BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|33563374 carboxylesterase 3 [Homo sapiens] (571 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|33563374 carboxylesterase 3 [Homo sapiens] 1162 0.0 gi|37622885 carboxylesterase 2 isoform 1 [Homo sapiens] 483 e-136 gi|37622887 carboxylesterase 2 isoform 2 [Homo sapiens] 469 e-132 gi|219521907 carboxylesterase 7 isoform 1 [Homo sapiens] 452 e-127 gi|68508957 carboxylesterase 1 isoform c precursor [Homo sapiens] 451 e-127 gi|68508967 carboxylesterase 1 isoform a precursor [Homo sapiens] 451 e-126 gi|68508965 carboxylesterase 1 isoform b precursor [Homo sapiens] 450 e-126 gi|21450749 carboxylesterase 7 isoform 2 [Homo sapiens] 374 e-103 gi|115529439 carboxylesterase 8 (putative) [Homo sapiens] 337 1e-92 gi|51593088 neuroligin 3 [Homo sapiens] 285 8e-77 gi|31317256 X-linked neuroligin 4 [Homo sapiens] 283 3e-76 gi|24308209 X-linked neuroligin 4 [Homo sapiens] 283 3e-76 gi|30840978 neuroligin 2 [Homo sapiens] 282 5e-76 gi|7662470 neuroligin 1 [Homo sapiens] 282 7e-76 gi|40538788 neuroligin 4, Y-linked [Homo sapiens] 280 3e-75 gi|4557239 acetylcholinesterase isoform E4-E6 precursor [Homo sa... 264 1e-70 gi|7710112 acetylcholinesterase isoform E4-E5 precursor [Homo sa... 264 1e-70 gi|4557351 butyrylcholinesterase precursor [Homo sapiens] 235 9e-62 gi|148536848 carboxyl ester lipase precursor [Homo sapiens] 230 2e-60 gi|169216018 PREDICTED: similar to hCG40360 [Homo sapiens] 189 5e-48 gi|169215613 PREDICTED: similar to hCG40360 [Homo sapiens] 189 8e-48 gi|55770862 thyroglobulin [Homo sapiens] 185 1e-46 gi|239752162 PREDICTED: similar to hCG40360 [Homo sapiens] 111 2e-24 gi|61966717 arylacetamide deacetylase-like 4 [Homo sapiens] 35 0.14 gi|23510451 N-acylaminoacyl-peptide hydrolase [Homo sapiens] 34 0.41 gi|194394146 dipeptidylpeptidase 9 [Homo sapiens] 33 0.54 gi|16933557 dachsous 1 precursor [Homo sapiens] 32 1.6 gi|222352145 serine/threonine/tyrosine kinase 1 [Homo sapiens] 31 2.7 gi|84875539 phosphoribosyl pyrophosphate synthetase 2 isoform 1 ... 31 2.7 gi|4506129 phosphoribosyl pyrophosphate synthetase 2 isoform 2 [... 31 2.7 >gi|33563374 carboxylesterase 3 [Homo sapiens] Length = 571 Score = 1162 bits (3007), Expect = 0.0 Identities = 571/571 (100%), Positives = 571/571 (100%) Query: 1 MERAVRVESGVLVGVVCLLLACPATATGPEVAQPEVDTTLGRVRGRQVGVKGTDRLVNVF 60 MERAVRVESGVLVGVVCLLLACPATATGPEVAQPEVDTTLGRVRGRQVGVKGTDRLVNVF Sbjct: 1 MERAVRVESGVLVGVVCLLLACPATATGPEVAQPEVDTTLGRVRGRQVGVKGTDRLVNVF 60 Query: 61 LGIPFAQPPLGPDRFSAPHPAQPWEGVRDASTAPPMCLQDVESMNSSRFVLNGKQQIFSV 120 LGIPFAQPPLGPDRFSAPHPAQPWEGVRDASTAPPMCLQDVESMNSSRFVLNGKQQIFSV Sbjct: 61 LGIPFAQPPLGPDRFSAPHPAQPWEGVRDASTAPPMCLQDVESMNSSRFVLNGKQQIFSV 120 Query: 121 SEDCLVLNVYSPAEVPAGSGRPVMVWVHGGALITGAATSYDGSALAAYGDVVVVTVQYRL 180 SEDCLVLNVYSPAEVPAGSGRPVMVWVHGGALITGAATSYDGSALAAYGDVVVVTVQYRL Sbjct: 121 SEDCLVLNVYSPAEVPAGSGRPVMVWVHGGALITGAATSYDGSALAAYGDVVVVTVQYRL 180 Query: 181 GVLGFFSTGDEHAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVL 240 GVLGFFSTGDEHAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVL Sbjct: 181 GVLGFFSTGDEHAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVL 240 Query: 241 SPVAAGLFHRAITQSGVITTPGIIDSHPWPLAQKIANTLACSSSSPAEMVQCLQQKEGEE 300 SPVAAGLFHRAITQSGVITTPGIIDSHPWPLAQKIANTLACSSSSPAEMVQCLQQKEGEE Sbjct: 241 SPVAAGLFHRAITQSGVITTPGIIDSHPWPLAQKIANTLACSSSSPAEMVQCLQQKEGEE 300 Query: 301 LVLSKKLKNTIYPLTVDGTVFPKSPKELLKEKPFHSVPFLMGVNNHEFSWLIPRGWGLLD 360 LVLSKKLKNTIYPLTVDGTVFPKSPKELLKEKPFHSVPFLMGVNNHEFSWLIPRGWGLLD Sbjct: 301 LVLSKKLKNTIYPLTVDGTVFPKSPKELLKEKPFHSVPFLMGVNNHEFSWLIPRGWGLLD 360 Query: 361 TMEQMSREDMLAISTPVLTSLDVPPEMMPTVIDEYLGSNSDAQAKCQAFQEFMGDVFINV 420 TMEQMSREDMLAISTPVLTSLDVPPEMMPTVIDEYLGSNSDAQAKCQAFQEFMGDVFINV Sbjct: 361 TMEQMSREDMLAISTPVLTSLDVPPEMMPTVIDEYLGSNSDAQAKCQAFQEFMGDVFINV 420 Query: 421 PTVSFSRYLRDSGSPVFFYEFQHRPSSFAKIKPAWVKADHGAEGAFVFGGPFLMDESSRL 480 PTVSFSRYLRDSGSPVFFYEFQHRPSSFAKIKPAWVKADHGAEGAFVFGGPFLMDESSRL Sbjct: 421 PTVSFSRYLRDSGSPVFFYEFQHRPSSFAKIKPAWVKADHGAEGAFVFGGPFLMDESSRL 480 Query: 481 AFPEATEEEKQLSLTMMAQWTHFARTGDPNSKALPPWPQFNQAEQYLEINPVPRAGQKFR 540 AFPEATEEEKQLSLTMMAQWTHFARTGDPNSKALPPWPQFNQAEQYLEINPVPRAGQKFR Sbjct: 481 AFPEATEEEKQLSLTMMAQWTHFARTGDPNSKALPPWPQFNQAEQYLEINPVPRAGQKFR 540 Query: 541 EAWMQFWSETLPSKIQQWHQKQKNRKAQEDL 571 EAWMQFWSETLPSKIQQWHQKQKNRKAQEDL Sbjct: 541 EAWMQFWSETLPSKIQQWHQKQKNRKAQEDL 571 >gi|37622885 carboxylesterase 2 isoform 1 [Homo sapiens] Length = 623 Score = 483 bits (1242), Expect = e-136 Identities = 263/560 (46%), Positives = 347/560 (61%), Gaps = 23/560 (4%) Query: 12 LVGVVCLLLACPATATGPEVAQPEVDTTLGRVRGRQVGVKGTDRLVNVFLGIPFAQPPLG 71 L V C LL G + A P T G+V G V VKG + V FLGIPFA+PPLG Sbjct: 74 LSAVACGLLLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLG 133 Query: 72 PDRFSAPHPAQPWEGVRDASTAPPMCLQDVESMNS---SRFVLNGKQQIFSVSEDCLVLN 128 P RF+ P P + W GVRD +T P MCLQD+ ++ S S+F + S+SEDCL L+ Sbjct: 134 PLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSD--SMSEDCLYLS 191 Query: 129 VYSPAEVPAGSGRPVMVWVHGGALITGAATSYDGSALAAYGDVVVVTVQYRLGVLGFFST 188 +Y+PA GS PVMVW+HGGAL+ G A+ YDGS LAA +VVVV +QYRLGVLGFFST Sbjct: 192 IYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLGVLGFFST 251 Query: 189 GDEHAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLF 248 GD+HA GN G+LD VAALRWVQ+NIA FGG+ + VT+FG SAGG+ +S LV+SP++ GLF Sbjct: 252 GDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLF 311 Query: 249 HRAITQSGVITTPGIIDSHPWPLAQKIANTLACSSSSPAEMVQCLQQKEGEE-LVLSKKL 307 H AI +SGV PG+I S ++ +AN AC +V CL+ K EE L ++K Sbjct: 312 HGAIMESGVALLPGLIASSADVISTVVANLSACDQVDSEALVGCLRGKSKEEILAINKPF 371 Query: 308 KNTIYPLTVDGTVFPKSPKELLKEKPFHSVPFLMGVNNHEFSWLIPRGWGLLDTMEQMSR 367 K + P VDG P+ P+ELL F VP ++GVNN+EF WLIP+ + DT ++M R Sbjct: 372 K--MIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEMDR 429 Query: 368 EDMLAISTPVLTSLDVPPEMMPTVIDEYLGSNSDAQAKCQAFQEFMGDVFINVPTVSFSR 427 E A +LT L +PP + +EY+G N D Q FQE M D +P + + Sbjct: 430 EASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMFVIPALQVAH 489 Query: 428 YLRDSGSPVFFYEFQHRPSSFAKIKPAWVKADHGAEGAFV----FGGPFLMDESSRLAFP 483 + + S +PV+FYEFQH+PS I+P +KADHG E FV FGG ++ Sbjct: 490 F-QCSRAPVYFYEFQHQPSWLKNIRPPHMKADHGDELPFVFRSFFGGNYI---------- 538 Query: 484 EATEEEKQLSLTMMAQWTHFARTGDPNSKALPPWPQFNQAEQYLEINPVPRAGQKFREAW 543 + TEEE+QLS MM W +FAR G+PN + LP WP F+Q EQYL++N P G+ + Sbjct: 539 KFTEEEEQLSRKMMKYWANFARNGNPNGEGLPHWPLFDQEEQYLQLNLQPAVGRALKAHR 598 Query: 544 MQFWSETLPSKIQQWHQKQK 563 +QFW + LP KIQ+ + ++ Sbjct: 599 LQFWKKALPQKIQELEEPEE 618 >gi|37622887 carboxylesterase 2 isoform 2 [Homo sapiens] Length = 607 Score = 469 bits (1208), Expect = e-132 Identities = 256/556 (46%), Positives = 338/556 (60%), Gaps = 31/556 (5%) Query: 12 LVGVVCLLLACPATATGPEVAQPEVDTTLGRVRGRQVGVKGTDRLVNVFLGIPFAQPPLG 71 L V C LL G + A P T G+V G V VKG + V FLGIPFA+PPLG Sbjct: 74 LSAVACGLLLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLG 133 Query: 72 PDRFSAPHPAQPWEGVRDASTAPPMCLQDVESMNS---SRFVLNGKQQIFSVSEDCLVLN 128 P RF+ P P + W GVRD +T P MCLQD+ ++ S S+F + S+SEDCL L+ Sbjct: 134 PLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSD--SMSEDCLYLS 191 Query: 129 VYSPAEVPAGSGRPVMVWVHGGALITGAATSYDGSALAAYGDVVVVTVQYRLGVLGFFST 188 +Y+PA GS PVMVW+HGGAL+ G A+ YDGS LAA +VVVV +QYRLGVLGFFST Sbjct: 192 IYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLGVLGFFST 251 Query: 189 GDEHAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLF 248 GD+HA GN G+LD VAALRWVQ+NIA FGG+ + VT+FG SAGG+ +S LV+SP++ GLF Sbjct: 252 GDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLF 311 Query: 249 HRAITQSGVITTPGIIDSHPWPLAQKIANTLACSSSSPAEMVQCLQQKEGEE-LVLSKKL 307 H AI +SGV PG+I S ++ +AN AC +V CL+ K EE L ++K Sbjct: 312 HGAIMESGVALLPGLIASSADVISTVVANLSACDQVDSEALVGCLRGKSKEEILAINKPF 371 Query: 308 KNTIYPLTVDGTVFPKSPKELLKEKPFHSVPFLMGVNNHEFSWLIPRGWGLLDTMEQMSR 367 K + P VDG P+ P+ELL F VP ++GVNN+EF WLIP+ + DT ++M R Sbjct: 372 K--MIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEMDR 429 Query: 368 EDMLAISTPVLTSLDVPPEMMPTVIDEYLGSNSDAQAKCQAFQEFMGDVFINVPTVSFSR 427 E A +LT L +PP + +EY+G N D Q FQE M D +P + + Sbjct: 430 EASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMFVIPALQVAH 489 Query: 428 YLRDSGSPVFFYEFQHRPSSFAKIKPAWVKADHGAEGAFVFGGPFLMDESSRLAFPEATE 487 + + S +PV+FYEFQH+PS I+P +KADH + TE Sbjct: 490 F-QCSRAPVYFYEFQHQPSWLKNIRPPHMKADH----------------------VKFTE 526 Query: 488 EEKQLSLTMMAQWTHFARTGDPNSKALPPWPQFNQAEQYLEINPVPRAGQKFREAWMQFW 547 EE+QLS MM W +FAR G+PN + LP WP F+Q EQYL++N P G+ + +QFW Sbjct: 527 EEEQLSRKMMKYWANFARNGNPNGEGLPHWPLFDQEEQYLQLNLQPAVGRALKAHRLQFW 586 Query: 548 SETLPSKIQQWHQKQK 563 + LP KIQ+ + ++ Sbjct: 587 KKALPQKIQELEEPEE 602 >gi|219521907 carboxylesterase 7 isoform 1 [Homo sapiens] Length = 575 Score = 452 bits (1164), Expect = e-127 Identities = 241/533 (45%), Positives = 334/533 (62%), Gaps = 13/533 (2%) Query: 24 ATATGPEVAQPEVDTTLGRVRGRQVGVKGTDRLVNVFLGIPFAQPPLGPDRFSAPHPAQP 83 A GP P+ +T LG ++G+QV V G+ VNVFLG+PFA PPLG RF+ P PA P Sbjct: 21 APTKGPSAEGPQRNTRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPASP 80 Query: 84 WEGVRDASTAPPMCLQDVESMNSSRFVLNGKQQIFSVSEDCLVLNVYSPAEVPAGSGRPV 143 W+ +R+A++ P +CLQ+ E + + +L F VSEDCL LN+Y+PA GS PV Sbjct: 81 WDNLREATSYPNLCLQNSEWLLLDQHMLKVHYPKFGVSEDCLYLNIYAPAHADTGSKLPV 140 Query: 144 MVWVHGGALITGAATSYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVV 203 +VW GGA TG+A+ +DGSALAAY DV+VV VQYRLG+ GFF+T D+HAPGN F D V Sbjct: 141 LVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQV 200 Query: 204 AALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQSGVITTPGI 263 AAL WVQ+NI FGGD + VT+FG SAG +S L+LSP+A GLFH+AI +SGV P Sbjct: 201 AALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAIIP-Y 259 Query: 264 IDSHPWPLA---QKIANTLACSSSSPAEMVQCLQQKEGEELV-LSKKLKNTIYPLTVDGT 319 +++H + + Q +A+ ++S +++CL+ K +EL+ LS+K K+ + VDG Sbjct: 260 LEAHDYEKSEDLQVVAHFCGNNASDSEALLRCLRTKPSKELLTLSQKTKS--FTRVVDGA 317 Query: 320 VFPKSPKELLKEKPFHSVPFLMGVNNHEFSWLIPRGWGLLDTMEQMSREDMLAISTPVLT 379 FP P +LL +K F ++P ++GVNNHE +L+P + + E +S + + Sbjct: 318 FFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLP----MKEAPEILSGSNKSLALHLIQN 373 Query: 380 SLDVPPEMMPTVIDEYLGSNSDAQAKCQAFQEFMGDVFINVPTVSFSRYLRDSGSPVFFY 439 L +PP+ + V +EY + + +GDVF VP + +RY RD+G+PV+FY Sbjct: 374 ILHIPPQYLHLVANEYFHDKHSLTEIRDSLLDLLGDVFFVVPALITARYHRDAGAPVYFY 433 Query: 440 EFQHRPSSFAKIKPAWVKADHGAEGAFVFGGPFLMDESSRLAFPEATEEEKQLSLTMMAQ 499 EF+HRP F KPA+VKADH E FVFGG FL + + F ATEEEK LS MM Sbjct: 434 EFRHRPQCFEDTKPAFVKADHADEVRFVFGGAFL--KGDIVMFEGATEEEKLLSRKMMKY 491 Query: 500 WTHFARTGDPNSKALPPWPQFNQAEQYLEINPVPRAGQKFREAWMQFWSETLP 552 W FARTG+PN L WP +N EQYL+++ GQ+ +E + FW+ T+P Sbjct: 492 WATFARTGNPNGNDLSLWPAYNLTEQYLQLDLNMSLGQRLKEPRVDFWTSTIP 544 >gi|68508957 carboxylesterase 1 isoform c precursor [Homo sapiens] Length = 566 Score = 451 bits (1160), Expect = e-127 Identities = 242/548 (44%), Positives = 342/548 (62%), Gaps = 25/548 (4%) Query: 24 ATATGPEVAQPEVDTTLGRVRGRQVGVKGTDRLVNVFLGIPFAQPPLGPDRFSAPHPAQP 83 + A G + P VDT G+V G+ V ++G + V +FLGIPFA+PPLGP RF+ P PA+P Sbjct: 14 SAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEP 73 Query: 84 WEGVRDASTAPPMCLQDVESMNS-SRFVLNGKQQI-FSVSEDCLVLNVYSPAEVPAGSGR 141 W V++A++ PPMC QD ++ S N K+ I +SEDCL LN+Y+PA++ + Sbjct: 74 WSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNRL 133 Query: 142 PVMVWVHGGALITGAATSYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLD 201 PVMVW+HGG L+ GAA++YDG ALAA+ +VVVVT+QYRLG+ GFFSTGDEH+ GN G LD Sbjct: 134 PVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLD 193 Query: 202 VVAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQSGVITTP 261 VAALRWVQ+NIA FGG+ VT+FG SAGG +S LVLSP+A LFHRAI++SGV T Sbjct: 194 QVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTS 253 Query: 262 GII-DSHPWPLAQKIANTLACSSSSPAEMVQCLQQKEGEELV-LSKKLK----------- 308 ++ PLA++IA T C +++ A MV CL+QK EEL+ + K+K Sbjct: 254 VLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPR 313 Query: 309 --NTIYPLTVDGTVFPKSPKELLKEKPFHSVPFLMGVNNHEFSWLIPRGWGLLDTMEQMS 366 + +DG + K+P+EL E+ FH+VP+++G+N EF WLIP + Q+ Sbjct: 314 ESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMLMSYPLSEGQLD 373 Query: 367 REDMLAISTPVLTSLDVPPEMMPTVIDEYLGSNSDAQAKCQAFQEFMGDVFINVPTVSFS 426 ++ +++ + + E++P ++YLG D K F + + DV VP+V + Sbjct: 374 QKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVA 433 Query: 427 RYLRDSGSPVFFYEFQHRPSSFAKIKPAWVKADHGAEGAFVFGGPFLMDESSRLAFPEAT 486 R RD+G+P + YEFQ+RPS + +KP V DHG E VFG PFL + A+ Sbjct: 434 RNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKE--------GAS 485 Query: 487 EEEKQLSLTMMAQWTHFARTGDPNSKALPPWPQFNQAEQYLEINPVPRAGQKFREAWMQF 546 EEE +LS +M W +FAR G+PN + LP WP++NQ E YL+I +A QK ++ + F Sbjct: 486 EEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKDKEVAF 545 Query: 547 WSETLPSK 554 W+ K Sbjct: 546 WTNLFAKK 553 >gi|68508967 carboxylesterase 1 isoform a precursor [Homo sapiens] Length = 568 Score = 451 bits (1159), Expect = e-126 Identities = 250/559 (44%), Positives = 345/559 (61%), Gaps = 38/559 (6%) Query: 20 LACPATATGPEVAQPEVDTTLGRVRGRQVGVKGTDRLVNVFLGIPFAQPPLGPDRFSAPH 79 L+ A G + P VDT G+V G+ V ++G + V +FLGIPFA+PPLGP RF+ P Sbjct: 11 LSASAAWAGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQ 70 Query: 80 PAQPWEGVRDASTAPPMCLQDVESMNS-SRFVLNGKQQI-FSVSEDCLVLNVYSPAEVPA 137 PA+PW V++A++ PPMC QD ++ S N K+ I +SEDCL LN+Y+PA++ Sbjct: 71 PAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTK 130 Query: 138 GSGRPVMVWVHGGALITGAATSYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQ 197 + PVMVW+HGG L+ GAA++YDG ALAA+ +VVVVT+QYRLG+ GFFSTGDEH+ GN Sbjct: 131 KNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNW 190 Query: 198 GFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQSGV 257 G LD VAALRWVQ+NIA FGG+ VT+FG SAGG +S LVLSP+A LFHRAI++SGV Sbjct: 191 GHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGV 250 Query: 258 ITTPGII-DSHPWPLAQKIANTLACSSSSPAEMVQCLQQKEGEELV-LSKKLK------- 308 T ++ PLA++IA T C +++ A MV CL+QK EEL+ + K+K Sbjct: 251 ALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQ 310 Query: 309 ------NTIYPLTVDGTVFPKSPKELLKEKPFHSVPFLMGVNNHEFSWLIPR-------G 355 + +DG + K+P+EL E+ FH+VP+++G+N EF WLIP Sbjct: 311 GDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLS 370 Query: 356 WGLLDTMEQMSREDMLAISTPVLTSLDVPPEMMPTVIDEYLGSNSDAQAKCQAFQEFMGD 415 G LD MS +L S P++ + E++P ++YLG D K F + + D Sbjct: 371 EGQLDQKTAMS---LLWKSYPLVC---IAKELIPEATEKYLGGTDDTVKKKDLFLDLIAD 424 Query: 416 VFINVPTVSFSRYLRDSGSPVFFYEFQHRPSSFAKIKPAWVKADHGAEGAFVFGGPFLMD 475 V VP+V +R RD+G+P + YEFQ+RPS + +KP V DHG E VFG PFL + Sbjct: 425 VMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKE 484 Query: 476 ESSRLAFPEATEEEKQLSLTMMAQWTHFARTGDPNSKALPPWPQFNQAEQYLEINPVPRA 535 A+EEE +LS +M W +FAR G+PN + LP WP++NQ E YL+I +A Sbjct: 485 --------GASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQA 536 Query: 536 GQKFREAWMQFWSETLPSK 554 QK ++ + FW+ K Sbjct: 537 AQKLKDKEVAFWTNLFAKK 555 >gi|68508965 carboxylesterase 1 isoform b precursor [Homo sapiens] Length = 567 Score = 450 bits (1157), Expect = e-126 Identities = 249/555 (44%), Positives = 344/555 (61%), Gaps = 38/555 (6%) Query: 24 ATATGPEVAQPEVDTTLGRVRGRQVGVKGTDRLVNVFLGIPFAQPPLGPDRFSAPHPAQP 83 + A G + P VDT G+V G+ V ++G + V +FLGIPFA+PPLGP RF+ P PA+P Sbjct: 14 SAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEP 73 Query: 84 WEGVRDASTAPPMCLQDVESMNS-SRFVLNGKQQI-FSVSEDCLVLNVYSPAEVPAGSGR 141 W V++A++ PPMC QD ++ S N K+ I +SEDCL LN+Y+PA++ + Sbjct: 74 WSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNRL 133 Query: 142 PVMVWVHGGALITGAATSYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLD 201 PVMVW+HGG L+ GAA++YDG ALAA+ +VVVVT+QYRLG+ GFFSTGDEH+ GN G LD Sbjct: 134 PVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLD 193 Query: 202 VVAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQSGVITTP 261 VAALRWVQ+NIA FGG+ VT+FG SAGG +S LVLSP+A LFHRAI++SGV T Sbjct: 194 QVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTS 253 Query: 262 GII-DSHPWPLAQKIANTLACSSSSPAEMVQCLQQKEGEELV-LSKKLK----------- 308 ++ PLA++IA T C +++ A MV CL+QK EEL+ + K+K Sbjct: 254 VLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPR 313 Query: 309 --NTIYPLTVDGTVFPKSPKELLKEKPFHSVPFLMGVNNHEFSWLIPR-------GWGLL 359 + +DG + K+P+EL E+ FH+VP+++G+N EF WLIP G L Sbjct: 314 ESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQL 373 Query: 360 DTMEQMSREDMLAISTPVLTSLDVPPEMMPTVIDEYLGSNSDAQAKCQAFQEFMGDVFIN 419 D MS +L S P++ + E++P ++YLG D K F + + DV Sbjct: 374 DQKTAMS---LLWKSYPLVC---IAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFG 427 Query: 420 VPTVSFSRYLRDSGSPVFFYEFQHRPSSFAKIKPAWVKADHGAEGAFVFGGPFLMDESSR 479 VP+V +R RD+G+P + YEFQ+RPS + +KP V DHG E VFG PFL + Sbjct: 428 VPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKE---- 483 Query: 480 LAFPEATEEEKQLSLTMMAQWTHFARTGDPNSKALPPWPQFNQAEQYLEINPVPRAGQKF 539 A+EEE +LS +M W +FAR G+PN + LP WP++NQ E YL+I +A QK Sbjct: 484 ----GASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKL 539 Query: 540 REAWMQFWSETLPSK 554 ++ + FW+ K Sbjct: 540 KDKEVAFWTNLFAKK 554 >gi|21450749 carboxylesterase 7 isoform 2 [Homo sapiens] Length = 525 Score = 374 bits (960), Expect = e-103 Identities = 212/533 (39%), Positives = 299/533 (56%), Gaps = 63/533 (11%) Query: 24 ATATGPEVAQPEVDTTLGRVRGRQVGVKGTDRLVNVFLGIPFAQPPLGPDRFSAPHPAQP 83 A GP P+ +T LG ++G+QV V G+ VNVFLG+PFA PPLG RF+ P PA P Sbjct: 21 APTKGPSAEGPQRNTRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPASP 80 Query: 84 WEGVRDASTAPPMCLQDVESMNSSRFVLNGKQQIFSVSEDCLVLNVYSPAEVPAGSGRPV 143 W+ +R+A++ P +CLQ+ E + + +L F VSEDCL LN+Y+PA GS PV Sbjct: 81 WDNLREATSYPNLCLQNSEWLLLDQHMLKVHYPKFGVSEDCLYLNIYAPAHADTGSKLPV 140 Query: 144 MVWVHGGALITGAATSYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVV 203 +VW GGA TG+A+ +DGSALAAY DV+VV VQYRLG+ GFF+T D+HAPGN F D V Sbjct: 141 LVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQV 200 Query: 204 AALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQSGVITTPGI 263 AAL WVQ+NI FGGD + VT+FG SAG +S L+LSP+A GLFH+AI +SGV P Sbjct: 201 AALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAIIP-Y 259 Query: 264 IDSHPWPLA---QKIANTLACSSSSPAEMVQCLQQKEGEELV-LSKKLKNTIYPLTVDGT 319 +++H + + Q +A+ ++S +++CL+ K +EL+ LS+K K+ + VDG Sbjct: 260 LEAHDYEKSEDLQVVAHFCGNNASDSEALLRCLRTKPSKELLTLSQKTKS--FTRVVDGA 317 Query: 320 VFPKSPKELLKEKPFHSVPFLMGVNNHEFSWLIPRGWGLLDTMEQMSREDMLAISTPVLT 379 FP P +LL +K F ++P ++GVNNHE +L+P + + E +S + + Sbjct: 318 FFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLP----MKEAPEILSGSNKSLALHLIQN 373 Query: 380 SLDVPPEMMPTVIDEYLGSNSDAQAKCQAFQEFMGDVFINVPTVSFSRYLRDSGSPVFFY 439 L +PP+ + V +EY + + +GDVF VP + +RY R+ Sbjct: 374 ILHIPPQYLHLVANEYFHDKHSLTEIRDSLLDLLGDVFFVVPALITARYHREG------- 426 Query: 440 EFQHRPSSFAKIKPAWVKADHGAEGAFVFGGPFLMDESSRLAFPEATEEEKQLSLTMMAQ 499 ATEEEK LS MM Sbjct: 427 ---------------------------------------------ATEEEKLLSRKMMKY 441 Query: 500 WTHFARTGDPNSKALPPWPQFNQAEQYLEINPVPRAGQKFREAWMQFWSETLP 552 W FARTG+PN L WP +N EQYL+++ GQ+ +E + FW+ T+P Sbjct: 442 WATFARTGNPNGNDLSLWPAYNLTEQYLQLDLNMSLGQRLKEPRVDFWTSTIP 494 >gi|115529439 carboxylesterase 8 (putative) [Homo sapiens] Length = 491 Score = 337 bits (865), Expect = 1e-92 Identities = 206/539 (38%), Positives = 287/539 (53%), Gaps = 98/539 (18%) Query: 33 QPEVDTTLGRVRGRQVGVKGTDRLVNVFLGIPFAQPPLGPDRFSAPHPAQPWEGVRDAST 92 +P+V T G ++G+Q+ V T + VFLG+PF++PPLG RF+ P P +PW+G+RDA+T Sbjct: 26 RPQVVTKYGTLQGKQMHVGKTP--IQVFLGVPFSRPPLGILRFAPPEPPEPWKGIRDATT 