Guide to the Human Genome
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Search of human proteins with 33286430

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|33286430 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 8 isoform b [Homo sapiens]
         (332 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|33286430 solute carrier family 7 (cationic amino acid transpo...   677   0.0  
gi|33286428 solute carrier family 7 (cationic amino acid transpo...   677   0.0  
gi|9790235 solute carrier family 7, member 10 [Homo sapiens]          418   e-117
gi|71979932 solute carrier family 7 (cationic amino acid transpo...   322   2e-88
gi|115648063 solute carrier family 7 (cationic amino acid transp...   281   6e-76
gi|115648022 solute carrier family 7 (cationic amino acid transp...   281   6e-76
gi|186910308 solute carrier family 7 member 7 [Homo sapiens]          266   2e-71
gi|186910306 solute carrier family 7 member 7 [Homo sapiens]          266   2e-71
gi|186910304 solute carrier family 7 member 7 [Homo sapiens]          266   2e-71
gi|7657683 solute carrier family 7, (cationic amino acid transpo...   255   4e-68
gi|187423910 solute carrier family 7, member 9 [Homo sapiens]         222   4e-58
gi|7657591 solute carrier family 7, member 9 [Homo sapiens]           222   4e-58
gi|71999149 solute carrier family 7, (cationic amino acid transp...   141   9e-34
gi|109948288 solute carrier family 7, member 2 isoform 1 [Homo s...    58   1e-08
gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo s...    58   1e-08
gi|114326550 solute carrier family 7 (cationic amino acid transp...    52   6e-07
gi|114326544 solute carrier family 7 (cationic amino acid transp...    52   6e-07
gi|4507047 solute carrier family 7 (cationic amino acid transpor...    52   7e-07
gi|123701900 solute carrier family 12 (potassium/chloride transp...    45   7e-05
gi|198041678 solute carrier family 12 (potassium-chloride transp...    45   1e-04
gi|11968148 solute carrier family 12 (potassium-chloride transpo...    45   1e-04
gi|181337167 solute carrier family 7 (cationic amino acid transp...    42   0.001
gi|31881740 solute carrier family 12 (potassium/chloride transpo...    31   1.3  
gi|216548223 synaptic vesicle glycoprotein 2 [Homo sapiens]            30   3.9  
gi|118582255 ATP-binding cassette, sub-family C, member 8 [Homo ...    29   5.1  
gi|30039714 otopetrin 2 [Homo sapiens]                                 29   5.1  
gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens]       29   6.7  
gi|6912538 neurotensin receptor 2 [Homo sapiens]                       29   6.7  
gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens]       29   6.7  
gi|30089916 phosphofurin acidic cluster sorting protein 1 [Homo ...    28   8.7  

>gi|33286430 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 8 isoform b [Homo
           sapiens]
          Length = 332

 Score =  677 bits (1746), Expect = 0.0
 Identities = 332/332 (100%), Positives = 332/332 (100%)

Query: 1   MGIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYK 60
           MGIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYK
Sbjct: 1   MGIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYK 60

Query: 61  NLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVA 120
           NLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVA
Sbjct: 61  NLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVA 120

Query: 121 LSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSD 180
           LSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSD
Sbjct: 121 LSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSD 180

Query: 181 MYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLW 240
           MYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLW
Sbjct: 181 MYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLW 240

Query: 241 SEPVVCGIGLAIMLTGVPVYFLGVYWQHKPKCFSDFIELLTLVSQKMCVVVYPEVERGSG 300
           SEPVVCGIGLAIMLTGVPVYFLGVYWQHKPKCFSDFIELLTLVSQKMCVVVYPEVERGSG
Sbjct: 241 SEPVVCGIGLAIMLTGVPVYFLGVYWQHKPKCFSDFIELLTLVSQKMCVVVYPEVERGSG 300

Query: 301 TEEANEDMEEQQQPMYQPTPTKDKDVAGQPQP 332
           TEEANEDMEEQQQPMYQPTPTKDKDVAGQPQP
Sbjct: 301 TEEANEDMEEQQQPMYQPTPTKDKDVAGQPQP 332


>gi|33286428 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 8 isoform a [Homo
           sapiens]
          Length = 535

 Score =  677 bits (1746), Expect = 0.0
 Identities = 332/332 (100%), Positives = 332/332 (100%)

Query: 1   MGIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYK 60
           MGIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYK
Sbjct: 204 MGIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYK 263

Query: 61  NLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVA 120
           NLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVA
Sbjct: 264 NLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVA 323

Query: 121 LSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSD 180
           LSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSD
Sbjct: 324 LSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSD 383

Query: 181 MYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLW 240
           MYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLW
Sbjct: 384 MYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLW 443

Query: 241 SEPVVCGIGLAIMLTGVPVYFLGVYWQHKPKCFSDFIELLTLVSQKMCVVVYPEVERGSG 300
           SEPVVCGIGLAIMLTGVPVYFLGVYWQHKPKCFSDFIELLTLVSQKMCVVVYPEVERGSG
Sbjct: 444 SEPVVCGIGLAIMLTGVPVYFLGVYWQHKPKCFSDFIELLTLVSQKMCVVVYPEVERGSG 503

Query: 301 TEEANEDMEEQQQPMYQPTPTKDKDVAGQPQP 332
           TEEANEDMEEQQQPMYQPTPTKDKDVAGQPQP
Sbjct: 504 TEEANEDMEEQQQPMYQPTPTKDKDVAGQPQP 535


