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Search of human proteins with 33667061
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|33667061 regulating synaptic membrane exocytosis 4 [Homo
sapiens]
(269 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|33667061 regulating synaptic membrane exocytosis 4 [Homo sapi... 531 e-151
gi|154354983 regulating synaptic membrane exocytosis 2 isoform a... 326 1e-89
gi|154354981 regulating synaptic membrane exocytosis 2 isoform b... 326 1e-89
gi|41054864 regulating synaptic membrane exocytosis 1 [Homo sapi... 315 3e-86
gi|48476344 regulating synaptic membrane exocytosis 3 [Homo sapi... 293 8e-80
gi|150378539 piccolo isoform 1 [Homo sapiens] 75 5e-14
gi|194097347 phosphoinositide-3-kinase, class 2 beta polypeptide... 67 1e-11
gi|157671929 phosphoinositide-3-kinase, class 2 alpha polypeptid... 59 6e-09
gi|38570146 synaptotagmin VII [Homo sapiens] 57 2e-08
gi|14249614 synaptotagmin-like 1 [Homo sapiens] 53 2e-07
gi|150170670 piccolo isoform 2 [Homo sapiens] 52 4e-07
gi|15011900 synaptotagmin-like 2 isoform b [Homo sapiens] 52 7e-07
gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens] 52 7e-07
gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens] 52 7e-07
gi|244790016 synaptotagmin-like 2 isoform h [Homo sapiens] 52 7e-07
gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens] 52 7e-07
gi|46255068 synaptotagmin-like 2 isoform f [Homo sapiens] 52 7e-07
gi|46255066 synaptotagmin-like 2 isoform e [Homo sapiens] 52 7e-07
gi|46255064 synaptotagmin-like 2 isoform d [Homo sapiens] 52 7e-07
gi|46255062 synaptotagmin-like 2 isoform c [Homo sapiens] 52 7e-07
gi|110227631 synaptotagmin-like 3 [Homo sapiens] 49 6e-06
gi|193804862 synaptotagmin-like 4 [Homo sapiens] 48 8e-06
gi|193804860 synaptotagmin-like 4 [Homo sapiens] 48 8e-06
gi|45504376 synaptotagmin VI [Homo sapiens] 47 2e-05
gi|238550198 synaptotagmin III [Homo sapiens] 46 3e-05
gi|238550196 synaptotagmin III [Homo sapiens] 46 3e-05
gi|14150054 synaptotagmin III [Homo sapiens] 46 3e-05
gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens] 45 5e-05
gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens] 45 5e-05
gi|20270305 synaptotagmin-like 5 isoform 1 [Homo sapiens] 45 5e-05
>gi|33667061 regulating synaptic membrane exocytosis 4 [Homo
sapiens]
Length = 269
Score = 531 bits (1367), Expect = e-151
Identities = 269/269 (100%), Positives = 269/269 (100%)
Query: 1 MERSQSRLSLSASFEALAIYFPCMNSFDDEDAGDSRRLKGAIQRSTETGLAVEMPSRTLR 60
MERSQSRLSLSASFEALAIYFPCMNSFDDEDAGDSRRLKGAIQRSTETGLAVEMPSRTLR
Sbjct: 1 MERSQSRLSLSASFEALAIYFPCMNSFDDEDAGDSRRLKGAIQRSTETGLAVEMPSRTLR 60
Query: 61 QASHESIEDSMNSYGSEGNLNYGGVCLASDAQFSDFLGSMGPAQFVGRQTLATTPMGDVE 120
QASHESIEDSMNSYGSEGNLNYGGVCLASDAQFSDFLGSMGPAQFVGRQTLATTPMGDVE
Sbjct: 61 QASHESIEDSMNSYGSEGNLNYGGVCLASDAQFSDFLGSMGPAQFVGRQTLATTPMGDVE 120
Query: 121 IGLQERNGQLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKKTKVARKSLDPL 180
IGLQERNGQLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKKTKVARKSLDPL
Sbjct: 121 IGLQERNGQLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKKTKVARKSLDPL 180
Query: 181 YNQVLLFPESPQGKVLQVIVWGNYGRMERKQFMGVARVLLEELDLTTLAVGWYKLFPTSS 240
YNQVLLFPESPQGKVLQVIVWGNYGRMERKQFMGVARVLLEELDLTTLAVGWYKLFPTSS
Sbjct: 181 YNQVLLFPESPQGKVLQVIVWGNYGRMERKQFMGVARVLLEELDLTTLAVGWYKLFPTSS 240
Query: 241 MVDPATGPLLRQASQLSLESTVGPCGERS 269
MVDPATGPLLRQASQLSLESTVGPCGERS
Sbjct: 241 MVDPATGPLLRQASQLSLESTVGPCGERS 269
>gi|154354983 regulating synaptic membrane exocytosis 2 isoform a
[Homo sapiens]
Length = 1349
Score = 326 bits (835), Expect = 1e-89
Identities = 159/241 (65%), Positives = 196/241 (81%), Gaps = 1/241 (0%)
Query: 29 DEDAGDSRRLKGAIQRSTETGLAVEMPSRTLRQASHESIEDSMNSYGSEGNLNYGGVCLA 88
D AG ++L+ +QRSTETGLAVEM + RQAS ES + SMNSY SEGNL + GV LA
Sbjct: 1110 DRKAG-GKKLRSTVQRSTETGLAVEMRNWMTRQASRESTDGSMNSYSSEGNLIFPGVRLA 1168
Query: 89 SDAQFSDFLGSMGPAQFVGRQTLATTPMGDVEIGLQERNGQLEVDIIQARGLTAKPGSKT 148
SD+QFSDFL +GPAQ VGRQTLAT MGD+++G+ ++ GQLEV+II+ARGL KPGSKT
Sbjct: 1169 SDSQFSDFLDGLGPAQLVGRQTLATPAMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKT 1228
Query: 149 LPAAYIKAYLLENGICIAKKKTKVARKSLDPLYNQVLLFPESPQGKVLQVIVWGNYGRME 208
LPA Y+K YLL+NG+CIAKKKTKVARK+L+PLY Q+L F ESPQGKVLQ+IVWG+YGRM+