83 Query: 93 APPMCLQDVESMNSSRFVLNGKQ-QIFSVSEDCLVLNVYSPAEVPAGSGRPVMVWVHGGA 151 PP CLQ+ +S +V ++ + SEDCL LNVY+PA P PVMVW GGA Sbjct: 84 YPPGCLQESWGQLASMYVSTRERYKWLRFSEDCLYLNVYAPARAPGDPQLPVMVWFPGGA 143 Query: 152 LITGAATSYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVVAALRWVQE 211 I GAA+SY+GS LAA VV+V +Q+RLG+ GF ST D HA GN G LD +AALRWVQE Sbjct: 144 FIVGAASSYEGSDLAAREKVVLVFLQHRLGIFGFLSTDDSHARGNWGLLDQMAALRWVQE 203 Query: 212 NIAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQSGVITTPGIIDSHPWPL 271 NIA FGGD VT+FG SAG ISGL++SP+A+GLFHRAI+QSG I S+P + Sbjct: 204 NIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLFHRAISQSGTALFRLFITSNPLKV 263 Query: 272 AQKIANTLACSSSSPAEMVQCLQQKEGEELV-LSKKLK-----------NTIYPLT--VD 317 A+K+A+ C+ +S +V CL+ G +++ +S K++ I+ ++ VD Sbjct: 264 AKKVAHLAGCNHNSTQILVNCLRALSGTKVMRVSNKMRFLQLNFQRDPEEIIWSMSPVVD 323 Query: 318 GTVFPKSPKELLKEKPFHSVPFLMGVNNHEFSWLIPRGWGLLDTMEQMSREDMLAISTPV 377 G V P P LL + SVP+L+GVNN EF+WL+P Sbjct: 324 GVVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWLLP------------------------ 359 Query: 378 LTSLDVPPEMMPTVIDEYLGSNSDAQAKC--QAFQEFMGDVFINVPTVSFSRYLRDSGSP 435 ++ E +P V++EYL + ++ K + + D T+ + Y Sbjct: 360 ---YNITKEQVPLVVEEYLDNVNEHDWKMLRNRMMDIVQDATFVYATLQTAHY------- 409 Query: 436 VFFYEFQHRPSSFAKIKPAWVKADHGAEGAFVFGGPFLMDESSRLAFPEATEEEKQLSLT 495 HR S K EK LSL Sbjct: 410 -------HRGLSMGK--------------------------------------EKALSLQ 424 Query: 496 MMAQWTHFARTGDPNSKALPPWPQFNQAEQYLEINPVPRAGQKFREAWMQFWSETLPSK 554 MM W +FARTG+PN LP WP++N+ E+YL+++ R G K +E M FW S+ Sbjct: 425 MMKYWANFARTGNPNDGNLPCWPRYNKDEKYLQLDFTTRVGMKLKEKKMAFWMSLYQSQ 483 >gi|51593088 neuroligin 3 [Homo sapiens] Length = 828 Score = 285 bits (729), Expect = 8e-77 Identities = 197/594 (33%), Positives = 290/594 (48%), Gaps = 72/594 (12%) Query: 18 LLLACPATATGPEVAQPEVDTTLGRVRGRQVGVKGTDR-LVNVFLGIPFAQPPLGPDRFS 76 L LA A+ P P V+T G++RG +V + V+ +LG+P+A PP+G RF Sbjct: 29 LSLALRASTQAPA---PTVNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPPIGEKRFL 85 Query: 77 APHPAQPWEGVRDASTAPPMCLQDV-----ESMNSSRFVLN---GKQQIFSVSEDCLVLN 128 P P W G+R+A+ PP+C Q++ E M F N I +EDCL LN Sbjct: 86 PPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLN 145 Query: 129 VYSPAEVPAGS----------------------GRPVMVWVHGGALITGAATSYDGSALA 166 VY P E +G+ +PVMV++HGG+ + G DGS LA Sbjct: 146 VYVPTEDGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSILA 205 Query: 167 AYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVF 226 +YG+V+V+T+ YR+GVLGF STGD+ A GN G LD + ALRWV ENIA FGGD +TVF Sbjct: 206 SYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVF 265 Query: 227 GGSAGGSIISGLVLSPVAAGLFHRAITQSGVITTPGIIDSHPWPLAQKIANTLACSSSSP 286 G G S +S L LS + GLF RAI QSG + ++ P +A+ + C+ Sbjct: 266 GSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDT 325 Query: 287 AEMVQCLQQKEGEELV---LSKKLKNTIYPLTVDGTVFPKSPKELLKEKPFHSVPFLMGV 343 +MV CL+QK +ELV + + + +DG V P P+ L+++ F + ++GV Sbjct: 326 VDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIPDDPEILMEQGEFLNYDIMLGV 385 Query: 344 NNHEFSWLIPRGWGLLDTMEQMSREDMLAISTPVLTSLDVPPEMMPTVID-------EYL 396 N E + G++D + +S D + + +L PE T+ + ++ Sbjct: 386 NQGEGLKFVE---GVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWA 442 Query: 397 GSNSDAQAKCQAFQEFMGDVFINVPTVSFSRYLRDSGSPVFFYEFQHRPSSFAKIKPAWV 456 ++ + F ++ V+ + R GSP +FY F H S +KPAW Sbjct: 443 DRDNPETRRKTLVALFTDHQWVEPSVVTADLHAR-YGSPTYFYAFYHHCQSL--MKPAWS 499 Query: 457 KADHGAEGAFVFGGPFLMDESSRLAFP-EATEEEKQLSLTMMAQWTHFARTGDPNSKALP 515 A HG E +VFG P + FP ++ + LS +M WT+FA+TGDPN K +P Sbjct: 500 DAAHGDEVPYVFGVPMVGPTD---LFPCNFSKNDVMLSAVVMTYWTNFAKTGDPN-KPVP 555 Query: 516 ----------------PWPQFNQAEQ-YLEINPVPRAGQKFREAWMQFWSETLP 552 W ++N +Q YL I PR +R + FW +P Sbjct: 556 QDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHLVP 609 >gi|31317256 X-linked neuroligin 4 [Homo sapiens] Length = 816 Score = 283 bits (724), Expect = 3e-76 Identities = 186/592 (31%), Positives = 289/592 (48%), Gaps = 59/592 (9%) Query: 5 VRVESGVLVGVVCLLLACPATATGPEVAQPEVDTTLGRVRGRQVGVKGTDR-LVNVFLGI 63 V + S VL+ + L A T + P V+T G++RG + + V +LG+ Sbjct: 19 VMLNSNVLLWLTAL--AIKFTLIDSQAQYPVVNTNYGKIRGLRTPLPNEILGPVEQYLGV 76 Query: 64 PFAQPPLGPDRFSAPHPAQPWEGVRDASTAPPMCLQDVESMNSSRFVL---------NGK 114 P+A PP G RF P P W G+R+ + +C Q ++ + +L Sbjct: 77 PYASPPTGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLLHDMLPIWFTANLDTLM 136 Query: 115 QQIFSVSEDCLVLNVYSPAEVPA---GSGRPVMVWVHGGALITGAATSYDGSALAAYGDV 171 + +EDCL LN+Y P E S +PVMV++HGG+ + G DGS LA+YG+V Sbjct: 137 TYVQDQNEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNV 196 Query: 172 VVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAG 231 +V+T+ YRLG+LGF STGD+ A GN G LD + ALRW++EN+ FGGD VT+FG AG Sbjct: 197 IVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAG 256 Query: 232 GSIISGLVLSPVAAGLFHRAITQSGVITTPGIIDSHPWPLAQKIANTLACSSSSPAEMVQ 291 S +S L LS + GLF +AI QSG + ++ P + +A+ + C+ +MV+ Sbjct: 257 ASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVE 316 Query: 292 CLQQKEGEELVLSKKLKNTIYPLT--------VDGTVFPKSPKELLKEKPFHSVPFLMGV 343 CL+ K +EL+ + TI P T +DG V P P+ L+++ F + ++GV Sbjct: 317 CLRNKNYKELI-----QQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGV 371 Query: 344 NNHEFSWLIPRGWGLLDTMEQMSREDMLAISTPVLTSLDVPPEMMPTVIDEY------LG 397 N E + G++D + ++ D + + +L PE T+ + Sbjct: 372 NQGEGLKFVD---GIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWA 428 Query: 398 SNSDAQAKCQAFQEFMGDVFINVPTVSFSRYLRDSGSPVFFYEFQHRPSSFAKIKPAWVK 457 + + + + D P V+ + GSP +FY F H S ++KP+W Sbjct: 429 DKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQS--EMKPSWAD 486 Query: 458 ADHGAEGAFVFGGPFLMDESSRLAFPEATEEEKQLSLTMMAQWTHFARTGDPNSKALP-- 515 + HG E +VFG P M + L ++ + LS +M WT+FA+TGDPN + +P Sbjct: 487 SAHGDEVPYVFGIP--MIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPN-QPVPQD 543 Query: 516 --------------PWPQFNQAEQ-YLEINPVPRAGQKFREAWMQFWSETLP 552 W ++N +Q YL I PR +R + FW E +P Sbjct: 544 TKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVP 595 >gi|24308209 X-linked neuroligin 4 [Homo sapiens] Length = 816 Score = 283 bits (724), Expect = 3e-76 Identities = 186/592 (31%), Positives = 289/592 (48%), Gaps = 59/592 (9%) Query: 5 VRVESGVLVGVVCLLLACPATATGPEVAQPEVDTTLGRVRGRQVGVKGTDR-LVNVFLGI 63 V + S VL+ + L A T + P V+T G++RG + + V +LG+ Sbjct: 19 VMLNSNVLLWLTAL--AIKFTLIDSQAQYPVVNTNYGKIRGLRTPLPNEILGPVEQYLGV 76 Query: 64 PFAQPPLGPDRFSAPHPAQPWEGVRDASTAPPMCLQDVESMNSSRFVL---------NGK 114 P+A PP G RF P P W