>gi|9790235 solute carrier family 7, member 10 [Homo sapiens]
          Length = 523

 Score =  418 bits (1075), Expect = e-117
 Identities = 196/294 (66%), Positives = 241/294 (81%)

Query: 1   MGIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYK 60
           +G++QI +G +  L P NAF  +  P +G +ALAFLQGSFA+ GWNFLNYVTEE+VD  K
Sbjct: 204 VGLLQIFQGHFEELRPSNAFAFWMTPSVGHLALAFLQGSFAFSGWNFLNYVTEEMVDARK 263

Query: 61  NLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVA 120
           NLPRAIFISIPLVTFVY F N+AY TAMSPQELL+SNAVAVTFGEKLLG  +W+MP+SVA
Sbjct: 264 NLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVTFGEKLLGYFSWVMPVSVA 323

Query: 121 LSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSD 180
           LSTFGG+NG LFT SRL F+GAREGHLPS+LAMIHV+ CTPIPALL  C +T ++++  D
Sbjct: 324 LSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHVRHCTPIPALLVCCGATAVIMLVGD 383

Query: 181 MYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLW 240
            YTLINYV FINYL YGVT+ G ++LRW++P + RPIK+NLL P+ YL+FWAFLLVFS  
Sbjct: 384 TYTLINYVSFINYLCYGVTILGLLLLRWRRPALHRPIKVNLLIPVAYLVFWAFLLVFSFI 443

Query: 241 SEPVVCGIGLAIMLTGVPVYFLGVYWQHKPKCFSDFIELLTLVSQKMCVVVYPE 294
           SEP+VCG+G+ I+LTGVP++FLGV+W+ KPKC     E +T   Q++C VVYP+
Sbjct: 444 SEPMVCGVGVIIILTGVPIFFLGVFWRSKPKCVHRLTESMTHWGQELCFVVYPQ 497


>gi|71979932 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 5 [Homo sapiens]
          Length = 507

 Score =  322 bits (826), Expect = 2e-88
 Identities = 153/294 (52%), Positives = 211/294 (71%), Gaps = 1/294 (0%)

Query: 1   MGIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYK 60
           +G VQI KG+   L+P  +FE   + D+G + LA   G FAYGGWN+LN+VTEE+++PY+
Sbjct: 214 LGFVQIGKGDVSNLDPNFSFEG-TKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYR 272

Query: 61  NLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVA 120
           NLP AI IS+P+VT VYV  N+AY T +S +++L+S AVAV FG   LGVM+WI+P+ V 
Sbjct: 273 NLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFVG 332

Query: 121 LSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSD 180
           LS FG VNGSLFTSSRLFF G+REGHLPS+L+MIH +  TP+P+L+FTC+ TLL   + D
Sbjct: 333 LSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSKD 392

Query: 181 MYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLW 240
           ++++IN+  F N+L   + + G I LR +KP++ RPIK+NL  P+ ++L   FL+  S W
Sbjct: 393 IFSVINFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVSFW 452

Query: 241 SEPVVCGIGLAIMLTGVPVYFLGVYWQHKPKCFSDFIELLTLVSQKMCVVVYPE 294
             PV CGIG  I+L+G+PVYF GV+W++KPK     I   T++ QK+  VV  E
Sbjct: 453 KTPVECGIGFTIILSGLPVYFFGVWWKNKPKWLLQGIFSTTVLCQKLMQVVPQE 506


>gi|115648063 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 6 [Homo sapiens]
          Length = 515

 Score =  281 bits (719), Expect = 6e-76
 Identities = 136/300 (45%), Positives = 209/300 (69%), Gaps = 9/300 (3%)

Query: 1   MGIVQICKG--EYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDP 58
           MG+V++C+G  E+F    ++AFE     D+G ++LA     F+Y GW+ LN+VTEE+ +P
Sbjct: 209 MGLVKLCQGHSEHF----QDAFEG-SSWDMGNLSLALYSALFSYSGWDTLNFVTEEIKNP 263

Query: 59  YKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPIS 118
            +NLP AI IS+P+VT +Y+  NVAY T ++  ++L+S+AVAVTF ++  G+ +W +PI+
Sbjct: 264 ERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGMFSWTIPIA 323

Query: 119 VALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVT 178
           VALS FGG+N S+F SSRLFF G+REGHLP +L+MIH++R TPIPALLF C   L+ L+ 
Sbjct: 324 VALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCTMALIYLIV 383

Query: 179 SDMYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFS 238
            D++ LINY  F  + F G++V GQ+ LRWK+P  PRP+K+++ FPI++ +   FL++  
Sbjct: 384 EDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCICSVFLVIVP 443

Query: 239 LWSEPVVCGIGLAIMLTGVPVYFLGVYW--QHKPKCFSDFIELLTLVSQKMCVVVYPEVE 296
           L+++ +   IG+ I L+GVP YF+GVY     +P    + +  +T  +Q++C  V  E++
Sbjct: 444 LFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFIRNVLAAITRGTQQLCFCVLTELD 503


>gi|115648022 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 6 [Homo sapiens]
          Length = 515

 Score =  281 bits (719), Expect = 6e-76
 Identities = 136/300 (45%), Positives = 209/300 (69%), Gaps = 9/300 (3%)