Sbjct: 1229 LPAPYVKVYLLDNGVCIAKKKTKVARKTLEPLYQQLLSFEESPQGKVLQIIVWGDYGRMD 1288
Query: 209 RKQFMGVARVLLEELDLTTLAVGWYKLFPTSSMVDPATGPLLRQASQLSLESTVGPCGER 268
K FMGVA++LL+EL+L+ + +GW+KLFP SS+VDP PL R+ASQ SLES+ GP R
Sbjct: 1289 HKSFMGVAQILLDELELSNMVIGWFKLFPPSSLVDPTLAPLTRRASQSSLESSTGPSYSR 1348
Query: 269 S 269
S
Sbjct: 1349 S 1349
Score = 51.2 bits (121), Expect = 9e-07
Identities = 50/205 (24%), Positives = 94/205 (45%), Gaps = 22/205 (10%)
Query: 62 ASHESIEDSMNSYGSEGNLNYGGVCLASDAQ------FSDFLGSMGPAQFVGRQTLATTP 115
++H +E S +S+ S+ ++ + + S FL +Q + R+T P
Sbjct: 687 STHAQLESSSSSFESQ-KMDRPSISVTSPMSPGMLRDVPQFLSGQLSSQSLSRRTTPFVP 745
Query: 116 MGDVEIGLQERNGQLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKKTKVARK 175
+++ + QL V I+ A+ L ++ + Y+K Y L + K++TK +K
Sbjct: 746 RVQIKLWFDKVGHQLIVTILGAKDLPSREDGRPRNP-YVKIYFLPDRSDKNKRRTKTVKK 804
Query: 176 SLDPLYNQVLLFPESP------QGKVLQVIVWGNYG-RMERKQFMGVARVLLE-ELDLTT 227
+L+P +NQ ++ SP + ++L++ +W R E +F+G +L+E E L
Sbjct: 805 TLEPKWNQTFIY--SPVHRREFRERMLEITLWDQARVREEESEFLG--EILIELETALLD 860
Query: 228 LAVGWYKL--FPTSSMVDPATGPLL 250
WYKL SS+ P P +
Sbjct: 861 DEPHWYKLQTHDVSSLPLPHPSPYM 885
>gi|154354981 regulating synaptic membrane exocytosis 2 isoform b
[Homo sapiens]
Length = 1163
Score = 326 bits (835), Expect = 1e-89
Identities = 159/241 (65%), Positives = 196/241 (81%), Gaps = 1/241 (0%)
Query: 29 DEDAGDSRRLKGAIQRSTETGLAVEMPSRTLRQASHESIEDSMNSYGSEGNLNYGGVCLA 88
D AG ++L+ +QRSTETGLAVEM + RQAS ES + SMNSY SEGNL + GV LA
Sbjct: 924 DRKAG-GKKLRSTVQRSTETGLAVEMRNWMTRQASRESTDGSMNSYSSEGNLIFPGVRLA 982
Query: 89 SDAQFSDFLGSMGPAQFVGRQTLATTPMGDVEIGLQERNGQLEVDIIQARGLTAKPGSKT 148
SD+QFSDFL +GPAQ VGRQTLAT MGD+++G+ ++ GQLEV+II+ARGL KPGSKT
Sbjct: 983 SDSQFSDFLDGLGPAQLVGRQTLATPAMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKT 1042
Query: 149 LPAAYIKAYLLENGICIAKKKTKVARKSLDPLYNQVLLFPESPQGKVLQVIVWGNYGRME 208
LPA Y+K YLL+NG+CIAKKKTKVARK+L+PLY Q+L F ESPQGKVLQ+IVWG+YGRM+
Sbjct: 1043 LPAPYVKVYLLDNGVCIAKKKTKVARKTLEPLYQQLLSFEESPQGKVLQIIVWGDYGRMD 1102
Query: 209 RKQFMGVARVLLEELDLTTLAVGWYKLFPTSSMVDPATGPLLRQASQLSLESTVGPCGER 268
K FMGVA++LL+EL+L+ + +GW+KLFP SS+VDP PL R+ASQ SLES+ GP R
Sbjct: 1103 HKSFMGVAQILLDELELSNMVIGWFKLFPPSSLVDPTLAPLTRRASQSSLESSTGPSYSR 1162
Query: 269 S 269
S
Sbjct: 1163 S 1163
Score = 42.0 bits (97), Expect = 6e-04
Identities = 38/132 (28%), Positives = 65/132 (49%), Gaps = 15/132 (11%)
Query: 129 QLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKKTKVARKSLDPLYNQVLLFP 188
QL V I+ A+ L ++ + Y+K Y L + K++TK +K+L+P +NQ ++
Sbjct: 551 QLIVTILGAKDLPSREDGRPRNP-YVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIY- 608
Query: 189 ESP------QGKVLQVIVWGNYG-RMERKQFMGVARVLLE-ELDLTTLAVGWYKL--FPT 238
SP + ++L++ +W R E +F+G +L+E E L WYKL
Sbjct: 609 -SPVHRREFRERMLEITLWDQARVREEESEFLG--EILIELETALLDDEPHWYKLQTHDV 665
Query: 239 SSMVDPATGPLL 250
SS+ P P +
Sbjct: 666 SSLPLPHPSPYM 677
>gi|41054864 regulating synaptic membrane exocytosis 1 [Homo sapiens]
Length = 1692
Score = 315 bits (807), Expect = 3e-86
Identities = 159/258 (61%), Positives = 198/258 (76%), Gaps = 1/258 (0%)
Query: 7 RLSLSASFEALAIYFPCMNSFDDEDAGDSRRLKGAIQRSTETGLAVEMPSRTLRQASHES 66
R SLSA A+ S + ++LK IQRSTETG+A EM + +RQ S ES
Sbjct: 1431 RSSLSAKVVAIVSRRSRSTSQLSQTESGHKKLKSTIQRSTETGMAAEM-RKMVRQPSRES 1489
Query: 67 IEDSMNSYGSEGNLNYGGVCLASDAQFSDFLGSMGPAQFVGRQTLATTPMGDVEIGLQER 126
+ S+NSY SEGNL + GV L +D+QFSDFL +GPAQ VGRQTLAT MGD++IG++++
Sbjct: 1490 TDGSINSYSSEGNLIFPGVRLGADSQFSDFLDGLGPAQLVGRQTLATPAMGDIQIGMEDK 1549
Query: 127 NGQLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKKTKVARKSLDPLYNQVLL 186
GQLEV++I+AR LT KPGSK+ PA Y+K YLLENG CIAKKKT++ARK+LDPLY Q L+
Sbjct: 1550 KGQLEVEVIRARSLTQKPGSKSTPAPYVKVYLLENGACIAKKKTRIARKTLDPLYQQSLV 1609
Query: 187 FPESPQGKVLQVIVWGNYGRMERKQFMGVARVLLEELDLTTLAVGWYKLFPTSSMVDPAT 246
F ESPQGKVLQVIVWG+YGRM+ K FMGVA++LLEELDL+++ +GWYKLFP SS+VDP
Sbjct: 1610 FDESPQGKVLQVIVWGDYGRMDHKCFMGVAQILLEELDLSSMVIGWYKLFPPSSLVDPTL 1669
Query: 247 GPLLRQASQLSLESTVGP 264
PL R+ASQ SLES+ GP
Sbjct: 1670 TPLTRRASQSSLESSTGP 1687
Score = 44.3 bits (103), Expect = 1e-04
Identities = 35/129 (27%), Positives = 65/129 (50%), Gaps = 9/129 (6%)
Query: 129 QLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKKTKVARKSLDPLYNQVLLFP 188
QL V+++QA L A+ + Y+K Y L + +K++TK +K L+P +NQ ++
Sbjct: 758 QLIVNVLQATDLPARVDGRPRNP-YVKMYFLPDRSDKSKRRTKTVKKILEPKWNQTFVYS 816