G+R+ + +C Q ++ + +L Sbjct: 77 PYASPPTGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLLHDMLPIWFTANLDTLM 136 Query: 115 QQIFSVSEDCLVLNVYSPAEVPA---GSGRPVMVWVHGGALITGAATSYDGSALAAYGDV 171 + +EDCL LN+Y P E S +PVMV++HGG+ + G DGS LA+YG+V Sbjct: 137 TYVQDQNEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNV 196 Query: 172 VVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAG 231 +V+T+ YRLG+LGF STGD+ A GN G LD + ALRW++EN+ FGGD VT+FG AG Sbjct: 197 IVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAG 256 Query: 232 GSIISGLVLSPVAAGLFHRAITQSGVITTPGIIDSHPWPLAQKIANTLACSSSSPAEMVQ 291 S +S L LS + GLF +AI QSG + ++ P + +A+ + C+ +MV+ Sbjct: 257 ASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVE 316 Query: 292 CLQQKEGEELVLSKKLKNTIYPLT--------VDGTVFPKSPKELLKEKPFHSVPFLMGV 343 CL+ K +EL+ + TI P T +DG V P P+ L+++ F + ++GV Sbjct: 317 CLRNKNYKELI-----QQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGV 371 Query: 344 NNHEFSWLIPRGWGLLDTMEQMSREDMLAISTPVLTSLDVPPEMMPTVIDEY------LG 397 N E + G++D + ++ D + + +L PE T+ + Sbjct: 372 NQGEGLKFVD---GIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWA 428 Query: 398 SNSDAQAKCQAFQEFMGDVFINVPTVSFSRYLRDSGSPVFFYEFQHRPSSFAKIKPAWVK 457 + + + + D P V+ + GSP +FY F H S ++KP+W Sbjct: 429 DKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQS--EMKPSWAD 486 Query: 458 ADHGAEGAFVFGGPFLMDESSRLAFPEATEEEKQLSLTMMAQWTHFARTGDPNSKALP-- 515 + HG E +VFG P M + L ++ + LS +M WT+FA+TGDPN + +P Sbjct: 487 SAHGDEVPYVFGIP--MIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPN-QPVPQD 543 Query: 516 --------------PWPQFNQAEQ-YLEINPVPRAGQKFREAWMQFWSETLP 552 W ++N +Q YL I PR +R + FW E +P Sbjct: 544 TKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVP 595 >gi|30840978 neuroligin 2 [Homo sapiens] Length = 835 Score = 282 bits (722), Expect = 5e-76 Identities = 196/582 (33%), Positives = 283/582 (48%), Gaps = 80/582 (13%) Query: 34 PEVDTTLGRVRG--RQVGVKGTDRLVNVFLGIPFAQPPLGPDRFSAPHPAQPWEGVRDAS 91 P V+T GRVRG R++ + +V FLG+P+A PPLG RF P W GVR+A+ Sbjct: 42 PVVNTAYGRVRGVRRELNNEILGPVVQ-FLGVPYATPPLGARRFQPPEAPASWPGVRNAT 100 Query: 92 TAPPMCLQDVES-----MNSSRFVLN---GKQQIFSVSEDCLVLNVYSPAE--------- 134 T PP C Q++ M F N + + SEDCL LN+Y P E Sbjct: 101 TLPPACPQNLHGALPAIMLPVWFTDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLTKKRD 160 Query: 135 ----------VPAGSGRPVMVWVHGGALITGAATSYDGSALAAYGDVVVVTVQYRLGVLG 184 + +PVM+++HGG+ + G +DGS LAAYG+V+V T+ YRLGVLG Sbjct: 161 EATLNPPDTDIRDPGKKPVMLFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYRLGVLG 220 Query: 185 FFSTGDEHAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVLSPVA 244 F STGD+ A GN G LD + ALRW+ ENIA FGGD +T+FG AG S ++ L+LS + Sbjct: 221 FLSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHHS 280 Query: 245 AGLFHRAITQSGVITTPGIIDSHPWPLAQKIANTLACSSSSPAEMVQCLQQKEGEELV-- 302 GLF +AI QSG + ++ P + +A + C AE V+CL++K ELV Sbjct: 281 EGLFQKAIAQSGTAISSWSVNYQPLKYTRLLAAKVGCDREDSAEAVECLRRKPSRELVDQ 340 Query: 303 -LSKKLKNTIYPLTVDGTVFPKSPKELLKEKPFHSVPFLMGVNNHEFSWLIPRGWGLLDT 361 + + + VDG V P P+ L+++ F + L+GVN +G GL Sbjct: 341 DVQPARYHIAFGPVVDGDVVPDDPEILMQQGEFLNYDMLIGVN---------QGEGLKFV 391 Query: 362 MEQMSREDMLAISTPVLT-------------SLDVPPEMMPTVIDEYLGSNSDAQAKCQA 408 + ED ++ S T DV E + + ++ ++ + Sbjct: 392 EDSAESEDGVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRDNGEMRRKTL 451 Query: 409 FQEFMGDVFINVPTVSFSRYLRDSGSPVFFYEFQHRPSSFAKIKPAWVKADHGAEGAFVF 468 F ++ P V+ ++ D SPV+FY F H A+ +P W A HG E +VF Sbjct: 452 LALFTDHQWV-APAVATAKLHADYQSPVYFYTFYHHCQ--AEGRPEWADAAHGDELPYVF 508 Query: 469 GGPFLMDESSRLAFP-EATEEEKQLSLTMMAQWTHFARTGDPNSKALPP----------- 516 G P + + FP ++ + LS +M WT+FA+TGDPN + +P Sbjct: 509 GVPMV---GATDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPN-QPVPQDTKFIHTKPNR 564 Query: 517 -----WPQFNQAE-QYLEINPVPRAGQKFREAWMQFWSETLP 552 W +FN E QYL I PR +R + FW E +P Sbjct: 565 FEEVVWSKFNSKEKQYLHIGLKPRVRDNYRANKVAFWLELVP 606 >gi|7662470 neuroligin 1 [Homo sapiens] Length = 823 Score = 282 bits (721), Expect = 7e-76 Identities = 194/587 (33%), Positives = 291/587 (49%), Gaps = 62/587 (10%) Query: 17 CLLLACPATATGPEVAQPEVDTTLGRVRG--RQVGVKGTDRLVNVFLGIPFAQPPLGPDR 74 CLL A + + P V T G++RG +++ + ++ FLG+P+A PP G R Sbjct: 36 CLLQAGHVLSQKLDDVDPLVATNFGKIRGIKKELNNEILGPVIQ-FLGVPYAAPPTGERR 94 Query: 75 FSAPHPAQPWEGVRDASTAPPMCLQDV------ESMNSSRFVLN---GKQQIFSVSEDCL 125 F P P PW +R+A+ P+C Q++ E M F N + SEDCL Sbjct: 95 FQPPEPPSPWSDIRNATQFAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCL 154 Query: 126 VLNVYSPAEVP---AGSGRPVMVWVHGGALITGAATSYDGSALAAYGDVVVVTVQYRLGV 182 LN+Y P E +G +PVMV++HGG+ + G YDGS LA+YG+V+V+TV YRLGV Sbjct: 155 YLNIYVPTEDDIRDSGGPKPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGV 214 Query: 183 LGFFSTGDEHAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVLSP 242 LGF STGD+ A GN G LD++ ALRW ENI FGGD +TVFG AGGS ++ L LS Sbjct: 215 LGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSH 274 Query: 243 VA---------AGLFHRAITQSGVITTPGIIDSHPWPLAQKIANTLACSSSSPAEMVQCL 293 + GLF RAI QSG + + P A+ +A + C+ S E+V+CL Sbjct: 275 YSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARMLATKVGCNVSDTVELVECL 334 Query: 294 QQKEGEELV---LSKKLKNTIYPLTVDGTVFPKSPKELLKEKPFHSVPFLMGVNNHEFSW 350 Q+K +ELV + + + +DG V P P+ L+++ F + ++GVN E Sbjct: 335 QKKPYKELVDQDIQPARYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLK 394 Query: 351 LIPRGWGLLDTMEQMSREDM-LAISTPV------LTSLDVPPEMMPTVIDEYLGSNSDAQ 403 + ++D+ + +S D A+S V DV E + + ++ ++ Sbjct: 395 FVE---NIVDSDDGISASDFDFAVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRHNPET 451 Query: 404 AKCQAFQEFMGDVFINVPTVSFSRYLRDSGSPVFFYEFQHRPSSFAKIKPAWVKADHGAE 463 + F ++ P V+ + + GSP +FY F H + PAW A HG E Sbjct: 452 RRKTLLALFTDHQWV-APAVATADLHSNFGSPTYFYAFYHHCQT--DQVPAWADAAHGDE 508 Query: 464 GAFVFGGPFLMDESSRLAFP-EATEEEKQLSLTMMAQWTHFARTGDPNSKALP------- 515 +V G P + FP ++ + LS +M WT+FA+TGDPN + +P Sbjct: 509 VPYVLGIPMI---GPTELFPCNFSKNDVMLSAVVMTYWTNFAKTGDPN-QPVPQDTKFIH 564 Query: 516 ---------PWPQFNQAEQ-YLEINPVPRAGQKFREAWMQFWSETLP 552 W +++Q +Q YL I PR + +R + W E +P Sbjct: 565 TKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRANKVNLWLELVP 611 >gi|40538788 neuroligin 4, Y-linked [Homo sapiens] Length = 816 Score = 280 bits (715), Expect = 3e-75 Identities = 187/596 (31%), Positives = 291/596 (48%), Gaps = 67/596 (11%) Query: 5 VRVESGVLVGVVCLLLACPATATGPEVAQPEVDTTLGRVRGRQVGVKGTDR-LVNVFLGI 63 V + S VL+ + L A T + P V+T G+++G + + V +LG+ Sbjct: 19 VMLNSNVLLWITAL--AIKFTLIDSQAQYPVVNTNYGKIQGLRTPLPSEILGPVEQYLGV 