BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|31657114 armadillo repeat containing 4 [Homo sapiens] (1044 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|31657114 armadillo repeat containing 4 [Homo sapiens] 2065 0.0 gi|239744025 PREDICTED: hypothetical protein XP_002343006 [Homo ... 303 4e-82 gi|239749766 PREDICTED: similar to armadillo repeat containing 4... 300 6e-81 gi|239755234 PREDICTED: similar to armadillo repeat containing 4... 299 1e-80 gi|189409124 armadillo repeat containing 3 [Homo sapiens] 88 5e-17 gi|91206450 ankyrin and armadillo repeat containing [Homo sapiens] 86 1e-16 gi|4504811 junction plakoglobin [Homo sapiens] 77 1e-13 gi|12056468 junction plakoglobin [Homo sapiens] 77 1e-13 gi|148227672 catenin (cadherin-associated protein), beta 1, 88kD... 72 2e-12 gi|148233338 catenin (cadherin-associated protein), beta 1, 88kD... 72 2e-12 gi|4503131 catenin (cadherin-associated protein), beta 1, 88kDa ... 72 2e-12 gi|11034811 catenin (cadherin-associated protein), delta 2 (neur... 58 5e-08 gi|4504897 karyopherin alpha 2 [Homo sapiens] 56 2e-07 gi|4502247 armadillo repeat protein [Homo sapiens] 54 1e-06 gi|146231975 catenin, delta 1 isoform 3A [Homo sapiens] 52 3e-06 gi|146231948 catenin, delta 1 isoform 3A [Homo sapiens] 52 3e-06 gi|146231994 catenin, delta 1 isoform 3A [Homo sapiens] 52 3e-06 gi|146231946 catenin, delta 1 isoform 3B [Homo sapiens] 52 3e-06 gi|146231991 catenin, delta 1 isoform 3AB [Homo sapiens] 52 3e-06 gi|146231942 catenin, delta 1 isoform 1A [Homo sapiens] 52 3e-06 gi|146231968 catenin, delta 1 isoform 1A [Homo sapiens] 52 3e-06 gi|146231938 catenin, delta 1 isoform 1A [Homo sapiens] 52 3e-06 gi|10835010 catenin, delta 1 isoform 1B [Homo sapiens] 52 3e-06 gi|146231962 catenin, delta 1 isoform 1AB [Homo sapiens] 52 3e-06 gi|53829376 plakophilin 4 isoform b [Homo sapiens] 50 1e-05 gi|53829374 plakophilin 4 isoform a [Homo sapiens] 50 1e-05 gi|6912678 sperm associated antigen 6 isoform 1 [Homo sapiens] 49 2e-05 gi|27262641 sperm associated antigen 6 isoform 2 [Homo sapiens] 49 2e-05 gi|39812229 karyopherin alpha 5 [Homo sapiens] 49 2e-05 gi|28875784 armadillo repeat containing 5 isoform b [Homo sapiens] 48 6e-05 >gi|31657114 armadillo repeat containing 4 [Homo sapiens] Length = 1044 Score = 2065 bits (5349), Expect = 0.0 Identities = 1044/1044 (100%), Positives = 1044/1044 (100%) Query: 1 MGVALRKLTQWTAAGHGTGILEITPLNEAILKEIIVFVESFIYKHPQEAKFVFVEPLEWN 60 MGVALRKLTQWTAAGHGTGILEITPLNEAILKEIIVFVESFIYKHPQEAKFVFVEPLEWN Sbjct: 1 MGVALRKLTQWTAAGHGTGILEITPLNEAILKEIIVFVESFIYKHPQEAKFVFVEPLEWN 60 Query: 61 TSLAPSAFESGYVVSETTVKSEEVDKNGQPLLFLSVPQIKIRSFGQLSRLLLIAKTGKLK 120 TSLAPSAFESGYVVSETTVKSEEVDKNGQPLLFLSVPQIKIRSFGQLSRLLLIAKTGKLK Sbjct: 61 TSLAPSAFESGYVVSETTVKSEEVDKNGQPLLFLSVPQIKIRSFGQLSRLLLIAKTGKLK 120 Query: 121 EAQACVEANRDPIVKILGSDYNTMKENSIALNILGKITRDDDPESEIKMKIAMLLKQLDL 180 EAQACVEANRDPIVKILGSDYNTMKENSIALNILGKITRDDDPESEIKMKIAMLLKQLDL Sbjct: 121 EAQACVEANRDPIVKILGSDYNTMKENSIALNILGKITRDDDPESEIKMKIAMLLKQLDL 180 Query: 181 HLLNHSLKHISLEISLSPMTVKKDIELLKRFSGKGNQTVLESIEYTSDYEFSNGCRAPPW 240 HLLNHSLKHISLEISLSPMTVKKDIELLKRFSGKGNQTVLESIEYTSDYEFSNGCRAPPW Sbjct: 181 HLLNHSLKHISLEISLSPMTVKKDIELLKRFSGKGNQTVLESIEYTSDYEFSNGCRAPPW 240 Query: 241 RQIRGEICYVLVKPHDGETLCITCSAGGVFLNGGKTDDEGDVNYERKGSIYKNLVTFLRE 300 RQIRGEICYVLVKPHDGETLCITCSAGGVFLNGGKTDDEGDVNYERKGSIYKNLVTFLRE Sbjct: 241 RQIRGEICYVLVKPHDGETLCITCSAGGVFLNGGKTDDEGDVNYERKGSIYKNLVTFLRE 300 Query: 301 KSPKFSENMSKLGISFSEDQQKEKDQLGKAPKKEEAAALRKDISGSDKRSLEKNQINFWR 360 KSPKFSENMSKLGISFSEDQQKEKDQLGKAPKKEEAAALRKDISGSDKRSLEKNQINFWR Sbjct: 301 KSPKFSENMSKLGISFSEDQQKEKDQLGKAPKKEEAAALRKDISGSDKRSLEKNQINFWR 360 Query: 361 NQMTKRWEPSLNWKTTVNYKGKGSAKEIQEDKHTGKLEKPRPSVSHGRAQLLRKSAEKIE 420 NQMTKRWEPSLNWKTTVNYKGKGSAKEIQEDKHTGKLEKPRPSVSHGRAQLLRKSAEKIE Sbjct: 361 NQMTKRWEPSLNWKTTVNYKGKGSAKEIQEDKHTGKLEKPRPSVSHGRAQLLRKSAEKIE 420 Query: 421 ETVSDSSSESEEDEEPPDHRQEASADLPSEYWQIQKLVKYLKGGNQTATVIALCSMRDFS 480 ETVSDSSSESEEDEEPPDHRQEASADLPSEYWQIQKLVKYLKGGNQTATVIALCSMRDFS Sbjct: 421 ETVSDSSSESEEDEEPPDHRQEASADLPSEYWQIQKLVKYLKGGNQTATVIALCSMRDFS 480 Query: 481 LAQETCQLAIRDVGGLEVLINLLETDEVKCKIGSLKILKEISHNPQIRQNIVDLGGLPIM 540 LAQETCQLAIRDVGGLEVLINLLETDEVKCKIGSLKILKEISHNPQIRQNIVDLGGLPIM Sbjct: 481 LAQETCQLAIRDVGGLEVLINLLETDEVKCKIGSLKILKEISHNPQIRQNIVDLGGLPIM 540 Query: 541 VNILDSPHKSLKCLAAETIANVAKFKRARRVVRQHGGITKLVALLDCAHDSTKPAQSSLY 600 VNILDSPHKSLKCLAAETIANVAKFKRARRVVRQHGGITKLVALLDCAHDSTKPAQSSLY Sbjct: 541 VNILDSPHKSLKCLAAETIANVAKFKRARRVVRQHGGITKLVALLDCAHDSTKPAQSSLY 600 Query: 601 EARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECA 660 EARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECA Sbjct: 601 EARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECA 660 Query: 661 SEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKETRDLVRLHGGLKPLA 720 SEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKETRDLVRLHGGLKPLA Sbjct: 661 SEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKETRDLVRLHGGLKPLA 720 Query: 721 SLLNNTDNKERLAAVTGAIWKCSISKENVTKFREYKAIETLVGLLTDQPEEVLVNVVGAL 780 SLLNNTDNKERLAAVTGAIWKCSISKENVTKFREYKAIETLVGLLTDQPEEVLVNVVGAL Sbjct: 721 SLLNNTDNKERLAAVTGAIWKCSISKENVTKFREYKAIETLVGLLTDQPEEVLVNVVGAL 780 Query: 781 GECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAVEPESMMIIDRLDGV 840 GECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAVEPESMMIIDRLDGV Sbjct: 781 GECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAVEPESMMIIDRLDGV 840 Query: 841 RLLWSLLKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFVGGLELIVNLLKSDNKEVLAS 900 RLLWSLLKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFVGGLELIVNLLKSDNKEVLAS Sbjct: 841 RLLWSLLKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFVGGLELIVNLLKSDNKEVLAS 900 Query: 901 VCAAITNIAKDQENLAVITDHGVVPLLSKLANTNNNKLRHHLAEAISRCCMWGRNRVAFG 960 VCAAITNIAKDQENLAVITDHGVVPLLSKLANTNNNKLRHHLAEAISRCCMWGRNRVAFG Sbjct: 901 VCAAITNIAKDQENLAVITDHGVVPLLSKLANTNNNKLRHHLAEAISRCCMWGRNRVAFG 960 Query: 961 EHKAVAPLVRYLKSNDTNVHRATAQALYQLSEDADNCITMHENGAVKLLLDMVGSPDQDL 1020 EHKAVAPLVRYLKSNDTNVHRATAQALYQLSEDADNCITMHENGAVKLLLDMVGSPDQDL Sbjct: 961 EHKAVAPLVRYLKSNDTNVHRATAQALYQLSEDADNCITMHENGAVKLLLDMVGSPDQDL 1020 Query: 1021 QEAAAGCISNIRRLALATEKARYT 1044 QEAAAGCISNIRRLALATEKARYT Sbjct: 1021 QEAAAGCISNIRRLALATEKARYT 1044 >gi|239744025 PREDICTED: hypothetical protein XP_002343006 [Homo sapiens] Length = 265 Score = 303 bits (777), Expect = 4e-82 Identities = 153/171 (89%), Positives = 158/171 (92%), Gaps = 3/171 (1%) Query: 312 LGISFSEDQQKEKDQLGKAPKKEEAAALRKDISGSDKRSLEKNQINFWRNQMTKRWEPSL 371 +GISF+EDQQKEKDQLGKAPKKE+AAAL KDISGS KRSLEKNQINFWRNQMTKRWEPSL Sbjct: 35 IGISFNEDQQKEKDQLGKAPKKEKAAALHKDISGSGKRSLEKNQINFWRNQMTKRWEPSL 94 Query: 372 NWKTTVNYKGKGSAKEIQEDKHTGKLEKPRPSVSHGRAQLLRKSAEKIEETVSDSSSESE 431 NWKTTVNYKGKGSAKEIQEDKHTGKLEKPRPSVSHGRAQLLRKSAEKIEETVSDSSSESE Sbjct: 95 NWKTTVNYKGKGSAKEIQEDKHTGKLEKPRPSVSHGRAQLLRKSAEKIEETVSDSSSESE 154 Query: 432 EDEEPPDHRQEASADLPSEYWQIQKLVKYLKGGNQTATVIALCSMRDFSLA 482 EDEEPPDHRQEASADLPSEYWQIQKLVKYLK Q+ I C +DF LA Sbjct: 155 EDEEPPDHRQEASADLPSEYWQIQKLVKYLKIREQS---IFSCPSKDFMLA 202 Score = 70.9 bits (172), Expect = 6e-12 Identities = 34/35 (97%), Positives = 34/35 (97%) Query: 1 MGVALRKLTQWTAAGHGTGILEITPLNEAILKEII 35 MGVALRKLTQWTAAGHGTGILEITPLNE ILKEII Sbjct: 1 MGVALRKLTQWTAAGHGTGILEITPLNEVILKEII 35 >gi|239749766 PREDICTED: similar to armadillo repeat containing 4 [Homo sapiens] Length = 367 Score = 300 bits (767), Expect = 6e-81 Identities = 147/151 (97%), Positives = 149/151 (98%) Query: 312 LGISFSEDQQKEKDQLGKAPKKEEAAALRKDISGSDKRSLEKNQINFWRNQMTKRWEPSL 371 +GISF+EDQQKEKDQLGKAPKKEEAAAL KDISGS KRSLEKNQINFWRNQMTKRWEPSL Sbjct: 35 IGISFNEDQQKEKDQLGKAPKKEEAAALHKDISGSGKRSLEKNQINFWRNQMTKRWEPSL 94 Query: 372 NWKTTVNYKGKGSAKEIQEDKHTGKLEKPRPSVSHGRAQLLRKSAEKIEETVSDSSSESE 431 NWKTTVNYKGKGSAKEIQEDKHTGKLEKPRPSVSHGRAQLLRKSAEKIEETVSDSSSESE Sbjct: 95 NWKTTVNYKGKGSAKEIQEDKHTGKLEKPRPSVSHGRAQLLRKSAEKIEETVSDSSSESE 154 Query: 432 EDEEPPDHRQEASADLPSEYWQIQKLVKYLK 462 EDEEPPDHRQEASADLPSEYWQIQKLVKYLK Sbjct: 155 EDEEPPDHRQEASADLPSEYWQIQKLVKYLK 185 Score = 70.9 bits (172), Expect = 6e-12 Identities = 34/35 (97%), Positives = 34/35 (97%) Query: 1 MGVALRKLTQWTAAGHGTGILEITPLNEAILKEII 35 MGVALRKLTQWTAAGHGTGILEITPLNE ILKEII Sbjct: 1 MGVALRKLTQWTAAGHGTGILEITPLNEVILKEII 35 >gi|239755234 PREDICTED: similar to armadillo repeat containing 4 [Homo sapiens] Length = 362 Score = 299 bits (765), Expect = 1e-80 Identities = 147/150 (98%), Positives = 148/150 (98%) Query: 313 GISFSEDQQKEKDQLGKAPKKEEAAALRKDISGSDKRSLEKNQINFWRNQMTKRWEPSLN 372 GISF+EDQQKEKDQLGKAPKKEEAAAL KDISGS KRSLEKNQINFWRNQMTKRWEPSLN Sbjct: 31 GISFNEDQQKEKDQLGKAPKKEEAAALHKDISGSGKRSLEKNQINFWRNQMTKRWEPSLN 90 Query: 373 WKTTVNYKGKGSAKEIQEDKHTGKLEKPRPSVSHGRAQLLRKSAEKIEETVSDSSSESEE 432 WKTTVNYKGKGSAKEIQEDKHTGKLEKPRPSVSHGRAQLLRKSAEKIEETVSDSSSESEE Sbjct: 91 WKTTVNYKGKGSAKEIQEDKHTGKLEKPRPSVSHGRAQLLRKSAEKIEETVSDSSSESEE 150 Query: 433 DEEPPDHRQEASADLPSEYWQIQKLVKYLK 462 DEEPPDHRQEASADLPSEYWQIQKLVKYLK Sbjct: 151 DEEPPDHRQEASADLPSEYWQIQKLVKYLK 180 >gi|189409124 armadillo repeat containing 3 [Homo sapiens] Length = 872 Score = 87.8 bits (216), Expect = 5e-17 Identities = 97/506 (19%), Positives = 205/506 (40%), Gaps = 19/506 (3%) Query: 528 RQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVAKFKRARRVVRQHGGITKLVALLDC 587 + +++LG + + +L K ++ A +A ++++R+ + ++A Sbjct: 60 KTTLLELGAVEPLTKLLTHEDKIVRRNATMIFGILASNNDVKKLLRELDVMNSVIA---- 115 Query: 588 AHDSTKPAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHEN 647 L +V + +L L + S +T+K I + GG+ L RLL + + Sbjct: 116 ----------QLAPEEEVVIHEFASLCLANMSAEYTSKVQIFEHGGLEPLIRLLSSPDPD 165 Query: 648 MLIPVVGTLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKETR 707 + + + + RA ++ I ++ L SE +Q + A DKE+R Sbjct: 166 VKKNSMECIYNLVQDFQCRAKLQELNAIPPILDLLKSEYPVIQLLALKTLGVIANDKESR 225 Query: 708 DLVRLHGGLKPLASLLNNTDNKERLAAVTGAIWKCSISKENVTKFREYKAIETLVGLLTD 767 ++R + GL L +L + + I C + + + ++ ++ L+ + Sbjct: 226 TMLRDNQGLDHLIKILETKELNDLHIEALAVIANCLEDMDTMVQIQQTGGLKKLLSFAEN 285 Query: 768 QP-EEVLVNVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAV 826 ++ N A+ + + ENR + + + LV LL N + ++A+ A Sbjct: 286 STIPDIQKNAAKAITKAAYDPENRKLFHEQEVEKCLVALLGSENDGTKIAASQAISAMCE 345 Query: 827 EPESMMIIDRLDGVRLLWSLLKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFVGGLELI 886 S + G+ L LLK+ + +V+ +AA AL + A + G++ + Sbjct: 346 NSGSKDFFNN-QGIPQLIQLLKSDNEEVREAAALALAN-LTTCNPANANAAAEADGIDPL 403 Query: 887 VNLLKSDNKEVLASVCAAITNIAKDQENLAVITDHGVVPLLSKLANTNNNKLRHHLAEAI 946 +NLL S +A+ +TN+A + I +H ++ + + N ++ A A+ Sbjct: 404 INLLSSKRDGAIANAATVLTNMAMQEPLRLNIQNHDIMHAIISPLRSANTVVQSKAALAV 463 Query: 947 SRCCMWGRNRVAFGEHKAVAPLVRYLKSNDTNVHRATAQALYQLSEDADNCITMHENGAV 1006 + R + PLV L+S + V + + A+ + D + GA+ Sbjct: 464 TATACDVEARTELRNSGGLEPLVELLRSKNDEVRKHASWAVMVCAGDELTANELCRLGAL 523 Query: 1007 KLL--LDMVGSPDQDLQEAAAGCISN 1030 +L +++ G+ EAA + N Sbjct: 524 DILEEVNVSGTRKNKFSEAAYNKLLN 549 Score = 80.1 bits (196), Expect = 1e-14 Identities = 103/445 (23%), Positives = 182/445 (40%), Gaps = 24/445 (5%) Query: 498 VLINLLETDEVKCKIGSLKILKEISHNPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAE 557 V+ L +EV + L +S + I + GGL ++ +L SP +K + E Sbjct: 113 VIAQLAPEEEVVIHEFASLCLANMSAEYTSKVQIFEHGGLEPLIRLLSSPDPDVKKNSME 172 Query: 558 TIANVAKFKRARRVVRQHGGITKLVALLDCAHDSTKPAQSSLYEARDVEVARCGALALWS 617 I N+ + + R +++ I ++ LL +S + + + G +A Sbjct: 173 CIYNLVQDFQCRAKLQELNAIPPILDLL----------KSEYPVIQLLALKTLGVIA--- 219 Query: 618 CSKSHTNKEAIRKAGGIPLLARLLKTSHENML-IPVVGTLQECASEENYRAAIKAERIIE 676 ++ +R G+ L ++L+T N L I + + C + + I+ ++ Sbjct: 220 --NDKESRTMLRDNQGLDHLIKILETKELNDLHIEALAVIANCLEDMDTMVQIQQTGGLK 277 Query: 677 NLVKNL-NSENEQLQEHCAMAIYQCAEDKETRDLVRLHGGLKPLASLLNNTDNKERLAAV 735 L+ NS +Q++ A AI + A D E R L K L +LL + ++ ++AA Sbjct: 278 KLLSFAENSTIPDIQKNAAKAITKAAYDPENRKLFHEQEVEKCLVALLGSENDGTKIAAS 337 Query: 736 TGAIWKCSISKENVTKFREYKAIETLVGLLTDQPEEVLVNVVGALGECCQ-ERENRVIVR 794 C S F + I L+ LL EEV AL N Sbjct: 338 QAISAMCENSGSK--DFFNNQGIPQLIQLLKSDNEEVREAAALALANLTTCNPANANAAA 395 Query: 795 KCGGIQPLVNLLVGINQALLVNVTKAVGACAVEPESMMIIDRLDGVRLLWSLLKNPHPDV 854 + GI PL+NLL + N + A++ + I D + + S L++ + V Sbjct: 396 EADGIDPLINLLSSKRDGAIANAATVLTNMAMQEPLRLNIQNHDIMHAIISPLRSANTVV 455 Query: 855 KASAAWALCPCIKNAKDAGEMVRSFVGGLELIVNLLKSDNKEVLASVCAAITNIAKDQEN 914 ++ AA A+ + + E+ S GGLE +V LL+S N EV A+ A D+ Sbjct: 456 QSKAALAVTATACDVEARTELRNS--GGLEPLVELLRSKNDEVRKHASWAVMVCAGDELT 513 Query: 915 LAVITDHGVVPLLSK--LANTNNNK 937 + G + +L + ++ T NK Sbjct: 514 ANELCRLGALDILEEVNVSGTRKNK 538 Score = 73.9 bits (180), Expect = 7e-13 Identities = 81/318 (25%), Positives = 137/318 (43%), Gaps = 30/318 (9%) Query: 454 IQKLVKYLKGGNQTATVIALCSMRDFSLAQETCQLAIRDVGGLEVLINLLETDEVK-CKI 512 I ++ LK ++AL ++ + +E+ + +RD GL+ LI +LET E+ I Sbjct: 193 IPPILDLLKSEYPVIQLLALKTLGVIANDKES-RTMLRDNQGLDHLIKILETKELNDLHI 251 Query: 513 GSLKILKEISHNPQIRQNIVDLGGLPIMVNILD-SPHKSLKCLAAETIANVAKFKRARRV 571 +L ++ + I GGL +++ + S ++ AA+ I A R++ Sbjct: 252 EALAVIANCLEDMDTMVQIQQTGGLKKLLSFAENSTIPDIQKNAAKAITKAAYDPENRKL 311 Query: 572 VRQHGGITKLVALLDCAHDSTKPAQSS-------------------------LYEARDVE 606 + LVALL +D TK A S L ++ + E Sbjct: 312 FHEQEVEKCLVALLGSENDGTKIAASQAISAMCENSGSKDFFNNQGIPQLIQLLKSDNEE 