Query: 1   MGIVQICKG--EYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDP 58
           MG+V++C+G  E+F    ++AFE     D+G ++LA     F+Y GW+ LN+VTEE+ +P
Sbjct: 209 MGLVKLCQGHSEHF----QDAFEG-SSWDMGNLSLALYSALFSYSGWDTLNFVTEEIKNP 263

Query: 59  YKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPIS 118
            +NLP AI IS+P+VT +Y+  NVAY T ++  ++L+S+AVAVTF ++  G+ +W +PI+
Sbjct: 264 ERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGMFSWTIPIA 323

Query: 119 VALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVT 178
           VALS FGG+N S+F SSRLFF G+REGHLP +L+MIH++R TPIPALLF C   L+ L+ 
Sbjct: 324 VALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCTMALIYLIV 383

Query: 179 SDMYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFS 238
            D++ LINY  F  + F G++V GQ+ LRWK+P  PRP+K+++ FPI++ +   FL++  
Sbjct: 384 EDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCICSVFLVIVP 443

Query: 239 LWSEPVVCGIGLAIMLTGVPVYFLGVYW--QHKPKCFSDFIELLTLVSQKMCVVVYPEVE 296
           L+++ +   IG+ I L+GVP YF+GVY     +P    + +  +T  +Q++C  V  E++
Sbjct: 444 LFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFIRNVLAAITRGTQQLCFCVLTELD 503


>gi|186910308 solute carrier family 7 member 7 [Homo sapiens]
          Length = 511

 Score =  266 bits (679), Expect = 2e-71
 Identities = 139/315 (44%), Positives = 205/315 (65%), Gaps = 10/315 (3%)

Query: 2   GIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKN 61
           GIV++ +G     E  N+FE      +G +ALA     F+Y GW+ LNYVTEE+ +P +N
Sbjct: 202 GIVRLGQGASTHFE--NSFEGSSFA-VGDIALALYSALFSYSGWDTLNYVTEEIKNPERN 258

Query: 62  LPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVAL 121
           LP +I IS+P+VT +Y+  NVAY T +  +++LAS+AVAVTF +++ G+  WI+P+SVAL
Sbjct: 259 LPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGIFNWIIPLSVAL 318

Query: 122 STFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDM 181
           S FGG+N S+  +SRLFF G+REGHLP  + MIHV+R TP+P+LLF  I  L+ L   D+
Sbjct: 319 SCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGIMALIYLCVEDI 378

Query: 182 YTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLWS 241
           + LINY  F  + F G+++ GQ+ LRWK+PD PRP+K+++ FPI++ L   FL+   L+S
Sbjct: 379 FQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCLCTIFLVAVPLYS 438

Query: 242 EPVVCGIGLAIMLTGVPVYFLGV-YWQHK-PKCFSDFIELLTLVSQKMCVVVYPEVERGS 299
           + +   IG+AI L+G+P YFL +   +HK P      +   T   Q +C+ V  E++   
Sbjct: 439 DTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVLCMSVAAEMDLED 498

Query: 300 GTEEANEDMEEQQQP 314
           G E     M +Q+ P
Sbjct: 499 GGE-----MPKQRDP 508


>gi|186910306 solute carrier family 7 member 7 [Homo sapiens]
          Length = 511

 Score =  266 bits (679), Expect = 2e-71
 Identities = 139/315 (44%), Positives = 205/315 (65%), Gaps = 10/315 (3%)

Query: 2   GIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKN 61
           GIV++ +G     E  N+FE      +G +ALA     F+Y GW+ LNYVTEE+ +P +N
Sbjct: 202 GIVRLGQGASTHFE--NSFEGSSFA-VGDIALALYSALFSYSGWDTLNYVTEEIKNPERN 258

Query: 62  LPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVAL 121
           LP +I IS+P+VT +Y+  NVAY T +  +++LAS+AVAVTF +++ G+  WI+P+SVAL
Sbjct: 259 LPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGIFNWIIPLSVAL 318

Query: 122 STFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDM 181
           S FGG+N S+  +SRLFF G+REGHLP  + MIHV+R TP+P+LLF  I  L+ L   D+
Sbjct: 319 SCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGIMALIYLCVEDI 378

Query: 182 YTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLWS 241
           + LINY  F  + F G+++ GQ+ LRWK+PD PRP+K+++ FPI++ L   FL+   L+S
Sbjct: 379 FQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCLCTIFLVAVPLYS 438

Query: 242 EPVVCGIGLAIMLTGVPVYFLGV-YWQHK-PKCFSDFIELLTLVSQKMCVVVYPEVERGS 299
           + +   IG+AI L+G+P YFL +   +HK P      +   T   Q +C+ V  E++   
Sbjct: 439 DTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVLCMSVAAEMDLED 498

Query: 300 GTEEANEDMEEQQQP 314
           G E     M +Q+ P
Sbjct: 499 GGE-----MPKQRDP 508


>gi|186910304 solute carrier family 7 member 7 [Homo sapiens]
          Length = 511

 Score =  266 bits (679), Expect = 2e-71
 Identities = 139/315 (44%), Positives = 205/315 (65%), Gaps = 10/315 (3%)

Query: 2   GIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKN 61
           GIV++ +G     E  N+FE      +G +ALA     F+Y GW+ LNYVTEE+ +P +N
Sbjct: 202 GIVRLGQGASTHFE--NSFEGSSFA-VGDIALALYSALFSYSGWDTLNYVTEEIKNPERN 258

