BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|32996709 transmembrane emp24 protein transport domain containing 7 [Homo sapiens] (224 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|32996709 transmembrane emp24 protein transport domain contain... 459 e-130 gi|6679189 transmembrane emp24 domain containing 3 [Homo sapiens] 287 6e-78 gi|5803149 coated vesicle membrane protein [Homo sapiens] 123 1e-28 gi|5803040 interleukin 1 receptor-like 1 ligand precursor [Homo ... 106 1e-23 gi|19923442 transmembrane emp24 protein transport domain contain... 104 7e-23 gi|33457308 transmembrane emp24 protein transport domain contain... 83 2e-16 gi|39725636 transmembrane emp24 protein transport domain contain... 79 4e-15 gi|98986464 transmembrane emp24 domain-containing protein 10 pre... 73 2e-13 gi|21389573 transmembrane emp24 protein transport domain contain... 47 1e-05 gi|53729352 WD repeat-containing protein 1 isoform 2 [Homo sapiens] 30 1.3 gi|9257257 WD repeat-containing protein 1 isoform 1 [Homo sapiens] 30 1.3 gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo sapi... 29 2.8 gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens] 29 2.8 gi|4885631 tyrosine kinase with immunoglobulin-like and EGF-like... 28 4.9 gi|239748723 PREDICTED: hypothetical protein XP_002346783 [Homo ... 28 8.3 gi|239743851 PREDICTED: hypothetical protein [Homo sapiens] 28 8.3 gi|239743848 PREDICTED: hypothetical protein [Homo sapiens] 28 8.3 gi|239743746 PREDICTED: hypothetical protein [Homo sapiens] 28 8.3 >gi|32996709 transmembrane emp24 protein transport domain containing 7 [Homo sapiens] Length = 224 Score = 459 bits (1181), Expect = e-130 Identities = 224/224 (100%), Positives = 224/224 (100%) Query: 1 MPRPGSAQRWAAVAGRWGCRLLALLLLVPGPGGASEITFELPDNAKQCFYEDIAQGTKCT 60 MPRPGSAQRWAAVAGRWGCRLLALLLLVPGPGGASEITFELPDNAKQCFYEDIAQGTKCT Sbjct: 1 MPRPGSAQRWAAVAGRWGCRLLALLLLVPGPGGASEITFELPDNAKQCFYEDIAQGTKCT 60 Query: 61 LEFQVITGGHYDVDCRLEDPDGKVLYKEMKKQYDSFTFTASKNGTYKFCFSNEFSTFTHK 120 LEFQVITGGHYDVDCRLEDPDGKVLYKEMKKQYDSFTFTASKNGTYKFCFSNEFSTFTHK Sbjct: 61 LEFQVITGGHYDVDCRLEDPDGKVLYKEMKKQYDSFTFTASKNGTYKFCFSNEFSTFTHK 120 Query: 121 TVYFDFQVGEDPPLFPSENRVSALTQMESACVSIHEALKSVIDYQTHFRLREAQGRSRAE 180 TVYFDFQVGEDPPLFPSENRVSALTQMESACVSIHEALKSVIDYQTHFRLREAQGRSRAE Sbjct: 121 TVYFDFQVGEDPPLFPSENRVSALTQMESACVSIHEALKSVIDYQTHFRLREAQGRSRAE 