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Search of human proteins with 31543670
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31543670 synaptotagmin II [Homo sapiens]
(419 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|211059429 synaptotagmin II [Homo sapiens] 854 0.0
gi|31543670 synaptotagmin II [Homo sapiens] 854 0.0
gi|209447073 synaptotagmin I [Homo sapiens] 649 0.0
gi|5032139 synaptotagmin I [Homo sapiens] 649 0.0
gi|209447070 synaptotagmin I [Homo sapiens] 649 0.0
gi|92859638 synaptotagmin V [Homo sapiens] 481 e-136
gi|45504376 synaptotagmin VI [Homo sapiens] 295 4e-80
gi|94536846 synaptotagmin VIII [Homo sapiens] 295 7e-80
gi|38570146 synaptotagmin VII [Homo sapiens] 294 1e-79
gi|39752671 synaptotagmin X [Homo sapiens] 285 5e-77
gi|238550198 synaptotagmin III [Homo sapiens] 283 3e-76
gi|238550196 synaptotagmin III [Homo sapiens] 283 3e-76
gi|14150054 synaptotagmin III [Homo sapiens] 283 3e-76
gi|28376627 synaptotagmin IX [Homo sapiens] 281 8e-76
gi|216548478 synaptotagmin XI [Homo sapiens] 231 9e-61
gi|24308219 synaptotagmin IV [Homo sapiens] 227 1e-59
gi|40068038 B/K protein [Homo sapiens] 222 4e-58
gi|6005997 double C2-like domains, beta [Homo sapiens] 186 3e-47
gi|31881675 synaptotagmin XV isoform a [Homo sapiens] 174 1e-43
gi|47078261 double C2-like domains, alpha [Homo sapiens] 170 2e-42
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens] 169 6e-42
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens] 169 6e-42
gi|29366828 synaptotagmin XII [Homo sapiens] 167 2e-41
gi|193804862 synaptotagmin-like 4 [Homo sapiens] 146 4e-35
gi|193804860 synaptotagmin-like 4 [Homo sapiens] 146 4e-35
gi|24308233 synaptotagmin XIII [Homo sapiens] 144 1e-34
gi|31881667 synaptotagmin XV isoform b [Homo sapiens] 144 2e-34
gi|239744413 PREDICTED: hypothetical protein LOC390213 [Homo sap... 126 3e-29
gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens] 124 2e-28
gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens] 124 2e-28
>gi|211059429 synaptotagmin II [Homo sapiens]
Length = 419
Score = 854 bits (2207), Expect = 0.0
Identities = 419/419 (100%), Positives = 419/419 (100%)
Query: 1 MRNIFKRNQEPIVAPATTTATMPIGPVDNSTESGGAGESQEDMFAKLKEKLFNEINKIPL 60
MRNIFKRNQEPIVAPATTTATMPIGPVDNSTESGGAGESQEDMFAKLKEKLFNEINKIPL
Sbjct: 1 MRNIFKRNQEPIVAPATTTATMPIGPVDNSTESGGAGESQEDMFAKLKEKLFNEINKIPL 60
Query: 61 PPWALIAIAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGKGMKNAMNMKDMKGGQDDDDA 120
PPWALIAIAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGKGMKNAMNMKDMKGGQDDDDA
Sbjct: 61 PPWALIAIAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGKGMKNAMNMKDMKGGQDDDDA 120
Query: 121 ETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVK 180
ETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVK
Sbjct: 121 ETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVK 180
Query: 181 VFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGE 240
VFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGE
Sbjct: 181 VFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGE 240
Query: 241 VKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKM 300
VKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKM
Sbjct: 241 VKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKM 300
Query: 301 DVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVL 360
DVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVL
Sbjct: 301 DVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVL 360
Query: 361 DYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALLGKNK 419
DYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALLGKNK
Sbjct: 361 DYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALLGKNK 419
>gi|31543670 synaptotagmin II [Homo sapiens]
Length = 419
Score = 854 bits (2207), Expect = 0.0
Identities = 419/419 (100%), Positives = 419/419 (100%)
Query: 1 MRNIFKRNQEPIVAPATTTATMPIGPVDNSTESGGAGESQEDMFAKLKEKLFNEINKIPL 60
MRNIFKRNQEPIVAPATTTATMPIGPVDNSTESGGAGESQEDMFAKLKEKLFNEINKIPL
Sbjct: 1 MRNIFKRNQEPIVAPATTTATMPIGPVDNSTESGGAGESQEDMFAKLKEKLFNEINKIPL 60
Query: 61 PPWALIAIAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGKGMKNAMNMKDMKGGQDDDDA 120
PPWALIAIAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGKGMKNAMNMKDMKGGQDDDDA
Sbjct: 61 PPWALIAIAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGKGMKNAMNMKDMKGGQDDDDA 120
Query: 121 ETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVK 180
ETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVK
Sbjct: 121 ETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVK 180
Query: 181 VFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGE 240
VFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGE
Sbjct: 181 VFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGE 240
Query: 241 VKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKM 300
VKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKM
Sbjct: 241 VKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKM 300
Query: 301 DVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVL 360
DVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVL
Sbjct: 301 DVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVL 360
Query: 361 DYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALLGKNK 419
DYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALLGKNK
Sbjct: 361 DYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALLGKNK 419
>gi|209447073 synaptotagmin I [Homo sapiens]
Length = 422
Score = 649 bits (1674), Expect = 0.0
Identities = 324/424 (76%), Positives = 354/424 (83%), Gaps = 11/424 (2%)
Query: 4 IFKRNQEPIVAPATTTATMPIGPVDNSTESGGAGESQEDMFAKLKEKLFNEINKIPLPPW 63
+ + + E + AP TT + N+TE GE +ED F+KLKEK NE++KIPLPPW
Sbjct: 2 VSESHHEALAAPPVTTVATVLP--SNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPW 59
Query: 64 ALIAIAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGKGMKNAMNMKDMKG--------GQ 115
ALIAIA+VA LL+LTCCFCICKKC KKK KK K KG KNA+NMKD+K