Query: 62  LPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVAL 121
           LP +I IS+P+VT +Y+  NVAY T +  +++LAS+AVAVTF +++ G+  WI+P+SVAL
Sbjct: 259 LPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGIFNWIIPLSVAL 318

Query: 122 STFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDM 181
           S FGG+N S+  +SRLFF G+REGHLP  + MIHV+R TP+P+LLF  I  L+ L   D+
Sbjct: 319 SCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGIMALIYLCVEDI 378

Query: 182 YTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLWS 241
           + LINY  F  + F G+++ GQ+ LRWK+PD PRP+K+++ FPI++ L   FL+   L+S
Sbjct: 379 FQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCLCTIFLVAVPLYS 438

Query: 242 EPVVCGIGLAIMLTGVPVYFLGV-YWQHK-PKCFSDFIELLTLVSQKMCVVVYPEVERGS 299
           + +   IG+AI L+G+P YFL +   +HK P      +   T   Q +C+ V  E++   
Sbjct: 439 DTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVLCMSVAAEMDLED 498

Query: 300 GTEEANEDMEEQQQP 314
           G E     M +Q+ P
Sbjct: 499 GGE-----MPKQRDP 508


>gi|7657683 solute carrier family 7, (cationic amino acid
           transporter, y+ system) member 11 [Homo sapiens]
          Length = 501

 Score =  255 bits (651), Expect = 4e-68
 Identities = 134/296 (45%), Positives = 193/296 (65%), Gaps = 4/296 (1%)

Query: 2   GIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKN 61
           G++Q+ KG+      K+AF   ++  I  + LAF  G +AY GW +LN+VTEE+ +P K 
Sbjct: 209 GVMQLIKGQT--QNFKDAFSG-RDSSITRLPLAFYYGMYAYAGWFYLNFVTEEVENPEKT 265

Query: 62  LPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVAL 121
           +P AI IS+ +VT  YV  NVAY T ++ +ELL SNAVAVTF E+LLG  +  +PI VAL
Sbjct: 266 IPLAICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERLLGNFSLAVPIFVAL 325

Query: 122 STFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDM 181
           S FG +NG +F  SRLF+  +REGHLP +L+MIHV++ TP+PA++     T++ML + D+
Sbjct: 326 SCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHVRKHTPLPAVIVLHPLTMIMLFSGDL 385

Query: 182 YTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLWS 241
            +L+N++ F  +LF G+ VAG I LR+K PD+ RP K+ L  P ++     F++  SL+S
Sbjct: 386 DSLLNFLSFARWLFIGLAVAGLIYLRYKCPDMHRPFKVPLFIPALFSFTCLFMVALSLYS 445

Query: 242 EPVVCGIGLAIMLTGVPVYFLGVYWQHKPKCFSDFIELLTLVSQKMCVVVYPEVER 297
           +P   GIG  I LTGVP Y+L + W  KP+ F    E +T   Q +  VV PE ++
Sbjct: 446 DPFSTGIGFVITLTGVPAYYLFIIWDKKPRWFRIMSEKITRTLQIILEVV-PEEDK 500


>gi|187423910 solute carrier family 7, member 9 [Homo sapiens]
          Length = 487

 Score =  222 bits (565), Expect = 4e-58
 Identities = 112/254 (44%), Positives = 168/254 (66%), Gaps = 8/254 (3%)

Query: 18  NAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVY 77
           N+FE  Q   +G ++LAF  G +AY GWN LNY+TEEL +PY+NLP AI I IPLVT  Y
Sbjct: 209 NSFEGAQL-SVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAIIIGIPLVTACY 267

Query: 78  VFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVALSTFGGVNGSLFTSSRL 137
           +  NV+Y T M+  ELL S AVAVTFG+++L   +WI+P+ VA ST G  NG+ FT+ RL
Sbjct: 268 ILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAANGTCFTAGRL 327

Query: 138 FFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDMYTLINYVGFINYLFYG 197
            +   REGH+  VL+ I V+R TP PA++F  I   + ++  D+ +L+NY  F  +LFYG
Sbjct: 328 IYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNYFSFAAWLFYG 387

Query: 198 VTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLWSEP----VVCGIGLAIM 253
           +T+ G IV+R+ + ++ RPIK+ ++ P++  L   FL++  + S+P    + C   +  +
Sbjct: 388 LTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEYLYC---VLFI 444

Query: 254 LTGVPVYFLGVYWQ 267
           L+G+  YFL V+++
Sbjct: 445 LSGLLFYFLFVHYK 458


>gi|7657591 solute carrier family 7, member 9 [Homo sapiens]
          Length = 487

 Score =  222 bits (565), Expect = 4e-58
 Identities = 112/254 (44%), Positives = 168/254 (66%), Gaps = 8/254 (3%)

Query: 18  NAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVY 77
           N+FE  Q   +G ++LAF  G +AY GWN LNY+TEEL +PY+NLP AI I IPLVT  Y
Sbjct: 209 NSFEGAQL-SVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAIIIGIPLVTACY 267

Query: 78  VFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVALSTFGGVNGSLFTSSRL 137
           +  NV+Y T M+  ELL S AVAVTFG+++L   +WI+P+ VA ST G  NG+ FT+ RL
Sbjct: 268 ILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAANGTCFTAGRL 327

