQFSEENMMDPYNLAICFGPSLMSVPEGHDQVSCQ---AHVNELIKTIIIQHENIF 679

Query: 350 TAPVP-EGPTSPRGG 363
            +P   EGP   RGG
Sbjct: 680 PSPRELEGPVYSRGG 694


>gi|112363096 SLIT-ROBO Rho GTPase activating protein 2 isoform b
           [Homo sapiens]
          Length = 836

 Score =  109 bits (273), Expect = 8e-24
 Identities = 66/195 (33%), Positives = 106/195 (54%), Gaps = 9/195 (4%)

Query: 173 PLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLF--DSTTDVHTVASL 230
           PL+VE C+ FI   GL  EG+FR+ G    V D++++F+ GE PL    +  D+ ++A +
Sbjct: 505 PLVVESCIRFISRHGLQHEGIFRVSGSQVEVNDIKNAFERGEDPLAGDQNDHDMDSIAGV 564

Query: 231 LKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKF 290
           LKLY R L  P+ P   + D ++C  +   +  E  L + K +  LP+    ++RY+  F
Sbjct: 565 LKLYFRGLEHPLFPKDIFHDLMACVTM--DNLQERALHIRKVLLVLPKTTLIIMRYLFAF 622

Query: 291 LDEVQAYSNVNKMSVQNLATVFGPNILR-PQVEDPVTIMEGTSLVQHLMTVLIRKHSQLF 349
           L+ +  +S  N M   NLA  FGP+++  P+  D V+     + V  L+  +I +H  +F
Sbjct: 623 LNHLSQFSEENMMDPYNLAICFGPSLMSVPEGHDQVSCQ---AHVNELIKTIIIQHENIF 679

Query: 350 TAPVP-EGPTSPRGG 363
            +P   EGP   RGG
Sbjct: 680 PSPRELEGPVYSRGG 694


>gi|226693398 Rho GTPase activating protein 27 isoform b [Homo
           sapiens]
          Length = 521

 Score =  108 bits (269), Expect = 2e-23
 Identities = 67/193 (34%), Positives = 105/193 (54%), Gaps = 10/193 (5%)

Query: 152 IFGQRLEETVHHERKYGPRLAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFD 211
           +FG  L      ER   PR     V+QC+  +  RGL  +GL+R+ G    ++ L+   D
Sbjct: 326 VFGCALAALCERERSRVPRF----VQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKVD 381

Query: 212 CGEKPLFDSTT--DVHTVASLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLEL 269
             E+   D     DVH +   LKL+ RELPEP+ PF+ +  F++  +L  +D+   +  +
Sbjct: 382 HDERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFRQFIAAIKL--QDQARRSRCV 439

Query: 270 AKQVSNLPQANYNLLRYICKFLDEVQAYSNVNKMSVQNLATVFGPNILRPQVEDPVTIME 329
              V +LP  N++ LR + + L  V  +   N+MSVQ++A VFGP +LRP+VE+  T M 
Sbjct: 440 RDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTLLRPEVEE--TSMP 497

Query: 330 GTSLVQHLMTVLI 342
            T + Q+ +  LI
Sbjct: 498 MTMVFQNQVVELI 510


>gi|40548322 Rho GTPase activating protein 27 isoform a [Homo
           sapiens]
          Length = 548

 Score =  108 bits (269), Expect = 2e-23
 Identities = 67/193 (34%), Positives = 105/193 (54%), Gaps = 10/193 (5%)

Query: 152 IFGQRLEETVHHERKYGPRLAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFD 211
           +FG  L      ER   PR     V+QC+  +  RGL  +GL+R+ G    ++ L+   D
Sbjct: 353 VFGCALAALCERERSRVPRF----VQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKVD 408

Query: 212 CGEKPLFDSTT--DVHTVASLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLEL 269
             E+   D     DVH +   LKL+ RELPEP+ PF+ +  F++  +L  +D+   +  +
Sbjct: 409 HDERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFRQFIAAIKL--QDQARRSRCV 466