Sbjct: 60 ALIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQAL 119
Query: 116 DDDDAETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTS 175
DDDAETGLT+GE E EE KE E LGKLQ+SLDYDFQ NQL VG++QAAELPALDMGGTS
Sbjct: 120 KDDDAETGLTDGE-EKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTS 178
Query: 176 DPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKH 235
DPYVKVFLLPDKKKK+ETKVHRKTLNP FNE FTFKVPY ELGGKTLVMA+YDFDRFSKH
Sbjct: 179 DPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKH 238
Query: 236 DIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAK 295
DIIGE KVPMNTVD G EEWRDLQ EKEE EKLGDIC SLRYVPTAGKLTV ILEAK
Sbjct: 239 DIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAK 298
Query: 296 NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQV 355
NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTT+KK TLNPY+NESFSFE+PFEQIQKVQV
Sbjct: 299 NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQV 358
Query: 356 VVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALL 415
VVTVLDYDK+GKN+AIGK+FVG N+TG ELRHWSDMLANPRRPIAQWH+L+ EEEVDA+L
Sbjct: 359 VVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAML 418
Query: 416 GKNK 419
K
Sbjct: 419 AVKK 422
>gi|5032139 synaptotagmin I [Homo sapiens]
Length = 422
Score = 649 bits (1674), Expect = 0.0
Identities = 324/424 (76%), Positives = 354/424 (83%), Gaps = 11/424 (2%)
Query: 4 IFKRNQEPIVAPATTTATMPIGPVDNSTESGGAGESQEDMFAKLKEKLFNEINKIPLPPW 63
+ + + E + AP TT + N+TE GE +ED F+KLKEK NE++KIPLPPW
Sbjct: 2 VSESHHEALAAPPVTTVATVLP--SNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPW 59
Query: 64 ALIAIAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGKGMKNAMNMKDMKG--------GQ 115
ALIAIA+VA LL+LTCCFCICKKC KKK KK K KG KNA+NMKD+K
Sbjct: 60 ALIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQAL 119
Query: 116 DDDDAETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTS 175
DDDAETGLT+GE E EE KE E LGKLQ+SLDYDFQ NQL VG++QAAELPALDMGGTS
Sbjct: 120 KDDDAETGLTDGE-EKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTS 178
Query: 176 DPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKH 235
DPYVKVFLLPDKKKK+ETKVHRKTLNP FNE FTFKVPY ELGGKTLVMA+YDFDRFSKH
Sbjct: 179 DPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKH 238
Query: 236 DIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAK 295
DIIGE KVPMNTVD G EEWRDLQ EKEE EKLGDIC SLRYVPTAGKLTV ILEAK
Sbjct: 239 DIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAK 298
Query: 296 NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQV 355
NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTT+KK TLNPY+NESFSFE+PFEQIQKVQV
Sbjct: 299 NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQV 358
Query: 356 VVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALL 415
VVTVLDYDK+GKN+AIGK+FVG N+TG ELRHWSDMLANPRRPIAQWH+L+ EEEVDA+L
Sbjct: 359 VVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAML 418
Query: 416 GKNK 419
K
Sbjct: 419 AVKK 422
>gi|209447070 synaptotagmin I [Homo sapiens]
Length = 422
Score = 649 bits (1674), Expect = 0.0
Identities = 324/424 (76%), Positives = 354/424 (83%), Gaps = 11/424 (2%)
Query: 4 IFKRNQEPIVAPATTTATMPIGPVDNSTESGGAGESQEDMFAKLKEKLFNEINKIPLPPW 63
+ + + E + AP TT + N+TE GE +ED F+KLKEK NE++KIPLPPW
Sbjct: 2 VSESHHEALAAPPVTTVATVLP--SNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPW 59
Query: 64 ALIAIAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGKGMKNAMNMKDMKG--------GQ 115
ALIAIA+VA LL+LTCCFCICKKC KKK KK K KG KNA+NMKD+K
Sbjct: 60 ALIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQAL 119
Query: 116 DDDDAETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTS 175
DDDAETGLT+GE E EE KE E LGKLQ+SLDYDFQ NQL VG++QAAELPALDMGGTS
Sbjct: 120 KDDDAETGLTDGE-EKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTS 178
Query: 176 DPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKH 235
DPYVKVFLLPDKKKK+ETKVHRKTLNP FNE FTFKVPY ELGGKTLVMA+YDFDRFSKH
Sbjct: 179 DPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKH 238
Query: 236 DIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAK 295
DIIGE KVPMNTVD G EEWRDLQ EKEE EKLGDIC SLRYVPTAGKLTV ILEAK
Sbjct: 239 DIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAK 298
Query: 296 NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQV 355
NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTT+KK TLNPY+NESFSFE+PFEQIQKVQV
Sbjct: 299 NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQV 358
Query: 356 VVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALL 415
VVTVLDYDK+GKN+AIGK+FVG N+TG ELRHWSDMLANPRRPIAQWH+L+ EEEVDA+L
Sbjct: 359 VVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAML 418
Query: 416 GKNK 419
K
Sbjct: 419 AVKK 422
>gi|92859638 synaptotagmin V [Homo sapiens]
Length = 386
Score = 481 bits (1237), Expect = e-136
Identities = 228/366 (62%), Positives = 293/366 (80%), Gaps = 6/366 (1%)
Query: 53 NEINKIPLPPWALIAIAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGKGMKNAMNMKDMK 112
+ I+ P+PPWAL I +V+GLL+ +CCFC+ +K C +++ KK + + + +K +
Sbjct: 20 SRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSC-RRRTGKKSQAQAQVHLQEVKGL- 77
Query: 113 GGQDDDDAETGLTEGE----GEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPA 168
G D + + E E G G++ + LG+LQ+SLDYDFQ+ QL VG+LQA L A
Sbjct: 78 GQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAA 137
Query: 169 LDMGGTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYD 228
LD+GG+SDPYV+V+LLPDK+++YETKVHR+TLNP F ETF FKVPY ELGG+ LVMA+YD
Sbjct: 138 LDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAVYD 197
Query: 229 FDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLT 288
FDRFS++D IGEV+VPM++VDLG+P++ WR+LQ +EE EKLGDIC SLRYVPTAGKLT
Sbjct: 198 FDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKLGDICFSLRYVPTAGKLT 257
Query: 289 VCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFE 348
V +LEAKNLKKMDVGGLSDPYVK+HL+Q GK+++KKKTT+KK TLNPY+NE+FSFE+P +
