Guide to the Human Genome
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Search of human proteins with 122937394

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|122937394 iron-sulfur cluster assembly 1 homolog (S.
cerevisiae)-like [Homo sapiens]
         (132 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|122937394 iron-sulfur cluster assembly 1 homolog (S. cerevisi...   263   2e-71
gi|52426768 HESB like domain containing 2 [Homo sapiens]              206   4e-54
gi|160420328 iron-sulfur cluster assembly 2 [Homo sapiens]             34   0.038
gi|122937341 hypothetical protein LOC388960 [Homo sapiens]             30   0.55 
gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo sapi...    28   1.6  
gi|4758112 HLA-B associated transcript 1 [Homo sapiens]                27   4.7  
gi|18375623 HLA-B associated transcript 1 [Homo sapiens]               27   4.7  
gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sap...    27   6.1  
gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sap...    27   6.1  
gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sap...    27   6.1  
gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sap...    27   6.1  
gi|4758942 septin 4 isoform 1 [Homo sapiens]                           27   6.1  
gi|17986247 septin 4 isoform 3 [Homo sapiens]                          27   6.1  
gi|76257392 ubiquitin specific protease 48 isoform b [Homo sapiens]    26   8.0  
gi|52630449 ubiquitin specific protease 48 isoform a [Homo sapiens]    26   8.0  

>gi|122937394 iron-sulfur cluster assembly 1 homolog (S.
           cerevisiae)-like [Homo sapiens]
          Length = 132

 Score =  263 bits (673), Expect = 2e-71
 Identities = 132/132 (100%), Positives = 132/132 (100%)

Query: 1   MSPSLVRATARAVSKRKLQPTRAALTLTPSAVNKIKQLLKDKPEHVGVKVGVRTRGCNGL 60
           MSPSLVRATARAVSKRKLQPTRAALTLTPSAVNKIKQLLKDKPEHVGVKVGVRTRGCNGL
Sbjct: 1   MSPSLVRATARAVSKRKLQPTRAALTLTPSAVNKIKQLLKDKPEHVGVKVGVRTRGCNGL 60

Query: 61  SYTLEYTKTKGDSDEEVIQDGVRVFIEKKAQLTLLGTEMDYVEDKLSSSRKARGSFGAHC 120
           SYTLEYTKTKGDSDEEVIQDGVRVFIEKKAQLTLLGTEMDYVEDKLSSSRKARGSFGAHC
Sbjct: 61  SYTLEYTKTKGDSDEEVIQDGVRVFIEKKAQLTLLGTEMDYVEDKLSSSRKARGSFGAHC 120

Query: 121 RNHVTVTCWKIK 132
           RNHVTVTCWKIK
Sbjct: 121 RNHVTVTCWKIK 132


>gi|52426768 HESB like domain containing 2 [Homo sapiens]
          Length = 129

 Score =  206 bits (524), Expect = 4e-54
 Identities = 106/108 (98%), Positives = 106/108 (98%)

Query: 1   MSPSLVRATARAVSKRKLQPTRAALTLTPSAVNKIKQLLKDKPEHVGVKVGVRTRGCNGL 60
           MS SLVRAT RAVSKRKLQPTRAALTLTPSAVNKIKQLLKDKPEHVGVKVGVRTRGCNGL
Sbjct: 1   MSASLVRATVRAVSKRKLQPTRAALTLTPSAVNKIKQLLKDKPEHVGVKVGVRTRGCNGL 60

Query: 61  SYTLEYTKTKGDSDEEVIQDGVRVFIEKKAQLTLLGTEMDYVEDKLSS 108
           SYTLEYTKTKGDSDEEVIQDGVRVFIEKKAQLTLLGTEMDYVEDKLSS
Sbjct: 61  SYTLEYTKTKGDSDEEVIQDGVRVFIEKKAQLTLLGTEMDYVEDKLSS 108


>gi|160420328 iron-sulfur cluster assembly 2 [Homo sapiens]
          Length = 154

 Score = 33.9 bits (76), Expect = 0.038
 Identities = 22/109 (20%), Positives = 45/109 (41%), Gaps = 3/109 (2%)