180 Query: 181 DLNTRVAYWSVGEALILLVVSIGQVFLLKSFFSDKRTTTTRVGS 224 DLNTRVAYWSVGEALILLVVSIGQVFLLKSFFSDKRTTTTRVGS Sbjct: 181 DLNTRVAYWSVGEALILLVVSIGQVFLLKSFFSDKRTTTTRVGS 224 >gi|6679189 transmembrane emp24 domain containing 3 [Homo sapiens] Length = 217 Score = 287 bits (734), Expect = 6e-78 Identities = 140/205 (68%), Positives = 167/205 (81%), Gaps = 2/205 (0%) Query: 21 LLALLLLVPGPGGASEITFELPDNAKQCFYEDIAQGTKCTLEFQVITGGHYDVDCRLEDP 80 LL LL P GA E+TFELPDNAKQCF+E++ QG K +L++QVITGGHYDVDC +EDP Sbjct: 14 LLLLLRRAEQPCGA-ELTFELPDNAKQCFHEEVEQGVKFSLDYQVITGGHYDVDCYVEDP 72 Query: 81 DGKVLYKEMKKQYDSFTFTASKNGTYKFCFSNEFSTFTHKTVYFDFQVGEDPPLFPS-EN 139 G +Y+E KKQYDSFT+ A G Y+FCFSNEFSTF+HKTVYFDFQVG++PP+ P N Sbjct: 73 QGNTIYRETKKQYDSFTYRAEVKGVYQFCFSNEFSTFSHKTVYFDFQVGDEPPILPDMGN 132 Query: 140 RVSALTQMESACVSIHEALKSVIDYQTHFRLREAQGRSRAEDLNTRVAYWSVGEALILLV 199 RV+ALTQMESACV+IHEALK+VID QTH+RLREAQ R+RAEDLN+RV+YWSVGE + L V Sbjct: 133 RVTALTQMESACVTIHEALKTVIDSQTHYRLREAQDRARAEDLNSRVSYWSVGETIALFV 192 Query: 200 VSIGQVFLLKSFFSDKRTTTTRVGS 224 VS QV LLKSFF++KR + V S Sbjct: 193 VSFSQVLLLKSFFTEKRPISRAVHS 217 >gi|5803149 coated vesicle membrane protein [Homo sapiens] Length = 201 Score = 123 bits (309), Expect = 1e-28 Identities = 64/173 (36%), Positives = 97/173 (56%), Gaps = 1/173 (0%) Query: 44 NAKQCFYEDIAQGTKCTLEFQVITGGHYDVDCRLEDPDGKVLYKEMKKQYDSFTFTASKN 103 +A++CF+E + GTK L F+V GG D+D + PD K +YK ++ +TF A + Sbjct: 28 HAEECFFERVTSGTKMGLIFEVAEGGFLDIDVEITGPDNKGIYKGDRESSGKYTFAAHMD 87 Query: 104 GTYKFCFSNEFSTFTHKTVYFDFQVGEDPPLFPSENRVSALTQMESACVSIHEALKSVID 163 GTYKFCFSN ST T K V F +GE P E ++E + A+ +V Sbjct: 88 GTYKFCFSNRMSTMTPKIVMFTIDIGEAPKGQDMETEAHQ-NKLEEMINELAVAMTAVKH 146 Query: 164 YQTHFRLREAQGRSRAEDLNTRVAYWSVGEALILLVVSIGQVFLLKSFFSDKR 216 Q + +RE R+ ++ N+RV WS EAL+L+ +++GQ++ LK FF +R Sbjct: 147 EQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRR 199 >gi|5803040 interleukin 1 receptor-like 1 ligand precursor [Homo sapiens] Length = 227 Score = 106 bits (265), Expect = 1e-23 Identities = 75/218 (34%), Positives = 100/218 (45%), Gaps = 19/218 (8%) Query: 22 LALLLLVPGP--GGAS-------EITFELPDNAKQCFYEDIAQGTKCTLEFQVITGGHYD 72 LAL LL+P GGA E TF LP KQCFY+ E+QVI G D Sbjct: 10 LALWLLMPPVEVGGAGPPPIQDGEFTFLLPAGRKQCFYQSAPANASLETEYQVIGGAGLD 69 Query: 73 VDCRLEDPDGKVLYKEMKKQYDSFTFTASKNGTYKFCFSNEFSTFTHKTVYFDF------ 126 VD