Sbjct: 258 VIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCD 317
Query: 349 QIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPE 408
Q+QKVQV +TVLDYDKLGKNEAIG++ VG+ A G LRHW+DMLANPRRPIAQWHSL+P
Sbjct: 318 QVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADMLANPRRPIAQWHSLRPP 377
Query: 409 EEVDAL 414
+ V L
Sbjct: 378 DRVRLL 383
>gi|45504376 synaptotagmin VI [Homo sapiens]
Length = 425
Score = 295 bits (756), Expect = 4e-80
Identities = 141/280 (50%), Positives = 201/280 (71%), Gaps = 3/280 (1%)
Query: 128 EGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDK 187
+GE + + ++ GK+ FSL YD++ L V +L+A +LPA D G+SDPYVK++LLPD+
Sbjct: 133 DGEDAKSEATKSCGKINFSLRYDYETETLIVRILKAFDLPAKDFCGSSDPYVKIYLLPDR 192
Query: 188 KKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVP--M 245
K K +T+VHRKTLNP F+E F F VPY+EL + L ++++DFDRFS+HD+IGEV +
Sbjct: 193 KCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRFSRHDMIGEVILDNLF 252
Query: 246 NTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGL 305
DL + W+D+Q E + LG+I SL Y+PTAG+LT+ +++ +NLK MD+ G
Sbjct: 253 EASDLSRETSIWKDIQYATSESVD-LGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGY 311
Query: 306 SDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKL 365
SDPYVK+ L+ +G+RLKKKKTT+KK TLNP +NE+ F+IP E + +V ++++V+DYD++
Sbjct: 312 SDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVSLLISVMDYDRV 371
Query: 366 GKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSL 405
G NE IG VG A G HW++MLA PR+PIA WHSL
Sbjct: 372 GHNEIIGVCRVGITAEGLGRDHWNEMLAYPRKPIAHWHSL 411
>gi|94536846 synaptotagmin VIII [Homo sapiens]
Length = 401
Score = 295 bits (754), Expect = 7e-80
Identities = 157/360 (43%), Positives = 229/360 (63%), Gaps = 21/360 (5%)
Query: 59 PLPPWALIAIAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGK---GMKNAMNMKDMKGGQ 115
P P WALIA A+ AG+LL++C +C CCC ++ KK + K G+ +A Q
Sbjct: 45 PWPRWALIAGALAAGVLLVSCL--LCAACCCCRRHRKKPRDKESVGLGSARGTTTTHLVQ 102
Query: 116 DDDDAETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTS 175
D D GL G+ ++ G+LQ SL++DF + ++ VG+ QAA+L GGT
Sbjct: 103 PDVD---GLESSPGDAQQ------WGRLQLSLEFDFGSQEIRVGLRQAADLRP---GGTV 150
Query: 176 DPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKH 235
DPY +V + ++ETKVHR TL P F+ET F +P EL G TL + +++F RFS H
Sbjct: 151 DPYARVSVSTQAGHRHETKVHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGH 210
Query: 236 DIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAK 295
+ +GE+++P+ TVDL +E W L +PE++G++C SLRYVP++G+LTV +LEA+
Sbjct: 211 EPLGELRLPLGTVDLQHVLEHWYLLGPPAATQPEQVGELCFSLRYVPSSGRLTVVVLEAR 270
Query: 296 NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQV 355
L+ GL++PYVK+ LM N ++ KK+KT KK T PYFNE+F+F +PF Q+Q V +
Sbjct: 271 GLRP----GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDL 326
Query: 356 VVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALL 415
V+ V D + E +GK+ +G+ A+G L+HW+DMLA+ RRPIAQ H L+P EVD +L
Sbjct: 327 VLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARRPIAQRHPLRPAREVDRML 386
>gi|38570146 synaptotagmin VII [Homo sapiens]
Length = 403
Score = 294 bits (752), Expect = 1e-79
Identities = 141/280 (50%), Positives = 200/280 (71%), Gaps = 2/280 (0%)
Query: 128 EGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDK 187
E E E ENLG++QFS+ Y+FQ + LTV +++A ELPA D GTSDP+VK++LLPDK
Sbjct: 124 EDEAHEGCSRENLGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLLPDK 183
Query: 188 KKKYETKVHRKTLNPAFNETFTFK-VPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMN 246
K K ETKV RK LNP +NETF F+ PY+++ + L + + D+DRFS++D IGEV +P+N
Sbjct: 184 KHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIPLN 243
Query: 247 TVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLS 306
VDL Q W+DL+ + G++ SL Y P+A + V I++A+NLK MD+GG S
Sbjct: 244 KVDLTQMQTFWKDLKPCSDGSGSR-GELLLSLCYNPSANSIIVNIIKARNLKAMDIGGTS 302
Query: 307 DPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLG 366
DPYVK+ LM KR++KKKT K+ LNP FNESF+F+IP E++++ +++TV+D DKL
Sbjct: 303 DPYVKVWLMYKDKRVEKKKTVTMKRNLNPIFNESFAFDIPTEKLRETTIIITVMDKDKLS 362
Query: 367 KNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLK 406
+N+ IGKI++ + E++HW DM+A PR+P+AQWH LK
Sbjct: 363 RNDVIGKIYLSWKSGPGEVKHWKDMIARPRQPVAQWHQLK 402
>gi|39752671 synaptotagmin X [Homo sapiens]
Length = 523
Score = 285 bits (729), Expect = 5e-77
Identities = 136/280 (48%), Positives = 193/280 (68%), Gaps = 3/280 (1%)
Query: 128 EGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDK 187
+ EG + ++ + GKL F+L YD++ L V +++A +LPA D GTSDPYVK++LLPD+
Sbjct: 220 DSEGNQNEDVKICGKLNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDR 279
Query: 188 KKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVP--M 245
KKK++T+VHRKTLNP F+ETF F V Y +L + L ++YDFDRFS+HD+IGEV +
Sbjct: 280 KKKFQTRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILDNLF 339
Query: 246 NTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGL 305
DL + W+D+ E + LG+I SL Y+PTAG++T+ +++ +NLK MD+ G
Sbjct: 340 EVSDLSREATVWKDIHCATTESID-LGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGS 398
Query: 306 SDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKL 365
SDPYVK+ LM G+RLKK+KTT KK TLNP +NE+ F+IP E + +V + + V+DYD++
Sbjct: 399 SDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYDRV 458
Query: 366 GKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSL 405
G NE IG G +A G HW++MLA R+PI WH L
Sbjct: 459 GHNEVIGVCRTGLDAEGLGRDHWNEMLAYHRKPITHWHPL 498
>gi|238550198 synaptotagmin III [Homo sapiens]
Length = 590
Score = 283 bits (723), Expect = 3e-76
Identities = 148/297 (49%), Positives = 203/297 (68%), Gaps = 7/297 (2%)
Query: 127 GEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPD 186
G G GE G++ F+L Y + ++QL V +LQA +LPA D G SDPYVK++LLPD
Sbjct: 288 GPGSGEAGTGAP-CGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPD 346
Query: 187 KKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMN 246
+KKK++TKVHRKTLNP FNETF F VP EL + L ++YDFDRFS+HD+IG+V V N