Query: 138 FFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDMYTLINYVGFINYLFYG 197
            +   REGH+  VL+ I V+R TP PA++F  I   + ++  D+ +L+NY  F  +LFYG
Sbjct: 328 IYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNYFSFAAWLFYG 387

Query: 198 VTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLWSEP----VVCGIGLAIM 253
           +T+ G IV+R+ + ++ RPIK+ ++ P++  L   FL++  + S+P    + C   +  +
Sbjct: 388 LTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEYLYC---VLFI 444

Query: 254 LTGVPVYFLGVYWQ 267
           L+G+  YFL V+++
Sbjct: 445 LSGLLFYFLFVHYK 458


>gi|71999149 solute carrier family 7, (cationic amino acid
           transporter, y+ system) member 13 [Homo sapiens]
          Length = 470

 Score =  141 bits (355), Expect = 9e-34
 Identities = 86/280 (30%), Positives = 155/280 (55%), Gaps = 10/280 (3%)

Query: 2   GIVQICKGEYFWLEP-KNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYK 60
           G+V + +G+   +E  +NAF+  + PDI  +  A  QG FAY G      +  EL  P  
Sbjct: 178 GVVFLIRGKKENVERFQNAFDA-ELPDISHLIQAIFQGYFAYSGGACFTLIAGELKKPRT 236

Query: 61  NLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVA 120
            +P+ IF ++PLVT VY+  N++Y+T ++P+E+L+S+AVA+T+ ++    +AWIMP +++
Sbjct: 237 TIPKCIFTALPLVTVVYLLVNISYLTVLTPREILSSDAVAITWADRAFPSLAWIMPFAIS 296

Query: 121 LSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSD 180
            S F  +  S+F SSR  +  ++EG LP +   ++    +P  A+L       L ++ + 
Sbjct: 297 TSLFSNLLISIFKSSRPIYLASQEGQLPLLFNTLN-SHSSPFTAVLLLVTLGSLAIILTS 355

Query: 181 MYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLW 240
           +  LINY+ F   L+  + + G +  R+++P++  P K+ L FP+  ++    L+V  L 
Sbjct: 356 LIDLINYIFFTGSLWSILLMIGILRRRYQEPNLSIPYKVFLSFPLATIVIDVGLVVIPLV 415

Query: 241 SEPVVCGI-GLAIMLTGVPVYF------LGVYWQHKPKCF 273
             P V  +  L ++L+G+  Y       + + W  K  C+
Sbjct: 416 KSPNVHYVYVLLLVLSGLLFYIPLIHFKIRLAWFEKMTCY 455


>gi|109948288 solute carrier family 7, member 2 isoform 1 [Homo
           sapiens]
          Length = 697

 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 47/171 (27%), Positives = 83/171 (48%), Gaps = 3/171 (1%)

Query: 40  FAYGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNA- 98
           +A+ G++ +    EE+ +P K +P  I  S+ LV F+  F   A +T M P  LL   + 
Sbjct: 306 YAFVGFDCIATTGEEVRNPQKAIPIGIVTSL-LVCFMAYFGVSAALTLMMPYYLLDEKSP 364

Query: 99  VAVTFGEKLLGVMAWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKR 158
           + V F     G   +++      +    + GS+F   R+ FA AR+G L   LA +  KR
Sbjct: 365 LPVAFEYVGWGPAKYVVAAGSLCALSTSLLGSMFPLPRILFAMARDGLLFRFLARVS-KR 423

Query: 159 CTPIPALLFTCISTLLMLVTSDMYTLINYVGFINYLFYGVTVAGQIVLRWK 209
            +P+ A L   + + LM    D+  L++ +     + Y +  A  ++LR++
Sbjct: 424 QSPVAATLTAGVISALMAFLFDLKALVDMMSIGTLMAYSLVAACVLILRYQ 474


>gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo
           sapiens]
          Length = 658

 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 47/171 (27%), Positives = 81/171 (47%), Gaps = 2/171 (1%)

Query: 40  FAYGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNA- 98
           +A+ G++ +    EE+ +P K +P  I  S+ LV F+  F   A +T M P  LL   + 
Sbjct: 266 YAFVGFDCIATTGEEVRNPQKAIPIGIVTSL-LVCFMAYFGVSAALTLMMPYYLLDEKSP 324

Query: 99  VAVTFGEKLLGVMAWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKR 158
           + V F     G   +++      +    + GS+F   R+ +A A +G L   LA I+ K 
Sbjct: 325 LPVAFEYVGWGPAKYVVAAGSLCALSTSLLGSIFPMPRVIYAMAEDGLLFKCLAQINSKT 384

Query: 159 CTPIPALLFTCISTLLMLVTSDMYTLINYVGFINYLFYGVTVAGQIVLRWK 209
            TPI A L +     LM    D+  L++ +     + Y +  A  ++LR++
Sbjct: 385 KTPIIATLSSGAVAALMAFLFDLKALVDMMSIGTLMAYSLVAACVLILRYQ 435


>gi|114326550 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 3 [Homo sapiens]
          Length = 619

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 54/269 (20%), Positives = 107/269 (39%), Gaps = 42/269 (15%)