LE P G +L E +K T ++ G YK CF N FST + K V+F+ Sbjct: 70 VDFTLESPQGVLLVSESRKADGVHTVEPTEAGDYKLCFDNSFSTISEKLVFFELIFDSLQ 129 Query: 127 ----QVGEDPPLFPSENRVSALTQMESACVSIHEALKSVIDYQTHFRLREAQGRSRAEDL 182 G + P E + ++ + ++ L+ I T R EA+ R+ E Sbjct: 130 DDEEVEGWAEAVEPEEMLDVKMEDIKESIETMRTRLERSIQMLTLLRAFEARDRNLQEGN 189 Query: 183 NTRVAYWSVGEALILLVVSIGQVFLLKSFFSDKRTTTT 220 RV +WS +LL+V++ QV LK FF DKR T Sbjct: 190 LERVNFWSAVNVAVLLLVAVLQVCTLKRFFQDKRPVPT 227 >gi|19923442 transmembrane emp24 protein transport domain containing 5 [Homo sapiens] Length = 229 Score = 104 bits (259), Expect = 7e-23 Identities = 70/220 (31%), Positives = 110/220 (50%), Gaps = 23/220 (10%) Query: 21 LLALL--LLVPGPGGA-----SEITFELPDNAKQCFYEDIAQGTKCTLEFQVITGGHYDV 73 LLA L +L+PG G S+ TF LP K+CFY+ + +E+QV+ G D+ Sbjct: 13 LLAALPPVLLPGAAGFTPSLDSDFTFTLPAGQKECFYQPMPLKASLEIEYQVLDGAGLDI 72 Query: 74 DCRLEDPDGKVLYKEMKKQYDSFTFTASKNGTYKFCFSNEFSTFTHKTVYFDF---QVGE 130 D L P+GK L E +K D ++ G Y FCF N FST + K ++F+ +GE Sbjct: 73 DFHLASPEGKTLVFEQRKS-DGVHTVETEVGDYMFCFDNTFSTISEKVIFFELILDNMGE 131 Query: 131 DPPLFPSENRVSALTQMESACVSIHEALKSVIDYQTH----------FRLREAQGRSRAE 180 E+ +T + + + + L+S+ ++ R EA+ R+ E Sbjct: 132 QAQ--EQEDWKKYITGTDILDMKLEDILESINSIKSRLSKSGHIQILLRAFEARDRNIQE 189 Query: 181 DLNTRVAYWSVGEALILLVVSIGQVFLLKSFFSDKRTTTT 220 RV +WS+ ++++VVS QV++LKS F DKR + T Sbjct: 190 SNFDRVNFWSMVNLVVMVVVSAIQVYMLKSLFEDKRKSRT 229 >gi|33457308 transmembrane emp24 protein transport domain containing 4 [Homo sapiens] Length = 227 Score = 82.8 bits (203), Expect = 2e-16 Identities = 61/214 (28%), Positives = 96/214 (44%), Gaps = 24/214 (11%) Query: 23 ALLLLVPGPGGASEITFELPDNAKQCFYEDIAQGTKCTLEFQVIT--------------- 67 ALLLL GA + F + + K+CF E+I T ++ Sbjct: 16 ALLLLALCATGAQGLYFHIGETEKRCFIEEIPDETMVIGNYRTQMWDKQKEVFLPSTPGL 75 Query: 68 GGHYDVDCRLEDPDGKVLYKEMKKQYDSFTFTASKNGTYKFCF---SNEFSTFT--HKTV 122 G H +V +DPDGKV+ FTFT+ G ++ C S + F V Sbjct: 76 GMHVEV----KDPDGKVVLSRQYGSEGRFTFTSHTPGDHQICLHSNSTRMALFAGGKLRV 131 Query: 123 YFDFQVGEDPPLFPSENRVSALTQMESACVSIHEALKSVIDYQTHFRLREAQGRSRAEDL 182 + D QVGE +P LT+++ + + ++ + Q + R RE + R +E Sbjct: 132 HLDIQVGEHANNYPEIAAKDKLTELQLRARQLLDQVEQIQKEQDYQRYREERFRLTSEST 191 Query: 183 NTRVAYWSVGEALILLVVSIGQVFLLKSFFSDKR 216 N RV +WS+ + +IL++ I Q+ LKSFF K+ Sbjct: 192 NQRVLWWSIAQTVILILTGIWQMRHLKSFFEAKK 225 >gi|39725636 transmembrane emp24 protein