Sbjct: 347 RKKKFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQV-VLDN 405
Query: 247 TVDLG-QPIEE--WRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVG 303
++L QP + WRD+ G E+ + LG++ SL Y+PTAG+LTV I++A NLK MD+
Sbjct: 406 LLELAEQPPDRPLWRDIVEGGSEKAD-LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLT 464
Query: 304 GLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYD 363
G SDPYVK L+ G+RLKK+KT++KK TLNP +NE+ F++ E ++ V + + V+DYD
Sbjct: 465 GFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYD 524
Query: 364 KLGKNEAIGKIFVGSNATGTELR-HWSDMLANPRRPIAQWHSLKPEEEVDALLGKNK 419
+G NE IG VG +A R HW++MLANPR+P+ WH L E+ V + +K
Sbjct: 525 CIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLVEEKTVTSFTKGSK 581
>gi|238550196 synaptotagmin III [Homo sapiens]
Length = 590
Score = 283 bits (723), Expect = 3e-76
Identities = 148/297 (49%), Positives = 203/297 (68%), Gaps = 7/297 (2%)
Query: 127 GEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPD 186
G G GE G++ F+L Y + ++QL V +LQA +LPA D G SDPYVK++LLPD
Sbjct: 288 GPGSGEAGTGAP-CGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPD 346
Query: 187 KKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMN 246
+KKK++TKVHRKTLNP FNETF F VP EL + L ++YDFDRFS+HD+IG+V V N
Sbjct: 347 RKKKFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQV-VLDN 405
Query: 247 TVDLG-QPIEE--WRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVG 303
++L QP + WRD+ G E+ + LG++ SL Y+PTAG+LTV I++A NLK MD+
Sbjct: 406 LLELAEQPPDRPLWRDIVEGGSEKAD-LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLT 464
Query: 304 GLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYD 363
G SDPYVK L+ G+RLKK+KT++KK TLNP +NE+ F++ E ++ V + + V+DYD
Sbjct: 465 GFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYD 524
Query: 364 KLGKNEAIGKIFVGSNATGTELR-HWSDMLANPRRPIAQWHSLKPEEEVDALLGKNK 419
+G NE IG VG +A R HW++MLANPR+P+ WH L E+ V + +K
Sbjct: 525 CIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLVEEKTVTSFTKGSK 581
>gi|14150054 synaptotagmin III [Homo sapiens]
Length = 590
Score = 283 bits (723), Expect = 3e-76
Identities = 148/297 (49%), Positives = 203/297 (68%), Gaps = 7/297 (2%)
Query: 127 GEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPD 186
G G GE G++ F+L Y + ++QL V +LQA +LPA D G SDPYVK++LLPD
Sbjct: 288 GPGSGEAGTGAP-CGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPD 346
Query: 187 KKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMN 246
+KKK++TKVHRKTLNP FNETF F VP EL + L ++YDFDRFS+HD+IG+V V N
Sbjct: 347 RKKKFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQV-VLDN 405
Query: 247 TVDLG-QPIEE--WRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVG 303
++L QP + WRD+ G E+ + LG++ SL Y+PTAG+LTV I++A NLK MD+
Sbjct: 406 LLELAEQPPDRPLWRDIVEGGSEKAD-LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLT 464
Query: 304 GLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYD 363
G SDPYVK L+ G+RLKK+KT++KK TLNP +NE+ F++ E ++ V + + V+DYD
Sbjct: 465 GFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYD 524
Query: 364 KLGKNEAIGKIFVGSNATGTELR-HWSDMLANPRRPIAQWHSLKPEEEVDALLGKNK 419
+G NE IG VG +A R HW++MLANPR+P+ WH L E+ V + +K
Sbjct: 525 CIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLVEEKTVTSFTKGSK 581
>gi|28376627 synaptotagmin IX [Homo sapiens]
Length = 491
Score = 281 bits (719), Expect = 8e-76
Identities = 135/267 (50%), Positives = 188/267 (70%), Gaps = 3/267 (1%)
Query: 141 GKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKTL 200
GKL F L YD QL V + +A LPA D GTSDPYVK++LLPD+K K++TKVHRKTL
Sbjct: 222 GKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTL 281
Query: 201 NPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVP--MNTVDLGQPIEEWR 258
NP F+E F F VPY +L + L ++YDFDRFS+HD+IG+V V ++ D + W+
Sbjct: 282 NPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWK 341
Query: 259 DLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNG 318
D++ + + LG++ SL Y+PTAG+LT+ I++A+NLK MD+ G SDPYVK+ LM +G
Sbjct: 342 DIEYVTNDNVD-LGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDG 400
Query: 319 KRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGS 378
+RLKK+KT+ K+ TLNP +NE+ F++P E I ++ + + V+DYD++G NE IG VG+
Sbjct: 401 RRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGN 460
Query: 379 NATGTELRHWSDMLANPRRPIAQWHSL 405
A HWS+ML+ PR+PIA WHSL
Sbjct: 461 EAERLGRDHWSEMLSYPRKPIAHWHSL 487
Score = 87.4 bits (215), Expect = 2e-17
Identities = 49/124 (39%), Positives = 74/124 (59%), Gaps = 4/124 (3%)
Query: 139 NLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPD--KKKKYETKVH 196
+LG+L FSL Y A +LT+ +++A L A+D+ G SDPYVKV L+ D + KK +T
Sbjct: 352 DLGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTK 411
Query: 197 RKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEE 256
R TLNP +NE F VP + + L +A+ D+DR ++IIG +V LG+ +
Sbjct: 412 RNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGR--DH 469
Query: 257 WRDL 260
W ++
Sbjct: 470 WSEM 473
Score = 75.5 bits (184), Expect = 8e-14
Identities = 46/141 (32%), Positives = 74/141 (52%), Gaps = 11/141 (7%)
Query: 259 DLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNG 318
D G + + G + L+Y +L V I +A NL D G SDPYVKI+L+ +
Sbjct: 209 DNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPD- 267
Query: 319 KRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGS 378
R K +T V +KTLNP F+E F F +P+ ++ ++ +V D+D+ +++ IG++ V
Sbjct: 268 -RKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVD- 325
Query: 379 NATGTELRHWSDMLANPRRPI 399
H+ D+ PR I
Sbjct: 326 --------HFLDLADFPRECI 338
>gi|216548478 synaptotagmin XI [Homo sapiens]
Length = 431
Score = 231 bits (589), Expect = 9e-61
Identities = 125/303 (41%), Positives = 190/303 (62%), Gaps = 8/303 (2%)
Query: 111 MKGGQDDDDAETGLTEGEGEGEEEKEPEN---LGKLQFSLDYDFQANQLTVGVLQAAELP 167
M G++ T LT GE + PE LG L FS+DY+F L V + +A LP
Sbjct: 126 MDYGEELRSPITSLTPGESKTTSPSSPEEDVMLGSLTFSVDYNFPKKALVVTIQEAHGLP 185
