Guide to the Human Genome
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Search of human proteins with 31542498

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31542498 DCP2 decapping enzyme [Homo sapiens]
         (420 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31542498 DCP2 decapping enzyme [Homo sapiens]                      879   0.0  
gi|20149583 nudix-type motif 6 isoform a [Homo sapiens]                40   0.005
gi|40317634 nudix-type motif 4 isoform beta [Homo sapiens]             39   0.009
gi|37221177 nudix-type motif 11 [Homo sapiens]                         36   0.057
gi|40317632 nudix-type motif 4 isoform alpha [Homo sapiens]            36   0.057
gi|41393549 nudix-type motif 10 [Homo sapiens]                         35   0.098
gi|37594461 nudix-type motif 6 isoform b [Homo sapiens]                33   0.48 
gi|5729804 nudix-type motif 3 [Homo sapiens]                           33   0.48 
gi|156523262 hypothetical protein LOC112752 isoform 1 [Homo sapi...    30   3.1  
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]     30   5.4  
gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens]             30   5.4  
gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo ...    30   5.4  
gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo ...    30   5.4  
gi|10835073 N-myristoyltransferase 1 [Homo sapiens]                    30   5.4  
gi|37594464 nudix-type motif 5 [Homo sapiens]                          29   7.0  
gi|58331242 formin homology 2 domain containing 3 [Homo sapiens]       29   9.1  
gi|4506509 regulator of G-protein signalling 12 isoform 2 [Homo ...    29   9.1  
gi|38327601 regulator of G-protein signalling 12 isoform 1 [Homo...    29   9.1  

>gi|31542498 DCP2 decapping enzyme [Homo sapiens]
          Length = 420

 Score =  879 bits (2270), Expect = 0.0
 Identities = 420/420 (100%), Positives = 420/420 (100%)

Query: 1   METKRVEIPGSVLDDLCSRFILHIPSEERDNAIRVCFQIELAHWFYLDFYMQNTPGLPQC 60
           METKRVEIPGSVLDDLCSRFILHIPSEERDNAIRVCFQIELAHWFYLDFYMQNTPGLPQC
Sbjct: 1   METKRVEIPGSVLDDLCSRFILHIPSEERDNAIRVCFQIELAHWFYLDFYMQNTPGLPQC 60

Query: 61  GIRDFAKAVFSHCPFLLPQGEDVEKVLDEWKEYKMGVPTYGAIILDETLENVLLVQGYLA 120
           GIRDFAKAVFSHCPFLLPQGEDVEKVLDEWKEYKMGVPTYGAIILDETLENVLLVQGYLA
Sbjct: 61  GIRDFAKAVFSHCPFLLPQGEDVEKVLDEWKEYKMGVPTYGAIILDETLENVLLVQGYLA 120

Query: 121 KSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPGI 180
           KSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPGI
Sbjct: 121 KSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPGI 180

Query: 181 PKDTKFNPKTRREIRNIEWFSIEKLPCHRNDMTPKSKLGLAPNKFFMAIPFIRPLRDWLS 240
           PKDTKFNPKTRREIRNIEWFSIEKLPCHRNDMTPKSKLGLAPNKFFMAIPFIRPLRDWLS
Sbjct: 181 PKDTKFNPKTRREIRNIEWFSIEKLPCHRNDMTPKSKLGLAPNKFFMAIPFIRPLRDWLS 240

Query: 241 RRFGDSSDSDNGFSSTGSTPAKPTVEKLSRTKFRHSQQLFPDGSPGDQWVKHRQPLQQKP 300
           RRFGDSSDSDNGFSSTGSTPAKPTVEKLSRTKFRHSQQLFPDGSPGDQWVKHRQPLQQKP
Sbjct: 241 RRFGDSSDSDNGFSSTGSTPAKPTVEKLSRTKFRHSQQLFPDGSPGDQWVKHRQPLQQKP 300

