Guide to the Human Genome
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Search of human proteins with 31542319

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31542319 epsilon subunit of coatomer protein complex isoform
a [Homo sapiens]
         (308 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31542319 epsilon subunit of coatomer protein complex isoform ...   611   e-175
gi|40805825 epsilon subunit of coatomer protein complex isoform ...   486   e-137
gi|40805827 epsilon subunit of coatomer protein complex isoform ...   481   e-136
gi|5803167 splicing factor 3a, subunit 3 [Homo sapiens]                30   3.5  
gi|89111119 metallothionein-like 5, testis-specific isoform b [H...    29   4.6  
gi|40806200 metallothionein-like 5, testis-specific isoform a [H...    29   4.6  
gi|20665034 tenascin XB isoform 2 [Homo sapiens]                       29   6.0  
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]            29   6.0  
gi|83415184 transmembrane and tetratricopeptide repeat containin...    29   6.0  
gi|38198663 potassium channel tetramerisation domain containing ...    28   7.9  

>gi|31542319 epsilon subunit of coatomer protein complex isoform a
           [Homo sapiens]
          Length = 308

 Score =  611 bits (1575), Expect = e-175
 Identities = 308/308 (100%), Positives = 308/308 (100%)

Query: 1   MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY 60
           MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY
Sbjct: 1   MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY 60

Query: 61  LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRRDSIVAELDREMSRSVDVTNTTFL 120
           LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRRDSIVAELDREMSRSVDVTNTTFL
Sbjct: 61  LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRRDSIVAELDREMSRSVDVTNTTFL 120

Query: 121 LMAASIYLHDQNPDAALRALHQGDSLECTAMTVQILLKLDRLDLARKELKRMQDLDEDAT 180
           LMAASIYLHDQNPDAALRALHQGDSLECTAMTVQILLKLDRLDLARKELKRMQDLDEDAT
Sbjct: 121 LMAASIYLHDQNPDAALRALHQGDSLECTAMTVQILLKLDRLDLARKELKRMQDLDEDAT 180

Query: 181 LTQLATAWVSLATGGEKLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQGRWEAAEGLLQ 240
           LTQLATAWVSLATGGEKLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQGRWEAAEGLLQ
Sbjct: 181 LTQLATAWVSLATGGEKLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQGRWEAAEGLLQ 240

Query: 241 EALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRL 300
           EALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRL
Sbjct: 241 EALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRL 300

Query: 301 VLQYAPSA 308
           VLQYAPSA
Sbjct: 301 VLQYAPSA 308


>gi|40805825 epsilon subunit of coatomer protein complex isoform b
           [Homo sapiens]
          Length = 257

 Score =  486 bits (1251), Expect = e-137
 Identities = 256/308 (83%), Positives = 256/308 (83%), Gaps = 51/308 (16%)

Query: 1   MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY 60
           MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY
Sbjct: 1   MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY 60

Query: 61  LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRRDSIVAELDREMSRSVDVTNTTFL 120
           LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESR                        
Sbjct: 61  LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRS----------------------- 97

Query: 121 LMAASIYLHDQNPDAALRALHQGDSLECTAMTVQILLKLDRLDLARKELKRMQDLDEDAT 180
                                       TAMTVQILLKLDRLDLARKELKRMQDLDEDAT
Sbjct: 98  ----------------------------TAMTVQILLKLDRLDLARKELKRMQDLDEDAT 129

Query: 181 LTQLATAWVSLATGGEKLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQGRWEAAEGLLQ 240
           LTQLATAWVSLATGGEKLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQGRWEAAEGLLQ
Sbjct: 130 LTQLATAWVSLATGGEKLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQGRWEAAEGLLQ 189

Query: 241 EALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRL 300
           EALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRL
Sbjct: 190 EALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRL 249

Query: 301 VLQYAPSA 308
           VLQYAPSA
Sbjct: 250 VLQYAPSA 257


>gi|40805827 epsilon subunit of coatomer protein complex isoform c
           [Homo sapiens]
          Length = 256