371 Query: 607 VARCGALALWSCSKSH-TNKEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECASEENY 665 V ALAL + + + N A +A GI L LL + + + L A +E Sbjct: 372 VREAAALALANLTTCNPANANAAAEADGIDPLINLLSSKRDGAIANAATVLTNMAMQEPL 431 Query: 666 RAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKETRDLVRLHGGLKPLASLLNN 725 R I+ I+ ++ L S N +Q A+A+ A D E R +R GGL+PL LL + Sbjct: 432 RLNIQNHDIMHAIISPLRSANTVVQSKAALAVTATACDVEARTELRNSGGLEPLVELLRS 491 Query: 726 TDNKERLAAVTGAIWKCS 743 +++ R A + A+ C+ Sbjct: 492 KNDEVRKHA-SWAVMVCA 508 Score = 70.5 bits (171), Expect = 8e-12 Identities = 80/354 (22%), Positives = 151/354 (42%), Gaps = 46/354 (12%) Query: 722 LLNNTDNKERLAAVTGAIWKCSIS-KENVTKFREYKAIETLVGLLTDQ------------ 768 L+ N+ +E LA AI+K ++ +EN T E A+E L LLT + Sbjct: 32 LMLNSPEEEILAKACEAIYKFALKGEENKTTLLELGAVEPLTKLLTHEDKIVRRNATMIF 91 Query: 769 ----------------------------PEEVLVNVVGA--LGECCQERENRVIVRKCGG 798 EEV+++ + L E ++V + + GG Sbjct: 92 GILASNNDVKKLLRELDVMNSVIAQLAPEEEVVIHEFASLCLANMSAEYTSKVQIFEHGG 151 Query: 799 IQPLVNLLVGINQALLVNVTKAVGACAVEPESMMIIDRLDGVRLLWSLLKNPHPDVKASA 858 ++PL+ LL + + N + + + + + L+ + + LLK+ +P ++ A Sbjct: 152 LEPLIRLLSSPDPDVKKNSMECIYNLVQDFQCRAKLQELNAIPPILDLLKSEYPVIQLLA 211 Query: 859 AWALCPCIKNAKDAGEMVRSFVGGLELIVNLLKSDNKEVLASVCAAITNIAKDQENLAVI 918 L I N K++ M+R G LI L + ++ A I N +D + + I Sbjct: 212 LKTL-GVIANDKESRTMLRDNQGLDHLIKILETKELNDLHIEALAVIANCLEDMDTMVQI 270 Query: 919 TD-HGVVPLLSKLANTNNNKLRHHLAEAISRCCMWGRNRVAFGEHKAVAPLVRYLKSNDT 977 G+ LLS N+ ++ + A+AI++ NR F E + LV L S + Sbjct: 271 QQTGGLKKLLSFAENSTIPDIQKNAAKAITKAAYDPENRKLFHEQEVEKCLVALLGSEND 330 Query: 978 NVHRATAQALYQLSEDADNCITMHENGAVKLLLDMVGSPDQDLQEAAAGCISNI 1031 A +QA+ + E++ + N + L+ ++ S +++++EAAA ++N+ Sbjct: 331 GTKIAASQAISAMCENSGS-KDFFNNQGIPQLIQLLKSDNEEVREAAALALANL 383 Score = 65.1 bits (157), Expect = 3e-10 Identities = 60/279 (21%), Positives = 122/279 (43%), Gaps = 4/279 (1%) Query: 754 EYKAIETLVGLLTDQPEEVLVNVVGALGE-CCQERENRVIVRKCGGIQPLVNLLVGINQA 812 E K T+V +L EE+L A+ + + EN+ + + G ++PL LL ++ Sbjct: 23 ESKKAATVVLMLNSPEEEILAKACEAIYKFALKGEENKTTLLELGAVEPLTKLLTHEDKI 82 Query: 813 LLVNVTKAVGACAVEPESMMIIDRLDGVRLLWSLLKNPHPDVKASAAWALCPCIKNAKDA 872 + N T G A + ++ LD + + + L P +V +LC +A+ Sbjct: 83 VRRNATMIFGILASNNDVKKLLRELDVMNSVIAQLA-PEEEVVIHEFASLCLANMSAEYT 141 Query: 873 GEMVRSFVGGLELIVNLLKSDNKEVLASVCAAITNIAKDQENLAVITDHGVVPLLSKLAN 932 ++ GGLE ++ LL S + +V + I N+ +D + A + + +P + L Sbjct: 142 SKVQIFEHGGLEPLIRLLSSPDPDVKKNSMECIYNLVQDFQCRAKLQELNAIPPILDLLK 201 Query: 933 TNNNKLRHHLAEAISRCCMWGRNRVAFGEHKAVAPLVRYLKSNDTN-VHRATAQALYQLS 991 + ++ + + +R +++ + L++ L++ + N +H + Sbjct: 202 SEYPVIQLLALKTLGVIANDKESRTMLRDNQGLDHLIKILETKELNDLHIEALAVIANCL 261 Query: 992 EDADNCITMHENGAVKLLLDMV-GSPDQDLQEAAAGCIS 1029 ED D + + + G +K LL S D+Q+ AA I+ Sbjct: 262 EDMDTMVQIQQTGGLKKLLSFAENSTIPDIQKNAAKAIT 300 Score = 48.9 bits (115), Expect = 2e-05 Identities = 34/148 (22%), Positives = 68/148 (45%), Gaps = 2/148 (1%) Query: 886 IVNLLKSDNKEVLASVCAAITNIA-KDQENLAVITDHGVVPLLSKLANTNNNKLRHHLAE 944 +V +L S +E+LA C AI A K +EN + + G V L+KL + +R + Sbjct: 30 VVLMLNSPEEEILAKACEAIYKFALKGEENKTTLLELGAVEPLTKLLTHEDKIVRRNATM 89 Query: 945 AISRCCMWGRNRVAFGEHKAVAPLVRYLK-SNDTNVHRATAQALYQLSEDADNCITMHEN 1003 + E + ++ L + +H + L +S + + + + E+ Sbjct: 90 IFGILASNNDVKKLLRELDVMNSVIAQLAPEEEVVIHEFASLCLANMSAEYTSKVQIFEH 149 Query: 1004 GAVKLLLDMVGSPDQDLQEAAAGCISNI 1031 G ++ L+ ++ SPD D+++ + CI N+ Sbjct: 150 GGLEPLIRLLSSPDPDVKKNSMECIYNL 177 >gi|91206450 ankyrin and armadillo repeat containing [Homo sapiens] Length = 1363 Score = 86.3 bits (212), Expect = 1e-16 Identities = 114/471 (24%), Positives = 207/471 (43%), Gaps = 38/471 (8%) Query: 457 LVKYLKGGNQTATVIALCSMRDFSLAQETCQLAIRDVGGLEVLINLLETDEVKCKIGSLK 516 LV+ L+ + ++A+ S+ LA + I D G + LINLL++ ++K + ++ Sbjct: 634 LVEMLQCESYKRRMMAVMSLEVICLANDQYWRCILDAGTIPALINLLKSSKIKLQCKTVG 693 Query: 517 ILKEISHNPQIRQNIVDLGGLPIMVNIL--DSPHKSLKCLAAETIANVAKFKRARRVVRQ 574 +L IS + +V+ GG+P ++N+L D P +C A + ++A+ + + V+ + Sbjct: 694 LLSNISTHKSAVHALVEAGGIPSLINLLVCDEPEVHSRC--AVILYDIAQCEN-KDVIAK 750 Query: 575 HGGITKLVALLDCAHDSTKPAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGI 634 + GI L+ LL+ ++ V V C + C + N+ A+R+ G+ Sbjct: 751 YNGIPSLINLLNLNIENVL-----------VNVMNCIRVL---CIGNENNQRAVREHKGL 796 Query: 635 PLLARLLKTSHENMLIPVVGTLQECASE-ENYRAAIKAERIIENLVKNLNSENEQLQEHC 693 P L R L + + + + E + + + AI E I LV + +Q Sbjct: 797 PYLIRFLSSDSDVLKAVSSAAIAEVGRDNKEIQDAIAMEGAIPPLVALFKGKQISVQMKG 856 Query: 694 AMAIYQCAEDKETRDLVRLHGGL-KPLASLLN--NTDNKERLAAVTGAIWKCSISKEN-V 749 AMA+ A L L K L LL D KE+ A A+ ++ ++ + Sbjct: 857 AMAVESLASHNALIQKAFLEKSLTKYLLKLLKAFQIDVKEQGAVALWALAGQTLKQQKYM 916 Query: 750 TKFREYKAIETLVGLLTDQPEEVLVNVVGALGECCQERENRVIVRKCGGIQPLVNLL--V 807 + Y I ++ + + + V V AL + + +N++ + GI PLV LL Sbjct: 917 AEQIGYSFIINMLLSPSAKMQYVGGEAVIALSKDSRMHQNQIC--EGNGIAPLVRLLRIS 974 Query: 808 GINQALLVNVTKAVGACAV------EPESMMIIDRLDGVRLLWSLLKN-PHPDVKASAAW 860 I + L++V +AVG+ + P S + + +L LL+N P P++K A+ Sbjct: 975 TIAEGTLLSVIRAVGSICIGVAHTSNPVSQQFVVDENAFPVLIQLLRNHPSPNIKVEVAF 1034 Query: 861 ALCPCIKNAKDAGEMVRSFVGGLEL--IVNLLKSDNKEVLASVCAAITNIA 909 +L CI D + G E ++ LL S K++ A+T A Sbjct: 1035 SLA-CIVLGNDVLQKDLHENEGFEYADVLYLLHSTEKDICLRAGYALTLFA 1084 Score = 48.1 bits (113), Expect = 4e-05 Identities = 34/114 (29%), Positives = 54/114 (47%), Gaps = 2/114 (1%) Query: 881 GGLELIVNLLKSDNKEVLASVCAAITNIAKDQENLAVITDHGVVPLLSKLANTNNNKLRH 940 GG+ ++NLL D EV S CA I EN VI + +P L L N N + Sbjct: 712 GGIPSLINLLVCDEPEV-HSRCAVILYDIAQCENKDVIAKYNGIPSLINLLNLNIENVLV 770 Query: 941 HLAEAISRCCMWG-RNRVAFGEHKAVAPLVRYLKSNDTNVHRATAQALYQLSED 993 ++ I C+ N+ A EHK + L+R+L S+ + ++ A+ ++ D Sbjct: 771 NVMNCIRVLCIGNENNQRAVREHKGLPYLIRFLSSDSDVLKAVSSAAIAEVGRD 824 Score = 45.1 bits (105), Expect = 4e-04 Identities = 72/315 (22%), Positives = 122/315 (38%), Gaps = 19/315 (6%) Query: 717 KPLASLLNNTDNKERLAAVTGAIWKCSISKENVTKFREYKAIETLVGLLTDQPEEVLVNV 776 K L +L K R+ AV C + + + I L+ LL ++ Sbjct: 632 KTLVEMLQCESYKRRMMAVMSLEVICLANDQYWRCILDAGTIPALINLLKSSKIKLQCKT 691 Query: 777 VGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAV------EPES 830 VG L + + + GGI L+NLLV + + CAV + E+ Sbjct: 692 VGLLSNISTHKSAVHALVEAGGIPSLINLLV-------CDEPEVHSRCAVILYDIAQCEN 744 Query: 831 MMIIDRLDGVRLLWSLLKNPHPDVKASAAWAL-CPCIKNAKDAGEMVRSFVGGLELIVNL 889 +I + +G+ L +LL +V + + CI N + VR G L ++ Sbjct: 745 KDVIAKYNGIPSLINLLNLNIENVLVNVMNCIRVLCIGNENNQ-RAVREHKG-LPYLIRF 802 Query: 890 LKSDNKEVLASVCAAITNIAKDQENLA-VITDHGVVPLLSKLANTNNNKLRHHLAEAISR 948 L SD+ + A AAI + +D + + I G +P L L ++ A A+ Sbjct: 803 LSSDSDVLKAVSSAAIAEVGRDNKEIQDAIAMEGAIPPLVALFKGKQISVQMKGAMAVES 862 Query: 949 CCMWGR-NRVAFGEHKAVAPLVRYLKSNDTNVHRATAQALYQLS-EDADNCITMHENGAV 1006 + AF E L++ LK+ +V A AL+ L+ + M E Sbjct: 863 LASHNALIQKAFLEKSLTKYLLKLLKAFQIDVKEQGAVALWALAGQTLKQQKYMAEQIGY 922 Query: 1007 KLLLDMVGSPDQDLQ 1021 +++M+ SP +Q Sbjct: 923 SFIINMLLSPSAKMQ 937 Score = 32.0 bits (71), Expect = 3.1 Identities = 29/157 (18%), Positives = 65/157 (41%), Gaps = 8/157 (5%) Query: 881 GGLELIVNLLKSDNKEVLASVCAAITNIAKDQENLAVITDHGVVPLLSKLANTNNNKLRH 940 G + ++NLLKS ++ ++NI+ + + + + G +P L L + ++ Sbjct: 671 GTIPALINLLKSSKIKLQCKTVGLLSNISTHKSAVHALVEAGGIPSLINLLVCDEPEVHS 730 Query: 941 HLAEA---ISRCCMWGRNRVAFGEHKAVAPLVRYLKSNDTNVHRATAQALYQLS-EDADN 996 A I++C N+ ++ + L+ L N NV + L + +N Sbjct: 731 RCAVILYDIAQC----ENKDVIAKYNGIPSLINLLNLNIENVLVNVMNCIRVLCIGNENN 786 Query: 997 CITMHENGAVKLLLDMVGSPDQDLQEAAAGCISNIRR 1033 + E+ + L+ + S L+ ++ I+ + R Sbjct: 787 QRAVREHKGLPYLIRFLSSDSDVLKAVSSAAIAEVGR 823 >gi|4504811 junction plakoglobin [Homo sapiens] Length = 745 Score = 76.6 bits (187), Expect = 1e-13 Identities = 111/528 (21%), Positives = 208/528 (39%), Gaps = 52/528 (9%) Query: 537 LPIMVNILDSPHKSLKCLAAETIANVAKFKRARRVVRQHGGITKLVALLDCAHDSTKPAQ 596 LP + +L+ + AA + ++K + +RR + G +LVA + +T Sbjct: 144 LPELTKLLNDEDPVVVTKAAMIVNQLSKKEASRRALM---GSPQLVAAVVRTMQNTS--- 197 Query: 597 SSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVVGTL 656 D++ ARC L + S AI K+GGIP L R+L + E++L + TL Sbjct: 198 -------DLDTARCTTSILHNLSHHREGLLAIFKSGGIPALVRMLSSPVESVLFYAITTL 250 Query: 657 QE-CASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCA-EDKETRDLVRLHG 714 +E + A++ ++ +V LN N + + A ++E++ ++ +G Sbjct: 251 HNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAITTDCLQLLAYGNQESKLIILANG 310 Query: 715 GLKPLASLLNNTDNKERLAAVTGAIWKCSISKENVTKFREYKAIETLVGLLTDQPEEVLV 774 G + L ++ N ++ L + + S+ N E ++ L LT ++ Sbjct: 311 GPQALVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPAIVEAGGMQALGKHLTSNSPRLVQ 370 Query: 775 NVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNV-TKAVG-----ACAVEP 828 N + L R + K G++ ++ +LV VNV T A G C Sbjct: 371 NCLWTL------RNLSDVATKQEGLESVLKILVNQLSVDDVNVLTCATGTLSNLTCNNSK 424 Query: 829 ESMMIIDRLDGVRLLWSLLKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFVG---GLEL 885 ++ L+ ++L+ D A + + EM ++ V G+ Sbjct: 425 NKTLVTQNSGVEALIHAILRAGDKDDITEPAVCALRHLTSRHPEAEMAQNSVRLNYGIPA 484 Query: 886 IVNLLKSDNK-EVLASVCAAITNIAKDQENLAVITDHGVVPLLSKLANTNNNKLRHHLA- 943 IV LL N+ ++ + I N+A N A + + V+P L +L + + H+A Sbjct: 485 IVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQLLVKAHQDAQRHVAA 544 Query: 944 ------------EAISRCCMWG--------RNRVAFGEHKAVAPLVRYLKSNDTNVHRAT 983 E I C NR+ + V+ L S+ N+ R Sbjct: 545 GTQQPYTDGVRMEEIVEGCTGALHILARDPMNRMEIFRLNTIPLFVQLLYSSVENIQRVA 604 Query: 984 AQALYQLSEDADNCITMHENGAVKLLLDMVGSPDQDLQEAAAGCISNI 1031 A L +L++D + + GA L++++ S ++ AA + I Sbjct: 605 AGVLCELAQDKEAADAIDAEGASAPLMELLHSRNEGTATYAAAVLFRI 652 Score = 65.5 bits (158), Expect = 3e-10 Identities = 113/507 (22%), Positives = 198/507 (39%), Gaps = 60/507 (11%) Query: 501 NLLETDEVKCKIGSLKILKEISHNPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIA 560 N + D +C + IL +SH+ + I GG+P +V +L SP +S+ A T+ Sbjct: 195 NTSDLDTARC---TTSILHNLSHHREGLLAIFKSGGIPALVRMLSSPVESVLFYAITTLH 251 Query: 561 NVAKFKR-ARRVVRQHGGITKLVALLDCAHDSTKPAQSSLYEARDVEVARCGALALWSCS 619 N+ ++ A+ VR G+ K+V LL + P ++ C L + Sbjct: 252 NLLLYQEGAKMAVRLADGLQKMVPLL----NKNNPKFLAI-------TTDCLQLLAYGNQ 300 Query: 620 KSHTNKEAIRKAGGIPLLARLLKT-SHENMLIPVVGTLQECASEENYRAAIKAERIIENL 678 +S K I GG L ++++ S+E +L L+ + + + AI ++ L Sbjct: 301 ES---KLIILANGGPQALVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPAIVEAGGMQAL 357 Query: 679 VKNLNSENEQLQEHCAMAIYQCAEDKETRDLVRLHGGLKPLASLLNN---TDNKERLAAV 735 K+L S + +L ++C + + D+ GL+ + +L N D+ L Sbjct: 358 GKHLTSNSPRLVQNCLWTL------RNLSDVATKQEGLESVLKILVNQLSVDDVNVLTCA 411 Query: 736 TGAI--WKCSISKENVTKFREYKAIETLVG--LLTDQPEEVLVNVVGALGECCQERENRV 791 TG + C+ SK N T + +E L+ L +++ V AL Sbjct: 412 TGTLSNLTCNNSK-NKTLVTQNSGVEALIHAILRAGDKDDITEPAVCALRHLTSRHPEAE 470 Query: 792 I----VRKCGGIQPLVNLLVGINQALLVNVT-KAVGACAVEPESMMIIDRLDGVRLLWSL 846 + VR GI +V LL NQ LV T + A+ P + + + L L Sbjct: 471 MAQNSVRLNYGIPAIVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQL 530 Query: 847 LKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFVGGLELIVNLLKSDNKEVLASVCAAIT 906 L H D + A AG + + G+ + +E++ A+ Sbjct: 531 LVKAHQDAQRHVA------------AGTQ-QPYTDGVRM---------EEIVEGCTGALH 568 Query: 907 NIAKDQENLAVITDHGVVPLLSKLANTNNNKLRHHLAEAISRCCMWGRNRVAFGEHKAVA 966 +A+D N I +PL +L ++ ++ A + A A A Sbjct: 569 ILARDPMNRMEIFRLNTIPLFVQLLYSSVENIQRVAAGVLCELAQDKEAADAIDAEGASA 628 Query: 967 PLVRYLKSNDTNVHRATAQALYQLSED 993 PL+ L S + A L+++SED Sbjct: 629 PLMELLHSRNEGTATYAAAVLFRISED 655 Score = 57.8 bits (138), Expect = 5e-08 Identities = 95/470 (20%), Positives = 193/470 (41%), Gaps = 52/470 (11%) Query: 454 IQKLVKYLKGGNQTATVIALCSMRDFSLAQETCQLAIRDVGGLEVLINLLETDEVKCKIG 513 I LV+ L ++ A+ ++ + L QE ++A+R GL+ ++ LL + K Sbjct: 228 IPALVRMLSSPVESVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAI 287 Query: 514 SLKILKEISH-NPQIRQNIVDLGGLPIMVNIL-DSPHKSLKCLAAETIANVAKFKRARRV 571 + L+ +++ N + + I+ GG +V I+ + ++ L + + ++ + Sbjct: 288 TTDCLQLLAYGNQESKLIILANGGPQALVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPA 347 Query: 572 VRQHGGITKLVALLDCAHDSTKPAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKA 631 + + GG+ L L +S + Q+ L+ R++ S T +E + Sbjct: 348 IVEAGGMQALGKHL--TSNSPRLVQNCLWTLRNL-------------SDVATKQEGLESV 392 Query: 632 GGIPLLARLLKTSHENMLIPVVGTLQE--CASEENYRAAIKAERIIENLVKNL--NSENE 687 + +L L N+L GTL C + +N + + +E L+ + + + Sbjct: 393 --LKILVNQLSVDDVNVLTCATGTLSNLTCNNSKN-KTLVTQNSGVEALIHAILRAGDKD 449 Query: 688 QLQEHCAMAIYQCA----EDKETRDLVRLHGGLKPLASLLNNTDNKERLAAVTGAIWKCS 743 + E A+ E + ++ VRL+ G+ + LLN + + A G I + Sbjct: 450 DITEPAVCALRHLTSRHPEAEMAQNSVRLNYGIPAIVKLLNQPNQWPLVKATIGLIRNLA 509 Query: 744 ISKENVTKFREYKAIETLVGLLTDQPEEVLVNVVGALGECCQERENRVIVRKCGGIQPLV 803 + N +E I LV LL ++ +V G QP Sbjct: 510 LCPANHAPLQEAAVIPRLVQLLVKAHQDAQRHVA------------------AGTQQPYT 551 Query: 804 NLLVGIN-QALLVNVTKAVGACAVEPESMMIIDRLDGVRLLWSLLKNPHPDVKASAAWAL 862 + G+ + ++ T A+ A +P + M I RL+ + L LL + +++ AA L Sbjct: 552 D---GVRMEEIVEGCTGALHILARDPMNRMEIFRLNTIPLFVQLLYSSVENIQRVAAGVL 608 Query: 863 CPCIKNAKDAGEMVRSFVGGLELIVNLLKSDNKEVLASVCAAITNIAKDQ 912 C ++ K+A + + + G ++ LL S N+ A + I++D+ Sbjct: 609 CELAQD-KEAADAIDA-EGASAPLMELLHSRNEGTATYAAAVLFRISEDK 656 >gi|12056468 junction plakoglobin [Homo sapiens] Length = 745 Score = 76.6 bits (187), Expect = 1e-13 Identities = 111/528 (21%), Positives = 208/528 (39%), Gaps = 52/528 (9%) Query: 537 