Guide to the Human Genome
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Search of human proteins with 122937329

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|122937329 syncollin [Homo sapiens]
         (134 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|122937329 syncollin [Homo sapiens]                                 283   3e-77
gi|197333703 phosphatidylinositol-specific phospholipase C, X do...    31   0.34 
gi|23397570 phosphatidylinositol-specific phospholipase C, X dom...    31   0.34 
gi|139394599 hypermethylated in cancer 2 [Homo sapiens]                30   0.58 
gi|157384998 low density lipoprotein receptor-related protein 4 ...    30   0.76 
gi|169167057 PREDICTED: hypothetical protein [Homo sapiens]            29   0.99 
gi|203097724 cadherin-like 29 [Homo sapiens]                           29   1.3  
gi|88853069 vitronectin precursor [Homo sapiens]                       28   2.2  
gi|9257217 folate receptor 1 precursor [Homo sapiens]                  27   4.9  
gi|9257215 folate receptor 1 precursor [Homo sapiens]                  27   4.9  
gi|9257213 folate receptor 1 precursor [Homo sapiens]                  27   4.9  
gi|9257207 folate receptor 1 precursor [Homo sapiens]                  27   4.9  
gi|9257205 folate receptor 1 precursor [Homo sapiens]                  27   4.9  
gi|4758400 folate receptor 1 precursor [Homo sapiens]                  27   4.9  
gi|41152107 ubiquitin-like 7 [Homo sapiens]                            27   4.9  
gi|14249682 ubiquitin-like 7 [Homo sapiens]                            27   4.9  
gi|126131099 guanine nucleotide exchange factor p532 [Homo sapiens]    27   4.9  
gi|21361910 zinc finger, DHHC domain containing 12 [Homo sapiens]      27   4.9  
gi|4507467 transforming growth factor, beta-induced, 68kDa precu...    27   6.4  
gi|31657094 anillin, actin binding protein [Homo sapiens]              26   8.4  

>gi|122937329 syncollin [Homo sapiens]
          Length = 134

 Score =  283 bits (724), Expect = 3e-77
 Identities = 134/134 (100%), Positives = 134/134 (100%)

Query: 1   MSPLRPLLLALALASVPCAQGACPASADLKHSDGTRTCAKLYDKSDPYYENCCGGAELSL 60
           MSPLRPLLLALALASVPCAQGACPASADLKHSDGTRTCAKLYDKSDPYYENCCGGAELSL
Sbjct: 1   MSPLRPLLLALALASVPCAQGACPASADLKHSDGTRTCAKLYDKSDPYYENCCGGAELSL 60

Query: 61  ESGADLPYLPSNWANTASSLVVAPRCELTVWSRQGKAGKTHKFSAGTYPRLEEYRRGILG 120
           ESGADLPYLPSNWANTASSLVVAPRCELTVWSRQGKAGKTHKFSAGTYPRLEEYRRGILG
Sbjct: 61  ESGADLPYLPSNWANTASSLVVAPRCELTVWSRQGKAGKTHKFSAGTYPRLEEYRRGILG 120

Query: 121 DWSNAISALYCRCS 134
           DWSNAISALYCRCS
Sbjct: 121 DWSNAISALYCRCS 134


>gi|197333703 phosphatidylinositol-specific phospholipase C, X
           domain containing 2 isoform a [Homo sapiens]
          Length = 341

 Score = 30.8 bits (68), Expect = 0.34
 Identities = 18/58 (31%), Positives = 28/58 (48%), Gaps = 1/58 (1%)

Query: 69  LPSNWANTASSLVVAPRCELTVWSRQGKAGKTHKFSAGTYPRLEEYRRGILGDWSNAI 126
           +P+ WANT S   +    E T+ S +   G  H   A   PR++   RG++G   N +
Sbjct: 230 IPAPWANTTSVRKLILFLETTL-SERASRGSFHVSQAILTPRVKTIARGLVGGLKNTL 286


>gi|23397570 phosphatidylinositol-specific phospholipase C, X domain
           containing 2 isoform b [Homo sapiens]
          Length = 304