 Score =  481 bits (1237), Expect = e-136
 Identities = 256/308 (83%), Positives = 256/308 (83%), Gaps = 52/308 (16%)

Query: 1   MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY 60
           MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY
Sbjct: 1   MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY 60

Query: 61  LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRRDSIVAELDREMSRSVDVTNTTFL 120
           LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRRDSIVAELDREMSRSVDVTNTTFL
Sbjct: 61  LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRRDSIVAELDREMSRSVDVTNTTFL 120

Query: 121 LMAASIYLHDQNPDAALRALHQGDSLECTAMTVQILLKLDRLDLARKELKRMQDLDEDAT 180
           LMAASIYLHDQNPDAALRALHQGDSLECTAMTVQILLKLDRLDLARKELKRMQDLDEDAT
Sbjct: 121 LMAASIYLHDQNPDAALRALHQGDSLECTAMTVQILLKLDRLDLARKELKRMQDLDEDAT 180

Query: 181 LTQLATAWVSLATGGEKLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQGRWEAAEGLLQ 240
           LTQLATAWVSLAT                                               
Sbjct: 181 LTQLATAWVSLAT----------------------------------------------- 193

Query: 241 EALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRL 300
                DSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRL
Sbjct: 194 -----DSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRL 248

Query: 301 VLQYAPSA 308
           VLQYAPSA
Sbjct: 249 VLQYAPSA 256


>gi|5803167 splicing factor 3a, subunit 3 [Homo sapiens]
          Length = 501

 Score = 29.6 bits (65), Expect = 3.5
 Identities = 26/92 (28%), Positives = 37/92 (40%), Gaps = 10/92 (10%)

Query: 196 EKLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQGRWEAAEGLLQEALDKDSGYPETLVN 255
           E+L D   + +EM  K S     +N        Q R+    G L++  D   G  +  +N
Sbjct: 16  ERLMDV--MAKEMLTKKSTLRDQINSDHRTRAMQDRYMEVSGNLRDLYDDKDGLRKEELN 73

Query: 256 LIVLSQHLGKPPEVTNRY--LSQLKDAHRSHP 285
            I        P E    Y  L Q+K+ HR HP
Sbjct: 74  AI------SGPNEFAEFYNRLKQIKEFHRKHP 99


>gi|89111119 metallothionein-like 5, testis-specific isoform b [Homo
           sapiens]
          Length = 306

 Score = 29.3 bits (64), Expect = 4.6
 Identities = 34/126 (26%), Positives = 49/126 (38%), Gaps = 24/126 (19%)

Query: 177 EDATLTQL-------ATAWVSLATGGEKLQDAYYIFQEM----ADKCSPTLLLLN----- 220
           EDA +T+L       A+  + L    +  +D +++F+E     AD   P L   N     
Sbjct: 14  EDAMVTELLSPEGPFASENIGLKAPVKYEEDEFHVFKEAYLGPADPKEPVLHAFNPALGA 73

Query: 221 ---GQAACHMAQGRWEAAEGLLQEALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQL 277
              GQ    +A G  +  E      L +  G PE      V      +PP     +LS L
Sbjct: 74  DCKGQVKAKLAGGDSDGGE-----LLGEYPGIPELSALEDVALLQAPQPPACNVHFLSSL 128

Query: 278 KDAHRS 283
             AHRS
Sbjct: 129 LPAHRS 134


>gi|40806200 metallothionein-like 5, testis-specific isoform a [Homo
           sapiens]
          Length = 508

 Score = 29.3 bits (64), Expect = 4.6
 Identities = 34/126 (26%), Positives = 49/126 (38%), Gaps = 24/126 (19%)

Query: 177 EDATLTQL-------ATAWVSLATGGEKLQDAYYIFQEM----ADKCSPTLLLLN----- 220
           EDA +T+L       A+  + L    +  +D +++F+E     AD   P L   N     
Sbjct: 14  EDAMVTELLSPEGPFASENIGLKAPVKYEEDEFHVFKEAYLGPADPKEPVLHAFNPALGA 73