Query: 168 ALD-MGGTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFK-VPYQELGGKTLVMA 225
+D SDPY+K+ +LPDK+ + +T+V RKTL+P F+ETFTF +PY +L L
Sbjct: 186 VMDDQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFL 245
Query: 226 IYDFDRFSKHDIIGEVKVPMNTVDLGQ-PIEEWRDLQGGEKEEPEKLGDICTSLRYVPTA 284
+ FDRFS+ D+IGEV VP+ VD ++ RD+ ++ G++ SL Y P A
Sbjct: 246 VLSFDRFSRDDVIGEVMVPLAGVDPSTGKVQLTRDIIKRNIQKCISRGELQVSLSYQPVA 305
Query: 285 GKLTVCILEAKNLKKMDVGGLS-DPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSF 343
++TV +L+A++L KMD+ GLS +PYVK+++ KR+ KKKT VKK TLNP FNESF +
Sbjct: 306 QRMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFNESFIY 365
Query: 344 EIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNA-TGTELRHWSDMLANPRRPIAQW 402
+IP + + + + V+D+D+ KNE +G++ +G+++ T + HW ++ +PR+P+A+W
Sbjct: 366 DIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPRKPVAKW 425
Query: 403 HSL 405
HSL
Sbjct: 426 HSL 428
>gi|24308219 synaptotagmin IV [Homo sapiens]
Length = 425
Score = 227 bits (579), Expect = 1e-59
Identities = 127/295 (43%), Positives = 182/295 (61%), Gaps = 4/295 (1%)
Query: 114 GQDDDDAETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALD-MG 172
G+ + + L EEK+ E LG L FSL+Y+F+ V + +A LPA+D
Sbjct: 129 GEKESVSPESLKSSTSLTSEEKQ-EKLGTLFFSLEYNFERKAFVVNIKEARGLPAMDEQS 187
Query: 173 GTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFK-VPYQELGGKTLVMAIYDFDR 231
TSDPY+K+ +LP+KK K +T+V RKTL+PAF+ETFTF +PY ++ L I FDR
Sbjct: 188 MTSDPYIKMTILPEKKHKVKTRVLRKTLDPAFDETFTFYGIPYTQIQELALHFTILSFDR 247
Query: 232 FSKHDIIGEVKVPMNTVDLGQ-PIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVC 290
FS+ DIIGEV +P++ ++L + + R++ + G++ SL Y T LTV
Sbjct: 248 FSRDDIIGEVLIPLSGIELSEGKMLMNREIIKRNVRKSSGRGELLISLCYQSTTNTLTVV 307
Query: 291 ILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQI 350
+L+A++L K DV GLSDPYVK++L KR+ KKKT VKK T N FNE F F+IP E +
Sbjct: 308 VLKARHLPKSDVSGLSDPYVKVNLYHAKKRISKKKTHVKKCTPNAVFNELFVFDIPCEGL 367
Query: 351 QKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSL 405
+ + V VLD ++ +NE IG++ +G+ A GT HW ++ PRR IA+WH L
Sbjct: 368 EDISVEFLVLDSERGSRNEVIGQLVLGAAAEGTGGEHWKEICDYPRRQIAKWHVL 422
>gi|40068038 B/K protein [Homo sapiens]
Length = 474
Score = 222 bits (566), Expect = 4e-58
Identities = 119/289 (41%), Positives = 177/289 (61%), Gaps = 9/289 (3%)
Query: 132 EEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPA-LDMGGT------SDPYVKVFLL 184
EE LG L FS YD N LTV V++A +LP + G+ S+PYVK+ LL
Sbjct: 177 EEILSKYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLL 236
Query: 185 PDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVP 244
PD+K +T V RKT P F E +TF++P+ E +TL++ + DFD+FS+H +IG+V VP
Sbjct: 237 PDQKNSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSVP 296
Query: 245 MNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGG 304
+ VDL + W+ L + E E LG++ SL Y+P+AG+L V ++ AK L + DV
Sbjct: 297 LCEVDLVKGGHWWKALIPSSQNEVE-LGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQ 355
Query: 305 LSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDK 364
SDP+VKI L+ K +K KKT+ + T++P++NESFSF++P E+++ +V TV ++
Sbjct: 356 GSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNM 415
Query: 365 LGKNEAIGKIFVGSNATG-TELRHWSDMLANPRRPIAQWHSLKPEEEVD 412
N+ IG+I +G ++G +E HW ML R + QWHSL+ E D
Sbjct: 416 KSSNDFIGRIVIGQYSSGPSETNHWRRMLNTHRTAVEQWHSLRSRAECD 464
>gi|6005997 double C2-like domains, beta [Homo sapiens]
Length = 412
Score = 186 bits (473), Expect = 3e-47
Identities = 113/292 (38%), Positives = 159/292 (54%), Gaps = 9/292 (3%)
Query: 126 EGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLP 185
E + +G E + LG L FSL YD + N L + +A L +D G +DPYVK+ LLP
Sbjct: 113 EPDADGYESDDCTALGTLDFSLLYDQENNALHCTITKAKGLKPMDHNGLADPYVKLHLLP 172
Query: 186 --DKKKKYETKVHRKTLNPAFNETFTFK-VPYQELGGKTLVMAIYDFDRFSKHDIIGEVK 242
K K TK R TLNP +NET T+ + +++ KTL +++ D D+F ++ IGE +
Sbjct: 173 GASKANKLRTKTLRNTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGETR 232
Query: 243 VPM------NTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKN 296
VP+ +T +E+ + E + E+ G I SL+Y L V I+ +
Sbjct: 233 VPLKKLKPNHTKTFNICLEKQLPVDKTEDKSLEERGRILISLKYSSQKQGLLVGIVRCAH 292
Query: 297 LKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVV 356
L MD G SDPYVK +L + + K KT VKKKTLNP FNE F +EI + K +
Sbjct: 293 LAAMDANGYSDPYVKTYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYEIKHGDLAKKSLE 352
Query: 357 VTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPE 408
VTV DYD N+ IG + +G +A G L+HW D L N + I +WH+L E
Sbjct: 353 VTVWDYDIGKSNDFIGGVVLGIHAKGERLKHWFDCLKNKDKRIERWHTLTSE 404
Score = 76.3 bits (186), Expect = 5e-14
Identities = 45/123 (36%), Positives = 67/123 (54%), Gaps = 1/123 (0%)
Query: 252 QPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVK 311
+P E+ D G E ++ LG + SL Y L I +AK LK MD GL+DPYVK
Sbjct: 108 KPPEDEPDADGYESDDCTALGTLDFSLLYDQENNALHCTITKAKGLKPMDHNGLADPYVK 167
Query: 312 IHLMQNGKRLKKKKTTVKKKTLNPYFNESFS-FEIPFEQIQKVQVVVTVLDYDKLGKNEA 370
+HL+ + K +T + TLNP +NE+ + + I E + + + ++V D DK NE
Sbjct: 168 LHLLPGASKANKLRTKTLRNTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEF 227
Query: 371 IGK 373
IG+
Sbjct: 228 IGE 230
>gi|31881675 synaptotagmin XV isoform a [Homo sapiens]
Length = 421
Score = 174 bits (442), Expect = 1e-43
Identities = 95/282 (33%), Positives = 159/282 (56%), Gaps = 6/282 (2%)
Query: 128 EGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDK 187
E + E + LG+L FS++Y+ +A +L VG+++A L A T P VK++LLPD+
Sbjct: 136 EDKSETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQA--PSETCSPLVKLYLLPDE 193
Query: 188 KKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNT 247
++ ++K RKT NP F+E F F+V + + + L ++Y DR KH ++G+V P+
Sbjct: 194 RRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKN 253
Query: 248 VDLGQPIEE--WRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGL 305
L WRDL+ E P + GD+ L Y +LTV +L AK L+ + G+
Sbjct: 254 ETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGI 313
