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Search of human proteins with 32189376
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|32189376 thyroid hormone receptor interactor 4 [Homo
sapiens]
(581 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|32189376 thyroid hormone receptor interactor 4 [Homo sapiens] 1181 0.0
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 41 0.003
gi|46852174 kinesin family member 3A [Homo sapiens] 38 0.022
gi|219521893 coiled-coil transcriptional coactivator isoform 2 [... 38 0.022
gi|14149742 coiled-coil transcriptional coactivator isoform 1 [H... 38 0.022
gi|19743801 zinc finger protein 274 isoform c [Homo sapiens] 36 0.085
gi|7706507 zinc finger protein 274 isoform a [Homo sapiens] 36 0.085
gi|19743798 zinc finger protein 274 isoform b [Homo sapiens] 36 0.085
gi|15208660 tripartite motif protein 21 [Homo sapiens] 36 0.11
gi|146262005 CTAGE family, member 6 [Homo sapiens] 35 0.15
gi|115298659 spectrin, alpha, erythrocytic 1 [Homo sapiens] 35 0.19
gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo... 35 0.19
gi|32967603 bromodomain adjacent to zinc finger domain, 1A isofo... 35 0.19
gi|169646749 angiopoietin 2 isoform b precursor [Homo sapiens] 35 0.25
gi|4557315 angiopoietin 2 isoform a precursor [Homo sapiens] 35 0.25
gi|23238244 sorting nexin 16 isoform a [Homo sapiens] 35 0.25
gi|23238246 sorting nexin 16 isoform a [Homo sapiens] 35 0.25
gi|23238248 sorting nexin 16 isoform b [Homo sapiens] 35 0.25
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 34 0.32
gi|197313732 pleckstrin homology-like domain, family B, member 2... 34 0.32
gi|197313730 pleckstrin homology-like domain, family B, member 2... 34 0.32
gi|197313728 pleckstrin homology-like domain, family B, member 2... 34 0.32
gi|21955172 pleckstrin homology-like domain, family B, member 2 ... 34 0.32
gi|222537714 taxilin beta [Homo sapiens] 34 0.42
gi|162951881 tousled-like kinase 2 isoform B [Homo sapiens] 34 0.42
gi|45643117 tousled-like kinase 2 isoform A [Homo sapiens] 34 0.42
gi|112382372 guanylate binding protein 3 [Homo sapiens] 34 0.42
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens] 33 0.55
gi|32967601 ankyrin 3 isoform 1 [Homo sapiens] 33 0.55
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do... 33 0.55
>gi|32189376 thyroid hormone receptor interactor 4 [Homo sapiens]
Length = 581
Score = 1181 bits (3056), Expect = 0.0
Identities = 581/581 (100%), Positives = 581/581 (100%)
Query: 1 MAVAGAVSGEPLVHWCTQQLRKTFGLDVSEEIIQYVLSIESAEEIREYVTDLLQGNEGKK 60
MAVAGAVSGEPLVHWCTQQLRKTFGLDVSEEIIQYVLSIESAEEIREYVTDLLQGNEGKK
Sbjct: 1 MAVAGAVSGEPLVHWCTQQLRKTFGLDVSEEIIQYVLSIESAEEIREYVTDLLQGNEGKK 60
Query: 61 GQFIEELITKWQKNDQELISDPLQQCFKKDEILDGQKSGDHLKRGRKKGRNRQEVPAFTE 120
GQFIEELITKWQKNDQELISDPLQQCFKKDEILDGQKSGDHLKRGRKKGRNRQEVPAFTE
Sbjct: 61 GQFIEELITKWQKNDQELISDPLQQCFKKDEILDGQKSGDHLKRGRKKGRNRQEVPAFTE 120
Query: 121 PDTTAEVKTPFDLAKAQENSNSVKKKTKFVNLYTREGQDRLAVLLPGRHPCDCLGQKHKL 180
PDTTAEVKTPFDLAKAQENSNSVKKKTKFVNLYTREGQDRLAVLLPGRHPCDCLGQKHKL
Sbjct: 121 PDTTAEVKTPFDLAKAQENSNSVKKKTKFVNLYTREGQDRLAVLLPGRHPCDCLGQKHKL 180
Query: 181 INNCLICGRIVCEQEGSGPCLFCGTLVCTHEEQDILQRDSNKSQKLLKKLMSGVENSGKV 240
INNCLICGRIVCEQEGSGPCLFCGTLVCTHEEQDILQRDSNKSQKLLKKLMSGVENSGKV
Sbjct: 181 INNCLICGRIVCEQEGSGPCLFCGTLVCTHEEQDILQRDSNKSQKLLKKLMSGVENSGKV 240
