Guide to the Human Genome
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Search of human proteins with 31657114

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31657114 armadillo repeat containing 4 [Homo sapiens]
         (1044 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31657114 armadillo repeat containing 4 [Homo sapiens]             2065   0.0  
gi|239744025 PREDICTED: hypothetical protein XP_002343006 [Homo ...   303   4e-82
gi|239749766 PREDICTED: similar to armadillo repeat containing 4...   300   6e-81
gi|239755234 PREDICTED: similar to armadillo repeat containing 4...   299   1e-80
gi|189409124 armadillo repeat containing 3 [Homo sapiens]              88   5e-17
gi|91206450 ankyrin and armadillo repeat containing [Homo sapiens]     86   1e-16
gi|4504811 junction plakoglobin [Homo sapiens]                         77   1e-13
gi|12056468 junction plakoglobin [Homo sapiens]                        77   1e-13
gi|148227672 catenin (cadherin-associated protein), beta 1, 88kD...    72   2e-12
gi|148233338 catenin (cadherin-associated protein), beta 1, 88kD...    72   2e-12
gi|4503131 catenin (cadherin-associated protein), beta 1, 88kDa ...    72   2e-12
gi|11034811 catenin (cadherin-associated protein), delta 2 (neur...    58   5e-08
gi|4504897 karyopherin alpha 2 [Homo sapiens]                          56   2e-07
gi|4502247 armadillo repeat protein [Homo sapiens]                     54   1e-06
gi|146231975 catenin, delta 1 isoform 3A [Homo sapiens]                52   3e-06
gi|146231948 catenin, delta 1 isoform 3A [Homo sapiens]                52   3e-06
gi|146231994 catenin, delta 1 isoform 3A [Homo sapiens]                52   3e-06
gi|146231946 catenin, delta 1 isoform 3B [Homo sapiens]                52   3e-06
gi|146231991 catenin, delta 1 isoform 3AB [Homo sapiens]               52   3e-06
gi|146231942 catenin, delta 1 isoform 1A [Homo sapiens]                52   3e-06
gi|146231968 catenin, delta 1 isoform 1A [Homo sapiens]                52   3e-06
gi|146231938 catenin, delta 1 isoform 1A [Homo sapiens]                52   3e-06
gi|10835010 catenin, delta 1 isoform 1B [Homo sapiens]                 52   3e-06
gi|146231962 catenin, delta 1 isoform 1AB [Homo sapiens]               52   3e-06
gi|53829376 plakophilin 4 isoform b [Homo sapiens]                     50   1e-05
gi|53829374 plakophilin 4 isoform a [Homo sapiens]                     50   1e-05
gi|6912678 sperm associated antigen 6 isoform 1 [Homo sapiens]         49   2e-05
gi|27262641 sperm associated antigen 6 isoform 2 [Homo sapiens]        49   2e-05
gi|39812229 karyopherin alpha 5 [Homo sapiens]                         49   2e-05
gi|28875784 armadillo repeat containing 5 isoform b [Homo sapiens]     48   6e-05

>gi|31657114 armadillo repeat containing 4 [Homo sapiens]
          Length = 1044

 Score = 2065 bits (5349), Expect = 0.0
 Identities = 1044/1044 (100%), Positives = 1044/1044 (100%)

Query: 1    MGVALRKLTQWTAAGHGTGILEITPLNEAILKEIIVFVESFIYKHPQEAKFVFVEPLEWN 60
            MGVALRKLTQWTAAGHGTGILEITPLNEAILKEIIVFVESFIYKHPQEAKFVFVEPLEWN
Sbjct: 1    MGVALRKLTQWTAAGHGTGILEITPLNEAILKEIIVFVESFIYKHPQEAKFVFVEPLEWN 60

Query: 61   TSLAPSAFESGYVVSETTVKSEEVDKNGQPLLFLSVPQIKIRSFGQLSRLLLIAKTGKLK 120
            TSLAPSAFESGYVVSETTVKSEEVDKNGQPLLFLSVPQIKIRSFGQLSRLLLIAKTGKLK
Sbjct: 61   TSLAPSAFESGYVVSETTVKSEEVDKNGQPLLFLSVPQIKIRSFGQLSRLLLIAKTGKLK 120

Query: 121  EAQACVEANRDPIVKILGSDYNTMKENSIALNILGKITRDDDPESEIKMKIAMLLKQLDL 180
            EAQACVEANRDPIVKILGSDYNTMKENSIALNILGKITRDDDPESEIKMKIAMLLKQLDL
Sbjct: 121  EAQACVEANRDPIVKILGSDYNTMKENSIALNILGKITRDDDPESEIKMKIAMLLKQLDL 180

Query: 181  HLLNHSLKHISLEISLSPMTVKKDIELLKRFSGKGNQTVLESIEYTSDYEFSNGCRAPPW 240
            HLLNHSLKHISLEISLSPMTVKKDIELLKRFSGKGNQTVLESIEYTSDYEFSNGCRAPPW
Sbjct: 181  HLLNHSLKHISLEISLSPMTVKKDIELLKRFSGKGNQTVLESIEYTSDYEFSNGCRAPPW 240

Query: 241  RQIRGEICYVLVKPHDGETLCITCSAGGVFLNGGKTDDEGDVNYERKGSIYKNLVTFLRE 300
            RQIRGEICYVLVKPHDGETLCITCSAGGVFLNGGKTDDEGDVNYERKGSIYKNLVTFLRE
Sbjct: 241  RQIRGEICYVLVKPHDGETLCITCSAGGVFLNGGKTDDEGDVNYERKGSIYKNLVTFLRE 300

Query: 301  KSPKFSENMSKLGISFSEDQQKEKDQLGKAPKKEEAAALRKDISGSDKRSLEKNQINFWR 360
            KSPKFSENMSKLGISFSEDQQKEKDQLGKAPKKEEAAALRKDISGSDKRSLEKNQINFWR
Sbjct: 301  KSPKFSENMSKLGISFSEDQQKEKDQLGKAPKKEEAAALRKDISGSDKRSLEKNQINFWR 360

Query: 361  NQMTKRWEPSLNWKTTVNYKGKGSAKEIQEDKHTGKLEKPRPSVSHGRAQLLRKSAEKIE 420
            NQMTKRWEPSLNWKTTVNYKGKGSAKEIQEDKHTGKLEKPRPSVSHGRAQLLRKSAEKIE
Sbjct: 361  NQMTKRWEPSLNWKTTVNYKGKGSAKEIQEDKHTGKLEKPRPSVSHGRAQLLRKSAEKIE 420

Query: 421  ETVSDSSSESEEDEEPPDHRQEASADLPSEYWQIQKLVKYLKGGNQTATVIALCSMRDFS 480
            ETVSDSSSESEEDEEPPDHRQEASADLPSEYWQIQKLVKYLKGGNQTATVIALCSMRDFS
Sbjct: 421  ETVSDSSSESEEDEEPPDHRQEASADLPSEYWQIQKLVKYLKGGNQTATVIALCSMRDFS 480

Query: 481  LAQETCQLAIRDVGGLEVLINLLETDEVKCKIGSLKILKEISHNPQIRQNIVDLGGLPIM 540
            LAQETCQLAIRDVGGLEVLINLLETDEVKCKIGSLKILKEISHNPQIRQNIVDLGGLPIM
Sbjct: 481  LAQETCQLAIRDVGGLEVLINLLETDEVKCKIGSLKILKEISHNPQIRQNIVDLGGLPIM 540

Query: 541  VNILDSPHKSLKCLAAETIANVAKFKRARRVVRQHGGITKLVALLDCAHDSTKPAQSSLY 600
            VNILDSPHKSLKCLAAETIANVAKFKRARRVVRQHGGITKLVALLDCAHDSTKPAQSSLY
Sbjct: 541  VNILDSPHKSLKCLAAETIANVAKFKRARRVVRQHGGITKLVALLDCAHDSTKPAQSSLY 600

Query: 601  EARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECA 660
            EARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECA
Sbjct: 601  EARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECA 660

Query: 661  SEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKETRDLVRLHGGLKPLA 720
            SEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKETRDLVRLHGGLKPLA
Sbjct: 661  SEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKETRDLVRLHGGLKPLA 720

Query: 721  SLLNNTDNKERLAAVTGAIWKCSISKENVTKFREYKAIETLVGLLTDQPEEVLVNVVGAL 780
            SLLNNTDNKERLAAVTGAIWKCSISKENVTKFREYKAIETLVGLLTDQPEEVLVNVVGAL
Sbjct: 721  SLLNNTDNKERLAAVTGAIWKCSISKENVTKFREYKAIETLVGLLTDQPEEVLVNVVGAL 780

Query: 781  GECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAVEPESMMIIDRLDGV 840
            GECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAVEPESMMIIDRLDGV
Sbjct: 781  GECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAVEPESMMIIDRLDGV 840

Query: 841  RLLWSLLKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFVGGLELIVNLLKSDNKEVLAS 900
            RLLWSLLKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFVGGLELIVNLLKSDNKEVLAS
Sbjct: 841  RLLWSLLKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFVGGLELIVNLLKSDNKEVLAS 900

Query: 901  VCAAITNIAKDQENLAVITDHGVVPLLSKLANTNNNKLRHHLAEAISRCCMWGRNRVAFG 960
            VCAAITNIAKDQENLAVITDHGVVPLLSKLANTNNNKLRHHLAEAISRCCMWGRNRVAFG
Sbjct: 901  VCAAITNIAKDQENLAVITDHGVVPLLSKLANTNNNKLRHHLAEAISRCCMWGRNRVAFG 960

Query: 961  EHKAVAPLVRYLKSNDTNVHRATAQALYQLSEDADNCITMHENGAVKLLLDMVGSPDQDL 1020
            EHKAVAPLVRYLKSNDTNVHRATAQALYQLSEDADNCITMHENGAVKLLLDMVGSPDQDL
Sbjct: 961  EHKAVAPLVRYLKSNDTNVHRATAQALYQLSEDADNCITMHENGAVKLLLDMVGSPDQDL 1020

Query: 1021 QEAAAGCISNIRRLALATEKARYT 1044
            QEAAAGCISNIRRLALATEKARYT
Sbjct: 1021 QEAAAGCISNIRRLALATEKARYT 1044


>gi|239744025 PREDICTED: hypothetical protein XP_002343006 [Homo
           sapiens]
          Length = 265

 Score =  303 bits (777), Expect = 4e-82
 Identities = 153/171 (89%), Positives = 158/171 (92%), Gaps = 3/171 (1%)

Query: 312 LGISFSEDQQKEKDQLGKAPKKEEAAALRKDISGSDKRSLEKNQINFWRNQMTKRWEPSL 371
           +GISF+EDQQKEKDQLGKAPKKE+AAAL KDISGS KRSLEKNQINFWRNQMTKRWEPSL
Sbjct: 35  IGISFNEDQQKEKDQLGKAPKKEKAAALHKDISGSGKRSLEKNQINFWRNQMTKRWEPSL 94

Query: 372 NWKTTVNYKGKGSAKEIQEDKHTGKLEKPRPSVSHGRAQLLRKSAEKIEETVSDSSSESE 431
           NWKTTVNYKGKGSAKEIQEDKHTGKLEKPRPSVSHGRAQLLRKSAEKIEETVSDSSSESE
Sbjct: 95  NWKTTVNYKGKGSAKEIQEDKHTGKLEKPRPSVSHGRAQLLRKSAEKIEETVSDSSSESE 154

Query: 432 EDEEPPDHRQEASADLPSEYWQIQKLVKYLKGGNQTATVIALCSMRDFSLA 482
           EDEEPPDHRQEASADLPSEYWQIQKLVKYLK   Q+   I  C  +DF LA
Sbjct: 155 EDEEPPDHRQEASADLPSEYWQIQKLVKYLKIREQS---IFSCPSKDFMLA 202



 Score = 70.9 bits (172), Expect = 6e-12
 Identities = 34/35 (97%), Positives = 34/35 (97%)

Query: 1  MGVALRKLTQWTAAGHGTGILEITPLNEAILKEII 35
          MGVALRKLTQWTAAGHGTGILEITPLNE ILKEII
Sbjct: 1  MGVALRKLTQWTAAGHGTGILEITPLNEVILKEII 35


>gi|239749766 PREDICTED: similar to armadillo repeat containing 4
           [Homo sapiens]
          Length = 367

 Score =  300 bits (767), Expect = 6e-81
 Identities = 147/151 (97%), Positives = 149/151 (98%)

Query: 312 LGISFSEDQQKEKDQLGKAPKKEEAAALRKDISGSDKRSLEKNQINFWRNQMTKRWEPSL 371
           +GISF+EDQQKEKDQLGKAPKKEEAAAL KDISGS KRSLEKNQINFWRNQMTKRWEPSL
Sbjct: 35  IGISFNEDQQKEKDQLGKAPKKEEAAALHKDISGSGKRSLEKNQINFWRNQMTKRWEPSL 94

Query: 372 NWKTTVNYKGKGSAKEIQEDKHTGKLEKPRPSVSHGRAQLLRKSAEKIEETVSDSSSESE 431
           NWKTTVNYKGKGSAKEIQEDKHTGKLEKPRPSVSHGRAQLLRKSAEKIEETVSDSSSESE
Sbjct: 95  NWKTTVNYKGKGSAKEIQEDKHTGKLEKPRPSVSHGRAQLLRKSAEKIEETVSDSSSESE 154

Query: 432 EDEEPPDHRQEASADLPSEYWQIQKLVKYLK 462
           EDEEPPDHRQEASADLPSEYWQIQKLVKYLK
Sbjct: 155 EDEEPPDHRQEASADLPSEYWQIQKLVKYLK 185



 Score = 70.9 bits (172), Expect = 6e-12
 Identities = 34/35 (97%), Positives = 34/35 (97%)

Query: 1  MGVALRKLTQWTAAGHGTGILEITPLNEAILKEII 35
          MGVALRKLTQWTAAGHGTGILEITPLNE ILKEII
Sbjct: 1  MGVALRKLTQWTAAGHGTGILEITPLNEVILKEII 35


>gi|239755234 PREDICTED: similar to armadillo repeat containing 4
           [Homo sapiens]
          Length = 362

 Score =  299 bits (765), Expect = 1e-80
 Identities = 147/150 (98%), Positives = 148/150 (98%)

Query: 313 GISFSEDQQKEKDQLGKAPKKEEAAALRKDISGSDKRSLEKNQINFWRNQMTKRWEPSLN 372
           GISF+EDQQKEKDQLGKAPKKEEAAAL KDISGS KRSLEKNQINFWRNQMTKRWEPSLN
Sbjct: 31  GISFNEDQQKEKDQLGKAPKKEEAAALHKDISGSGKRSLEKNQINFWRNQMTKRWEPSLN 90

Query: 373 WKTTVNYKGKGSAKEIQEDKHTGKLEKPRPSVSHGRAQLLRKSAEKIEETVSDSSSESEE 432
           WKTTVNYKGKGSAKEIQEDKHTGKLEKPRPSVSHGRAQLLRKSAEKIEETVSDSSSESEE
Sbjct: 91  WKTTVNYKGKGSAKEIQEDKHTGKLEKPRPSVSHGRAQLLRKSAEKIEETVSDSSSESEE 150

Query: 433 DEEPPDHRQEASADLPSEYWQIQKLVKYLK 462
           DEEPPDHRQEASADLPSEYWQIQKLVKYLK
Sbjct: 151 DEEPPDHRQEASADLPSEYWQIQKLVKYLK 180


>gi|189409124 armadillo repeat containing 3 [Homo sapiens]
          Length = 872

 Score = 87.8 bits (216), Expect = 5e-17
 Identities = 97/506 (19%), Positives = 205/506 (40%), Gaps = 19/506 (3%)

Query: 528  RQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVAKFKRARRVVRQHGGITKLVALLDC 587
            +  +++LG +  +  +L    K ++  A      +A     ++++R+   +  ++A    
Sbjct: 60   KTTLLELGAVEPLTKLLTHEDKIVRRNATMIFGILASNNDVKKLLRELDVMNSVIA---- 115

Query: 588  AHDSTKPAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHEN 647
                       L    +V +    +L L + S  +T+K  I + GG+  L RLL +   +
Sbjct: 116  ----------QLAPEEEVVIHEFASLCLANMSAEYTSKVQIFEHGGLEPLIRLLSSPDPD 165

Query: 648  MLIPVVGTLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKETR 707
            +    +  +     +   RA ++    I  ++  L SE   +Q      +   A DKE+R
Sbjct: 166  VKKNSMECIYNLVQDFQCRAKLQELNAIPPILDLLKSEYPVIQLLALKTLGVIANDKESR 225

Query: 708  DLVRLHGGLKPLASLLNNTDNKERLAAVTGAIWKCSISKENVTKFREYKAIETLVGLLTD 767
             ++R + GL  L  +L   +  +        I  C    + + + ++   ++ L+    +
Sbjct: 226  TMLRDNQGLDHLIKILETKELNDLHIEALAVIANCLEDMDTMVQIQQTGGLKKLLSFAEN 285

Query: 768  QP-EEVLVNVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAV 826
                ++  N   A+ +   + ENR +  +    + LV LL   N    +  ++A+ A   
Sbjct: 286  STIPDIQKNAAKAITKAAYDPENRKLFHEQEVEKCLVALLGSENDGTKIAASQAISAMCE 345

Query: 827  EPESMMIIDRLDGVRLLWSLLKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFVGGLELI 886
               S    +   G+  L  LLK+ + +V+ +AA AL   +     A     +   G++ +
Sbjct: 346  NSGSKDFFNN-QGIPQLIQLLKSDNEEVREAAALALAN-LTTCNPANANAAAEADGIDPL 403

Query: 887  VNLLKSDNKEVLASVCAAITNIAKDQENLAVITDHGVVPLLSKLANTNNNKLRHHLAEAI 946
            +NLL S     +A+    +TN+A  +     I +H ++  +     + N  ++   A A+
Sbjct: 404  INLLSSKRDGAIANAATVLTNMAMQEPLRLNIQNHDIMHAIISPLRSANTVVQSKAALAV 463

Query: 947  SRCCMWGRNRVAFGEHKAVAPLVRYLKSNDTNVHRATAQALYQLSEDADNCITMHENGAV 1006
            +        R        + PLV  L+S +  V +  + A+   + D      +   GA+
Sbjct: 464  TATACDVEARTELRNSGGLEPLVELLRSKNDEVRKHASWAVMVCAGDELTANELCRLGAL 523

Query: 1007 KLL--LDMVGSPDQDLQEAAAGCISN 1030
             +L  +++ G+      EAA   + N
Sbjct: 524  DILEEVNVSGTRKNKFSEAAYNKLLN 549



 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 103/445 (23%), Positives = 182/445 (40%), Gaps = 24/445 (5%)

Query: 498 VLINLLETDEVKCKIGSLKILKEISHNPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAE 557
           V+  L   +EV     +   L  +S     +  I + GGL  ++ +L SP   +K  + E
Sbjct: 113 VIAQLAPEEEVVIHEFASLCLANMSAEYTSKVQIFEHGGLEPLIRLLSSPDPDVKKNSME 172

Query: 558 TIANVAKFKRARRVVRQHGGITKLVALLDCAHDSTKPAQSSLYEARDVEVARCGALALWS 617
            I N+ +  + R  +++   I  ++ LL          +S     + + +   G +A   
Sbjct: 173 CIYNLVQDFQCRAKLQELNAIPPILDLL----------KSEYPVIQLLALKTLGVIA--- 219

Query: 618 CSKSHTNKEAIRKAGGIPLLARLLKTSHENML-IPVVGTLQECASEENYRAAIKAERIIE 676
                 ++  +R   G+  L ++L+T   N L I  +  +  C  + +    I+    ++
Sbjct: 220 --NDKESRTMLRDNQGLDHLIKILETKELNDLHIEALAVIANCLEDMDTMVQIQQTGGLK 277

Query: 677 NLVKNL-NSENEQLQEHCAMAIYQCAEDKETRDLVRLHGGLKPLASLLNNTDNKERLAAV 735
            L+    NS    +Q++ A AI + A D E R L       K L +LL + ++  ++AA 
Sbjct: 278 KLLSFAENSTIPDIQKNAAKAITKAAYDPENRKLFHEQEVEKCLVALLGSENDGTKIAAS 337