Query: 40  FAYGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAV 99
           +A+ G++ +    EE  +P +++P  I IS+ +    Y   + A    M   +L   + +
Sbjct: 262 YAFVGFDCIATTGEEAQNPQRSIPMGIVISLSVCFLAYFAVSSALTLMMPYYQLQPESPL 321

Query: 100 AVTFGEKLLGVMAWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRC 159
              F         +++ +    +    + GS+F   R+ +A A +G L  VLA IH    
Sbjct: 322 PEAFLYIGWAPARYVVAVGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRVLARIHTGTR 381

Query: 160 TPIPALLFTCISTLLMLVTSDMYTLINYVGFINYLFYGVTVAGQIVLRWKKPD------- 212
           TPI A + + I    M     +  L++ +     L Y +     ++LR+ +PD       
Sbjct: 382 TPIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSICVLILRY-QPDQETKTGE 440

Query: 213 ---------------------------IPRPIKINLLF---PIIYLLFWAFLLVFSLWSE 242
                                      IP P+   +++    ++ +L  A  LV + WS 
Sbjct: 441 EVELQEEAITTESEKLTLWGLFFPLNSIPTPLSGQIVYVCSSLLAVLLTALCLVLAQWSV 500

Query: 243 PVVCG----IGLAIMLTGVPVYFLGVYWQ 267
           P++ G      + ++L  + +  + V W+
Sbjct: 501 PLLSGDLLWTAVVVLLLLLIIGIIVVIWR 529


>gi|114326544 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 3 [Homo sapiens]
          Length = 619

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 54/269 (20%), Positives = 107/269 (39%), Gaps = 42/269 (15%)

Query: 40  FAYGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAV 99
           +A+ G++ +    EE  +P +++P  I IS+ +    Y   + A    M   +L   + +
Sbjct: 262 YAFVGFDCIATTGEEAQNPQRSIPMGIVISLSVCFLAYFAVSSALTLMMPYYQLQPESPL 321

Query: 100 AVTFGEKLLGVMAWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRC 159
              F         +++ +    +    + GS+F   R+ +A A +G L  VLA IH    
Sbjct: 322 PEAFLYIGWAPARYVVAVGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRVLARIHTGTR 381

Query: 160 TPIPALLFTCISTLLMLVTSDMYTLINYVGFINYLFYGVTVAGQIVLRWKKPD------- 212
           TPI A + + I    M     +  L++ +     L Y +     ++LR+ +PD       
Sbjct: 382 TPIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSICVLILRY-QPDQETKTGE 440

Query: 213 ---------------------------IPRPIKINLLF---PIIYLLFWAFLLVFSLWSE 242
                                      IP P+   +++    ++ +L  A  LV + WS 
Sbjct: 441 EVELQEEAITTESEKLTLWGLFFPLNSIPTPLSGQIVYVCSSLLAVLLTALCLVLAQWSV 500

Query: 243 PVVCG----IGLAIMLTGVPVYFLGVYWQ 267
           P++ G      + ++L  + +  + V W+
Sbjct: 501 PLLSGDLLWTAVVVLLLLLIIGIIVVIWR 529


>gi|4507047 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 1 [Homo sapiens]
          Length = 629

 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 45/176 (25%), Positives = 83/176 (47%), Gaps = 3/176 (1%)

Query: 40  FAYGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNA- 98
           +A+ G++ +    EE+ +P K +P  I  S+ L+ F+  F   A +T M P   L +N+ 
Sbjct: 264 YAFVGFDCIATTGEEVKNPQKAIPVGIVASL-LICFIAYFGVSAALTLMMPYFCLDNNSP 322

Query: 99  VAVTFGEKLLGVMAWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKR 158
           +   F         + + +    +    + GS+F   R+ +A A +G L   LA ++ + 
Sbjct: 323 LPDAFKHVGWEGAKYAVAVGSLCALSASLLGSMFPMPRVIYAMAEDGLLFKFLANVNDRT 382

Query: 159 CTPIPALLFTCISTLLMLVTSDMYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIP 214
            TPI A L +     +M    D+  L++ +     L Y +  A  +VLR+ +P+ P
Sbjct: 383 KTPIIATLASGAVAAVMAFLFDLKDLVDLMSIGTLLAYSLVAACVLVLRY-QPEQP 437


>gi|123701900 solute carrier family 12 (potassium/chloride
           transporters), member 7 [Homo sapiens]
          Length = 1083

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 44/162 (27%), Positives = 73/162 (45%), Gaps = 9/162 (5%)

Query: 54  ELVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAW 113
           +L D  K++P    ++I   +F+Y+   V +   +    L      A+  G  ++G++AW
Sbjct: 443 DLKDAQKSIPTGTILAIVTTSFIYLSCIVLFGACIEGVVLRDKFGEALQ-GNLVIGMLAW 501

Query: 114 IMP----ISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVK-RCTPIPALLFT 168
             P    I    ST G    SL  + RL  A AR+G +P +    H K    P  ALL T
Sbjct: 502 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIARDGIVPFLQVFGHGKANGEPTWALLLT 561

Query: 169 ---CISTLLMLVTSDMYTLINYVGFINYLFYGVTVAGQIVLR 207
              C + +L+     +  +++    + YLF  +  A Q +LR
Sbjct: 562 VLICETGILIASLDSVAPILSMFFLMCYLFVNLACAVQTLLR 603


>gi|198041678 solute carrier family 12 (potassium-chloride
           transporter), member 5 isoform 1 [Homo sapiens]
          Length = 1139

