Search of human proteins with 122937500

Search of human proteins with 122937500

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|122937500 unc-119 homolog B [Homo sapiens]
         (251 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|122937500 unc-119 homolog B [Homo sapiens]                         511   e-145
gi|4827048 unc119 (C.elegans) homolog isoform a [Homo sapiens]        273   8e-74
gi|16936535 unc119 (C.elegans) homolog isoform b [Homo sapiens]       218   4e-57
gi|4505671 phosphodiesterase 6D [Homo sapiens]                         40   0.002
gi|45269149 quinolinate phosphoribosyltransferase [Homo sapiens]       33   0.31 
gi|4758156 diacylglycerol kinase, iota [Homo sapiens]                  31   1.2  
gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]          30   1.5  
gi|239752133 PREDICTED: hypothetical protein [Homo sapiens]            30   2.6  
gi|222831660 family with sequence similarity 171, member A2 [Hom...    29   4.4  
gi|33188459 B-Raf [Homo sapiens]                                       29   4.4  
gi|169213727 PREDICTED: hypothetical protein [Homo sapiens]            28   5.8  
gi|4758506 basic helix-loop-helix transcription factor HAND1 [Ho...    28   5.8  
gi|26051273 voltage-gated potassium channel, subfamily H, member...    28   7.6  
gi|4557729 voltage-gated potassium channel, subfamily H, member ...    28   7.6  
gi|12707580 paired-like homeobox 2b [Homo sapiens]                     28   7.6  
gi|26667196 calcium/calmodulin-dependent protein kinase II gamma...    28   7.6  
gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi...    28   7.6  

>gi|122937500 unc-119 homolog B [Homo sapiens]
          Length = 251

 Score =  511 bits (1315), Expect = e-145
 Identities = 251/251 (100%), Positives = 251/251 (100%)

Query: 1   MSGSNPKAAAAASAAGPGGLVAGKEEKKKAGGGVLNRLKARRQAPHHAADDGVGAAVTEQ 60
           MSGSNPKAAAAASAAGPGGLVAGKEEKKKAGGGVLNRLKARRQAPHHAADDGVGAAVTEQ
Sbjct: 1   MSGSNPKAAAAASAAGPGGLVAGKEEKKKAGGGVLNRLKARRQAPHHAADDGVGAAVTEQ 60

Query: 61  ELLALDTIRPEHVLRLSRVTENYLCKPEDNIYSIDFTRFKIRDLETGTVLFEIAKPCVSD 120
           ELLALDTIRPEHVLRLSRVTENYLCKPEDNIYSIDFTRFKIRDLETGTVLFEIAKPCVSD
Sbjct: 61  ELLALDTIRPEHVLRLSRVTENYLCKPEDNIYSIDFTRFKIRDLETGTVLFEIAKPCVSD 120

Query: 121 QEEDEEEGGGDVDISAGRFVRYQFTPAFLRLRTVGATVEFTVGDKPVSNFRMIERHYFRE 180
           QEEDEEEGGGDVDISAGRFVRYQFTPAFLRLRTVGATVEFTVGDKPVSNFRMIERHYFRE
Sbjct: 121 QEEDEEEGGGDVDISAGRFVRYQFTPAFLRLRTVGATVEFTVGDKPVSNFRMIERHYFRE 180

Query: 181 HLLKNFDFDFGFCIPSSRNTCEHIYEFPQLSEDVIRLMIENPYETRSDSFYFVDNKLIMH 240
           HLLKNFDFDFGFCIPSSRNTCEHIYEFPQLSEDVIRLMIENPYETRSDSFYFVDNKLIMH
Sbjct: 181 HLLKNFDFDFGFCIPSSRNTCEHIYEFPQLSEDVIRLMIENPYETRSDSFYFVDNKLIMH 240

Query: 241 NKADYAYNGGQ 251
           NKADYAYNGGQ
Sbjct: 241 NKADYAYNGGQ 251


>gi|4827048 unc119 (C.elegans) homolog isoform a [Homo sapiens]
          Length = 240

 Score =  273 bits (699), Expect = 8e-74
 Identities = 131/182 (71%), Positives = 154/182 (84%), Gaps = 3/182 (1%)