 Score = 30.8 bits (68), Expect = 0.34
 Identities = 18/58 (31%), Positives = 28/58 (48%), Gaps = 1/58 (1%)

Query: 69  LPSNWANTASSLVVAPRCELTVWSRQGKAGKTHKFSAGTYPRLEEYRRGILGDWSNAI 126
           +P+ WANT S   +    E T+ S +   G  H   A   PR++   RG++G   N +
Sbjct: 230 IPAPWANTTSVRKLILFLETTL-SERASRGSFHVSQAILTPRVKTIARGLVGGLKNTL 286


>gi|139394599 hypermethylated in cancer 2 [Homo sapiens]
          Length = 615

 Score = 30.0 bits (66), Expect = 0.58
 Identities = 18/46 (39%), Positives = 24/46 (52%), Gaps = 1/46 (2%)

Query: 16  VPCAQGACPASADLKHSDGTRTCAKLYDKSDPYYENCCGGAELSLE 61
           +PCA+G  P+S  L     T T  +L+ K +  YE   GGAE   E
Sbjct: 445 IPCAKGF-PSSEQLNAHVETHTEEELFIKEEGAYETGSGGAEEEAE 489


>gi|157384998 low density lipoprotein receptor-related protein 4
           [Homo sapiens]
          Length = 1905

 Score = 29.6 bits (65), Expect = 0.76
 Identities = 17/51 (33%), Positives = 20/51 (39%), Gaps = 2/51 (3%)

Query: 13  LASVPCAQGACPASADLKHSDGTRTCAKLYDKSDPYYENCCGGAELSLESG 63
           L    CA G C    D+ H DG   C    D+SD      C   E   +SG
Sbjct: 193 LEEFQCAYGRC--ILDIYHCDGDDDCGDWSDESDCSSHQPCRSGEFMCDSG 241


>gi|169167057 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 320

 Score = 29.3 bits (64), Expect = 0.99
 Identities = 30/103 (29%), Positives = 40/103 (38%), Gaps = 10/103 (9%)

Query: 14  ASVPCAQGACPASADLKHSDGTRTCAKLYDKSDPYYENCCGGAELSLESGADLPYLPSNW 73
           AS P A  +  A + L+H D  R  A+L   + P+  + C      L +  D P  P +W
Sbjct: 82  ASAPWASLSTRADSGLRHLDRLRKAARLLFVNTPHVRSPC-PIRSPLPAREDPPLSPQHW 140

Query: 74  ANTASSLVVAPR------CELTVW-SRQGKAGKTHKFSAGTYP 109
                 L   PR       E   W  RQ K  +TH   A   P
Sbjct: 141 G--GEILKFPPREKRASSAEPGHWEKRQDKRLETHPCRAPPLP 181


>gi|203097724 cadherin-like 29 [Homo sapiens]
          Length = 788

 Score = 28.9 bits (63), Expect = 1.3
 Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 3/73 (4%)

Query: 13  LASVPCA-QGACPASADLKHSDGTRTCAKLYDKSDPYYENCCGGAELSLESGADLPYLPS 71
           L+ + CA Q A PA   ++  +     A+LY    P  E    GA++S+ S  DLP+ P 
Sbjct: 122 LSHIQCAGQFASPAGEMIQVPETVTPGARLYTLLLPGLE--LHGAQMSIISAQDLPHFPG 179

Query: 72  NWANTASSLVVAP 84
            ++      + AP
Sbjct: 180 PFSINEQGWLQAP 192


>gi|88853069 vitronectin precursor [Homo sapiens]
          Length = 478

 Score = 28.1 bits (61), Expect = 2.2
 Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 6/55 (10%)

Query: 1  MSPLRPLLLALALASVPCA-QGACPASADLKHSDGTRTCAKLY-DKSDPYYENCC 53
          M+PLRPLL+   LA V  A Q +C      + ++G     K   D+   YY++CC
Sbjct: 1  MAPLRPLLILALLAWVALADQESCKG----RCTEGFNVDKKCQCDELCSYYQSCC 51