Query: 306 SDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKL 365
+VK+ LM + K +K KKT+ ++NP +NE+FSF+ ++ + +TV+ +
Sbjct: 314 VSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEG 373
Query: 366 GKNEAIGKIFVG--SNATGTELRHWSDMLANPRRPIAQWHSL 405
K++ +G++ VG G EL HW +ML+ P+ + +WH+L
Sbjct: 374 DKSQQLGRVVVGPYMYTRGRELEHWDEMLSKPKELVKRWHAL 415
Score = 65.1 bits (157), Expect = 1e-10
Identities = 45/148 (30%), Positives = 69/148 (46%), Gaps = 2/148 (1%)
Query: 130 EGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKK- 188
E E + P G LQF L Y+ ++LTV VL+A L + G +VKV L+ K
Sbjct: 269 EAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLMNHNKF 328
Query: 189 -KKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNT 247
K +T ++NP +NETF+FK EL +L + + K +G V V
Sbjct: 329 VKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEGDKSQQLGRVVVGPYM 388
Query: 248 VDLGQPIEEWRDLQGGEKEEPEKLGDIC 275
G+ +E W ++ KE ++ +C
Sbjct: 389 YTRGRELEHWDEMLSKPKELVKRWHALC 416
>gi|47078261 double C2-like domains, alpha [Homo sapiens]
Length = 400
Score = 170 bits (431), Expect = 2e-42
Identities = 113/312 (36%), Positives = 154/312 (49%), Gaps = 31/312 (9%)
Query: 128 EGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPD- 186
E + + + LG L+F L YD + L +L+A L +D G +DPYVK+ LLP
Sbjct: 78 EVDSYDSDDATALGTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLLPGA 137
Query: 187 -KKKKYETKVHRKTLNPAFNETFTFK-VPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVP 244
K K +TK R TLNP +NE T+ + ++ K L +A+ D D+ S ++ IGE++VP
Sbjct: 138 CKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGEIRVP 197
Query: 245 M----------------NTVDLGQPIEEWRDLQG-----GEKEEP-------EKLGDICT 276
+ V L P L+G E E+ E+ G I
Sbjct: 198 LRRLKPSQKKHFNICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLEERGRILL 257
Query: 277 SLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPY 336
SL Y L V IL +L MDV G SDPYVK +L + + K KT VKKKTLNP
Sbjct: 258 SLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPE 317
Query: 337 FNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPR 396
FNE F +EI + + VTV DYD N+ IG + +G A G +HWSD L P
Sbjct: 318 FNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEARKHWSDCLQQPD 377
Query: 397 RPIAQWHSLKPE 408
+ +WH+L E
Sbjct: 378 AALERWHTLTSE 389
Score = 77.0 bits (188), Expect = 3e-14
Identities = 45/123 (36%), Positives = 66/123 (53%), Gaps = 1/123 (0%)
Query: 255 EEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHL 314
E+ ++ + ++ LG + L Y + L IL AK LK MD GL+DPYVK+HL
Sbjct: 74 EDGAEVDSYDSDDATALGTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHL 133
Query: 315 MQNGKRLKKKKTTVKKKTLNPYFNESFSFE-IPFEQIQKVQVVVTVLDYDKLGKNEAIGK 373
+ + K KT ++ TLNP +NE ++ I + I + + V D DKL NE IG+
Sbjct: 134 LPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGE 193
Query: 374 IFV 376
I V
Sbjct: 194 IRV 196
>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
Length = 694
Score = 169 bits (427), Expect = 6e-42
Identities = 107/315 (33%), Positives = 160/315 (50%), Gaps = 27/315 (8%)
Query: 126 EGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLP 185
E E + E LG L+FSL YD + L +++A L +D G +DPYVK+ LLP
Sbjct: 379 EEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLP 438
Query: 186 --DKKKKYETKVHRKTLNPAFNETFTFK-VPYQELGGKTLVMAIYDFDRFSKHDIIGEVK 242
K K TK R T NP +NET + + +++ KTL +++ D D+F ++ IGE +
Sbjct: 439 GASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETR 498
Query: 243 VPMNTVDLGQ------------PIEEW------RDLQGGEKEEPEKLGDI------CTSL 278
+ + Q P++ R + E+E+ E++GDI SL
Sbjct: 499 FSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSL 558
Query: 279 RYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFN 338
Y G L V I+ +L MD G SDP+VK+ L + + K KT +KKKTLNP FN
Sbjct: 559 MYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFN 618
Query: 339 ESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRP 398
E F ++I + K + ++V DYD N+ IG +G +A G L+HW + L N +
Sbjct: 619 EEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKK 678
Query: 399 IAQWHSLKPEEEVDA 413
I +WH L+ E V +
Sbjct: 679 IERWHQLQNENHVSS 693
Score = 79.7 bits (195), Expect = 4e-15
Identities = 45/122 (36%), Positives = 66/122 (54%), Gaps = 1/122 (0%)
Query: 253 PIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKI 312
P EE + + +E LG + SL Y L I++AK LK MD GL+DPYVK+
Sbjct: 375 PEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKL 434
Query: 313 HLMQNGKRLKKKKTTVKKKTLNPYFNESFSFE-IPFEQIQKVQVVVTVLDYDKLGKNEAI 371
HL+ + K +T + T NP +NE+ + I E +Q+ + ++V D DK G NE I
Sbjct: 435 HLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFI 494
Query: 372 GK 373
G+
Sbjct: 495 GE 496
>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
Length = 690
Score = 169 bits (427), Expect = 6e-42
Identities = 107/315 (33%), Positives = 160/315 (50%), Gaps = 27/315 (8%)
Query: 126 EGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLP 185
E E + E LG L+FSL YD + L +++A L +D G +DPYVK+ LLP
Sbjct: 375 EEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLP 434
Query: 186 --DKKKKYETKVHRKTLNPAFNETFTFK-VPYQELGGKTLVMAIYDFDRFSKHDIIGEVK 242
K K TK R T NP +NET + + +++ KTL +++ D D+F ++ IGE +
Sbjct: 435 GASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETR 494
Query: 243 VPMNTVDLGQ------------PIEEW------RDLQGGEKEEPEKLGDI------CTSL 278
+ + Q P++ R + E+E+ E++GDI SL
Sbjct: 495 FSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSL 554
Query: 279 RYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFN 338
Y G L V I+ +L MD G SDP+VK+ L + + K KT +KKKTLNP FN
Sbjct: 555 MYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFN 614
Query: 339 ESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRP 398
E F ++I + K + ++V DYD N+ IG +G +A G L+HW + L N +
Sbjct: 615 EEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKK 674
Query: 399 IAQWHSLKPEEEVDA 413
I +WH L+ E V +
Sbjct: 675 IERWHQLQNENHVSS 689
Score = 79.7 bits (195), Expect = 4e-15
Identities = 45/122 (36%), Positives = 66/122 (54%), Gaps = 1/122 (0%)