Query: 301 YNNHSEMSDLLKGKNQSMRGNGRKQYQDSPNQKKRTNGLQPAKQQNSLMKCEKKLHPRKL 360
           YNNHSEMSDLLKGKNQSMRGNGRKQYQDSPNQKKRTNGLQPAKQQNSLMKCEKKLHPRKL
Sbjct: 301 YNNHSEMSDLLKGKNQSMRGNGRKQYQDSPNQKKRTNGLQPAKQQNSLMKCEKKLHPRKL 360

Query: 361 QDNFETDAVYDLPSSSEDQLLEHAEGQPVACNGHCKFPFSSRAFLSFKFDHNAIMKILDL 420
           QDNFETDAVYDLPSSSEDQLLEHAEGQPVACNGHCKFPFSSRAFLSFKFDHNAIMKILDL
Sbjct: 361 QDNFETDAVYDLPSSSEDQLLEHAEGQPVACNGHCKFPFSSRAFLSFKFDHNAIMKILDL 420


>gi|20149583 nudix-type motif 6 isoform a [Homo sapiens]
          Length = 316

 Score = 39.7 bits (91), Expect = 0.005
 Identities = 25/65 (38%), Positives = 34/65 (52%), Gaps = 4/65 (6%)

Query: 87  LDEWKEYKMGVPTYGAIILDETLENVLLVQGY-LAKSGWGFPKGKVNKEEAPHDCAAREV 145
           L  +  +++GV      + DE+   +L+VQ     K+ W FP G    EE   D A REV
Sbjct: 136 LPGYASHQVGV---AGAVFDESTRKILVVQDRNKLKNMWKFPGGLSEPEEDIGDTAVREV 192

Query: 146 FEETG 150
           FEETG
Sbjct: 193 FEETG 197


>gi|40317634 nudix-type motif 4 isoform beta [Homo sapiens]
          Length = 181

 Score = 38.9 bits (89), Expect = 0.009
 Identities = 39/135 (28%), Positives = 58/135 (42%), Gaps = 16/135 (11%)

Query: 107 ETLENVLLVQGYLAKSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELR 166
           E  + VLLV        W  P G +  EE P   A REV+EE G  +K  + +   I  +
Sbjct: 29  EQEDEVLLVSSSRYPDQWIVPGGGMEPEEEPGGAAVREVYEEAG--VKGKLGRLLGIFEQ 86

Query: 167 INDQLARLYI----IPGIPKDTKFNPKTRREIRNIEWFSIEK----LPCHR---NDMTPK 215
             D+  R Y+    +  I +D + +    R+    EWF +E     L CH+    +   K
Sbjct: 87  NQDRKHRTYVYVLTVTEILEDWEDSVNIGRK---REWFKVEDAIKVLQCHKPVHAEYLEK 143

Query: 216 SKLGLAPNKFFMAIP 230
            KLG +P      +P
Sbjct: 144 LKLGCSPANGNSTVP 158


>gi|37221177 nudix-type motif 11 [Homo sapiens]
          Length = 164

 Score = 36.2 bits (82), Expect = 0.057
 Identities = 36/124 (29%), Positives = 53/124 (42%), Gaps = 10/124 (8%)

Query: 107 ETLENVLLVQGYLAKSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELR 166
           E  + VLLV        W  P G +  EE P   A REV+EE G  +K  + +   +  +
Sbjct: 28  EREDEVLLVSSSRYPDRWIVPGGGMEPEEEPGGAAVREVYEEAG--VKGKLGRLLGVFEQ 85

Query: 167 INDQLARLYIIPGIPKDTKFNPKTRREI-RNIEWFSIEK----LPCHR---NDMTPKSKL 218
             D+  R Y+      +   + +    I R  EWF +E     L CH+    +   K KL
Sbjct: 86  NQDRKHRTYVYVLTVTELLEDWEDSVSIGRKREWFKVEDAIKVLQCHKPVHAEYLEKLKL 145

Query: 219 GLAP 222
           G +P
Sbjct: 146 GGSP 149


>gi|40317632 nudix-type motif 4 isoform alpha [Homo sapiens]
          Length = 180