Query: 241 DISTKDLLPHQELRIKSGLEKAIKHKDKLLEFDRTSIRRTQVIDDESDYFASDSNQWLSK 300
DISTKDLLPHQELRIKSGLEKAIKHKDKLLEFDRTSIRRTQVIDDESDYFASDSNQWLSK
Sbjct: 241 DISTKDLLPHQELRIKSGLEKAIKHKDKLLEFDRTSIRRTQVIDDESDYFASDSNQWLSK 300
Query: 301 LERETLQKREEELRELRHASRLSKKVTIDFAGRKILEEENSLAEYHSRLDETIQAIANGT 360
LERETLQKREEELRELRHASRLSKKVTIDFAGRKILEEENSLAEYHSRLDETIQAIANGT
Sbjct: 301 LERETLQKREEELRELRHASRLSKKVTIDFAGRKILEEENSLAEYHSRLDETIQAIANGT 360
Query: 361 LNQPLTKLDRSSEEPLGVLVNPNMYQSPPQWVDHTGAASQKKAFRSSGFGLEFNSFQHQL 420
LNQPLTKLDRSSEEPLGVLVNPNMYQSPPQWVDHTGAASQKKAFRSSGFGLEFNSFQHQL
Sbjct: 361 LNQPLTKLDRSSEEPLGVLVNPNMYQSPPQWVDHTGAASQKKAFRSSGFGLEFNSFQHQL 420
Query: 421 RIQDQEFQEGFDGGWCLSVHQPWASLLVRGIKRVEGRSWYTPHRGRLWIAATAKKPSPQE 480
RIQDQEFQEGFDGGWCLSVHQPWASLLVRGIKRVEGRSWYTPHRGRLWIAATAKKPSPQE
Sbjct: 421 RIQDQEFQEGFDGGWCLSVHQPWASLLVRGIKRVEGRSWYTPHRGRLWIAATAKKPSPQE 480
Query: 481 VSELQATYRLLRGKDVEFPNDYPSGCLLGCVDLIDCLSQKQFKEQFPDISQESDSPFVFI 540
VSELQATYRLLRGKDVEFPNDYPSGCLLGCVDLIDCLSQKQFKEQFPDISQESDSPFVFI
Sbjct: 481 VSELQATYRLLRGKDVEFPNDYPSGCLLGCVDLIDCLSQKQFKEQFPDISQESDSPFVFI 540
Query: 541 CKNPQEMVVKFPIKGNPKIWKLDSKIHQGAKKGLMKQNKAV 581
CKNPQEMVVKFPIKGNPKIWKLDSKIHQGAKKGLMKQNKAV
Sbjct: 541 CKNPQEMVVKFPIKGNPKIWKLDSKIHQGAKKGLMKQNKAV 581
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 40.8 bits (94), Expect = 0.003
Identities = 69/332 (20%), Positives = 129/332 (38%), Gaps = 74/332 (22%)
Query: 27 DVSEEIIQYVLSIESAEEIREYVTDLLQGNEGKKGQFIEELITKWQKNDQELISDPLQQC 86
++ +E + +L+ ES EI E + L + GK Q E + + Q +D + L+
Sbjct: 468 NLQQEKQEAILNYESLREIMEILQTELGESAGKISQEFESM-KQQQASDVHELQQKLRTA 526
Query: 87 F-KKDEILDGQKSGDHLKRGRKKGRNRQE-VPAFTEPDTTAEVKTPFDLAKAQENSNSVK 144
F +KD +L+ + + L+ +K ++QE VP + K L + +K
Sbjct: 527 FTEKDALLE---TVNRLQGENEKLLSQQELVPELENTIKNLQEKNGVYLLSLSQRDTMLK 583
Query: 145 KKTKFVNLYTREGQDRLAVLLPGRHPCDCLGQKHKLINNCLICGRIVCEQEGSGPCLFCG 204
+ +N T E D F
Sbjct: 584 ELEGKINSLTEEKDD------------------------------------------FIN 601
Query: 205 TLVCTHEEQDILQRDSNKSQKLLKKLMSGVENSGKVDISTKDLLPHQELRIKSGLEKAIK 264
L +HEE D + + ++L+ +L VE + I L + + GLE+ +K
Sbjct: 602 KLKNSHEEMDNFHKKCEREERLILELGKKVEQT----IQYNSELEQKVNELTGGLEETLK 657
Query: 265 HKD-------------KLLEFDRTSI-RRTQVIDDESDYFASDSNQWLSKLERETLQKRE 310
KD K+L D+ + + + +E++ +S+ Q LE QK +
Sbjct: 658 EKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQKED 717
Query: 311 EELRELRHASRLSKKVTIDFAGRKILEEENSL 342
L+E H ++L KK+ + ++EE+++L
Sbjct: 718 VILKE--HITQLEKKLQL------MVEEQDNL 741
>gi|46852174 kinesin family member 3A [Homo sapiens]
Length = 699
Score = 38.1 bits (87), Expect = 0.022
Identities = 42/154 (27%), Positives = 67/154 (43%), Gaps = 14/154 (9%)
Query: 211 EEQDILQRDSNKS-QKLLKKLMSGVENSGKVDISTKDLLPHQELRIKSGLEKAIKHK--- 266
+ +D L R K ++L KKL G E SG DIS + +E + EK K +
Sbjct: 354 DPKDALLRQFQKEIEELKKKLEEGEEISGS-DISGSEEDDDEEGEVGEDGEKRKKRRGKK 412
Query: 267 ----DKLLEFDRTSIRRTQVIDDESDYFASDSNQ---WLSKLERETLQKREEELRELRHA 319
DK++E + ++ + D + N+ L K E++ L+ ++E L
Sbjct: 413 KVSPDKMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKL 472
Query: 320 SRLSKKVTIDFAG--RKILEEENSLAEYHSRLDE 351
S L KKV + K E+E L E + L+E
Sbjct: 473 SALEKKVIVGGVDLLAKAEEQEKLLEESNMELEE 506
>gi|219521893 coiled-coil transcriptional coactivator isoform 2
[Homo sapiens]
Length = 606