Query: 736 TGAIWKCSISKENVTKFREYKAIETLVGLLTDQPEEVLVNVVGALGECCQ-ERENRVIVR 794
                 C  S      F   + I  L+ LL    EEV      AL         N     
Sbjct: 338 QAISAMCENSGSK--DFFNNQGIPQLIQLLKSDNEEVREAAALALANLTTCNPANANAAA 395

Query: 795 KCGGIQPLVNLLVGINQALLVNVTKAVGACAVEPESMMIIDRLDGVRLLWSLLKNPHPDV 854
           +  GI PL+NLL       + N    +   A++    + I   D +  + S L++ +  V
Sbjct: 396 EADGIDPLINLLSSKRDGAIANAATVLTNMAMQEPLRLNIQNHDIMHAIISPLRSANTVV 455

Query: 855 KASAAWALCPCIKNAKDAGEMVRSFVGGLELIVNLLKSDNKEVLASVCAAITNIAKDQEN 914
           ++ AA A+     + +   E+  S  GGLE +V LL+S N EV      A+   A D+  
Sbjct: 456 QSKAALAVTATACDVEARTELRNS--GGLEPLVELLRSKNDEVRKHASWAVMVCAGDELT 513

Query: 915 LAVITDHGVVPLLSK--LANTNNNK 937
              +   G + +L +  ++ T  NK
Sbjct: 514 ANELCRLGALDILEEVNVSGTRKNK 538



 Score = 73.9 bits (180), Expect = 7e-13
 Identities = 81/318 (25%), Positives = 137/318 (43%), Gaps = 30/318 (9%)

Query: 454 IQKLVKYLKGGNQTATVIALCSMRDFSLAQETCQLAIRDVGGLEVLINLLETDEVK-CKI 512
           I  ++  LK       ++AL ++   +  +E+ +  +RD  GL+ LI +LET E+    I
Sbjct: 193 IPPILDLLKSEYPVIQLLALKTLGVIANDKES-RTMLRDNQGLDHLIKILETKELNDLHI 251

Query: 513 GSLKILKEISHNPQIRQNIVDLGGLPIMVNILD-SPHKSLKCLAAETIANVAKFKRARRV 571
            +L ++     +      I   GGL  +++  + S    ++  AA+ I   A     R++
Sbjct: 252 EALAVIANCLEDMDTMVQIQQTGGLKKLLSFAENSTIPDIQKNAAKAITKAAYDPENRKL 311

Query: 572 VRQHGGITKLVALLDCAHDSTKPAQSS-------------------------LYEARDVE 606
             +      LVALL   +D TK A S                          L ++ + E
Sbjct: 312 FHEQEVEKCLVALLGSENDGTKIAASQAISAMCENSGSKDFFNNQGIPQLIQLLKSDNEE 371

Query: 607 VARCGALALWSCSKSH-TNKEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECASEENY 665
           V    ALAL + +  +  N  A  +A GI  L  LL +  +  +      L   A +E  
Sbjct: 372 VREAAALALANLTTCNPANANAAAEADGIDPLINLLSSKRDGAIANAATVLTNMAMQEPL 431

Query: 666 RAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKETRDLVRLHGGLKPLASLLNN 725
           R  I+   I+  ++  L S N  +Q   A+A+   A D E R  +R  GGL+PL  LL +
Sbjct: 432 RLNIQNHDIMHAIISPLRSANTVVQSKAALAVTATACDVEARTELRNSGGLEPLVELLRS 491

Query: 726 TDNKERLAAVTGAIWKCS 743
            +++ R  A + A+  C+
Sbjct: 492 KNDEVRKHA-SWAVMVCA 508



 Score = 70.5 bits (171), Expect = 8e-12
 Identities = 80/354 (22%), Positives = 151/354 (42%), Gaps = 46/354 (12%)

Query: 722  LLNNTDNKERLAAVTGAIWKCSIS-KENVTKFREYKAIETLVGLLTDQ------------ 768
            L+ N+  +E LA    AI+K ++  +EN T   E  A+E L  LLT +            
Sbjct: 32   LMLNSPEEEILAKACEAIYKFALKGEENKTTLLELGAVEPLTKLLTHEDKIVRRNATMIF 91

Query: 769  ----------------------------PEEVLVNVVGA--LGECCQERENRVIVRKCGG 798
                                         EEV+++   +  L     E  ++V + + GG
Sbjct: 92   GILASNNDVKKLLRELDVMNSVIAQLAPEEEVVIHEFASLCLANMSAEYTSKVQIFEHGG 151

Query: 799  IQPLVNLLVGINQALLVNVTKAVGACAVEPESMMIIDRLDGVRLLWSLLKNPHPDVKASA 858
            ++PL+ LL   +  +  N  + +     + +    +  L+ +  +  LLK+ +P ++  A
Sbjct: 152  LEPLIRLLSSPDPDVKKNSMECIYNLVQDFQCRAKLQELNAIPPILDLLKSEYPVIQLLA 211

Query: 859  AWALCPCIKNAKDAGEMVRSFVGGLELIVNLLKSDNKEVLASVCAAITNIAKDQENLAVI 918
               L   I N K++  M+R   G   LI  L   +  ++     A I N  +D + +  I
Sbjct: 212  LKTL-GVIANDKESRTMLRDNQGLDHLIKILETKELNDLHIEALAVIANCLEDMDTMVQI 270

Query: 919  TD-HGVVPLLSKLANTNNNKLRHHLAEAISRCCMWGRNRVAFGEHKAVAPLVRYLKSNDT 977
                G+  LLS   N+    ++ + A+AI++      NR  F E +    LV  L S + 
Sbjct: 271  QQTGGLKKLLSFAENSTIPDIQKNAAKAITKAAYDPENRKLFHEQEVEKCLVALLGSEND 330

Query: 978  NVHRATAQALYQLSEDADNCITMHENGAVKLLLDMVGSPDQDLQEAAAGCISNI 1031
                A +QA+  + E++ +      N  +  L+ ++ S +++++EAAA  ++N+
Sbjct: 331  GTKIAASQAISAMCENSGS-KDFFNNQGIPQLIQLLKSDNEEVREAAALALANL 383



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 60/279 (21%), Positives = 122/279 (43%), Gaps = 4/279 (1%)

Query: 754  EYKAIETLVGLLTDQPEEVLVNVVGALGE-CCQERENRVIVRKCGGIQPLVNLLVGINQA 812
            E K   T+V +L    EE+L     A+ +   +  EN+  + + G ++PL  LL   ++ 
Sbjct: 23   ESKKAATVVLMLNSPEEEILAKACEAIYKFALKGEENKTTLLELGAVEPLTKLLTHEDKI 82

Query: 813  LLVNVTKAVGACAVEPESMMIIDRLDGVRLLWSLLKNPHPDVKASAAWALCPCIKNAKDA 872
            +  N T   G  A   +   ++  LD +  + + L  P  +V      +LC    +A+  
Sbjct: 83   VRRNATMIFGILASNNDVKKLLRELDVMNSVIAQLA-PEEEVVIHEFASLCLANMSAEYT 141

Query: 873  GEMVRSFVGGLELIVNLLKSDNKEVLASVCAAITNIAKDQENLAVITDHGVVPLLSKLAN 932
             ++     GGLE ++ LL S + +V  +    I N+ +D +  A + +   +P +  L  
Sbjct: 142  SKVQIFEHGGLEPLIRLLSSPDPDVKKNSMECIYNLVQDFQCRAKLQELNAIPPILDLLK 201

Query: 933  TNNNKLRHHLAEAISRCCMWGRNRVAFGEHKAVAPLVRYLKSNDTN-VHRATAQALYQLS 991
            +    ++    + +        +R    +++ +  L++ L++ + N +H      +    
Sbjct: 202  SEYPVIQLLALKTLGVIANDKESRTMLRDNQGLDHLIKILETKELNDLHIEALAVIANCL 261

Query: 992  EDADNCITMHENGAVKLLLDMV-GSPDQDLQEAAAGCIS 1029
            ED D  + + + G +K LL     S   D+Q+ AA  I+
Sbjct: 262  EDMDTMVQIQQTGGLKKLLSFAENSTIPDIQKNAAKAIT 300



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 34/148 (22%), Positives = 68/148 (45%), Gaps = 2/148 (1%)

Query: 886  IVNLLKSDNKEVLASVCAAITNIA-KDQENLAVITDHGVVPLLSKLANTNNNKLRHHLAE 944
            +V +L S  +E+LA  C AI   A K +EN   + + G V  L+KL    +  +R +   
Sbjct: 30   VVLMLNSPEEEILAKACEAIYKFALKGEENKTTLLELGAVEPLTKLLTHEDKIVRRNATM 89

Query: 945  AISRCCMWGRNRVAFGEHKAVAPLVRYLK-SNDTNVHRATAQALYQLSEDADNCITMHEN 1003
                       +    E   +  ++  L    +  +H   +  L  +S +  + + + E+
Sbjct: 90   IFGILASNNDVKKLLRELDVMNSVIAQLAPEEEVVIHEFASLCLANMSAEYTSKVQIFEH 149

Query: 1004 GAVKLLLDMVGSPDQDLQEAAAGCISNI 1031
            G ++ L+ ++ SPD D+++ +  CI N+
Sbjct: 150  GGLEPLIRLLSSPDPDVKKNSMECIYNL 177


>gi|91206450 ankyrin and armadillo repeat containing [Homo sapiens]
          Length = 1363

 Score = 86.3 bits (212), Expect = 1e-16
 Identities = 114/471 (24%), Positives = 207/471 (43%), Gaps = 38/471 (8%)

Query: 457  LVKYLKGGNQTATVIALCSMRDFSLAQETCQLAIRDVGGLEVLINLLETDEVKCKIGSLK 516
            LV+ L+  +    ++A+ S+    LA +     I D G +  LINLL++ ++K +  ++ 
Sbjct: 634  LVEMLQCESYKRRMMAVMSLEVICLANDQYWRCILDAGTIPALINLLKSSKIKLQCKTVG 693

Query: 517  ILKEISHNPQIRQNIVDLGGLPIMVNIL--DSPHKSLKCLAAETIANVAKFKRARRVVRQ 574
            +L  IS +      +V+ GG+P ++N+L  D P    +C  A  + ++A+ +  + V+ +
Sbjct: 694  LLSNISTHKSAVHALVEAGGIPSLINLLVCDEPEVHSRC--AVILYDIAQCEN-KDVIAK 750

Query: 575  HGGITKLVALLDCAHDSTKPAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGI 634
            + GI  L+ LL+   ++             V V  C  +    C  +  N+ A+R+  G+
Sbjct: 751  YNGIPSLINLLNLNIENVL-----------VNVMNCIRVL---CIGNENNQRAVREHKGL 796

Query: 635  PLLARLLKTSHENMLIPVVGTLQECASE-ENYRAAIKAERIIENLVKNLNSENEQLQEHC 693
            P L R L +  + +       + E   + +  + AI  E  I  LV     +   +Q   
Sbjct: 797  PYLIRFLSSDSDVLKAVSSAAIAEVGRDNKEIQDAIAMEGAIPPLVALFKGKQISVQMKG 856

Query: 694  AMAIYQCAEDKETRDLVRLHGGL-KPLASLLN--NTDNKERLAAVTGAIWKCSISKEN-V 749
            AMA+   A          L   L K L  LL     D KE+ A    A+   ++ ++  +
Sbjct: 857  AMAVESLASHNALIQKAFLEKSLTKYLLKLLKAFQIDVKEQGAVALWALAGQTLKQQKYM 916

Query: 750  TKFREYKAIETLVGLLTDQPEEVLVNVVGALGECCQERENRVIVRKCGGIQPLVNLL--V 807
             +   Y  I  ++   + + + V    V AL +  +  +N++   +  GI PLV LL   
Sbjct: 917  AEQIGYSFIINMLLSPSAKMQYVGGEAVIALSKDSRMHQNQIC--EGNGIAPLVRLLRIS 974

Query: 808  GINQALLVNVTKAVGACAV------EPESMMIIDRLDGVRLLWSLLKN-PHPDVKASAAW 860
             I +  L++V +AVG+  +       P S   +   +   +L  LL+N P P++K   A+
Sbjct: 975  TIAEGTLLSVIRAVGSICIGVAHTSNPVSQQFVVDENAFPVLIQLLRNHPSPNIKVEVAF 1034

Query: 861  ALCPCIKNAKDAGEMVRSFVGGLEL--IVNLLKSDNKEVLASVCAAITNIA 909
            +L  CI    D  +       G E   ++ LL S  K++      A+T  A
Sbjct: 1035 SLA-CIVLGNDVLQKDLHENEGFEYADVLYLLHSTEKDICLRAGYALTLFA 1084



 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 34/114 (29%), Positives = 54/114 (47%), Gaps = 2/114 (1%)

Query: 881 GGLELIVNLLKSDNKEVLASVCAAITNIAKDQENLAVITDHGVVPLLSKLANTNNNKLRH 940
           GG+  ++NLL  D  EV  S CA I       EN  VI  +  +P L  L N N   +  
Sbjct: 712 GGIPSLINLLVCDEPEV-HSRCAVILYDIAQCENKDVIAKYNGIPSLINLLNLNIENVLV 770

Query: 941 HLAEAISRCCMWG-RNRVAFGEHKAVAPLVRYLKSNDTNVHRATAQALYQLSED 993
           ++   I   C+    N+ A  EHK +  L+R+L S+   +   ++ A+ ++  D
Sbjct: 771 NVMNCIRVLCIGNENNQRAVREHKGLPYLIRFLSSDSDVLKAVSSAAIAEVGRD 824



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 72/315 (22%), Positives = 122/315 (38%), Gaps = 19/315 (6%)

Query: 717  KPLASLLNNTDNKERLAAVTGAIWKCSISKENVTKFREYKAIETLVGLLTDQPEEVLVNV 776
            K L  +L     K R+ AV      C  + +      +   I  L+ LL     ++    
Sbjct: 632  KTLVEMLQCESYKRRMMAVMSLEVICLANDQYWRCILDAGTIPALINLLKSSKIKLQCKT 691

Query: 777  VGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAV------EPES 830
            VG L      +     + + GGI  L+NLLV        +  +    CAV      + E+
Sbjct: 692  VGLLSNISTHKSAVHALVEAGGIPSLINLLV-------CDEPEVHSRCAVILYDIAQCEN 744

Query: 831  MMIIDRLDGVRLLWSLLKNPHPDVKASAAWAL-CPCIKNAKDAGEMVRSFVGGLELIVNL 889
              +I + +G+  L +LL     +V  +    +   CI N  +    VR   G L  ++  
Sbjct: 745  KDVIAKYNGIPSLINLLNLNIENVLVNVMNCIRVLCIGNENNQ-RAVREHKG-LPYLIRF 802

Query: 890  LKSDNKEVLASVCAAITNIAKDQENLA-VITDHGVVPLLSKLANTNNNKLRHHLAEAISR 948
            L SD+  + A   AAI  + +D + +   I   G +P L  L       ++   A A+  
Sbjct: 803  LSSDSDVLKAVSSAAIAEVGRDNKEIQDAIAMEGAIPPLVALFKGKQISVQMKGAMAVES 862

Query: 949  CCMWGR-NRVAFGEHKAVAPLVRYLKSNDTNVHRATAQALYQLS-EDADNCITMHENGAV 1006
                    + AF E      L++ LK+   +V    A AL+ L+ +       M E    
Sbjct: 863  LASHNALIQKAFLEKSLTKYLLKLLKAFQIDVKEQGAVALWALAGQTLKQQKYMAEQIGY 922

Query: 1007 KLLLDMVGSPDQDLQ 1021
              +++M+ SP   +Q
Sbjct: 923  SFIINMLLSPSAKMQ 937



 Score = 32.0 bits (71), Expect = 3.1
 Identities = 29/157 (18%), Positives = 65/157 (41%), Gaps = 8/157 (5%)

Query: 881  GGLELIVNLLKSDNKEVLASVCAAITNIAKDQENLAVITDHGVVPLLSKLANTNNNKLRH 940
            G +  ++NLLKS   ++       ++NI+  +  +  + + G +P L  L   +  ++  
Sbjct: 671  GTIPALINLLKSSKIKLQCKTVGLLSNISTHKSAVHALVEAGGIPSLINLLVCDEPEVHS 730

Query: 941  HLAEA---ISRCCMWGRNRVAFGEHKAVAPLVRYLKSNDTNVHRATAQALYQLS-EDADN 996
              A     I++C     N+    ++  +  L+  L  N  NV       +  L   + +N
Sbjct: 731  RCAVILYDIAQC----ENKDVIAKYNGIPSLINLLNLNIENVLVNVMNCIRVLCIGNENN 786

Query: 997  CITMHENGAVKLLLDMVGSPDQDLQEAAAGCISNIRR 1033
               + E+  +  L+  + S    L+  ++  I+ + R
Sbjct: 787  QRAVREHKGLPYLIRFLSSDSDVLKAVSSAAIAEVGR 823


>gi|4504811 junction plakoglobin [Homo sapiens]
          Length = 745

 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 111/528 (21%), Positives = 208/528 (39%), Gaps = 52/528 (9%)

Query: 537  LPIMVNILDSPHKSLKCLAAETIANVAKFKRARRVVRQHGGITKLVALLDCAHDSTKPAQ 596
            LP +  +L+     +   AA  +  ++K + +RR +    G  +LVA +     +T    
Sbjct: 144  LPELTKLLNDEDPVVVTKAAMIVNQLSKKEASRRALM---GSPQLVAAVVRTMQNTS--- 197

Query: 597  SSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVVGTL 656
                   D++ ARC    L + S       AI K+GGIP L R+L +  E++L   + TL
Sbjct: 198  -------DLDTARCTTSILHNLSHHREGLLAIFKSGGIPALVRMLSSPVESVLFYAITTL 250

Query: 657  QE-CASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCA-EDKETRDLVRLHG 714
                  +E  + A++    ++ +V  LN  N +        +   A  ++E++ ++  +G
Sbjct: 251  HNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAITTDCLQLLAYGNQESKLIILANG 310

Query: 715  GLKPLASLLNNTDNKERLAAVTGAIWKCSISKENVTKFREYKAIETLVGLLTDQPEEVLV 774
            G + L  ++ N   ++ L   +  +   S+   N     E   ++ L   LT     ++ 
Sbjct: 311  GPQALVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPAIVEAGGMQALGKHLTSNSPRLVQ 370

Query: 775  NVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNV-TKAVG-----ACAVEP 828
            N +  L      R    +  K  G++ ++ +LV       VNV T A G      C    
Sbjct: 371  NCLWTL------RNLSDVATKQEGLESVLKILVNQLSVDDVNVLTCATGTLSNLTCNNSK 424

Query: 829  ESMMIIDRLDGVRLLWSLLKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFVG---GLEL 885
               ++        L+ ++L+    D     A      + +     EM ++ V    G+  
Sbjct: 425  NKTLVTQNSGVEALIHAILRAGDKDDITEPAVCALRHLTSRHPEAEMAQNSVRLNYGIPA 484

Query: 886  IVNLLKSDNK-EVLASVCAAITNIAKDQENLAVITDHGVVPLLSKLANTNNNKLRHHLA- 943
            IV LL   N+  ++ +    I N+A    N A + +  V+P L +L    +   + H+A 
Sbjct: 485  IVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQLLVKAHQDAQRHVAA 544

Query: 944  ------------EAISRCCMWG--------RNRVAFGEHKAVAPLVRYLKSNDTNVHRAT 983
                        E I   C            NR+       +   V+ L S+  N+ R  
Sbjct: 545  GTQQPYTDGVRMEEIVEGCTGALHILARDPMNRMEIFRLNTIPLFVQLLYSSVENIQRVA 604

Query: 984  AQALYQLSEDADNCITMHENGAVKLLLDMVGSPDQDLQEAAAGCISNI 1031
            A  L +L++D +    +   GA   L++++ S ++     AA  +  I
Sbjct: 605  AGVLCELAQDKEAADAIDAEGASAPLMELLHSRNEGTATYAAAVLFRI 652



