Search of human proteins with 31542315

Search of human proteins with 31542315

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31542315 CCR4-NOT transcription complex, subunit 8 [Homo
sapiens]
         (292 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31542315 CCR4-NOT transcription complex, subunit 8 [Homo sapi...   590   e-169
gi|85067507 CCR4-NOT transcription complex, subunit 7 isoform 1 ...   456   e-129
gi|85067505 CCR4-NOT transcription complex, subunit 7 isoform 2 ...   413   e-115
gi|4505611 poly(A)-specific ribonuclease (deadenylation nuclease...    35   0.060
gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens]      32   0.86 
gi|226371750 terminal uridylyl transferase 1, U6 snRNA-specific ...    31   1.1  
gi|52630326 chromodomain helicase DNA binding protein 3 isoform ...    31   1.5  
gi|52630322 chromodomain helicase DNA binding protein 3 isoform ...    31   1.5  
gi|158420731 chromodomain helicase DNA binding protein 3 isoform...    31   1.5  
gi|51599156 chromodomain helicase DNA binding protein 4 [Homo sa...    30   2.5  
gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa...    30   2.5  
gi|158634482 poly (ADP-ribose) polymerase family, member 3 isofo...    28   7.3  
gi|158634478 poly (ADP-ribose) polymerase family, member 3 isofo...    28   7.3  

>gi|31542315 CCR4-NOT transcription complex, subunit 8 [Homo
           sapiens]
          Length = 292

 Score =  590 bits (1520), Expect = e-169
 Identities = 292/292 (100%), Positives = 292/292 (100%)

Query: 1   MPAALVENSQVICEVWASNLEEEMRKIREIVLSYSYIAMDTEFPGVVVRPIGEFRSSIDY 60
           MPAALVENSQVICEVWASNLEEEMRKIREIVLSYSYIAMDTEFPGVVVRPIGEFRSSIDY
Sbjct: 1   MPAALVENSQVICEVWASNLEEEMRKIREIVLSYSYIAMDTEFPGVVVRPIGEFRSSIDY 60

Query: 61  QYQLLRCNVDLLKIIQLGLTFTNEKGEYPSGINTWQFNFKFNLTEDMYSQDSIDLLANSG 120
           QYQLLRCNVDLLKIIQLGLTFTNEKGEYPSGINTWQFNFKFNLTEDMYSQDSIDLLANSG
Sbjct: 61  QYQLLRCNVDLLKIIQLGLTFTNEKGEYPSGINTWQFNFKFNLTEDMYSQDSIDLLANSG 120

Query: 121 LQFQKHEEEGIDTLHFAELLMTSGVVLCDNVKWLSFHSGYDFGYMVKLLTDSRLPEEEHE 180
           LQFQKHEEEGIDTLHFAELLMTSGVVLCDNVKWLSFHSGYDFGYMVKLLTDSRLPEEEHE
Sbjct: 121 LQFQKHEEEGIDTLHFAELLMTSGVVLCDNVKWLSFHSGYDFGYMVKLLTDSRLPEEEHE 180

Query: 181 FFHILNLFFPSIYDVKYLMKSCKNLKGGLQEVADQLDLQRIGRQHQAGSDSLLTGMAFFR 240
           FFHILNLFFPSIYDVKYLMKSCKNLKGGLQEVADQLDLQRIGRQHQAGSDSLLTGMAFFR
Sbjct: 181 FFHILNLFFPSIYDVKYLMKSCKNLKGGLQEVADQLDLQRIGRQHQAGSDSLLTGMAFFR 240

Query: 241 MKELFFEDSIDDAKYCGRLYGLGTGVAQKQNEDVDSAQEKMSILAIINNMQQ 292
           MKELFFEDSIDDAKYCGRLYGLGTGVAQKQNEDVDSAQEKMSILAIINNMQQ
Sbjct: 241 MKELFFEDSIDDAKYCGRLYGLGTGVAQKQNEDVDSAQEKMSILAIINNMQQ 292


>gi|85067507 CCR4-NOT transcription complex, subunit 7 isoform 1
           [Homo sapiens]
          Length = 285

 Score =  456 bits (1174), Expect = e-129
 Identities = 215/280 (76%), Positives = 251/280 (89%)