Score = 38.1 bits (87), Expect = 0.022
Identities = 30/124 (24%), Positives = 62/124 (50%), Gaps = 16/124 (12%)
Query: 256 KSGLEKAIK-HKDKLLEFDRTSIRRTQVIDDESDYFASDSNQWLSKLERET------LQK 308
++GL ++++ KDK+L+ +R + + +E + + + ++L RE L +
Sbjct: 327 RAGLLQSVEAEKDKILKLSAEILRLEKAVQEER----TQNQVFKTELAREKDSSLVQLSE 382
Query: 309 REEELRELRHASRLSKKVTIDFAGRKILEEENSLAEYHSRLDETIQAIANGTLNQPLTKL 368
+ EL ELR A R+ +K ++ EE+ L EY +L+ ++ +A+ N+ T
Sbjct: 383 SKRELTELRSALRVLQKEK-----EQLQEEKQELLEYMRKLEARLEKVADEKWNEDATTE 437
Query: 369 DRSS 372
D +
Sbjct: 438 DEEA 441
>gi|14149742 coiled-coil transcriptional coactivator isoform 1 [Homo
sapiens]
Length = 691
Score = 38.1 bits (87), Expect = 0.022
Identities = 30/124 (24%), Positives = 62/124 (50%), Gaps = 16/124 (12%)
Query: 256 KSGLEKAIK-HKDKLLEFDRTSIRRTQVIDDESDYFASDSNQWLSKLERET------LQK 308
++GL ++++ KDK+L+ +R + + +E + + + ++L RE L +
Sbjct: 412 RAGLLQSVEAEKDKILKLSAEILRLEKAVQEER----TQNQVFKTELAREKDSSLVQLSE 467
Query: 309 REEELRELRHASRLSKKVTIDFAGRKILEEENSLAEYHSRLDETIQAIANGTLNQPLTKL 368
+ EL ELR A R+ +K ++ EE+ L EY +L+ ++ +A+ N+ T
Sbjct: 468 SKRELTELRSALRVLQKEK-----EQLQEEKQELLEYMRKLEARLEKVADEKWNEDATTE 522
Query: 369 DRSS 372
D +
Sbjct: 523 DEEA 526
>gi|19743801 zinc finger protein 274 isoform c [Homo sapiens]
Length = 653
Score = 36.2 bits (82), Expect = 0.085
Identities = 41/165 (24%), Positives = 77/165 (46%), Gaps = 23/165 (13%)
Query: 194 QEGSGPCLFCGTLVCTHEEQDILQRDSNKSQKLLKKLMSGVENSGKVDISTKDLLPHQEL 253
QE S C TL +D LQ + Q + K M E++ + D+ K ++E
Sbjct: 355 QESSRDCALSSTL------EDTLQGGVQEVQDTVLKQM---ESAQEKDLPQKKHFDNRES 405
Query: 254 RIKSGLEKAIKHKDKLLEFDRTSIRRTQVIDDESDYFASDSNQ-WLSKLE-RETLQKREE 311
+ SG L+ ++ S+++ + +++ A D+NQ L K+ R+ L+KR+
Sbjct: 406 QANSGA----------LDTNQVSLQKIDNPESQANSGALDTNQVLLHKIPPRKRLRKRDS 455
Query: 312 ELRELRHASRLSKKVTIDFAGRKILEEENSLAEYHSRLDETIQAI 356
+++ ++H SR+ K+ R+ +E N + SR + I I
Sbjct: 456 QVKSMKHNSRV--KIHQKSCERQKAKEGNGCRKTFSRSTKQITFI 498
>gi|7706507 zinc finger protein 274 isoform a [Homo sapiens]
Length = 621
Score = 36.2 bits (82), Expect = 0.085
Identities = 41/165 (24%), Positives = 77/165 (46%), Gaps = 23/165 (13%)
Query: 194 QEGSGPCLFCGTLVCTHEEQDILQRDSNKSQKLLKKLMSGVENSGKVDISTKDLLPHQEL 253
QE S C TL +D LQ + Q + K M E++ + D+ K ++E
Sbjct: 323 QESSRDCALSSTL------EDTLQGGVQEVQDTVLKQM---ESAQEKDLPQKKHFDNRES 373
Query: 254 RIKSGLEKAIKHKDKLLEFDRTSIRRTQVIDDESDYFASDSNQ-WLSKLE-RETLQKREE 311
+ SG L+ ++ S+++ + +++ A D+NQ L K+ R+ L+KR+
Sbjct: 374 QANSGA----------LDTNQVSLQKIDNPESQANSGALDTNQVLLHKIPPRKRLRKRDS 423
Query: 312 ELRELRHASRLSKKVTIDFAGRKILEEENSLAEYHSRLDETIQAI 356
+++ ++H SR+ K+ R+ +E N + SR + I I
Sbjct: 424 QVKSMKHNSRV--KIHQKSCERQKAKEGNGCRKTFSRSTKQITFI 466
>gi|19743798 zinc finger protein 274 isoform b [Homo sapiens]
Length = 548
Score = 36.2 bits (82), Expect = 0.085
Identities = 41/165 (24%), Positives = 77/165 (46%), Gaps = 23/165 (13%)
Query: 194 QEGSGPCLFCGTLVCTHEEQDILQRDSNKSQKLLKKLMSGVENSGKVDISTKDLLPHQEL 253
QE S C TL +D LQ + Q + K M E++ + D+ K ++E
Sbjct: 250 QESSRDCALSSTL------EDTLQGGVQEVQDTVLKQM---ESAQEKDLPQKKHFDNRES 300
Query: 254 RIKSGLEKAIKHKDKLLEFDRTSIRRTQVIDDESDYFASDSNQ-WLSKLE-RETLQKREE 311
+ SG L+ ++ S+++ + +++ A D+NQ L K+ R+ L+KR+
Sbjct: 301 QANSGA----------LDTNQVSLQKIDNPESQANSGALDTNQVLLHKIPPRKRLRKRDS 350
Query: 312 ELRELRHASRLSKKVTIDFAGRKILEEENSLAEYHSRLDETIQAI 356