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 113/507 (22%), Positives = 198/507 (39%), Gaps = 60/507 (11%)

Query: 501 NLLETDEVKCKIGSLKILKEISHNPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIA 560
           N  + D  +C   +  IL  +SH+ +    I   GG+P +V +L SP +S+   A  T+ 
Sbjct: 195 NTSDLDTARC---TTSILHNLSHHREGLLAIFKSGGIPALVRMLSSPVESVLFYAITTLH 251

Query: 561 NVAKFKR-ARRVVRQHGGITKLVALLDCAHDSTKPAQSSLYEARDVEVARCGALALWSCS 619
           N+  ++  A+  VR   G+ K+V LL    +   P   ++          C  L  +   
Sbjct: 252 NLLLYQEGAKMAVRLADGLQKMVPLL----NKNNPKFLAI-------TTDCLQLLAYGNQ 300

Query: 620 KSHTNKEAIRKAGGIPLLARLLKT-SHENMLIPVVGTLQECASEENYRAAIKAERIIENL 678
           +S   K  I   GG   L ++++  S+E +L      L+  +   + + AI     ++ L
Sbjct: 301 ES---KLIILANGGPQALVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPAIVEAGGMQAL 357

Query: 679 VKNLNSENEQLQEHCAMAIYQCAEDKETRDLVRLHGGLKPLASLLNN---TDNKERLAAV 735
            K+L S + +L ++C   +      +   D+     GL+ +  +L N    D+   L   
Sbjct: 358 GKHLTSNSPRLVQNCLWTL------RNLSDVATKQEGLESVLKILVNQLSVDDVNVLTCA 411

Query: 736 TGAI--WKCSISKENVTKFREYKAIETLVG--LLTDQPEEVLVNVVGALGECCQERENRV 791
           TG +    C+ SK N T   +   +E L+   L     +++    V AL           
Sbjct: 412 TGTLSNLTCNNSK-NKTLVTQNSGVEALIHAILRAGDKDDITEPAVCALRHLTSRHPEAE 470

Query: 792 I----VRKCGGIQPLVNLLVGINQALLVNVT-KAVGACAVEPESMMIIDRLDGVRLLWSL 846
           +    VR   GI  +V LL   NQ  LV  T   +   A+ P +   +     +  L  L
Sbjct: 471 MAQNSVRLNYGIPAIVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQL 530

Query: 847 LKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFVGGLELIVNLLKSDNKEVLASVCAAIT 906
           L   H D +   A            AG   + +  G+ +         +E++     A+ 
Sbjct: 531 LVKAHQDAQRHVA------------AGTQ-QPYTDGVRM---------EEIVEGCTGALH 568

Query: 907 NIAKDQENLAVITDHGVVPLLSKLANTNNNKLRHHLAEAISRCCMWGRNRVAFGEHKAVA 966
            +A+D  N   I     +PL  +L  ++   ++   A  +           A     A A
Sbjct: 569 ILARDPMNRMEIFRLNTIPLFVQLLYSSVENIQRVAAGVLCELAQDKEAADAIDAEGASA 628

Query: 967 PLVRYLKSNDTNVHRATAQALYQLSED 993
           PL+  L S +       A  L+++SED
Sbjct: 629 PLMELLHSRNEGTATYAAAVLFRISED 655



 Score = 57.8 bits (138), Expect = 5e-08
 Identities = 95/470 (20%), Positives = 193/470 (41%), Gaps = 52/470 (11%)

Query: 454 IQKLVKYLKGGNQTATVIALCSMRDFSLAQETCQLAIRDVGGLEVLINLLETDEVKCKIG 513
           I  LV+ L    ++    A+ ++ +  L QE  ++A+R   GL+ ++ LL  +  K    
Sbjct: 228 IPALVRMLSSPVESVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAI 287

Query: 514 SLKILKEISH-NPQIRQNIVDLGGLPIMVNIL-DSPHKSLKCLAAETIANVAKFKRARRV 571
           +   L+ +++ N + +  I+  GG   +V I+ +  ++ L    +  +  ++     +  
Sbjct: 288 TTDCLQLLAYGNQESKLIILANGGPQALVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPA 347

Query: 572 VRQHGGITKLVALLDCAHDSTKPAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKA 631
           + + GG+  L   L    +S +  Q+ L+  R++             S   T +E +   
Sbjct: 348 IVEAGGMQALGKHL--TSNSPRLVQNCLWTLRNL-------------SDVATKQEGLESV 392

Query: 632 GGIPLLARLLKTSHENMLIPVVGTLQE--CASEENYRAAIKAERIIENLVKNL--NSENE 687
             + +L   L     N+L    GTL    C + +N +  +     +E L+  +    + +
Sbjct: 393 --LKILVNQLSVDDVNVLTCATGTLSNLTCNNSKN-KTLVTQNSGVEALIHAILRAGDKD 449

Query: 688 QLQEHCAMAIYQCA----EDKETRDLVRLHGGLKPLASLLNNTDNKERLAAVTGAIWKCS 743
            + E    A+        E +  ++ VRL+ G+  +  LLN  +    + A  G I   +
Sbjct: 450 DITEPAVCALRHLTSRHPEAEMAQNSVRLNYGIPAIVKLLNQPNQWPLVKATIGLIRNLA 509

Query: 744 ISKENVTKFREYKAIETLVGLLTDQPEEVLVNVVGALGECCQERENRVIVRKCGGIQPLV 803
           +   N    +E   I  LV LL    ++   +V                    G  QP  
Sbjct: 510 LCPANHAPLQEAAVIPRLVQLLVKAHQDAQRHVA------------------AGTQQPYT 551

Query: 804 NLLVGIN-QALLVNVTKAVGACAVEPESMMIIDRLDGVRLLWSLLKNPHPDVKASAAWAL 862
           +   G+  + ++   T A+   A +P + M I RL+ + L   LL +   +++  AA  L
Sbjct: 552 D---GVRMEEIVEGCTGALHILARDPMNRMEIFRLNTIPLFVQLLYSSVENIQRVAAGVL 608

Query: 863 CPCIKNAKDAGEMVRSFVGGLELIVNLLKSDNKEVLASVCAAITNIAKDQ 912
           C   ++ K+A + + +  G    ++ LL S N+       A +  I++D+
Sbjct: 609 CELAQD-KEAADAIDA-EGASAPLMELLHSRNEGTATYAAAVLFRISEDK 656


>gi|12056468 junction plakoglobin [Homo sapiens]
          Length = 745

 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 111/528 (21%), Positives = 208/528 (39%), Gaps = 52/528 (9%)

Query: 537  LPIMVNILDSPHKSLKCLAAETIANVAKFKRARRVVRQHGGITKLVALLDCAHDSTKPAQ 596
            LP +  +L+     +   AA  +  ++K + +RR +    G  +LVA +     +T    
Sbjct: 144  LPELTKLLNDEDPVVVTKAAMIVNQLSKKEASRRALM---GSPQLVAAVVRTMQNTS--- 197

Query: 597  SSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVVGTL 656
                   D++ ARC    L + S       AI K+GGIP L R+L +  E++L   + TL
Sbjct: 198  -------DLDTARCTTSILHNLSHHREGLLAIFKSGGIPALVRMLSSPVESVLFYAITTL 250

Query: 657  QE-CASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCA-EDKETRDLVRLHG 714
                  +E  + A++    ++ +V  LN  N +        +   A  ++E++ ++  +G
Sbjct: 251  HNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAITTDCLQLLAYGNQESKLIILANG 310

Query: 715  GLKPLASLLNNTDNKERLAAVTGAIWKCSISKENVTKFREYKAIETLVGLLTDQPEEVLV 774
            G + L  ++ N   ++ L   +  +   S+   N     E   ++ L   LT     ++ 
Sbjct: 311  GPQALVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPAIVEAGGMQALGKHLTSNSPRLVQ 370

Query: 775  NVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNV-TKAVG-----ACAVEP 828
            N +  L      R    +  K  G++ ++ +LV       VNV T A G      C    
Sbjct: 371  NCLWTL------RNLSDVATKQEGLESVLKILVNQLSVDDVNVLTCATGTLSNLTCNNSK 424

Query: 829  ESMMIIDRLDGVRLLWSLLKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFVG---GLEL 885
               ++        L+ ++L+    D     A      + +     EM ++ V    G+  
Sbjct: 425  NKTLVTQNSGVEALIHAILRAGDKDDITEPAVCALRHLTSRHPEAEMAQNSVRLNYGIPA 484

Query: 886  IVNLLKSDNK-EVLASVCAAITNIAKDQENLAVITDHGVVPLLSKLANTNNNKLRHHLA- 943
            IV LL   N+  ++ +    I N+A    N A + +  V+P L +L    +   + H+A 
Sbjct: 485  IVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQLLVKAHQDAQRHVAA 544

Query: 944  ------------EAISRCCMWG--------RNRVAFGEHKAVAPLVRYLKSNDTNVHRAT 983
                        E I   C            NR+       +   V+ L S+  N+ R  
Sbjct: 545  GTQQPYTDGVRMEEIVEGCTGALHILARDPMNRMEIFRLNTIPLFVQLLYSSVENIQRVA 604

Query: 984  AQALYQLSEDADNCITMHENGAVKLLLDMVGSPDQDLQEAAAGCISNI 1031
            A  L +L++D +    +   GA   L++++ S ++     AA  +  I
Sbjct: 605  AGVLCELAQDKEAADAIDAEGASAPLMELLHSRNEGTATYAAAVLFRI 652



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 113/507 (22%), Positives = 198/507 (39%), Gaps = 60/507 (11%)

Query: 501 NLLETDEVKCKIGSLKILKEISHNPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIA 560
           N  + D  +C   +  IL  +SH+ +    I   GG+P +V +L SP +S+   A  T+ 
Sbjct: 195 NTSDLDTARC---TTSILHNLSHHREGLLAIFKSGGIPALVRMLSSPVESVLFYAITTLH 251

Query: 561 NVAKFKR-ARRVVRQHGGITKLVALLDCAHDSTKPAQSSLYEARDVEVARCGALALWSCS 619
           N+  ++  A+  VR   G+ K+V LL    +   P   ++          C  L  +   
Sbjct: 252 NLLLYQEGAKMAVRLADGLQKMVPLL----NKNNPKFLAI-------TTDCLQLLAYGNQ 300

Query: 620 KSHTNKEAIRKAGGIPLLARLLKT-SHENMLIPVVGTLQECASEENYRAAIKAERIIENL 678
           +S   K  I   GG   L ++++  S+E +L      L+  +   + + AI     ++ L
Sbjct: 301 ES---KLIILANGGPQALVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPAIVEAGGMQAL 357

Query: 679 VKNLNSENEQLQEHCAMAIYQCAEDKETRDLVRLHGGLKPLASLLNN---TDNKERLAAV 735
            K+L S + +L ++C   +      +   D+     GL+ +  +L N    D+   L   
Sbjct: 358 GKHLTSNSPRLVQNCLWTL------RNLSDVATKQEGLESVLKILVNQLSVDDVNVLTCA 411

Query: 736 TGAI--WKCSISKENVTKFREYKAIETLVG--LLTDQPEEVLVNVVGALGECCQERENRV 791
           TG +    C+ SK N T   +   +E L+   L     +++    V AL           
Sbjct: 412 TGTLSNLTCNNSK-NKTLVTQNSGVEALIHAILRAGDKDDITEPAVCALRHLTSRHPEAE 470

Query: 792 I----VRKCGGIQPLVNLLVGINQALLVNVT-KAVGACAVEPESMMIIDRLDGVRLLWSL 846
           +    VR   GI  +V LL   NQ  LV  T   +   A+ P +   +     +  L  L
Sbjct: 471 MAQNSVRLNYGIPAIVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQL 530

Query: 847 LKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFVGGLELIVNLLKSDNKEVLASVCAAIT 906
           L   H D +   A            AG   + +  G+ +         +E++     A+ 
Sbjct: 531 LVKAHQDAQRHVA------------AGTQ-QPYTDGVRM---------EEIVEGCTGALH 568

Query: 907 NIAKDQENLAVITDHGVVPLLSKLANTNNNKLRHHLAEAISRCCMWGRNRVAFGEHKAVA 966
            +A+D  N   I     +PL  +L  ++   ++   A  +           A     A A
Sbjct: 569 ILARDPMNRMEIFRLNTIPLFVQLLYSSVENIQRVAAGVLCELAQDKEAADAIDAEGASA 628

Query: 967 PLVRYLKSNDTNVHRATAQALYQLSED 993
           PL+  L S +       A  L+++SED
Sbjct: 629 PLMELLHSRNEGTATYAAAVLFRISED 655



 Score = 57.8 bits (138), Expect = 5e-08
 Identities = 95/470 (20%), Positives = 193/470 (41%), Gaps = 52/470 (11%)

Query: 454 IQKLVKYLKGGNQTATVIALCSMRDFSLAQETCQLAIRDVGGLEVLINLLETDEVKCKIG 513
           I  LV+ L    ++    A+ ++ +  L QE  ++A+R   GL+ ++ LL  +  K    
Sbjct: 228 IPALVRMLSSPVESVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAI 287

Query: 514 SLKILKEISH-NPQIRQNIVDLGGLPIMVNIL-DSPHKSLKCLAAETIANVAKFKRARRV 571
           +   L+ +++ N + +  I+  GG   +V I+ +  ++ L    +  +  ++     +  
Sbjct: 288 TTDCLQLLAYGNQESKLIILANGGPQALVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPA 347

Query: 572 VRQHGGITKLVALLDCAHDSTKPAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKA 631
           + + GG+  L   L    +S +  Q+ L+  R++             S   T +E +   
Sbjct: 348 IVEAGGMQALGKHL--TSNSPRLVQNCLWTLRNL-------------SDVATKQEGLESV 392

Query: 632 GGIPLLARLLKTSHENMLIPVVGTLQE--CASEENYRAAIKAERIIENLVKNL--NSENE 687
             + +L   L     N+L    GTL    C + +N +  +     +E L+  +    + +
Sbjct: 393 --LKILVNQLSVDDVNVLTCATGTLSNLTCNNSKN-KTLVTQNSGVEALIHAILRAGDKD 449

Query: 688 QLQEHCAMAIYQCA----EDKETRDLVRLHGGLKPLASLLNNTDNKERLAAVTGAIWKCS 743
            + E    A+        E +  ++ VRL+ G+  +  LLN  +    + A  G I   +
Sbjct: 450 DITEPAVCALRHLTSRHPEAEMAQNSVRLNYGIPAIVKLLNQPNQWPLVKATIGLIRNLA 509

Query: 744 ISKENVTKFREYKAIETLVGLLTDQPEEVLVNVVGALGECCQERENRVIVRKCGGIQPLV 803
           +   N    +E   I  LV LL    ++   +V                    G  QP  
Sbjct: 510 LCPANHAPLQEAAVIPRLVQLLVKAHQDAQRHVA------------------AGTQQPYT 551

Query: 804 NLLVGIN-QALLVNVTKAVGACAVEPESMMIIDRLDGVRLLWSLLKNPHPDVKASAAWAL 862
           +   G+  + ++   T A+   A +P + M I RL+ + L   LL +   +++  AA  L
Sbjct: 552 D---GVRMEEIVEGCTGALHILARDPMNRMEIFRLNTIPLFVQLLYSSVENIQRVAAGVL 608

Query: 863 CPCIKNAKDAGEMVRSFVGGLELIVNLLKSDNKEVLASVCAAITNIAKDQ 912
           C   ++ K+A + + +  G    ++ LL S N+       A +  I++D+
Sbjct: 609 CELAQD-KEAADAIDA-EGASAPLMELLHSRNEGTATYAAAVLFRISEDK 656


>gi|148227672 catenin (cadherin-associated protein), beta 1, 88kDa
           [Homo sapiens]
          Length = 781

 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 66/232 (28%), Positives = 104/232 (44%), Gaps = 14/232 (6%)

Query: 487 QLAIRDVGGLEVLINLL-----ETDEVKCKIGSLKILKEISHNPQIRQNIVDLG-GLPIM 540
           ++ +  VGG+E L+  +       D  +  I +L+ L       ++ QN V L  GLP++
Sbjct: 435 KMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVV 494

Query: 541 VNILDSP-HKSLKCLAAETIANVAKFKRARRVVRQHGGITKLVALLDCAHDSTK------ 593
           V +L  P H  L       I N+A        +R+ G I +LV LL  AH  T+      
Sbjct: 495 VKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMG 554

Query: 594 -PAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPV 652
              Q  +   R  E+      AL   ++   N+  IR    IPL  +LL +  EN+    
Sbjct: 555 GTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVA 614

Query: 653 VGTLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDK 704
            G L E A ++    AI+AE     L + L+S NE +  + A  +++ +EDK
Sbjct: 615 AGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSEDK 666



 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 105/458 (22%), Positives = 193/458 (42%), Gaps = 45/458 (9%)

Query: 598  SLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQ 657
            ++    DVE ARC A  L + S       AI K+GGIP L ++L +  +++L   + TL 
Sbjct: 201  TMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLH 260

Query: 658  E-CASEENYRAAIKAERIIENLVKNLNSENEQ---LQEHCAMAIYQCAEDKETRDLVRLH 713
                 +E  + A++    ++ +V  LN  N +   +   C   +     ++E++ ++   
Sbjct: 261  NLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQIL--AYGNQESKLIILAS 318

Query: 714  GGLKPLASLLNNTDNKERLAAVTGAIWK-CSISKENVTKFREYKAIETLVGLLTDQPEEV 772
            GG + L +++  T   E+L   T  + K  S+   N     E   ++ L   LTD  + +
Sbjct: 319  GGPQALVNIM-RTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRL 377

Query: 773  LVNVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVN-VTKAVGACA----VE 827
            + N +  L      R       K  G++ L+  LV +  +  +N VT A G  +      
Sbjct: 378  VQNCLWTL------RNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNN 431

Query: 828  PESMMIIDRLDGVRLL--WSLLKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFVG---G 882
             ++ M++ ++ G+  L    L      D+   A  AL       ++A EM ++ V    G
Sbjct: 432  YKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEA-EMAQNAVRLHYG 490

Query: 883  LELIVNLLKSDNK-EVLASVCAAITNIAKDQENLAVITDHGVVPLLSKLANTNNNKLRHH 941
            L ++V LL   +   ++ +    I N+A    N A + + G +P L +L       +R H
Sbjct: 491  LPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL------VRAH 544

Query: 942  LAEAISRCCMWGRNRVAFGEHKAVAPLVRYLKSNDTNVHRATAQALYQLSEDADNCITMH 1001
              +   R    G  +  F E   +  +V                AL+ L+ D  N I + 
Sbjct: 545  --QDTQRRTSMGGTQQQFVEGVRMEEIV-----------EGCTGALHILARDVHNRIVIR 591

Query: 1002 ENGAVKLLLDMVGSPDQDLQEAAAGCISNIRRLALATE 1039
                + L + ++ SP +++Q  AAG +  + +   A E
Sbjct: 592  GLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAE 629



 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 117/537 (21%), Positives = 208/537 (38%), Gaps = 101/537 (18%)

Query: 454 IQKLVKYLKGGNQTATVIALCSMRDFSLAQETCQLAIRDVGGLEVLINLLE-TDEVKCKI 512
           I +L K L   +Q     A   +   S  + +    +R    +  ++  ++ T++V+   
Sbjct: 153 IPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETAR 212

Query: 513 GSLKILKEISHNPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVAKFKR-ARRV 571
            +   L  +SH+ +    I   GG+P +V +L SP  S+   A  T+ N+   +  A+  
Sbjct: 213 CTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMA 272

Query: 572 VRQHGGITKLVALLDCAH--------DSTKPAQSSLYEARDVEVARCGALALWSCSKSHT 623
           VR  GG+ K+VALL+  +        D  +       E++ + +A  G  AL +  +++T
Sbjct: 273 VRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYT 332

Query: 624 --------------------NKEAIRKAGGIPLLA--------RLLK------------- 642
                               NK AI +AGG+  L         RL++             
Sbjct: 333 YEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAA 392

Query: 643 TSHENMLIPVVGTLQECASEENYRAAIKAERIIENLVKN--------------------- 681
           T  E M   ++GTL +    ++      A  I+ NL  N                     
Sbjct: 393 TKQEGM-EGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTV 451