Query: 1   MSPSLVRATARAVSKRKLQPTRAALTLTPSAVNKIKQLLKDKPEHVGVKVGVRTRGCNGL 60
           ++ SL     R  S    +     + LT S V ++ ++ +       +++ V   GC+G 
Sbjct: 26  LTASLGPQARREASSSSPEAGEGQIRLTDSCVQRLLEITEGSEF---LRLQVEGGGCSGF 82

Query: 61  SYTLEYTKTKGDSDEEVIQDGVRVFIEKKAQLTLLGTEMDYVEDKLSSS 109
            Y           D    Q G RV ++  +   + G ++D+ ++ + SS
Sbjct: 83  QYKFSLDTVINPDDRVFEQGGARVVVDSDSLAFVKGAQVDFSQELIRSS 131


>gi|122937341 hypothetical protein LOC388960 [Homo sapiens]
          Length = 922

 Score = 30.0 bits (66), Expect = 0.55
 Identities = 26/104 (25%), Positives = 41/104 (39%), Gaps = 2/104 (1%)

Query: 23  AALTLTPSAVNKIKQLLKDKPEHVGVKVGVRTRGCNGLSYTLEYTKTKGDSDEEVIQDGV 82
           +A     ++VNK K    +KP H      +     +G   T    K      EE  Q G 
Sbjct: 535 SATVSNSASVNKAKHS-SNKP-HKAASSRISKTKSHGQEKTKGNRKNSSKKSEESKQSGK 592

Query: 83  RVFIEKKAQLTLLGTEMDYVEDKLSSSRKARGSFGAHCRNHVTV 126
           +V +E+K  +  +  + +  E    + +K R S G H    V V
Sbjct: 593 KVKVEEKQTIPNMKRKKNQPELSQKTLKKPRSSLGMHMLESVQV 636


>gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo
           sapiens]
          Length = 427

 Score = 28.5 bits (62), Expect = 1.6
 Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 2/39 (5%)

Query: 78  IQDGVRVFIEKKAQLTLLGTEMDYVEDKLSSSRKARGSF 116
           +QD + VF++ + +LTL G +  YV  KL  S K R  F
Sbjct: 242 MQDPMEVFVDDETKLTLHGLQQYYV--KLKDSEKNRKLF 278


>gi|4758112 HLA-B associated transcript 1 [Homo sapiens]
          Length = 428

 Score = 26.9 bits (58), Expect = 4.7
 Identities = 14/39 (35%), Positives = 23/39 (58%), Gaps = 2/39 (5%)

Query: 78  IQDGVRVFIEKKAQLTLLGTEMDYVEDKLSSSRKARGSF 116
           +QD + +F++ + +LTL G +  YV  KL  + K R  F
Sbjct: 243 MQDPMEIFVDDETKLTLHGLQQYYV--KLKDNEKNRKLF 279


>gi|18375623 HLA-B associated transcript 1 [Homo sapiens]
          Length = 428

 Score = 26.9 bits (58), Expect = 4.7
 Identities = 14/39 (35%), Positives = 23/39 (58%), Gaps = 2/39 (5%)

Query: 78  IQDGVRVFIEKKAQLTLLGTEMDYVEDKLSSSRKARGSF 116
           +QD + +F++ + +LTL G +  YV  KL  + K R  F
Sbjct: 243 MQDPMEIFVDDETKLTLHGLQQYYV--KLKDNEKNRKLF 279


>gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo
           sapiens]
          Length = 939

 Score = 26.6 bits (57), Expect = 6.1
 Identities = 17/61 (27%), Positives = 28/61 (45%), Gaps = 4/61 (6%)

Query: 43  PEHVGVKVGVRTRGCNGLSYTLEYTKTKGDSDEEVIQDGVRVFIEKKAQLTLLGTEMDYV 102
           P   GVK  V T   +G+S  +      GDS E  +    R+ +  K   ++ G E+D +
Sbjct: 547 PPRTGVKEAVTTLIASGVSIKM----ITGDSQETAVAIASRLGLYSKTSQSVSGEEIDAM 602

Query: 103 E 103
           +
Sbjct: 603 D 603


>gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo
           sapiens]
          Length = 949

 Score = 26.6 bits (57), Expect = 6.1
 Identities = 17/61 (27%), Positives = 28/61 (45%), Gaps = 4/61 (6%)