Query: 270 AKQVSNLPQANYNLLRYICKFLDEVQAYSNVNKMSVQNLATVFGPNILRPQVEDPVTIME 329
              V +LP  N++ LR + + L  V  +   N+MSVQ++A VFGP +LRP+VE+  T M 
Sbjct: 467 RDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTLLRPEVEE--TSMP 524

Query: 330 GTSLVQHLMTVLI 342
            T + Q+ +  LI
Sbjct: 525 MTMVFQNQVVELI 537


>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
          Length = 701

 Score =  106 bits (265), Expect = 6e-23
 Identities = 126/463 (27%), Positives = 180/463 (38%), Gaps = 67/463 (14%)

Query: 162 HHERKYGPRLAPLL----------VEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFD 211
           H  R YG  LA  L          +E CV  +   G+ EEGLFR+   A++++ L+ +  
Sbjct: 269 HFPRVYGVSLATHLQELGREIALPIEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMA 328

Query: 212 CGEKPLFDSTTDVHTVASLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAK 271
                L +  +D H VA  LK YLRELPEP++ F  Y+D++  A L  K+ G     L +
Sbjct: 329 SDPHSLEEFCSDPHAVAGALKSYLRELPEPLMTFDLYDDWMRAASL--KEPGARLQALQE 386

Query: 272 QVSNLPQANYNLLRYICKFLDEVQAYSNVNKMSVQNLATVFGPNIL-RPQVEDPVTIMEG 330
             S LP  N + LRY+ KFL  +     VNKM+  N+A V GPN+L  P+ E     ++ 
Sbjct: 387 VCSRLPPENLSNLRYLMKFLARLAEEQEVNKMTPSNIAIVLGPNLLWPPEKEGDQAQLDA 446

Query: 331 TSL----VQHLMTVLIRKHSQLFTAPVPEGPTSPRGGLQCAV--------GWGSEEVTRD 378
            S+    V  ++  LI+    LF   +    +    GL  AV           SEE+   
Sbjct: 447 ASVSSIQVVGVVEALIQSADTLFPGDINFNVS----GLFSAVTLQDTVSDRLASEELPST 502

Query: 379 SQGEPGGPGLPAHRTSSLDG---AAVAVLSRTAPTGPGSRCSPGKKVQTLPSWKSSFRQP 435
           +   P     PA   +       A+ A   RT    P    SP K  ++ P   +     
Sbjct: 503 AVPTPATTPAPAPAPAPAPAPALASAATKERTESEVPPRPASP-KVTRSPPETAAPVEDM 561

Query: 436 RSLSGSPKGGGSSLEVPIISSGGNWLMNGLSSLRGHRRASSGDRL-KDSGSVQRLSTYDN 494
              +  P     ++  P +S              G R +     L   SGS         
Sbjct: 562 ARRTKRPAPARPTMPPPQVS--------------GSRSSPPAPPLPPGSGS--------- 598

Query: 495 VPAPGLVPGIPSVASMAWSGASSSESSVGGSLSSCTACRASDSSARSSLHTDWAL--EPS 552
                  PG P        G+S    +V   L       A   S RS      A     S
Sbjct: 599 -------PGTPQALPRRLVGSSLRAPTVPPPLPPTPPQPARRQSRRSPASPSPASPGPAS 651

Query: 553 PLPSSSEDPKSLDLDHSMDEAGA-GASNSEPSEPDSPTREHAR 594
           P P S  +P  +DL  +  E GA  A +  P+ P  P +   R
Sbjct: 652 PSPVSLSNPAQVDLGAATAEGGAPEAISGVPTPPAIPPQPRPR 694


>gi|56119110 family with sequence similarity 13, member A1 isoform a
           [Homo sapiens]
          Length = 1023