Query: 682 -LNSENEQLQEHCAMAIYQCA----EDKETRDLVRLHGGLKPLASLLNNTDNKERLAAVT 736
               + E + E    A+        E +  ++ VRLH GL  +  LL+   +   + A  
Sbjct: 452 LRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATV 511

Query: 737 GAIWKCSISKENVTKFREYKAIETLVGLLTDQPEEVLVNVVGALGECCQERENRVIVRKC 796
           G I   ++   N    RE  AI  LV LL                   Q+ + R      
Sbjct: 512 GLIRNLALCPANHAPLREQGAIPRLVQLLV---------------RAHQDTQRRT---SM 553

Query: 797 GGIQPLVNLLVGIN-QALLVNVTKAVGACAVEPESMMIIDRLDGVRLLWSLLKNPHPDVK 855
           GG Q     + G+  + ++   T A+   A +  + ++I  L+ + L   LL +P  +++
Sbjct: 554 GGTQQ--QFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQ 611

Query: 856 ASAAWALCPCIKNAKDAGEMVRSFVGGLELIVNLLKSDNKEVLASVCAAITNIAKDQ 912
             AA  LC   ++ K+A E + +  G    +  LL S N+ V     A +  +++D+
Sbjct: 612 RVAAGVLCELAQD-KEAAEAIEA-EGATAPLTELLHSRNEGVATYAAAVLFRMSEDK 666


>gi|148233338 catenin (cadherin-associated protein), beta 1, 88kDa
           [Homo sapiens]
          Length = 781

 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 66/232 (28%), Positives = 104/232 (44%), Gaps = 14/232 (6%)

Query: 487 QLAIRDVGGLEVLINLL-----ETDEVKCKIGSLKILKEISHNPQIRQNIVDLG-GLPIM 540
           ++ +  VGG+E L+  +       D  +  I +L+ L       ++ QN V L  GLP++
Sbjct: 435 KMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVV 494

Query: 541 VNILDSP-HKSLKCLAAETIANVAKFKRARRVVRQHGGITKLVALLDCAHDSTK------ 593
           V +L  P H  L       I N+A        +R+ G I +LV LL  AH  T+      
Sbjct: 495 VKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMG 554

Query: 594 -PAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPV 652
              Q  +   R  E+      AL   ++   N+  IR    IPL  +LL +  EN+    
Sbjct: 555 GTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVA 614

Query: 653 VGTLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDK 704
            G L E A ++    AI+AE     L + L+S NE +  + A  +++ +EDK
Sbjct: 615 AGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSEDK 666



 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 105/458 (22%), Positives = 193/458 (42%), Gaps = 45/458 (9%)

Query: 598  SLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQ 657
            ++    DVE ARC A  L + S       AI K+GGIP L ++L +  +++L   + TL 
Sbjct: 201  TMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLH 260

Query: 658  E-CASEENYRAAIKAERIIENLVKNLNSENEQ---LQEHCAMAIYQCAEDKETRDLVRLH 713
                 +E  + A++    ++ +V  LN  N +   +   C   +     ++E++ ++   
Sbjct: 261  NLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQIL--AYGNQESKLIILAS 318

Query: 714  GGLKPLASLLNNTDNKERLAAVTGAIWK-CSISKENVTKFREYKAIETLVGLLTDQPEEV 772
            GG + L +++  T   E+L   T  + K  S+   N     E   ++ L   LTD  + +
Sbjct: 319  GGPQALVNIM-RTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRL 377

Query: 773  LVNVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVN-VTKAVGACA----VE 827
            + N +  L      R       K  G++ L+  LV +  +  +N VT A G  +      
Sbjct: 378  VQNCLWTL------RNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNN 431

Query: 828  PESMMIIDRLDGVRLL--WSLLKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFVG---G 882
             ++ M++ ++ G+  L    L      D+   A  AL       ++A EM ++ V    G
Sbjct: 432  YKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEA-EMAQNAVRLHYG 490

Query: 883  LELIVNLLKSDNK-EVLASVCAAITNIAKDQENLAVITDHGVVPLLSKLANTNNNKLRHH 941
            L ++V LL   +   ++ +    I N+A    N A + + G +P L +L       +R H
Sbjct: 491  LPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL------VRAH 544

Query: 942  LAEAISRCCMWGRNRVAFGEHKAVAPLVRYLKSNDTNVHRATAQALYQLSEDADNCITMH 1001
              +   R    G  +  F E   +  +V                AL+ L+ D  N I + 
Sbjct: 545  --QDTQRRTSMGGTQQQFVEGVRMEEIV-----------EGCTGALHILARDVHNRIVIR 591

Query: 1002 ENGAVKLLLDMVGSPDQDLQEAAAGCISNIRRLALATE 1039
                + L + ++ SP +++Q  AAG +  + +   A E
Sbjct: 592  GLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAE 629



 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 117/537 (21%), Positives = 208/537 (38%), Gaps = 101/537 (18%)

Query: 454 IQKLVKYLKGGNQTATVIALCSMRDFSLAQETCQLAIRDVGGLEVLINLLE-TDEVKCKI 512
           I +L K L   +Q     A   +   S  + +    +R    +  ++  ++ T++V+   
Sbjct: 153 IPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETAR 212

Query: 513 GSLKILKEISHNPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVAKFKR-ARRV 571
            +   L  +SH+ +    I   GG+P +V +L SP  S+   A  T+ N+   +  A+  
Sbjct: 213 CTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMA 272

Query: 572 VRQHGGITKLVALLDCAH--------DSTKPAQSSLYEARDVEVARCGALALWSCSKSHT 623
           VR  GG+ K+VALL+  +        D  +       E++ + +A  G  AL +  +++T
Sbjct: 273 VRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYT 332

Query: 624 --------------------NKEAIRKAGGIPLLA--------RLLK------------- 642
                               NK AI +AGG+  L         RL++             
Sbjct: 333 YEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAA 392

Query: 643 TSHENMLIPVVGTLQECASEENYRAAIKAERIIENLVKN--------------------- 681
           T  E M   ++GTL +    ++      A  I+ NL  N                     
Sbjct: 393 TKQEGM-EGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTV 451

Query: 682 -LNSENEQLQEHCAMAIYQCA----EDKETRDLVRLHGGLKPLASLLNNTDNKERLAAVT 736
               + E + E    A+        E +  ++ VRLH GL  +  LL+   +   + A  
Sbjct: 452 LRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATV 511

Query: 737 GAIWKCSISKENVTKFREYKAIETLVGLLTDQPEEVLVNVVGALGECCQERENRVIVRKC 796
           G I   ++   N    RE  AI  LV LL                   Q+ + R      
Sbjct: 512 GLIRNLALCPANHAPLREQGAIPRLVQLLV---------------RAHQDTQRRT---SM 553

Query: 797 GGIQPLVNLLVGIN-QALLVNVTKAVGACAVEPESMMIIDRLDGVRLLWSLLKNPHPDVK 855
           GG Q     + G+  + ++   T A+   A +  + ++I  L+ + L   LL +P  +++
Sbjct: 554 GGTQQ--QFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQ 611

Query: 856 ASAAWALCPCIKNAKDAGEMVRSFVGGLELIVNLLKSDNKEVLASVCAAITNIAKDQ 912
             AA  LC   ++ K+A E + +  G    +  LL S N+ V     A +  +++D+
Sbjct: 612 RVAAGVLCELAQD-KEAAEAIEA-EGATAPLTELLHSRNEGVATYAAAVLFRMSEDK 666


>gi|4503131 catenin (cadherin-associated protein), beta 1, 88kDa
           [Homo sapiens]
          Length = 781

 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 66/232 (28%), Positives = 104/232 (44%), Gaps = 14/232 (6%)

Query: 487 QLAIRDVGGLEVLINLL-----ETDEVKCKIGSLKILKEISHNPQIRQNIVDLG-GLPIM 540
           ++ +  VGG+E L+  +       D  +  I +L+ L       ++ QN V L  GLP++
Sbjct: 435 KMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVV 494

Query: 541 VNILDSP-HKSLKCLAAETIANVAKFKRARRVVRQHGGITKLVALLDCAHDSTK------ 593
           V +L  P H  L       I N+A        +R+ G I +LV LL  AH  T+      
Sbjct: 495 VKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMG 554

Query: 594 -PAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPV 652
              Q  +   R  E+      AL   ++   N+  IR    IPL  +LL +  EN+    
Sbjct: 555 GTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVA 614

Query: 653 VGTLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDK 704
            G L E A ++    AI+AE     L + L+S NE +  + A  +++ +EDK
Sbjct: 615 AGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSEDK 666



 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 105/458 (22%), Positives = 193/458 (42%), Gaps = 45/458 (9%)

Query: 598  SLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQ 657
            ++    DVE ARC A  L + S       AI K+GGIP L ++L +  +++L   + TL 
Sbjct: 201  TMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLH 260

Query: 658  E-CASEENYRAAIKAERIIENLVKNLNSENEQ---LQEHCAMAIYQCAEDKETRDLVRLH 713
                 +E  + A++    ++ +V  LN  N +   +   C   +     ++E++ ++   
Sbjct: 261  NLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQIL--AYGNQESKLIILAS 318

Query: 714  GGLKPLASLLNNTDNKERLAAVTGAIWK-CSISKENVTKFREYKAIETLVGLLTDQPEEV 772
            GG + L +++  T   E+L   T  + K  S+   N     E   ++ L   LTD  + +
Sbjct: 319  GGPQALVNIM-RTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRL 377

Query: 773  LVNVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVN-VTKAVGACA----VE 827
            + N +  L      R       K  G++ L+  LV +  +  +N VT A G  +      
Sbjct: 378  VQNCLWTL------RNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNN 431

Query: 828  PESMMIIDRLDGVRLL--WSLLKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFVG---G 882
             ++ M++ ++ G+  L    L      D+   A  AL       ++A EM ++ V    G
Sbjct: 432  YKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEA-EMAQNAVRLHYG 490

Query: 883  LELIVNLLKSDNK-EVLASVCAAITNIAKDQENLAVITDHGVVPLLSKLANTNNNKLRHH 941
            L ++V LL   +   ++ +    I N+A    N A + + G +P L +L       +R H
Sbjct: 491  LPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL------VRAH 544

Query: 942  LAEAISRCCMWGRNRVAFGEHKAVAPLVRYLKSNDTNVHRATAQALYQLSEDADNCITMH 1001
              +   R    G  +  F E   +  +V                AL+ L+ D  N I + 
Sbjct: 545  --QDTQRRTSMGGTQQQFVEGVRMEEIV-----------EGCTGALHILARDVHNRIVIR 591

Query: 1002 ENGAVKLLLDMVGSPDQDLQEAAAGCISNIRRLALATE 1039
                + L + ++ SP +++Q  AAG +  + +   A E
Sbjct: 592  GLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAE 629



 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 117/537 (21%), Positives = 208/537 (38%), Gaps = 101/537 (18%)

Query: 454 IQKLVKYLKGGNQTATVIALCSMRDFSLAQETCQLAIRDVGGLEVLINLLE-TDEVKCKI 512
           I +L K L   +Q     A   +   S  + +    +R    +  ++  ++ T++V+   
Sbjct: 153 IPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETAR 212

Query: 513 GSLKILKEISHNPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVAKFKR-ARRV 571
            +   L  +SH+ +    I   GG+P +V +L SP  S+   A  T+ N+   +  A+  
Sbjct: 213 CTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMA 272

Query: 572 VRQHGGITKLVALLDCAH--------DSTKPAQSSLYEARDVEVARCGALALWSCSKSHT 623
           VR  GG+ K+VALL+  +        D  +       E++ + +A  G  AL +  +++T
Sbjct: 273 VRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYT 332

Query: 624 --------------------NKEAIRKAGGIPLLA--------RLLK------------- 642
                               NK AI +AGG+  L         RL++             
Sbjct: 333 YEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAA 392

Query: 643 TSHENMLIPVVGTLQECASEENYRAAIKAERIIENLVKN--------------------- 681
           T  E M   ++GTL +    ++      A  I+ NL  N                     
Sbjct: 393 TKQEGM-EGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTV 451

Query: 682 -LNSENEQLQEHCAMAIYQCA----EDKETRDLVRLHGGLKPLASLLNNTDNKERLAAVT 736
               + E + E    A+        E +  ++ VRLH GL  +  LL+   +   + A  
Sbjct: 452 LRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATV 511

Query: 737 GAIWKCSISKENVTKFREYKAIETLVGLLTDQPEEVLVNVVGALGECCQERENRVIVRKC 796
           G I   ++   N    RE  AI  LV LL                   Q+ + R      
Sbjct: 512 GLIRNLALCPANHAPLREQGAIPRLVQLLV---------------RAHQDTQRRT---SM 553

Query: 797 GGIQPLVNLLVGIN-QALLVNVTKAVGACAVEPESMMIIDRLDGVRLLWSLLKNPHPDVK 855
           GG Q     + G+  + ++   T A+   A +  + ++I  L+ + L   LL +P  +++
Sbjct: 554 GGTQQ--QFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQ 611

Query: 856 ASAAWALCPCIKNAKDAGEMVRSFVGGLELIVNLLKSDNKEVLASVCAAITNIAKDQ 912
             AA  LC   ++ K+A E + +  G    +  LL S N+ V     A +  +++D+
Sbjct: 612 RVAAGVLCELAQD-KEAAEAIEA-EGATAPLTELLHSRNEGVATYAAAVLFRMSEDK 666


>gi|11034811 catenin (cadherin-associated protein), delta 2 (neural
           plakophilin-related arm-repeat protein) [Homo sapiens]
          Length = 1225

 Score = 57.8 bits (138), Expect = 5e-08
 Identities = 97/437 (22%), Positives = 176/437 (40%), Gaps = 78/437 (17%)

Query: 537 LPIMVNILDSPHKSLKCLAAETIANVA-KFKRARRVVRQHGGITKLVALLDCAHDSTKPA 595
           LP ++ +L     S++  AA  + ++     + +  +R+ GGI  LV LLD         
Sbjct: 552 LPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGIQLLVDLLD--------- 602

Query: 596 QSSLYEARDVEVARCGALALWSCSKSHT-NKEAIRKAGGIPLLARLL-KTSHENMLIPVV 653
               +   +V  + CGAL      K++  NK A++  GGIP L RLL KT+   +   V 
Sbjct: 603 ----HRMTEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDLEIRELVT 658

Query: 654 GTLQECASEENYRAAI--KAERIIEN--LVKNLNSENEQLQEHCAMAIYQCAEDKETRDL 709
           G L   +S +  +  I   A  ++ N  ++ +   EN  LQ+   + ++       ++ L
Sbjct: 659 GVLWNLSSCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQLHS------SQVL 712

Query: 710 VRLHGGLKPLASLLNNTDNKER---------LAAVTGAIWKCSISKENV----------- 749
               G L+ ++S       + R         L  +  A+    I  + V           
Sbjct: 713 RNATGCLRNVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCVCILRNLS 772

Query: 750 ------TKFREYKAIETLVGLLTDQPEEVLVNVVGALGECCQERENRVIVRKCGGIQPLV 803
                 T   ++   + L GLL  +         G  G+  ++++++    +  G+ PL 
Sbjct: 773 YRLAAETSQGQHMGTDELDGLLCGEANGKDAESSGCWGKKKKKKKSQ---DQWDGVGPLP 829

Query: 804 NLLVGINQALLVNVTKAVGACAVEPESMMIIDRLDGVRLLWSLLKN-PHPDVKASAAWAL 862
           +                   CA  P+ + ++     V+   +LL    +PD    AA AL
Sbjct: 830 D-------------------CAEPPKGIQMLWHPSIVKPYLTLLSECSNPDTLEGAAGAL 870

Query: 863 CPCIKNAKDAGEMVRSFVG---GLELIVNLLKSDNKEVLASVCAAITNIAKDQENLAVIT 919
                 +      +R+ V    GL ++V LL+ DN  V+ +V  A+ N+A D  N  +I 
Sbjct: 871 QNLAAGSWKWSVYIRAAVRKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIG 930

Query: 920 DHGVVPLLSKLANTNNN 936
            + +  L+ +L   NN+
Sbjct: 931 KYAMRDLVHRLPGGNNS 947



 Score = 38.1 bits (87), Expect = 0.044
 Identities = 30/99 (30%), Positives = 51/99 (51%), Gaps = 7/99 (7%)

Query: 846 LLKNPHPDVKASAAWALCP-CIKNAKDAGEMVRSFVGGLELIVNLLKSDNKEVLASVCAA 904
           +L++  P V+++AA  L   C  + K   E+ R   GG++L+V+LL     EV  S C A
Sbjct: 558 MLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQ--GGIQLLVDLLDHRMTEVHRSACGA 615

Query: 905 ITNI----AKDQENLAVITDHGVVPLLSKLANTNNNKLR 939
           + N+    A D   +A+    G+  L+  L  T + ++R
Sbjct: 616 LRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDLEIR 654



 Score = 36.2 bits (82), Expect = 0.17
 Identities = 30/108 (27%), Positives = 53/108 (49%), Gaps = 4/108 (3%)

Query: 536 GLPIMVNILDSPHKSLKCLAAETIANVAKFKRARRVVRQHGGITKLVALLDCAHDSTKPA 595
           GLPI+V +L   +  + C  A  + N+A   R + ++ ++  +  LV  L   ++S   A
Sbjct: 893 GLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIGKY-AMRDLVHRLPGGNNSNNTA 951

Query: 596 QSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKT 643
             ++ +  D   A C  L     +K+  N +A+R AGGI  L  + K+
Sbjct: 952 SKAMSD--DTVTAVCCTLH-EVITKNMENAKALRDAGGIEKLVGISKS 996



 Score = 32.3 bits (72), Expect = 2.4
 Identities = 48/187 (25%), Positives = 75/187 (40%), Gaps = 49/187 (26%)

Query: 625  KEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECASEENYRAAIKAERIIENLVKNLNS 684
            + A+RK  G+P+L  LL+  ++ ++  V   L+  A                     L+ 
Sbjct: 885  RAAVRKEKGLPILVELLRIDNDRVVCAVATALRNMA---------------------LDV 923

Query: 685  ENEQLQEHCAMAIYQCAEDKETRDLV-RLHGGLKPLASLLNNTDNKERLAAVTGAIWKCS 743
             N++L    AM           RDLV RL GG     +  NNT +K        A+  C+
Sbjct: 924  RNKELIGKYAM-----------RDLVHRLPGG-----NNSNNTASKAMSDDTVTAVC-CT 966

Query: 744  I------SKENVTKFREYKAIETLVGLLTDQPEEVLVNVVGA----LGECCQERENRVIV 793
            +      + EN    R+   IE LVG+   + ++    VV A    L    Q R+ R + 
Sbjct: 967  LHEVITKNMENAKALRDAGGIEKLVGISKSKGDKHSPKVVKAASQVLNSMWQYRDLRSLY 1026

Query: 794  RKCGGIQ 800
            +K G  Q
Sbjct: 1027 KKDGWSQ 1033


>gi|4504897 karyopherin alpha 2 [Homo sapiens]
          Length = 529

 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 66/284 (23%), Positives = 113/284 (39%), Gaps = 13/284 (4%)

Query: 675 IENLVKNLNSENEQLQEHCAMAIYQCAEDKET-RDLVRLHGGLKPLASLLNNTDNKERLA 733
           I   +  L S +  + E    A+   A D    RDLV  +G + PL +LL   D      
Sbjct: 164 IPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAVPDMSSLAC 223

Query: 734 A-VTGAIWKCSISKENVTKFREYKAIE----TLVGLLTDQPEEVLVNVVGALGECCQERE 788
             +    W  S    N        A+E    TLV LL     EVL +   A+        
Sbjct: 224 GYLRNLTWTLSNLCRNKNPAPPIDAVEQILPTLVRLLHHDDPEVLADTCWAISYLTDGPN 283

Query: 789 NRV-IVRKCGGIQPLVNLLVGINQALLVNVTKAVG--ACAVEPESMMIIDRLDGVRLLWS 845
            R+ +V K G +  LV LL      ++    +A+G      + ++ ++ID    + +  S
Sbjct: 284 ERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIVTGTDEQTQVVIDA-GALAVFPS 342