Query: 253 PIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKI 312
P EE + + +E LG + SL Y L I++AK LK MD GL+DPYVK+
Sbjct: 371 PEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKL 430
Query: 313 HLMQNGKRLKKKKTTVKKKTLNPYFNESFSFE-IPFEQIQKVQVVVTVLDYDKLGKNEAI 371
HL+ + K +T + T NP +NE+ + I E +Q+ + ++V D DK G NE I
Sbjct: 431 HLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFI 490
Query: 372 GK 373
G+
Sbjct: 491 GE 492
>gi|29366828 synaptotagmin XII [Homo sapiens]
Length = 421
Score = 167 bits (422), Expect = 2e-41
Identities = 87/268 (32%), Positives = 158/268 (58%), Gaps = 2/268 (0%)
Query: 140 LGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKT 199
LG+++ S++YD ++ L V V+Q +L + +++V LLPD++ +++ R
Sbjct: 153 LGQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIVGISRIQRNA 212
Query: 200 LNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLG-QPIEEWR 258
+ F+E F+ + L K+L +++ D ++ G V++ ++ +DL QP W
Sbjct: 213 YSIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDLPLQPFSGWL 272
Query: 259 DLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNG 318
LQ K + +G+I SL Y+PTA +LTV +++AKNL + +DP+VK++L+Q+G
Sbjct: 273 YLQDQNKAA-DAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDG 331
Query: 319 KRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGS 378
+++ KKKT VK+ NP FNE+ F +P +Q + + VTV + G+ + +G + +G
Sbjct: 332 RKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIGP 391
Query: 379 NATGTELRHWSDMLANPRRPIAQWHSLK 406
+A+G HW+ MLA RRP++ WH+++
Sbjct: 392 SASGMGTTHWNQMLATLRRPVSMWHAVR 419
Score = 60.8 bits (146), Expect = 2e-09
Identities = 40/122 (32%), Positives = 64/122 (52%), Gaps = 2/122 (1%)
Query: 132 EEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKK-- 189
++ K + +G++ SL Y A +LTV V++A L + T+DP+VKV+LL D +K
Sbjct: 276 DQNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDGRKMS 335
Query: 190 KYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVD 249
K +T V R NP FNE F VP L +L + + + + D +G V + +
Sbjct: 336 KKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIGPSASG 395
Query: 250 LG 251
+G
Sbjct: 396 MG 397
>gi|193804862 synaptotagmin-like 4 [Homo sapiens]
Length = 671
Score = 146 bits (368), Expect = 4e-35
Identities = 89/277 (32%), Positives = 147/277 (53%), Gaps = 27/277 (9%)
Query: 141 GKLQFSLDYDFQANQLTVGVLQAAELPALDMGGT-SDPYVKVFLLPDKKK--KYETKVHR 197
G++ FSL Y+ Q L V V + +L D S+PYVK +LLPDK + K +T + R
Sbjct: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417
Query: 198 KTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEW 257
T+NP ++ET +++P L +TL +++ RF ++ +GE ++ M++ L + ++
Sbjct: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHC 477
Query: 258 RDLQGGEKEE-----PEKLGDICTSLRYVPTA----------------GKLTVCILEAKN 296
L G E P G++ SL+Y+P + G+L V I EAKN
Sbjct: 478 LPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537
Query: 297 LKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFE-IPFEQIQKVQV 355
L GG SD +VK +L+ + K+KT V KKTLNP++N +F + + E +Q + +
Sbjct: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597
Query: 356 VVTVLDYDKLGKNEAIG--KIFVGSNATGTELRHWSD 390
+TV D + L N+ +G ++ VG+ + E+ W D
Sbjct: 598 ELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMD 634
Score = 68.6 bits (166), Expect = 1e-11
Identities = 39/116 (33%), Positives = 64/116 (55%), Gaps = 3/116 (2%)
Query: 152 QANQLTVGVLQAAELPALDMGGTSDPYVKVFLLP--DKKKKYETKVHRKTLNPAFNETFT 209
+ +L V + +A L A GGTSD +VK +LLP +K K +T V +KTLNP +N TF
Sbjct: 524 EGGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFV 583
Query: 210 FK-VPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGE 264
+ V ++L L + ++D + + +D +G V++ + T + +W D G E
Sbjct: 584 YNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEE 639
>gi|193804860 synaptotagmin-like 4 [Homo sapiens]
Length = 671
Score = 146 bits (368), Expect = 4e-35
Identities = 89/277 (32%), Positives = 147/277 (53%), Gaps = 27/277 (9%)
Query: 141 GKLQFSLDYDFQANQLTVGVLQAAELPALDMGGT-SDPYVKVFLLPDKKK--KYETKVHR 197
G++ FSL Y+ Q L V V + +L D S+PYVK +LLPDK + K +T + R
Sbjct: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417
Query: 198 KTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEW 257
T+NP ++ET +++P L +TL +++ RF ++ +GE ++ M++ L + ++
Sbjct: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHC 477
Query: 258 RDLQGGEKEE-----PEKLGDICTSLRYVPTA----------------GKLTVCILEAKN 296
L G E P G++ SL+Y+P + G+L V I EAKN
Sbjct: 478 LPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537
Query: 297 LKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFE-IPFEQIQKVQV 355
L GG SD +VK +L+ + K+KT V KKTLNP++N +F + + E +Q + +
Sbjct: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597
Query: 356 VVTVLDYDKLGKNEAIG--KIFVGSNATGTELRHWSD 390
+TV D + L N+ +G ++ VG+ + E+ W D
Sbjct: 598 ELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMD 634
Score = 68.6 bits (166), Expect = 1e-11
Identities = 39/116 (33%), Positives = 64/116 (55%), Gaps = 3/116 (2%)
Query: 152 QANQLTVGVLQAAELPALDMGGTSDPYVKVFLLP--DKKKKYETKVHRKTLNPAFNETFT 209
+ +L V + +A L A GGTSD +VK +LLP +K K +T V +KTLNP +N TF
Sbjct: 524 EGGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFV 583
Query: 210 FK-VPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGE 264
+ V ++L L + ++D + + +D +G V++ + T + +W D G E
Sbjct: 584 YNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEE 639
>gi|24308233 synaptotagmin XIII [Homo sapiens]
Length = 426
Score = 144 bits (364), Expect = 1e-34
Identities = 86/267 (32%), Positives = 140/267 (52%), Gaps = 6/267 (2%)
Query: 142 KLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKK-KYETKVHRKTL 200
KL + LDYD Q +L V L+A + G D YV+ + + +T + ++ L
Sbjct: 161 KLHYCLDYDCQKAELFVTRLEAV---TSNHDGGCDCYVQGSVANRTGSVEAQTALKKRQL 217
Query: 201 NPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDL 260
+ + E + +EL TL + + DRFS+H + GE+++ ++ + +W +L
Sbjct: 218 HTTWEEGLVLPLAEEELPTATLTLTLRTCDRFSRHSVAGELRLGLDGTSVPLGAAQWGEL 277