Query: 1   MPAALVENSQVICEVWASNLEEEMRKIREIVLSYSYIAMDTEFPGVVVRPIGEFRSSIDY 60
           MPAA V++SQ ICEVWA NL+EEM+KIR+++  Y+Y+AMDTEFPGVV RPIGEFRS+ DY
Sbjct: 1   MPAATVDHSQRICEVWACNLDEEMKKIRQVIRKYNYVAMDTEFPGVVARPIGEFRSNADY 60

Query: 61  QYQLLRCNVDLLKIIQLGLTFTNEKGEYPSGINTWQFNFKFNLTEDMYSQDSIDLLANSG 120
           QYQLLRCNVDLLKIIQLGLTF NE+GEYP G +TWQFNFKFNLTEDMY+QDSI+LL  SG
Sbjct: 61  QYQLLRCNVDLLKIIQLGLTFMNEQGEYPPGTSTWQFNFKFNLTEDMYAQDSIELLTTSG 120

Query: 121 LQFQKHEEEGIDTLHFAELLMTSGVVLCDNVKWLSFHSGYDFGYMVKLLTDSRLPEEEHE 180
           +QF+KHEEEGI+T +FAELLMTSGVVLC+ VKWLSFHSGYDFGY++K+LT+S LPEEE +
Sbjct: 121 IQFKKHEEEGIETQYFAELLMTSGVVLCEGVKWLSFHSGYDFGYLIKILTNSNLPEEELD 180

Query: 181 FFHILNLFFPSIYDVKYLMKSCKNLKGGLQEVADQLDLQRIGRQHQAGSDSLLTGMAFFR 240
           FF IL LFFP IYDVKYLMKSCKNLKGGLQEVA+QL+L+RIG QHQAGSDSLLTGMAFF+
Sbjct: 181 FFEILRLFFPVIYDVKYLMKSCKNLKGGLQEVAEQLELERIGPQHQAGSDSLLTGMAFFK 240

Query: 241 MKELFFEDSIDDAKYCGRLYGLGTGVAQKQNEDVDSAQEK 280
           M+E+FFED IDDAKYCG LYGLG+G +  QN   ++ +E+
Sbjct: 241 MREMFFEDHIDDAKYCGHLYGLGSGSSYVQNGTGNAYEEE 280


>gi|85067505 CCR4-NOT transcription complex, subunit 7 isoform 2
           [Homo sapiens]
          Length = 244

 Score =  413 bits (1061), Expect = e-115
 Identities = 194/244 (79%), Positives = 224/244 (91%)

Query: 1   MPAALVENSQVICEVWASNLEEEMRKIREIVLSYSYIAMDTEFPGVVVRPIGEFRSSIDY 60
           MPAA V++SQ ICEVWA NL+EEM+KIR+++  Y+Y+AMDTEFPGVV RPIGEFRS+ DY
Sbjct: 1   MPAATVDHSQRICEVWACNLDEEMKKIRQVIRKYNYVAMDTEFPGVVARPIGEFRSNADY 60

Query: 61  QYQLLRCNVDLLKIIQLGLTFTNEKGEYPSGINTWQFNFKFNLTEDMYSQDSIDLLANSG 120
           QYQLLRCNVDLLKIIQLGLTF NE+GEYP G +TWQFNFKFNLTEDMY+QDSI+LL  SG
Sbjct: 61  QYQLLRCNVDLLKIIQLGLTFMNEQGEYPPGTSTWQFNFKFNLTEDMYAQDSIELLTTSG 120

Query: 121 LQFQKHEEEGIDTLHFAELLMTSGVVLCDNVKWLSFHSGYDFGYMVKLLTDSRLPEEEHE 180
           +QF+KHEEEGI+T +FAELLMTSGVVLC+ VKWLSFHSGYDFGY++K+LT+S LPEEE +
Sbjct: 121 IQFKKHEEEGIETQYFAELLMTSGVVLCEGVKWLSFHSGYDFGYLIKILTNSNLPEEELD 180

Query: 181 FFHILNLFFPSIYDVKYLMKSCKNLKGGLQEVADQLDLQRIGRQHQAGSDSLLTGMAFFR 240
           FF IL LFFP IYDVKYLMKSCKNLKGGLQEVA+QL+L+RIG QHQAGSDSLLTGMAFF+
Sbjct: 181 FFEILRLFFPVIYDVKYLMKSCKNLKGGLQEVAEQLELERIGPQHQAGSDSLLTGMAFFK 240

Query: 241 MKEL 244
           M+E+
Sbjct: 241 MREV 244


>gi|4505611 poly(A)-specific ribonuclease (deadenylation nuclease)
           isoform 1 [Homo sapiens]
          Length = 639

