Search of human proteins with 32967607

Search of human proteins with 32967607

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|32967607 glutathione peroxidase 2 [Homo sapiens]
         (190 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|32967607 glutathione peroxidase 2 [Homo sapiens]                   393   e-110
gi|41406084 glutathione peroxidase 1 isoform 1 [Homo sapiens]         256   1e-68
gi|4557629 glutathione peroxidase 5 isoform 1 precursor [Homo sa...   154   6e-38
gi|6006001 glutathione peroxidase 3 precursor [Homo sapiens]          146   9e-36
gi|33186887 glutathione peroxidase 6 [Homo sapiens]                   138   3e-33
gi|90903240 glutathione peroxidase 4 isoform C precursor [Homo s...    92   3e-19
gi|75709200 glutathione peroxidase 4 isoform A precursor [Homo s...    92   3e-19
gi|41406082 glutathione peroxidase 1 isoform 2 [Homo sapiens]          87   9e-18
gi|15618997 glutathione peroxidase 7 [Homo sapiens]                    86   1e-17
gi|90903238 glutathione peroxidase 4 isoform B precursor [Homo s...    82   3e-16
gi|192455698 glutathione peroxidase 8 [Homo sapiens]                   78   5e-15
gi|126116589 fibrocystin L [Homo sapiens]                              37   0.013
gi|40316837 ATPase, class I, type 8B, member 2 isoform a [Homo s...    32   0.25 
gi|221625538 MORC family CW-type zinc finger 1 [Homo sapiens]          28   4.8  
gi|171460934 protein phosphatase 1M isoform b [Homo sapiens]           27   8.1  
gi|171460932 protein phosphatase 1M isoform a [Homo sapiens]           27   8.1  

>gi|32967607 glutathione peroxidase 2 [Homo sapiens]
          Length = 190

 Score =  393 bits (1009), Expect = e-110
 Identities = 190/190 (100%), Positives = 190/190 (100%)

Query: 1   MAFIAKSFYDLSAISLDGEKVDFNTFRGRAVLIENVASLUGTTTRDFTQLNELQCRFPRR 60
           MAFIAKSFYDLSAISLDGEKVDFNTFRGRAVLIENVASL GTTTRDFTQLNELQCRFPRR
Sbjct: 1   MAFIAKSFYDLSAISLDGEKVDFNTFRGRAVLIENVASLUGTTTRDFTQLNELQCRFPRR 60

Query: 61  LVVLGFPCNQFGHQENCQNEEILNSLKYVRPGGGYQPTFTLVQKCEVNGQNEHPVFAYLK 120
           LVVLGFPCNQFGHQENCQNEEILNSLKYVRPGGGYQPTFTLVQKCEVNGQNEHPVFAYLK
Sbjct: 61  LVVLGFPCNQFGHQENCQNEEILNSLKYVRPGGGYQPTFTLVQKCEVNGQNEHPVFAYLK 120

Query: 121 DKLPYPYDDPFSLMTDPKLIIWSPVRRSDVAWNFEKFLIGPEGEPFRRYSRTFPTINIEP 180
           DKLPYPYDDPFSLMTDPKLIIWSPVRRSDVAWNFEKFLIGPEGEPFRRYSRTFPTINIEP
Sbjct: 121 DKLPYPYDDPFSLMTDPKLIIWSPVRRSDVAWNFEKFLIGPEGEPFRRYSRTFPTINIEP 180

Query: 181 DIKRLLKVAI 190
           DIKRLLKVAI
Sbjct: 181 DIKRLLKVAI 190


>gi|41406084 glutathione peroxidase 1 isoform 1 [Homo sapiens]
          Length = 203

 Score =  256 bits (653), Expect = 1e-68
 Identities = 128/187 (68%), Positives = 148/187 (79%), Gaps = 2/187 (1%)

Query: 2   AFIAKSFYDLSAISL-DGEKVDFNTFRGRAVLIENVASLUGTTTRDFTQLNELQCRF-PR 59
           A  A+S Y  SA  L  GE V   + RG+ +LIENVASL GTT RD+TQ+NELQ R  PR
Sbjct: 10  AAAAQSVYAFSARPLAGGEPVSLGSLRGKVLLIENVASLUGTTVRDYTQMNELQRRLGPR 69

Query: 60  RLVVLGFPCNQFGHQENCQNEEILNSLKYVRPGGGYQPTFTLVQKCEVNGQNEHPVFAYL 119
            LVVLGFPCNQFGHQEN +NEEILNSLKYVRPGGG++P F L +KCEVNG   HP+FA+L
Sbjct: 70  GLVVLGFPCNQFGHQENAKNEEILNSLKYVRPGGGFEPNFMLFEKCEVNGAGAHPLFAFL 129