 Score = 36.2 bits (82), Expect = 0.057
 Identities = 39/135 (28%), Positives = 57/135 (42%), Gaps = 17/135 (12%)

Query: 107 ETLENVLLVQGYLAKSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELR 166
           E  + VLLV        W  P G +  EE P   A REV+EE G  +K  + +   I   
Sbjct: 29  EQEDEVLLVSSSRYPDQWIVPGGGMEPEEEPGGAAVREVYEEAG--VKGKLGRLLGI-FE 85

Query: 167 INDQLARLYI----IPGIPKDTKFNPKTRREIRNIEWFSIEK----LPCHR---NDMTPK 215
             D+  R Y+    +  I +D + +    R+    EWF +E     L CH+    +   K
Sbjct: 86  NQDRKHRTYVYVLTVTEILEDWEDSVNIGRK---REWFKVEDAIKVLQCHKPVHAEYLEK 142

Query: 216 SKLGLAPNKFFMAIP 230
            KLG +P      +P
Sbjct: 143 LKLGCSPANGNSTVP 157


>gi|41393549 nudix-type motif 10 [Homo sapiens]
          Length = 164

 Score = 35.4 bits (80), Expect = 0.098
 Identities = 36/124 (29%), Positives = 52/124 (41%), Gaps = 10/124 (8%)

Query: 107 ETLENVLLVQGYLAKSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELR 166
           E  + VLLV        W  P G +  EE P   A REV+EE G  +K  + +   +  +
Sbjct: 28  EREDEVLLVSSSRYPDRWIVPGGGMEPEEEPGGAAVREVYEEAG--VKGKLGRLLGVFEQ 85

Query: 167 INDQLARLYIIPGIPKDTKFNPKTRREI-RNIEWFSIEK----LPCHR---NDMTPKSKL 218
             D   R Y+      +   + +    I R  EWF +E     L CH+    +   K KL
Sbjct: 86  NQDPKHRTYVYVLTVTELLEDWEDSVSIGRKREWFKVEDAIKVLQCHKPVHAEYLEKLKL 145

Query: 219 GLAP 222
           G +P
Sbjct: 146 GGSP 149


>gi|37594461 nudix-type motif 6 isoform b [Homo sapiens]
          Length = 147

 Score = 33.1 bits (74), Expect = 0.48
 Identities = 16/27 (59%), Positives = 16/27 (59%)

Query: 124 WGFPKGKVNKEEAPHDCAAREVFEETG 150
           W FP G    EE   D A REVFEETG
Sbjct: 2   WKFPGGLSEPEEDIGDTAVREVFEETG 28


>gi|5729804 nudix-type motif 3 [Homo sapiens]
          Length = 172

 Score = 33.1 bits (74), Expect = 0.48
 Identities = 19/44 (43%), Positives = 21/44 (47%)

Query: 107 ETLENVLLVQGYLAKSGWGFPKGKVNKEEAPHDCAAREVFEETG 150
           E+ E VLLV        W  P G +  EE P   A REV EE G
Sbjct: 29  ESEEEVLLVSSSRHPDRWIVPGGGMEPEEEPSVAAVREVCEEAG 72


>gi|156523262 hypothetical protein LOC112752 isoform 1 [Homo
           sapiens]
          Length = 213

 Score = 30.4 bits (67), Expect = 3.1
 Identities = 21/77 (27%), Positives = 30/77 (38%), Gaps = 9/77 (11%)

Query: 293 RQPLQQKPYNNHSEMSDLLKGKNQSMRGNGRKQYQDSPNQK---------KRTNGLQPAK 343
           R  + ++     ++  + L GKN S+   G       P  +         K +NG Q  K
Sbjct: 19  RAKMGRRAQQESAQAENHLNGKNSSLTLTGETSSAKLPRCRQGGWAGDSVKASNGTQTGK 78