Query: 846 LLKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFVGGLELIVNLLKSDNKEVLASVCAAI 905
           LL NP  +++  A W +       +D  + V +  G +  +V++L   + +       A+
Sbjct: 343 LLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNH-GLVPFLVSVLSKADFKTQKEAVWAV 401

Query: 906 TNIAK--DQENLAVITDHGVVPLLSKLANTNNNKLRHHLAEAIS 947
           TN       E +  +   G++  L  L    + K+   + +AIS
Sbjct: 402 TNYTSGGTVEQIVYLVHCGIIEPLMNLLTAKDTKIILVILDAIS 445



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 69/305 (22%), Positives = 121/305 (39%), Gaps = 32/305 (10%)

Query: 531 IVDLGGLPIMVNILDSPHKSLKCLAAETIANVAKFKRA-RRVVRQHGGITKLVALLDCAH 589
           +VD G +P  +++L SPH  +   A   + N+A      R +V ++G +  L+ALL    
Sbjct: 158 VVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALL---- 213

Query: 590 DSTKPAQSSLYEARDVEVARCGAL--ALWSCSKSHTNK------EAIRKAGGIPLLARLL 641
               P  SSL          CG L    W+ S    NK      +A+ +   +P L RLL
Sbjct: 214 --AVPDMSSL---------ACGYLRNLTWTLSNLCRNKNPAPPIDAVEQI--LPTLVRLL 260

Query: 642 KTSHENMLIPVVGTLQECASEENYRAAIKAER-IIENLVKNLNSENEQLQEHCAMAI--Y 698
                 +L      +       N R  +  +  ++  LVK L +    +      AI   
Sbjct: 261 HHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNI 320

Query: 699 QCAEDKETRDLVRLHGGLKPLASLLNNTDNKERLAAVTGAIWKCSISKENVTKFREYKAI 758
               D++T+ ++   G L    SLL N     +  A        +  ++ + +   +  +
Sbjct: 321 VTGTDEQTQVVIDA-GALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLV 379

Query: 759 ETLVGLLTDQPEEVLVNVVGALGECCQ--ERENRVIVRKCGGIQPLVNLLVGINQALLVN 816
             LV +L+    +     V A+         E  V +  CG I+PL+NLL   +  +++ 
Sbjct: 380 PFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNLLTAKDTKIILV 439

Query: 817 VTKAV 821
           +  A+
Sbjct: 440 ILDAI 444



 Score = 36.6 bits (83), Expect = 0.13
 Identities = 44/200 (22%), Positives = 83/200 (41%), Gaps = 19/200 (9%)

Query: 845  SLLKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFV---GGLELIVNLLKSDNKEVLASV 901
            SLL +PH  +   A WAL     N    G + R  V   G ++ ++ LL   +   LA  
Sbjct: 169  SLLASPHAHISEQAVWAL----GNIAGDGSVFRDLVIKYGAVDPLLALLAVPDMSSLA-- 222

Query: 902  CAAITNIAKDQENLA--------VITDHGVVPLLSKLANTNNNKLRHHLAEAISRCCMWG 953
            C  + N+     NL         +     ++P L +L + ++ ++      AIS      
Sbjct: 223  CGYLRNLTWTLSNLCRNKNPAPPIDAVEQILPTLVRLLHHDDPEVLADTCWAISYLTDGP 282

Query: 954  RNRVAFGEHKAVAP-LVRYLKSNDTNVHRATAQALYQLSEDAD-NCITMHENGAVKLLLD 1011
              R+       V P LV+ L +++  +     +A+  +    D     + + GA+ +   
Sbjct: 283  NERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPS 342

Query: 1012 MVGSPDQDLQEAAAGCISNI 1031
            ++ +P  ++Q+ A   +SNI
Sbjct: 343  LLTNPKTNIQKEATWTMSNI 362


>gi|4502247 armadillo repeat protein [Homo sapiens]
          Length = 962

 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 44/135 (32%), Positives = 66/135 (48%), Gaps = 15/135 (11%)

Query: 537 LPIMVNILDSPHKSLKCLAAETIANVA-KFKRARRVVRQHGGITKLVALLDCAHDSTKPA 595
           LP ++ +L  P   +K  AA  + ++  + +  +R VRQ  G+  LVALLD         
Sbjct: 360 LPEVLAMLRHPVDPVKANAAAYLQHLCFENEGVKRRVRQLRGLPLLVALLD--------- 410

Query: 596 QSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVV-G 654
               +   +V    CGAL   S  +   NK AIR  GG+P L RLL+ + +N +  +V G
Sbjct: 411 ----HPRAEVRRRACGALRNLSYGRDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTG 466

Query: 655 TLQECASEENYRAAI 669
           TL   +S E  +  I
Sbjct: 467 TLWNLSSYEPLKMVI 481



 Score = 38.5 bits (88), Expect = 0.033
 Identities = 47/183 (25%), Positives = 70/183 (38%), Gaps = 35/183 (19%)

Query: 751 KFREYKAIETLVGLLTDQPEEVLVNVVGALGECCQERE--NRVIVRKCGGIQPLVNLLVG 808
           + R+ + +  LV LL     EV     GAL      R+  N+  +R CGG+  LV LL  
Sbjct: 395 RVRQLRGLPLLVALLDHPRAEVRRRACGALRNLSYGRDTDNKAAIRDCGGVPALVRLLRA 454

Query: 809 I--NQALLVNVTKAVGACAVEPESMMIIDRLDGVRLL----------WSLLKNPHPDVK- 855
              N+   +         + EP  M+IID   G++ L          W   + P+ D K 
Sbjct: 455 ARDNEVRELVTGTLWNLSSYEPLKMVIIDH--GLQTLTHEVIVPHSGWE--REPNEDSKP 510

Query: 856 ASAAWA-----LCPCIKNAKDAGE-----------MVRSFVGGLELIVNLLKSDNKEVLA 899
             A W         C++N    G            +V + +  L+  V    +DNK V  
Sbjct: 511 RDAEWTTVFKNTSGCLRNVSSDGAEARRRLRECEGLVDALLHALQSAVGRKDTDNKSVEN 570

Query: 900 SVC 902
            VC
Sbjct: 571 CVC 573



 Score = 37.4 bits (85), Expect = 0.075
 Identities = 20/70 (28%), Positives = 37/70 (52%), Gaps = 2/70 (2%)

Query: 524 NPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVAKFKRA--RRVVRQHGGITKL 581
           N  +++ +  L GLP++V +LD P   ++  A   + N++  +    +  +R  GG+  L
Sbjct: 389 NEGVKRRVRQLRGLPLLVALLDHPRAEVRRRACGALRNLSYGRDTDNKAAIRDCGGVPAL 448

Query: 582 VALLDCAHDS 591
           V LL  A D+
Sbjct: 449 VRLLRAARDN 458


>gi|146231975 catenin, delta 1 isoform 3A [Homo sapiens]
          Length = 832

 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 100/429 (23%), Positives = 174/429 (40%), Gaps = 66/429 (15%)

Query: 537 LPIMVNILDSPHKSLKCLAAETIANVA-KFKRARRVVRQHGGITKLVALLDCAHDSTKPA 595
           LP ++ +L     ++K  AA  + ++  +  + +  VR+  GI  LV LLD         
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLD--------- 317

Query: 596 QSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVV-G 654
               +  ++V +  CGAL   S  +   NK AI+   G+P L RLL+ + +  L  V+ G
Sbjct: 318 ----HPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITG 373

Query: 655 TLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKETRD------ 708
           TL   +S +    +IK E I+++ +  L   +E +  H      +  ED + R       
Sbjct: 374 TLWNLSSHD----SIKME-IVDHALHALT--DEVIIPHSGWE-REPNEDCKPRHIEWESV 425

Query: 709 LVRLHGGLKPLASLLNNTDNKERLAAVTGAIWKC--SISKENVTKFREYKAIETLVGLLT 766
           L    G L+ ++S    ++ + +L    G +      +  E   K  + K +E  V LL 
Sbjct: 426 LTNTAGCLRNVSS--ERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLR 483

Query: 767 DQPEEVLVNVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAV 826
           +   +V   +  A  E  QE              P V    G + A      K  G   +
Sbjct: 484 NLSYQVHREIPQA--ERYQE------------AAPNVANNTGPHAASCFGAKKGKGKKPI 529

Query: 827 EPESMMIID---------------RLDGVRLLWSLLK-NPHPDVKASAAWALCPCIKNAK 870
           E  +   +D               + + VR+  SLLK +  P +  ++A A+        
Sbjct: 530 EDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRW 589

Query: 871 DAGEMVRSFV---GGLELIVNLLKSDNKEVLASVCAAITNIAKDQENLAVITDHGVVPLL 927
             G  +RS +     L  I +LL ++++ V+ +   A+ N+A D  N  +I  H +  L+
Sbjct: 590 TYGRYIRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLV 649

Query: 928 SKLANTNNN 936
             L     N
Sbjct: 650 KNLPGGQQN 658



 Score = 35.8 bits (81), Expect = 0.22
 Identities = 35/170 (20%), Positives = 77/170 (45%), Gaps = 28/170 (16%)

Query: 524 NPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVA--KFKRARRVVRQHGGITKL 581
           N +++ ++  L G+P++V +LD P K +   A   + N++  + +  +  ++   G+  L
Sbjct: 296 NDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPAL 355

Query: 582 VALLDCAHDSTKPAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLL 641
           V L              L +ARD+++       LW+ S   + K        + ++   L
Sbjct: 356 VRL--------------LRKARDMDLTEVITGTLWNLSSHDSIK--------MEIVDHAL 393

Query: 642 KTSHENMLIPVVGTLQECASEENYRAAIKAERIIEN---LVKNLNSENEQ 688
               + ++IP  G  +E  +E+     I+ E ++ N    ++N++SE  +
Sbjct: 394 HALTDEVIIPHSGWERE-PNEDCKPRHIEWESVLTNTAGCLRNVSSERSE 442



 Score = 32.0 bits (71), Expect = 3.1
 Identities = 33/130 (25%), Positives = 55/130 (42%), Gaps = 16/130 (12%)

Query: 625 KEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECASEENYRAAIKAERIIENLVKNL-- 682
           + A+R+   +  +A LL   HE ++    G L+  A +   +  I  +  I NLVKNL  
Sbjct: 596 RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELI-GKHAIPNLVKNLPG 654

Query: 683 --NSENEQLQEHCAMAIYQ-----CAEDKETRDLVRLHGGLKPLASLLNNTDNKER---- 731
              + +    E   ++I        AE+ E    +R   G++ L  L+N + N+      
Sbjct: 655 GQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLV-LINKSGNRSEKEVR 713

Query: 732 -LAAVTGAIW 740
             A V   IW
Sbjct: 714 AAALVLQTIW 723



 Score = 30.8 bits (68), Expect = 7.0
 Identities = 31/128 (24%), Positives = 53/128 (41%), Gaps = 6/128 (4%)

Query: 721 SLLNNTDNKERLAAVTGAIWKCSISKENVTKF-----REYKAIETLVGLLTDQPEEVLVN 775
           SLL  +     L A  GAI      +    ++     R+ KA+  +  LLT++ E V+  
Sbjct: 563 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKA 622

Query: 776 VVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAVEPESMMIID 835
             GAL     +  N+ ++ K   I  LV  L G  Q    N ++      +   + +I +
Sbjct: 623 ASGALRNLAVDARNKELIGK-HAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 681

Query: 836 RLDGVRLL 843
            L+  + L
Sbjct: 682 NLEAAKKL 689


>gi|146231948 catenin, delta 1 isoform 3A [Homo sapiens]
          Length = 832

 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 100/429 (23%), Positives = 174/429 (40%), Gaps = 66/429 (15%)

Query: 537 LPIMVNILDSPHKSLKCLAAETIANVA-KFKRARRVVRQHGGITKLVALLDCAHDSTKPA 595
           LP ++ +L     ++K  AA  + ++  +  + +  VR+  GI  LV LLD         
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLD--------- 317

Query: 596 QSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVV-G 654
               +  ++V +  CGAL   S  +   NK AI+   G+P L RLL+ + +  L  V+ G
Sbjct: 318 ----HPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITG 373

Query: 655 TLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKETRD------ 708
           TL   +S +    +IK E I+++ +  L   +E +  H      +  ED + R       
Sbjct: 374 TLWNLSSHD----SIKME-IVDHALHALT--DEVIIPHSGWE-REPNEDCKPRHIEWESV 425

Query: 709 LVRLHGGLKPLASLLNNTDNKERLAAVTGAIWKC--SISKENVTKFREYKAIETLVGLLT 766
           L    G L+ ++S    ++ + +L    G +      +  E   K  + K +E  V LL 
Sbjct: 426 LTNTAGCLRNVSS--ERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLR 483

Query: 767 DQPEEVLVNVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAV 826
           +   +V   +  A  E  QE              P V    G + A      K  G   +
Sbjct: 484 NLSYQVHREIPQA--ERYQE------------AAPNVANNTGPHAASCFGAKKGKGKKPI 529

Query: 827 EPESMMIID---------------RLDGVRLLWSLLK-NPHPDVKASAAWALCPCIKNAK 870
           E  +   +D               + + VR+  SLLK +  P +  ++A A+        
Sbjct: 530 EDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRW 589

Query: 871 DAGEMVRSFV---GGLELIVNLLKSDNKEVLASVCAAITNIAKDQENLAVITDHGVVPLL 927
             G  +RS +     L  I +LL ++++ V+ +   A+ N+A D  N  +I  H +  L+
Sbjct: 590 TYGRYIRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLV 649

Query: 928 SKLANTNNN 936
             L     N
Sbjct: 650 KNLPGGQQN 658



 Score = 35.8 bits (81), Expect = 0.22
 Identities = 35/170 (20%), Positives = 77/170 (45%), Gaps = 28/170 (16%)

Query: 524 NPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVA--KFKRARRVVRQHGGITKL 581
           N +++ ++  L G+P++V +LD P K +   A   + N++  + +  +  ++   G+  L
Sbjct: 296 NDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPAL 355

Query: 582 VALLDCAHDSTKPAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLL 641
           V L              L +ARD+++       LW+ S   + K        + ++   L
Sbjct: 356 VRL--------------LRKARDMDLTEVITGTLWNLSSHDSIK--------MEIVDHAL 393

Query: 642 KTSHENMLIPVVGTLQECASEENYRAAIKAERIIEN---LVKNLNSENEQ 688
               + ++IP  G  +E  +E+     I+ E ++ N    ++N++SE  +
Sbjct: 394 HALTDEVIIPHSGWERE-PNEDCKPRHIEWESVLTNTAGCLRNVSSERSE 442



 Score = 32.0 bits (71), Expect = 3.1
 Identities = 33/130 (25%), Positives = 55/130 (42%), Gaps = 16/130 (12%)

Query: 625 KEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECASEENYRAAIKAERIIENLVKNL-- 682
           + A+R+   +  +A LL   HE ++    G L+  A +   +  I  +  I NLVKNL  
Sbjct: 596 RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELI-GKHAIPNLVKNLPG 654

Query: 683 --NSENEQLQEHCAMAIYQ-----CAEDKETRDLVRLHGGLKPLASLLNNTDNKER---- 731
              + +    E   ++I        AE+ E    +R   G++ L  L+N + N+      
Sbjct: 655 GQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLV-LINKSGNRSEKEVR 713

Query: 732 -LAAVTGAIW 740
             A V   IW
Sbjct: 714 AAALVLQTIW 723



 Score = 30.8 bits (68), Expect = 7.0
 Identities = 31/128 (24%), Positives = 53/128 (41%), Gaps = 6/128 (4%)

Query: 721 SLLNNTDNKERLAAVTGAIWKCSISKENVTKF-----REYKAIETLVGLLTDQPEEVLVN 775
           SLL  +     L A  GAI      +    ++     R+ KA+  +  LLT++ E V+  
Sbjct: 563 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKA 622

Query: 776 VVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAVEPESMMIID 835
             GAL     +  N+ ++ K   I  LV  L G  Q    N ++      +   + +I +
Sbjct: 623 ASGALRNLAVDARNKELIGK-HAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 681

Query: 836 RLDGVRLL 843
            L+  + L
Sbjct: 682 NLEAAKKL 689


>gi|146231994 catenin, delta 1 isoform 3A [Homo sapiens]
          Length = 832

 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 100/429 (23%), Positives = 174/429 (40%), Gaps = 66/429 (15%)

Query: 537 LPIMVNILDSPHKSLKCLAAETIANVA-KFKRARRVVRQHGGITKLVALLDCAHDSTKPA 595
           LP ++ +L     ++K  AA  + ++  +  + +  VR+  GI  LV LLD         
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLD--------- 317

Query: 596 QSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVV-G 654
               +  ++V +  CGAL   S  +   NK AI+   G+P L RLL+ + +  L  V+ G
Sbjct: 318 ----HPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITG 373

Query: 655 TLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKETRD------ 708
           TL   +S +    +IK E I+++ +  L   +E +  H      +  ED + R       
Sbjct: 374 TLWNLSSHD----SIKME-IVDHALHALT--DEVIIPHSGWE-REPNEDCKPRHIEWESV 425

Query: 709 LVRLHGGLKPLASLLNNTDNKERLAAVTGAIWKC--SISKENVTKFREYKAIETLVGLLT 766
           L    G L+ ++S    ++ + +L    G +      +  E   K  + K +E  V LL 
Sbjct: 426 LTNTAGCLRNVSS--ERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLR 483

Query: 767 DQPEEVLVNVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAV 826
           +   +V   +  A  E  QE              P V    G + A      K  G   +
Sbjct: 484 NLSYQVHREIPQA--ERYQE------------AAPNVANNTGPHAASCFGAKKGKGKKPI 529

Query: 827 EPESMMIID---------------RLDGVRLLWSLLK-NPHPDVKASAAWALCPCIKNAK 870
           E  +   +D               + + VR+  SLLK +  P +  ++A A+        
Sbjct: 530 EDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRW 589

Query: 871 DAGEMVRSFV---GGLELIVNLLKSDNKEVLASVCAAITNIAKDQENLAVITDHGVVPLL 927
             G  +RS +     L  I +LL ++++ V+ +   A+ N+A D  N  +I  H +  L+
Sbjct: 590 TYGRYIRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLV 649

Query: 928 SKLANTNNN 936
             L     N
Sbjct: 650 KNLPGGQQN 658



 Score = 35.8 bits (81), Expect = 0.22
 Identities = 35/170 (20%), Positives = 77/170 (45%), Gaps = 28/170 (16%)

Query: 524 NPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVA--KFKRARRVVRQHGGITKL 581
           N +++ ++  L G+P++V +LD P K +   A   + N++  + +  +  ++   G+  L
Sbjct: 296 NDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPAL 355

Query: 582 VALLDCAHDSTKPAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLL 641
           V L              L +ARD+++       LW+ S   + K        + ++   L
Sbjct: 356 VRL--------------LRKARDMDLTEVITGTLWNLSSHDSIK--------MEIVDHAL 393

Query: 642 KTSHENMLIPVVGTLQECASEENYRAAIKAERIIEN---LVKNLNSENEQ 688
               + ++IP  G  +E  +E+     I+ E ++ N    ++N++SE  +
Sbjct: 394 HALTDEVIIPHSGWERE-PNEDCKPRHIEWESVLTNTAGCLRNVSSERSE 442



 Score = 32.0 bits (71), Expect = 3.1
 Identities = 33/130 (25%), Positives = 55/130 (42%), Gaps = 16/130 (12%)

Query: 625 KEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECASEENYRAAIKAERIIENLVKNL-- 682
           + A+R+   +  +A LL   HE ++    G L+  A +   +  I  +  I NLVKNL  
Sbjct: 596 RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELI-GKHAIPNLVKNLPG 654

Query: 683 --NSENEQLQEHCAMAIYQ-----CAEDKETRDLVRLHGGLKPLASLLNNTDNKER---- 731
              + +    E   ++I        AE+ E    +R   G++ L  L+N + N+      
Sbjct: 655 GQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLV-LINKSGNRSEKEVR 713