 Score =  105 bits (263), Expect = 1e-22
 Identities = 64/183 (34%), Positives = 97/183 (53%), Gaps = 4/183 (2%)

Query: 173 PLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASLLK 232
           P +V   V+++ + GLT+EGLFR+ G   +V  L+  F+ G         DV + ASLLK
Sbjct: 59  PAVVWNIVEYLTQHGLTQEGLFRVNGNVKVVEQLRLKFESGVPVELGKDGDVCSAASLLK 118

Query: 233 LYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKFLD 292
           L+LRELP+ ++  A    F+   Q    D  E +L     +  LP  +Y LL+Y+C+FL 
Sbjct: 119 LFLRELPDSLITSALQPRFIQLFQDGRNDVQESSLR--DLIKELPDTHYCLLKYLCQFLT 176

Query: 293 EVQAYSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIRKHSQLFTAP 352
           +V  +   N+M+V NLATVFGPN     V   +  M+   L   +M  ++  ++ LF   
Sbjct: 177 KVAKHHVQNRMNVHNLATVFGPNCF--HVPPGLEGMKEQDLCNKIMAKILENYNTLFEVE 234

Query: 353 VPE 355
             E
Sbjct: 235 YTE 237


>gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]
          Length = 1958

 Score =  103 bits (258), Expect = 4e-22
 Identities = 77/242 (31%), Positives = 120/242 (49%), Gaps = 22/242 (9%)

Query: 147  PLGGGIFGQRLEETVH-HERKYGPRLAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRD 205
            P   G FG RL++    H  +Y     PL+V+ C   + ERGL   G++R+PG    +  
Sbjct: 1139 PTATGTFGVRLDDCPPAHTNRY----IPLIVDICCKLVEERGLEYTGIYRVPGNNAAISS 1194

Query: 206  LQDSFDCGEKPLF---DSTTDVHTVASLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDE 262
            +Q+  + G   +    D   D++ ++SLLK + R+LPEP+    +Y DF+   +   +D 
Sbjct: 1195 MQEELNKGMADIDIQDDKWRDLNVISSLLKSFFRKLPEPLFTNDKYADFIEANR--KEDP 1252

Query: 263  GEGTLELAKQVSNLPQANYNLLRYICKFLDEVQAYSNVNKMSVQNLATVFGPNILRPQVE 322
             +    L + + +LP+ +Y  L+++   L  V   S  NKM  +NLA VFGP ++R   E
Sbjct: 1253 LDRLKTLKRLIHDLPEHHYETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTS-E 1311

Query: 323  DPVTIMEGTSLVQH-LMTVLIRKHSQLFTAPVPEGPTSPRGGLQCAVGWGSEEVTRDSQG 381
            D +T M      Q+ ++  LI+ H   FT    EG   P   +Q       EE T DSQ 
Sbjct: 1312 DNMTHMVTHMPDQYKIVETLIQHHDWFFT---EEGAEEPLTTVQ-------EESTVDSQP 1361

Query: 382  EP 383
             P
Sbjct: 1362 VP 1363



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 17/45 (37%), Positives = 23/45 (51%), Gaps = 10/45 (22%)

Query: 40  KAGWL----------KKQRSIMKNWQQRWFVLRGDQLFYYKDKDE 74
           K GWL          K+    ++ W+Q + VLRG  L+ YKDK E
Sbjct: 934 KEGWLHFRPLVTDKGKRVGGSIRPWKQMYVVLRGHSLYLYKDKRE 978


>gi|226423858 PRR5-ARHGAP8 fusion protein [Homo sapiens]
          Length = 555

 Score =  103 bits (256), Expect = 7e-22
 Identities = 62/186 (33%), Positives = 98/186 (52%), Gaps = 5/186 (2%)

Query: 171 LAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASL 230
           L P ++   V ++RE+GL  EGLFR       VR++Q  ++ G+   FD   D+H  A +
Sbjct: 330 LIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVI 389