Query: 68  IRPEHVLRLSRVTENYLCKPEDNIYSIDFTRFKIRDLETGTVLFEIAKPCVSDQEEDEEE 127
           I PE VL L R+T +YLC PE+NIY IDF RFKIRD+++GTVLFEI KP VS++      
Sbjct: 60  IGPEDVLGLQRITGDYLCSPEENIYKIDFVRFKIRDMDSGTVLFEIKKPPVSERLPINRR 119

Query: 128 GGGDVDISAGRFVRYQFTPAFLRLRTVGATVEFTVGDKPVSNFRMIERHYFREHLLKNFD 187
              D+D +AGRFVRYQFTPAFLRLR VGATVEFTVGDKPV+NFRMIERHYFR  LLK+FD
Sbjct: 120 ---DLDPNAGRFVRYQFTPAFLRLRQVGATVEFTVGDKPVNNFRMIERHYFRNQLLKSFD 176

Query: 188 FDFGFCIPSSRNTCEHIYEFPQLSEDVIRLMIENPYETRSDSFYFVDNKLIMHNKADYAY 247
           F FGFCIPSS+NTCEHIY+FP LSE++I  MI +PYET+SDSFYFVD++L+MHNKADY+Y
Sbjct: 177 FHFGFCIPSSKNTCEHIYDFPPLSEELISEMIRHPYETQSDSFYFVDDRLVMHNKADYSY 236

Query: 248 NG 249
           +G
Sbjct: 237 SG 238


>gi|16936535 unc119 (C.elegans) homolog isoform b [Homo sapiens]
          Length = 220

 Score =  218 bits (555), Expect = 4e-57
 Identities = 106/147 (72%), Positives = 122/147 (82%), Gaps = 3/147 (2%)

Query: 68  IRPEHVLRLSRVTENYLCKPEDNIYSIDFTRFKIRDLETGTVLFEIAKPCVSDQEEDEEE 127
           I PE VL L R+T +YLC PE+NIY IDF RFKIRD+++GTVLFEI KP VS++      
Sbjct: 60  IGPEDVLGLQRITGDYLCSPEENIYKIDFVRFKIRDMDSGTVLFEIKKPPVSERLPINRR 119

Query: 128 GGGDVDISAGRFVRYQFTPAFLRLRTVGATVEFTVGDKPVSNFRMIERHYFREHLLKNFD 187
              D+D +AGRFVRYQFTPAFLRLR VGATVEFTVGDKPV+NFRMIERHYFR  LLK+FD
Sbjct: 120 ---DLDPNAGRFVRYQFTPAFLRLRQVGATVEFTVGDKPVNNFRMIERHYFRNQLLKSFD 176

Query: 188 FDFGFCIPSSRNTCEHIYEFPQLSEDV 214
           F FGFCIPSS+NTCEHIY+FP LSE++
Sbjct: 177 FHFGFCIPSSKNTCEHIYDFPPLSEEL 203


>gi|4505671 phosphodiesterase 6D [Homo sapiens]
          Length = 150

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 28/107 (26%), Positives = 50/107 (46%), Gaps = 19/107 (17%)

Query: 101 IRDLETGTVLFEIAKPCVSDQEEDEEEGGGDVDISAGRFVRYQFTPA-FLRLRTVGATVE 159
           +RD ETG +L++                 G  D+S          P   L+ + V   + 
Sbjct: 22  LRDAETGKILWQ-----------------GTEDLSVPGVEHEARVPKKILKCKAVSRELN 64

Query: 160 FTVGDKPVSNFRMIERHYFREHLLKNFDFDFGFCIPSSRNTCEHIYE 206
           F+  ++ +  FR+ ++ YF+   L+ + F+FGF IP+S NT + + E
Sbjct: 65  FSSTEQ-MEKFRLEQKVYFKGQCLEEWFFEFGFVIPNSTNTWQSLIE 110


>gi|45269149 quinolinate phosphoribosyltransferase [Homo sapiens]
          Length = 297

 Score = 32.7 bits (73), Expect = 0.31
 Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 9/73 (12%)