Query: 732 -LAAVTGAIW 740
             A V   IW
Sbjct: 714 AAALVLQTIW 723



 Score = 30.8 bits (68), Expect = 7.0
 Identities = 31/128 (24%), Positives = 53/128 (41%), Gaps = 6/128 (4%)

Query: 721 SLLNNTDNKERLAAVTGAIWKCSISKENVTKF-----REYKAIETLVGLLTDQPEEVLVN 775
           SLL  +     L A  GAI      +    ++     R+ KA+  +  LLT++ E V+  
Sbjct: 563 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKA 622

Query: 776 VVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAVEPESMMIID 835
             GAL     +  N+ ++ K   I  LV  L G  Q    N ++      +   + +I +
Sbjct: 623 ASGALRNLAVDARNKELIGK-HAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 681

Query: 836 RLDGVRLL 843
            L+  + L
Sbjct: 682 NLEAAKKL 689


>gi|146231946 catenin, delta 1 isoform 3B [Homo sapiens]
          Length = 840

 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 100/429 (23%), Positives = 174/429 (40%), Gaps = 66/429 (15%)

Query: 537 LPIMVNILDSPHKSLKCLAAETIANVA-KFKRARRVVRQHGGITKLVALLDCAHDSTKPA 595
           LP ++ +L     ++K  AA  + ++  +  + +  VR+  GI  LV LLD         
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLD--------- 317

Query: 596 QSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVV-G 654
               +  ++V +  CGAL   S  +   NK AI+   G+P L RLL+ + +  L  V+ G
Sbjct: 318 ----HPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITG 373

Query: 655 TLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKETRD------ 708
           TL   +S +    +IK E I+++ +  L   +E +  H      +  ED + R       
Sbjct: 374 TLWNLSSHD----SIKME-IVDHALHALT--DEVIIPHSGWE-REPNEDCKPRHIEWESV 425

Query: 709 LVRLHGGLKPLASLLNNTDNKERLAAVTGAIWKC--SISKENVTKFREYKAIETLVGLLT 766
           L    G L+ ++S    ++ + +L    G +      +  E   K  + K +E  V LL 
Sbjct: 426 LTNTAGCLRNVSS--ERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLR 483

Query: 767 DQPEEVLVNVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAV 826
           +   +V   +  A  E  QE              P V    G + A      K  G   +
Sbjct: 484 NLSYQVHREIPQA--ERYQE------------AAPNVANNTGPHAASCFGAKKGKGKKPI 529

Query: 827 EPESMMIID---------------RLDGVRLLWSLLK-NPHPDVKASAAWALCPCIKNAK 870
           E  +   +D               + + VR+  SLLK +  P +  ++A A+        
Sbjct: 530 EDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRW 589

Query: 871 DAGEMVRSFV---GGLELIVNLLKSDNKEVLASVCAAITNIAKDQENLAVITDHGVVPLL 927
             G  +RS +     L  I +LL ++++ V+ +   A+ N+A D  N  +I  H +  L+
Sbjct: 590 TYGRYIRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLV 649

Query: 928 SKLANTNNN 936
             L     N
Sbjct: 650 KNLPGGQQN 658



 Score = 35.8 bits (81), Expect = 0.22
 Identities = 35/170 (20%), Positives = 77/170 (45%), Gaps = 28/170 (16%)

Query: 524 NPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVA--KFKRARRVVRQHGGITKL 581
           N +++ ++  L G+P++V +LD P K +   A   + N++  + +  +  ++   G+  L
Sbjct: 296 NDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPAL 355

Query: 582 VALLDCAHDSTKPAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLL 641
           V L              L +ARD+++       LW+ S   + K        + ++   L
Sbjct: 356 VRL--------------LRKARDMDLTEVITGTLWNLSSHDSIK--------MEIVDHAL 393

Query: 642 KTSHENMLIPVVGTLQECASEENYRAAIKAERIIEN---LVKNLNSENEQ 688
               + ++IP  G  +E  +E+     I+ E ++ N    ++N++SE  +
Sbjct: 394 HALTDEVIIPHSGWERE-PNEDCKPRHIEWESVLTNTAGCLRNVSSERSE 442



 Score = 32.0 bits (71), Expect = 3.1
 Identities = 33/130 (25%), Positives = 55/130 (42%), Gaps = 16/130 (12%)

Query: 625 KEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECASEENYRAAIKAERIIENLVKNL-- 682
           + A+R+   +  +A LL   HE ++    G L+  A +   +  I  +  I NLVKNL  
Sbjct: 596 RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELI-GKHAIPNLVKNLPG 654

Query: 683 --NSENEQLQEHCAMAIYQ-----CAEDKETRDLVRLHGGLKPLASLLNNTDNKER---- 731
              + +    E   ++I        AE+ E    +R   G++ L  L+N + N+      
Sbjct: 655 GQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLV-LINKSGNRSEKEVR 713

Query: 732 -LAAVTGAIW 740
             A V   IW
Sbjct: 714 AAALVLQTIW 723



 Score = 30.8 bits (68), Expect = 7.0
 Identities = 31/128 (24%), Positives = 53/128 (41%), Gaps = 6/128 (4%)

Query: 721 SLLNNTDNKERLAAVTGAIWKCSISKENVTKF-----REYKAIETLVGLLTDQPEEVLVN 775
           SLL  +     L A  GAI      +    ++     R+ KA+  +  LLT++ E V+  
Sbjct: 563 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKA 622

Query: 776 VVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAVEPESMMIID 835
             GAL     +  N+ ++ K   I  LV  L G  Q    N ++      +   + +I +
Sbjct: 623 ASGALRNLAVDARNKELIGK-HAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 681

Query: 836 RLDGVRLL 843
            L+  + L
Sbjct: 682 NLEAAKKL 689


>gi|146231991 catenin, delta 1 isoform 3AB [Homo sapiens]
          Length = 861

 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 100/429 (23%), Positives = 174/429 (40%), Gaps = 66/429 (15%)

Query: 537 LPIMVNILDSPHKSLKCLAAETIANVA-KFKRARRVVRQHGGITKLVALLDCAHDSTKPA 595
           LP ++ +L     ++K  AA  + ++  +  + +  VR+  GI  LV LLD         
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLD--------- 317

Query: 596 QSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVV-G 654
               +  ++V +  CGAL   S  +   NK AI+   G+P L RLL+ + +  L  V+ G
Sbjct: 318 ----HPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITG 373

Query: 655 TLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKETRD------ 708
           TL   +S +    +IK E I+++ +  L   +E +  H      +  ED + R       
Sbjct: 374 TLWNLSSHD----SIKME-IVDHALHALT--DEVIIPHSGWE-REPNEDCKPRHIEWESV 425

Query: 709 LVRLHGGLKPLASLLNNTDNKERLAAVTGAIWKC--SISKENVTKFREYKAIETLVGLLT 766
           L    G L+ ++S    ++ + +L    G +      +  E   K  + K +E  V LL 
Sbjct: 426 LTNTAGCLRNVSS--ERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLR 483

Query: 767 DQPEEVLVNVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAV 826
           +   +V   +  A  E  QE              P V    G + A      K  G   +
Sbjct: 484 NLSYQVHREIPQA--ERYQE------------AAPNVANNTGPHAASCFGAKKGKGKKPI 529

Query: 827 EPESMMIID---------------RLDGVRLLWSLLK-NPHPDVKASAAWALCPCIKNAK 870
           E  +   +D               + + VR+  SLLK +  P +  ++A A+        
Sbjct: 530 EDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRW 589

Query: 871 DAGEMVRSFV---GGLELIVNLLKSDNKEVLASVCAAITNIAKDQENLAVITDHGVVPLL 927
             G  +RS +     L  I +LL ++++ V+ +   A+ N+A D  N  +I  H +  L+
Sbjct: 590 TYGRYIRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLV 649

Query: 928 SKLANTNNN 936
             L     N
Sbjct: 650 KNLPGGQQN 658



 Score = 35.8 bits (81), Expect = 0.22
 Identities = 35/170 (20%), Positives = 77/170 (45%), Gaps = 28/170 (16%)

Query: 524 NPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVA--KFKRARRVVRQHGGITKL 581
           N +++ ++  L G+P++V +LD P K +   A   + N++  + +  +  ++   G+  L
Sbjct: 296 NDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPAL 355

Query: 582 VALLDCAHDSTKPAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLL 641
           V L              L +ARD+++       LW+ S   + K        + ++   L
Sbjct: 356 VRL--------------LRKARDMDLTEVITGTLWNLSSHDSIK--------MEIVDHAL 393

Query: 642 KTSHENMLIPVVGTLQECASEENYRAAIKAERIIEN---LVKNLNSENEQ 688
               + ++IP  G  +E  +E+     I+ E ++ N    ++N++SE  +
Sbjct: 394 HALTDEVIIPHSGWERE-PNEDCKPRHIEWESVLTNTAGCLRNVSSERSE 442



 Score = 32.0 bits (71), Expect = 3.1
 Identities = 33/130 (25%), Positives = 55/130 (42%), Gaps = 16/130 (12%)

Query: 625 KEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECASEENYRAAIKAERIIENLVKNL-- 682
           + A+R+   +  +A LL   HE ++    G L+  A +   +  I  +  I NLVKNL  
Sbjct: 596 RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELI-GKHAIPNLVKNLPG 654

Query: 683 --NSENEQLQEHCAMAIYQ-----CAEDKETRDLVRLHGGLKPLASLLNNTDNKER---- 731
              + +    E   ++I        AE+ E    +R   G++ L  L+N + N+      
Sbjct: 655 GQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLV-LINKSGNRSEKEVR 713

Query: 732 -LAAVTGAIW 740
             A V   IW
Sbjct: 714 AAALVLQTIW 723



 Score = 30.8 bits (68), Expect = 7.0
 Identities = 31/128 (24%), Positives = 53/128 (41%), Gaps = 6/128 (4%)

Query: 721 SLLNNTDNKERLAAVTGAIWKCSISKENVTKF-----REYKAIETLVGLLTDQPEEVLVN 775
           SLL  +     L A  GAI      +    ++     R+ KA+  +  LLT++ E V+  
Sbjct: 563 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKA 622

Query: 776 VVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAVEPESMMIID 835
             GAL     +  N+ ++ K   I  LV  L G  Q    N ++      +   + +I +
Sbjct: 623 ASGALRNLAVDARNKELIGK-HAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 681

Query: 836 RLDGVRLL 843
            L+  + L
Sbjct: 682 NLEAAKKL 689


>gi|146231942 catenin, delta 1 isoform 1A [Homo sapiens]
          Length = 933

 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 100/429 (23%), Positives = 174/429 (40%), Gaps = 66/429 (15%)

Query: 537 LPIMVNILDSPHKSLKCLAAETIANVA-KFKRARRVVRQHGGITKLVALLDCAHDSTKPA 595
           LP ++ +L     ++K  AA  + ++  +  + +  VR+  GI  LV LLD         
Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLD--------- 418

Query: 596 QSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVV-G 654
               +  ++V +  CGAL   S  +   NK AI+   G+P L RLL+ + +  L  V+ G
Sbjct: 419 ----HPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITG 474

Query: 655 TLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKETRD------ 708
           TL   +S +    +IK E I+++ +  L   +E +  H      +  ED + R       
Sbjct: 475 TLWNLSSHD----SIKME-IVDHALHALT--DEVIIPHSGWE-REPNEDCKPRHIEWESV 526

Query: 709 LVRLHGGLKPLASLLNNTDNKERLAAVTGAIWKC--SISKENVTKFREYKAIETLVGLLT 766
           L    G L+ ++S    ++ + +L    G +      +  E   K  + K +E  V LL 
Sbjct: 527 LTNTAGCLRNVSS--ERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLR 584

Query: 767 DQPEEVLVNVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAV 826
           +   +V   +  A  E  QE              P V    G + A      K  G   +
Sbjct: 585 NLSYQVHREIPQA--ERYQE------------AAPNVANNTGPHAASCFGAKKGKGKKPI 630

Query: 827 EPESMMIID---------------RLDGVRLLWSLLK-NPHPDVKASAAWALCPCIKNAK 870
           E  +   +D               + + VR+  SLLK +  P +  ++A A+        
Sbjct: 631 EDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRW 690

Query: 871 DAGEMVRSFV---GGLELIVNLLKSDNKEVLASVCAAITNIAKDQENLAVITDHGVVPLL 927
             G  +RS +     L  I +LL ++++ V+ +   A+ N+A D  N  +I  H +  L+
Sbjct: 691 TYGRYIRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLV 750

Query: 928 SKLANTNNN 936
             L     N
Sbjct: 751 KNLPGGQQN 759



 Score = 35.8 bits (81), Expect = 0.22
 Identities = 35/170 (20%), Positives = 77/170 (45%), Gaps = 28/170 (16%)

Query: 524 NPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVA--KFKRARRVVRQHGGITKL 581
           N +++ ++  L G+P++V +LD P K +   A   + N++  + +  +  ++   G+  L
Sbjct: 397 NDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPAL 456

Query: 582 VALLDCAHDSTKPAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLL 641
           V L              L +ARD+++       LW+ S   + K        + ++   L
Sbjct: 457 VRL--------------LRKARDMDLTEVITGTLWNLSSHDSIK--------MEIVDHAL 494

Query: 642 KTSHENMLIPVVGTLQECASEENYRAAIKAERIIEN---LVKNLNSENEQ 688
               + ++IP  G  +E  +E+     I+ E ++ N    ++N++SE  +
Sbjct: 495 HALTDEVIIPHSGWERE-PNEDCKPRHIEWESVLTNTAGCLRNVSSERSE 543



 Score = 32.0 bits (71), Expect = 3.1
 Identities = 33/130 (25%), Positives = 55/130 (42%), Gaps = 16/130 (12%)

Query: 625 KEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECASEENYRAAIKAERIIENLVKNL-- 682
           + A+R+   +  +A LL   HE ++    G L+  A +   +  I  +  I NLVKNL  
Sbjct: 697 RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELI-GKHAIPNLVKNLPG 755

Query: 683 --NSENEQLQEHCAMAIYQ-----CAEDKETRDLVRLHGGLKPLASLLNNTDNKER---- 731
              + +    E   ++I        AE+ E    +R   G++ L  L+N + N+      
Sbjct: 756 GQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLV-LINKSGNRSEKEVR 814

Query: 732 -LAAVTGAIW 740
             A V   IW
Sbjct: 815 AAALVLQTIW 824



 Score = 30.8 bits (68), Expect = 7.0
 Identities = 31/128 (24%), Positives = 53/128 (41%), Gaps = 6/128 (4%)

Query: 721 SLLNNTDNKERLAAVTGAIWKCSISKENVTKF-----REYKAIETLVGLLTDQPEEVLVN 775
           SLL  +     L A  GAI      +    ++     R+ KA+  +  LLT++ E V+  
Sbjct: 664 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKA 723

Query: 776 VVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAVEPESMMIID 835
             GAL     +  N+ ++ K   I  LV  L G  Q    N ++      +   + +I +
Sbjct: 724 ASGALRNLAVDARNKELIGK-HAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 782

Query: 836 RLDGVRLL 843
            L+  + L
Sbjct: 783 NLEAAKKL 790


>gi|146231968 catenin, delta 1 isoform 1A [Homo sapiens]
          Length = 933

 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 100/429 (23%), Positives = 174/429 (40%), Gaps = 66/429 (15%)

Query: 537 LPIMVNILDSPHKSLKCLAAETIANVA-KFKRARRVVRQHGGITKLVALLDCAHDSTKPA 595
           LP ++ +L     ++K  AA  + ++  +  + +  VR+  GI  LV LLD         
Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLD--------- 418

Query: 596 QSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVV-G 654
               +  ++V +  CGAL   S  +   NK AI+   G+P L RLL+ + +  L  V+ G
Sbjct: 419 ----HPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITG 474

Query: 655 TLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKETRD------ 708
           TL   +S +    +IK E I+++ +  L   +E +  H      +  ED + R       
Sbjct: 475 TLWNLSSHD----SIKME-IVDHALHALT--DEVIIPHSGWE-REPNEDCKPRHIEWESV 526

Query: 709 LVRLHGGLKPLASLLNNTDNKERLAAVTGAIWKC--SISKENVTKFREYKAIETLVGLLT 766
           L    G L+ ++S    ++ + +L    G +      +  E   K  + K +E  V LL 
Sbjct: 527 LTNTAGCLRNVSS--ERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLR 584

Query: 767 DQPEEVLVNVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAV 826
           +   +V   +  A  E  QE              P V    G + A      K  G   +
Sbjct: 585 NLSYQVHREIPQA--ERYQE------------AAPNVANNTGPHAASCFGAKKGKGKKPI 630

Query: 827 EPESMMIID---------------RLDGVRLLWSLLK-NPHPDVKASAAWALCPCIKNAK 870
           E  +   +D               + + VR+  SLLK +  P +  ++A A+        
Sbjct: 631 EDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRW 690

Query: 871 DAGEMVRSFV---GGLELIVNLLKSDNKEVLASVCAAITNIAKDQENLAVITDHGVVPLL 927
             G  +RS +     L  I +LL ++++ V+ +   A+ N+A D  N  +I  H +  L+
Sbjct: 691 TYGRYIRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLV 750

Query: 928 SKLANTNNN 936
             L     N
Sbjct: 751 KNLPGGQQN 759



 Score = 35.8 bits (81), Expect = 0.22
 Identities = 35/170 (20%), Positives = 77/170 (45%), Gaps = 28/170 (16%)

Query: 524 NPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVA--KFKRARRVVRQHGGITKL 581
           N +++ ++  L G+P++V +LD P K +   A   + N++  + +  +  ++   G+  L
Sbjct: 397 NDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPAL 456

Query: 582 VALLDCAHDSTKPAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLL 641
           V L              L +ARD+++       LW+ S   + K        + ++   L
Sbjct: 457 VRL--------------LRKARDMDLTEVITGTLWNLSSHDSIK--------MEIVDHAL 494

Query: 642 KTSHENMLIPVVGTLQECASEENYRAAIKAERIIEN---LVKNLNSENEQ 688
               + ++IP  G  +E  +E+     I+ E ++ N    ++N++SE  +
Sbjct: 495 HALTDEVIIPHSGWERE-PNEDCKPRHIEWESVLTNTAGCLRNVSSERSE 543



 Score = 32.0 bits (71), Expect = 3.1
 Identities = 33/130 (25%), Positives = 55/130 (42%), Gaps = 16/130 (12%)

Query: 625 KEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECASEENYRAAIKAERIIENLVKNL-- 682
           + A+R+   +  +A LL   HE ++    G L+  A +   +  I  +  I NLVKNL  
Sbjct: 697 RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELI-GKHAIPNLVKNLPG 755

Query: 683 --NSENEQLQEHCAMAIYQ-----CAEDKETRDLVRLHGGLKPLASLLNNTDNKER---- 731
              + +    E   ++I        AE+ E    +R   G++ L  L+N + N+      
Sbjct: 756 GQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLV-LINKSGNRSEKEVR 814

Query: 732 -LAAVTGAIW 740
             A V   IW
Sbjct: 815 AAALVLQTIW 824



 Score = 30.8 bits (68), Expect = 7.0
 Identities = 31/128 (24%), Positives = 53/128 (41%), Gaps = 6/128 (4%)

Query: 721 SLLNNTDNKERLAAVTGAIWKCSISKENVTKF-----REYKAIETLVGLLTDQPEEVLVN 775
           SLL  +     L A  GAI      +    ++     R+ KA+  +  LLT++ E V+  
Sbjct: 664 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKA 723

Query: 776 VVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAVEPESMMIID 835
             GAL     +  N+ ++ K   I  LV  L G  Q    N ++      +   + +I +
Sbjct: 724 ASGALRNLAVDARNKELIGK-HAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 782

Query: 836 RLDGVRLL 843
            L+  + L
Sbjct: 783 NLEAAKKL 790


>gi|146231938 catenin, delta 1 isoform 1A [Homo sapiens]
          Length = 933

 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 100/429 (23%), Positives = 174/429 (40%), Gaps = 66/429 (15%)