Query: 231 LKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKF 290
           LK +LRELP+P++ F  YE  L    + +     G  ++ +   +LP+ NY +LRY+  F
Sbjct: 390 LKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQILR---SLPEHNYVVLRYLMGF 446

Query: 291 LDEVQAYSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIRKHSQLFT 350
           L  V   S  NKM+  NLA VFG N++ P     V+ +     +     +LI  + ++F+
Sbjct: 447 LHAVSRESIFNKMNSSNLACVFGLNLIWP--SQGVSSLSALVPLNMFTELLIEYYEKIFS 504

Query: 351 APVPEG 356
            P   G
Sbjct: 505 TPEAPG 510


>gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens]
          Length = 1227

 Score =  103 bits (256), Expect = 7e-22
 Identities = 70/216 (32%), Positives = 104/216 (48%), Gaps = 17/216 (7%)

Query: 151  GIFGQRLEETVHHERKYGPRLAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSF 210
            G+FG ++      ER       P +V QCV+ I  RG+ E G++R+ G A  ++ L+ +F
Sbjct: 1006 GVFGVKIAVVTKRERSK----VPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAF 1061

Query: 211  DCGEKPL--FDSTTDVHTVASLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLE 268
            D   K +    S  DV+ +A  LKLY RELPEP+     Y +F     L      E  + 
Sbjct: 1062 DVNNKDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCM- 1120

Query: 269  LAKQVSNLPQANYNLLRYICKFLDEVQAYSNVNKMSVQNLATVFGPNILRPQVED----- 323
                + +LP+AN     ++   L  V     VNKMS+ NLATVFGP +LRP  ++     
Sbjct: 1121 -LNLLLSLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRPSEKESKLPA 1179

Query: 324  ----PVTIMEGTSLVQHLMTVLIRKHSQLFTAPVPE 355
                P+T+ +  SL       ++    QL   P P+
Sbjct: 1180 NPSQPITMTDSWSLEVMSQVQVLLYFLQLEAIPAPD 1215


>gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens]
          Length = 1271

 Score =  103 bits (256), Expect = 7e-22
 Identities = 70/216 (32%), Positives = 104/216 (48%), Gaps = 17/216 (7%)

Query: 151  GIFGQRLEETVHHERKYGPRLAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSF 210
            G+FG ++      ER       P +V QCV+ I  RG+ E G++R+ G A  ++ L+ +F
Sbjct: 1050 GVFGVKIAVVTKRERSK----VPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAF 1105

Query: 211  DCGEKPL--FDSTTDVHTVASLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLE 268
            D   K +    S  DV+ +A  LKLY RELPEP+     Y +F     L      E  + 
Sbjct: 1106 DVNNKDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCM- 1164

Query: 269  LAKQVSNLPQANYNLLRYICKFLDEVQAYSNVNKMSVQNLATVFGPNILRPQVED----- 323
                + +LP+AN     ++   L  V     VNKMS+ NLATVFGP +LRP  ++     
Sbjct: 1165 -LNLLLSLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRPSEKESKLPA 1223

Query: 324  ----PVTIMEGTSLVQHLMTVLIRKHSQLFTAPVPE 355
                P+T+ +  SL       ++    QL   P P+
Sbjct: 1224 NPSQPITMTDSWSLEVMSQVQVLLYFLQLEAIPAPD 1259


>gi|66346660 Rho GTPase activating protein 8 isoform 2 [Homo
           sapiens]
          Length = 433

 Score =  103 bits (256), Expect = 7e-22
 Identities = 62/186 (33%), Positives = 98/186 (52%), Gaps = 5/186 (2%)

Query: 171 LAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASL 230
           L P ++   V ++RE+GL  EGLFR       VR++Q  ++ G+   FD   D+H  A +
Sbjct: 208 LIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVI 267