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 53/206 (25%), Positives = 92/206 (44%), Gaps = 25/206 (12%)

Query: 54  ELVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAW 113
           +L D  K++P    ++I   + VY+ + V +   +    L      AV  G  ++G +AW
Sbjct: 446 DLRDAQKSIPTGTILAIATTSAVYISSVVLFGACIEGVVLRDKFGEAVN-GNLVVGTLAW 504

Query: 114 IMP----ISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVK-RCTPIPALLFT 168
             P    I    ST G    SL  + RL  A +R+G +P +    H K    P  ALL T
Sbjct: 505 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKANGEPTWALLLT 564

Query: 169 -CISTLLMLVTS--DMYTLINYVGFINYLFYGVTVAGQIVLR---WKKPDIPR------- 215
            CI  + +L+ S  ++  +++    + Y+F  +  A Q +LR   W+    PR       
Sbjct: 565 ACICEIGILIASLDEVAPILSMFFLMCYMFVNLACAVQTLLRTPNWR----PRFRYYHWT 620

Query: 216 --PIKINLLFPIIYLLFWAFLLVFSL 239
              + ++L   ++++  W + LV  L
Sbjct: 621 LSFLGMSLCLALMFICSWYYALVAML 646


>gi|11968148 solute carrier family 12 (potassium-chloride
           transporter), member 5 isoform 2 [Homo sapiens]
          Length = 1116

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 53/206 (25%), Positives = 92/206 (44%), Gaps = 25/206 (12%)

Query: 54  ELVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAW 113
           +L D  K++P    ++I   + VY+ + V +   +    L      AV  G  ++G +AW
Sbjct: 423 DLRDAQKSIPTGTILAIATTSAVYISSVVLFGACIEGVVLRDKFGEAVN-GNLVVGTLAW 481

Query: 114 IMP----ISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVK-RCTPIPALLFT 168
             P    I    ST G    SL  + RL  A +R+G +P +    H K    P  ALL T
Sbjct: 482 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKANGEPTWALLLT 541

Query: 169 -CISTLLMLVTS--DMYTLINYVGFINYLFYGVTVAGQIVLR---WKKPDIPR------- 215
            CI  + +L+ S  ++  +++    + Y+F  +  A Q +LR   W+    PR       
Sbjct: 542 ACICEIGILIASLDEVAPILSMFFLMCYMFVNLACAVQTLLRTPNWR----PRFRYYHWT 597

Query: 216 --PIKINLLFPIIYLLFWAFLLVFSL 239
              + ++L   ++++  W + LV  L
Sbjct: 598 LSFLGMSLCLALMFICSWYYALVAML 623


>gi|181337167 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 14 [Homo sapiens]
          Length = 771

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 43/182 (23%), Positives = 81/182 (44%), Gaps = 12/182 (6%)

Query: 36  LQGS----FAYGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQ 91
           LQG+    +A+ G++ +    EE  +P  ++P AI  S+ +    YV  +V  +T M P 
Sbjct: 255 LQGAATCFYAFIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSVI-LTLMVPY 313

Query: 92  ELLASNAVAVTFGEKLLGVMAWIMPISVALSTFGGVN----GSLFTSSRLFFAGAREGHL 147
             + + +  +   E  +    +     VA+ +  G+     GSLF   R+ +A A +G L
Sbjct: 314 YTIDTESPLM---EMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLL 370

Query: 148 PSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDMYTLINYVGFINYLFYGVTVAGQIVLR 207
              LA +     TP+ A + +     L+ +   +  LI  +     L Y +     ++LR
Sbjct: 371 FRFLAHVSSYTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLR 430

Query: 208 WK 209
           ++
Sbjct: 431 YQ 432


>gi|31881740 solute carrier family 12 (potassium/chloride
           transporters), member 9 [Homo sapiens]
          Length = 914

 Score = 31.2 bits (69), Expect = 1.3
 Identities = 38/171 (22%), Positives = 70/171 (40%), Gaps = 19/171 (11%)

Query: 54  ELVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLAS------NAVAVTFGEKL 107
           EL DP + +P    +++    FVYV   + ++++ +    L         A+++     L
Sbjct: 290 ELKDPSRAIPLGTIVAVAYTFFVYVL--LFFLSSFTCDRTLLQEDYGFFRAISLWPPLVL 347

Query: 108 LGVMAWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHV--KRCTPIPAL 165
           +G+ A  +  S++         SL  +SR+  A AR+     +LA   V  +   P  A+
Sbjct: 348 IGIYATALSASMS---------SLIGASRILHALARDDLFGVILAPAKVVSRGGNPWAAV 398

Query: 166 LFTCISTLLMLVTSDMYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRP 216
           L++     L+L+   + TL   V     + Y       + L W      RP
Sbjct: 399 LYSWGLVQLVLLAGKLNTLAAVVTVFYLVAYAAVDLSCLSLEWASAPNFRP 449


>gi|216548223 synaptic vesicle glycoprotein 2 [Homo sapiens]
          Length = 742

 Score = 29.6 bits (65), Expect = 3.9
 Identities = 23/86 (26%), Positives = 40/86 (46%), Gaps = 5/86 (5%)