76 Query: 64 PFAQPPLGPDRFSAPHPAQPWEGVRDASTAPPMCLQDVESMNSSRFVLNGKQQIFSVS-- 121 P+A PP G RF P W G+R+A+ +C Q ++ RF+L+ I+ + Sbjct: 77 PYASPPTGERRFQPPESPSSWTGIRNATQFSAVCPQHLDE----RFLLHDMLPIWFTTSL 132 Query: 122 -----------EDCLVLNVYSPAEVPA---GSGRPVMVWVHGGALITGAATSYDGSALAA 167 EDCL LN+Y P E S +PVMV++HGG+ + G DGS LA+ Sbjct: 133 DTLMTYVQDQNEDCLYLNIYVPMEDDIHEQNSKKPVMVYIHGGSYMEGTGNMIDGSILAS 192 Query: 168 YGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFG 227 YG+V+V+T+ RLG+LGF STGD+ A GN G LD + ALRW++EN+ FGGD VT+FG Sbjct: 193 YGNVIVITINCRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFG 252 Query: 228 GSAGGSIISGLVLSPVAAGLFHRAITQSGVITTPGIIDSHPWPLAQKIANTLACSSSSPA 287 AG S +S L LS + GLF +AI QSG + ++ P + +A+ + C+ Sbjct: 253 SGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTT 312 Query: 288 EMVQCLQQKEGEELVLSKKLKNTIYPLT--------VDGTVFPKSPKELLKEKPFHSVPF 339 +MV+CL+ K +EL+ + TI P T +DG V P P+ L+++ F + Sbjct: 313 DMVECLKNKNYKELI-----QQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDI 367 Query: 340 LMGVNNHEFSWLIPRGWGLLDTMEQMSREDMLAISTPVLTSLDVPPEMMPTVIDEY---- 395 ++GVN E + G++D + ++ D + + +L PE T+ + Sbjct: 368 MLGVNQGEGLKFVD---GIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMY 424 Query: 396 --LGSNSDAQAKCQAFQEFMGDVFINVPTVSFSRYLRDSGSPVFFYEFQHRPSSFAKIKP 453 + + + + D P V+ + GSP +FY F H S ++KP Sbjct: 425 TDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQS--EMKP 482 Query: 454 AWVKADHGAEGAFVFGGPFLMDESSRLAFPEATEEEKQLSLTMMAQWTHFARTGDPNSKA 513 +W + HG E +VFG P M + L ++ + LS +M WT+FA+TGDPN + Sbjct: 483 SWADSAHGDEVPYVFGIP--MIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPN-QP 539 Query: 514 LP----------------PWPQFNQAEQ-YLEINPVPRAGQKFREAWMQFWSETLP 552 +P W ++N +Q YL I PR +R + FW E +P Sbjct: 540 VPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVP 595 >gi|4557239 acetylcholinesterase isoform E4-E6 precursor [Homo sapiens] Length = 614 Score = 264 bits (675), Expect = 1e-70 Identities = 191/560 (34%), Positives = 280/560 (50%), Gaps = 41/560 (7%) Query: 19 LLACPATATGPEVAQPEVDTTLGRVRGRQVGVKGTDRLVNVFLGIPFAQPPLGPDRFSAP 78 LL A G E A+ V GR+RG ++ G V+ FLGIPFA+PP+GP RF P Sbjct: 24 LLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPGGP--VSAFLGIPFAEPPMGPRRFLPP 81 Query: 79 HPAQPWEGVRDASTAPPMCLQDVESMNSSRFVLNGKQQIFSVSEDCLVLNVYSPAEVPAG 138 P QPW GV DA+T +C Q V+++ +SEDCL LNV++P P Sbjct: 82 EPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPT- 140 Query: 139 SGRPVMVWVHGGALITGAATS--YDGSALAAYGDVVVVTVQYRLGVLGFFST-GDEHAPG 195 S PV+VW++GG +GA++ YDG L V+V++ YR+G GF + G APG Sbjct: 141 SPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPG 200 Query: 196 NQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQS 255 N G LD AL+WVQEN+A FGGD VT+FG SAG + + +LSP + GLFHRA+ QS Sbjct: 201 NVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQS 260 Query: 256 GVITTP----GIIDSHPWPLAQKIANTLAC----SSSSPAEMVQCLQQKEGEELV----- 302 G P G+ ++ A ++A+ + C + + E+V CL+ + + LV Sbjct: 261 GAPNGPWATVGMGEAR--RRATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWH 318 Query: 303 --LSKKLKNTIYPLTVDGTVFPKSPKELLKEKPFHSVPFLMGVNNHEFSWLIPRG--WGL 358 + + + VDG +P+ L+ FH + L+GV E S+ + G Sbjct: 319 VLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFS 378 Query: 359 LDTMEQMSREDMLA-ISTPVLTSLDVPPEMMPTVIDEYLGSNSDAQAKCQAFQEFMGDVF 417 D +SR + LA + V D+ E + ++L A+ + +A + +GD Sbjct: 379 KDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLR-EALSDVVGDHN 437 Query: 418 INVPTVSFSRYLRDSGSPVFFYEFQHRPSSFAKIKPAWVKADHGAEGAFVFGGPFLMDES 477 + P + L G+ V+ Y F+HR S+ + P W+ HG E F+FG P +D S Sbjct: 438 VVCPVAQLAGRLAAQGARVYAYVFEHRASTLS--WPLWMGVPHGYEIEFIFGIP--LDPS 493 Query: 478 SRLAFPEATEEEKQLSLTMMAQWTHFARTGDPN---SKALPPWPQFNQ-AEQYLEINPVP 533 T EEK + +M W +FARTGDPN P WP + A+QY+ ++ P Sbjct: 494 RNY-----TAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQYVSLDLRP 548 Query: 534 -RAGQKFREAWMQFWSETLP 552 + R FW+ LP Sbjct: 549 LEVRRGLRAQACAFWNRFLP 568 >gi|7710112 acetylcholinesterase isoform E4-E5 precursor [Homo sapiens] Length = 617 Score = 264 bits (675), Expect = 1e-70 Identities = 191/560 (34%), Positives = 280/560 (50%), Gaps = 41/560 (7%) Query: 19 LLACPATATGPEVAQPEVDTTLGRVRGRQVGVKGTDRLVNVFLGIPFAQPPLGPDRFSAP 78 LL A G E A+ V GR+RG ++ G V+ FLGIPFA+PP+GP RF P Sbjct: 24 LLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPGGP--VSAFLGIPFAEPPMGPRRFLPP 81 Query: 79 HPAQPWEGVRDASTAPPMCLQDVESMNSSRFVLNGKQQIFSVSEDCLVLNVYSPAEVPAG 138 P QPW GV DA+T +C Q V+++ +SEDCL LNV++P P Sbjct: 82 EPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPT- 140 Query: 139 SGRPVMVWVHGGALITGAATS--YDGSALAAYGDVVVVTVQYRLGVLGFFST-GDEHAPG 195 S PV+VW++GG +GA++ YDG L V+V++ YR+G GF + G APG Sbjct: 141 SPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPG 200 Query: 196 NQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQS 255 N G LD AL+WVQEN+A FGGD VT+FG SAG + + +LSP + GLFHRA+ QS Sbjct: 201 NVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQS 260 Query: 256 GVITTP----GIIDSHPWPLAQKIANTLAC----SSSSPAEMVQCLQQKEGEELV----- 302 G P G+ ++ A ++A+ + C + + E+V CL+ + + LV Sbjct: 261 GAPNGPWATVGMGEAR--RRATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWH 318 Query: 303 --LSKKLKNTIYPLTVDGTVFPKSPKELLKEKPFHSVPFLMGVNNHEFSWLIPRG--WGL 358 + + + VDG +P+ L+ FH + L+GV E S+ + G Sbjct: 319 VLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFS 378 Query: 359 LDTMEQMSREDMLA-ISTPVLTSLDVPPEMMPTVIDEYLGSNSDAQAKCQAFQEFMGDVF 417 D +SR + LA + V D+ E + ++L A+ + +A + +GD Sbjct: 379 KDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLR-EALSDVVGDHN 437 Query: 418 INVPTVSFSRYLRDSGSPVFFYEFQHRPSSFAKIKPAWVKADHGAEGAFVFGGPFLMDES 477 + P + L G+ V+ Y F+HR S+ + P W+ HG E F+FG P +D S Sbjct: 438 VVCPVAQLAGRLAAQGARVYAYVFEHRASTLS--WPLWMGVPHGYEIEFIFGIP--LDPS 493 Query: 478 SRLAFPEATEEEKQLSLTMMAQWTHFARTGDPN---SKALPPWPQFNQ-AEQYLEINPVP 533 T EEK + +M W +FARTGDPN P WP + A+QY+ ++ P Sbjct: 494 RNY-----TAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQYVSLDLRP 548 Query: 534 -RAGQKFREAWMQFWSETLP 552 + R FW+ LP Sbjct: 549 LEVRRGLRAQACAFWNRFLP 568 >gi|4557351 butyrylcholinesterase precursor [Homo sapiens] Length = 602 Score = 235 bits (599), Expect = 9e-62 Identities = 174/544 (31%), Positives = 264/544 (48%), Gaps = 41/544 (7%) Query: 36 VDTTLGRVRGRQVGVKGTDRLVNVFLGIPFAQPPLGPDRFSAPHPAQPWEGVRDASTAPP 95 + T G+VRG + V G V FLGIP+AQPPLG RF P W + +A+ Sbjct: 34 IATKNGKVRGMNLTVFGGT--VTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYAN 91 Query: 96 