Query: 10  AAASAAGPGGLVAGKEEKKKAGGGVLNRLKARRQAPHHA---------ADDGVGAAVTEQ 60
           AA+     GGLV  K+    A GGV   ++A RQA   A           + V AA    
Sbjct: 157 AASHRYDLGGLVMVKDNHVVAAGGVEKAVRAARQAADFALKVEVECSSLQEAVQAAEAGA 216

Query: 61  ELLALDTIRPEHV 73
           +L+ LD  +PE +
Sbjct: 217 DLVLLDNFKPEEL 229


>gi|4758156 diacylglycerol kinase, iota [Homo sapiens]
          Length = 1065

 Score = 30.8 bits (68), Expect = 1.2
 Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 14/78 (17%)

Query: 3   GSNPKAAAAASAAGPGGL----VAGKEEKKKAGGGVLNRLKARRQAPHHAADDGVGAAVT 58
           G++P+ A +A+AAG   L     AG++EK +A    L  L  R+Q  +  A    G    
Sbjct: 86  GADPRGAGSAAAAGAAALDEPAAAGQKEKDEALEEKLRNLTFRKQVSYRKAISRAG---- 141

Query: 59  EQELLALDTIRPEHVLRL 76
                 L  + P H L L
Sbjct: 142 ------LQHLAPAHPLSL 153


>gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]
          Length = 1192

 Score = 30.4 bits (67), Expect = 1.5
 Identities = 16/41 (39%), Positives = 22/41 (53%)

Query: 2   SGSNPKAAAAASAAGPGGLVAGKEEKKKAGGGVLNRLKARR 42
           +G++  AAA A+AAG GG  A       AG G   +L  R+
Sbjct: 230 TGASVSAAATAAAAGGGGSTASTSGGVGAGAGARGKLSPRK 270


>gi|239752133 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 224

 Score = 29.6 bits (65), Expect = 2.6
 Identities = 20/54 (37%), Positives = 26/54 (48%), Gaps = 7/54 (12%)

Query: 3  GSNPKAAAAASAAGPGGLVAGKEEKKKAGGGVLNRLKARRQAPHHAADDGVGAA 56
          GS P     +SA G G  V G+  +   GGGV  R K R +  +  A  G G+A
Sbjct: 18 GSRP-----SSAVGEGSRVPGR--RLDEGGGVQGRWKNRGRGTYRGAGPGAGSA 64


>gi|222831660 family with sequence similarity 171, member A2 [Homo
           sapiens]
          Length = 826

 Score = 28.9 bits (63), Expect = 4.4
 Identities = 25/98 (25%), Positives = 35/98 (35%), Gaps = 8/98 (8%)

Query: 3   GSNPKAAAAASAAGPGGLVAGKEEKKKAGGGVLNRLKARRQAP----HHAADDGVGAAVT 58
           G +     A SA GPGGL  G EE ++   G    L      P    H+    G     T
Sbjct: 436 GESAGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKGAAEGKT 495

Query: 59  EQELLALDTIRPEHVLRLSRVTENYLCKP----EDNIY 92
              LL+    +      L +  +   C      +DN+Y
Sbjct: 496 PDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVY 533


>gi|33188459 B-Raf [Homo sapiens]
          Length = 766

 Score = 28.9 bits (63), Expect = 4.4
 Identities = 19/51 (37%), Positives = 26/51 (50%), Gaps = 9/51 (17%)

Query: 189 DFGFCIPSSRNTCEHIYEFPQLS-------EDVIRLMIENPYETRSDSFYF 232
           DFG     SR +  H  +F QLS        +VIR+  +NPY  +SD + F
Sbjct: 594 DFGLATVKSRWSGSH--QFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAF 642


>gi|169213727 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 235

 Score = 28.5 bits (62), Expect = 5.8
 Identities = 20/57 (35%), Positives = 25/57 (43%), Gaps = 2/57 (3%)

Query: 2  SGSNPKAAAAASAAGPGGLVAGKEEKKKAGGGVLNRLKARRQA--PHHAADDGVGAA 56
          SG  P+A  +  A G G    G ++   A    L+ L A RQA    HA     GAA
Sbjct: 8  SGLRPRADGSTRALGSGSAARGPQKATTARTSTLSMLSAGRQAGFASHAGGAVGGAA 64