 Score = 35.4 bits (80), Expect = 0.060
 Identities = 35/138 (25%), Positives = 57/138 (41%), Gaps = 14/138 (10%)

Query: 14  EVWASNLEEEMRKIREIVLSYSYIAMDTEFPGVVVRP-IGEFRSSID---YQYQLLRCNV 69
           E+  SN +  + K+ + +    + A+D EF G+   P +    +  D    +YQ L+ + 
Sbjct: 2   EIIRSNFKSNLHKVYQAIEEADFFAIDGEFSGISDGPSVSALTNGFDTPEERYQKLKKHS 61

Query: 70  DLLKIIQLGL-----TFTNEKGEYPSGINTWQFNFKFNLTED----MYSQDSIDLLANSG 120
               + Q GL      +T+ K       N + F   FN +      +    SID LA+ G
Sbjct: 62  MDFLLFQFGLCTFKYDYTDSK-YITKSFNFYVFPKPFNRSSPDVKFVCQSSSIDFLASQG 120

Query: 121 LQFQKHEEEGIDTLHFAE 138
             F K    GI  L+  E
Sbjct: 121 FDFNKVFRNGIPYLNQEE 138


>gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens]
          Length = 4490

 Score = 31.6 bits (70), Expect = 0.86
 Identities = 21/73 (28%), Positives = 36/73 (49%), Gaps = 3/73 (4%)

Query: 56   SSIDYQYQLLRCNVDLLKIIQLGLTFTNEKGEYPSGINTWQFNFKFNLTEDMYSQDS--I 113
            SSI   Y++L  +VD+ KI    L F N   + P G+  WQ         D +S+    +
Sbjct: 1290 SSISGYYEILWGDVDIEKINAELLEFQNRCRKLPKGLKDWQAFLDLKKRIDDFSESCPLL 1349

Query: 114  DLLANSGLQFQKH 126
            +++ N  ++ Q+H
Sbjct: 1350 EMMTNKAMK-QRH 1361


>gi|226371750 terminal uridylyl transferase 1, U6 snRNA-specific
           [Homo sapiens]
          Length = 912

 Score = 31.2 bits (69), Expect = 1.1
 Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 4/63 (6%)

Query: 9   SQVICEVWASNLEEEMRKIREIVLSYSYIAMDTEFPGVVVRPIGEFRSSIDYQYQLLRCN 68
           +Q+I  V    L E  R++R +V++         FPG VV P G   +S D       C+
Sbjct: 199 AQMIKLVGLRELSEAERQLRSLVVALMQEVFTEFFPGCVVHPFGSSINSFDVH----GCD 254

Query: 69  VDL 71
           +DL
Sbjct: 255 LDL 257


>gi|52630326 chromodomain helicase DNA binding protein 3 isoform 1
           [Homo sapiens]
          Length = 2000

 Score = 30.8 bits (68), Expect = 1.5
 Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 11/100 (11%)

Query: 127 EEEGIDTLHFAELLMTSGVVLCDNV-KWLSFHSGYDFGYMVKLLTDSRLPEEEHEFFHIL 185
           ++  + ++ +A L++     L +N  K+    +GY   + + LLT + L     E FH+L
Sbjct: 868 DQAALGSIRWACLVVDEAHRLKNNQSKFFRVLNGYKIDHKL-LLTGTPLQNNLEELFHLL 926

Query: 186 NLFFPSIYDVKYLMKSCKNLKGGLQEVADQLDLQRIGRQH 225
           N   P  ++         NL+G L+E AD     +I + H
Sbjct: 927 NFLTPERFN---------NLEGFLEEFADISKEDQIKKLH 957


>gi|52630322 chromodomain helicase DNA binding protein 3 isoform 2
           [Homo sapiens]
          Length = 1966

 Score = 30.8 bits (68), Expect = 1.5
 Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 11/100 (11%)

Query: 127 EEEGIDTLHFAELLMTSGVVLCDNV-KWLSFHSGYDFGYMVKLLTDSRLPEEEHEFFHIL 185
           ++  + ++ +A L++     L +N  K+    +GY   + + LLT + L     E FH+L
Sbjct: 868 DQAALGSIRWACLVVDEAHRLKNNQSKFFRVLNGYKIDHKL-LLTGTPLQNNLEELFHLL 926