transport domain containing 9 [Homo sapiens] Length = 235 Score = 78.6 bits (192), Expect = 4e-15 Identities = 67/232 (28%), Positives = 106/232 (45%), Gaps = 27/232 (11%) Query: 2 PRPGSAQRWAAVAGRWGCRLLALLLLVPGPGGASEITFELPDNAKQCFYEDIAQGT---- 57 PRPG+ GR R L L+L + G A + F + + K+CF E+I T Sbjct: 12 PRPGTG------LGRV-MRTLLLVLWLATRGSA--LYFHIGETEKKCFIEEIPDETMVIG 62 Query: 58 --------KCTLEFQVITGGHYDVDCRLEDPDGKVLYKEMKKQYDSFTFTASKNGTYKFC 109 K E+Q T G + ++DP+ KV+ FTFT+ G ++ C Sbjct: 63 NYRTQLYDKQREEYQPATPG-LGMFVEVKDPEDKVILARQYGSEGRFTFTSHTPGEHQIC 121 Query: 110 F---SNEFSTFTHKT--VYFDFQVGEDPPLFPSENRVSALTQMESACVSIHEALKSVIDY 164 S +FS F V+ D QVGE + L++++ + E ++ + Sbjct: 122 LHSNSTKFSLFAGGMLRVHLDIQVGEHANDYAEIAAKDKLSELQLRVRQLVEQVEQIQKE 181 Query: 165 QTHFRLREAQGRSRAEDLNTRVAYWSVGEALILLVVSIGQVFLLKSFFSDKR 216 Q + R RE + R +E N RV +WS+ + LIL+ + + Q+ LKSFF K+ Sbjct: 182 QNYQRWREERFRQTSESTNQRVLWWSILQTLILVAIGVWQMRHLKSFFEAKK 233 >gi|98986464 transmembrane emp24 domain-containing protein 10 precursor [Homo sapiens] Length = 219 Score = 73.2 bits (178), Expect = 2e-13 Identities = 50/201 (24%), Positives = 91/201 (45%), Gaps = 5/201 (2%) Query: 21 LLALLLLVPGPGGASEITFELPDNAKQCFYEDIAQGTKCTLEFQVIT----GGHYDVDCR 76 L LLL + GP I+F LP N+++C E+I + T +++ G + Sbjct: 16 LALLLLFLLGPRLVLAISFHLPINSRKCLREEIHKDLLVTGAYEISDQSGGAGGLRSHLK 75 Query: 77 LEDPDGKVLYKEMKKQYDSFTFTASKNGTYKFCFSNEFS-TFTHKTVYFDFQVGEDPPLF 135 + D G +LY + F FT ++ CF ++ + + V D + G + + Sbjct: 76 ITDSAGHILYSKEDATKGKFAFTTEDYDMFEVCFESKGTGRIPDQLVILDMKHGVEAKNY 135 Query: 136 PSENRVSALTQMESACVSIHEALKSVIDYQTHFRLREAQGRSRAEDLNTRVAYWSVGEAL 195 +V L +E + + +S+++ + + RE + R E NTRV Y+S+ Sbjct: 136 EEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMF 195 Query: 196 ILLVVSIGQVFLLKSFFSDKR 216 L+ ++ QVF L+ FF K+ Sbjct: 196 CLIGLATWQVFYLRRFFKAKK 216 >gi|21389573 transmembrane emp24 protein transport domain containing 6 [Homo sapiens] Length = 240 Score = 47.4 bits (111), Expect = 1e-05 Identities = 42/192 (21%), Positives = 80/192 (41%), Gaps = 14/192 (7%) Query: 41 LPDNAKQCFYEDIAQGTKC--TLEFQVITGGHYD--VDCRLEDPDGKVLYKEMKKQYDSF 96 +P +CF++ Q + E Q G +D V +P G L + Sbjct: 48 IPPGGTECFWQFAHQTGYFYFSCEVQRTVGMSHDRHVAATAHNPQG-FLIDTSQGVRGQI 106 Query: 97 TFTASKNGTYKFCFSNEFSTFTHKTVYFDFQVGEDPPLFPSENRVSALTQMESACVSIHE 156 F+ + G Y+ C SN+ + F VY +F V + P ++++ Q+ +I + Sbjct: 107 