>gi|9257217 folate receptor 1 precursor [Homo sapiens]
          Length = 257

 Score = 26.9 bits (58), Expect = 4.9
 Identities = 15/49 (30%), Positives = 25/49 (51%), Gaps = 4/49 (8%)

Query: 40 KLYDKSDPYYENCCGGAELSLESGADLPYL-PSNWANTASSLVVAPRCE 87
          KL+++  P+ +N C     S E+  D+ YL   NW +      +AP C+
Sbjct: 52 KLHEQCRPWRKNACCSTNTSQEAHKDVSYLYRFNWNHCGE---MAPACK 97


>gi|9257215 folate receptor 1 precursor [Homo sapiens]
          Length = 257

 Score = 26.9 bits (58), Expect = 4.9
 Identities = 15/49 (30%), Positives = 25/49 (51%), Gaps = 4/49 (8%)

Query: 40 KLYDKSDPYYENCCGGAELSLESGADLPYL-PSNWANTASSLVVAPRCE 87
          KL+++  P+ +N C     S E+  D+ YL   NW +      +AP C+
Sbjct: 52 KLHEQCRPWRKNACCSTNTSQEAHKDVSYLYRFNWNHCGE---MAPACK 97


>gi|9257213 folate receptor 1 precursor [Homo sapiens]
          Length = 257

 Score = 26.9 bits (58), Expect = 4.9
 Identities = 15/49 (30%), Positives = 25/49 (51%), Gaps = 4/49 (8%)

Query: 40 KLYDKSDPYYENCCGGAELSLESGADLPYL-PSNWANTASSLVVAPRCE 87
          KL+++  P+ +N C     S E+  D+ YL   NW +      +AP C+
Sbjct: 52 KLHEQCRPWRKNACCSTNTSQEAHKDVSYLYRFNWNHCGE---MAPACK 97


>gi|9257207 folate receptor 1 precursor [Homo sapiens]
          Length = 257

 Score = 26.9 bits (58), Expect = 4.9
 Identities = 15/49 (30%), Positives = 25/49 (51%), Gaps = 4/49 (8%)

Query: 40 KLYDKSDPYYENCCGGAELSLESGADLPYL-PSNWANTASSLVVAPRCE 87
          KL+++  P+ +N C     S E+  D+ YL   NW +      +AP C+
Sbjct: 52 KLHEQCRPWRKNACCSTNTSQEAHKDVSYLYRFNWNHCGE---MAPACK 97


>gi|9257205 folate receptor 1 precursor [Homo sapiens]
          Length = 257

 Score = 26.9 bits (58), Expect = 4.9
 Identities = 15/49 (30%), Positives = 25/49 (51%), Gaps = 4/49 (8%)

Query: 40 KLYDKSDPYYENCCGGAELSLESGADLPYL-PSNWANTASSLVVAPRCE 87
          KL+++  P+ +N C     S E+  D+ YL   NW +      +AP C+
Sbjct: 52 KLHEQCRPWRKNACCSTNTSQEAHKDVSYLYRFNWNHCGE---MAPACK 97


>gi|4758400 folate receptor 1 precursor [Homo sapiens]
          Length = 257

 Score = 26.9 bits (58), Expect = 4.9
 Identities = 15/49 (30%), Positives = 25/49 (51%), Gaps = 4/49 (8%)

Query: 40 KLYDKSDPYYENCCGGAELSLESGADLPYL-PSNWANTASSLVVAPRCE 87
          KL+++  P+ +N C     S E+  D+ YL   NW +      +AP C+
Sbjct: 52 KLHEQCRPWRKNACCSTNTSQEAHKDVSYLYRFNWNHCGE---MAPACK 97


>gi|41152107 ubiquitin-like 7 [Homo sapiens]
          Length = 380

 Score = 26.9 bits (58), Expect = 4.9
 Identities = 19/67 (28%), Positives = 23/67 (34%)