Query: 189 ----ESPQGKVLQVIVWGNYGRMERKQFMGVARVLLE-ELDLTTLAVGWYKL--FPTSSM 241
+ ++L++ VW + R++ ++ + +L+E E L WYKL SS+
Sbjct: 817 HVHRRDFRERMLEITVW-DQPRVQEEESEFLGEILIELETALLDDEPHWYKLQTHDESSL 875
Query: 242 VDPATGPLL 250
P P +
Sbjct: 876 PLPQPSPFM 884
>gi|48476344 regulating synaptic membrane exocytosis 3 [Homo
sapiens]
Length = 308
Score = 293 bits (751), Expect = 8e-80
Identities = 143/232 (61%), Positives = 177/232 (76%)
Query: 33 GDSRRLKGAIQRSTETGLAVEMPSRTLRQASHESIEDSMNSYGSEGNLNYGGVCLASDAQ 92
G +++L+ I+RSTETG+AVEM SR RQ S ES + S NS S+G + L +++Q
Sbjct: 74 GATKKLRSNIRRSTETGIAVEMRSRVTRQGSRESTDGSTNSNSSDGTFIFPTTRLGAESQ 133
Query: 93 FSDFLGSMGPAQFVGRQTLATTPMGDVEIGLQERNGQLEVDIIQARGLTAKPGSKTLPAA 152
FSDFL +GPAQ VGRQTLAT PMGDV I + +R+GQLEV++I+ARGLT KPGSK+LPA
Sbjct: 134 FSDFLDGLGPAQIVGRQTLATPPMGDVHIAIMDRSGQLEVEVIEARGLTPKPGSKSLPAT 193
Query: 153 YIKAYLLENGICIAKKKTKVARKSLDPLYNQVLLFPESPQGKVLQVIVWGNYGRMERKQF 212
YIK YLLENG C+AKKKTK+ +K+ DPLY Q LLF E PQGKVLQVIVWG+YGRM+ K F
Sbjct: 194 YIKVYLLENGACLAKKKTKMTKKTCDPLYQQALLFDEGPQGKVLQVIVWGDYGRMDHKCF 253
Query: 213 MGVARVLLEELDLTTLAVGWYKLFPTSSMVDPATGPLLRQASQLSLESTVGP 264
MG+A+++L+ELDL+ GWYKLFPTSS+ D G L R+ SQ SLES P
Sbjct: 254 MGMAQIMLDELDLSAAVTGWYKLFPTSSVADSTLGSLTRRLSQSSLESATSP 305
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 75.5 bits (184), Expect = 5e-14
Identities = 45/130 (34%), Positives = 73/130 (56%), Gaps = 7/130 (5%)
Query: 113 TTPMGDVEIGLQER----NGQLEVDIIQARGLTAKPGSKT-LPAAYIKAYLLENGIC--I 165
T MG+++I L++ QL V+I+Q R +T K S LP Y+K Y++ +
Sbjct: 5005 TQVMGEIKIALKKEMKTDGEQLIVEILQCRNITYKFKSPDHLPDLYVKIYVMNISTQKKV 5064
Query: 166 AKKKTKVARKSLDPLYNQVLLFPESPQGKVLQVIVWGNYGRMERKQFMGVARVLLEELDL 225
KKKT+V R +P +N+ F SP G LQ++++ N G+ +K +G A + L+++DL
Sbjct: 5065 IKKKTRVCRHDREPSFNETFRFSLSPAGHSLQILLFSNGGKFMKKTLIGEACIWLDKVDL 5124
Query: 226 TTLAVGWYKL 235
V W+KL
Sbjct: 5125 RKRIVNWHKL 5134
Score = 52.4 bits (124), Expect = 4e-07
Identities = 41/159 (25%), Positives = 71/159 (44%), Gaps = 17/159 (10%)
Query: 98 GSMGPAQFVGRQTLATTPMGDVEIGLQERNGQLEVDIIQARGLTAKPGSKTLPAAYIKAY 157
GS P G + ++ G++++ + G L + I+QAR L + + ++K Y
Sbjct: 4679 GSSKPTD--GTKVVSHPITGEIQLQINYDLGNLIIHILQARNLVPRDNNG-YSDPFVKVY 4735
Query: 158 LL---------ENGICIAKKKTKVARKSLDPLYNQVLLFP----ESPQGKVLQVIVWGNY 204
LL +N K++TK +KSL+P +NQ +++ E + K L+V VW +Y
Sbjct: 4736 LLPGRGQVMVVQNASAEYKRRTKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVW-DY 4794
Query: 205 GRMERKQFMGVARVLLEELDLTTLAVGWYKLFPTSSMVD 243
R F+G + L WY L + +D
Sbjct: 4795 DRFSSNDFLGEVLIDLSSTSHLDNTPRWYPLKEQTESID 4833
>gi|194097347 phosphoinositide-3-kinase, class 2 beta polypeptide
[Homo sapiens]
Length = 1634
Score = 67.4 bits (163), Expect = 1e-11
Identities = 41/123 (33%), Positives = 65/123 (52%), Gaps = 6/123 (4%)
Query: 117 GDVEIGLQERNGQLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKKTKVARKS 176
G+V++ + +N +L + ++ RGL P Y+K YLL + K+KTKVARK+
Sbjct: 1506 GEVKLSISYKNNKLFIMVMHIRGLQLLQDGND-PDPYVKIYLLPDPQKTTKRKTKVARKT 1564
Query: 177 LDPLYNQVLLFPESPQG----KVLQVIVWGNYGRMERKQFMGVARVLLEELDLTTLAVGW 232
+P YN++L++ P+G + LQ+ V G E +G + L ELDL GW
Sbjct: 1565 CNPTYNEMLVYDGIPKGDLQQRELQLSVLSEQGFWE-NVLLGEVNIRLRELDLAQEKTGW 1623
Query: 233 YKL 235
+ L
Sbjct: 1624 FAL 1626
>gi|157671929 phosphoinositide-3-kinase, class 2 alpha polypeptide
[Homo sapiens]
Length = 1686
Score = 58.5 bits (140), Expect = 6e-09
Identities = 35/123 (28%), Positives = 70/123 (56%), Gaps = 7/123 (5%)
Query: 117 GDVEIGLQERNGQLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKKTKVARKS 176
G V++ + RNG L + ++ + L + G+ P Y+K YLL + +K+KTK++RK+
Sbjct: 1561 GAVKLSISYRNGTLFIMVMHIKDLVTEDGAD--PNPYVKTYLLPDNHKTSKRKTKISRKT 1618
Query: 177 LDPLYNQVLLF----PESPQGKVLQVIVWGNYGRMERKQFMGVARVLLEELDLTTLAVGW 232
+P +N++L++ E+ + + LQ+ V + + F+G + L++ +L+ V W
Sbjct: 1619 RNPTFNEMLVYSGYSKETLRQRELQLSVL-SAESLRENFFLGGVTLPLKDFNLSKETVKW 1677
Query: 233 YKL 235
Y+L
Sbjct: 1678 YQL 1680
>gi|38570146 synaptotagmin VII [Homo sapiens]
Length = 403
Score = 56.6 bits (135), Expect = 2e-08
Identities = 42/122 (34%), Positives = 64/122 (52%), Gaps = 6/122 (4%)
Query: 121 IGLQERNGQLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKKTKVARKSLDPL 180
+G + L V I++A+ L AK S T ++K YLL + K +TKV RK+L+P
Sbjct: 143 VGYNFQESTLTVKIMKAQELPAKDFSGTSDP-FVKIYLLPDKK--HKLETKVKRKNLNPH 199