Query: 231 LKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKF 290
           LK +LRELP+P++ F  YE  L    + +     G  ++ +   +LP+ NY +LRY+  F
Sbjct: 268 LKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQILR---SLPEHNYVVLRYLMGF 324

Query: 291 LDEVQAYSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIRKHSQLFT 350
           L  V   S  NKM+  NLA VFG N++ P     V+ +     +     +LI  + ++F+
Sbjct: 325 LHAVSRESIFNKMNSSNLACVFGLNLIWP--SQGVSSLSALVPLNMFTELLIEYYEKIFS 382

Query: 351 APVPEG 356
            P   G
Sbjct: 383 TPEAPG 388


>gi|66346662 Rho GTPase activating protein 8 isoform 1 [Homo
           sapiens]
          Length = 464

 Score =  103 bits (256), Expect = 7e-22
 Identities = 62/186 (33%), Positives = 98/186 (52%), Gaps = 5/186 (2%)

Query: 171 LAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASL 230
           L P ++   V ++RE+GL  EGLFR       VR++Q  ++ G+   FD   D+H  A +
Sbjct: 239 LIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVI 298

Query: 231 LKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKF 290
           LK +LRELP+P++ F  YE  L    + +     G  ++ +   +LP+ NY +LRY+  F
Sbjct: 299 LKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQILR---SLPEHNYVVLRYLMGF 355

Query: 291 LDEVQAYSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIRKHSQLFT 350
           L  V   S  NKM+  NLA VFG N++ P     V+ +     +     +LI  + ++F+
Sbjct: 356 LHAVSRESIFNKMNSSNLACVFGLNLIWP--SQGVSSLSALVPLNMFTELLIEYYEKIFS 413

Query: 351 APVPEG 356
            P   G
Sbjct: 414 TPEAPG 419


>gi|156071465 Rho GTPase activating protein 4 [Homo sapiens]
          Length = 946

 Score =  102 bits (254), Expect = 1e-21
 Identities = 71/190 (37%), Positives = 98/190 (51%), Gaps = 14/190 (7%)

Query: 173 PLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTT--DVHTVASL 230
           PL+VE C+ FI   GL  EG+FR+ G    V +++D+F+ GE PL +  T  D+ +VA +
Sbjct: 521 PLVVESCIRFINLNGLQHEGIFRVSGAQLRVSEIRDAFERGEDPLVEGCTAHDLDSVAGV 580

Query: 231 LKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVS----NLPQANYNLLRY 286
           LKLY R L  P+ P   +       +LL   E E T E  + VS     LP     +LRY
Sbjct: 581 LKLYFRSLEPPLFPPDLF------GELLASSELEATAERVEHVSRLLWRLPAPVLVVLRY 634

Query: 287 ICKFLDEVQAYSNVNKMSVQNLATVFGPNILR-PQVEDPVTIM-EGTSLVQHLMTVLIRK 344
           +  FL+ +  YS+ N M   NLA  FGP +L  P  +DPV +      LVQ L+    R 
Sbjct: 635 LFTFLNHLAQYSDENMMDPYNLAVCFGPTLLPVPAGQDPVALQGRVNQLVQTLIVQPDRV 694

Query: 345 HSQLFTAPVP 354
              L + P P
Sbjct: 695 FPPLTSLPGP 704



 Score = 31.6 bits (70), Expect = 2.6
 Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 1/84 (1%)

Query: 589 TREHARRSEAL-QGLVTELRAELCRQRTEYERSVKRIEEGSADLRKRMSRLEEELDQEKK 647
           TR+ +R S AL + L   L   L     +  R VK+  +    L+  +  +  EL   KK
Sbjct: 110 TRQQSRESAALSEVLAGPLAQRLSHIAEDVGRLVKKSRDLEQQLQDELLEVVSELQTAKK 169