LPIMVNILDSPHKSLKCLAAETIANVAKFKRARRVVRQHGGITKLVALLDCAHDSTKPAQ 596 LP + +L+ + AA + ++K + +RR + G +LVA + +T Sbjct: 144 LPELTKLLNDEDPVVVTKAAMIVNQLSKKEASRRALM---GSPQLVAAVVRTMQNTS--- 197 Query: 597 SSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVVGTL 656 D++ ARC L + S AI K+GGIP L R+L + E++L + TL Sbjct: 198 -------DLDTARCTTSILHNLSHHREGLLAIFKSGGIPALVRMLSSPVESVLFYAITTL 250 Query: 657 QE-CASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCA-EDKETRDLVRLHG 714 +E + A++ ++ +V LN N + + A ++E++ ++ +G Sbjct: 251 HNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAITTDCLQLLAYGNQESKLIILANG 310 Query: 715 GLKPLASLLNNTDNKERLAAVTGAIWKCSISKENVTKFREYKAIETLVGLLTDQPEEVLV 774 G + L ++ N ++ L + + S+ N E ++ L LT ++ Sbjct: 311 GPQALVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPAIVEAGGMQALGKHLTSNSPRLVQ 370 Query: 775 NVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNV-TKAVG-----ACAVEP 828 N + L R + K G++ ++ +LV VNV T A G C Sbjct: 371 NCLWTL------RNLSDVATKQEGLESVLKILVNQLSVDDVNVLTCATGTLSNLTCNNSK 424 Query: 829 ESMMIIDRLDGVRLLWSLLKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFVG---GLEL 885 ++ L+ ++L+ D A + + EM ++ V G+ Sbjct: 425 NKTLVTQNSGVEALIHAILRAGDKDDITEPAVCALRHLTSRHPEAEMAQNSVRLNYGIPA 484 Query: 886 IVNLLKSDNK-EVLASVCAAITNIAKDQENLAVITDHGVVPLLSKLANTNNNKLRHHLA- 943 IV LL N+ ++ + I N+A N A + + V+P L +L + + H+A Sbjct: 485 IVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQLLVKAHQDAQRHVAA 544 Query: 944 ------------EAISRCCMWG--------RNRVAFGEHKAVAPLVRYLKSNDTNVHRAT 983 E I C NR+ + V+ L S+ N+ R Sbjct: 545 GTQQPYTDGVRMEEIVEGCTGALHILARDPMNRMEIFRLNTIPLFVQLLYSSVENIQRVA 604 Query: 984 AQALYQLSEDADNCITMHENGAVKLLLDMVGSPDQDLQEAAAGCISNI 1031 A L +L++D + + GA L++++ S ++ AA + I Sbjct: 605 AGVLCELAQDKEAADAIDAEGASAPLMELLHSRNEGTATYAAAVLFRI 652 Score = 65.5 bits (158), Expect = 3e-10 Identities = 113/507 (22%), Positives = 198/507 (39%), Gaps = 60/507 (11%) Query: 501 NLLETDEVKCKIGSLKILKEISHNPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIA 560 N + D +C + IL +SH+ + I GG+P +V +L SP +S+ A T+ Sbjct: 195 NTSDLDTARC---TTSILHNLSHHREGLLAIFKSGGIPALVRMLSSPVESVLFYAITTLH 251 Query: 561 NVAKFKR-ARRVVRQHGGITKLVALLDCAHDSTKPAQSSLYEARDVEVARCGALALWSCS 619 N+ ++ A+ VR G+ K+V LL + P ++ C L + Sbjct: 252 NLLLYQEGAKMAVRLADGLQKMVPLL----NKNNPKFLAI-------TTDCLQLLAYGNQ 300 Query: 620 KSHTNKEAIRKAGGIPLLARLLKT-SHENMLIPVVGTLQECASEENYRAAIKAERIIENL 678 +S K I GG L ++++ S+E +L L+ + + + AI ++ L Sbjct: 301 ES---KLIILANGGPQALVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPAIVEAGGMQAL 357 Query: 679 VKNLNSENEQLQEHCAMAIYQCAEDKETRDLVRLHGGLKPLASLLNN---TDNKERLAAV 735 K+L S + +L ++C + + D+ GL+ + +L N D+ L Sbjct: 358 GKHLTSNSPRLVQNCLWTL------RNLSDVATKQEGLESVLKILVNQLSVDDVNVLTCA 411 Query: 736 TGAI--WKCSISKENVTKFREYKAIETLVG--LLTDQPEEVLVNVVGALGECCQERENRV 791 TG + C+ SK N T + +E L+ L +++ V AL Sbjct: 412 TGTLSNLTCNNSK-NKTLVTQNSGVEALIHAILRAGDKDDITEPAVCALRHLTSRHPEAE 470 Query: 792 I----VRKCGGIQPLVNLLVGINQALLVNVT-KAVGACAVEPESMMIIDRLDGVRLLWSL 846 + VR GI +V LL NQ LV T + A+ P + + + L L Sbjct: 471 MAQNSVRLNYGIPAIVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQL 530 Query: 847 LKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFVGGLELIVNLLKSDNKEVLASVCAAIT 906 L H D + A AG + + G+ + +E++ A+ Sbjct: 531 LVKAHQDAQRHVA------------AGTQ-QPYTDGVRM---------EEIVEGCTGALH 568 Query: 907 NIAKDQENLAVITDHGVVPLLSKLANTNNNKLRHHLAEAISRCCMWGRNRVAFGEHKAVA 966 +A+D N I +PL +L ++ ++ A + A A A Sbjct: 569 ILARDPMNRMEIFRLNTIPLFVQLLYSSVENIQRVAAGVLCELAQDKEAADAIDAEGASA 628 Query: 967 PLVRYLKSNDTNVHRATAQALYQLSED 993 PL+ L S + A L+++SED Sbjct: 629 PLMELLHSRNEGTATYAAAVLFRISED 655 Score = 57.8 bits (138), Expect = 5e-08 Identities = 95/470 (20%), Positives = 193/470 (41%), Gaps = 52/470 (11%) Query: 454 IQKLVKYLKGGNQTATVIALCSMRDFSLAQETCQLAIRDVGGLEVLINLLETDEVKCKIG 513 I LV+ L ++ A+ ++ + L QE ++A+R GL+ ++ LL + K Sbjct: 228 IPALVRMLSSPVESVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAI 287 Query: 514 SLKILKEISH-NPQIRQNIVDLGGLPIMVNIL-DSPHKSLKCLAAETIANVAKFKRARRV 571 + L+ +++ N + + I+ GG +V I+ + ++ L + + ++ + Sbjct: 288 TTDCLQLLAYGNQESKLIILANGGPQALVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPA 347 Query: 572 VRQHGGITKLVALLDCAHDSTKPAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKA 631 + + GG+ L L +S + Q+ L+ R++ S T +E + Sbjct: 348 IVEAGGMQALGKHL--TSNSPRLVQNCLWTLRNL-------------SDVATKQEGLESV 392 Query: 632 GGIPLLARLLKTSHENMLIPVVGTLQE--CASEENYRAAIKAERIIENLVKNL--NSENE 687 + +L L N+L GTL C + +N + + +E L+ + + + Sbjct: 393 --LKILVNQLSVDDVNVLTCATGTLSNLTCNNSKN-KTLVTQNSGVEALIHAILRAGDKD 449 Query: 688 QLQEHCAMAIYQCA----EDKETRDLVRLHGGLKPLASLLNNTDNKERLAAVTGAIWKCS 743 + E A+ E + ++ VRL+ G+ + LLN + + A G I + Sbjct: 450 DITEPAVCALRHLTSRHPEAEMAQNSVRLNYGIPAIVKLLNQPNQWPLVKATIGLIRNLA 509 Query: 744 ISKENVTKFREYKAIETLVGLLTDQPEEVLVNVVGALGECCQERENRVIVRKCGGIQPLV 803 + N +E I LV LL ++ +V G QP Sbjct: 510 LCPANHAPLQEAAVIPRLVQLLVKAHQDAQRHVA------------------AGTQQPYT 551 Query: 804 NLLVGIN-QALLVNVTKAVGACAVEPESMMIIDRLDGVRLLWSLLKNPHPDVKASAAWAL 862 + G+ + ++ T A+ A +P + M I RL+ + L LL + +++ AA L Sbjct: 552 D---GVRMEEIVEGCTGALHILARDPMNRMEIFRLNTIPLFVQLLYSSVENIQRVAAGVL 608 Query: 863 CPCIKNAKDAGEMVRSFVGGLELIVNLLKSDNKEVLASVCAAITNIAKDQ 912 C ++ K+A + + + G ++ LL S N+ A + I++D+ Sbjct: 609 CELAQD-KEAADAIDA-EGASAPLMELLHSRNEGTATYAAAVLFRISEDK 656 >gi|148227672 catenin (cadherin-associated protein), beta 1, 88kDa [Homo sapiens] Length = 781 Score = 72.4 bits (176), Expect = 2e-12 Identities = 66/232 (28%), Positives = 104/232 (44%), Gaps = 14/232 (6%) Query: 487 QLAIRDVGGLEVLINLL-----ETDEVKCKIGSLKILKEISHNPQIRQNIVDLG-GLPIM 540 ++ + VGG+E L+ + D + I +L+ L ++ QN V L GLP++ Sbjct: 435 KMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVV 494 Query: 541 VNILDSP-HKSLKCLAAETIANVAKFKRARRVVRQHGGITKLVALLDCAHDSTK------ 593 V +L P H L I N+A +R+ G I +LV LL AH T+ Sbjct: 495 VKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMG 554 Query: 594 -PAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPV 652 Q + R E+ AL ++ N+ IR IPL +LL + EN+ Sbjct: 555 GTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVA 614 Query: 653 VGTLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDK 704 G L E A ++ AI+AE L + L+S NE + + A +++ +EDK Sbjct: 615 AGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSEDK 666 Score = 69.7 bits (169), Expect = 1e-11 Identities = 105/458 (22%), Positives = 193/458 (42%), Gaps = 45/458 (9%) Query: 598 SLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQ 657 ++ DVE ARC A L + S AI K+GGIP L ++L + +++L + TL Sbjct: 201 TMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLH 260 Query: 658 E-CASEENYRAAIKAERIIENLVKNLNSENEQ---LQEHCAMAIYQCAEDKETRDLVRLH 713 +E + A++ ++ +V LN N + + C + ++E++ ++ Sbjct: 261 NLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQIL--AYGNQESKLIILAS 318 Query: 714 GGLKPLASLLNNTDNKERLAAVTGAIWK-CSISKENVTKFREYKAIETLVGLLTDQPEEV 772 GG + L +++ T E+L T + K S+ N E ++ L LTD + + Sbjct: 319 GGPQALVNIM-RTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRL 377 Query: 773 LVNVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVN-VTKAVGACA----VE 827 + N + L R K G++ L+ LV + + +N VT A G + Sbjct: 378 VQNCLWTL------RNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNN 431 Query: 828 PESMMIIDRLDGVRLL--WSLLKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFVG---G 882 ++ M++ ++ G+ L L D+ A AL ++A EM ++ V G Sbjct: 432 YKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEA-EMAQNAVRLHYG 490 Query: 883 LELIVNLLKSDNK-EVLASVCAAITNIAKDQENLAVITDHGVVPLLSKLANTNNNKLRHH 941 L ++V LL + ++ + I N+A N A + + G +P L +L +R H Sbjct: 491 LPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL------VRAH 544 Query: 942 LAEAISRCCMWGRNRVAFGEHKAVAPLVRYLKSNDTNVHRATAQALYQLSEDADNCITMH 1001 + R G + F E + +V AL+ L+ D N I + Sbjct: 545 --QDTQRRTSMGGTQQQFVEGVRMEEIV-----------EGCTGALHILARDVHNRIVIR 591 Query: 1002 ENGAVKLLLDMVGSPDQDLQEAAAGCISNIRRLALATE 1039 + L + ++ SP +++Q AAG + + + A E Sbjct: 592 GLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAE 629 Score = 68.6 bits (166), Expect = 3e-11 Identities = 117/537 (21%), Positives = 208/537 (38%), Gaps = 101/537 (18%) Query: 454 IQKLVKYLKGGNQTATVIALCSMRDFSLAQETCQLAIRDVGGLEVLINLLE-TDEVKCKI 512 I +L K L +Q A + S + + +R + ++ ++ T++V+ Sbjct: 153 IPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETAR 212 Query: 513 GSLKILKEISHNPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVAKFKR-ARRV 571 + L +SH+ + I GG+P +V +L SP S+ A T+ N+ + A+ Sbjct: 213 CTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMA 272 Query: 572 VRQHGGITKLVALLDCAH--------DSTKPAQSSLYEARDVEVARCGALALWSCSKSHT 623 VR GG+ K+VALL+ + D + E++ + +A G AL + +++T Sbjct: 273 VRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYT 332 Query: 624 --------------------NKEAIRKAGGIPLLA--------RLLK------------- 642 NK AI +AGG+ L RL++ Sbjct: 333 YEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAA 392 Query: 643 TSHENMLIPVVGTLQECASEENYRAAIKAERIIENLVKN--------------------- 681 T E M ++GTL + ++ A I+ NL N Sbjct: 393 TKQEGM-EGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTV 451 Query: 682 -LNSENEQLQEHCAMAIYQCA----EDKETRDLVRLHGGLKPLASLLNNTDNKERLAAVT 736 + E + E A+ E + ++ VRLH GL + LL+ + + A Sbjct: 452 LRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATV 511 Query: 737 GAIWKCSISKENVTKFREYKAIETLVGLLTDQPEEVLVNVVGALGECCQERENRVIVRKC 796 G I ++ N RE AI LV LL Q+ + R Sbjct: 512 GLIRNLALCPANHAPLREQGAIPRLVQLLV---------------RAHQDTQRRT---SM 553 Query: 797 GGIQPLVNLLVGIN-QALLVNVTKAVGACAVEPESMMIIDRLDGVRLLWSLLKNPHPDVK 855 GG Q + G+ + ++ T A+ A + + ++I L+ + L LL +P +++ Sbjct: 554 GGTQQ--QFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQ 611 Query: 856 ASAAWALCPCIKNAKDAGEMVRSFVGGLELIVNLLKSDNKEVLASVCAAITNIAKDQ 912 AA LC ++ K+A E + + G + LL S N+ V A + +++D+ Sbjct: 612 RVAAGVLCELAQD-KEAAEAIEA-EGATAPLTELLHSRNEGVATYAAAVLFRMSEDK 666 >gi|148233338 catenin (cadherin-associated protein), beta 1, 88kDa [Homo sapiens] Length = 781 Score = 72.4 bits (176), Expect = 2e-12 Identities = 66/232 (28%), Positives = 104/232 (44%), Gaps = 14/232 (6%) Query: 487 QLAIRDVGGLEVLINLL-----ETDEVKCKIGSLKILKEISHNPQIRQNIVDLG-GLPIM 540 ++ + VGG+E L+ + D + I +L+ L ++ QN V L GLP++ Sbjct: 435 KMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVV 494 Query: 541 VNILDSP-HKSLKCLAAETIANVAKFKRARRVVRQHGGITKLVALLDCAHDSTK------ 593 V +L P H L I N+A +R+ G I +LV LL AH T+ Sbjct: 495 VKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMG 554 Query: 594 -PAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPV 652 Q + R E+ AL ++ N+ IR IPL +LL + EN+ Sbjct: 555 GTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVA 614 Query: 653 VGTLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDK 704 G L E A ++ AI+AE L + L+S NE + + A +++ +EDK Sbjct: 615 AGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSEDK 666 Score = 69.7 bits (169), Expect = 1e-11 Identities = 105/458 (22%), Positives = 193/458 (42%), Gaps = 45/458 (9%) Query: 598 SLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQ 657 ++ DVE ARC A L + S AI K+GGIP L ++L + +++L + TL Sbjct: 201 TMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLH 260 Query: 658 E-CASEENYRAAIKAERIIENLVKNLNSENEQ---LQEHCAMAIYQCAEDKETRDLVRLH 713 +E + A++ ++ +V LN N + + C + ++E++ ++ Sbjct: 261 NLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQIL--AYGNQESKLIILAS 318 Query: 714 GGLKPLASLLNNTDNKERLAAVTGAIWK-CSISKENVTKFREYKAIETLVGLLTDQPEEV 772 GG + L +++ T E+L T + K S+ N E ++ L LTD + + Sbjct: 319 GGPQALVNIM-RTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRL 377 Query: 773 LVNVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVN-VTKAVGACA----VE 827 + N + L R K G++ L+ LV + + +N VT A G + Sbjct: 378 VQNCLWTL------RNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNN 431 Query: 828 PESMMIIDRLDGVRLL--WSLLKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFVG---G 882 ++ M++ ++ G+ L L D+ A AL ++A EM ++ V G Sbjct: 432 YKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEA-EMAQNAVRLHYG 490 Query: 883 LELIVNLLKSDNK-EVLASVCAAITNIAKDQENLAVITDHGVVPLLSKLANTNNNKLRHH 941 L ++V LL + ++ + I N+A N A + + G +P L +L +R H Sbjct: 491 LPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL------VRAH 544 Query: 942 LAEAISRCCMWGRNRVAFGEHKAVAPLVRYLKSNDTNVHRATAQALYQLSEDADNCITMH 1001 + R G + F E + +V AL+ L+ D N I + Sbjct: 545 --QDTQRRTSMGGTQQQFVEGVRMEEIV-----------EGCTGALHILARDVHNRIVIR 591 Query: 1002 ENGAVKLLLDMVGSPDQDLQEAAAGCISNIRRLALATE 1039 + L + ++ SP +++Q AAG + + + A E Sbjct: 592 GLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAE 629 Score = 68.6 bits (166), Expect = 3e-11 Identities = 117/537 (21%), Positives = 208/537 (38%), Gaps = 101/537 (18%) Query: 454 IQKLVKYLKGGNQTATVIALCSMRDFSLAQETCQLAIRDVGGLEVLINLLE-TDEVKCKI 512 I +L K L +Q A + S + + +R + ++ ++ T++V+ Sbjct: 153 IPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETAR 212 Query: 513 GSLKILKEISHNPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVAKFKR-ARRV 571 + L +SH+ + I GG+P +V +L SP S+ A T+ N+ + A+ Sbjct: 213 CTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMA 272 Query: 572 VRQHGGITKLVALLDCAH--------DSTKPAQSSLYEARDVEVARCGALALWSCSKSHT 623 VR GG+ K+VALL+ + D + E++ + +A G AL + +++T Sbjct: 273 VRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYT 332 Query: 624 --------------------NKEAIRKAGGIPLLA--------RLLK------------- 642 NK AI +AGG+ L RL++ Sbjct: 333 YEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAA 392 Query: 643 TSHENMLIPVVGTLQECASEENYRAAIKAERIIENLVKN--------------------- 681 T E M ++GTL + ++ A I+ NL N Sbjct: 393 TKQEGM-EGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTV 451 Query: 682 -LNSENEQLQEHCAMAIYQCA----EDKETRDLVRLHGGLKPLASLLNNTDNKERLAAVT 736 + E + E A+ E + ++ VRLH GL + LL+ + + A Sbjct: 452 LRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATV 511 Query: 737 GAIWKCSISKENVTKFREYKAIETLVGLLTDQPEEVLVNVVGALGECCQERENRVIVRKC 796 G I ++ N RE AI LV LL Q+ + R Sbjct: 512 GLIRNLALCPANHAPLREQGAIPRLVQLLV---------------RAHQDTQRRT---SM 553 Query: 797 GGIQPLVNLLVGIN-QALLVNVTKAVGACAVEPESMMIIDRLDGVRLLWSLLKNPHPDVK 855 GG Q + G+ + ++ T A+ A + + ++I L+ + L LL +P +++ Sbjct: 554 GGTQQ--QFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQ 611 Query: 856 ASAAWALCPCIKNAKDAGEMVRSFVGGLELIVNLLKSDNKEVLASVCAAITNIAKDQ 912 AA LC ++ K+A E + + G + LL S N+ V A + +++D+ Sbjct: 612 RVAAGVLCELAQD-KEAAEAIEA-EGATAPLTELLHSRNEGVATYAAAVLFRMSEDK 666 >gi|4503131 catenin (cadherin-associated protein), beta 1, 88kDa [Homo sapiens] Length = 781 Score = 72.4 bits (176), Expect = 2e-12 Identities = 66/232 (28%), Positives = 104/232 (44%), Gaps = 14/232 (6%) Query: 487 QLAIRDVGGLEVLINLL-----ETDEVKCKIGSLKILKEISHNPQIRQNIVDLG-GLPIM 540 ++ + VGG+E L+ + D + I +L+ L ++ QN V L GLP++ Sbjct: 435 KMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVV 494 Query: 541 VNILDSP-HKSLKCLAAETIANVAKFKRARRVVRQHGGITKLVALLDCAHDSTK------ 593 V +L P H L I N+A +R+ G I +LV LL AH T+ Sbjct: 495 VKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMG 554 Query: 594 -PAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPV 652 Q + R E+ AL ++ N+ IR IPL +LL + EN+ Sbjct: 555 GTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVA 614 Query: 653 VGTLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDK 704 G L E A ++ AI+AE L + L+S NE + + A +++ +EDK Sbjct: 615 AGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSEDK 666 Score = 69.7 bits (169), Expect = 1e-11 Identities = 105/458 (22%), Positives = 193/458 (42%), Gaps = 45/458 (9%) Query: 598 SLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQ 657 ++ DVE ARC A L + S AI K+GGIP L ++L + +++L + TL Sbjct: 201 TMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLH 260 Query: 658 E-CASEENYRAAIKAERIIENLVKNLNSENEQ---LQEHCAMAIYQCAEDKETRDLVRLH 713 +E + A++ ++ +V LN N + + C + ++E++ ++ Sbjct: 261 NLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQIL--AYGNQESKLIILAS 318 Query: 714 GGLKPLASLLNNTDNKERLAAVTGAIWK-CSISKENVTKFREYKAIETLVGLLTDQPEEV 772 GG + L +++ T E+L T + K S+ N E ++ L LTD + + Sbjct: 319 GGPQALVNIM-RTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRL 377 Query: 773 LVNVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVN-VTKAVGACA----VE 827 + N + L R K G++ L+ LV + + +N VT A G + Sbjct: 378 VQNCLWTL------RNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNN 431 Query: 828 PESMMIIDRLDGVRLL--WSLLKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFVG---G 882 ++ M++ ++ G+ L L D+ A AL ++A EM ++ V G Sbjct: 432 YKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEA-EMAQNAVRLHYG 490 Query: 883 LELIVNLLKSDNK-EVLASVCAAITNIAKDQENLAVITDHGVVPLLSKLANTNNNKLRHH 941 L ++V LL + ++ + I N+A N A + + G +P L +L +R H Sbjct: 491 LPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL------VRAH 544 Query: 942 LAEAISRCCMWGRNRVAFGEHKAVAPLVRYLKSNDTNVHRATAQALYQLSEDADNCITMH 1001 + R G + F E + +V AL+ L+ D N I + Sbjct: 545 --QDTQRRTSMGGTQQQFVEGVRMEEIV-----------EGCTGALHILARDVHNRIVIR 591 Query: 1002 ENGAVKLLLDMVGSPDQDLQEAAAGCISNIRRLALATE 1039 + L + ++ SP +++Q AAG + + + A E Sbjct: 592 GLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAE 629 Score = 68.6 bits (166), Expect = 3e-11 Identities = 117/537 (21%), Positives = 208/537 (38%), Gaps = 101/537 (18%) Query: 454 IQKLVKYLKGGNQTATVIALCSMRDFSLAQETCQLAIRDVGGLEVLINLLE-TDEVKCKI 512 I +L K L +Q A + S + + +R + ++ ++ T++V+ Sbjct: 153 IPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETAR 212 Query: 513 GSLKILKEISHNPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVAKFKR-ARRV 571 + L +SH+ + I GG+P +V +L SP S+ A T+ N+ + A+ Sbjct: 213 CTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMA 272 Query: 572 VRQHGGITKLVALLDCAH--------DSTKPAQSSLYEARDVEVARCGALALWSCSKSHT 623 VR GG+ K+VALL+ + D + E++ + +A G AL + +++T Sbjct: 273 VRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYT 332 Query: 624 --------------------NKEAIRKAGGIPLLA--------RLLK------------- 642 NK AI +AGG+ L RL++ Sbjct: 333 YEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAA 392 Query: 643 TSHENMLIPVVGTLQECASEENYRAAIKAERIIENLVKN--------------------- 681 T E M ++GTL + ++ A I+ NL N Sbjct: 393 TKQEGM-EGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTV 451 Query: 682 -LNSENEQLQEHCAMAIYQCA----EDKETRDLVRLHGGLKPLASLLNNTDNKERLAAVT 736 + E + E A+ E + ++ VRLH GL + LL+ + + A Sbjct: 452 LRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATV 511 Query: 737 GAIWKCSISKENVTKFREYKAIETLVGLLTDQPEEVLVNVVGALGECCQERENRVIVRKC 796 G I ++ N RE AI LV LL Q+ + R Sbjct: 512 GLIRNLALCPANHAPLREQGAIPRLVQLLV---------------RAHQDTQRRT---SM 553 Query: 797 GGIQPLVNLLVGIN-QALLVNVTKAVGACAVEPESMMIIDRLDGVRLLWSLLKNPHPDVK 855 GG Q + G+ + ++ T A+ A + + ++I L+ + L LL +P +++ Sbjct: 554 GGTQQ--QFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQ 611 Query: 856 ASAAWALCPCIKNAKDAGEMVRSFVGGLELIVNLLKSDNKEVLASVCAAITNIAKDQ 912 AA LC ++ K+A E + + G + LL S N+ V A + +++D+ Sbjct: 612 RVAAGVLCELAQD-KEAAEAIEA-EGATAPLTELLHSRNEGVATYAAAVLFRMSEDK 666 >gi|11034811 catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) [Homo sapiens] Length = 1225 Score = 57.8 bits (138), Expect = 5e-08 Identities = 97/437 (22%), Positives = 176/437 (40%), Gaps = 78/437 (17%) Query: 537 LPIMVNILDSPHKSLKCLAAETIANVA-KFKRARRVVRQHGGITKLVALLDCAHDSTKPA 595 LP ++ +L S++ AA + ++ + + +R+ GGI LV LLD Sbjct: 552 LPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGIQLLVDLLD--------- 602 Query: 596 QSSLYEARDVEVARCGALALWSCSKSHT-NKEAIRKAGGIPLLARLL-KTSHENMLIPVV 653 + +V + CGAL K++ NK A++ GGIP L RLL KT+ + V Sbjct: 603 ----HRMTEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDLEIRELVT 658 Query: 654 GTLQECASEENYRAAI--KAERIIEN--LVKNLNSENEQLQEHCAMAIYQCAEDKETRDL 709 G L +S + + I A ++ N ++ + EN LQ+ + ++ ++ L Sbjct: 659 GVLWNLSSCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQLHS------SQVL 712 Query: 710 VRLHGGLKPLASLLNNTDNKER---------LAAVTGAIWKCSISKENV----------- 749 G L+ ++S + R L + A+ I + V Sbjct: 713 RNATGCLRNVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCVCILRNLS 772 Query: 750 ------TKFREYKAIETLVGLLTDQPEEVLVNVVGALGECCQERENRVIVRKCGGIQPLV 803 T ++ + L GLL + G G+ ++++++ + G+ PL Sbjct: 773 YRLAAETSQGQHMGTDELDGLLCGEANGKDAESSGCWGKKKKKKKSQ---DQWDGVGPLP 829 Query: 804 NLLVGINQALLVNVTKAVGACAVEPESMMIIDRLDGVRLLWSLLKN-PHPDVKASAAWAL 862 + CA P+ + ++ V+ +LL +PD AA AL Sbjct: 830 D-------------------CAEPPKGIQMLWHPSIVKPYLTLLSECSNPDTLEGAAGAL 870 Query: 863 CPCIKNAKDAGEMVRSFVG---GLELIVNLLKSDNKEVLASVCAAITNIAKDQENLAVIT 919 + +R+ V GL ++V LL+ DN V+ +V A+ N+A D N +I Sbjct: 871 QNLAAGSWKWSVYIRAAVRKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIG 930 Query: 920 DHGVVPLLSKLANTNNN 936 + + L+ +L NN+ Sbjct: 931 KYAMRDLVHRLPGGNNS 947 Score = 38.1 bits (87), Expect = 0.044 Identities = 30/99 (30%), Positives = 51/99 (51%), Gaps = 7/99 (7%) Query: 846 LLKNPHPDVKASAAWALCP-CIKNAKDAGEMVRSFVGGLELIVNLLKSDNKEVLASVCAA 904 +L++ P V+++AA L C + K E+ R GG++L+V+LL EV S C A Sbjct: 558 MLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQ--GGIQLLVDLLDHRMTEVHRSACGA 615 Query: 905 ITNI----AKDQENLAVITDHGVVPLLSKLANTNNNKLR 939 + N+ A D +A+ G+ L+ L T + ++R Sbjct: 616 LRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDLEIR 654 Score = 36.2 bits (82), Expect = 0.17 Identities = 30/108 (27%), Positives = 53/108 (49%), Gaps = 4/108 (3%) Query: 536 GLPIMVNILDSPHKSLKCLAAETIANVAKFKRARRVVRQHGGITKLVALLDCAHDSTKPA 595 GLPI+V +L + + C A + N+A R + ++ ++ + LV L ++S A Sbjct: 893 GLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIGKY-AMRDLVHRLPGGNNSNNTA 951 Query: 596 QSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKT 643 ++ + D A C L +K+ N +A+R AGGI L + K+ Sbjct: 952 SKAMSD--DTVTAVCCTLH-EVITKNMENAKALRDAGGIEKLVGISKS 996 Score = 32.3 bits (72), Expect = 2.4 Identities = 48/187 (25%), Positives = 75/187 (40%), Gaps = 49/187 (26%) Query: 625 KEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECASEENYRAAIKAERIIENLVKNLNS 684 + A+RK G+P+L LL+ ++ ++ V L+ A L+ Sbjct: 885 RAAVRKEKGLPILVELLRIDNDRVVCAVATALRNMA---------------------LDV 923 Query: 685 ENEQLQEHCAMAIYQCAEDKETRDLV-RLHGGLKPLASLLNNTDNKERLAAVTGAIWKCS 743 N++L AM RDLV RL GG + NNT +K A+ C+ Sbjct: 924 RNKELIGKYAM-----------RDLVHRLPGG-----NNSNNTASKAMSDDTVTAVC-CT 966 Query: 744 I------SKENVTKFREYKAIETLVGLLTDQPEEVLVNVVGA----LGECCQERENRVIV 793 + + EN R+ IE LVG+ + ++ VV A L Q R+ R + Sbjct: 967 LHEVITKNMENAKALRDAGGIEKLVGISKSKGDKHSPKVVKAASQVLNSMWQYRDLRSLY 1026 Query: 794 RKCGGIQ 800 +K G Q Sbjct: 1027 KKDGWSQ 1033 >gi|4504897 karyopherin alpha 2 [Homo sapiens] Length = 529 Score = 55.8 bits (133), Expect = 2e-07 Identities = 66/284 (23%), Positives = 113/284 (39%), Gaps = 13/284 (4%) Query: 675 IENLVKNLNSENEQLQEHCAMAIYQCAEDKET-RDLVRLHGGLKPLASLLNNTDNKERLA 733 I + L S + + E A+ A D RDLV +G + PL +LL D Sbjct: 164 IPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAVPDMSSLAC 223 Query: 734 A-VTGAIWKCSISKENVTKFREYKAIE----TLVGLLTDQPEEVLVNVVGALGECCQERE 788 + W S N A+E TLV LL EVL + A+ Sbjct: 224 GYLRNLTWTLSNLCRNKNPAPPIDAVEQILPTLVRLLHHDDPEVLADTCWAISYLTDGPN 283 Query: 789 NRV-IVRKCGGIQPLVNLLVGINQALLVNVTKAVG--ACAVEPESMMIIDRLDGVRLLWS 845 R+ +V K G + LV LL ++ +A+G + ++ ++ID + + S Sbjct: 284 ERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIVTGTDEQTQVVIDA-GALAVFPS 342 Query: 846 LLKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFVGGLELIVNLLKSDNKEVLASVCAAI 905 LL NP +++ A W + +D + V + G + +V++L + + A+ Sbjct: 343 LLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNH-GLVPFLVSVLSKADFKTQKEAVWAV 401 Query: 906 TNIAK--DQENLAVITDHGVVPLLSKLANTNNNKLRHHLAEAIS 947 TN E + + G++ L L + K+ + +AIS Sbjct: 402 TNYTSGGTVEQIVYLVHCGIIEPLMNLLTAKDTKIILVILDAIS 445 Score = 45.8 bits (107), Expect = 2e-04 Identities = 69/305 (22%), Positives = 121/305 (39%), Gaps = 32/305 (10%) Query: 531 IVDLGGLPIMVNILDSPHKSLKCLAAETIANVAKFKRA-RRVVRQHGGITKLVALLDCAH 589 +VD G +P +++L SPH + A + N+A R +V ++G + L+ALL Sbjct: 158 VVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALL---- 213 Query: 590 DSTKPAQSSLYEARDVEVARCGAL--ALWSCSKSHTNK------EAIRKAGGIPLLARLL 641 P SSL CG L W+ S NK +A+ + +P L RLL Sbjct: 214 --AVPDMSSL---------ACGYLRNLTWTLSNLCRNKNPAPPIDAVEQI--LPTLVRLL 260 Query: 642 KTSHENMLIPVVGTLQECASEENYRAAIKAER-IIENLVKNLNSENEQLQEHCAMAI--Y 698 +L + N R + + ++ LVK L + + AI Sbjct: 261 HHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNI 320 Query: 699 QCAEDKETRDLVRLHGGLKPLASLLNNTDNKERLAAVTGAIWKCSISKENVTKFREYKAI 758 D++T+ ++ G L SLL N + A + ++ + + + + Sbjct: 321 VTGTDEQTQVVIDA-GALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLV 379 Query: 759 ETLVGLLTDQPEEVLVNVVGALGECCQ--ERENRVIVRKCGGIQPLVNLLVGINQALLVN 816 LV +L+ + V A+ E V + CG I+PL+NLL + +++ Sbjct: 380 PFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNLLTAKDTKIILV 439 Query: 817 VTKAV 821 + A+ Sbjct: 440 ILDAI 444 Score = 36.6 bits (83), Expect = 0.13 Identities = 44/200 (22%), Positives = 83/200 (41%), Gaps = 19/200 (9%) Query: 845 SLLKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFV---GGLELIVNLLKSDNKEVLASV 901 SLL +PH + A WAL N G + R V G ++ ++ LL + LA Sbjct: 169 SLLASPHAHISEQAVWAL----GNIAGDGSVFRDLVIKYGAVDPLLALLAVPDMSSLA-- 222 Query: 902 CAAITNIAKDQENLA--------VITDHGVVPLLSKLANTNNNKLRHHLAEAISRCCMWG 953 C + N+ NL + ++P L +L + ++ ++ AIS Sbjct: 223 CGYLRNLTWTLSNLCRNKNPAPPIDAVEQILPTLVRLLHHDDPEVLADTCWAISYLTDGP 282 Query: 954 RNRVAFGEHKAVAP-LVRYLKSNDTNVHRATAQALYQLSEDAD-NCITMHENGAVKLLLD 1011 R+ V P LV+ L +++ + +A+ + D + + GA+ + Sbjct: 283 NERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPS 342 Query: 1012 MVGSPDQDLQEAAAGCISNI 1031 ++ +P ++Q+ A +SNI Sbjct: 343 LLTNPKTNIQKEATWTMSNI 362 >gi|4502247 armadillo repeat protein [Homo sapiens] Length = 962 Score = 53.5 bits (127), Expect = 1e-06 Identities = 44/135 (32%), Positives = 66/135 (48%), Gaps = 15/135 (11%) Query: 537 LPIMVNILDSPHKSLKCLAAETIANVA-KFKRARRVVRQHGGITKLVALLDCAHDSTKPA 595 LP ++ +L P +K AA + ++ + + +R VRQ G+ LVALLD Sbjct: 360 LPEVLAMLRHPVDPVKANAAAYLQHLCFENEGVKRRVRQLRGLPLLVALLD--------- 410 Query: 596 QSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVV-G 654 + +V CGAL S + NK AIR GG+P L RLL+ + +N + +V G Sbjct: 411 ----HPRAEVRRRACGALRNLSYGRDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTG 466 Query: 655 TLQECASEENYRAAI 669 TL +S E + I Sbjct: 467 TLWNLSSYEPLKMVI 481 Score = 38.5 bits (88), Expect = 0.033 Identities = 47/183 (25%), Positives = 70/183 (38%), Gaps = 35/183 (19%) Query: 751 KFREYKAIETLVGLLTDQPEEVLVNVVGALGECCQERE--NRVIVRKCGGIQPLVNLLVG 808 + R+ + + LV LL EV GAL R+ N+ +R CGG+ LV LL Sbjct: 395 RVRQLRGLPLLVALLDHPRAEVRRRACGALRNLSYGRDTDNKAAIRDCGGVPALVRLLRA 