Query: 120 KDKLPYPYDDPFSLMTDPKLIIWSPVRRSDVAWNFEKFLIGPEGEPFRRYSRTFPTINIE 179
           ++ LP P DD  +LMTDPKLI WSPV R+DVAWNFEKFL+GP+G P RRYSR F TI+IE
Sbjct: 130 REALPAPSDDATALMTDPKLITWSPVCRNDVAWNFEKFLVGPDGVPLRRYSRRFQTIDIE 189

Query: 180 PDIKRLL 186
           PDI+ LL
Sbjct: 190 PDIEALL 196


>gi|4557629 glutathione peroxidase 5 isoform 1 precursor [Homo
           sapiens]
          Length = 221

 Score =  154 bits (388), Expect = 6e-38
 Identities = 84/183 (45%), Positives = 114/183 (62%), Gaps = 7/183 (3%)

Query: 7   SFYDLSAISLD-GEKVDFNTFRGRAVLIENVASLUGTTTRDFTQLNELQCRF-PRRLVVL 64
           + YD  AI+L+  E V F  + G+ +L  NVA+  G T + + +LN LQ    P  LVVL
Sbjct: 39  TIYDYEAIALNKNEYVSFKQYVGKHILFVNVATYCGLTAQ-YPELNALQEELKPYGLVVL 97

Query: 65  GFPCNQFGHQENCQNEEILNSLKYVRPGGGYQPTFTLVQKCEVNGQNEHPVFAYLKDKLP 124
           GFPCNQFG QE   N+EIL  LKYVRPGGG+ P+F L +K +VNG+ E  VF++LK   P
Sbjct: 98  GFPCNQFGKQEPGDNKEILPGLKYVRPGGGFVPSFQLFEKGDVNGEKEQKVFSFLKHSCP 157

Query: 125 YPYDDPFSLMTDPKLIIWSPVRRSDVAWNFEKFLIGPEGEPFRRYSRTFPTINIEPDIKR 184
           +P +    ++   K I W PV+  D+ WNFEKFL+GP+G P  R+S      +++ DI  
Sbjct: 158 HPSE----ILGTFKSISWDPVKVHDIRWNFEKFLVGPDGIPVMRWSHRATVSSVKTDILA 213

Query: 185 LLK 187
            LK
Sbjct: 214 YLK 216


>gi|6006001 glutathione peroxidase 3 precursor [Homo sapiens]
          Length = 226

 Score =  146 bits (369), Expect = 9e-36
 Identities = 78/181 (43%), Positives = 111/181 (61%), Gaps = 7/181 (3%)

Query: 4   IAKSFYDLSAISLDGEK-VDFNTFRGRAVLIENVASLUGTTTRDFTQLNELQCRF-PRRL 61
           I+ + Y+  A+++DGE+ + F  + G+ VL  NVAS  G T + + +LN LQ    P  L
Sbjct: 36  ISGTIYEYGALTIDGEEYIPFKQYAGKYVLFVNVASYUGLTGQ-YIELNALQEELAPFGL 94

Query: 62  VVLGFPCNQFGHQENCQNEEILNSLKYVRPGGGYQPTFTLVQKCEVNGQNEHPVFAYLKD 121
           V+LGFPCNQFG QE  +N EIL +LKYVRPGGG+ P F L +K +VNG+ E   + +LK+
Sbjct: 95  VILGFPCNQFGKQEPGENSEILPTLKYVRPGGGFVPNFQLFEKGDVNGEKEQKFYTFLKN 154

Query: 122 KLPYPYDDPFSLMTDPKLIIWSPVRRSDVAWNFEKFLIGPEGEPFRRYSRTFPTINIEPD 181
             P        L+     + W P++  D+ WNFEKFL+GP+G P  R+       N++ D
Sbjct: 155 SCP----PTSELLGTSDRLFWEPMKVHDIRWNFEKFLVGPDGIPIMRWHHRTTVSNVKMD 210

Query: 182 I 182
           I
Sbjct: 211 I 211


>gi|33186887 glutathione peroxidase 6 [Homo sapiens]
          Length = 221

 Score =  138 bits (347), Expect = 3e-33
 Identities = 75/186 (40%), Positives = 107/186 (57%), Gaps = 7/186 (3%)

Query: 4   IAKSFYDLSAISLDGEK-VDFNTFRGRAVLIENVASLUGTTTRDFTQLNELQCRFPR-RL 61
           +  + Y+  A++L+GE+ + F  F G+ VL  NVA+  G   + + +LN LQ       +
Sbjct: 36  VTGTIYEYGALTLNGEEYIQFKQFAGKHVLFVNVAAYUGLAAQ-YPELNALQEELKNFGV 94