Query: 261 QGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGL--SDPYVKIHLMQNG 318
+ KE G++ S+ Y+P A +L V +++AKNL L D VK+ L
Sbjct: 278 KTSAKEPSAGAGEVLLSISYLPAANRLLVVLIKAKNLHSNQSKELLGKDVSVKVTLKHQA 337
Query: 319 KRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGS 378
++LKKK+T K +NP +NE FE+P + +Q V + VL D G++ A+G +G
Sbjct: 338 RKLKKKQTKRAKHKINPVWNEMIMFELPDDLLQASSVELEVLGQDDSGQSCALGHCSLGL 397
Query: 379 NATGTELRHWSDMLANPRRPIAQWHSL 405
+ +G+E HW +ML NPRR IA WH L
Sbjct: 398 HTSGSERSHWEEMLKNPRRQIAMWHQL 424
>gi|31881667 synaptotagmin XV isoform b [Homo sapiens]
Length = 390
Score = 144 bits (362), Expect = 2e-34
Identities = 82/251 (32%), Positives = 138/251 (54%), Gaps = 4/251 (1%)
Query: 128 EGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDK 187
E + E + LG+L FS++Y+ +A +L VG+++A L A T P VK++LLPD+
Sbjct: 136 EDKSETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQA--PSETCSPLVKLYLLPDE 193
Query: 188 KKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNT 247
++ ++K RKT NP F+E F F+V + + + L ++Y DR KH ++G+V P+
Sbjct: 194 RRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKN 253
Query: 248 VDLGQPIEE--WRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGL 305
L WRDL+ E P + GD+ L Y +LTV +L AK L+ + G+
Sbjct: 254 ETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGI 313
Query: 306 SDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKL 365
+VK+ LM + K +K KKT+ ++NP +NE+FSF+ ++ + +TV+ +
Sbjct: 314 VSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEG 373
Query: 366 GKNEAIGKIFV 376
K ++F+
Sbjct: 374 DKQATTVELFL 384
>gi|239744413 PREDICTED: hypothetical protein LOC390213 [Homo
sapiens]
Length = 431
Score = 126 bits (317), Expect = 3e-29
Identities = 96/297 (32%), Positives = 146/297 (49%), Gaps = 21/297 (7%)
Query: 128 EGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDK 187
E EG+ + + LG L+F+L ++ + L +A L L G++D YVK LLP
Sbjct: 128 EPEGDSD-DSTALGTLEFTLLFEADNSALHCTAHRAKGLKPL-ASGSADAYVKANLLPGA 185
Query: 188 KKKYETKVH--RKTLNPAFNETFTF----------KVPYQELGGKTLVMAIYDF-DRFSK 234
K + + H R T P + ET T+ K +LGG V R +
Sbjct: 186 SKASQLRTHTVRGTRVPVWEETLTYHGFTRQDAECKTLRSDLGGHQAVCVRGPMVQRQWQ 245
Query: 235 HDIIGEVKVPMNTVDLGQPIE-----EWRDLQGGEKEEP-EKLGDICTSLRYVPTAGKLT 288
+GE++VP+ + + E R L+ E E E+ G + SL Y G L
Sbjct: 246 APSLGELRVPLRKLVPNRARSFDICLEKRRLEEVETEVAWEECGHVLLSLCYSSQQGGLL 305
Query: 289 VCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFE 348
V +L +L MD G SDP+V++ L N + K KT+V +KTLNP FNE F + P E
Sbjct: 306 VGVLRCAHLAPMDANGYSDPFVRLFLHPNAGKKSKFKTSVHRKTLNPEFNEEFFYSGPRE 365
Query: 349 QIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSL 405
++ + ++V+V DYD ++ IG + +GS+A+G LRHW + L + + WH L
Sbjct: 366 ELAQKTLLVSVWDYDLGTADDFIGGVQLGSHASGERLRHWLECLGHSDHRLKLWHPL 422
>gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens]
Length = 730
Score = 124 bits (310), Expect = 2e-28
Identities = 89/308 (28%), Positives = 146/308 (47%), Gaps = 51/308 (16%)
Query: 141 GKLQFSLDYDFQANQLTVGVLQAAELPALD-MGGTSDPYVKVFLLPDKKK--KYETKVHR 197
G++ + Y ++ L + V L D +D YVK +LLPDK + K +TK+
Sbjct: 408 GEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRT 467
Query: 198 KTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEW 257
T NP FNET + + + +L +TL ++++ +DRF ++ +GEV++P ++ + P +EW
Sbjct: 468 GT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTDEW 526
Query: 258 RDLQGGEKEEP----EKLGDICTSLRYVP-----------------------------TA 284
LQ + P + G++ LRY+P +
Sbjct: 527 FVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISG 586
Query: 285 GKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFE 344
G L V I EAKNL + GG SD +VK +L+ + + K KT V KK++NP +N +F F
Sbjct: 587 GILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFS 646
Query: 345 -IPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGS-------------NATGTELRHWSD 390
I + I+ V + +T+ D + N +G + + S ++ G E R W
Sbjct: 647 GIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQK 706
Query: 391 MLANPRRP 398
M NP P
Sbjct: 707 MANNPGTP 714
>gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens]
Length = 752
Score = 124 bits (310), Expect = 2e-28
Identities = 89/308 (28%), Positives = 146/308 (47%), Gaps = 51/308 (16%)
Query: 141 GKLQFSLDYDFQANQLTVGVLQAAELPALD-MGGTSDPYVKVFLLPDKKK--KYETKVHR 197
G++ + Y ++ L + V L D +D YVK +LLPDK + K +TK+
Sbjct: 430 GEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRT 489
Query: 198 KTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEW 257
T NP FNET + + + +L +TL ++++ +DRF ++ +GEV++P ++ + P +EW
Sbjct: 490 GT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTDEW 548
Query: 258 RDLQGGEKEEP----EKLGDICTSLRYVP-----------------------------TA 284
LQ + P + G++ LRY+P +
Sbjct: 549 FVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISG 608
Query: 285 GKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFE 344
G L V I EAKNL + GG SD +VK +L+ + + K KT V KK++NP +N +F F
Sbjct: 609 GILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFS 668
Query: 345 -IPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGS-------------NATGTELRHWSD 390
I + I+ V + +T+ D + N +G + + S ++ G E R W
Sbjct: 669 GIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQK 728
Query: 391 MLANPRRP 398
M NP P
Sbjct: 729 MANNPGTP 736
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.135 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,944,086
Number of Sequences: 37866
Number of extensions: 804359
Number of successful extensions: 4109
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 149
Number of HSP's successfully gapped in prelim test: 85
Number of HSP's that attempted gapping in prelim test: 2997
Number of HSP's gapped (non-prelim): 660
length of query: 419
length of database: 18,247,518
effective HSP length: 105
effective length of query: 314
effective length of database: 14,271,588
effective search space: 4481278632
effective search space used: 4481278632
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.