Query: 221 ---GQAACHMAQGRWEAAEGLLQEALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQL 277
              GQ    +A G  +  E      L +  G PE      V      +PP     +LS L
Sbjct: 74  DCKGQVKAKLAGGDSDGGE-----LLGEYPGIPELSALEDVALLQAPQPPACNVHFLSSL 128

Query: 278 KDAHRS 283
             AHRS
Sbjct: 129 LPAHRS 134


>gi|20665034 tenascin XB isoform 2 [Homo sapiens]
          Length = 673

 Score = 28.9 bits (63), Expect = 6.0
 Identities = 24/94 (25%), Positives = 42/94 (44%), Gaps = 15/94 (15%)

Query: 137 LRALHQGDSLECTAMTVQILLKLDRLDLARKELKRMQDLDEDATLTQLATAWVSLATGGE 196
           LR  H+ DS++ TA T+  +L+  R DL   E++           T     W+   +  +
Sbjct: 165 LRGPHKADSIQGTARTLSPVLESPR-DLQFSEIRE----------TSAKVNWMPPPSRAD 213

Query: 197 KLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQG 230
             + +Y    ++AD   P  + ++GQA     QG
Sbjct: 214 SFKVSY----QLADGGEPQSVQVDGQARTQKLQG 243


>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
          Length = 4242

 Score = 28.9 bits (63), Expect = 6.0
 Identities = 24/94 (25%), Positives = 42/94 (44%), Gaps = 15/94 (15%)

Query: 137  LRALHQGDSLECTAMTVQILLKLDRLDLARKELKRMQDLDEDATLTQLATAWVSLATGGE 196
            LR  H+ DS++ TA T+  +L+  R DL   E++           T     W+   +  +
Sbjct: 3734 LRGPHKADSIQGTARTLSPVLESPR-DLQFSEIRE----------TSAKVNWMPPPSRAD 3782

Query: 197  KLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQG 230
              + +Y    ++AD   P  + ++GQA     QG
Sbjct: 3783 SFKVSY----QLADGGEPQSVQVDGQARTQKLQG 3812


>gi|83415184 transmembrane and tetratricopeptide repeat containing 1
           [Homo sapiens]
          Length = 774

 Score = 28.9 bits (63), Expect = 6.0
 Identities = 27/104 (25%), Positives = 45/104 (43%), Gaps = 3/104 (2%)

Query: 183 QLATAWVSLAT---GGEKLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQGRWEAAEGLL 239
           + A A+ SLA+     E+ ++A  I+Q     C  +  L N      +  G  E A    
Sbjct: 472 EFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLPEKAVAHY 531

Query: 240 QEALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRS 283
           Q+A+     +   +VNL  L + LG+       Y   L+ AH++
Sbjct: 532 QQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVAHKA 575


>gi|38198663 potassium channel tetramerisation domain containing 8
           [Homo sapiens]
          Length = 473

 Score = 28.5 bits (62), Expect = 7.9
 Identities = 25/99 (25%), Positives = 39/99 (39%), Gaps = 3/99 (3%)

Query: 3   PPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAYLA 62
           P  PG   GG G   +  D ++ F    Y+      +  +  +  R V R +   R  LA
Sbjct: 187 PSGPGAHGGGGGGGAQ--DKRSGFLTLGYRGSYTTVRDNQADAKFRRVARIMVCGRIALA 244

Query: 63  QRKFGVVLDEIK-PSSAPELQAVRMFADYLAHESRRDSI 100
           +  FG  L+E + P   PE    R +  +   E   D +
Sbjct: 245 KEVFGDTLNESRDPDRQPEKYTSRFYLKFTYLEQAFDRL 283


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.132    0.379 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,770,316
Number of Sequences: 37866
Number of extensions: 486833
Number of successful extensions: 1453
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1447
Number of HSP's gapped (non-prelim): 12
length of query: 308
length of database: 18,247,518
effective HSP length: 102
effective length of query: 206
effective length of database: 14,385,186
effective search space: 2963348316
effective search space used: 2963348316
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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