Query: 344 QQNSLMKCEKKLHPRKL 360
           QQ  L  C  K H R L
Sbjct: 79  QQLDLNACYHKTHHRDL 95


>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
          Length = 494

 Score = 29.6 bits (65), Expect = 5.4
 Identities = 26/125 (20%), Positives = 47/125 (37%), Gaps = 7/125 (5%)

Query: 262 KPTVEKLSRTKFRHSQQLFPDGSPGDQ----WVKHRQPLQQKPYNNHSEMSDLLKGKNQS 317
           K  +EKL  T+    +    +  PG +    + + R   + +  + HS  S    G ++S
Sbjct: 154 KRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKS 213

Query: 318 MRGNGRKQYQDSPNQKKRTNGLQPAKQQNSLMKCEKKLHPRKLQDNFETDAVYDLPSSSE 377
                R + +     + ++       Q  S  K EK   P K +    + +     S S+
Sbjct: 214 SHSKSRSRSRSGSRSRSKSRS---RSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSK 270

Query: 378 DQLLE 382
           DQ  E
Sbjct: 271 DQAEE 275


>gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens]
          Length = 1950

 Score = 29.6 bits (65), Expect = 5.4
 Identities = 24/99 (24%), Positives = 41/99 (41%), Gaps = 4/99 (4%)

Query: 240 SRRFGDSSDSDNGFSSTGSTPAKPTVEKLSRTKFRHSQQLFPDGSPGDQWVKHRQPLQQK 299
           SR+FG +  S+NG   T  + +    E L     +  Q+ F  G+ G  W  + Q   + 
Sbjct: 369 SRKFGGNELSENGIKVTRESSSSDLAENLGFGLEKFGQKGF--GTSGSGW--NEQSSSKS 424

Query: 300 PYNNHSEMSDLLKGKNQSMRGNGRKQYQDSPNQKKRTNG 338
             +   E S L +      +G     ++DS + +   NG
Sbjct: 425 DVSGAVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNG 463


>gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo
           sapiens]
          Length = 2134

 Score = 29.6 bits (65), Expect = 5.4
 Identities = 24/99 (24%), Positives = 41/99 (41%), Gaps = 4/99 (4%)

Query: 240 SRRFGDSSDSDNGFSSTGSTPAKPTVEKLSRTKFRHSQQLFPDGSPGDQWVKHRQPLQQK 299
           SR+FG +  S+NG   T  + +    E L     +  Q+ F  G+ G  W  + Q   + 
Sbjct: 380 SRKFGGNELSENGIKVTRESSSSDLAENLGFGLEKFGQKGF--GTSGSGW--NEQSSSKS 435

Query: 300 PYNNHSEMSDLLKGKNQSMRGNGRKQYQDSPNQKKRTNG 338
             +   E S L +      +G     ++DS + +   NG
Sbjct: 436 DVSGAVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNG 474


>gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo
           sapiens]
          Length = 2134

 Score = 29.6 bits (65), Expect = 5.4
 Identities = 24/99 (24%), Positives = 41/99 (41%), Gaps = 4/99 (4%)

Query: 240 SRRFGDSSDSDNGFSSTGSTPAKPTVEKLSRTKFRHSQQLFPDGSPGDQWVKHRQPLQQK 299
           SR+FG +  S+NG   T  + +    E L     +  Q+ F  G+ G  W  + Q   + 
Sbjct: 380 SRKFGGNELSENGIKVTRESSSSDLAENLGFGLEKFGQKGF--GTSGSGW--NEQSSSKS 435

Query: 300 PYNNHSEMSDLLKGKNQSMRGNGRKQYQDSPNQKKRTNG 338
             +   E S L +      +G     ++DS + +   NG
Sbjct: 436 DVSGAVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNG 474


>gi|10835073 N-myristoyltransferase 1 [Homo sapiens]
          Length = 496

 Score = 29.6 bits (65), Expect = 5.4
 Identities = 18/57 (31%), Positives = 27/57 (47%), Gaps = 5/57 (8%)