Query: 537 LPIMVNILDSPHKSLKCLAAETIANVA-KFKRARRVVRQHGGITKLVALLDCAHDSTKPA 595
           LP ++ +L     ++K  AA  + ++  +  + +  VR+  GI  LV LLD         
Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLD--------- 418

Query: 596 QSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVV-G 654
               +  ++V +  CGAL   S  +   NK AI+   G+P L RLL+ + +  L  V+ G
Sbjct: 419 ----HPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITG 474

Query: 655 TLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKETRD------ 708
           TL   +S +    +IK E I+++ +  L   +E +  H      +  ED + R       
Sbjct: 475 TLWNLSSHD----SIKME-IVDHALHALT--DEVIIPHSGWE-REPNEDCKPRHIEWESV 526

Query: 709 LVRLHGGLKPLASLLNNTDNKERLAAVTGAIWKC--SISKENVTKFREYKAIETLVGLLT 766
           L    G L+ ++S    ++ + +L    G +      +  E   K  + K +E  V LL 
Sbjct: 527 LTNTAGCLRNVSS--ERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLR 584

Query: 767 DQPEEVLVNVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAV 826
           +   +V   +  A  E  QE              P V    G + A      K  G   +
Sbjct: 585 NLSYQVHREIPQA--ERYQE------------AAPNVANNTGPHAASCFGAKKGKGKKPI 630

Query: 827 EPESMMIID---------------RLDGVRLLWSLLK-NPHPDVKASAAWALCPCIKNAK 870
           E  +   +D               + + VR+  SLLK +  P +  ++A A+        
Sbjct: 631 EDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRW 690

Query: 871 DAGEMVRSFV---GGLELIVNLLKSDNKEVLASVCAAITNIAKDQENLAVITDHGVVPLL 927
             G  +RS +     L  I +LL ++++ V+ +   A+ N+A D  N  +I  H +  L+
Sbjct: 691 TYGRYIRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLV 750

Query: 928 SKLANTNNN 936
             L     N
Sbjct: 751 KNLPGGQQN 759



 Score = 35.8 bits (81), Expect = 0.22
 Identities = 35/170 (20%), Positives = 77/170 (45%), Gaps = 28/170 (16%)

Query: 524 NPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVA--KFKRARRVVRQHGGITKL 581
           N +++ ++  L G+P++V +LD P K +   A   + N++  + +  +  ++   G+  L
Sbjct: 397 NDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPAL 456

Query: 582 VALLDCAHDSTKPAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLL 641
           V L              L +ARD+++       LW+ S   + K        + ++   L
Sbjct: 457 VRL--------------LRKARDMDLTEVITGTLWNLSSHDSIK--------MEIVDHAL 494

Query: 642 KTSHENMLIPVVGTLQECASEENYRAAIKAERIIEN---LVKNLNSENEQ 688
               + ++IP  G  +E  +E+     I+ E ++ N    ++N++SE  +
Sbjct: 495 HALTDEVIIPHSGWERE-PNEDCKPRHIEWESVLTNTAGCLRNVSSERSE 543



 Score = 32.0 bits (71), Expect = 3.1
 Identities = 33/130 (25%), Positives = 55/130 (42%), Gaps = 16/130 (12%)

Query: 625 KEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECASEENYRAAIKAERIIENLVKNL-- 682
           + A+R+   +  +A LL   HE ++    G L+  A +   +  I  +  I NLVKNL  
Sbjct: 697 RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELI-GKHAIPNLVKNLPG 755

Query: 683 --NSENEQLQEHCAMAIYQ-----CAEDKETRDLVRLHGGLKPLASLLNNTDNKER---- 731
              + +    E   ++I        AE+ E    +R   G++ L  L+N + N+      
Sbjct: 756 GQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLV-LINKSGNRSEKEVR 814

Query: 732 -LAAVTGAIW 740
             A V   IW
Sbjct: 815 AAALVLQTIW 824



 Score = 30.8 bits (68), Expect = 7.0
 Identities = 31/128 (24%), Positives = 53/128 (41%), Gaps = 6/128 (4%)

Query: 721 SLLNNTDNKERLAAVTGAIWKCSISKENVTKF-----REYKAIETLVGLLTDQPEEVLVN 775
           SLL  +     L A  GAI      +    ++     R+ KA+  +  LLT++ E V+  
Sbjct: 664 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKA 723

Query: 776 VVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAVEPESMMIID 835
             GAL     +  N+ ++ K   I  LV  L G  Q    N ++      +   + +I +
Sbjct: 724 ASGALRNLAVDARNKELIGK-HAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 782

Query: 836 RLDGVRLL 843
            L+  + L
Sbjct: 783 NLEAAKKL 790


>gi|10835010 catenin, delta 1 isoform 1B [Homo sapiens]
          Length = 941

 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 100/429 (23%), Positives = 174/429 (40%), Gaps = 66/429 (15%)

Query: 537 LPIMVNILDSPHKSLKCLAAETIANVA-KFKRARRVVRQHGGITKLVALLDCAHDSTKPA 595
           LP ++ +L     ++K  AA  + ++  +  + +  VR+  GI  LV LLD         
Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLD--------- 418

Query: 596 QSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVV-G 654
               +  ++V +  CGAL   S  +   NK AI+   G+P L RLL+ + +  L  V+ G
Sbjct: 419 ----HPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITG 474

Query: 655 TLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKETRD------ 708
           TL   +S +    +IK E I+++ +  L   +E +  H      +  ED + R       
Sbjct: 475 TLWNLSSHD----SIKME-IVDHALHALT--DEVIIPHSGWE-REPNEDCKPRHIEWESV 526

Query: 709 LVRLHGGLKPLASLLNNTDNKERLAAVTGAIWKC--SISKENVTKFREYKAIETLVGLLT 766
           L    G L+ ++S    ++ + +L    G +      +  E   K  + K +E  V LL 
Sbjct: 527 LTNTAGCLRNVSS--ERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLR 584

Query: 767 DQPEEVLVNVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAV 826
           +   +V   +  A  E  QE              P V    G + A      K  G   +
Sbjct: 585 NLSYQVHREIPQA--ERYQE------------AAPNVANNTGPHAASCFGAKKGKGKKPI 630

Query: 827 EPESMMIID---------------RLDGVRLLWSLLK-NPHPDVKASAAWALCPCIKNAK 870
           E  +   +D               + + VR+  SLLK +  P +  ++A A+        
Sbjct: 631 EDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRW 690

Query: 871 DAGEMVRSFV---GGLELIVNLLKSDNKEVLASVCAAITNIAKDQENLAVITDHGVVPLL 927
             G  +RS +     L  I +LL ++++ V+ +   A+ N+A D  N  +I  H +  L+
Sbjct: 691 TYGRYIRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLV 750

Query: 928 SKLANTNNN 936
             L     N
Sbjct: 751 KNLPGGQQN 759



 Score = 35.8 bits (81), Expect = 0.22
 Identities = 35/170 (20%), Positives = 77/170 (45%), Gaps = 28/170 (16%)

Query: 524 NPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVA--KFKRARRVVRQHGGITKL 581
           N +++ ++  L G+P++V +LD P K +   A   + N++  + +  +  ++   G+  L
Sbjct: 397 NDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPAL 456

Query: 582 VALLDCAHDSTKPAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLL 641
           V L              L +ARD+++       LW+ S   + K        + ++   L
Sbjct: 457 VRL--------------LRKARDMDLTEVITGTLWNLSSHDSIK--------MEIVDHAL 494

Query: 642 KTSHENMLIPVVGTLQECASEENYRAAIKAERIIEN---LVKNLNSENEQ 688
               + ++IP  G  +E  +E+     I+ E ++ N    ++N++SE  +
Sbjct: 495 HALTDEVIIPHSGWERE-PNEDCKPRHIEWESVLTNTAGCLRNVSSERSE 543



 Score = 32.0 bits (71), Expect = 3.1
 Identities = 33/130 (25%), Positives = 55/130 (42%), Gaps = 16/130 (12%)

Query: 625 KEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECASEENYRAAIKAERIIENLVKNL-- 682
           + A+R+   +  +A LL   HE ++    G L+  A +   +  I  +  I NLVKNL  
Sbjct: 697 RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELI-GKHAIPNLVKNLPG 755

Query: 683 --NSENEQLQEHCAMAIYQ-----CAEDKETRDLVRLHGGLKPLASLLNNTDNKER---- 731
              + +    E   ++I        AE+ E    +R   G++ L  L+N + N+      
Sbjct: 756 GQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLV-LINKSGNRSEKEVR 814

Query: 732 -LAAVTGAIW 740
             A V   IW
Sbjct: 815 AAALVLQTIW 824



 Score = 30.8 bits (68), Expect = 7.0
 Identities = 31/128 (24%), Positives = 53/128 (41%), Gaps = 6/128 (4%)

Query: 721 SLLNNTDNKERLAAVTGAIWKCSISKENVTKF-----REYKAIETLVGLLTDQPEEVLVN 775
           SLL  +     L A  GAI      +    ++     R+ KA+  +  LLT++ E V+  
Sbjct: 664 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKA 723

Query: 776 VVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAVEPESMMIID 835
             GAL     +  N+ ++ K   I  LV  L G  Q    N ++      +   + +I +
Sbjct: 724 ASGALRNLAVDARNKELIGK-HAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 782

Query: 836 RLDGVRLL 843
            L+  + L
Sbjct: 783 NLEAAKKL 790


>gi|146231962 catenin, delta 1 isoform 1AB [Homo sapiens]
          Length = 962

 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 100/429 (23%), Positives = 174/429 (40%), Gaps = 66/429 (15%)

Query: 537 LPIMVNILDSPHKSLKCLAAETIANVA-KFKRARRVVRQHGGITKLVALLDCAHDSTKPA 595
           LP ++ +L     ++K  AA  + ++  +  + +  VR+  GI  LV LLD         
Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLD--------- 418

Query: 596 QSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVV-G 654
               +  ++V +  CGAL   S  +   NK AI+   G+P L RLL+ + +  L  V+ G
Sbjct: 419 ----HPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITG 474

Query: 655 TLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKETRD------ 708
           TL   +S +    +IK E I+++ +  L   +E +  H      +  ED + R       
Sbjct: 475 TLWNLSSHD----SIKME-IVDHALHALT--DEVIIPHSGWE-REPNEDCKPRHIEWESV 526

Query: 709 LVRLHGGLKPLASLLNNTDNKERLAAVTGAIWKC--SISKENVTKFREYKAIETLVGLLT 766
           L    G L+ ++S    ++ + +L    G +      +  E   K  + K +E  V LL 
Sbjct: 527 LTNTAGCLRNVSS--ERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLR 584

Query: 767 DQPEEVLVNVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAV 826
           +   +V   +  A  E  QE              P V    G + A      K  G   +
Sbjct: 585 NLSYQVHREIPQA--ERYQE------------AAPNVANNTGPHAASCFGAKKGKGKKPI 630

Query: 827 EPESMMIID---------------RLDGVRLLWSLLK-NPHPDVKASAAWALCPCIKNAK 870
           E  +   +D               + + VR+  SLLK +  P +  ++A A+        
Sbjct: 631 EDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRW 690

Query: 871 DAGEMVRSFV---GGLELIVNLLKSDNKEVLASVCAAITNIAKDQENLAVITDHGVVPLL 927
             G  +RS +     L  I +LL ++++ V+ +   A+ N+A D  N  +I  H +  L+
Sbjct: 691 TYGRYIRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLV 750

Query: 928 SKLANTNNN 936
             L     N
Sbjct: 751 KNLPGGQQN 759



 Score = 35.8 bits (81), Expect = 0.22
 Identities = 35/170 (20%), Positives = 77/170 (45%), Gaps = 28/170 (16%)

Query: 524 NPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVA--KFKRARRVVRQHGGITKL 581
           N +++ ++  L G+P++V +LD P K +   A   + N++  + +  +  ++   G+  L
Sbjct: 397 NDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPAL 456

Query: 582 VALLDCAHDSTKPAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLL 641
           V L              L +ARD+++       LW+ S   + K        + ++   L
Sbjct: 457 VRL--------------LRKARDMDLTEVITGTLWNLSSHDSIK--------MEIVDHAL 494

Query: 642 KTSHENMLIPVVGTLQECASEENYRAAIKAERIIEN---LVKNLNSENEQ 688
               + ++IP  G  +E  +E+     I+ E ++ N    ++N++SE  +
Sbjct: 495 HALTDEVIIPHSGWERE-PNEDCKPRHIEWESVLTNTAGCLRNVSSERSE 543



 Score = 32.0 bits (71), Expect = 3.1
 Identities = 33/130 (25%), Positives = 55/130 (42%), Gaps = 16/130 (12%)

Query: 625 KEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECASEENYRAAIKAERIIENLVKNL-- 682
           + A+R+   +  +A LL   HE ++    G L+  A +   +  I  +  I NLVKNL  
Sbjct: 697 RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELI-GKHAIPNLVKNLPG 755

Query: 683 --NSENEQLQEHCAMAIYQ-----CAEDKETRDLVRLHGGLKPLASLLNNTDNKER---- 731
              + +    E   ++I        AE+ E    +R   G++ L  L+N + N+      
Sbjct: 756 GQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLV-LINKSGNRSEKEVR 814

Query: 732 -LAAVTGAIW 740
             A V   IW
Sbjct: 815 AAALVLQTIW 824



 Score = 30.8 bits (68), Expect = 7.0
 Identities = 31/128 (24%), Positives = 53/128 (41%), Gaps = 6/128 (4%)

Query: 721 SLLNNTDNKERLAAVTGAIWKCSISKENVTKF-----REYKAIETLVGLLTDQPEEVLVN 775
           SLL  +     L A  GAI      +    ++     R+ KA+  +  LLT++ E V+  
Sbjct: 664 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKA 723

Query: 776 VVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAVEPESMMIID 835
             GAL     +  N+ ++ K   I  LV  L G  Q    N ++      +   + +I +
Sbjct: 724 ASGALRNLAVDARNKELIGK-HAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 782

Query: 836 RLDGVRLL 843
            L+  + L
Sbjct: 783 NLEAAKKL 790


>gi|53829376 plakophilin 4 isoform b [Homo sapiens]
          Length = 1149

 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 119/508 (23%), Positives = 188/508 (37%), Gaps = 90/508 (17%)

Query: 537 LPIMVNILDSPHKSLKCLAAETIANVA-KFKRARRVVRQHGGITKLVALLDCAHDSTKPA 595
           LP ++++L     S++  AA  + ++     + +  V + GGI  LV LLD         
Sbjct: 530 LPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRLGGIKHLVDLLD--------- 580

Query: 596 QSSLYEARDVEVARCGALALWSCSKS-HTNKEAIRKAGGIPLLARLLKTSHENMLIPVV- 653
               +   +V+   CGAL      KS   NK A++  GGIP L RLL+ S +  +  +V 
Sbjct: 581 ----HRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVT 636

Query: 654 GTLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKETRDLVRLH 713
           G L   +S +    A+K   II + +  L   N  +  H         +D + +    L 
Sbjct: 637 GVLWNLSSCD----AVKMT-IIRDALSTLT--NTVIVPHSGWNNSSFDDDHKIKFQTSL- 688

Query: 714 GGLKPLASLLNNTDNKERLAAVTGAIWKCSISKENVTKFREYKAIETLVGLL-------- 765
                   +L NT         TG +   S + E   K  + ++ E LV  L        
Sbjct: 689 --------VLRNT---------TGCLRNLSSAGEEARK--QMRSCEGLVDSLLYVIHTCV 729

Query: 766 --TDQPEEVLVNVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGA 823
             +D   + + N V  L       E  V   +  G+  L +LL G       +     G 
Sbjct: 730 NTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLNELDDLL-GKESPSKDSEPSCWGK 788

Query: 824 CAVEPESMMIIDRLDGVRLLWSLLKNP-------HPDVKASAAWALCPCIKNAK---DAG 873
              + +     D+ DGV  +  L K+P       HP V       L      A     AG
Sbjct: 789 KKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAG 848

Query: 874 EMVRSFVG----------------GLELIVNLLKSDNKEVLASVCAAITNIAKDQENLAV 917
            +     G                GL ++V LL+ DN  V++SV  A+ N+A D  N  +
Sbjct: 849 SLQNLSAGNWKFAAYIRAAVRKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKEL 908

Query: 918 ITDHGVVPLLSKLANTNNNKLRHHLAEAISRCCMWG------RNRVAFGEHKAVAPLVRY 971
           I  + +  L+++L   N   +      A   C +         N  A  +   +  LV  
Sbjct: 909 IGKYAMRDLVNRLPGGNGPSVLSDETMAAICCALHEVTSKNMENAKALADSGGIEKLVNI 968

Query: 972 LKS----NDTNVHRATAQALYQLSEDAD 995
            K     +   V +A AQ L  L +  D
Sbjct: 969 TKGRGDRSSLKVVKAAAQVLNTLWQYRD 996


>gi|53829374 plakophilin 4 isoform a [Homo sapiens]
          Length = 1192

 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 119/508 (23%), Positives = 188/508 (37%), Gaps = 90/508 (17%)

Query: 537 LPIMVNILDSPHKSLKCLAAETIANVA-KFKRARRVVRQHGGITKLVALLDCAHDSTKPA 595
           LP ++++L     S++  AA  + ++     + +  V + GGI  LV LLD         
Sbjct: 530 LPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRLGGIKHLVDLLD--------- 580

Query: 596 QSSLYEARDVEVARCGALALWSCSKS-HTNKEAIRKAGGIPLLARLLKTSHENMLIPVV- 653
               +   +V+   CGAL      KS   NK A++  GGIP L RLL+ S +  +  +V 
Sbjct: 581 ----HRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVT 636

Query: 654 GTLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKETRDLVRLH 713
           G L   +S +    A+K   II + +  L   N  +  H         +D + +    L 
Sbjct: 637 GVLWNLSSCD----AVKMT-IIRDALSTLT--NTVIVPHSGWNNSSFDDDHKIKFQTSL- 688

Query: 714 GGLKPLASLLNNTDNKERLAAVTGAIWKCSISKENVTKFREYKAIETLVGLL-------- 765
                   +L NT         TG +   S + E   K  + ++ E LV  L        
Sbjct: 689 --------VLRNT---------TGCLRNLSSAGEEARK--QMRSCEGLVDSLLYVIHTCV 729

Query: 766 --TDQPEEVLVNVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGA 823
             +D   + + N V  L       E  V   +  G+  L +LL G       +     G 
Sbjct: 730 NTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLNELDDLL-GKESPSKDSEPSCWGK 788

Query: 824 CAVEPESMMIIDRLDGVRLLWSLLKNP-------HPDVKASAAWALCPCIKNAK---DAG 873
              + +     D+ DGV  +  L K+P       HP V       L      A     AG
Sbjct: 789 KKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAG 848

Query: 874 EMVRSFVG----------------GLELIVNLLKSDNKEVLASVCAAITNIAKDQENLAV 917
            +     G                GL ++V LL+ DN  V++SV  A+ N+A D  N  +
Sbjct: 849 SLQNLSAGNWKFAAYIRAAVRKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKEL 908

Query: 918 ITDHGVVPLLSKLANTNNNKLRHHLAEAISRCCMWG------RNRVAFGEHKAVAPLVRY 971
           I  + +  L+++L   N   +      A   C +         N  A  +   +  LV  
Sbjct: 909 IGKYAMRDLVNRLPGGNGPSVLSDETMAAICCALHEVTSKNMENAKALADSGGIEKLVNI 968

Query: 972 LKS----NDTNVHRATAQALYQLSEDAD 995
            K     +   V +A AQ L  L +  D
Sbjct: 969 TKGRGDRSSLKVVKAAAQVLNTLWQYRD 996


>gi|6912678 sperm associated antigen 6 isoform 1 [Homo sapiens]
          Length = 509

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 74/329 (22%), Positives = 131/329 (39%), Gaps = 53/329 (16%)

Query: 489 AIRDVGGLEVLINLLETDEVKCKIGSLKILKEIS-HNPQIRQNIVDLGGLPIMVNILDSP 547
           AI D G L+ L+  LE  +   K  +   L+ I+ HN ++ Q +VD G +P++V  +  P
Sbjct: 120 AIVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEP 179