Query: 181 YNQVLLFPESPQGKVLQVIVW---GNYGRMERKQFMGVARVLLEELDLTTLAVGWYKLFP 237
+N+ LF P KV+Q I++ +Y R R +G + L ++DLT + W L P
Sbjct: 200 WNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTFWKDLKP 259
Query: 238 TS 239
S
Sbjct: 260 CS 261
Score = 34.7 bits (78), Expect = 0.090
Identities = 20/57 (35%), Positives = 34/57 (59%), Gaps = 3/57 (5%)
Query: 132 VDIIQARGLTAKP-GSKTLPAAYIKAYLLENGICIAKKKTKVARKSLDPLYNQVLLF 187
V+II+AR L A G + P Y+K +L+ + KKKT +++L+P++N+ F
Sbjct: 285 VNIIKARNLKAMDIGGTSDP--YVKVWLMYKDKRVEKKKTVTMKRNLNPIFNESFAF 339
>gi|14249614 synaptotagmin-like 1 [Homo sapiens]
Length = 550
Score = 53.1 bits (126), Expect = 2e-07
Identities = 49/177 (27%), Positives = 88/177 (49%), Gaps = 15/177 (8%)
Query: 55 PSRTLRQASHESIEDSMNSYGSEGNLNYGGVCLASDAQFSDFLGSM--GPAQFVGRQTLA 112
P + +A+ + +E+ + G + +L+ L+S + S S G + A
Sbjct: 195 PQQAQTKAASQILENGEEAPGPDPSLDR---MLSSSSSVSSLNSSTLSGSQMSLSGDAEA 251
Query: 113 TTPMGDVEIGLQERNG--QLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKKT 170
G V L G +L V +IQ +GL A ++ P Y+K+YLL + +K+KT
Sbjct: 252 VQVRGSVHFALHYEPGAAELRVHVIQCQGLAAARRRRSDP--YVKSYLLPDKQ--SKRKT 307
Query: 171 KVARKSLDPLYNQVLLF--PESP-QGKVLQVIVWGNYGRMERKQFMGVARVLLEELD 224
V +++L+P++N+ L + P++ QG+VL + VW + + R F+G V L+ D
Sbjct: 308 AVKKRNLNPVFNETLRYSVPQAELQGRVLSLSVW-HRESLGRNIFLGEVEVPLDTWD 363
Score = 35.4 bits (80), Expect = 0.053
Identities = 32/133 (24%), Positives = 64/133 (48%), Gaps = 11/133 (8%)
Query: 110 TLATTPMGDVEIGLQERNGQLEVDIIQARGLTA-KPGSKTLPAAYIKAYLLENGICIAKK 168
+L P G GL +G+L + +AR L + GS Y++ ++L + +++
Sbjct: 393 SLKYVPAGSEGAGLPP-SGELHFWVKEARDLLPLRAGSLD---TYVQCFVLPDDSQASRQ 448
Query: 169 KTKVARKSLDPLYNQVLLF----PESPQGKVLQVIVWGNYGRMERKQFMGVARVLLEELD 224
+T+V R+SL P++N +++ P + ++ +W ++G + +Q +G R+ L
Sbjct: 449 RTRVVRRSLSPVFNHTMVYDGFGPADLRQACAELSLW-DHGALANRQ-LGGTRLSLGTGS 506
Query: 225 LTTLAVGWYKLFP 237
L V W P
Sbjct: 507 SYGLQVPWMDSTP 519
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 52.4 bits (124), Expect = 4e-07
Identities = 41/159 (25%), Positives = 71/159 (44%), Gaps = 17/159 (10%)
Query: 98 GSMGPAQFVGRQTLATTPMGDVEIGLQERNGQLEVDIIQARGLTAKPGSKTLPAAYIKAY 157
GS P G + ++ G++++ + G L + I+QAR L + + ++K Y
Sbjct: 4679 GSSKPTD--GTKVVSHPITGEIQLQINYDLGNLIIHILQARNLVPRDNNG-YSDPFVKVY 4735
Query: 158 LL---------ENGICIAKKKTKVARKSLDPLYNQVLLFP----ESPQGKVLQVIVWGNY 204
LL +N K++TK +KSL+P +NQ +++ E + K L+V VW +Y
Sbjct: 4736 LLPGRGQVMVVQNASAEYKRRTKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVW-DY 4794
Query: 205 GRMERKQFMGVARVLLEELDLTTLAVGWYKLFPTSSMVD 243
R F+G + L WY L + +D
Sbjct: 4795 DRFSSNDFLGEVLIDLSSTSHLDNTPRWYPLKEQTESID 4833
>gi|15011900 synaptotagmin-like 2 isoform b [Homo sapiens]
Length = 376
Score = 51.6 bits (122), Expect = 7e-07
Identities = 34/113 (30%), Positives = 59/113 (52%), Gaps = 6/113 (5%)
Query: 117 GDVEIGLQ--ERNGQLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKKTKVAR 174
G+++ ++ E +L V + Q + L A K Y+KAYLL + + KKKT V +
Sbjct: 72 GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 131
Query: 175 KSLDPLYNQVLLFPESPQ---GKVLQVIVWGNYGRMERKQFMGVARVLLEELD 224
K+L+P+YN++L + Q + L + +W + +R F+G + LE D
Sbjct: 132 KTLNPVYNEILRYKIEKQILKTQKLNLSIW-HRDTFKRNSFLGEVELDLETWD 183
Score = 31.6 bits (70), Expect = 0.76
Identities = 16/71 (22%), Positives = 38/71 (53%), Gaps = 6/71 (8%)
Query: 152 AYIKAYLLENGICIAKKKTKVARKSLDPLYNQVLLF----PESPQGKVLQVIVWGNYGRM 207
+++K +L + +++KT+ K+ +P++N +++ PE +++ VW +Y
Sbjct: 256 SFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHY--K 313
Query: 208 ERKQFMGVARV 218
QF+G R+
Sbjct: 314 LTNQFLGGLRI 324
>gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens]
Length = 910
Score = 51.6 bits (122), Expect = 7e-07
Identities = 34/113 (30%), Positives = 59/113 (52%), Gaps = 6/113 (5%)
Query: 117 GDVEIGLQ--ERNGQLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKKTKVAR 174
G+++ ++ E +L V + Q + L A K Y+KAYLL + + KKKT V +
Sbjct: 606 GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 665
Query: 175 KSLDPLYNQVLLFPESPQ---GKVLQVIVWGNYGRMERKQFMGVARVLLEELD 224
K+L+P+YN++L + Q + L + +W + +R F+G + LE D
Sbjct: 666 KTLNPVYNEILRYKIEKQILKTQKLNLSIW-HRDTFKRNSFLGEVELDLETWD 717
Score = 31.6 bits (70), Expect = 0.76
Identities = 16/71 (22%), Positives = 38/71 (53%), Gaps = 6/71 (8%)