454 Query: 809 I--NQALLVNVTKAVGACAVEPESMMIIDRLDGVRLL----------WSLLKNPHPDVK- 855 N+ + + EP M+IID G++ L W + P+ D K Sbjct: 455 ARDNEVRELVTGTLWNLSSYEPLKMVIIDH--GLQTLTHEVIVPHSGWE--REPNEDSKP 510 Query: 856 ASAAWA-----LCPCIKNAKDAGE-----------MVRSFVGGLELIVNLLKSDNKEVLA 899 A W C++N G +V + + L+ V +DNK V Sbjct: 511 RDAEWTTVFKNTSGCLRNVSSDGAEARRRLRECEGLVDALLHALQSAVGRKDTDNKSVEN 570 Query: 900 SVC 902 VC Sbjct: 571 CVC 573 Score = 37.4 bits (85), Expect = 0.075 Identities = 20/70 (28%), Positives = 37/70 (52%), Gaps = 2/70 (2%) Query: 524 NPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVAKFKRA--RRVVRQHGGITKL 581 N +++ + L GLP++V +LD P ++ A + N++ + + +R GG+ L Sbjct: 389 NEGVKRRVRQLRGLPLLVALLDHPRAEVRRRACGALRNLSYGRDTDNKAAIRDCGGVPAL 448 Query: 582 VALLDCAHDS 591 V LL A D+ Sbjct: 449 VRLLRAARDN 458 >gi|146231975 catenin, delta 1 isoform 3A [Homo sapiens] Length = 832 Score = 52.0 bits (123), Expect = 3e-06 Identities = 100/429 (23%), Positives = 174/429 (40%), Gaps = 66/429 (15%) Query: 537 LPIMVNILDSPHKSLKCLAAETIANVA-KFKRARRVVRQHGGITKLVALLDCAHDSTKPA 595 LP ++ +L ++K AA + ++ + + + VR+ GI LV LLD Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLD--------- 317 Query: 596 QSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVV-G 654 + ++V + CGAL S + NK AI+ G+P L RLL+ + + L V+ G Sbjct: 318 ----HPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITG 373 Query: 655 TLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKETRD------ 708 TL +S + +IK E I+++ + L +E + H + ED + R Sbjct: 374 TLWNLSSHD----SIKME-IVDHALHALT--DEVIIPHSGWE-REPNEDCKPRHIEWESV 425 Query: 709 LVRLHGGLKPLASLLNNTDNKERLAAVTGAIWKC--SISKENVTKFREYKAIETLVGLLT 766 L G L+ ++S ++ + +L G + + E K + K +E V LL Sbjct: 426 LTNTAGCLRNVSS--ERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLR 483 Query: 767 DQPEEVLVNVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAV 826 + +V + A E QE P V G + A K G + Sbjct: 484 NLSYQVHREIPQA--ERYQE------------AAPNVANNTGPHAASCFGAKKGKGKKPI 529 Query: 827 EPESMMIID---------------RLDGVRLLWSLLK-NPHPDVKASAAWALCPCIKNAK 870 E + +D + + VR+ SLLK + P + ++A A+ Sbjct: 530 EDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRW 589 Query: 871 DAGEMVRSFV---GGLELIVNLLKSDNKEVLASVCAAITNIAKDQENLAVITDHGVVPLL 927 G +RS + L I +LL ++++ V+ + A+ N+A D N +I H + L+ Sbjct: 590 TYGRYIRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLV 649 Query: 928 SKLANTNNN 936 L N Sbjct: 650 KNLPGGQQN 658 Score = 35.8 bits (81), Expect = 0.22 Identities = 35/170 (20%), Positives = 77/170 (45%), Gaps = 28/170 (16%) Query: 524 NPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVA--KFKRARRVVRQHGGITKL 581 N +++ ++ L G+P++V +LD P K + A + N++ + + + ++ G+ L Sbjct: 296 NDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPAL 355 Query: 582 VALLDCAHDSTKPAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLL 641 V L L +ARD+++ LW+ S + K + ++ L Sbjct: 356 VRL--------------LRKARDMDLTEVITGTLWNLSSHDSIK--------MEIVDHAL 393 Query: 642 KTSHENMLIPVVGTLQECASEENYRAAIKAERIIEN---LVKNLNSENEQ 688 + ++IP G +E +E+ I+ E ++ N ++N++SE + Sbjct: 394 HALTDEVIIPHSGWERE-PNEDCKPRHIEWESVLTNTAGCLRNVSSERSE 442 Score = 32.0 bits (71), Expect = 3.1 Identities = 33/130 (25%), Positives = 55/130 (42%), Gaps = 16/130 (12%) Query: 625 KEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECASEENYRAAIKAERIIENLVKNL-- 682 + A+R+ + +A LL HE ++ G L+ A + + I + I NLVKNL Sbjct: 596 RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELI-GKHAIPNLVKNLPG 654 Query: 683 --NSENEQLQEHCAMAIYQ-----CAEDKETRDLVRLHGGLKPLASLLNNTDNKER---- 731 + + E ++I AE+ E +R G++ L L+N + N+ Sbjct: 655 GQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLV-LINKSGNRSEKEVR 713 Query: 732 -LAAVTGAIW 740 A V IW Sbjct: 714 AAALVLQTIW 723 Score = 30.8 bits (68), Expect = 7.0 Identities = 31/128 (24%), Positives = 53/128 (41%), Gaps = 6/128 (4%) Query: 721 SLLNNTDNKERLAAVTGAIWKCSISKENVTKF-----REYKAIETLVGLLTDQPEEVLVN 775 SLL + L A GAI + ++ R+ KA+ + LLT++ E V+ Sbjct: 563 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKA 622 Query: 776 VVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAVEPESMMIID 835 GAL + N+ ++ K I LV L G Q N ++ + + +I + Sbjct: 623 ASGALRNLAVDARNKELIGK-HAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 681 Query: 836 RLDGVRLL 843 L+ + L Sbjct: 682 NLEAAKKL 689 >gi|146231948 catenin, delta 1 isoform 3A [Homo sapiens] Length = 832 Score = 52.0 bits (123), Expect = 3e-06 Identities = 100/429 (23%), Positives = 174/429 (40%), Gaps = 66/429 (15%) Query: 537 LPIMVNILDSPHKSLKCLAAETIANVA-KFKRARRVVRQHGGITKLVALLDCAHDSTKPA 595 LP ++ +L ++K AA + ++ + + + VR+ GI LV LLD Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLD--------- 317 Query: 596 QSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVV-G 654 + ++V + CGAL S + NK AI+ G+P L RLL+ + + L V+ G Sbjct: 318 ----HPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITG 373 Query: 655 TLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKETRD------ 708 TL +S + +IK E I+++ + L +E + H + ED + R Sbjct: 374 TLWNLSSHD----SIKME-IVDHALHALT--DEVIIPHSGWE-REPNEDCKPRHIEWESV 425 Query: 709 LVRLHGGLKPLASLLNNTDNKERLAAVTGAIWKC--SISKENVTKFREYKAIETLVGLLT 766 L G L+ ++S ++ + +L G + + E K + K +E V LL Sbjct: 426 LTNTAGCLRNVSS--ERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLR 483 Query: 767 DQPEEVLVNVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAV 826 + +V + A E QE P V G + A K G + Sbjct: 484 NLSYQVHREIPQA--ERYQE------------AAPNVANNTGPHAASCFGAKKGKGKKPI 529 Query: 827 EPESMMIID---------------RLDGVRLLWSLLK-NPHPDVKASAAWALCPCIKNAK 870 E + +D + + VR+ SLLK + P + ++A A+ Sbjct: 530 EDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRW 589 Query: 871 DAGEMVRSFV---GGLELIVNLLKSDNKEVLASVCAAITNIAKDQENLAVITDHGVVPLL 927 G +RS + L I +LL ++++ V+ + A+ N+A D N +I H + L+ Sbjct: 590 TYGRYIRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLV 649 Query: 928 SKLANTNNN 936 L N Sbjct: 650 KNLPGGQQN 658 Score = 35.8 bits (81), Expect = 0.22 Identities = 35/170 (20%), Positives = 77/170 (45%), Gaps = 28/170 (16%) Query: 524 NPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVA--KFKRARRVVRQHGGITKL 581 N +++ ++ L G+P++V +LD P K + A + N++ + + + ++ G+ L Sbjct: 296 NDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPAL 355 Query: 582 VALLDCAHDSTKPAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLL 641 V L L +ARD+++ LW+ S + K + ++ L Sbjct: 356 VRL--------------LRKARDMDLTEVITGTLWNLSSHDSIK--------MEIVDHAL 393 Query: 642 KTSHENMLIPVVGTLQECASEENYRAAIKAERIIEN---LVKNLNSENEQ 688 + ++IP G +E +E+ I+ E ++ N ++N++SE + Sbjct: 394 HALTDEVIIPHSGWERE-PNEDCKPRHIEWESVLTNTAGCLRNVSSERSE 442 Score = 32.0 bits (71), Expect = 3.1 Identities = 33/130 (25%), Positives = 55/130 (42%), Gaps = 16/130 (12%) Query: 625 KEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECASEENYRAAIKAERIIENLVKNL-- 682 + A+R+ + +A LL HE ++ G L+ A + + I + I NLVKNL Sbjct: 596 RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELI-GKHAIPNLVKNLPG 654 Query: 683 --NSENEQLQEHCAMAIYQ-----CAEDKETRDLVRLHGGLKPLASLLNNTDNKER---- 731 + + E ++I AE+ E +R G++ L L+N + N+ Sbjct: 655 GQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLV-LINKSGNRSEKEVR 713 Query: 732 -LAAVTGAIW 740 A V IW Sbjct: 714 AAALVLQTIW 723 Score = 30.8 bits (68), Expect = 7.0 Identities = 31/128 (24%), Positives = 53/128 (41%), Gaps = 6/128 (4%) Query: 721 SLLNNTDNKERLAAVTGAIWKCSISKENVTKF-----REYKAIETLVGLLTDQPEEVLVN 775 SLL + L A GAI + ++ R+ KA+ + LLT++ E V+ Sbjct: 563 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKA 622 Query: 776 VVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAVEPESMMIID 835 GAL + N+ ++ K I LV L G Q N ++ + + +I + Sbjct: 623 ASGALRNLAVDARNKELIGK-HAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 681 Query: 836 RLDGVRLL 843 L+ + L Sbjct: 682 NLEAAKKL 689 >gi|146231994 catenin, delta 1 isoform 3A [Homo sapiens] Length = 832 Score = 52.0 bits (123), Expect = 3e-06 Identities = 100/429 (23%), Positives = 174/429 (40%), Gaps = 66/429 (15%) Query: 537 LPIMVNILDSPHKSLKCLAAETIANVA-KFKRARRVVRQHGGITKLVALLDCAHDSTKPA 595 LP ++ +L ++K AA + ++ + + + VR+ GI LV LLD Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLD--------- 317 Query: 596 QSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVV-G 654 + ++V + CGAL S + NK AI+ G+P L RLL+ + + L V+ G Sbjct: 318 ----HPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITG 373 Query: 655 TLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKETRD------ 708 TL +S + +IK E I+++ + L +E + H + ED + R Sbjct: 374 TLWNLSSHD----SIKME-IVDHALHALT--DEVIIPHSGWE-REPNEDCKPRHIEWESV 425 Query: 709 LVRLHGGLKPLASLLNNTDNKERLAAVTGAIWKC--SISKENVTKFREYKAIETLVGLLT 766 L G L+ ++S ++ + +L G + + E K + K +E V LL Sbjct: 426 LTNTAGCLRNVSS--ERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLR 483 Query: 767 DQPEEVLVNVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAV 826 + +V + A E QE P V G + A K G + Sbjct: 484 NLSYQVHREIPQA--ERYQE------------AAPNVANNTGPHAASCFGAKKGKGKKPI 529 Query: 827 EPESMMIID---------------RLDGVRLLWSLLK-NPHPDVKASAAWALCPCIKNAK 870 E + +D + + VR+ SLLK + P + ++A A+ Sbjct: 530 EDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRW 589 Query: 871 DAGEMVRSFV---GGLELIVNLLKSDNKEVLASVCAAITNIAKDQENLAVITDHGVVPLL 927 G +RS + L I +LL ++++ V+ + A+ N+A D N +I H + L+ Sbjct: 590 TYGRYIRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLV 649 Query: 928 SKLANTNNN 936 L N Sbjct: 650 KNLPGGQQN 658 Score = 35.8 bits (81), Expect = 0.22 Identities = 35/170 (20%), Positives = 77/170 (45%), Gaps = 28/170 (16%) Query: 524 NPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVA--KFKRARRVVRQHGGITKL 581 N +++ ++ L G+P++V +LD P K + A + N++ + + + ++ G+ L Sbjct: 296 NDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPAL 355 Query: 582 VALLDCAHDSTKPAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLL 641 V L L +ARD+++ LW+ S + K + ++ L Sbjct: 356 VRL--------------LRKARDMDLTEVITGTLWNLSSHDSIK--------MEIVDHAL 393 Query: 642 KTSHENMLIPVVGTLQECASEENYRAAIKAERIIEN---LVKNLNSENEQ 688 + ++IP G +E +E+ I+ E ++ N ++N++SE + Sbjct: 394 HALTDEVIIPHSGWERE-PNEDCKPRHIEWESVLTNTAGCLRNVSSERSE 442 Score = 32.0 bits (71), Expect = 3.1 Identities = 33/130 (25%), Positives = 55/130 (42%), Gaps = 16/130 (12%) Query: 625 KEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECASEENYRAAIKAERIIENLVKNL-- 682 + A+R+ + +A LL HE ++ G L+ A + + I + I NLVKNL Sbjct: 596 RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELI-GKHAIPNLVKNLPG 654 Query: 683 --NSENEQLQEHCAMAIYQ-----CAEDKETRDLVRLHGGLKPLASLLNNTDNKER---- 731 + + E ++I AE+ E +R G++ L L+N + N+ Sbjct: 655 GQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLV-LINKSGNRSEKEVR 713 Query: 732 -LAAVTGAIW 740 A V IW Sbjct: 714 AAALVLQTIW 723 Score = 30.8 bits (68), Expect = 7.0 Identities = 31/128 (24%), Positives = 53/128 (41%), Gaps = 6/128 (4%) Query: 721 SLLNNTDNKERLAAVTGAIWKCSISKENVTKF-----REYKAIETLVGLLTDQPEEVLVN 775 SLL + L A GAI + ++ R+ KA+ + LLT++ E V+ Sbjct: 563 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKA 622 Query: 776 VVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAVEPESMMIID 835 GAL + N+ ++ K I LV L G Q N ++ + + +I + Sbjct: 623 ASGALRNLAVDARNKELIGK-HAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 681 Query: 836 RLDGVRLL 843 L+ + L Sbjct: 682 NLEAAKKL 689 >gi|146231946 catenin, delta 1 isoform 3B [Homo sapiens] Length = 840 Score = 52.0 bits (123), Expect = 3e-06 Identities = 100/429 (23%), Positives = 174/429 (40%), Gaps = 66/429 (15%) Query: 537 LPIMVNILDSPHKSLKCLAAETIANVA-KFKRARRVVRQHGGITKLVALLDCAHDSTKPA 595 LP ++ +L ++K AA + ++ + + + VR+ GI LV LLD Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLD--------- 317 Query: 596 QSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVV-G 654 + ++V + CGAL S + NK AI+ G+P L RLL+ + + L V+ G Sbjct: 318 ----HPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITG 373 Query: 655 TLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKETRD------ 708 TL +S + +IK E I+++ + L +E + H + ED + R Sbjct: 374 TLWNLSSHD----SIKME-IVDHALHALT--DEVIIPHSGWE-REPNEDCKPRHIEWESV 425 Query: 709 LVRLHGGLKPLASLLNNTDNKERLAAVTGAIWKC--SISKENVTKFREYKAIETLVGLLT 766 L G L+ ++S ++ + +L G + + E K + K +E V LL Sbjct: 426 LTNTAGCLRNVSS--ERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLR 483 Query: 767 DQPEEVLVNVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAV 826 + +V + A E QE P V G + A K G + Sbjct: 484 NLSYQVHREIPQA--ERYQE------------AAPNVANNTGPHAASCFGAKKGKGKKPI 529 Query: 827 EPESMMIID---------------RLDGVRLLWSLLK-NPHPDVKASAAWALCPCIKNAK 870 E + +D + + VR+ SLLK + P + ++A A+ Sbjct: 530 EDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRW 589 Query: 871 DAGEMVRSFV---GGLELIVNLLKSDNKEVLASVCAAITNIAKDQENLAVITDHGVVPLL 927 G +RS + L I +LL ++++ V+ + A+ N+A D N +I H + L+ Sbjct: 590 TYGRYIRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLV 649 Query: 928 SKLANTNNN 936 L N Sbjct: 650 KNLPGGQQN 658 Score = 35.8 bits (81), Expect = 0.22 Identities = 35/170 (20%), Positives = 77/170 (45%), Gaps = 28/170 (16%) Query: 524 NPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVA--KFKRARRVVRQHGGITKL 581 N +++ ++ L G+P++V +LD P K + A + N++ + + + ++ G+ L Sbjct: 296 NDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPAL 355 Query: 582 VALLDCAHDSTKPAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLL 641 V L L +ARD+++ LW+ S + K + ++ L Sbjct: 356 VRL--------------LRKARDMDLTEVITGTLWNLSSHDSIK--------MEIVDHAL 393 Query: 642 KTSHENMLIPVVGTLQECASEENYRAAIKAERIIEN---LVKNLNSENEQ 688 + ++IP G +E +E+ I+ E ++ N ++N++SE + Sbjct: 394 HALTDEVIIPHSGWERE-PNEDCKPRHIEWESVLTNTAGCLRNVSSERSE 442 Score = 32.0 bits (71), Expect = 3.1 Identities = 33/130 (25%), Positives = 55/130 (42%), Gaps = 16/130 (12%) Query: 625 KEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECASEENYRAAIKAERIIENLVKNL-- 682 + A+R+ + +A LL HE ++ G L+ A + + I + I NLVKNL Sbjct: 596 RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELI-GKHAIPNLVKNLPG 654 Query: 683 --NSENEQLQEHCAMAIYQ-----CAEDKETRDLVRLHGGLKPLASLLNNTDNKER---- 731 + + E ++I AE+ E +R G++ L L+N + N+ Sbjct: 655 GQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLV-LINKSGNRSEKEVR 713 Query: 732 -LAAVTGAIW 740 A V IW Sbjct: 714 AAALVLQTIW 723 Score = 30.8 bits (68), Expect = 7.0 Identities = 31/128 (24%), Positives = 53/128 (41%), Gaps = 6/128 (4%) Query: 721 SLLNNTDNKERLAAVTGAIWKCSISKENVTKF-----REYKAIETLVGLLTDQPEEVLVN 775 SLL + L A GAI + ++ R+ KA+ + LLT++ E V+ Sbjct: 563 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKA 622 Query: 776 VVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAVEPESMMIID 835 GAL + N+ ++ K I LV L G Q N ++ + + +I + Sbjct: 623 ASGALRNLAVDARNKELIGK-HAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 681 Query: 836 RLDGVRLL 843 L+ + L Sbjct: 682 NLEAAKKL 689 >gi|146231991 catenin, delta 1 isoform 3AB [Homo sapiens] Length = 861 Score = 52.0 bits (123), Expect = 3e-06 Identities = 100/429 (23%), Positives = 174/429 (40%), Gaps = 66/429 (15%) Query: 537 LPIMVNILDSPHKSLKCLAAETIANVA-KFKRARRVVRQHGGITKLVALLDCAHDSTKPA 595 LP ++ +L ++K AA + ++ + + + VR+ GI LV LLD Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLD--------- 317 Query: 596 QSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVV-G 654 + ++V + CGAL S + NK AI+ G+P L RLL+ + + L V+ G Sbjct: 318 ----HPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITG 373 Query: 655 TLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKETRD------ 708 TL +S + +IK E I+++ + L +E + H + ED + R Sbjct: 374 TLWNLSSHD----SIKME-IVDHALHALT--DEVIIPHSGWE-REPNEDCKPRHIEWESV 425 Query: 709 LVRLHGGLKPLASLLNNTDNKERLAAVTGAIWKC--SISKENVTKFREYKAIETLVGLLT 766 L G L+ ++S ++ + +L G + + E K + K +E V LL Sbjct: 426 LTNTAGCLRNVSS--ERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLR 483 Query: 767 DQPEEVLVNVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAV 826 + +V + A E QE P V G + A K G + Sbjct: 484 NLSYQVHREIPQA--ERYQE------------AAPNVANNTGPHAASCFGAKKGKGKKPI 529 Query: 827 EPESMMIID---------------RLDGVRLLWSLLK-NPHPDVKASAAWALCPCIKNAK 870 E + +D + + VR+ SLLK + P + ++A A+ Sbjct: 530 EDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRW 589 Query: 871 DAGEMVRSFV---GGLELIVNLLKSDNKEVLASVCAAITNIAKDQENLAVITDHGVVPLL 927 G +RS + L I +LL ++++ V+ + A+ N+A D N +I H + L+ Sbjct: 590 TYGRYIRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLV 649 Query: 928 SKLANTNNN 936 L N Sbjct: 650 KNLPGGQQN 658 Score = 35.8 bits (81), Expect = 0.22 Identities = 35/170 (20%), Positives = 77/170 (45%), Gaps = 28/170 (16%) Query: 524 NPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVA--KFKRARRVVRQHGGITKL 581 N +++ ++ L G+P++V +LD P K + A + N++ + + + ++ G+ L Sbjct: 296 NDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPAL 355 Query: 582 VALLDCAHDSTKPAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLL 641 V L L +ARD+++ LW+ S + K + ++ L Sbjct: 356 VRL--------------LRKARDMDLTEVITGTLWNLSSHDSIK--------MEIVDHAL 393 Query: 642 KTSHENMLIPVVGTLQECASEENYRAAIKAERIIEN---LVKNLNSENEQ 688 + ++IP G +E +E+ I+ E ++ N ++N++SE + Sbjct: 394 HALTDEVIIPHSGWERE-PNEDCKPRHIEWESVLTNTAGCLRNVSSERSE 442 Score = 32.0 bits (71), Expect = 3.1 Identities = 33/130 (25%), Positives = 55/130 (42%), Gaps = 16/130 (12%) Query: 625 KEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECASEENYRAAIKAERIIENLVKNL-- 682 + A+R+ + +A LL HE ++ G L+ A + + I + I NLVKNL Sbjct: 596 RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELI-GKHAIPNLVKNLPG 654 Query: 683 --NSENEQLQEHCAMAIYQ-----CAEDKETRDLVRLHGGLKPLASLLNNTDNKER---- 731 + + E ++I AE+ E +R G++ L L+N + N+ Sbjct: 655 GQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLV-LINKSGNRSEKEVR 713 Query: 732 -LAAVTGAIW 740 A V IW Sbjct: 714 AAALVLQTIW 723 Score = 30.8 bits (68), Expect = 7.0 Identities = 31/128 (24%), Positives = 53/128 (41%), Gaps = 6/128 (4%) Query: 721 SLLNNTDNKERLAAVTGAIWKCSISKENVTKF-----REYKAIETLVGLLTDQPEEVLVN 775 SLL + L A GAI + ++ R+ KA+ + LLT++ E V+ Sbjct: 563 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKA 622 Query: 776 VVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAVEPESMMIID 835 GAL + N+ ++ K I LV L G Q N ++ + + +I + Sbjct: 623 ASGALRNLAVDARNKELIGK-HAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 681 Query: 836 RLDGVRLL 843 L+ + L Sbjct: 682 NLEAAKKL 689 >gi|146231942 catenin, delta 1 isoform 1A [Homo sapiens] Length = 933 Score = 52.0 bits (123), Expect = 3e-06 Identities = 100/429 (23%), Positives = 174/429 (40%), Gaps = 66/429 (15%) Query: 537 LPIMVNILDSPHKSLKCLAAETIANVA-KFKRARRVVRQHGGITKLVALLDCAHDSTKPA 595 LP ++ +L ++K AA + ++ + + + VR+ GI LV LLD Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLD--------- 418 Query: 596 QSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVV-G 654 + ++V + CGAL S + NK AI+ G+P L RLL+ + + L V+ G Sbjct: 419 ----HPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITG 474 Query: 655 TLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKETRD------ 708 TL +S + +IK E I+++ + L +E + H + ED + R Sbjct: 475 TLWNLSSHD----SIKME-IVDHALHALT--DEVIIPHSGWE-REPNEDCKPRHIEWESV 526 Query: 709 LVRLHGGLKPLASLLNNTDNKERLAAVTGAIWKC--SISKENVTKFREYKAIETLVGLLT 766 L G L+ ++S ++ + +L G + + E K + K +E V LL Sbjct: 527 LTNTAGCLRNVSS--ERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLR 584 Query: 767 DQPEEVLVNVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAV 826 + +V + A E QE P V G + A K G + Sbjct: 585 NLSYQVHREIPQA--ERYQE------------AAPNVANNTGPHAASCFGAKKGKGKKPI 630 Query: 827 EPESMMIID---------------RLDGVRLLWSLLK-NPHPDVKASAAWALCPCIKNAK 870 E + +D + + VR+ SLLK + P + ++A A+ Sbjct: 631 EDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRW 690 Query: 871 DAGEMVRSFV---GGLELIVNLLKSDNKEVLASVCAAITNIAKDQENLAVITDHGVVPLL 927 G +RS + L I +LL ++++ V+ + A+ N+A D N +I H + L+ Sbjct: 691 TYGRYIRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLV 750 Query: 928 SKLANTNNN 936 L N Sbjct: 751 KNLPGGQQN 759 Score = 35.8 bits (81), Expect = 0.22 Identities = 35/170 (20%), Positives = 77/170 (45%), Gaps = 28/170 (16%) Query: 524 NPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVA--KFKRARRVVRQHGGITKL 581 N +++ ++ L G+P++V +LD P K + A + N++ + + + ++ G+ L Sbjct: 397 NDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPAL 456 Query: 582 VALLDCAHDSTKPAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLL 641 V L L +ARD+++ LW+ S + K + ++ L Sbjct: 457 VRL--------------LRKARDMDLTEVITGTLWNLSSHDSIK--------MEIVDHAL 494 Query: 642 KTSHENMLIPVVGTLQECASEENYRAAIKAERIIEN---LVKNLNSENEQ 688 + ++IP G +E +E+ I+ E ++ N ++N++SE + Sbjct: 495 HALTDEVIIPHSGWERE-PNEDCKPRHIEWESVLTNTAGCLRNVSSERSE 543 Score = 32.0 bits (71), Expect = 3.1 Identities = 33/130 (25%), Positives = 55/130 (42%), Gaps = 16/130 (12%) Query: 625 KEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECASEENYRAAIKAERIIENLVKNL-- 682 + A+R+ + +A LL HE ++ G L+ A + + I + I NLVKNL Sbjct: 697 RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELI-GKHAIPNLVKNLPG 755 Query: 683 --NSENEQLQEHCAMAIYQ-----CAEDKETRDLVRLHGGLKPLASLLNNTDNKER---- 731 + + E ++I AE+ E +R G++ L L+N + N+ Sbjct: 756 GQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLV-LINKSGNRSEKEVR 814 Query: 732 -LAAVTGAIW 740 A V IW Sbjct: 815 AAALVLQTIW 824 Score = 30.8 bits (68), Expect = 7.0 Identities = 31/128 (24%), Positives = 53/128 (41%), Gaps = 6/128 (4%) Query: 721 SLLNNTDNKERLAAVTGAIWKCSISKENVTKF-----REYKAIETLVGLLTDQPEEVLVN 775 SLL + L A GAI + ++ R+ KA+ + LLT++ E V+ Sbjct: 664 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKA 723 Query: 776 VVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAVEPESMMIID 835 GAL + N+ ++ K I LV L G Q N ++ + + +I + Sbjct: 724 ASGALRNLAVDARNKELIGK-HAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 782 Query: 836 RLDGVRLL 843 L+ + L Sbjct: 783 NLEAAKKL 790 >gi|146231968 catenin, delta 1 isoform 1A [Homo sapiens] Length = 933 Score = 52.0 bits (123), Expect = 3e-06 Identities = 100/429 (23%), Positives = 174/429 (40%), Gaps = 66/429 (15%) Query: 537 LPIMVNILDSPHKSLKCLAAETIANVA-KFKRARRVVRQHGGITKLVALLDCAHDSTKPA 595 LP ++ +L ++K AA + ++ + + + VR+ GI LV LLD Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLD--------- 418 Query: 596 QSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVV-G 654 + ++V + CGAL S + NK AI+ G+P L RLL+ + + L V+ G Sbjct: 419 ----HPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITG 474 Query: 655 TLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKETRD------ 708 TL +S + +IK E I+++ + L +E + H + ED + R Sbjct: 475 TLWNLSSHD----SIKME-IVDHALHALT--DEVIIPHSGWE-REPNEDCKPRHIEWESV 526 Query: 709 LVRLHGGLKPLASLLNNTDNKERLAAVTGAIWKC--SISKENVTKFREYKAIETLVGLLT 766 L G L+ ++S ++ + +L G + + E K + K +E V LL Sbjct: 527 LTNTAGCLRNVSS--ERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLR 584 Query: 767 DQPEEVLVNVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAV 826 + +V + A E QE P V G + A K G + Sbjct: 585 NLSYQVHREIPQA--ERYQE------------AAPNVANNTGPHAASCFGAKKGKGKKPI 630 Query: 827 EPESMMIID---------------RLDGVRLLWSLLK-NPHPDVKASAAWALCPCIKNAK 870 E + +D + + VR+ SLLK + P + ++A A+ Sbjct: 631 EDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRW 690 Query: 871 DAGEMVRSFV---GGLELIVNLLKSDNKEVLASVCAAITNIAKDQENLAVITDHGVVPLL 927 G +RS + L I +LL ++++ V+ + A+ N+A D N +I H + L+ Sbjct: 691 TYGRYIRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLV 750 Query: 928 SKLANTNNN 936 L N Sbjct: 751 KNLPGGQQN 759 Score = 35.8 bits (81), Expect = 0.22 Identities = 35/170 (20%), Positives = 77/170 (45%), Gaps = 28/170 (16%) Query: 524 NPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVA--KFKRARRVVRQHGGITKL 581 N +++ ++ L G+P++V +LD P K + A + N++ + + + ++ G+ L Sbjct: 397 NDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPAL 456 Query: 582 VALLDCAHDSTKPAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLL 641 V L L +ARD+++ LW+ S + K + ++ L Sbjct: 457 VRL--------------LRKARDMDLTEVITGTLWNLSSHDSIK--------MEIVDHAL 494 Query: 642 KTSHENMLIPVVGTLQECASEENYRAAIKAERIIEN---LVKNLNSENEQ 688 + ++IP G +E +E+ I+ E ++ N ++N++SE + Sbjct: 495 HALTDEVIIPHSGWERE-PNEDCKPRHIEWESVLTNTAGCLRNVSSERSE 543 Score = 32.0 bits (71), Expect = 3.1 Identities = 33/130 (25%), Positives = 55/130 (42%), Gaps = 16/130 (12%) Query: 625 KEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECASEENYRAAIKAERIIENLVKNL-- 682 + A+R+ + +A LL HE ++ G L+ A + + I + I NLVKNL Sbjct: 697 RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELI-GKHAIPNLVKNLPG 755 Query: 683 --NSENEQLQEHCAMAIYQ-----CAEDKETRDLVRLHGGLKPLASLLNNTDNKER---- 731 + + E ++I AE+ E +R G++ L L+N + N+ Sbjct: 756 GQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLV-LINKSGNRSEKEVR 814 Query: 732 -LAAVTGAIW 740 A V IW Sbjct: 815 AAALVLQTIW 824 Score = 30.8 bits (68), Expect = 7.0 Identities = 31/128 (24%), Positives = 53/128 (41%), Gaps = 6/128 (4%) Query: 721 SLLNNTDNKERLAAVTGAIWKCSISKENVTKF-----REYKAIETLVGLLTDQPEEVLVN 775 SLL + L A GAI + ++ R+ KA+ + LLT++ E V+ Sbjct: 664 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKA 723 Query: 776 VVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAVEPESMMIID 835 GAL + N+ ++ K I LV L G Q N ++ + + +I + Sbjct: 724 ASGALRNLAVDARNKELIGK-HAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 782 Query: 836 RLDGVRLL 843 L+ + L Sbjct: 783 NLEAAKKL 790 >gi|146231938 catenin, delta 1 isoform 1A [Homo sapiens] Length = 933 Score = 52.0 bits (123), Expect = 3e-06 Identities = 100/429 (23%), Positives = 174/429 (40%), Gaps = 66/429 (15%) Query: 537 LPIMVNILDSPHKSLKCLAAETIANVA-KFKRARRVVRQHGGITKLVALLDCAHDSTKPA 595 LP ++ +L ++K AA + ++ + + + VR+ GI LV LLD Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLD--------- 418 Query: 596 QSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVV-G 654 + ++V + CGAL S + NK AI+ G+P L RLL+ + + L V+ G Sbjct: 419 ----HPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITG 474 Query: 655 TLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKETRD------ 708 TL +S + +IK E I+++ + L +E + H + ED + R Sbjct: 475 TLWNLSSHD----SIKME-IVDHALHALT--DEVIIPHSGWE-REPNEDCKPRHIEWESV 526 Query: 709 LVRLHGGLKPLASLLNNTDNKERLAAVTGAIWKC--SISKENVTKFREYKAIETLVGLLT 766 L G L+ ++S ++ + +L G + + E K + K +E V LL Sbjct: 527 LTNTAGCLRNVSS--ERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLR 584 Query: 767 DQPEEVLVNVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAV 826 + +V + A E QE P V G + A K G + Sbjct: 585 NLSYQVHREIPQA--ERYQE------------AAPNVANNTGPHAASCFGAKKGKGKKPI 630 Query: 827 EPESMMIID---------------RLDGVRLLWSLLK-NPHPDVKASAAWALCPCIKNAK 