Query: 648 KYIMLEIKLRNSERAREDAERRNQ 671
            Y    ++  N+E    +AER+ +
Sbjct: 170 TYQAYHMESVNAEAKLREAERQEE 193


>gi|91208437 GEM interacting protein [Homo sapiens]
          Length = 970

 Score =  101 bits (252), Expect = 2e-21
 Identities = 74/220 (33%), Positives = 105/220 (47%), Gaps = 24/220 (10%)

Query: 169 PRLAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVA 228
           P   P +V +C   I  R L  +G++R+ G    V  L  +F+ G   +  S    H V+
Sbjct: 561 PEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQAFENGRALVELSGNSPHDVS 620

Query: 229 SLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGE--GTLELAKQV--------SNLPQ 278
           S+LK +L+EL EPV+PF  Y+ F+S A+ L  D G+  GT   + +V          LP 
Sbjct: 621 SVLKRFLQELTEPVIPFHLYDAFISLAKTLHADPGDDPGTPSPSPEVIRSLKTLLVQLPD 680

Query: 279 ANYNLLRYICKFLDEVQAYSNVNKMSVQNLATVFGPNILRP------QVEDPVTIMEGTS 332
           +NYN LR++   L  V A    NKMS  NL  VFGP +LRP          PVT +  + 
Sbjct: 681 SNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLLRPPDGPRAASAIPVTCLLDSG 740

Query: 333 LVQHLMTVLIRKHSQLF--------TAPVPEGPTSPRGGL 364
               L+  LI  + Q+F        T P P+  +   G L
Sbjct: 741 HQAQLVEFLIVHYEQIFGMDELPQATEPPPQDSSPAPGPL 780


>gi|194272142 myosin IXB isoform 2 [Homo sapiens]
          Length = 2022

 Score =  100 bits (250), Expect = 3e-21
 Identities = 58/184 (31%), Positives = 99/184 (53%), Gaps = 3/184 (1%)

Query: 173  PLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASLLK 232
            P+++E+ ++ +   GL  EGL+R  G AN  R+L+ +       +      +H +  +LK
Sbjct: 1713 PIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDPAAVKLENFPIHAITGVLK 1772

Query: 233  LYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKFLD 292
             +LRELPEP++ FA+Y DFL   +L  K E    +     + +LP+AN+N L  +   L 
Sbjct: 1773 QWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAV--LEHLPEANHNSLERLIFHLV 1830

Query: 293  EVQAYSNVNKMSVQNLATVFGPNILR-PQVEDPVTIMEGTSLVQHLMTVLIRKHSQLFTA 351
            +V    +VN+MS   LA +F P +LR P   DP+T M+    +   + +LI++  + +  
Sbjct: 1831 KVALLEDVNRMSPGALAIIFAPCLLRCPDNSDPLTSMKDVLKITTCVEMLIKEQMRKYKV 1890

Query: 352  PVPE 355
             + E
Sbjct: 1891 KMEE 1894


>gi|33356170 myosin IXB isoform 1 [Homo sapiens]
          Length = 2157

 Score =  100 bits (250), Expect = 3e-21
 Identities = 58/184 (31%), Positives = 99/184 (53%), Gaps = 3/184 (1%)

Query: 173  PLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASLLK 232
            P+++E+ ++ +   GL  EGL+R  G AN  R+L+ +       +      +H +  +LK
Sbjct: 1713 PIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDPAAVKLENFPIHAITGVLK 1772

Query: 233  LYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKFLD 292
             +LRELPEP++ FA+Y DFL   +L  K E    +     + +LP+AN+N L  +   L 
Sbjct: 1773 QWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAV--LEHLPEANHNSLERLIFHLV 1830

Query: 293  EVQAYSNVNKMSVQNLATVFGPNILR-PQVEDPVTIMEGTSLVQHLMTVLIRKHSQLFTA 351
            +V    +VN+MS   LA +F P +LR P   DP+T M+    +   + +LI++  + +  
Sbjct: 1831 KVALLEDVNRMSPGALAIIFAPCLLRCPDNSDPLTSMKDVLKITTCVEMLIKEQMRKYKV 1890