Query: 7   LLLALALASVPCAQGACPASADLKHSDGTRTCAKLYDKSDPYYENCCGGAELSLESGADL 66
           L  ALALAS P +    P      HS GT   +       P   +    A       +  
Sbjct: 272 LATALALASTPESSSHTPTPGTQGHSSGTSPMSSGVQSGTPITNDLFSQALQHALQASGQ 331

Query: 67  PYLPSNW 73
           P L S W
Sbjct: 332 PSLQSQW 338


>gi|14249682 ubiquitin-like 7 [Homo sapiens]
          Length = 380

 Score = 26.9 bits (58), Expect = 4.9
 Identities = 19/67 (28%), Positives = 23/67 (34%)

Query: 7   LLLALALASVPCAQGACPASADLKHSDGTRTCAKLYDKSDPYYENCCGGAELSLESGADL 66
           L  ALALAS P +    P      HS GT   +       P   +    A       +  
Sbjct: 272 LATALALASTPESSSHTPTPGTQGHSSGTSPMSSGVQSGTPITNDLFSQALQHALQASGQ 331

Query: 67  PYLPSNW 73
           P L S W
Sbjct: 332 PSLQSQW 338


>gi|126131099 guanine nucleotide exchange factor p532 [Homo sapiens]
          Length = 4861

 Score = 26.9 bits (58), Expect = 4.9
 Identities = 23/87 (26%), Positives = 35/87 (40%), Gaps = 9/87 (10%)

Query: 32   SDGTRTCAKLYDKSDPYYENCC-----GGAELSLESGADLPYLPSNWANTASSLVVAPRC 86
            +DGT     +  K     + C      G AE SL S +D  + P +W+ +   L  A   
Sbjct: 3448 NDGTIRVWNVTKKQYSLQQTCVFNRLEGDAEESLGSPSDPSFSPVSWSISGKYLAGALEK 3507

Query: 87   ELTVWSRQGKAG----KTHKFSAGTYP 109
             + +W   G  G    + H  SA  +P
Sbjct: 3508 MVNIWQVNGGKGLVDIQPHWVSALAWP 3534


>gi|21361910 zinc finger, DHHC domain containing 12 [Homo sapiens]
          Length = 267

 Score = 26.9 bits (58), Expect = 4.9
 Identities = 10/25 (40%), Positives = 13/25 (52%)

Query: 30  KHSDGTRTCAKLYDKSDPYYENCCG 54
           +H    R C + YD   P+ ENC G
Sbjct: 111 RHCRECRRCVRRYDHHCPWMENCVG 135


>gi|4507467 transforming growth factor, beta-induced, 68kDa
          precursor [Homo sapiens]
          Length = 683

 Score = 26.6 bits (57), Expect = 6.4
 Identities = 23/61 (37%), Positives = 29/61 (47%), Gaps = 12/61 (19%)

Query: 4  LRPLLLALALASVPCAQGACPASAD----LKHS------DGTRTCA--KLYDKSDPYYEN 51
          +R L LALALA  P A  A PA +     L+HS       G   CA  K+   +  Y+ N
Sbjct: 5  VRLLALALALALGPAATLAGPAKSPYQLVLQHSRLRGRQHGPNVCAVQKVIGTNRKYFTN 64

Query: 52 C 52
          C
Sbjct: 65 C 65


>gi|31657094 anillin, actin binding protein [Homo sapiens]
          Length = 1124

 Score = 26.2 bits (56), Expect = 8.4
 Identities = 15/34 (44%), Positives = 17/34 (50%)

Query: 79  SLVVAPRCELTVWSRQGKAGKTHKFSAGTYPRLE 112
           SLV  PR EL   SR  ++ K  KF     PR E
Sbjct: 624 SLVSTPRLELKDTSRSDESPKPGKFQRTRVPRAE 657


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.132    0.425 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,632,148
Number of Sequences: 37866
Number of extensions: 237120
Number of successful extensions: 513
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 510
Number of HSP's gapped (non-prelim): 20
length of query: 134
length of database: 18,247,518
effective HSP length: 91
effective length of query: 43
effective length of database: 14,801,712
effective search space: 636473616
effective search space used: 636473616
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 56 (26.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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