870 E + +D + + VR+ SLLK + P + ++A A+ Sbjct: 631 EDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRW 690 Query: 871 DAGEMVRSFV---GGLELIVNLLKSDNKEVLASVCAAITNIAKDQENLAVITDHGVVPLL 927 G +RS + L I +LL ++++ V+ + A+ N+A D N +I H + L+ Sbjct: 691 TYGRYIRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLV 750 Query: 928 SKLANTNNN 936 L N Sbjct: 751 KNLPGGQQN 759 Score = 35.8 bits (81), Expect = 0.22 Identities = 35/170 (20%), Positives = 77/170 (45%), Gaps = 28/170 (16%) Query: 524 NPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVA--KFKRARRVVRQHGGITKL 581 N +++ ++ L G+P++V +LD P K + A + N++ + + + ++ G+ L Sbjct: 397 NDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPAL 456 Query: 582 VALLDCAHDSTKPAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLL 641 V L L +ARD+++ LW+ S + K + ++ L Sbjct: 457 VRL--------------LRKARDMDLTEVITGTLWNLSSHDSIK--------MEIVDHAL 494 Query: 642 KTSHENMLIPVVGTLQECASEENYRAAIKAERIIEN---LVKNLNSENEQ 688 + ++IP G +E +E+ I+ E ++ N ++N++SE + Sbjct: 495 HALTDEVIIPHSGWERE-PNEDCKPRHIEWESVLTNTAGCLRNVSSERSE 543 Score = 32.0 bits (71), Expect = 3.1 Identities = 33/130 (25%), Positives = 55/130 (42%), Gaps = 16/130 (12%) Query: 625 KEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECASEENYRAAIKAERIIENLVKNL-- 682 + A+R+ + +A LL HE ++ G L+ A + + I + I NLVKNL Sbjct: 697 RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELI-GKHAIPNLVKNLPG 755 Query: 683 --NSENEQLQEHCAMAIYQ-----CAEDKETRDLVRLHGGLKPLASLLNNTDNKER---- 731 + + E ++I AE+ E +R G++ L L+N + N+ Sbjct: 756 GQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLV-LINKSGNRSEKEVR 814 Query: 732 -LAAVTGAIW 740 A V IW Sbjct: 815 AAALVLQTIW 824 Score = 30.8 bits (68), Expect = 7.0 Identities = 31/128 (24%), Positives = 53/128 (41%), Gaps = 6/128 (4%) Query: 721 SLLNNTDNKERLAAVTGAIWKCSISKENVTKF-----REYKAIETLVGLLTDQPEEVLVN 775 SLL + L A GAI + ++ R+ KA+ + LLT++ E V+ Sbjct: 664 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKA 723 Query: 776 VVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAVEPESMMIID 835 GAL + N+ ++ K I LV L G Q N ++ + + +I + Sbjct: 724 ASGALRNLAVDARNKELIGK-HAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 782 Query: 836 RLDGVRLL 843 L+ + L Sbjct: 783 NLEAAKKL 790 >gi|10835010 catenin, delta 1 isoform 1B [Homo sapiens] Length = 941 Score = 52.0 bits (123), Expect = 3e-06 Identities = 100/429 (23%), Positives = 174/429 (40%), Gaps = 66/429 (15%) Query: 537 LPIMVNILDSPHKSLKCLAAETIANVA-KFKRARRVVRQHGGITKLVALLDCAHDSTKPA 595 LP ++ +L ++K AA + ++ + + + VR+ GI LV LLD Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLD--------- 418 Query: 596 QSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVV-G 654 + ++V + CGAL S + NK AI+ G+P L RLL+ + + L V+ G Sbjct: 419 ----HPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITG 474 Query: 655 TLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKETRD------ 708 TL +S + +IK E I+++ + L +E + H + ED + R Sbjct: 475 TLWNLSSHD----SIKME-IVDHALHALT--DEVIIPHSGWE-REPNEDCKPRHIEWESV 526 Query: 709 LVRLHGGLKPLASLLNNTDNKERLAAVTGAIWKC--SISKENVTKFREYKAIETLVGLLT 766 L G L+ ++S ++ + +L G + + E K + K +E V LL Sbjct: 527 LTNTAGCLRNVSS--ERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLR 584 Query: 767 DQPEEVLVNVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAV 826 + +V + A E QE P V G + A K G + Sbjct: 585 NLSYQVHREIPQA--ERYQE------------AAPNVANNTGPHAASCFGAKKGKGKKPI 630 Query: 827 EPESMMIID---------------RLDGVRLLWSLLK-NPHPDVKASAAWALCPCIKNAK 870 E + +D + + VR+ SLLK + P + ++A A+ Sbjct: 631 EDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRW 690 Query: 871 DAGEMVRSFV---GGLELIVNLLKSDNKEVLASVCAAITNIAKDQENLAVITDHGVVPLL 927 G +RS + L I +LL ++++ V+ + A+ N+A D N +I H + L+ Sbjct: 691 TYGRYIRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLV 750 Query: 928 SKLANTNNN 936 L N Sbjct: 751 KNLPGGQQN 759 Score = 35.8 bits (81), Expect = 0.22 Identities = 35/170 (20%), Positives = 77/170 (45%), Gaps = 28/170 (16%) Query: 524 NPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVA--KFKRARRVVRQHGGITKL 581 N +++ ++ L G+P++V +LD P K + A + N++ + + + ++ G+ L Sbjct: 397 NDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPAL 456 Query: 582 VALLDCAHDSTKPAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLL 641 V L L +ARD+++ LW+ S + K + ++ L Sbjct: 457 VRL--------------LRKARDMDLTEVITGTLWNLSSHDSIK--------MEIVDHAL 494 Query: 642 KTSHENMLIPVVGTLQECASEENYRAAIKAERIIEN---LVKNLNSENEQ 688 + ++IP G +E +E+ I+ E ++ N ++N++SE + Sbjct: 495 HALTDEVIIPHSGWERE-PNEDCKPRHIEWESVLTNTAGCLRNVSSERSE 543 Score = 32.0 bits (71), Expect = 3.1 Identities = 33/130 (25%), Positives = 55/130 (42%), Gaps = 16/130 (12%) Query: 625 KEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECASEENYRAAIKAERIIENLVKNL-- 682 + A+R+ + +A LL HE ++ G L+ A + + I + I NLVKNL Sbjct: 697 RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELI-GKHAIPNLVKNLPG 755 Query: 683 --NSENEQLQEHCAMAIYQ-----CAEDKETRDLVRLHGGLKPLASLLNNTDNKER---- 731 + + E ++I AE+ E +R G++ L L+N + N+ Sbjct: 756 GQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLV-LINKSGNRSEKEVR 814 Query: 732 -LAAVTGAIW 740 A V IW Sbjct: 815 AAALVLQTIW 824 Score = 30.8 bits (68), Expect = 7.0 Identities = 31/128 (24%), Positives = 53/128 (41%), Gaps = 6/128 (4%) Query: 721 SLLNNTDNKERLAAVTGAIWKCSISKENVTKF-----REYKAIETLVGLLTDQPEEVLVN 775 SLL + L A GAI + ++ R+ KA+ + LLT++ E V+ Sbjct: 664 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKA 723 Query: 776 VVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAVEPESMMIID 835 GAL + N+ ++ K I LV L G Q N ++ + + +I + Sbjct: 724 ASGALRNLAVDARNKELIGK-HAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 782 Query: 836 RLDGVRLL 843 L+ + L Sbjct: 783 NLEAAKKL 790 >gi|146231962 catenin, delta 1 isoform 1AB [Homo sapiens] Length = 962 Score = 52.0 bits (123), Expect = 3e-06 Identities = 100/429 (23%), Positives = 174/429 (40%), Gaps = 66/429 (15%) Query: 537 LPIMVNILDSPHKSLKCLAAETIANVA-KFKRARRVVRQHGGITKLVALLDCAHDSTKPA 595 LP ++ +L ++K AA + ++ + + + VR+ GI LV LLD Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLD--------- 418 Query: 596 QSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVV-G 654 + ++V + CGAL S + NK AI+ G+P L RLL+ + + L V+ G Sbjct: 419 ----HPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITG 474 Query: 655 TLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKETRD------ 708 TL +S + +IK E I+++ + L +E + H + ED + R Sbjct: 475 TLWNLSSHD----SIKME-IVDHALHALT--DEVIIPHSGWE-REPNEDCKPRHIEWESV 526 Query: 709 LVRLHGGLKPLASLLNNTDNKERLAAVTGAIWKC--SISKENVTKFREYKAIETLVGLLT 766 L G L+ ++S ++ + +L G + + E K + K +E V LL Sbjct: 527 LTNTAGCLRNVSS--ERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLR 584 Query: 767 DQPEEVLVNVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAV 826 + +V + A E QE P V G + A K G + Sbjct: 585 NLSYQVHREIPQA--ERYQE------------AAPNVANNTGPHAASCFGAKKGKGKKPI 630 Query: 827 EPESMMIID---------------RLDGVRLLWSLLK-NPHPDVKASAAWALCPCIKNAK 870 E + +D + + VR+ SLLK + P + ++A A+ Sbjct: 631 EDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRW 690 Query: 871 DAGEMVRSFV---GGLELIVNLLKSDNKEVLASVCAAITNIAKDQENLAVITDHGVVPLL 927 G +RS + L I +LL ++++ V+ + A+ N+A D N +I H + L+ Sbjct: 691 TYGRYIRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLV 750 Query: 928 SKLANTNNN 936 L N Sbjct: 751 KNLPGGQQN 759 Score = 35.8 bits (81), Expect = 0.22 Identities = 35/170 (20%), Positives = 77/170 (45%), Gaps = 28/170 (16%) Query: 524 NPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVA--KFKRARRVVRQHGGITKL 581 N +++ ++ L G+P++V +LD P K + A + N++ + + + ++ G+ L Sbjct: 397 NDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPAL 456 Query: 582 VALLDCAHDSTKPAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLL 641 V L L +ARD+++ LW+ S + K + ++ L Sbjct: 457 VRL--------------LRKARDMDLTEVITGTLWNLSSHDSIK--------MEIVDHAL 494 Query: 642 KTSHENMLIPVVGTLQECASEENYRAAIKAERIIEN---LVKNLNSENEQ 688 + ++IP G +E +E+ I+ E ++ N ++N++SE + Sbjct: 495 HALTDEVIIPHSGWERE-PNEDCKPRHIEWESVLTNTAGCLRNVSSERSE 543 Score = 32.0 bits (71), Expect = 3.1 Identities = 33/130 (25%), Positives = 55/130 (42%), Gaps = 16/130 (12%) Query: 625 KEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECASEENYRAAIKAERIIENLVKNL-- 682 + A+R+ + +A LL HE ++ G L+ A + + I + I NLVKNL Sbjct: 697 RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELI-GKHAIPNLVKNLPG 755 Query: 683 --NSENEQLQEHCAMAIYQ-----CAEDKETRDLVRLHGGLKPLASLLNNTDNKER---- 731 + + E ++I AE+ E +R G++ L L+N + N+ Sbjct: 756 GQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLV-LINKSGNRSEKEVR 814 Query: 732 -LAAVTGAIW 740 A V IW Sbjct: 815 AAALVLQTIW 824 Score = 30.8 bits (68), Expect = 7.0 Identities = 31/128 (24%), Positives = 53/128 (41%), Gaps = 6/128 (4%) Query: 721 SLLNNTDNKERLAAVTGAIWKCSISKENVTKF-----REYKAIETLVGLLTDQPEEVLVN 775 SLL + L A GAI + ++ R+ KA+ + LLT++ E V+ Sbjct: 664 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKA 723 Query: 776 VVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAVEPESMMIID 835 GAL + N+ ++ K I LV L G Q N ++ + + +I + Sbjct: 724 ASGALRNLAVDARNKELIGK-HAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 782 Query: 836 RLDGVRLL 843 L+ + L Sbjct: 783 NLEAAKKL 790 >gi|53829376 plakophilin 4 isoform b [Homo sapiens] Length = 1149 Score = 50.1 bits (118), Expect = 1e-05 Identities = 119/508 (23%), Positives = 188/508 (37%), Gaps = 90/508 (17%) Query: 537 LPIMVNILDSPHKSLKCLAAETIANVA-KFKRARRVVRQHGGITKLVALLDCAHDSTKPA 595 LP ++++L S++ AA + ++ + + V + GGI LV LLD Sbjct: 530 LPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRLGGIKHLVDLLD--------- 580 Query: 596 QSSLYEARDVEVARCGALALWSCSKS-HTNKEAIRKAGGIPLLARLLKTSHENMLIPVV- 653 + +V+ CGAL KS NK A++ GGIP L RLL+ S + + +V Sbjct: 581 ----HRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVT 636 Query: 654 GTLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKETRDLVRLH 713 G L +S + A+K II + + L N + H +D + + L Sbjct: 637 GVLWNLSSCD----AVKMT-IIRDALSTLT--NTVIVPHSGWNNSSFDDDHKIKFQTSL- 688 Query: 714 GGLKPLASLLNNTDNKERLAAVTGAIWKCSISKENVTKFREYKAIETLVGLL-------- 765 +L NT TG + S + E K + ++ E LV L Sbjct: 689 --------VLRNT---------TGCLRNLSSAGEEARK--QMRSCEGLVDSLLYVIHTCV 729 Query: 766 --TDQPEEVLVNVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGA 823 +D + + N V L E V + G+ L +LL G + G Sbjct: 730 NTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLNELDDLL-GKESPSKDSEPSCWGK 788 Query: 824 CAVEPESMMIIDRLDGVRLLWSLLKNP-------HPDVKASAAWALCPCIKNAK---DAG 873 + + D+ DGV + L K+P HP V L A AG Sbjct: 789 KKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAG 848 Query: 874 EMVRSFVG----------------GLELIVNLLKSDNKEVLASVCAAITNIAKDQENLAV 917 + G GL ++V LL+ DN V++SV A+ N+A D N + Sbjct: 849 SLQNLSAGNWKFAAYIRAAVRKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKEL 908 Query: 918 ITDHGVVPLLSKLANTNNNKLRHHLAEAISRCCMWG------RNRVAFGEHKAVAPLVRY 971 I + + L+++L N + A C + N A + + LV Sbjct: 909 IGKYAMRDLVNRLPGGNGPSVLSDETMAAICCALHEVTSKNMENAKALADSGGIEKLVNI 968 Query: 972 LKS----NDTNVHRATAQALYQLSEDAD 995 K + V +A AQ L L + D Sbjct: 969 TKGRGDRSSLKVVKAAAQVLNTLWQYRD 996 >gi|53829374 plakophilin 4 isoform a [Homo sapiens] Length = 1192 Score = 50.1 bits (118), Expect = 1e-05 Identities = 119/508 (23%), Positives = 188/508 (37%), Gaps = 90/508 (17%) Query: 537 LPIMVNILDSPHKSLKCLAAETIANVA-KFKRARRVVRQHGGITKLVALLDCAHDSTKPA 595 LP ++++L S++ AA + ++ + + V + GGI LV LLD Sbjct: 530 LPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRLGGIKHLVDLLD--------- 580 Query: 596 QSSLYEARDVEVARCGALALWSCSKS-HTNKEAIRKAGGIPLLARLLKTSHENMLIPVV- 653 + +V+ CGAL KS NK A++ GGIP L RLL+ S + + +V Sbjct: 581 ----HRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVT 636 Query: 654 GTLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKETRDLVRLH 713 G L +S + A+K II + + L N + H +D + + L Sbjct: 637 GVLWNLSSCD----AVKMT-IIRDALSTLT--NTVIVPHSGWNNSSFDDDHKIKFQTSL- 688 Query: 714 GGLKPLASLLNNTDNKERLAAVTGAIWKCSISKENVTKFREYKAIETLVGLL-------- 765 +L NT TG + S + E K + ++ E LV L Sbjct: 689 --------VLRNT---------TGCLRNLSSAGEEARK--QMRSCEGLVDSLLYVIHTCV 729 Query: 766 --TDQPEEVLVNVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGA 823 +D + + N V L E V + G+ L +LL G + G Sbjct: 730 NTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLNELDDLL-GKESPSKDSEPSCWGK 788 Query: 824 CAVEPESMMIIDRLDGVRLLWSLLKNP-------HPDVKASAAWALCPCIKNAK---DAG 873 + + D+ DGV + L K+P HP V L A AG Sbjct: 789 KKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAG 848 Query: 874 EMVRSFVG----------------GLELIVNLLKSDNKEVLASVCAAITNIAKDQENLAV 917 + G GL ++V LL+ DN V++SV A+ N+A D N + Sbjct: 849 SLQNLSAGNWKFAAYIRAAVRKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKEL 908 Query: 918 ITDHGVVPLLSKLANTNNNKLRHHLAEAISRCCMWG------RNRVAFGEHKAVAPLVRY 971 I + + L+++L N + A C + N A + + LV Sbjct: 909 IGKYAMRDLVNRLPGGNGPSVLSDETMAAICCALHEVTSKNMENAKALADSGGIEKLVNI 968 Query: 972 LKS----NDTNVHRATAQALYQLSEDAD 995 K + V +A AQ L L + D Sbjct: 969 TKGRGDRSSLKVVKAAAQVLNTLWQYRD 996 >gi|6912678 sperm associated antigen 6 isoform 1 [Homo sapiens] Length = 509 Score = 49.3 bits (116), Expect = 2e-05 Identities = 74/329 (22%), Positives = 131/329 (39%), Gaps = 53/329 (16%) Query: 489 