Query: 62  VVLGFPCNQFGHQENCQNEEILNSLKYVRPGGGYQPTFTLVQKCEVNGQNEHPVFAYLKD 121
           +VL FPCNQFG QE   N EIL  LKYV PG G+ P+F L +K +VNG+ E  VF +LK+
Sbjct: 95  IVLAFPCNQFGKQEPGTNSEILLGLKYVCPGSGFVPSFQLFEKGDVNGEKEQKVFTFLKN 154

Query: 122 KLPYPYDDPFSLMTDPKLIIWSPVRRSDVAWNFEKFLIGPEGEPFRRYSRTFPTINIEPD 181
             P   D    L+     + W P++  D+ WNFEKFL+GP+G P   +    P   ++ D
Sbjct: 155 SCPPTSD----LLGSSSQLFWEPMKVHDIRWNFEKFLVGPDGVPVMHWFHQAPVSTVKSD 210

Query: 182 IKRLLK 187
           I   LK
Sbjct: 211 ILEYLK 216


>gi|90903240 glutathione peroxidase 4 isoform C precursor [Homo
           sapiens]
          Length = 234

 Score = 92.0 bits (227), Expect = 3e-19
 Identities = 61/179 (34%), Positives = 89/179 (49%), Gaps = 24/179 (13%)

Query: 5   AKSFYDLSAISLDGEKVDFNTFRGRAVLIENVASLUGTTTRDFTQLNELQCRFPR-RLVV 63
           A+S ++ SA  +DG  V+ + +RG   ++ NVAS  G T  ++TQL +L  R+    L +
Sbjct: 75  ARSMHEFSAKDIDGHMVNLDKYRGFVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRI 134

Query: 64  LGFPCNQFGHQENCQNEEILNSLKYVRPGGGYQPTFTLVQKCEVNGQNEHPVFAYLKDKL 123
           L FPCNQFG QE   NEEI           GY   F +  K  VNG + HP++ ++K   
Sbjct: 135 LAFPCNQFGKQEPGSNEEIKEF------AAGYNVKFDMFSKICVNGDDAHPLWKWMK--- 185

Query: 124 PYPYDDPFSLMTDPKLIIWSPVRRSDVAWNFEKFLIGPEGEPFRRYSRTFPTINIEPDI 182
                    +    K I+ + ++     WNF KFLI   G   +RY      + IE D+
Sbjct: 186 ---------IQPKGKGILGNAIK-----WNFTKFLIDKNGCVVKRYGPMEEPLVIEKDL 230


>gi|75709200 glutathione peroxidase 4 isoform A precursor [Homo
           sapiens]
          Length = 197

 Score = 92.0 bits (227), Expect = 3e-19
 Identities = 61/179 (34%), Positives = 89/179 (49%), Gaps = 24/179 (13%)

Query: 5   AKSFYDLSAISLDGEKVDFNTFRGRAVLIENVASLUGTTTRDFTQLNELQCRFPR-RLVV 63
           A+S ++ SA  +DG  V+ + +RG   ++ NVAS  G T  ++TQL +L  R+    L +
Sbjct: 38  ARSMHEFSAKDIDGHMVNLDKYRGFVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRI 97

Query: 64  LGFPCNQFGHQENCQNEEILNSLKYVRPGGGYQPTFTLVQKCEVNGQNEHPVFAYLKDKL 123
           L FPCNQFG QE   NEEI           GY   F +  K  VNG + HP++ ++K   
Sbjct: 98  LAFPCNQFGKQEPGSNEEIKEF------AAGYNVKFDMFSKICVNGDDAHPLWKWMK--- 148

Query: 124 PYPYDDPFSLMTDPKLIIWSPVRRSDVAWNFEKFLIGPEGEPFRRYSRTFPTINIEPDI 182
                    +    K I+ + ++     WNF KFLI   G   +RY      + IE D+
Sbjct: 149 ---------IQPKGKGILGNAIK-----WNFTKFLIDKNGCVVKRYGPMEEPLVIEKDL 193


>gi|41406082 glutathione peroxidase 1 isoform 2 [Homo sapiens]
          Length = 98

 Score = 87.0 bits (214), Expect = 9e-18
 Identities = 49/75 (65%), Positives = 55/75 (73%), Gaps = 2/75 (2%)