Query: 320 GNGRKQYQDSPNQKKRT---NGLQPAKQQNSLMKCEKKLHPRKLQDNFETDAVYDLP 373
           GNG +   D  N++  +    GL PA    +  K +KK   +K +   ETD+  D P
Sbjct: 24  GNGHEHCSDCENEEDNSYNRGGLSPANDTGA--KKKKKKQKKKKEKGSETDSAQDQP 78


>gi|37594464 nudix-type motif 5 [Homo sapiens]
          Length = 219

 Score = 29.3 bits (64), Expect = 7.0
 Identities = 19/53 (35%), Positives = 28/53 (52%), Gaps = 5/53 (9%)

Query: 104 ILDETL--ENVLLVQGYLAKSGW---GFPKGKVNKEEAPHDCAAREVFEETGF 151
           +L  TL  E ++LV+ +    G     FP G ++  E P   A RE+ EETG+
Sbjct: 67  VLQRTLHYECIVLVKQFRPPMGGYCIEFPAGLIDDGETPEAAALRELEEETGY 119


>gi|58331242 formin homology 2 domain containing 3 [Homo sapiens]
          Length = 1439

 Score = 28.9 bits (63), Expect = 9.1
 Identities = 35/158 (22%), Positives = 61/158 (38%), Gaps = 4/158 (2%)

Query: 232 IRPLRDWLSRRFGDSSDSDNGFSSTGSTPAKPTVEKLSRTKFRHSQQLFPDGSPGDQWVK 291
           +R LR+  S  FG++S   +  SS  S P  PT   +S  +    ++  P G     + +
Sbjct: 393 VRDLREKYSN-FGNNSYHSSRPSSGSSVPTTPT-SSVSPPQEARLERSSPSGLLTSSFRQ 450

Query: 292 HRQPLQQKPYNNHSEMSDLLKGKNQSMRGNGRKQYQDS-PNQKKRTNGLQPAKQQNSLMK 350
           H++ L  +      E  + L+   +  R    + Y D    Q++         +Q +  +
Sbjct: 451 HQESLAAERERRRQEREERLQRIEREERNKFSRDYLDKREEQRQAREERYKYLEQLAAEE 510

Query: 351 CEKKLHPRKLQDNFETDAVYDLPSSSEDQLLEHAEGQP 388
            EK+L  R +      D   DL S +    L      P
Sbjct: 511 HEKELRSRSVSRG-RADLSLDLTSPAAPACLAPLSHSP 547


>gi|4506509 regulator of G-protein signalling 12 isoform 2 [Homo
           sapiens]
          Length = 1376

 Score = 28.9 bits (63), Expect = 9.1
 Identities = 11/39 (28%), Positives = 24/39 (61%)

Query: 81  EDVEKVLDEWKEYKMGVPTYGAIILDETLENVLLVQGYL 119
           E++ KV+ +   + +G+ ++    LD ++ NV ++ GYL
Sbjct: 197 EEISKVIHDDSVFSIGLESHDDFALDASILNVAMIVGYL 235


>gi|38327601 regulator of G-protein signalling 12 isoform 1 [Homo
           sapiens]
          Length = 1447

 Score = 28.9 bits (63), Expect = 9.1
 Identities = 11/39 (28%), Positives = 24/39 (61%)

Query: 81  EDVEKVLDEWKEYKMGVPTYGAIILDETLENVLLVQGYL 119
           E++ KV+ +   + +G+ ++    LD ++ NV ++ GYL
Sbjct: 197 EEISKVIHDDSVFSIGLESHDDFALDASILNVAMIVGYL 235


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.137    0.426 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,871,954
Number of Sequences: 37866
Number of extensions: 868548
Number of successful extensions: 2063
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 2053
Number of HSP's gapped (non-prelim): 19
length of query: 420
length of database: 18,247,518
effective HSP length: 105
effective length of query: 315
effective length of database: 14,271,588
effective search space: 4495550220
effective search space used: 4495550220
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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