Query: 548 HKSLKCLAAETIANVAKFK-RARRVVRQHGGITKLVALL--------------------- 585
             +LK +AA  ++++AK      + V   G +  L  ++                     
Sbjct: 180 EIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKH 239

Query: 586 --DCAHDSTK----PAQSSLYEARDVEVARCGALALWSCSKSHTNK--EAIRKAGGIPLL 637
             D A    +    P   +  + +D  V +  +  +   +K HT +  + +  AGG+  +
Sbjct: 240 SVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAK-HTPELSQLVVNAGGVAAV 298

Query: 638 ARLLKTSHENMLIPVVGTL-QECASEENYRAAIKAERIIENLVKNLNSENE-QLQEHCAM 695
              + +   N  +P +  L    A  EN   A+   + +  L   L+ E E  ++   A 
Sbjct: 299 IDCIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAW 358

Query: 696 AIYQCA-EDKETRDLVRLHGGLKPLASLLNNTDNKERL-----AAVTGAIWKCSISKENV 749
           A+ Q      E    V +   L  L SL  +T++ E L      A+   + KC+      
Sbjct: 359 ALGQIGRHTPEHARAVAVTNTLPVLLSLYMSTESSEDLQVKSKKAIKNILQKCTY----- 413

Query: 750 TKFREYKAIETLVGLLTDQPEEVLVNVVG 778
                   +  L   L D P  +L +VVG
Sbjct: 414 --------LPALEPFLYDAPPNILKHVVG 434



 Score = 38.9 bits (89), Expect = 0.026
 Identities = 56/291 (19%), Positives = 117/291 (40%), Gaps = 20/291 (6%)

Query: 497 EVLINLLETDEVKCKIGSLKILKEISHNPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAA 556
           +++ +L E +    K  +  +     H+PQ+ Q IVD G L  +V  L+     +K  AA
Sbjct: 87  QLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLEDFDPGVKEAAA 146

Query: 557 ETIANVAKFK-RARRVVRQHGGITKLVALLDCAHDSTKPAQSSLYEARDVEVARCGALAL 615
             +  +A+      + V   G +  LV  +               +  ++ + R  A AL
Sbjct: 147 WALRYIARHNAELSQAVVDAGAVPLLVLCI---------------QEPEIALKRIAASAL 191

Query: 616 WSCSK-SHTNKEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECASEENYRAAIKAE-R 673
              +K S    + +  AG +  LA+++      +   ++  L + +      A +  E  
Sbjct: 192 SDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHSVDLAEMVVEAE 251

Query: 674 IIENLVKNLNSENEQLQEHCAMAIYQCAE-DKETRDLVRLHGGLKPLASLLNNTDNKERL 732
           I   ++  L  ++E ++++ +  I + A+   E   LV   GG+  +   + +     RL
Sbjct: 252 IFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVIDCIGSCKGNTRL 311

Query: 733 AAVTGAIWKCSISKENVTKFREYKAIETLVGLLTDQPEE-VLVNVVGALGE 782
             +    +  + S+         K +  L   L+++PE+ +      ALG+
Sbjct: 312 PGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWALGQ 362



 Score = 31.2 bits (69), Expect = 5.3
 Identities = 47/216 (21%), Positives = 84/216 (38%), Gaps = 4/216 (1%)

Query: 821  VGACAVEPESMMIIDRLDGVRLLWSLLKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFV 880
            V   A  P+++  +     + LL +LL +  P ++ +AA AL        D  E V    
Sbjct: 24   VAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQTAALALGRLANYNDDLAEAVVK-C 82

Query: 881  GGLELIVNLLKSDNKEVLASVCAAITNIAKDQENLA-VITDHGVVPLLSKLANTNNNKLR 939
              L  +V  L   N+    +    +  + K    LA  I D G +  L       +  ++
Sbjct: 83   DILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLEDFDPGVK 142

Query: 940  HHLAEAISRCCMWGRN-RVAFGEHKAVAPLVRYLKSNDTNVHRATAQALYQLSEDADNCI 998
               A A+            A  +  AV  LV  ++  +  + R  A AL  +++ +    
Sbjct: 143  EAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPEIALKRIAASALSDIAKHSPELA 202

Query: 999  -TMHENGAVKLLLDMVGSPDQDLQEAAAGCISNIRR 1033
             T+ + GAV  L  M+ +PD  L+      +S + +
Sbjct: 203  QTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSK 238


>gi|27262641 sperm associated antigen 6 isoform 2 [Homo sapiens]
          Length = 458

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 74/329 (22%), Positives = 131/329 (39%), Gaps = 53/329 (16%)

Query: 489 AIRDVGGLEVLINLLETDEVKCKIGSLKILKEIS-HNPQIRQNIVDLGGLPIMVNILDSP 547
           AI D G L+ L+  LE  +   K  +   L+ I+ HN ++ Q +VD G +P++V  +  P
Sbjct: 120 AIVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEP 179

Query: 548 HKSLKCLAAETIANVAKFK-RARRVVRQHGGITKLVALL--------------------- 585
             +LK +AA  ++++AK      + V   G +  L  ++                     
Sbjct: 180 EIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKH 239

Query: 586 --DCAHDSTK----PAQSSLYEARDVEVARCGALALWSCSKSHTNK--EAIRKAGGIPLL 637
             D A    +    P   +  + +D  V +  +  +   +K HT +  + +  AGG+  +
Sbjct: 240 SVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAK-HTPELSQLVVNAGGVAAV 298

Query: 638 ARLLKTSHENMLIPVVGTL-QECASEENYRAAIKAERIIENLVKNLNSENE-QLQEHCAM 695
              + +   N  +P +  L    A  EN   A+   + +  L   L+ E E  ++   A 
Sbjct: 299 IDCIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAW 358

Query: 696 AIYQCA-EDKETRDLVRLHGGLKPLASLLNNTDNKERL-----AAVTGAIWKCSISKENV 749
           A+ Q      E    V +   L  L SL  +T++ E L      A+   + KC+      
Sbjct: 359 ALGQIGRHTPEHARAVAVTNTLPVLLSLYMSTESSEDLQVKSKKAIKNILQKCTY----- 413

Query: 750 TKFREYKAIETLVGLLTDQPEEVLVNVVG 778
                   +  L   L D P  +L +VVG
Sbjct: 414 --------LPALEPFLYDAPPNILKHVVG 434



 Score = 38.9 bits (89), Expect = 0.026
 Identities = 56/291 (19%), Positives = 117/291 (40%), Gaps = 20/291 (6%)

Query: 497 EVLINLLETDEVKCKIGSLKILKEISHNPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAA 556
           +++ +L E +    K  +  +     H+PQ+ Q IVD G L  +V  L+     +K  AA
Sbjct: 87  QLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLEDFDPGVKEAAA 146

Query: 557 ETIANVAKFK-RARRVVRQHGGITKLVALLDCAHDSTKPAQSSLYEARDVEVARCGALAL 615
             +  +A+      + V   G +  LV  +               +  ++ + R  A AL
Sbjct: 147 WALRYIARHNAELSQAVVDAGAVPLLVLCI---------------QEPEIALKRIAASAL 191

Query: 616 WSCSK-SHTNKEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECASEENYRAAIKAE-R 673
              +K S    + +  AG +  LA+++      +   ++  L + +      A +  E  
Sbjct: 192 SDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHSVDLAEMVVEAE 251

Query: 674 IIENLVKNLNSENEQLQEHCAMAIYQCAE-DKETRDLVRLHGGLKPLASLLNNTDNKERL 732
           I   ++  L  ++E ++++ +  I + A+   E   LV   GG+  +   + +     RL
Sbjct: 252 IFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVIDCIGSCKGNTRL 311

Query: 733 AAVTGAIWKCSISKENVTKFREYKAIETLVGLLTDQPEE-VLVNVVGALGE 782
             +    +  + S+         K +  L   L+++PE+ +      ALG+
Sbjct: 312 PGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWALGQ 362



 Score = 31.2 bits (69), Expect = 5.3
 Identities = 47/216 (21%), Positives = 84/216 (38%), Gaps = 4/216 (1%)

Query: 821  VGACAVEPESMMIIDRLDGVRLLWSLLKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFV 880
            V   A  P+++  +     + LL +LL +  P ++ +AA AL        D  E V    
Sbjct: 24   VAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQTAALALGRLANYNDDLAEAVVK-C 82

Query: 881  GGLELIVNLLKSDNKEVLASVCAAITNIAKDQENLA-VITDHGVVPLLSKLANTNNNKLR 939
              L  +V  L   N+    +    +  + K    LA  I D G +  L       +  ++
Sbjct: 83   DILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLEDFDPGVK 142

Query: 940  HHLAEAISRCCMWGRN-RVAFGEHKAVAPLVRYLKSNDTNVHRATAQALYQLSEDADNCI 998
               A A+            A  +  AV  LV  ++  +  + R  A AL  +++ +    
Sbjct: 143  EAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPEIALKRIAASALSDIAKHSPELA 202

Query: 999  -TMHENGAVKLLLDMVGSPDQDLQEAAAGCISNIRR 1033
             T+ + GAV  L  M+ +PD  L+      +S + +
Sbjct: 203  QTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSK 238


>gi|39812229 karyopherin alpha 5 [Homo sapiens]
          Length = 539

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 52/191 (27%), Positives = 79/191 (41%), Gaps = 10/191 (5%)

Query: 679 VKNLNSENEQLQEHCAMAIYQCAEDK-ETRDLVRLHGGLKPLASLLNNTDNKERLAAVTG 737
           +K LNSE+E +QE    A+   A D  E RD V     L PL  LL N++   RL     
Sbjct: 176 IKLLNSEHEDVQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELLTNSN---RLTTTRN 232

Query: 738 AIWKCS---ISKENVTKFREYK-AIETLVGLLTDQPEEVLVNVVGALGECCQERENRV-I 792
           A+W  S     K     F +    +  L  LL     +VL +V  AL        +++  
Sbjct: 233 AVWALSNLCRGKNPPPNFSKVSPCLNVLSRLLFSSDPDVLADVCWALSYLSDGPNDKIQA 292

Query: 793 VRKCGGIQPLVNLLVGINQALLVNVTKAVGACAVEPE-SMMIIDRLDGVRLLWSLLKNPH 851
           V   G  + LV LL+  +  ++    +AVG      +    +I     +  L  LL +P 
Sbjct: 293 VIDSGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPK 352

Query: 852 PDVKASAAWAL 862
             ++  A W +
Sbjct: 353 ESIRKEACWTV 363



 Score = 35.4 bits (80), Expect = 0.28
 Identities = 23/82 (28%), Positives = 44/82 (53%), Gaps = 1/82 (1%)

Query: 489 AIRDVGGLEVLINLLETDEVKCKIGSLKILKEISHNPQIR-QNIVDLGGLPIMVNILDSP 547
           A+ D G    L+ LL  ++ K    +L+ +  I     I+ Q I++   LP ++++L SP
Sbjct: 292 AVIDSGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSP 351

Query: 548 HKSLKCLAAETIANVAKFKRAR 569
            +S++  A  T++N+    RA+
Sbjct: 352 KESIRKEACWTVSNITAGNRAQ 373



 Score = 32.7 bits (73), Expect = 1.8
 Identities = 44/209 (21%), Positives = 90/209 (43%), Gaps = 17/209 (8%)

Query: 833  IIDRLDGVRLLWSLLKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFVGGLELIVNLLK- 891
            ++     V +   LL + H DV+  A WAL     N        R FV   E++  LL+ 
Sbjct: 165  VVIETGAVPIFIKLLNSEHEDVQEQAVWAL----GNIAGDNAECRDFVLNCEILPPLLEL 220

Query: 892  ---SDNKEVLASVCAAITNIAKDQE---NLAVITDHGVVPLLSKLANTNNNKLRHHLAEA 945
               S+      +   A++N+ + +    N + ++    + +LS+L  +++  +   +  A
Sbjct: 221  LTNSNRLTTTRNAVWALSNLCRGKNPPPNFSKVSP--CLNVLSRLLFSSDPDVLADVCWA 278

Query: 946  ISRCCMWGRNRV-AFGEHKAVAPLVRYLKSNDTNVHRATAQALYQL--SEDADNCITMHE 1002
            +S       +++ A  +      LV  L  ND  V     +A+  +   +D    + ++ 
Sbjct: 279  LSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILN- 337

Query: 1003 NGAVKLLLDMVGSPDQDLQEAAAGCISNI 1031
              A+  LL ++ SP + +++ A   +SNI
Sbjct: 338  CSALPCLLHLLSSPKESIRKEACWTVSNI 366


>gi|28875784 armadillo repeat containing 5 isoform b [Homo sapiens]
          Length = 725

 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 65/252 (25%), Positives = 109/252 (43%), Gaps = 21/252 (8%)

Query: 780  LGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVT-KAVGACAVEPESMMIIDRLD 838
            L +CC E   R  VR+ GGI PLV +L  +    + N T +A+G  A+EPES   I    
Sbjct: 136  LADCCTEGACRTEVRRLGGILPLVTILQCMKTDSIQNRTARALGNLAMEPESCGDIHCAG 195

Query: 839  GVRLLWSLLKNPHPDVKASAAWALCPCIKNAKDAGE--MVRSFVGGLELIVNLLKSDNKE 896
             V LL   L        +    ++   ++N  D+ +  +  +  G +  +  LL +    
Sbjct: 196  AVPLLVESLTACQ---DSQCLQSVVRALRNLADSPQHRLALAQQGAVRPLAELLATAPDA 252

Query: 897  VLA-SVCAAITNIAKD-----QENLAVITDHGVVPLLSKLANTNNNKLRHHLAEAISRCC 950
             L  ++  A+  +++       E L++    G+ PL+S LA+     +R      ++  C
Sbjct: 253  ALTLALVRALLELSRGCSRACAEQLSL--GGGLGPLVS-LASHPKRAVREGTILILANLC 309

Query: 951  MWGRNRVAFGEHKAVAPLVRYLKS-NDTNVHRATAQ-----ALYQLSEDADNCITMHENG 1004
              G  R A G    V  LV  L+   D N    T+Q     A+  L  +A N   + + G
Sbjct: 310  AQGLIRPALGNAGGVEVLVDELRQRRDPNGASPTSQQPLVRAVCLLCREAINRARLRDAG 369

Query: 1005 AVKLLLDMVGSP 1016
             + LL+ ++  P
Sbjct: 370  GLDLLMGLLRDP 381



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 68/276 (24%), Positives = 101/276 (36%), Gaps = 51/276 (18%)

Query: 554 LAAETIANVAKFKRARRVVRQHGGITKLVALLDCAH-DSTKPAQSSLYEARDVEVARCGA 612
           LA   +A+       R  VR+ GGI  LV +L C   DS +   +       +E   CG 
Sbjct: 131 LALSILADCCTEGACRTEVRRLGGILPLVTILQCMKTDSIQNRTARALGNLAMEPESCG- 189

Query: 613 LALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENM-LIPVVGTLQECASEENYRAAIKA 671
                          I  AG +PLL   L    ++  L  VV  L+  A    +R A+  
Sbjct: 190 --------------DIHCAGAVPLLVESLTACQDSQCLQSVVRALRNLADSPQHRLALAQ 235

Query: 672 ERIIENLVKNLNSENE------------QLQEHCAMAIYQCAEDKETRDLVRLHGGLKPL 719
           +  +  L + L +  +            +L   C+ A   CAE       + L GGL PL
Sbjct: 236 QGAVRPLAELLATAPDAALTLALVRALLELSRGCSRA---CAEQ------LSLGGGLGPL 286

Query: 720 ASLLNNTDNKERLAAVTGAIWKCSISKENVTKFREYKAIETLVGLLTDQ---------PE 770
            SL ++     R   +      C+              +E LV  L  +          +
Sbjct: 287 VSLASHPKRAVREGTILILANLCAQGLIR-PALGNAGGVEVLVDELRQRRDPNGASPTSQ 345

Query: 771 EVLVNVVGALGECCQERENRVIVRKCGGIQPLVNLL 806
           + LV  V  L   C+E  NR  +R  GG+  L+ LL
Sbjct: 346 QPLVRAVCLL---CREAINRARLRDAGGLDLLMGLL 378



 Score = 38.1 bits (87), Expect = 0.044
 Identities = 29/103 (28%), Positives = 49/103 (47%), Gaps = 7/103 (6%)

Query: 946  ISRCCMWGRNRVAFGEHKAVAPLVRYLKSNDTN-VHRATAQALYQLSEDADNCITMHENG 1004
            ++ CC  G  R        + PLV  L+   T+ +   TA+AL  L+ + ++C  +H  G
Sbjct: 136  LADCCTEGACRTEVRRLGGILPLVTILQCMKTDSIQNRTARALGNLAMEPESCGDIHCAG 195

Query: 1005 AVKLLLD-MVGSPDQDLQEAAAGCISNI-----RRLALATEKA 1041
            AV LL++ +    D    ++    + N+      RLALA + A
Sbjct: 196  AVPLLVESLTACQDSQCLQSVVRALRNLADSPQHRLALAQQGA 238



 Score = 35.8 bits (81), Expect = 0.22
 Identities = 35/157 (22%), Positives = 70/157 (44%), Gaps = 5/157 (3%)

Query: 880  VGGLELIVNLLKSDNKEVLASVCA-AITNIAKDQENLAVITDHGVVPLL-SKLANTNNNK 937
            +GG+  +V +L+    + + +  A A+ N+A + E+   I   G VPLL   L    +++
Sbjct: 152  LGGILPLVTILQCMKTDSIQNRTARALGNLAMEPESCGDIHCAGAVPLLVESLTACQDSQ 211

Query: 938  LRHHLAEAISRCCMWGRNRVAFGEHKAVAPLVRYL-KSNDTNVHRATAQALYQLSEDADN 996
                +  A+       ++R+A  +  AV PL   L  + D  +  A  +AL +LS     
Sbjct: 212  CLQSVVRALRNLADSPQHRLALAQQGAVRPLAELLATAPDAALTLALVRALLELSRGCSR 271

Query: 997  CIT--MHENGAVKLLLDMVGSPDQDLQEAAAGCISNI 1031
                 +   G +  L+ +   P + ++E     ++N+
Sbjct: 272  ACAEQLSLGGGLGPLVSLASHPKRAVREGTILILANL 308



 Score = 30.8 bits (68), Expect = 7.0
 Identities = 44/213 (20%), Positives = 82/213 (38%), Gaps = 17/213 (7%)

Query: 487 QLAIRDVGGLEVLINLLET-DEVKCKIGSLKILKEISH--NPQIRQNIVDLGGLPIMVNI 543
           +LA+   G +  L  LL T  +    +  ++ L E+S   +    + +   GGL  +V++
Sbjct: 230 RLALAQQGAVRPLAELLATAPDAALTLALVRALLELSRGCSRACAEQLSLGGGLGPLVSL 289

Query: 544 LDSPHKSLKCLAAETIANVAKFKRARRVVRQHGGITKLVALLDCAHDSTKPAQSSLYEAR 603
              P ++++      +AN+      R  +   GG+  LV  L    D    + +S     
Sbjct: 290 ASHPKRAVREGTILILANLCAQGLIRPALGNAGGVEVLVDELRQRRDPNGASPTSQQPLV 349

Query: 604 DVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTS-----HENMLIPVVGTLQE 658
                 C         +   N+  +R AGG+ LL  LL+       H  ++  +VG L +
Sbjct: 350 RAVCLLC---------REAINRARLRDAGGLDLLMGLLRDPRASAWHPRIVAALVGFLYD 400

Query: 659 CASEENYRAAIKAERIIENLVKNLNSENEQLQE 691
             +    +A      +   L      E E+ +E
Sbjct: 401 TGALGRLQALGLVPLLAGQLCGEAGEEEEEGRE 433


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.132    0.379 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,782,460
Number of Sequences: 37866
Number of extensions: 1642765
Number of successful extensions: 7320
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 52
Number of HSP's successfully gapped in prelim test: 134
Number of HSP's that attempted gapping in prelim test: 6559
Number of HSP's gapped (non-prelim): 717
length of query: 1044
length of database: 18,247,518
effective HSP length: 112
effective length of query: 932
effective length of database: 14,006,526
effective search space: 13054082232
effective search space used: 13054082232
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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