Query: 352  PVPE 355
             + E
Sbjct: 1891 KMEE 1894


>gi|50843948 Rho GTPase activating protein 10 [Homo sapiens]
          Length = 786

 Score =  100 bits (249), Expect = 5e-21
 Identities = 107/428 (25%), Positives = 178/428 (41%), Gaps = 39/428 (9%)

Query: 122 ALLLMASSQRDMEDWVQAIRRVIWAPLGGGIFGQRLEETVHHERKYG----PRLAPLLVE 177
           +L + A S+ + + W++A        LGG         T    R  G     ++   ++ 
Sbjct: 349 SLTMQAFSEEERKQWLEA--------LGGKEALSHSFNTAIIPRPEGNAQLDKMGFTIIR 400

Query: 178 QCVDFIRERGLTEEGLFRMPGQANLVRDL----QDSFDCGEKPLFDSTT-DVHTVASLLK 232
           +C+  +  RG+ ++GL+R+ G ++ V+ L     D   C E  L +S   +V T+ S LK
Sbjct: 401 KCISAVETRGINDQGLYRVVGVSSKVQRLLSMLMDVKTCNEVDLENSADWEVKTITSALK 460

Query: 233 LYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKFLD 292
            YLR LPEP++ +  + DF+  A+  + +     +     V  LP+ N  +L  + K L 
Sbjct: 461 QYLRSLPEPLMTYELHGDFIVPAKSGSPESRVNAIHFL--VHKLPEKNKEMLDILVKHLT 518

Query: 293 EVQAYSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIRKHSQLFTAP 352
            V  +S  N M+V NL  VFGP ++RPQ E    +M+       ++ +LI  H ++F   
Sbjct: 519 NVSNHSKQNLMTVANLGVVFGPTLMRPQEETVAALMD-LKFQNIVVEILIENHEKIFR-- 575

Query: 353 VPEGPTSPRGGLQCAVGWGSEEVTRDSQGEPGGPGLPAHRTSSLDGAAVAVLSRTAPTGP 412
            P   T P             E T  S   P  P   + R        VAV +       
Sbjct: 576 TPPDTTFP-------------EPTCLSASPPNAPPRQSKRQGQRTKRPVAVYNLCLELED 622

Query: 413 GSRCSPGKKVQTLPSWKSSFRQPRSLSGSPKGGGSSLEVPIISSGGNWLMNGLSSLRGHR 472
           G    P K+  T  S   S   P  ++ +  G     +  +++ GG++  +  S++ G  
Sbjct: 623 GDNPYPSKE-DTPTSSLDSLSSPSPVTTAVPGPPGPDKNHLLADGGSF-GDWASTIPGQT 680

Query: 473 RASSGDRLKDSGSVQRLSTYDNVP-APGLVP-GIPSVASMAWSGASSSESSVGGSLSSCT 530
           R+S    L         S     P +PG  P      A++A     S  S    ++  C 
Sbjct: 681 RSSMVQWLNPQSPTTTSSNSAVTPLSPGSSPFPFSPPATVADKPPESIRSRKARAVYPCE 740

Query: 531 ACRASDSS 538
           A  +S+ S
Sbjct: 741 AEHSSELS 748


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.132    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,549,283
Number of Sequences: 37866
Number of extensions: 1662529
Number of successful extensions: 9750
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 354
Number of HSP's successfully gapped in prelim test: 562
Number of HSP's that attempted gapping in prelim test: 7040
Number of HSP's gapped (non-prelim): 2902
length of query: 698
length of database: 18,247,518
effective HSP length: 109
effective length of query: 589
effective length of database: 14,120,124
effective search space: 8316753036
effective search space used: 8316753036
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.