NFSTQETGFYQLCLSNQHNHFGSVQVYLNFGVFYEGP--ETDHKQKERKQLNDTLDAIED 164 Query: 157 ALKSVID-------YQTHFRLREAQGRSRAEDLNTRVAYWSVGEALILLVVSIGQVFLLK 209 + V + Y R+R+ + V +WS ++L++++ I Q++ LK Sbjct: 165 GTQKVQNNIFHMWRYYNFARMRKMADFFLIQSNYNYVNWWSTAQSLVIILSGILQLYFLK 224 Query: 210 SFFSDKRTTTTR 221 F+ TT T+ Sbjct: 225 RLFNVPTTTDTK 236 >gi|53729352 WD repeat-containing protein 1 isoform 2 [Homo sapiens] Length = 466 Score = 30.4 bits (67), Expect = 1.3 Identities = 32/113 (28%), Positives = 52/113 (46%), Gaps = 8/113 (7%) Query: 99 TASKNGTYKFCFSNEFSTFTHKTVYFDFQVGEDPPLFPS--ENRVSALTQMESACVSIHE 156 T KNG + +S + Y+D + GE+ N+VS +T ES + I Sbjct: 187 TVHKNGGKSYIYSGSHDGHIN---YWDSETGENDSFAGKGHTNQVSRMTVDESGQL-ISC 242 Query: 157 ALKSVIDYQTHFRLREAQGRSRAEDLNTRVAYWSVGEALILLVVSIGQVFLLK 209 ++ + Y T LR+ G+ + L+ + +VG +VV IGQ+ LLK Sbjct: 243 SMDDTVRY-TSLMLRDYSGQGVVK-LDVQPKCVAVGPGGYAVVVCIGQIVLLK 293 >gi|9257257 WD repeat-containing protein 1 isoform 1 [Homo sapiens] Length = 606 Score = 30.4 bits (67), Expect = 1.3 Identities = 32/113 (28%), Positives = 52/113 (46%), Gaps = 8/113 (7%) Query: 99 TASKNGTYKFCFSNEFSTFTHKTVYFDFQVGEDPPLFPS--ENRVSALTQMESACVSIHE 156 T KNG + +S + Y+D + GE+ N+VS +T ES + I Sbjct: 327 TVHKNGGKSYIYSGSHDGHIN---YWDSETGENDSFAGKGHTNQVSRMTVDESGQL-ISC 382 Query: 157 ALKSVIDYQTHFRLREAQGRSRAEDLNTRVAYWSVGEALILLVVSIGQVFLLK 209 ++ + Y T LR+ G+ + L+ + +VG +VV IGQ+ LLK Sbjct: 383 SMDDTVRY-TSLMLRDYSGQGVVK-LDVQPKCVAVGPGGYAVVVCIGQIVLLK 433 >gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo sapiens] Length = 824 Score = 29.3 bits (64), Expect = 2.8 Identities = 23/66 (34%), Positives = 33/66 (50%), Gaps = 8/66 (12%) Query: 15 GRWGCRLLALLLLVPGPGGASEITFELPDNAKQ-CFYEDIAQGTKCTLE------FQVIT 67 G W RLL+LLLL G+ ++ + +P+ AK F IAQ LE F+V + Sbjct: 10 GAW-TRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVAS 68 Query: 68 GGHYDV 73 H D+ Sbjct: 69 KRHGDL 74 >gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens] Length = 948 Score = 29.3 bits (64), Expect = 2.8 Identities = 23/66 (34%), Positives = 33/66 (50%), Gaps = 8/66 (12%) Query: 15 GRWGCRLLALLLLVPGPGGASEITFELPDNAKQ-CFYEDIAQGTKCTLE------FQVIT 67 G W RLL+LLLL G+ ++ + +P+ AK F IAQ LE F+V + Sbjct: 10 GAW-TRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVAS 68 Query: 68 GGHYDV 73 H D+ Sbjct: 69 KRHGDL 74 >gi|4885631 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 [Homo sapiens] Length = 1138 Score = 28.5 bits (62), Expect = 4.9 Identities = 17/50 (34%), Positives = 24/50 (48%), Gaps = 4/50 (8%) Query: 29 PGPGGASEITFELPDNAKQCFYEDIAQGTKCTLEFQVITGGHYDVDCRLE 78 PG G +TF LPD C +G++C + GH+ DCRL+ Sbjct: 273 PGISGCRGLTFCLPD-PYGCSCGSGWRGSQCQ---EACAPGHFGADCRLQ 318 >gi|239748723 PREDICTED: hypothetical protein XP_002346783 [Homo sapiens] Length = 541 Score = 27.7 bits (60), Expect = 8.3 Identities = 14/39 (35%), Positives = 20/39 (51%) Query: 21 LLALLLLVPGPGGASEITFELPDNAKQCFYEDIAQGTKC 59 LL L +PGPG A+ T P+ A Y++ +G C Sbjct: 111 LLPKLPALPGPGAAATHTRMPPEQALMGEYQETPEGAPC 149 >gi|239743851 PREDICTED: hypothetical protein [Homo sapiens] Length = 181 Score = 27.7 bits (60), Expect = 8.3 Identities = 17/41 (41%), Positives = 19/41 (46%), Gaps = 7/41 (17%) Query: 1 MPRPGSAQRWAAVAGRWGCRLLALLLLVPGPGGASEITFEL 41 +P PG VA W C LAL L PGPG A + L Sbjct: 143 LPFPG-------VALPWPCPALALALPYPGPGSALTLALVL 176 >gi|239743848 PREDICTED: hypothetical protein [Homo sapiens] Length = 181 Score = 27.7 bits (60), Expect = 8.3 Identities = 17/41 (41%), Positives = 19/41 (46%), Gaps = 7/41 (17%) Query: 1 MPRPGSAQRWAAVAGRWGCRLLALLLLVPGPGGASEITFEL 41 +P PG VA W C LAL L PGPG A + L Sbjct: 143 LPFPG-------VALPWPCPALALALPYPGPGSALTLALVL 176 >gi|239743746 PREDICTED: hypothetical protein [Homo sapiens] Length = 181 Score = 27.7 bits (60), Expect = 8.3 Identities = 17/41 (41%), Positives = 19/41 (46%), Gaps = 7/41 (17%) Query: 1 MPRPGSAQRWAAVAGRWGCRLLALLLLVPGPGGASEITFEL 41 +P PG VA W C LAL L PGPG A + L Sbjct: 143 LPFPG-------VALPWPCPALALALPYPGPGSALTLALVL 176 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.321 0.136 0.414 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 8,880,243 Number of Sequences: 37866 Number of extensions: 384162 Number of successful extensions: 788 Number of sequences better than 10.0: 18 Number of HSP's better than 10.0 without gapping: 10 Number of HSP's successfully gapped in prelim test: 8 Number of HSP's that attempted gapping in prelim test: 767 Number of HSP's gapped (non-prelim): 18 length of query: 224 length of database: 18,247,518 effective HSP length: 98 effective length of query: 126 effective length of database: 14,536,650 effective search space: 1831617900 effective search space used: 1831617900 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.