Query: 186 NLFFPSIYDVKYLMKSCKNLKGGLQEVADQLDLQRIGRQH 225
           N   P  ++         NL+G L+E AD     +I + H
Sbjct: 927 NFLTPERFN---------NLEGFLEEFADISKEDQIKKLH 957


>gi|158420731 chromodomain helicase DNA binding protein 3 isoform 3
            [Homo sapiens]
          Length = 2059

 Score = 30.8 bits (68), Expect = 1.5
 Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 11/100 (11%)

Query: 127  EEEGIDTLHFAELLMTSGVVLCDNV-KWLSFHSGYDFGYMVKLLTDSRLPEEEHEFFHIL 185
            ++  + ++ +A L++     L +N  K+    +GY   + + LLT + L     E FH+L
Sbjct: 927  DQAALGSIRWACLVVDEAHRLKNNQSKFFRVLNGYKIDHKL-LLTGTPLQNNLEELFHLL 985

Query: 186  NLFFPSIYDVKYLMKSCKNLKGGLQEVADQLDLQRIGRQH 225
            N   P  ++         NL+G L+E AD     +I + H
Sbjct: 986  NFLTPERFN---------NLEGFLEEFADISKEDQIKKLH 1016


>gi|51599156 chromodomain helicase DNA binding protein 4 [Homo
           sapiens]
          Length = 1912

 Score = 30.0 bits (66), Expect = 2.5
 Identities = 22/74 (29%), Positives = 33/74 (44%), Gaps = 10/74 (13%)

Query: 152 KWLSFHSGYDFGYMVKLLTDSRLPEEEHEFFHILNLFFPSIYDVKYLMKSCKNLKGGLQE 211
           K+    +GY   + + LLT + L     E FH+LN   P  +          NL+G L+E
Sbjct: 884 KFFRVLNGYSLQHKL-LLTGTPLQNNLEELFHLLNFLTPERF---------HNLEGFLEE 933

Query: 212 VADQLDLQRIGRQH 225
            AD     +I + H
Sbjct: 934 FADIAKEDQIKKLH 947


>gi|24308089 chromodomain helicase DNA binding protein 5 [Homo
           sapiens]
          Length = 1954

 Score = 30.0 bits (66), Expect = 2.5
 Identities = 22/74 (29%), Positives = 33/74 (44%), Gaps = 10/74 (13%)

Query: 152 KWLSFHSGYDFGYMVKLLTDSRLPEEEHEFFHILNLFFPSIYDVKYLMKSCKNLKGGLQE 211
           K+    + Y   Y + LLT + L     E FH+LN   P  ++         NL+G L+E
Sbjct: 858 KFFRVLNSYKIDYKL-LLTGTPLQNNLEELFHLLNFLTPERFN---------NLEGFLEE 907

Query: 212 VADQLDLQRIGRQH 225
            AD     +I + H
Sbjct: 908 FADISKEDQIKKLH 921


>gi|158634482 poly (ADP-ribose) polymerase family, member 3 isoform
           b [Homo sapiens]
          Length = 533

 Score = 28.5 bits (62), Expect = 7.3
 Identities = 17/57 (29%), Positives = 26/57 (45%), Gaps = 7/57 (12%)

Query: 49  RPIGEFRSSIDYQYQLLRCNVDLL-------KIIQLGLTFTNEKGEYPSGINTWQFN 98
           + + E    +D  YQLL+C + LL       K+IQ  L  T      P+  + W+ N
Sbjct: 306 KTVEEVPHPLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQTGSNHRCPTLQHIWKVN 362


>gi|158634478 poly (ADP-ribose) polymerase family, member 3 isoform
           a [Homo sapiens]
          Length = 540

 Score = 28.5 bits (62), Expect = 7.3
 Identities = 17/57 (29%), Positives = 26/57 (45%), Gaps = 7/57 (12%)

Query: 49  RPIGEFRSSIDYQYQLLRCNVDLL-------KIIQLGLTFTNEKGEYPSGINTWQFN 98
           + + E    +D  YQLL+C + LL       K+IQ  L  T      P+  + W+ N
Sbjct: 313 KTVEEVPHPLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQTGSNHRCPTLQHIWKVN 369


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.138    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,212,821
Number of Sequences: 37866
Number of extensions: 424130
Number of successful extensions: 896
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 886
Number of HSP's gapped (non-prelim): 17
length of query: 292
length of database: 18,247,518
effective HSP length: 101
effective length of query: 191
effective length of database: 14,423,052
effective search space: 2754802932
effective search space used: 2754802932
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.