+++ ++H SR+ K+ R+ +E N + SR + I I
Sbjct: 351 QVKSMKHNSRV--KIHQKSCERQKAKEGNGCRKTFSRSTKQITFI 393
>gi|15208660 tripartite motif protein 21 [Homo sapiens]
Length = 475
Score = 35.8 bits (81), Expect = 0.11
Identities = 40/184 (21%), Positives = 73/184 (39%), Gaps = 32/184 (17%)
Query: 190 IVCEQEGSGPCLFCGTLVCTHEEQDILQRDSNKSQKLLKKLMSGVENSGKVDISTKDLLP 249
+ CE++G C C Q ++ ++ + E K+ ++ +L
Sbjct: 101 LFCEKDGKALCWVCA------------QSRKHRDHAMVPLEEAAQEYQEKLQVALGELRR 148
Query: 250 HQELRIKSGLEKAIKHKD--KLLEFDRTSIRRTQVIDDESDYFASDSNQWLSKLERETLQ 307
QEL K +E AIK D K +E ++ I V + ++ + + L +LE++
Sbjct: 149 KQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFV--QQKNFLVEEEQRQLQELEKD--- 203
Query: 308 KREEELRELRHASRLSKKVTIDFAGRKILEEENSLAEYHSRLDETIQAIANGTLNQPLTK 367
E+LR L K+ ++ +L E S LD + A L + +
Sbjct: 204 -EREQLRILGEKE------------AKLAQQSQALQELISELDRRCHSSALELLQEVIIV 250
Query: 368 LDRS 371
L+RS
Sbjct: 251 LERS 254
>gi|146262005 CTAGE family, member 6 [Homo sapiens]
Length = 777
Score = 35.4 bits (80), Expect = 0.15
Identities = 37/150 (24%), Positives = 72/150 (48%), Gaps = 20/150 (13%)
Query: 227 LKKLMSGVENSGKVDISTKDLLPHQELRIKSGLEKAIKHKDKLLEFDRTSIRRTQVIDDE 286
LKKL+ ++ K+++S K L + I L + K K++L E + + + + E
Sbjct: 315 LKKLI----HAAKLNVSLKSLEGERN-HIIIQLSEVDKTKEELTEHIKNLQTQQESLQSE 369
Query: 287 SDYFASDSNQWLSKLERETLQKREEELRELRHASRLSKKVTIDFAGRKILEEENSLAEYH 346
+ YF S++ + KL+ T +E+E+ +L +K+T++ R +EEE L++
Sbjct: 370 NIYFESENQKLQQKLKIMTEFYQEDEM-------KLYRKLTVEENYR--IEEEEKLSKVE 420
Query: 347 SRLDETIQAIANGTLNQPLTKLDRSSEEPL 376
+L + + + KL + EE L
Sbjct: 421 EKLSRATEQL------ETYRKLAKDLEEEL 444
>gi|115298659 spectrin, alpha, erythrocytic 1 [Homo sapiens]
Length = 2419
Score = 35.0 bits (79), Expect = 0.19
Identities = 36/131 (27%), Positives = 63/131 (48%), Gaps = 11/131 (8%)
Query: 252 ELRIKSGLEKAIKHKDKLLEFDRTSIRRTQVIDDESDYFAS--DSNQWLSKLERETLQKR 309
E +K LE+ +H D LLE ++ + + S D WLS E ETL
Sbjct: 1575 EEAMKEQLEQLKEHWDHLLERTNDKGKKLNEASRQQRFNTSIRDFEFWLS--EAETLLAM 1632
Query: 310 EEELRELRHASRLSKKVTIDFAGRKILEEENSLAEYHSRLDETIQAIANGTLN--QPLTK 367
+++ R+L A L KK + R++L E++L + ++ ++ +++GT N Q + K
Sbjct: 1633 KDQARDLASAGNLLKKHQL--LEREMLAREDALKDLNTLAED---LLSSGTFNVDQIVKK 1687
Query: 368 LDRSSEEPLGV 378
D ++ L V
Sbjct: 1688 KDNVNKRFLNV 1698
>gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform
b [Homo sapiens]
Length = 1524
Score = 35.0 bits (79), Expect = 0.19
Identities = 30/117 (25%), Positives = 56/117 (47%), Gaps = 17/117 (14%)
Query: 239 KVDISTKDLLPHQELRIKSGLEKAIKHKDKLL---EFDRTSIRRTQVIDDESDYFASDSN 295
++ IS +D + +++ + S KA K +DKLL E + + ++ +++D +
Sbjct: 282 RIHISQEDNVANKQT-LASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEA--- 337
Query: 296 QWLSKLERETLQKREEELRELRHASRLSK-------KVTIDFAGRKILEEENSLAEY 345
K E+E +K+ EEL+++ RL K KV + K+ EE+ EY
Sbjct: 338 ---KKKEKEDKEKKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKRKYVEY 391
>gi|32967603 bromodomain adjacent to zinc finger domain, 1A isoform
a [Homo sapiens]
Length = 1556
Score = 35.0 bits (79), Expect = 0.19
Identities = 30/117 (25%), Positives = 56/117 (47%), Gaps = 17/117 (14%)
Query: 239 KVDISTKDLLPHQELRIKSGLEKAIKHKDKLL---EFDRTSIRRTQVIDDESDYFASDSN 295
++ IS +D + +++ + S KA K +DKLL E + + ++ +++D +
Sbjct: 282 RIHISQEDNVANKQT-LASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEA--- 337