Query: 152 AYIKAYLLENGICIAKKKTKVARKSLDPLYNQVLLF----PESPQGKVLQVIVWGNYGRM 207
+++K +L + +++KT+ K+ +P++N +++ PE +++ VW +Y
Sbjct: 790 SFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHY--K 847
Query: 208 ERKQFMGVARV 218
QF+G R+
Sbjct: 848 LTNQFLGGLRI 858
>gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens]
Length = 935
Score = 51.6 bits (122), Expect = 7e-07
Identities = 34/113 (30%), Positives = 59/113 (52%), Gaps = 6/113 (5%)
Query: 117 GDVEIGLQ--ERNGQLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKKTKVAR 174
G+++ ++ E +L V + Q + L A K Y+KAYLL + + KKKT V +
Sbjct: 631 GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 690
Query: 175 KSLDPLYNQVLLFPESPQ---GKVLQVIVWGNYGRMERKQFMGVARVLLEELD 224
K+L+P+YN++L + Q + L + +W + +R F+G + LE D
Sbjct: 691 KTLNPVYNEILRYKIEKQILKTQKLNLSIW-HRDTFKRNSFLGEVELDLETWD 742
Score = 31.6 bits (70), Expect = 0.76
Identities = 16/71 (22%), Positives = 38/71 (53%), Gaps = 6/71 (8%)
Query: 152 AYIKAYLLENGICIAKKKTKVARKSLDPLYNQVLLF----PESPQGKVLQVIVWGNYGRM 207
+++K +L + +++KT+ K+ +P++N +++ PE +++ VW +Y
Sbjct: 815 SFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHY--K 872
Query: 208 ERKQFMGVARV 218
QF+G R+
Sbjct: 873 LTNQFLGGLRI 883
>gi|244790016 synaptotagmin-like 2 isoform h [Homo sapiens]
Length = 336
Score = 51.6 bits (122), Expect = 7e-07
Identities = 34/113 (30%), Positives = 59/113 (52%), Gaps = 6/113 (5%)
Query: 117 GDVEIGLQ--ERNGQLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKKTKVAR 174
G+++ ++ E +L V + Q + L A K Y+KAYLL + + KKKT V +
Sbjct: 32 GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 91
Query: 175 KSLDPLYNQVLLFPESPQ---GKVLQVIVWGNYGRMERKQFMGVARVLLEELD 224
K+L+P+YN++L + Q + L + +W + +R F+G + LE D
Sbjct: 92 KTLNPVYNEILRYKIEKQILKTQKLNLSIW-HRDTFKRNSFLGEVELDLETWD 143
Score = 31.6 bits (70), Expect = 0.76
Identities = 16/71 (22%), Positives = 38/71 (53%), Gaps = 6/71 (8%)
Query: 152 AYIKAYLLENGICIAKKKTKVARKSLDPLYNQVLLF----PESPQGKVLQVIVWGNYGRM 207
+++K +L + +++KT+ K+ +P++N +++ PE +++ VW +Y
Sbjct: 216 SFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHY--K 273
Query: 208 ERKQFMGVARV 218
QF+G R+
Sbjct: 274 LTNQFLGGLRI 284
>gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens]
Length = 934
Score = 51.6 bits (122), Expect = 7e-07
Identities = 34/113 (30%), Positives = 59/113 (52%), Gaps = 6/113 (5%)
Query: 117 GDVEIGLQ--ERNGQLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKKTKVAR 174
G+++ ++ E +L V + Q + L A K Y+KAYLL + + KKKT V +
Sbjct: 630 GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 689
Query: 175 KSLDPLYNQVLLFPESPQ---GKVLQVIVWGNYGRMERKQFMGVARVLLEELD 224
K+L+P+YN++L + Q + L + +W + +R F+G + LE D
Sbjct: 690 KTLNPVYNEILRYKIEKQILKTQKLNLSIW-HRDTFKRNSFLGEVELDLETWD 741
Score = 31.6 bits (70), Expect = 0.76
Identities = 16/71 (22%), Positives = 38/71 (53%), Gaps = 6/71 (8%)
Query: 152 AYIKAYLLENGICIAKKKTKVARKSLDPLYNQVLLF----PESPQGKVLQVIVWGNYGRM 207
+++K +L + +++KT+ K+ +P++N +++ PE +++ VW +Y
Sbjct: 814 SFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHY--K 871
Query: 208 ERKQFMGVARV 218
QF+G R+
Sbjct: 872 LTNQFLGGLRI 882
>gi|46255068 synaptotagmin-like 2 isoform f [Homo sapiens]
Length = 365
Score = 51.6 bits (122), Expect = 7e-07
Identities = 34/113 (30%), Positives = 59/113 (52%), Gaps = 6/113 (5%)
Query: 117 GDVEIGLQ--ERNGQLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKKTKVAR 174
G+++ ++ E +L V + Q + L A K Y+KAYLL + + KKKT V +
Sbjct: 61 GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 120
Query: 175 KSLDPLYNQVLLFPESPQ---GKVLQVIVWGNYGRMERKQFMGVARVLLEELD 224
K+L+P+YN++L + Q + L + +W + +R F+G + LE D
Sbjct: 121 KTLNPVYNEILRYKIEKQILKTQKLNLSIW-HRDTFKRNSFLGEVELDLETWD 172
Score = 31.6 bits (70), Expect = 0.76
Identities = 16/71 (22%), Positives = 38/71 (53%), Gaps = 6/71 (8%)
Query: 152 AYIKAYLLENGICIAKKKTKVARKSLDPLYNQVLLF----PESPQGKVLQVIVWGNYGRM 207
+++K +L + +++KT+ K+ +P++N +++ PE +++ VW +Y
Sbjct: 245 SFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHY--K 302
Query: 208 ERKQFMGVARV 218
QF+G R+
Sbjct: 303 LTNQFLGGLRI 313
>gi|46255066 synaptotagmin-like 2 isoform e [Homo sapiens]
Length = 376
Score = 51.6 bits (122), Expect = 7e-07
Identities = 34/113 (30%), Positives = 59/113 (52%), Gaps = 6/113 (5%)
Query: 117 GDVEIGLQ--ERNGQLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKKTKVAR 174