>gi|4758506 basic helix-loop-helix transcription factor HAND1 [Homo
           sapiens]
          Length = 215

 Score = 28.5 bits (62), Expect = 5.8
 Identities = 18/57 (31%), Positives = 24/57 (42%)

Query: 3   GSNPKAAAAASAAGPGGLVAGKEEKKKAGGGVLNRLKARRQAPHHAADDGVGAAVTE 59
           G  P AAAAA+A GP         + +A GG L R K           + + +A  E
Sbjct: 60  GPPPAAAAAATAYGPDARPGQSPGRLEALGGRLGRRKGSGPKKERRRTESINSAFAE 116


>gi|26051273 voltage-gated potassium channel, subfamily H, member 2
           isoform c [Homo sapiens]
          Length = 819

 Score = 28.1 bits (61), Expect = 7.6
 Identities = 16/58 (27%), Positives = 26/58 (44%)

Query: 13  SAAGPGGLVAGKEEKKKAGGGVLNRLKARRQAPHHAADDGVGAAVTEQELLALDTIRP 70
           SA GPG   AG   + + GG       +   +P  + D+G G + +   L+   + RP
Sbjct: 566 SALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRP 623


>gi|4557729 voltage-gated potassium channel, subfamily H, member 2
           isoform a [Homo sapiens]
          Length = 1159

 Score = 28.1 bits (61), Expect = 7.6
 Identities = 16/58 (27%), Positives = 26/58 (44%)

Query: 13  SAAGPGGLVAGKEEKKKAGGGVLNRLKARRQAPHHAADDGVGAAVTEQELLALDTIRP 70
           SA GPG   AG   + + GG       +   +P  + D+G G + +   L+   + RP
Sbjct: 906 SALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRP 963


>gi|12707580 paired-like homeobox 2b [Homo sapiens]
          Length = 314

 Score = 28.1 bits (61), Expect = 7.6
 Identities = 20/54 (37%), Positives = 21/54 (38%), Gaps = 2/54 (3%)

Query: 3   GSNPKAAAAASAAGPGGLVAGKEEKKKAGGGVLNRLKARRQAPHHAADDGVGAA 56
           G  P  A A  AAGPGG   G E  K           A   A   AA  G+ AA
Sbjct: 215 GGGPSPAGAPGAAGPGG--PGGEPGKGGAAAAAAAAAAAAAAAAAAAAGGLAAA 266


>gi|26667196 calcium/calmodulin-dependent protein kinase II gamma
           isoform 2 [Homo sapiens]
          Length = 527

 Score = 28.1 bits (61), Expect = 7.6
 Identities = 25/87 (28%), Positives = 40/87 (45%), Gaps = 16/87 (18%)

Query: 4   SNPKAAAAASAAGPGGLVAGKEEKKKAGGGVLNR--------LKARRQAPHHAADDGVGA 55
           S+  A+ AASAAG  G  A     KK+ GGV  R        ++ +    H+A D   G+
Sbjct: 320 SSAPASPAASAAGLAGQAAKSLLNKKSDGGVKKRKSSSSVHLMEPQTTVVHNATDGIKGS 379

Query: 56  -----AVTEQELLALDTIRPEHVLRLS 77
                  TE E L    +R + +++++
Sbjct: 380 TESCNTTTEDEDL---KVRKQEIIKIT 403


>gi|133922600 splicing factor, arginine/serine-rich 16 [Homo
           sapiens]
          Length = 674

 Score = 28.1 bits (61), Expect = 7.6
 Identities = 14/31 (45%), Positives = 18/31 (58%)

Query: 3   GSNPKAAAAASAAGPGGLVAGKEEKKKAGGG 33
           GS+ +AAAAA+AA   G+  GK       GG
Sbjct: 334 GSDEEAAAAAAAAAASGVTTGKPPAPPQPGG 364


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.137    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,897,625
Number of Sequences: 37866
Number of extensions: 450779
Number of successful extensions: 1760
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1744
Number of HSP's gapped (non-prelim): 20
length of query: 251
length of database: 18,247,518
effective HSP length: 100
effective length of query: 151
effective length of database: 14,460,918
effective search space: 2183598618
effective search space used: 2183598618
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.