Query: 296 QWLSKLERETLQKREEELRELRHASRLSK-------KVTIDFAGRKILEEENSLAEY 345
K E+E +K+ EEL+++ RL K KV + K+ EE+ EY
Sbjct: 338 ---KKKEKEDKEKKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKRKYVEY 391
>gi|169646749 angiopoietin 2 isoform b precursor [Homo sapiens]
Length = 495
Score = 34.7 bits (78), Expect = 0.25
Identities = 27/106 (25%), Positives = 50/106 (47%), Gaps = 8/106 (7%)
Query: 266 KDKLLEFDRTSIRRTQVIDDESDYFASDSNQWLSKLERETLQKREEELRELRHASRLSKK 325
+D LE+D S++R QV+++ ++ QWL KLE ++E+ E++ + ++
Sbjct: 67 RDAPLEYD-DSVQRLQVLEN----IMENNTQWLMKLENYIQDNMKKEMVEIQQNAVQNQT 121
Query: 326 VTIDFAGRKILEEENSLAEYHSRLDETIQAIANGTLNQPLTKLDRS 371
+ G +L N AE +L + + N T L L+ S
Sbjct: 122 AVMIEIGTNLL---NQTAEQTRKLTDVEAQVLNQTTRLELQLLEHS 164
>gi|4557315 angiopoietin 2 isoform a precursor [Homo sapiens]
Length = 496
Score = 34.7 bits (78), Expect = 0.25
Identities = 27/106 (25%), Positives = 50/106 (47%), Gaps = 8/106 (7%)
Query: 266 KDKLLEFDRTSIRRTQVIDDESDYFASDSNQWLSKLERETLQKREEELRELRHASRLSKK 325
+D LE+D S++R QV+++ ++ QWL KLE ++E+ E++ + ++
Sbjct: 67 RDAPLEYD-DSVQRLQVLEN----IMENNTQWLMKLENYIQDNMKKEMVEIQQNAVQNQT 121
Query: 326 VTIDFAGRKILEEENSLAEYHSRLDETIQAIANGTLNQPLTKLDRS 371
+ G +L N AE +L + + N T L L+ S
Sbjct: 122 AVMIEIGTNLL---NQTAEQTRKLTDVEAQVLNQTTRLELQLLEHS 164
>gi|23238244 sorting nexin 16 isoform a [Homo sapiens]
Length = 344
Score = 34.7 bits (78), Expect = 0.25
Identities = 41/140 (29%), Positives = 60/140 (42%), Gaps = 24/140 (17%)
Query: 178 HKLINNCLICGRIVCEQEGSGPC-------LFCGTLVCTHEEQDILQRDSNKSQKLLKKL 230
HK I NCL +C + GP FC TL T+ + K + LKKL
Sbjct: 198 HKDIANCLAVREFLCLDDPPGPFDSLEESRAFCETLEETNYRLQKELLEKQKEMESLKKL 257
Query: 231 MSGVENSGKVD-----ISTKDLLPHQELRI-KSGLEKAIKHKDKLLEFDRTSIRRTQVID 284
+S E +D I T L P + L + ++ E+ +K + LE D+ V+D
Sbjct: 258 LS--EKQLHIDTLENRIRTLSLEPEESLDVSETEGEQILKVESSALEVDQ------DVLD 309
Query: 285 DESDYFASDSNQWLSKLERE 304
+ES +D+ LS E E
Sbjct: 310 EES---RADNKPCLSFSEPE 326
>gi|23238246 sorting nexin 16 isoform a [Homo sapiens]
Length = 344
Score = 34.7 bits (78), Expect = 0.25
Identities = 41/140 (29%), Positives = 60/140 (42%), Gaps = 24/140 (17%)
Query: 178 HKLINNCLICGRIVCEQEGSGPC-------LFCGTLVCTHEEQDILQRDSNKSQKLLKKL 230
HK I NCL +C + GP FC TL T+ + K + LKKL
Sbjct: 198 HKDIANCLAVREFLCLDDPPGPFDSLEESRAFCETLEETNYRLQKELLEKQKEMESLKKL 257
Query: 231 MSGVENSGKVD-----ISTKDLLPHQELRI-KSGLEKAIKHKDKLLEFDRTSIRRTQVID 284
+S E +D I T L P + L + ++ E+ +K + LE D+ V+D
Sbjct: 258 LS--EKQLHIDTLENRIRTLSLEPEESLDVSETEGEQILKVESSALEVDQ------DVLD 309
Query: 285 DESDYFASDSNQWLSKLERE 304
+ES +D+ LS E E
Sbjct: 310 EES---RADNKPCLSFSEPE 326
>gi|23238248 sorting nexin 16 isoform b [Homo sapiens]
Length = 315
Score = 34.7 bits (78), Expect = 0.25
Identities = 41/140 (29%), Positives = 60/140 (42%), Gaps = 24/140 (17%)
Query: 178 HKLINNCLICGRIVCEQEGSGPC-------LFCGTLVCTHEEQDILQRDSNKSQKLLKKL 230
HK I NCL +C + GP FC TL T+ + K + LKKL
Sbjct: 169 HKDIANCLAVREFLCLDDPPGPFDSLEESRAFCETLEETNYRLQKELLEKQKEMESLKKL 228
Query: 231 MSGVENSGKVD-----ISTKDLLPHQELRI-KSGLEKAIKHKDKLLEFDRTSIRRTQVID 284
+S E +D I T L P + L + ++ E+ +K + LE D+ V+D
Sbjct: 229 LS--EKQLHIDTLENRIRTLSLEPEESLDVSETEGEQILKVESSALEVDQ------DVLD 280
Query: 285 DESDYFASDSNQWLSKLERE 304
+ES +D+ LS E E
Sbjct: 281 EES---RADNKPCLSFSEPE 297