G+++ ++ E +L V + Q + L A K Y+KAYLL + + KKKT V +
Sbjct: 72 GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 131
Query: 175 KSLDPLYNQVLLFPESPQ---GKVLQVIVWGNYGRMERKQFMGVARVLLEELD 224
K+L+P+YN++L + Q + L + +W + +R F+G + LE D
Sbjct: 132 KTLNPVYNEILRYKIEKQILKTQKLNLSIW-HRDTFKRNSFLGEVELDLETWD 183
Score = 31.6 bits (70), Expect = 0.76
Identities = 16/71 (22%), Positives = 38/71 (53%), Gaps = 6/71 (8%)
Query: 152 AYIKAYLLENGICIAKKKTKVARKSLDPLYNQVLLF----PESPQGKVLQVIVWGNYGRM 207
+++K +L + +++KT+ K+ +P++N +++ PE +++ VW +Y
Sbjct: 256 SFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHY--K 313
Query: 208 ERKQFMGVARV 218
QF+G R+
Sbjct: 314 LTNQFLGGLRI 324
>gi|46255064 synaptotagmin-like 2 isoform d [Homo sapiens]
Length = 1256
Score = 51.6 bits (122), Expect = 7e-07
Identities = 34/113 (30%), Positives = 59/113 (52%), Gaps = 6/113 (5%)
Query: 117 GDVEIGLQ--ERNGQLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKKTKVAR 174
G+++ ++ E +L V + Q + L A K Y+KAYLL + + KKKT V +
Sbjct: 952 GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 1011
Query: 175 KSLDPLYNQVLLFPESPQ---GKVLQVIVWGNYGRMERKQFMGVARVLLEELD 224
K+L+P+YN++L + Q + L + +W + +R F+G + LE D
Sbjct: 1012 KTLNPVYNEILRYKIEKQILKTQKLNLSIW-HRDTFKRNSFLGEVELDLETWD 1063
Score = 31.6 bits (70), Expect = 0.76
Identities = 16/71 (22%), Positives = 38/71 (53%), Gaps = 6/71 (8%)
Query: 152 AYIKAYLLENGICIAKKKTKVARKSLDPLYNQVLLF----PESPQGKVLQVIVWGNYGRM 207
+++K +L + +++KT+ K+ +P++N +++ PE +++ VW +Y
Sbjct: 1136 SFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHY--K 1193
Query: 208 ERKQFMGVARV 218
QF+G R+
Sbjct: 1194 LTNQFLGGLRI 1204
>gi|46255062 synaptotagmin-like 2 isoform c [Homo sapiens]
Length = 1272
Score = 51.6 bits (122), Expect = 7e-07
Identities = 34/113 (30%), Positives = 59/113 (52%), Gaps = 6/113 (5%)
Query: 117 GDVEIGLQ--ERNGQLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKKTKVAR 174
G+++ ++ E +L V + Q + L A K Y+KAYLL + + KKKT V +
Sbjct: 968 GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 1027
Query: 175 KSLDPLYNQVLLFPESPQ---GKVLQVIVWGNYGRMERKQFMGVARVLLEELD 224
K+L+P+YN++L + Q + L + +W + +R F+G + LE D
Sbjct: 1028 KTLNPVYNEILRYKIEKQILKTQKLNLSIW-HRDTFKRNSFLGEVELDLETWD 1079
Score = 31.6 bits (70), Expect = 0.76
Identities = 16/71 (22%), Positives = 38/71 (53%), Gaps = 6/71 (8%)
Query: 152 AYIKAYLLENGICIAKKKTKVARKSLDPLYNQVLLF----PESPQGKVLQVIVWGNYGRM 207
+++K +L + +++KT+ K+ +P++N +++ PE +++ VW +Y
Sbjct: 1152 SFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHY--K 1209
Query: 208 ERKQFMGVARV 218
QF+G R+
Sbjct: 1210 LTNQFLGGLRI 1220
>gi|110227631 synaptotagmin-like 3 [Homo sapiens]
Length = 542
Score = 48.5 bits (114), Expect = 6e-06
Identities = 37/127 (29%), Positives = 59/127 (46%), Gaps = 9/127 (7%)
Query: 117 GDVEIGLQE--RNGQLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKKTKVAR 174
G++E + + LE+ I + L K Y+K YLL + K+KT V R
Sbjct: 240 GEIEFAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPYVKTYLLPDRSSQGKRKTGVQR 299
Query: 175 KSLDPLYNQVLLFPESPQGKV---LQVIVWGNYGRMERKQFMGVARVLLEELDL---TTL 228
++DP + + L + +P V LQV VW + G + R+ F+G + L D TT
Sbjct: 300 NTVDPTFQETLKYQVAPAQLVTRQLQVSVW-HLGTLARRVFLGEVIIPLATWDFEDSTTQ 358
Query: 229 AVGWYKL 235
+ W+ L
Sbjct: 359 SFRWHPL 365
>gi|193804862 synaptotagmin-like 4 [Homo sapiens]
Length = 671
Score = 48.1 bits (113), Expect = 8e-06
Identities = 31/105 (29%), Positives = 54/105 (51%), Gaps = 4/105 (3%)
Query: 124 QERNGQLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKKTKVARKSLDPLYNQ 183
+++ L V + + L +K Y+K YLL + K+KT + R +++PLY++
Sbjct: 367 EQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDE 426
Query: 184 VLLF--PESPQG-KVLQVIVWGNYGRMERKQFMGVARVLLEELDL 225
L + PES + LQ VW ++GR R F+G A + ++ L
Sbjct: 427 TLRYEIPESLLAQRTLQFSVW-HHGRFGRNTFLGEAEIQMDSWKL 470
Score = 43.1 bits (100), Expect = 3e-04
Identities = 31/93 (33%), Positives = 49/93 (52%), Gaps = 6/93 (6%)
Query: 114 TPMG-DVEIGLQERNGQLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKKTKV 172
TP+G D + G+L+V I +A+ LTA T + ++K YLL +K+KT V
Sbjct: 511 TPVGGDRKKSKGGEGGELQVWIKEAKNLTAAKAGGTSDS-FVKGYLLPMRNKASKRKTPV 569
Query: 173 ARKSLDPLYNQVLLFP----ESPQGKVLQVIVW 201
+K+L+P YN ++ E Q L++ VW
Sbjct: 570 MKKTLNPHYNHTFVYNGVRLEDLQHMCLELTVW 602
>gi|193804860 synaptotagmin-like 4 [Homo sapiens]
Length = 671