Query: 20  FENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKNLPRAIFIS----IPLVTF 75
           F +F   +  ++AL  L G  +   WN L+ +T EL    K      F++    +  V  
Sbjct: 641 FLSFGNSESAMIALLCLFGGVSIASWNALDVLTVELYPSDKRTTAFGFLNALCKLAAVLG 700

Query: 76  VYVFANVAYVTAMSPQELLASNAVAV 101
           + +F +   +T  +P  L AS A+A+
Sbjct: 701 ISIFTSFVGITKAAP-ILFASAALAL 725


>gi|118582255 ATP-binding cassette, sub-family C, member 8 [Homo
           sapiens]
          Length = 1581

 Score = 29.3 bits (64), Expect = 5.1
 Identities = 38/139 (27%), Positives = 58/139 (41%), Gaps = 25/139 (17%)

Query: 129 GSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLML---VTSDMYTLI 185
           G  F SS+ F A A    L  +L +  + + T + A  +  I T + L   + + +Y  I
Sbjct: 342 GVYFVSSQEFLANAYV--LAVLLFLALLLQRTFLQASYYVAIETGINLRGAIQTKIYNKI 399

Query: 186 NYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLWSEPVV 245
            ++   N L  G   AGQI               NL+      L W F L  +LW+ PV 
Sbjct: 400 MHLSTSN-LSMGEMTAGQIC--------------NLVAIDTNQLMWFFFLCPNLWAMPVQ 444

Query: 246 CGIGLAIMLTGVPVYFLGV 264
             +G+ ++      Y LGV
Sbjct: 445 IIVGVILL-----YYILGV 458


>gi|30039714 otopetrin 2 [Homo sapiens]
          Length = 562

 Score = 29.3 bits (64), Expect = 5.1
 Identities = 19/68 (27%), Positives = 31/68 (45%), Gaps = 3/68 (4%)

Query: 28  IGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANVAYVTA 87
           +GL  L  L GS  Y    F     +   +P + L  A+ +   L  +   + ++  V A
Sbjct: 336 LGLTTLVSLSGSIIY---RFDRRAMDHHKNPTRTLDVALLMGAALGQYAISYYSIVAVVA 392

Query: 88  MSPQELLA 95
            +PQ+LLA
Sbjct: 393 GTPQDLLA 400


>gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens]
          Length = 1191

 Score = 28.9 bits (63), Expect = 6.7
 Identities = 15/73 (20%), Positives = 31/73 (42%), Gaps = 3/73 (4%)

Query: 7  CKGEYFWLEPKNAFENFQEPDIGLVAL---AFLQGSFAYGGWNFLNYVTEELVDPYKNLP 63
          C GE  W++ +  +   +EP  G  A     +         + F N++ + L + ++ + 
Sbjct: 14 CAGEENWVDSRTIYVGHREPPPGAEAYIPQRYPDNRIVSSKYTFWNFIPKNLFEQFRRVA 73

Query: 64 RAIFISIPLVTFV 76
             F+ I LV  +
Sbjct: 74 NFYFLIIFLVQLI 86


>gi|6912538 neurotensin receptor 2 [Homo sapiens]
          Length = 410

 Score = 28.9 bits (63), Expect = 6.7
 Identities = 21/73 (28%), Positives = 26/73 (35%), Gaps = 18/73 (24%)

Query: 221 LLFPIIYLLFWAFLLVFSLWSEPVVCGI------------------GLAIMLTGVPVYFL 262
           +LF  +Y L WA     +  S  VV                     GL ++L GVPV   
Sbjct: 33  VLFTALYALIWALGAAGNALSVHVVLKARAGRAGRLRHHVLSLALAGLLLLLVGVPVELY 92

Query: 263 GVYWQHKPKCFSD 275
              W H P  F D
Sbjct: 93  SFVWFHYPWVFGD 105


>gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens]
          Length = 1134

 Score = 28.9 bits (63), Expect = 6.7
 Identities = 15/73 (20%), Positives = 31/73 (42%), Gaps = 3/73 (4%)

Query: 7  CKGEYFWLEPKNAFENFQEPDIGLVAL---AFLQGSFAYGGWNFLNYVTEELVDPYKNLP 63
          C GE  W++ +  +   +EP  G  A     +         + F N++ + L + ++ + 
Sbjct: 14 CAGEENWVDSRTIYVGHREPPPGAEAYIPQRYPDNRIVSSKYTFWNFIPKNLFEQFRRVA 73

Query: 64 RAIFISIPLVTFV 76
             F+ I LV  +
Sbjct: 74 NFYFLIIFLVQLI 86


>gi|30089916 phosphofurin acidic cluster sorting protein 1 [Homo
           sapiens]
          Length = 963

 Score = 28.5 bits (62), Expect = 8.7
 Identities = 13/30 (43%), Positives = 19/30 (63%), Gaps = 3/30 (10%)

Query: 296 ERGSGTEEANED---MEEQQQPMYQPTPTK 322
           +RGSG  ++ +     ++QQQP  QPTP K
Sbjct: 20  QRGSGVAQSPQQPPPQQQQQQPPQQPTPPK 49


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.142    0.446 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,909,733
Number of Sequences: 37866
Number of extensions: 565291
Number of successful extensions: 2048
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 2010
Number of HSP's gapped (non-prelim): 41
length of query: 332
length of database: 18,247,518
effective HSP length: 103
effective length of query: 229
effective length of database: 14,347,320
effective search space: 3285536280
effective search space used: 3285536280
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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