Query: 2  AFIAKSFYDLSAISL-DGEKVDFNTFRGRAVLIENVASLUGTTTRDFTQLNELQCRF-PR 59
          A  A+S Y  SA  L  GE V   + RG+ +LIENVASL GTT RD+TQ+NELQ R  PR
Sbjct: 10 AAAAQSVYAFSARPLAGGEPVSLGSLRGKVLLIENVASLUGTTVRDYTQMNELQRRLGPR 69

Query: 60 RLVVLGFPCNQFGHQ 74
           LVVLGFPCNQFGHQ
Sbjct: 70 GLVVLGFPCNQFGHQ 84


>gi|15618997 glutathione peroxidase 7 [Homo sapiens]
          Length = 187

 Score = 86.3 bits (212), Expect = 1e-17
 Identities = 55/186 (29%), Positives = 80/186 (43%), Gaps = 29/186 (15%)

Query: 6   KSFYDLSAISLDGEKVDFNTFRGRAVLIENVASLUGTTTRDFTQLNELQCRF-PRRLVVL 64
           + FYD  A+++ G+ V    +RG   L+ NVAS  G T + +  L +LQ    P    VL
Sbjct: 23  QDFYDFKAVNIRGKLVSLEKYRGSVSLVVNVASECGFTDQHYRALQQLQRDLGPHHFNVL 82

Query: 65  GFPCNQFGHQENCQNEEILNSLKYVRPGGGYQPTFTLVQKCEVNGQNEHPVFAYLKDKLP 124
            FPCNQFG QE   N+EI +  +       Y  +F +  K  V G   HP F YL     
Sbjct: 83  AFPCNQFGQQEPDSNKEIESFARRT-----YSVSFPMFSKIAVTGTGAHPAFKYL----- 132

Query: 125 YPYDDPFSLMTDPKLIIWSPVRRSDVAWNFEKFLIGPEGEPFRRYSRTFPTINIEPDIKR 184
                             +     +  WNF K+L+ P+G+    +  T     + P I  
Sbjct: 133 ------------------AQTSGKEPTWNFWKYLVAPDGKVVGAWDPTVSVEEVRPQITA 174

Query: 185 LLKVAI 190
           L++  I
Sbjct: 175 LVRKLI 180


>gi|90903238 glutathione peroxidase 4 isoform B precursor [Homo
           sapiens]
          Length = 227

 Score = 82.0 bits (201), Expect = 3e-16
 Identities = 53/154 (34%), Positives = 78/154 (50%), Gaps = 24/154 (15%)

Query: 5   AKSFYDLSAISLDGEKVDFNTFRGRAVLIENVASLUGTTTRDFTQLNELQCRFPR-RLVV 63
           A+S ++ SA  +DG  V+ + +RG   ++ NVAS  G T  ++TQL +L  R+    L +
Sbjct: 38  ARSMHEFSAKDIDGHMVNLDKYRGFVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRI 97

Query: 64  LGFPCNQFGHQENCQNEEILNSLKYVRPGGGYQPTFTLVQKCEVNGQNEHPVFAYLKDKL 123
           L FPCNQFG QE   NEEI           GY   F +  K  VNG + HP++ ++K   
Sbjct: 98  LAFPCNQFGKQEPGSNEEIKEF------AAGYNVKFDMFSKICVNGDDAHPLWKWMK--- 148

Query: 124 PYPYDDPFSLMTDPKLIIWSPVRRSDVAWNFEKF 157
                    +    K I+ + ++     WNF KF
Sbjct: 149 ---------IQPKGKGILGNAIK-----WNFTKF 168


>gi|192455698 glutathione peroxidase 8 [Homo sapiens]
          Length = 209

 Score = 77.8 bits (190), Expect = 5e-15
 Identities = 53/185 (28%), Positives = 77/185 (41%), Gaps = 29/185 (15%)

Query: 7   SFYDLSAISLDGEKVDFNTFRGRAVLIENVASLUGTTTRDFTQLNELQCRF-PRRLVVLG 65
           SFY        G  V    ++G+  L+ NVAS    T R++  L EL   F P    VL 
Sbjct: 46  SFYAFEVKDAKGRTVSLEKYKGKVSLVVNVASDCQLTDRNYLGLKELHKEFGPSHFSVLA 105

Query: 66  FPCNQFGHQENCQNEEILNSLKYVRPGGGYQPTFTLVQKCEVNGQNEHPVFAYLKDKLPY 125
           FPCNQFG  E   ++E+ +  +       Y  TF +  K ++ G    P F +L D    
Sbjct: 106 FPCNQFGESEPRPSKEVESFARK-----NYGVTFPIFHKIKILGSEGEPAFRFLVDS--- 157