Score = 48.1 bits (113), Expect = 8e-06
Identities = 31/105 (29%), Positives = 54/105 (51%), Gaps = 4/105 (3%)
Query: 124 QERNGQLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKKTKVARKSLDPLYNQ 183
+++ L V + + L +K Y+K YLL + K+KT + R +++PLY++
Sbjct: 367 EQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDE 426
Query: 184 VLLF--PESPQG-KVLQVIVWGNYGRMERKQFMGVARVLLEELDL 225
L + PES + LQ VW ++GR R F+G A + ++ L
Sbjct: 427 TLRYEIPESLLAQRTLQFSVW-HHGRFGRNTFLGEAEIQMDSWKL 470
Score = 43.1 bits (100), Expect = 3e-04
Identities = 31/93 (33%), Positives = 49/93 (52%), Gaps = 6/93 (6%)
Query: 114 TPMG-DVEIGLQERNGQLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKKTKV 172
TP+G D + G+L+V I +A+ LTA T + ++K YLL +K+KT V
Sbjct: 511 TPVGGDRKKSKGGEGGELQVWIKEAKNLTAAKAGGTSDS-FVKGYLLPMRNKASKRKTPV 569
Query: 173 ARKSLDPLYNQVLLFP----ESPQGKVLQVIVW 201
+K+L+P YN ++ E Q L++ VW
Sbjct: 570 MKKTLNPHYNHTFVYNGVRLEDLQHMCLELTVW 602
>gi|45504376 synaptotagmin VI [Homo sapiens]
Length = 425
Score = 46.6 bits (109), Expect = 2e-05
Identities = 29/93 (31%), Positives = 52/93 (55%), Gaps = 3/93 (3%)
Query: 128 GQLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKKTKVARKSLDPLYNQVLLF 187
G+L + +I+ R L A + Y+K LL +G + KKKT + + +L+P+YN+ ++F
Sbjct: 291 GRLTLTVIKCRNLKAMDITG-YSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIF 349
Query: 188 PESPQG--KVLQVIVWGNYGRMERKQFMGVARV 218
P+ +V +I +Y R+ + +GV RV
Sbjct: 350 DIPPENMDQVSLLISVMDYDRVGHNEIIGVCRV 382
Score = 35.8 bits (81), Expect = 0.040
Identities = 43/142 (30%), Positives = 66/142 (46%), Gaps = 16/142 (11%)
Query: 112 ATTPMGDVEIGLQE--RNGQLEVDIIQARGLTAKP--GSKTLPAAYIKAYLLENGICIAK 167
AT G + L+ L V I++A L AK GS Y+K YLL + C K
Sbjct: 141 ATKSCGKINFSLRYDYETETLIVRILKAFDLPAKDFCGSSD---PYVKIYLLPDRKC--K 195
Query: 168 KKTKVARKSLDPLYNQVLLFP---ESPQGKVLQVIVWGNYGRMERKQFMG--VARVLLEE 222
+T+V RK+L+P +++ FP E + L + V+ ++ R R +G + L E
Sbjct: 196 LQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVF-DFDRFSRHDMIGEVILDNLFEA 254
Query: 223 LDLTTLAVGWYKL-FPTSSMVD 243
DL+ W + + TS VD
Sbjct: 255 SDLSRETSIWKDIQYATSESVD 276
>gi|238550198 synaptotagmin III [Homo sapiens]
Length = 590
Score = 46.2 bits (108), Expect = 3e-05
Identities = 32/94 (34%), Positives = 51/94 (54%), Gaps = 5/94 (5%)
Query: 128 GQLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKKTKVARKSLDPLYNQVLLF 187
G+L V II+A L A + Y+KA L+ G + K+KT + + +L+P YN+ L+F
Sbjct: 446 GRLTVTIIKASNLKAMDLTG-FSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVF 504
Query: 188 ---PESPQGKVLQVIVWGNYGRMERKQFMGVARV 218
PES + L + V +Y + + +GV RV
Sbjct: 505 DVAPESVENVGLSIAV-VDYDCIGHNEVIGVCRV 537
Score = 38.9 bits (89), Expect = 0.005
Identities = 31/77 (40%), Positives = 41/77 (53%), Gaps = 9/77 (11%)
Query: 115 PMGDVEIGLQERNG--QLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKK--T 170
P G + L+ G QL V I+QA L AK S Y+K YLL + KKK T
Sbjct: 299 PCGRISFALRYLYGSDQLVVRILQALDLPAKD-SNGFSDPYVKIYLLPD----RKKKFQT 353
Query: 171 KVARKSLDPLYNQVLLF 187
KV RK+L+P++N+ F
Sbjct: 354 KVHRKTLNPVFNETFQF 370
>gi|238550196 synaptotagmin III [Homo sapiens]
Length = 590
Score = 46.2 bits (108), Expect = 3e-05
Identities = 32/94 (34%), Positives = 51/94 (54%), Gaps = 5/94 (5%)
Query: 128 GQLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKKTKVARKSLDPLYNQVLLF 187
G+L V II+A L A + Y+KA L+ G + K+KT + + +L+P YN+ L+F
Sbjct: 446 GRLTVTIIKASNLKAMDLTG-FSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVF 504
Query: 188 ---PESPQGKVLQVIVWGNYGRMERKQFMGVARV 218
PES + L + V +Y + + +GV RV
Sbjct: 505 DVAPESVENVGLSIAV-VDYDCIGHNEVIGVCRV 537
Score = 38.9 bits (89), Expect = 0.005
Identities = 31/77 (40%), Positives = 41/77 (53%), Gaps = 9/77 (11%)
Query: 115 PMGDVEIGLQERNG--QLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKK--T 170
P G + L+ G QL V I+QA L AK S Y+K YLL + KKK T
Sbjct: 299 PCGRISFALRYLYGSDQLVVRILQALDLPAKD-SNGFSDPYVKIYLLPD----RKKKFQT 353
Query: 171 KVARKSLDPLYNQVLLF 187
KV RK+L+P++N+ F
Sbjct: 354 KVHRKTLNPVFNETFQF 370
>gi|14150054 synaptotagmin III [Homo sapiens]
Length = 590
Score = 46.2 bits (108), Expect = 3e-05
Identities = 32/94 (34%), Positives = 51/94 (54%), Gaps = 5/94 (5%)
Query: 128 GQLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKKTKVARKSLDPLYNQVLLF 187
G+L V II+A L A + Y+KA L+ G + K+KT + + +L+P YN+ L+F