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 34.3 bits (77), Expect = 0.32
Identities = 59/246 (23%), Positives = 99/246 (40%), Gaps = 43/246 (17%)
Query: 141 NSVKKKTKFVNLYTREGQDRLAVLLPGRHPCDCLGQKHKLINNCLICGRIVCEQEGSGPC 200
N+++ K N++ D L C L QK K +++CL+ + V E
Sbjct: 1823 NNIQAKQNLENVF----DDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEME--- 1875
Query: 201 LFCGTLVCTHEEQDILQR--DSNKSQKLLKKLMSGVENSGKVDISTKDLLPHQELR---I 255
L +E+ LQ+ NK +LL++ E K + LL + E + +
Sbjct: 1876 ----ELTSKYEKLQALQQMDGRNKPTELLEE---NTEEKSKSHLVQPKLLSNMEAQHNDL 1928
Query: 256 KSGLEKAIKHKDKL------LEFDRTSIRRTQVIDDESDYFASDSNQWLSKLERETLQKR 309
+ L A + K KL L+ D +R+ E + + +Q ERE K+
Sbjct: 1929 EFKLAGAEREKQKLGKEIVRLQKDLRMLRKEH--QQELEILKKEYDQ-----EREEKIKQ 1981
Query: 310 EEELRELRHASRLSKKVTIDFAGRKILEEENS-LAEYHSRLDETIQAIANGTLNQPLTKL 368
E+E EL+H S L ++++ E N+ LA+ L+ TI+ N L
Sbjct: 1982 EQEDLELKHNSTL----------KQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELL 2031
Query: 369 DRSSEE 374
+ EE
Sbjct: 2032 ESHQEE 2037
>gi|197313732 pleckstrin homology-like domain, family B, member 2
isoform a [Homo sapiens]
Length = 1253
Score = 34.3 bits (77), Expect = 0.32
Identities = 35/182 (19%), Positives = 67/182 (36%), Gaps = 20/182 (10%)
Query: 234 VENSGKVDISTKDLLPHQELRIKSGLEKAIKHKDKLLEFDRTSIRRTQVIDDESDYFASD 293
+E+ ++D ++L + + K+K+ + + Q E D+F +
Sbjct: 730 LEHESRLDEEKENLTQQLLREVAEYQRNIVSRKEKISALKKQANHIVQQAQREQDHFVKE 789
Query: 294 SNQWLSKLERETLQKREEELRELRHASRLSKKVTIDFAGRKILEEENSLAEYHSRLDETI 353
N + L+RE + L KK + G+ N+L E + ++E
Sbjct: 790 KNNLIMMLQREK-----------ENLCNLEKKYSSLSGGKGFPVNPNTLKEGYISVNEIN 838
Query: 354 QAIANGTLNQPLTKL----DRSSEEPLGVLVNPNMYQSPPQWVDHTGAASQKKAFRSSGF 409
+ N T P T+ D + EP ++ S PQ +H + ++K G
Sbjct: 839 EPCGNSTNLSPSTQFPADADAVATEPATAVL-----ASQPQSKEHFRSLEERKKQHKEGL 893
Query: 410 GL 411
L
Sbjct: 894 YL 895
>gi|197313730 pleckstrin homology-like domain, family B, member 2
isoform a [Homo sapiens]
Length = 1253
Score = 34.3 bits (77), Expect = 0.32
Identities = 35/182 (19%), Positives = 67/182 (36%), Gaps = 20/182 (10%)
Query: 234 VENSGKVDISTKDLLPHQELRIKSGLEKAIKHKDKLLEFDRTSIRRTQVIDDESDYFASD 293
+E+ ++D ++L + + K+K+ + + Q E D+F +
Sbjct: 730 LEHESRLDEEKENLTQQLLREVAEYQRNIVSRKEKISALKKQANHIVQQAQREQDHFVKE 789
Query: 294 SNQWLSKLERETLQKREEELRELRHASRLSKKVTIDFAGRKILEEENSLAEYHSRLDETI 353
N + L+RE + L KK + G+ N+L E + ++E
Sbjct: 790 KNNLIMMLQREK-----------ENLCNLEKKYSSLSGGKGFPVNPNTLKEGYISVNEIN 838
Query: 354 QAIANGTLNQPLTKL----DRSSEEPLGVLVNPNMYQSPPQWVDHTGAASQKKAFRSSGF 409
+ N T P T+ D + EP ++ S PQ +H + ++K G
Sbjct: 839 EPCGNSTNLSPSTQFPADADAVATEPATAVL-----ASQPQSKEHFRSLEERKKQHKEGL 893
Query: 410 GL 411
L
Sbjct: 894 YL 895
>gi|197313728 pleckstrin homology-like domain, family B, member 2
isoform b [Homo sapiens]
Length = 1237
Score = 34.3 bits (77), Expect = 0.32
Identities = 35/182 (19%), Positives = 67/182 (36%), Gaps = 20/182 (10%)
Query: 234 VENSGKVDISTKDLLPHQELRIKSGLEKAIKHKDKLLEFDRTSIRRTQVIDDESDYFASD 293
+E+ ++D ++L + + K+K+ + + Q E D+F +
Sbjct: 714 LEHESRLDEEKENLTQQLLREVAEYQRNIVSRKEKISALKKQANHIVQQAQREQDHFVKE 773
Query: 294 SNQWLSKLERETLQKREEELRELRHASRLSKKVTIDFAGRKILEEENSLAEYHSRLDETI 353
N + L+RE + L KK + G+ N+L E + ++E
Sbjct: 774 KNNLIMMLQREK-----------ENLCNLEKKYSSLSGGKGFPVNPNTLKEGYISVNEIN 822
Query: 354 QAIANGTLNQPLTKL----DRSSEEPLGVLVNPNMYQSPPQWVDHTGAASQKKAFRSSGF 409