Query: 126 PYDDPFSLMTDPKLIIWSPVRRSDVAWNFEKFLIGPEGEPFRRYSRTFPTINIEPDIKRL 185
                                + +  WNF K+L+ PEG+  + +    P   I PDI  L
Sbjct: 158 --------------------SKKEPRWNFWKYLVNPEGQVVKFWKPEEPIEVIRPDIAAL 197

Query: 186 LKVAI 190
           ++  I
Sbjct: 198 VRQVI 202


>gi|126116589 fibrocystin L [Homo sapiens]
          Length = 4243

 Score = 36.6 bits (83), Expect = 0.013
 Identities = 43/153 (28%), Positives = 64/153 (41%), Gaps = 17/153 (11%)

Query: 23  FNTFRGRAVLIENVASLUGTTTRDFTQLNELQCRFPRRLVVLGFPCNQFGHQEN---CQN 79
           F T+    ++  +  S+ G TT   +     Q  FP R++V G PC+     EN   C+ 
Sbjct: 266 FQTYAEVTMIFPSQGSIRGGTTLTISGRFFDQTDFPVRVLVGGEPCDILNVTENSICCKT 325

Query: 80  EEILNSLKYVRPGGGYQPTFTLVQKCEVNGQNEHPVFAYLKDKLPYPYDDPFSL---MTD 136
               + LK V PGG          K EV   N  P+   L++ L Y    P  +     D
Sbjct: 326 PPKPHILKTVYPGG-------RGLKLEV-WNNSRPI--RLEEILEYNEKTPGYMGASWVD 375

Query: 137 PKLIIWSPVRRSDVAWNFEKFLIGPEGEPFRRY 169
               IW   + + VA  F  FL+ P+ + +R Y
Sbjct: 376 SASYIWLMEQDTFVA-RFSGFLVAPDSDVYRFY 407


>gi|40316837 ATPase, class I, type 8B, member 2 isoform a [Homo
           sapiens]
          Length = 1223

 Score = 32.3 bits (72), Expect = 0.25
 Identities = 22/73 (30%), Positives = 31/73 (42%), Gaps = 8/73 (10%)

Query: 79  NEEILNSLKYVRPG--GGYQPTFTLVQKCEVNGQNEHPVFAYLKDKL-----PYPYDDPF 131
           NEE L  ++Y+     G       +  KC +NG +   VF  L  K      P P D  F
Sbjct: 413 NEE-LGQVEYIFSDKTGTLTQNIMVFNKCSINGHSYGDVFDVLGHKAELGERPEPVDFSF 471

Query: 132 SLMTDPKLIIWSP 144
           + + D K + W P
Sbjct: 472 NPLADKKFLFWDP 484


>gi|221625538 MORC family CW-type zinc finger 1 [Homo sapiens]
          Length = 984

 Score = 28.1 bits (61), Expect = 4.8
 Identities = 11/23 (47%), Positives = 16/23 (69%)

Query: 68  CNQFGHQENCQNEEILNSLKYVR 90
           CN+FG+Q +   E+ LNS +Y R
Sbjct: 452 CNEFGYQNDIDVEKPLNSFQYQR 474


>gi|171460934 protein phosphatase 1M isoform b [Homo sapiens]
          Length = 247

 Score = 27.3 bits (59), Expect = 8.1
 Identities = 15/47 (31%), Positives = 21/47 (44%), Gaps = 3/47 (6%)

Query: 121 DKLPYPYDDPFSLMTDPKLIIWSPVRRSDVAWNFEKFLIGPEGEPFR 167
           D+L    DD   + TD    +W  +    VAW    FL G + +P R
Sbjct: 157 DQLELQEDDVVVMATDG---LWDVLSNEQVAWLVRSFLPGNQEDPHR 200


>gi|171460932 protein phosphatase 1M isoform a [Homo sapiens]
          Length = 298

 Score = 27.3 bits (59), Expect = 8.1
 Identities = 15/47 (31%), Positives = 21/47 (44%), Gaps = 3/47 (6%)

Query: 121 DKLPYPYDDPFSLMTDPKLIIWSPVRRSDVAWNFEKFLIGPEGEPFR 167
           D+L    DD   + TD    +W  +    VAW    FL G + +P R
Sbjct: 208 DQLELQEDDVVVMATDG---LWDVLSNEQVAWLVRSFLPGNQEDPHR 251


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.141    0.439 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,557,476
Number of Sequences: 37866
Number of extensions: 357049
Number of successful extensions: 472
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 441
Number of HSP's gapped (non-prelim): 16
length of query: 190
length of database: 18,247,518
effective HSP length: 96
effective length of query: 94
effective length of database: 14,612,382
effective search space: 1373563908
effective search space used: 1373563908
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.