Query: 43  PEHVGVKVGVRTRGCNGLSYTLEYTKTKGDSDEEVIQDGVRVFIEKKAQLTLLGTEMDYV 102
           P   GVK  V T   +G+S  +      GDS E  +    R+ +  K   ++ G E+D +
Sbjct: 547 PPRTGVKEAVTTLIASGVSIKM----ITGDSQETAVAIASRLGLYSKTSQSVSGEEIDAM 602

Query: 103 E 103
           +
Sbjct: 603 D 603


>gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo
           sapiens]
          Length = 888

 Score = 26.6 bits (57), Expect = 6.1
 Identities = 17/61 (27%), Positives = 28/61 (45%), Gaps = 4/61 (6%)

Query: 43  PEHVGVKVGVRTRGCNGLSYTLEYTKTKGDSDEEVIQDGVRVFIEKKAQLTLLGTEMDYV 102
           P   GVK  V T   +G+S  +      GDS E  +    R+ +  K   ++ G E+D +
Sbjct: 547 PPRTGVKEAVTTLIASGVSIKM----ITGDSQETAVAIASRLGLYSKTSQSVSGEEIDAM 602

Query: 103 E 103
           +
Sbjct: 603 D 603


>gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo
           sapiens]
          Length = 919

 Score = 26.6 bits (57), Expect = 6.1
 Identities = 17/61 (27%), Positives = 28/61 (45%), Gaps = 4/61 (6%)

Query: 43  PEHVGVKVGVRTRGCNGLSYTLEYTKTKGDSDEEVIQDGVRVFIEKKAQLTLLGTEMDYV 102
           P   GVK  V T   +G+S  +      GDS E  +    R+ +  K   ++ G E+D +
Sbjct: 547 PPRTGVKEAVTTLIASGVSIKM----ITGDSQETAVAIASRLGLYSKTSQSVSGEEIDAM 602

Query: 103 E 103
           +
Sbjct: 603 D 603


>gi|4758942 septin 4 isoform 1 [Homo sapiens]
          Length = 478

 Score = 26.6 bits (57), Expect = 6.1
 Identities = 10/25 (40%), Positives = 18/25 (72%)

Query: 26  TLTPSAVNKIKQLLKDKPEHVGVKV 50
           TLTP  V+  K+ ++++ EH G+K+
Sbjct: 293 TLTPPEVDHKKRKIREEIEHFGIKI 317


>gi|17986247 septin 4 isoform 3 [Homo sapiens]
          Length = 459

 Score = 26.6 bits (57), Expect = 6.1
 Identities = 10/25 (40%), Positives = 18/25 (72%)

Query: 26  TLTPSAVNKIKQLLKDKPEHVGVKV 50
           TLTP  V+  K+ ++++ EH G+K+
Sbjct: 274 TLTPPEVDHKKRKIREEIEHFGIKI 298


>gi|76257392 ubiquitin specific protease 48 isoform b [Homo sapiens]
          Length = 485

 Score = 26.2 bits (56), Expect = 8.0
 Identities = 11/38 (28%), Positives = 19/38 (50%)

Query: 95  LGTEMDYVEDKLSSSRKARGSFGAHCRNHVTVTCWKIK 132
           LG E D  E   S +RK +   G HC  +  +  ++++
Sbjct: 384 LGIEEDLAEPSKSQTRKPKCGKGTHCSRNAYMLVYRLQ 421


>gi|52630449 ubiquitin specific protease 48 isoform a [Homo sapiens]
          Length = 1035

 Score = 26.2 bits (56), Expect = 8.0
 Identities = 11/38 (28%), Positives = 19/38 (50%)

Query: 95  LGTEMDYVEDKLSSSRKARGSFGAHCRNHVTVTCWKIK 132
           LG E D  E   S +RK +   G HC  +  +  ++++
Sbjct: 384 LGIEEDLAEPSKSQTRKPKCGKGTHCSRNAYMLVYRLQ 421


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.130    0.368 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,531,608
Number of Sequences: 37866
Number of extensions: 172070
Number of successful extensions: 463
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 453
Number of HSP's gapped (non-prelim): 16
length of query: 132
length of database: 18,247,518
effective HSP length: 91
effective length of query: 41
effective length of database: 14,801,712
effective search space: 606870192
effective search space used: 606870192
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 56 (26.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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