+ N T P T+ D + EP ++ S PQ +H + ++K G
Sbjct: 823 EPCGNSTNLSPSTQFPADADAVATEPATAVL-----ASQPQSKEHFRSLEERKKQHKEGL 877
Query: 410 GL 411
L
Sbjct: 878 YL 879
>gi|21955172 pleckstrin homology-like domain, family B, member 2
isoform c [Homo sapiens]
Length = 1210
Score = 34.3 bits (77), Expect = 0.32
Identities = 35/182 (19%), Positives = 67/182 (36%), Gaps = 20/182 (10%)
Query: 234 VENSGKVDISTKDLLPHQELRIKSGLEKAIKHKDKLLEFDRTSIRRTQVIDDESDYFASD 293
+E+ ++D ++L + + K+K+ + + Q E D+F +
Sbjct: 687 LEHESRLDEEKENLTQQLLREVAEYQRNIVSRKEKISALKKQANHIVQQAQREQDHFVKE 746
Query: 294 SNQWLSKLERETLQKREEELRELRHASRLSKKVTIDFAGRKILEEENSLAEYHSRLDETI 353
N + L+RE + L KK + G+ N+L E + ++E
Sbjct: 747 KNNLIMMLQREK-----------ENLCNLEKKYSSLSGGKGFPVNPNTLKEGYISVNEIN 795
Query: 354 QAIANGTLNQPLTKL----DRSSEEPLGVLVNPNMYQSPPQWVDHTGAASQKKAFRSSGF 409
+ N T P T+ D + EP ++ S PQ +H + ++K G
Sbjct: 796 EPCGNSTNLSPSTQFPADADAVATEPATAVL-----ASQPQSKEHFRSLEERKKQHKEGL 850
Query: 410 GL 411
L
Sbjct: 851 YL 852
>gi|222537714 taxilin beta [Homo sapiens]
Length = 684
Score = 33.9 bits (76), Expect = 0.42
Identities = 34/152 (22%), Positives = 64/152 (42%), Gaps = 10/152 (6%)
Query: 207 VCTHEEQDILQRDSNKSQKLLKKLMSGVENSGKVDISTKDLLPHQELRIKSGLEKAIKHK 266
V + E + + SNK QKL KK++ G+ + + + L E + + K
Sbjct: 114 VASGEPPTVKEPVSNKEQKLEKKILKGLGKEANLLMQNLNKLQTPEEK----FDFLFKKY 169
Query: 267 DKLLEFDRTSIRRTQVIDDESDYFASDSNQWLSKLERETL--QKREEELRELRHASRLSK 324
+LL+ RT ++ +++ + + +Q + R L K E REL+ ++ K
Sbjct: 170 AELLDEHRTEQKKLKLLQKKQVQIQKEKDQLQGEHSRAILARSKLESLCRELQRHNKTLK 229
Query: 325 KVTIDFAGRKILEEENSLAEYHSRLDETIQAI 356
+ + ++ EEE E S T+ I
Sbjct: 230 EEAL----QRAREEEEKRKEITSHFQSTLTDI 257
>gi|162951881 tousled-like kinase 2 isoform B [Homo sapiens]
Length = 718
Score = 33.9 bits (76), Expect = 0.42
Identities = 31/174 (17%), Positives = 72/174 (41%), Gaps = 3/174 (1%)
Query: 186 ICGRIVCEQEGSGPCLFCGTLV--CTHEEQDILQRDSNKSQKLLKKLMSGVENSGKVDIS 243
+C V Q+ S G C+ ++Q +Q +S ++K+ S +ENS D+
Sbjct: 139 LCFTFVSAQQNSPSSTGSGNTEHSCSSQKQISIQHRQTQSDLTIEKI-SALENSKNSDLE 197
Query: 244 TKDLLPHQELRIKSGLEKAIKHKDKLLEFDRTSIRRTQVIDDESDYFASDSNQWLSKLER 303
K+ LR L + I + K+LE + + R + + S + + +
Sbjct: 198 KKEGRIDDLLRANCDLRRQIDEQQKMLEKYKERLNRCVTMSKKLLIEKSKQEKMACRDKS 257
Query: 304 ETLQKREEELRELRHASRLSKKVTIDFAGRKILEEENSLAEYHSRLDETIQAIA 357
+ R +RH + +++ T +A + +++++ + ++ + +A
Sbjct: 258 MQDRLRLGHFTTVRHGASFTEQWTDGYAFQNLIKQQERINSQREEIERQRKMLA 311
>gi|45643117 tousled-like kinase 2 isoform A [Homo sapiens]
Length = 750
Score = 33.9 bits (76), Expect = 0.42
Identities = 31/174 (17%), Positives = 72/174 (41%), Gaps = 3/174 (1%)
Query: 186 ICGRIVCEQEGSGPCLFCGTLV--CTHEEQDILQRDSNKSQKLLKKLMSGVENSGKVDIS 243
+C V Q+ S G C+ ++Q +Q +S ++K+ S +ENS D+
Sbjct: 171 LCFTFVSAQQNSPSSTGSGNTEHSCSSQKQISIQHRQTQSDLTIEKI-SALENSKNSDLE 229
Query: 244 TKDLLPHQELRIKSGLEKAIKHKDKLLEFDRTSIRRTQVIDDESDYFASDSNQWLSKLER 303
K+ LR L + I + K+LE + + R + + S + + +
Sbjct: 230 KKEGRIDDLLRANCDLRRQIDEQQKMLEKYKERLNRCVTMSKKLLIEKSKQEKMACRDKS 289
Query: 304 ETLQKREEELRELRHASRLSKKVTIDFAGRKILEEENSLAEYHSRLDETIQAIA 357
+ R +RH + +++ T +A + +++++ + ++ + +A
Sbjct: 290 MQDRLRLGHFTTVRHGASFTEQWTDGYAFQNLIKQQERINSQREEIERQRKMLA 343
>gi|112382372 guanylate binding protein 3 [Homo sapiens]
Length = 595
Score = 33.9 bits (76), Expect = 0.42
Identities = 27/131 (20%), Positives = 57/131 (43%), Gaps = 2/131 (1%)