MCLQDVESMNSSRFVLNGKQQIFSVSEDCLVLNVYSPAEVPAGSGRPVMVWVHGGALITG 155 C Q+++ +SEDCL LNV+ PA P + V++W++GG TG Sbjct: 92 SCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNA--TVLIWIYGGGFQTG 149 Query: 156 AATS--YDGSALAAYGDVVVVTVQYRLGVLGFFST-GDEHAPGNQGFLDVVAALRWVQEN 212 ++ YDG LA V+VV++ YR+G LGF + G+ APGN G D AL+WVQ+N Sbjct: 150 TSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKN 209 Query: 213 IAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQSGVITTPGIIDS--HPWP 270 IA FGG+ VT+FG SAG + +S +LSP + LF RAI QSG P + S Sbjct: 210 IAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARN 269 Query: 271 LAQKIANTLACSSSSPAEMVQCLQQKEGEELVLSKKL-------KNTIYPLTVDGTVFPK 323 +A CS + E+++CL+ K+ +E++L++ + + TVDG Sbjct: 270 RTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTD 329 Query: 324 SPKELLKEKPFHSVPFLMGVNNHE-FSWLIPRGWGL-LDTMEQMSREDM---LAISTPVL 378 P LL+ F L+GVN E ++L+ G D ++R++ L I P + Sbjct: 330 MPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGV 389 Query: 379 TSLDVPPEMMPTVIDEYLGSNSDAQAK--CQAFQEFMGDVFINVPTVSFSRYLRDSGSPV 436 + +++ Y D + + +A + +GD P + F++ + G+ Sbjct: 390 SEFG-----KESILFHYTDWVDDQRPENYREALGDVVGDYNFICPALEFTKKFSEWGNNA 444 Query: 437 FFYEFQHRPSSFAKIKPAWVKADHGAEGAFVFGGPFLMDESSRLAFPEATEEEKQLSLTM 496 FFY F+HR S P W+ HG E FVFG P ++ T+ E+ LS ++ Sbjct: 445 FFYYFEHRSSKLP--WPEWMGVMHGYEIEFVFGLPLERRDN-------YTKAEEILSRSI 495 Query: 497 MAQWTHFARTGDPN--SKALPPWPQFNQAEQ-YLEIN-PVPRAGQKFREAWMQFWSETLP 552 + +W +FA+ G+PN WP F EQ YL +N R K R +FW+ P Sbjct: 496 VKRWANFAKYGNPNETQNNSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTSFFP 555 Query: 553 SKIQ 556 ++ Sbjct: 556 KVLE 559 >gi|148536848 carboxyl ester lipase precursor [Homo sapiens] Length = 756 Score = 230 bits (587), Expect = 2e-60 Identities = 182/577 (31%), Positives = 275/577 (47%), Gaps = 75/577 (12%) Query: 11 VLVGVVCLLLACPATATGPEVAQPEVDTTLGRVRG--RQVGVKGTDRLVNVFLGIPFAQP 68 V++G+ C C A A+ ++ V T G V G +++G+ G V++F GIPFA P Sbjct: 10 VVLGLTC----CWAVASAAKLGA--VYTEGGFVEGVNKKLGLLGDS--VDIFKGIPFAAP 61 Query: 69 PLGPDRFSAPHPAQPWEGVRDASTAPPMCLQDVESMNSSRFVLNGKQQIFSVSEDCLVLN 128 + P P W+G A CLQ + +S+ EDCL LN Sbjct: 62 TKALEN---PQPHPGWQGTLKAKNFKKRCLQATITQDSTYG-----------DEDCLYLN 107 Query: 129 VYSP-AEVPAGSGRPVMVWVHGGALITGAATS--------YDGSALAAYGDVVVVTVQYR 179 ++ P PVM+W++GGA + G+ YDG +A G+V+VVT YR Sbjct: 108 IWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYR 167 Query: 180 LGVLGFFSTGDEHAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLV 239 +G LGF STGD + PGN G D A+ WV+ NIA FGGD N +T+FG SAGG+ +S Sbjct: 168 VGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQT 227 Query: 240 LSPVAAGLFHRAITQSGVITTPGIIDSHPWPLAQKIANTLACSSSSPAEMVQCLQQKEGE 299 LSP GL RAI+QSGV +P +I +P A+K+A + C A M QCL+ + Sbjct: 228 LSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPR 287 Query: 300 ELVLSKK--LKNTIYPL--------TVDGTVFPKSPKELLKEKPFHSVPFLMGVNN---H 346 L L+ K L YP+ +DG P P L + ++ G NN H Sbjct: 288 ALTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLYANAA--DIDYIAGTNNMDGH 345 Query: 347 EFSWL-IPRGWGLLDTMEQMSREDMLAISTPVLTSLDVPPEMMPTVIDEYLGS---NSDA 402 F+ + +P + ++++ ED + + + + T D Y S + Sbjct: 346 IFASIDMP---AINKGNKKVTEEDFYKLVSEFTITKGL--RGAKTTFDVYTESWAQDPSQ 400 Query: 403 QAKCQAFQEFMGDVFINVPT-VSFSRYLRDSGS-PVFFYEFQHRPSSFAKIKPAWVKADH 460 + K + +F DV VPT ++ +++ ++ S + Y F H S + P WV ADH Sbjct: 401 ENKKKTVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSH--PSRMPVYPKWVGADH 458 Query: 461 GAEGAFVFGGPFLMDESSRLAFPEATEEEKQLSLTMMAQWTHFARTGDPN--SKALPP-W 517 + +VFG PF R +++ +S M+A WT+FA+TGDPN A+P W Sbjct: 459 ADDIQYVFGKPFATPTGYR-------PQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHW 511 Query: 518 -PQFNQAEQYLEINPVPRAG---QKFREAWMQFWSET 550 P + YLEI + + R ++++W+ T Sbjct: 512 EPYTTENSGYLEITKKMGSSSMKRSLRTNFLRYWTLT 548 >gi|169216018 PREDICTED: similar to hCG40360 [Homo sapiens] Length = 327 Score = 189 bits (481), Expect = 5e-48 Identities = 112/286 (39%), Positives = 164/286 (57%), Gaps = 11/286 (3%) Query: 149 GGALITGAATSYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVVAALRW 208 GGA TG+A+ +DGS+LAAY D++VV VQYRLG+ GFF+T D+HAPGN F D VAAL W Sbjct: 20 GGAFETGSASIFDGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSW 79 Query: 209 VQENIAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQSGVITTPGIIDSHP 268 VQ+NI FGGD + VT+FG S G +S L+LSP+A GLFH+A+ +SGV + +H Sbjct: 80 VQKNIEFFGGDPSSVTIFGESVGAISVSSLMLSPMAEGLFHKAVMESGVAIIL-YLKAHD 138 Query: 269 WPLA---QKIANTLACSSSSPAEMVQCLQQKEGEELV-LSKKLKNTIYPLTVDGTVFPKS 324 + + Q +A ++S ++CL+ K +EL+ LS+K K + VDG FP Sbjct: 139 YEKSEDLQVVAQFCGYNASDSEAPLRCLRTKSSKELLTLSQKTK--AFTQVVDGAFFPNE 196 Query: 325 PKELLKEKPFHSVPFLMGVNNHEFSWLIPRGWGLLDTMEQMSREDMLAISTPVLTSLDVP 384 P +LL +K F ++P ++GVNN E + +P + + E +S + L + Sbjct: 197 PLDLLSQKAFKAIPSIIGVNNPECGFPLP----MKEAPEILSGSNKSLALCLTQNILHIL 252 Query: 385 PEMMPTVIDEYLGSNSDAQAKCQAFQEFMGDVFINVPTVSFSRYLR 430 P + V EY + + +GDVF +P + +RY R Sbjct: 253 PNYLHLVAGEYFHDKHSLTEIRDSLLDLLGDVFFVIPKLITARYHR 298 >gi|169215613 PREDICTED: similar to hCG40360 [Homo sapiens] Length = 327 Score = 189 bits (479), Expect = 8e-48 Identities = 111/286 (38%), Positives = 164/286 (57%), Gaps = 11/286 (3%) Query: 149 GGALITGAATSYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVVAALRW 208 GGA TG+A+ +DGS+LAAY D++VV VQYRLG+ GFF+T D+HAPGN F D VAAL W Sbjct: 20 GGAFETGSASIFDGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSW 79 Query: 209 VQENIAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQSGVITTPGIIDSHP 268 VQ+NI FGGD + VT+FG S G +S L+LSP+A GLFH+A+ +SGV + +H Sbjct: 80 VQKNIEFFGGDPSSVTIFGESVGAISVSSLILSPMAEGLFHKAVMESGVAIIL-YLKAHD 138 Query: 269 WPLA---QKIANTLACSSSSPAEMVQCLQQKEGEELV-LSKKLKNTIYPLTVDGTVFPKS 324 + + Q +A ++S ++CL+ K +EL+ LS+K K + VDG FP Sbjct: 139 YEKSEDLQVVAQFCGYNASDSEAPLRCLRTKSSKELLTLSQKTK--AFTQVVDGAFFPNE 196 Query: 325 PKELLKEKPFHSVPFLMGVNNHEFSWLIPRGWGLLDTMEQMSREDMLAISTPVLTSLDVP 384 P +LL +K F ++P ++GVNN E + +P + + E +S + L + Sbjct: 197 PLDLLSQKAFKAIPSIIGVNNPECGFPLP----MKEAPEILSGSNKSLALCLTQNILHIL 252 Query: 385 PEMMPTVIDEYLGSNSDAQAKCQAFQEFMGDVFINVPTVSFSRYLR 430 P + V EY + + +GDVF +P + ++Y R Sbjct: 253 PNYLHLVAGEYFHDKHSLTEIRDSLLDLLGDVFFVIPKLITAQYHR 298 >gi|55770862 thyroglobulin [Homo sapiens] Length = 2768 Score = 185 bits (469), Expect = 1e-46 Identities = 177/563 (31%), Positives = 245/563 (43%), Gaps = 72/563 (12%) Query: 30 EVAQPEVD-TTLGRVRGRQVGVK-GTD-RLVNVFLGIPFAQPPLGPDRFSAPHPAQPWEG 86 E + P V +T GR+ GR ++ GT + V+ FLG+P+A PPL RF AP P W G Sbjct: 2195 