AIRDVGGLEVLINLLETDEVKCKIGSLKILKEIS-HNPQIRQNIVDLGGLPIMVNILDSP 547 AI D G L+ L+ LE + K + L+ I+ HN ++ Q +VD G +P++V + P Sbjct: 120 AIVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEP 179 Query: 548 HKSLKCLAAETIANVAKFK-RARRVVRQHGGITKLVALL--------------------- 585 +LK +AA ++++AK + V G + L ++ Sbjct: 180 EIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKH 239 Query: 586 --DCAHDSTK----PAQSSLYEARDVEVARCGALALWSCSKSHTNK--EAIRKAGGIPLL 637 D A + P + + +D V + + + +K HT + + + AGG+ + Sbjct: 240 SVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAK-HTPELSQLVVNAGGVAAV 298 Query: 638 ARLLKTSHENMLIPVVGTL-QECASEENYRAAIKAERIIENLVKNLNSENE-QLQEHCAM 695 + + N +P + L A EN A+ + + L L+ E E ++ A Sbjct: 299 IDCIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAW 358 Query: 696 AIYQCA-EDKETRDLVRLHGGLKPLASLLNNTDNKERL-----AAVTGAIWKCSISKENV 749 A+ Q E V + L L SL +T++ E L A+ + KC+ Sbjct: 359 ALGQIGRHTPEHARAVAVTNTLPVLLSLYMSTESSEDLQVKSKKAIKNILQKCTY----- 413 Query: 750 TKFREYKAIETLVGLLTDQPEEVLVNVVG 778 + L L D P +L +VVG Sbjct: 414 --------LPALEPFLYDAPPNILKHVVG 434 Score = 38.9 bits (89), Expect = 0.026 Identities = 56/291 (19%), Positives = 117/291 (40%), Gaps = 20/291 (6%) Query: 497 EVLINLLETDEVKCKIGSLKILKEISHNPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAA 556 +++ +L E + K + + H+PQ+ Q IVD G L +V L+ +K AA Sbjct: 87 QLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLEDFDPGVKEAAA 146 Query: 557 ETIANVAKFK-RARRVVRQHGGITKLVALLDCAHDSTKPAQSSLYEARDVEVARCGALAL 615 + +A+ + V G + LV + + ++ + R A AL Sbjct: 147 WALRYIARHNAELSQAVVDAGAVPLLVLCI---------------QEPEIALKRIAASAL 191 Query: 616 WSCSK-SHTNKEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECASEENYRAAIKAE-R 673 +K S + + AG + LA+++ + ++ L + + A + E Sbjct: 192 SDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHSVDLAEMVVEAE 251 Query: 674 IIENLVKNLNSENEQLQEHCAMAIYQCAE-DKETRDLVRLHGGLKPLASLLNNTDNKERL 732 I ++ L ++E ++++ + I + A+ E LV GG+ + + + RL Sbjct: 252 IFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVIDCIGSCKGNTRL 311 Query: 733 AAVTGAIWKCSISKENVTKFREYKAIETLVGLLTDQPEE-VLVNVVGALGE 782 + + + S+ K + L L+++PE+ + ALG+ Sbjct: 312 PGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWALGQ 362 Score = 31.2 bits (69), Expect = 5.3 Identities = 47/216 (21%), Positives = 84/216 (38%), Gaps = 4/216 (1%) Query: 821 VGACAVEPESMMIIDRLDGVRLLWSLLKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFV 880 V A P+++ + + LL +LL + P ++ +AA AL D E V Sbjct: 24 VAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQTAALALGRLANYNDDLAEAVVK-C 82 Query: 881 GGLELIVNLLKSDNKEVLASVCAAITNIAKDQENLA-VITDHGVVPLLSKLANTNNNKLR 939 L +V L N+ + + + K LA I D G + L + ++ Sbjct: 83 DILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLEDFDPGVK 142 Query: 940 HHLAEAISRCCMWGRN-RVAFGEHKAVAPLVRYLKSNDTNVHRATAQALYQLSEDADNCI 998 A A+ A + AV LV ++ + + R A AL +++ + Sbjct: 143 EAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPEIALKRIAASALSDIAKHSPELA 202 Query: 999 -TMHENGAVKLLLDMVGSPDQDLQEAAAGCISNIRR 1033 T+ + GAV L M+ +PD L+ +S + + Sbjct: 203 QTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSK 238 >gi|27262641 sperm associated antigen 6 isoform 2 [Homo sapiens] Length = 458 Score = 49.3 bits (116), Expect = 2e-05 Identities = 74/329 (22%), Positives = 131/329 (39%), Gaps = 53/329 (16%) Query: 489 AIRDVGGLEVLINLLETDEVKCKIGSLKILKEIS-HNPQIRQNIVDLGGLPIMVNILDSP 547 AI D G L+ L+ LE + K + L+ I+ HN ++ Q +VD G +P++V + P Sbjct: 120 AIVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEP 179 Query: 548 HKSLKCLAAETIANVAKFK-RARRVVRQHGGITKLVALL--------------------- 585 +LK +AA ++++AK + V G + L ++ Sbjct: 180 EIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKH 239 Query: 586 --DCAHDSTK----PAQSSLYEARDVEVARCGALALWSCSKSHTNK--EAIRKAGGIPLL 637 D A + P + + +D V + + + +K HT + + + AGG+ + Sbjct: 240 SVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAK-HTPELSQLVVNAGGVAAV 298 Query: 638 ARLLKTSHENMLIPVVGTL-QECASEENYRAAIKAERIIENLVKNLNSENE-QLQEHCAM 695 + + N +P + L A EN A+ + + L L+ E E ++ A Sbjct: 299 IDCIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAW 358 Query: 696 AIYQCA-EDKETRDLVRLHGGLKPLASLLNNTDNKERL-----AAVTGAIWKCSISKENV 749 A+ Q E V + L L SL +T++ E L A+ + KC+ Sbjct: 359 ALGQIGRHTPEHARAVAVTNTLPVLLSLYMSTESSEDLQVKSKKAIKNILQKCTY----- 413 Query: 750 TKFREYKAIETLVGLLTDQPEEVLVNVVG 778 + L L D P +L +VVG Sbjct: 414 --------LPALEPFLYDAPPNILKHVVG 434 Score = 38.9 bits (89), Expect = 0.026 Identities = 56/291 (19%), Positives = 117/291 (40%), Gaps = 20/291 (6%) Query: 497 EVLINLLETDEVKCKIGSLKILKEISHNPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAA 556 +++ +L E + K + + H+PQ+ Q IVD G L +V L+ +K AA Sbjct: 87 QLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLEDFDPGVKEAAA 146 Query: 557 ETIANVAKFK-RARRVVRQHGGITKLVALLDCAHDSTKPAQSSLYEARDVEVARCGALAL 615 + +A+ + V G + LV + + ++ + R A AL Sbjct: 147 WALRYIARHNAELSQAVVDAGAVPLLVLCI---------------QEPEIALKRIAASAL 191 Query: 616 WSCSK-SHTNKEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECASEENYRAAIKAE-R 673 +K S + + AG + LA+++ + ++ L + + A + E Sbjct: 192 SDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHSVDLAEMVVEAE 251 Query: 674 IIENLVKNLNSENEQLQEHCAMAIYQCAE-DKETRDLVRLHGGLKPLASLLNNTDNKERL 732 I ++ L ++E ++++ + I + A+ E LV GG+ + + + RL Sbjct: 252 IFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVIDCIGSCKGNTRL 311 Query: 733 AAVTGAIWKCSISKENVTKFREYKAIETLVGLLTDQPEE-VLVNVVGALGE 782 + + + S+ K + L L+++PE+ + ALG+ Sbjct: 312 PGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWALGQ 362 Score = 31.2 bits (69), Expect = 5.3 Identities = 47/216 (21%), Positives = 84/216 (38%), Gaps = 4/216 (1%) Query: 821 VGACAVEPESMMIIDRLDGVRLLWSLLKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFV 880 V A P+++ + + LL +LL + P ++ +AA AL D E V Sbjct: 24 VAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQTAALALGRLANYNDDLAEAVVK-C 82 Query: 881 GGLELIVNLLKSDNKEVLASVCAAITNIAKDQENLA-VITDHGVVPLLSKLANTNNNKLR 939 L +V L N+ + + + K LA I D G + L + ++ Sbjct: 83 DILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLEDFDPGVK 142 Query: 940 HHLAEAISRCCMWGRN-RVAFGEHKAVAPLVRYLKSNDTNVHRATAQALYQLSEDADNCI 998 A A+ A + AV LV ++ + + R A AL +++ + Sbjct: 143 EAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPEIALKRIAASALSDIAKHSPELA 202 Query: 999 -TMHENGAVKLLLDMVGSPDQDLQEAAAGCISNIRR 1033 T+ + GAV L M+ +PD L+ +S + + Sbjct: 203 QTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSK 238 >gi|39812229 karyopherin alpha 5 [Homo sapiens] Length = 539 Score = 48.9 bits (115), Expect = 2e-05 Identities = 52/191 (27%), Positives = 79/191 (41%), Gaps = 10/191 (5%) Query: 679 VKNLNSENEQLQEHCAMAIYQCAEDK-ETRDLVRLHGGLKPLASLLNNTDNKERLAAVTG 737 +K LNSE+E +QE A+ A D E RD V L PL LL N++ RL Sbjct: 176 IKLLNSEHEDVQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELLTNSN---RLTTTRN 232 Query: 738 AIWKCS---ISKENVTKFREYK-AIETLVGLLTDQPEEVLVNVVGALGECCQERENRV-I 792 A+W S K F + + L LL +VL +V AL +++ Sbjct: 233 AVWALSNLCRGKNPPPNFSKVSPCLNVLSRLLFSSDPDVLADVCWALSYLSDGPNDKIQA 292 Query: 793 VRKCGGIQPLVNLLVGINQALLVNVTKAVGACAVEPE-SMMIIDRLDGVRLLWSLLKNPH 851 V G + LV LL+ + ++ +AVG + +I + L LL +P Sbjct: 293 VIDSGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPK 352 Query: 852 PDVKASAAWAL 862 ++ A W + Sbjct: 353 ESIRKEACWTV 363 Score = 35.4 bits (80), Expect = 0.28 Identities = 23/82 (28%), Positives = 44/82 (53%), Gaps = 1/82 (1%) Query: 489 AIRDVGGLEVLINLLETDEVKCKIGSLKILKEISHNPQIR-QNIVDLGGLPIMVNILDSP 547 A+ D G L+ LL ++ K +L+ + I I+ Q I++ LP ++++L SP Sbjct: 292 AVIDSGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSP 351 Query: 548 HKSLKCLAAETIANVAKFKRAR 569 +S++ A T++N+ RA+ Sbjct: 352 KESIRKEACWTVSNITAGNRAQ 373 Score = 32.7 bits (73), Expect = 1.8 Identities = 44/209 (21%), Positives = 90/209 (43%), Gaps = 17/209 (8%) Query: 833 IIDRLDGVRLLWSLLKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFVGGLELIVNLLK- 891 ++ V + LL + H DV+ A WAL N R FV E++ LL+ Sbjct: 165 VVIETGAVPIFIKLLNSEHEDVQEQAVWAL----GNIAGDNAECRDFVLNCEILPPLLEL 220 Query: 892 ---SDNKEVLASVCAAITNIAKDQE---NLAVITDHGVVPLLSKLANTNNNKLRHHLAEA 945 S+ + A++N+ + + N + ++ + +LS+L +++ + + A Sbjct: 221 LTNSNRLTTTRNAVWALSNLCRGKNPPPNFSKVSP--CLNVLSRLLFSSDPDVLADVCWA 278 Query: 946 ISRCCMWGRNRV-AFGEHKAVAPLVRYLKSNDTNVHRATAQALYQL--SEDADNCITMHE 1002 +S +++ A + LV L ND V +A+ + +D + ++ Sbjct: 279 LSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILN- 337 Query: 1003 NGAVKLLLDMVGSPDQDLQEAAAGCISNI 1031 A+ LL ++ SP + +++ A +SNI Sbjct: 338 CSALPCLLHLLSSPKESIRKEACWTVSNI 366 >gi|28875784 armadillo repeat containing 5 isoform b [Homo sapiens] Length = 725 Score = 47.8 bits (112), Expect = 6e-05 Identities = 65/252 (25%), Positives = 109/252 (43%), Gaps = 21/252 (8%) Query: 780 LGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVT-KAVGACAVEPESMMIIDRLD 838 L +CC E R VR+ GGI PLV +L + + N T +A+G A+EPES I Sbjct: 136 LADCCTEGACRTEVRRLGGILPLVTILQCMKTDSIQNRTARALGNLAMEPESCGDIHCAG 195 Query: 839 GVRLLWSLLKNPHPDVKASAAWALCPCIKNAKDAGE--MVRSFVGGLELIVNLLKSDNKE 896 V LL L + ++ ++N D+ + + + G + + LL + Sbjct: 196 AVPLLVESLTACQ---DSQCLQSVVRALRNLADSPQHRLALAQQGAVRPLAELLATAPDA 252 Query: 897 VLA-SVCAAITNIAKD-----QENLAVITDHGVVPLLSKLANTNNNKLRHHLAEAISRCC 950 L ++ A+ +++ E L++ G+ PL+S LA+ +R ++ C Sbjct: 253 ALTLALVRALLELSRGCSRACAEQLSL--GGGLGPLVS-LASHPKRAVREGTILILANLC 309 Query: 951 MWGRNRVAFGEHKAVAPLVRYLKS-NDTNVHRATAQ-----ALYQLSEDADNCITMHENG 1004 G R A G V LV L+ D N T+Q A+ L +A N + + G Sbjct: 310 AQGLIRPALGNAGGVEVLVDELRQRRDPNGASPTSQQPLVRAVCLLCREAINRARLRDAG 369 Query: 1005 AVKLLLDMVGSP 1016 + LL+ ++ P Sbjct: 370 GLDLLMGLLRDP 381 Score = 42.4 bits (98), Expect = 0.002 Identities = 68/276 (24%), Positives = 101/276 (36%), Gaps = 51/276 (18%) Query: 554 LAAETIANVAKFKRARRVVRQHGGITKLVALLDCAH-DSTKPAQSSLYEARDVEVARCGA 612 LA +A+ R VR+ GGI LV +L C DS + + +E CG Sbjct: 131 LALSILADCCTEGACRTEVRRLGGILPLVTILQCMKTDSIQNRTARALGNLAMEPESCG- 189 Query: 613 LALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENM-LIPVVGTLQECASEENYRAAIKA 671 I AG +PLL L ++ L VV L+ A +R A+ Sbjct: 190 --------------DIHCAGAVPLLVESLTACQDSQCLQSVVRALRNLADSPQHRLALAQ 235 Query: 672 ERIIENLVKNLNSENE------------QLQEHCAMAIYQCAEDKETRDLVRLHGGLKPL 719 + + L + L + + +L C+ A CAE + L GGL PL Sbjct: 236 QGAVRPLAELLATAPDAALTLALVRALLELSRGCSRA---CAEQ------LSLGGGLGPL 286 Query: 720 ASLLNNTDNKERLAAVTGAIWKCSISKENVTKFREYKAIETLVGLLTDQ---------PE 770 SL ++ R + C+ +E LV L + + Sbjct: 287 VSLASHPKRAVREGTILILANLCAQGLIR-PALGNAGGVEVLVDELRQRRDPNGASPTSQ 345 Query: 771 EVLVNVVGALGECCQERENRVIVRKCGGIQPLVNLL 806 + LV V L C+E NR +R GG+ L+ LL Sbjct: 346 QPLVRAVCLL---CREAINRARLRDAGGLDLLMGLL 378 Score = 38.1 bits (87), Expect = 0.044 Identities = 29/103 (28%), Positives = 49/103 (47%), Gaps = 7/103 (6%) Query: 946 ISRCCMWGRNRVAFGEHKAVAPLVRYLKSNDTN-VHRATAQALYQLSEDADNCITMHENG 1004 ++ CC G R + PLV L+ T+ + TA+AL L+ + ++C +H G Sbjct: 136 LADCCTEGACRTEVRRLGGILPLVTILQCMKTDSIQNRTARALGNLAMEPESCGDIHCAG 195 Query: 1005 AVKLLLD-MVGSPDQDLQEAAAGCISNI-----RRLALATEKA 1041 AV LL++ + D ++ + N+ RLALA + A Sbjct: 196 AVPLLVESLTACQDSQCLQSVVRALRNLADSPQHRLALAQQGA 238 Score = 35.8 bits (81), Expect = 0.22 Identities = 35/157 (22%), Positives = 70/157 (44%), Gaps = 5/157 (3%) Query: 880 VGGLELIVNLLKSDNKEVLASVCA-AITNIAKDQENLAVITDHGVVPLL-SKLANTNNNK 937 +GG+ +V +L+ + + + A A+ N+A + E+ I G VPLL L +++ Sbjct: 152 LGGILPLVTILQCMKTDSIQNRTARALGNLAMEPESCGDIHCAGAVPLLVESLTACQDSQ 211 Query: 938 LRHHLAEAISRCCMWGRNRVAFGEHKAVAPLVRYL-KSNDTNVHRATAQALYQLSEDADN 996 + A+ ++R+A + AV PL L + D + A +AL +LS Sbjct: 212 CLQSVVRALRNLADSPQHRLALAQQGAVRPLAELLATAPDAALTLALVRALLELSRGCSR 271 Query: 997 CIT--MHENGAVKLLLDMVGSPDQDLQEAAAGCISNI 1031 + G + L+ + P + ++E ++N+ Sbjct: 272 ACAEQLSLGGGLGPLVSLASHPKRAVREGTILILANL 308 Score = 30.8 bits (68), Expect = 7.0 Identities = 44/213 (20%), Positives = 82/213 (38%), Gaps = 17/213 (7%) Query: 487 QLAIRDVGGLEVLINLLET-DEVKCKIGSLKILKEISH--NPQIRQNIVDLGGLPIMVNI 543 +LA+ G + L LL T + + ++ L E+S + + + GGL +V++ Sbjct: 230 RLALAQQGAVRPLAELLATAPDAALTLALVRALLELSRGCSRACAEQLSLGGGLGPLVSL 289 Query: 544 LDSPHKSLKCLAAETIANVAKFKRARRVVRQHGGITKLVALLDCAHDSTKPAQSSLYEAR 603 P ++++ +AN+ R + GG+ LV L D + +S Sbjct: 290 ASHPKRAVREGTILILANLCAQGLIRPALGNAGGVEVLVDELRQRRDPNGASPTSQQPLV 349 Query: 604 DVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTS-----HENMLIPVVGTLQE 658 C + N+ +R AGG+ LL LL+ H ++ +VG L + Sbjct: 350 RAVCLLC---------REAINRARLRDAGGLDLLMGLLRDPRASAWHPRIVAALVGFLYD 400 Query: 659 CASEENYRAAIKAERIIENLVKNLNSENEQLQE 691 + +A + L E E+ +E Sbjct: 401 TGALGRLQALGLVPLLAGQLCGEAGEEEEEGRE 433 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.132 0.379 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 37,782,460 Number of Sequences: 37866 Number of extensions: 1642765 Number of successful extensions: 7320 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 52 Number of HSP's successfully gapped in prelim test: 134 Number of HSP's that attempted gapping in prelim test: 6559 Number of HSP's gapped (non-prelim): 717 length of query: 1044 length of database: 18,247,518 effective HSP length: 112 effective length of query: 932 effective length of database: 14,006,526 effective search space: 13054082232 effective search space used: 13054082232 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.