Query: 198 GPCLFCGTLVCTHEEQDILQRDSNKSQKLLKKLMSGVENSGKVDISTKDLLPHQELRIKS 257
G CLF L ++ R +++++L+ + E+ + T +L +E I+
Sbjct: 430 GYCLFIQKLQDLEKKYYEEPRKGIQAEEILQTYLKSKESVTDAILQTDQILTEKEKEIEV 489
Query: 258 GLEKAIKHKDKLLEFDRTSIRRTQVIDDESDYFASDSNQWLSKLERETLQKREEELRELR 317
KA + + I+ Q+++++ + Q K+ERE Q EE+ + L
Sbjct: 490 ECVKAESAQASAKMVEEMQIKYQQMMEEKEKSYQEHVKQLTEKMERERAQLLEEQEKTL- 548
Query: 318 HASRLSKKVTI 328
S+L ++ +
Sbjct: 549 -TSKLQEQARV 558
>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
Length = 1233
Score = 33.5 bits (75), Expect = 0.55
Identities = 40/165 (24%), Positives = 71/165 (43%), Gaps = 19/165 (11%)
Query: 211 EEQDILQRDSNKSQKLLKKLMSGVENSGKVDISTKDLLPHQELRIKSGLEKAIKHKDKLL 270
+ D ++ + + +K L K+M + K +I KD +Q+ ++ HK K L
Sbjct: 254 KRMDKVEDELKEKKKELGKMMREQQQIEK-EIKEKDSELNQKRPQYIKAKENTSHKIKKL 312
Query: 271 EFDRTSIRRTQVIDDESDYFASDSNQWLSKLERETL--QKREEELRELRHASRLSKKVTI 328
E + S++ Q ++ + +LE+E L +K +E E S+
Sbjct: 313 EAAKKSLQNAQ------KHYKKRKGD-MDELEKEMLSVEKARQEFEERMEEESQSQ---- 361
Query: 329 DFAGRKILEEENSLAEYHSRLDETIQAIANGTLNQPLTKLDRSSE 373
GR + EEN + +YH +E + A TL Q L K +R +
Sbjct: 362 ---GRDLTLEENQVKKYHRLKEEASKRAA--TLAQELEKFNRDQK 401
>gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]
Length = 4377
Score = 33.5 bits (75), Expect = 0.55
Identities = 40/178 (22%), Positives = 80/178 (44%), Gaps = 24/178 (13%)
Query: 211 EEQDILQRDSNKSQKLLKKLMSGVENSGKVDISTKDLLPHQELRIKSGLEKAIKHKDKL- 269
E +++ R++ K + K++ ++ + DI+ KD LP + E+ + +++L
Sbjct: 2341 EPTEVIIRETKKHPE--KEMYVYQKDLSRGDINLKDFLPEKHDAFPCSEEQGQQEEEELT 2398
Query: 270 --------LEFDRTSIRRTQVIDDE---SDYFASDSNQWLSKLERETLQKREEELRELRH 318
LE R + +Q D + + DS + L L + +++ ++EL ELR
Sbjct: 2399 AEESLPSYLESSRVNTPVSQEEDSRPSSAQLISDDSYKTLKLLSQHSIEYHDDELSELRG 2458
Query: 319 ASRLSKKVTIDFAGRKILEEENSLAEYHSRLDETIQAIANGTLNQPLTKLDRSSEEPL 376
S FA + +L E+ ++ HS +E++ A G + L D+ S E +
Sbjct: 2459 ES-------YRFAEKMLLSEKLDVS--HSDTEESVTDHA-GPPSSELQGSDKRSREKI 2506
>gi|190341068 forkhead-associated (FHA) phosphopeptide binding
domain 1 [Homo sapiens]
Length = 1412
Score = 33.5 bits (75), Expect = 0.55
Identities = 36/146 (24%), Positives = 68/146 (46%), Gaps = 5/146 (3%)
Query: 201 LFCGTLVCTHEEQDILQRDSNKSQKLLKKLMSGVENSGKVDISTKDLLPHQELRIKSGLE 260
+ C TL + E L+ + ++ K + SG+ +S + DI KD Q S L+
Sbjct: 316 VLCQTLSERNSEITSLKNEG-ENLKRDNAITSGMVSSLQKDILAKDEQVQQLKEEVSHLK 374
Query: 261 KAIKHKDKLLEF--DRTSIRRTQVIDDESDYFASDSNQWLSKLERETLQKREEELRELRH 318
K KD LE R S+ + ++ +++ ++ + KL + +Q E+E+++LR
Sbjct: 375 SQNKDKDHQLEALGSRCSVLKEELKQEDAHRELREAQEKELKLCKTQIQDMEKEMKKLR- 433
Query: 319 ASRLSKKVTIDFAGRKILEEENSLAE 344
+ L K T + L E++ + E
Sbjct: 434 -AELRKSCTEQSVISRTLREKSKVEE 458
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,815,534
Number of Sequences: 37866
Number of extensions: 1086433
Number of successful extensions: 3608
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 101
Number of HSP's that attempted gapping in prelim test: 3544
Number of HSP's gapped (non-prelim): 171
length of query: 581
length of database: 18,247,518
effective HSP length: 108
effective length of query: 473
effective length of database: 14,157,990
effective search space: 6696729270
effective search space used: 6696729270
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.