Sbjct: 446 GRLTVTIIKASNLKAMDLTG-FSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVF 504
Query: 188 ---PESPQGKVLQVIVWGNYGRMERKQFMGVARV 218
PES + L + V +Y + + +GV RV
Sbjct: 505 DVAPESVENVGLSIAV-VDYDCIGHNEVIGVCRV 537
Score = 38.9 bits (89), Expect = 0.005
Identities = 31/77 (40%), Positives = 41/77 (53%), Gaps = 9/77 (11%)
Query: 115 PMGDVEIGLQERNG--QLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKK--T 170
P G + L+ G QL V I+QA L AK S Y+K YLL + KKK T
Sbjct: 299 PCGRISFALRYLYGSDQLVVRILQALDLPAKD-SNGFSDPYVKIYLLPD----RKKKFQT 353
Query: 171 KVARKSLDPLYNQVLLF 187
KV RK+L+P++N+ F
Sbjct: 354 KVHRKTLNPVFNETFQF 370
>gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens]
Length = 730
Score = 45.4 bits (106), Expect = 5e-05
Identities = 32/115 (27%), Positives = 53/115 (46%), Gaps = 5/115 (4%)
Query: 126 RNGQLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKKTKVARKSLDPLYNQVL 185
+ G L + + R L K AY+K+YLL + K+KTK+ R +P +N+ L
Sbjct: 419 KTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKI-RTGTNPEFNETL 477
Query: 186 LFPESP---QGKVLQVIVWGNYGRMERKQFMGVARVLLEELDLTTLAVGWYKLFP 237
+ S + + LQ+ VW +Y R R F+G + + + W+ L P
Sbjct: 478 KYTISHTQLETRTLQLSVW-HYDRFGRNSFLGEVEIPFDSWNFENPTDEWFVLQP 531
Score = 42.4 bits (98), Expect = 4e-04
Identities = 26/78 (33%), Positives = 42/78 (53%), Gaps = 5/78 (6%)
Query: 128 GQLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKKTKVARKSLDPLYNQVLLF 187
G LEV I +A+ LTA T + ++K YLL + K KT V +KS++P +N +F
Sbjct: 587 GILEVFIKEAKNLTAVKSGGTSDS-FVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMF 645
Query: 188 ----PESPQGKVLQVIVW 201
P+ + L++ +W
Sbjct: 646 SGIHPQDIKNVCLELTIW 663
>gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens]
Length = 752
Score = 45.4 bits (106), Expect = 5e-05
Identities = 32/115 (27%), Positives = 53/115 (46%), Gaps = 5/115 (4%)
Query: 126 RNGQLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKKTKVARKSLDPLYNQVL 185
+ G L + + R L K AY+K+YLL + K+KTK+ R +P +N+ L
Sbjct: 441 KTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKI-RTGTNPEFNETL 499
Query: 186 LFPESP---QGKVLQVIVWGNYGRMERKQFMGVARVLLEELDLTTLAVGWYKLFP 237
+ S + + LQ+ VW +Y R R F+G + + + W+ L P
Sbjct: 500 KYTISHTQLETRTLQLSVW-HYDRFGRNSFLGEVEIPFDSWNFENPTDEWFVLQP 553
Score = 42.4 bits (98), Expect = 4e-04
Identities = 26/78 (33%), Positives = 42/78 (53%), Gaps = 5/78 (6%)
Query: 128 GQLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKKTKVARKSLDPLYNQVLLF 187
G LEV I +A+ LTA T + ++K YLL + K KT V +KS++P +N +F
Sbjct: 609 GILEVFIKEAKNLTAVKSGGTSDS-FVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMF 667
Query: 188 ----PESPQGKVLQVIVW 201
P+ + L++ +W
Sbjct: 668 SGIHPQDIKNVCLELTIW 685
>gi|20270305 synaptotagmin-like 5 isoform 1 [Homo sapiens]
Length = 730
Score = 45.4 bits (106), Expect = 5e-05
Identities = 32/115 (27%), Positives = 53/115 (46%), Gaps = 5/115 (4%)
Query: 126 RNGQLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKKTKVARKSLDPLYNQVL 185
+ G L + + R L K AY+K+YLL + K+KTK+ R +P +N+ L
Sbjct: 419 KTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKI-RTGTNPEFNETL 477
Query: 186 LFPESP---QGKVLQVIVWGNYGRMERKQFMGVARVLLEELDLTTLAVGWYKLFP 237
+ S + + LQ+ VW +Y R R F+G + + + W+ L P
Sbjct: 478 KYTISHTQLETRTLQLSVW-HYDRFGRNSFLGEVEIPFDSWNFENPTDEWFVLQP 531
Score = 42.4 bits (98), Expect = 4e-04
Identities = 26/78 (33%), Positives = 42/78 (53%), Gaps = 5/78 (6%)
Query: 128 GQLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKKTKVARKSLDPLYNQVLLF 187
G LEV I +A+ LTA T + ++K YLL + K KT V +KS++P +N +F
Sbjct: 587 GILEVFIKEAKNLTAVKSGGTSDS-FVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMF 645
Query: 188 ----PESPQGKVLQVIVW 201
P+ + L++ +W
Sbjct: 646 SGIHPQDIKNVCLELTIW 663
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,488,840
Number of Sequences: 37866
Number of extensions: 386787
Number of successful extensions: 975
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 50
Number of HSP's that attempted gapping in prelim test: 854
Number of HSP's gapped (non-prelim): 165
length of query: 269
length of database: 18,247,518
effective HSP length: 101
effective length of query: 168
effective length of database: 14,423,052
effective search space: 2423072736
effective search space used: 2423072736
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.