EASVPSVPISTHGRLLGRSQAIQVGTSWKQVDQFLGVPYAAPPLAERRFQAPEPLN-WTG 2253 Query: 87 VRDASTAPPMCLQDVESMNSSRFVLNGKQQIFSVSEDCLVLNVYSPAEVPAGSGRPVMVW 146 DAS C Q ++S VSEDCL LNV+ P V + V+V+ Sbjct: 2254 SWDASKPRASCWQPGTRTSTSP----------GVSEDCLYLNVFIPQNVAPNAS--VLVF 2301 Query: 147 VHG--GALITGAATSYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVVA 204 H + + DGS LAA G+++VVT YR+GV GF S+G GN G LD VA Sbjct: 2302 FHNTMDREESEGWPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVA 2361 Query: 205 ALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAG--LFHRAITQSGVITTPG 262 AL WVQ +I FGGD V++ G + S +L+ A LF RA+ G +P Sbjct: 2362 ALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPA 2421 Query: 263 IIDSHPWPLAQKI--ANTLACSSSSPAEMVQCLQQKEGEEL-VLSKKLKNTIYPL----- 314 + SH Q I A ++C SS E+V CL+QK L KL P Sbjct: 2422 AVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFHYWGP 2481 Query: 315 TVDGTVFPKSPKELLKEKPFHSVPFLMGVNNHEFSWLIPRGWGLLDTMEQMSR-EDMLAI 373 +DG + P LK + V L+G + + LI R + E R A Sbjct: 2482 VIDGHFLREPPARALKRSLWVEVDLLIGSSQDD--GLINRAKAVKQFEESRGRTSSKTAF 2539 Query: 374 STPVLTSL-----DVPPEMMPTVIDEYLGSNSDAQAKCQAFQEFMGDVFINVPTVSF-SR 427 + SL D E T S D + +A + D FI P + S Sbjct: 2540 YQALQNSLGGEDSDARVEAAATWYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASA 2599 Query: 428 YLRDSGSPVFFYEFQHRPSSFAKIKPAWVKADHG-----AEGAFVFGGPFLMDESSRLAF 482 + + + VF Y H P ++ HG A+ F G PF + + Sbjct: 2600 WAKRARGNVFMY---HAPENYG----------HGSLELLADVQFALGLPFYPAYEGQFSL 2646 Query: 483 PEATEEEKQLSLTMMAQWTHFARTGDPN-----SKALP----PWPQF---NQAEQYLEIN 530 EEK LSL +M ++HF R+G+PN S+ +P PWP F E Y E + Sbjct: 2647 -----EEKSLSLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFS 2701 Query: 531 PVPRAGQKFREAWMQFWSETLPS 553 + Q ++A FWS+ + S Sbjct: 2702 ELLPNRQGLKKADCSFWSKYISS 2724 >gi|239752162 PREDICTED: similar to hCG40360 [Homo sapiens] Length = 131 Score = 111 bits (278), Expect = 2e-24 Identities = 53/90 (58%), Positives = 68/90 (75%) Query: 143 VMVWVHGGALITGAATSYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDV 202 V++W GGA TG+A+ +DGS+LAAY D++VV VQYRLG+ GFF+T D+HAPGN F D Sbjct: 20 VLLWFPGGAFETGSASIFDGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQ 79 Query: 203 VAALRWVQENIAPFGGDLNCVTVFGGSAGG 232 VAAL WVQ+NI FGGD + VT+F + G Sbjct: 80 VAALSWVQKNIEFFGGDPSSVTIFDAVSHG 109 >gi|61966717 arylacetamide deacetylase-like 4 [Homo sapiens] Length = 407 Score = 35.4 bits (80), Expect = 0.14 Identities = 30/106 (28%), Positives = 50/106 (47%), Gaps = 13/106 (12%) Query: 137 AGSGRPV--MVWVHGGALITGAATSYDG--SALAAYGDVVVVTVQYRLGVLGFFSTGDEH 192 A S RP +++ HGGA + G+ Y G + LA + V++ + YR D H Sbjct: 106 AASSRPRRGIIFYHGGATVFGSLDCYHGLCNYLARETESVLLMIGYR-------KLPDHH 158 Query: 193 APGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGL 238 +P F D + A + + +G D + V V G S GG+ ++ + Sbjct: 159 SPAL--FQDCMNASIHFLKALETYGVDPSRVVVCGESVGGAAVAAI 202 >gi|23510451 N-acylaminoacyl-peptide hydrolase [Homo sapiens] Length = 732 Score = 33.9 bits (76), Expect = 0.41 Identities = 31/108 (28%), Positives = 43/108 (39%), Gaps = 1/108 (0%) Query: 132 PAEVPAGSGRPVMVWVHGGALITGAATSYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDE 191 P P + P++V HGG + A+ V+ V YR G GF Sbjct: 491 PGSPPDKTQVPMVVMPHGGPHSSFVTAWMLFPAMLCKMGFAVLLVNYR-GSTGFGQDSIL 549 Query: 192 HAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLV 239 PGN G DV V++ + D + V + GGS GG I L+ Sbjct: 550 SLPGNVGHQDVKDVQFAVEQVLQEEHFDASHVALMGGSHGGFISCHLI 597 >gi|194394146 dipeptidylpeptidase 9 [Homo sapiens] Length = 892 Score = 33.5 bits (75), Expect = 0.54 Identities = 42/180 (23%), Positives = 70/180 (38%), Gaps = 22/180 (12%) Query: 71 GPDRFSAPHPAQPWEGVRDASTAPPMCLQDVESMNSSRFVLNGKQQIFSVSEDCLVLNVY 130 GPD + W + +A++ PP D F +++ + +Y Sbjct: 608 GPDDDPLHKQPRFWASMMEAASCPP----DYVPPEIFHFHTRSDVRLYGM--------IY 655 Query: 131 SPAEVPAGSGRPVMVWVHGGALITGAATSYDG------SALAAYGDVVVVTVQYRLGVLG 184 P + G P +++V+GG + S+ G + LA+ G VVV G Sbjct: 656 KPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRG 715 Query: 185 F-FSTGDEHAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAGGSI-ISGLVLSP 242 F ++ G D V L++V E DL+ V + G S GG + + GL+ P Sbjct: 716 LRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFI--DLSRVAIHGWSYGGFLSLMGLIHKP 773 >gi|16933557 dachsous 1 precursor [Homo sapiens] Length = 3298 Score = 32.0 bits (71), Expect = 1.6 Identities = 23/58 (39%), Positives = 28/58 (48%), Gaps = 3/58 (5%) Query: 230 AGGSIISGLVLSPVAAGLFHRAITQSGVITTPGIIDSHPWPLAQKIANTLACSSSSPA 287 +GG I L S A GLFH T +G ITT I+D W A+ +A SPA Sbjct: 2202 SGGQISYSLAASQPARGLFHVDPT-TGTITTTAILDREIW--AETRLVLMATDRGSPA 2256 >gi|222352145 serine/threonine/tyrosine kinase 1 [Homo sapiens] Length = 422 Score = 31.2 bits (69), Expect = 2.7 Identities = 14/48 (29%), Positives = 25/48 (52%) Query: 347 EFSWLIPRGWGLLDTMEQMSREDMLAISTPVLTSLDVPPEMMPTVIDE 394 + SW G + +++ S E+ L +TP L L VP E + V+++ Sbjct: 72 DLSWEAGHGGNVALPLKETSVENFLGATTPALAKLQVPREQLSEVLEQ 119 >gi|84875539 phosphoribosyl pyrophosphate synthetase 2 isoform 1 [Homo sapiens] Length = 321 Score = 31.2 bits (69), Expect = 2.7 Identities = 19/59 (32%), Positives = 29/59 (49%), Gaps = 11/59 (18%) Query: 188 TGDEHAPGNQGFLDVV--------AALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGL 238 T D HA QGF D+ A L+W++ENIA + NC+ V + G ++ + Sbjct: 129 TMDLHASQIQGFFDIPVDNLYAEPAVLQWIRENIAEW---KNCIIVSPDAGGAKRVTSI 184 >gi|4506129 phosphoribosyl pyrophosphate synthetase 2 isoform 2 [Homo sapiens] Length = 318 Score = 31.2 bits (69), Expect = 2.7 Identities = 19/59 (32%), Positives = 29/59 (49%), Gaps = 11/59 (18%) Query: 188 TGDEHAPGNQGFLDVV--------AALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGL 238 T D HA QGF D+ A L+W++ENIA + NC+ V + G ++ + Sbjct: 126 TMDLHASQIQGFFDIPVDNLYAEPAVLQWIRENIAEW---KNCIIVSPDAGGAKRVTSI 181 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.134 0.414 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 23,973,795 Number of Sequences: 37866 Number of extensions: 1177336 Number of successful extensions: 3043 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 24 Number of HSP's successfully gapped in prelim test: 11 Number of HSP's that attempted gapping in prelim test: 2900 Number of HSP's gapped (non-prelim): 43 length of query: 571 length of database: 18,247,518 effective HSP length: 108 effective length of query: 463 effective length of database: 14,157,990 effective search space: 6555149370 effective search space used: 6555149370 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.