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Search of human proteins with 122937207
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|122937207 coiled-coil domain containing 61 [Homo sapiens]
(531 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|122937207 coiled-coil domain containing 61 [Homo sapiens] 1058 0.0
gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi... 48 2e-05
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 47 4e-05
gi|119226260 calcium homeostasis endoplasmic reticulum protein [... 47 6e-05
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 46 7e-05
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 46 7e-05
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 46 7e-05
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 46 7e-05
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 46 7e-05
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 46 7e-05
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 46 7e-05
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 46 7e-05
gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens] 45 2e-04
gi|21735550 mitogen-activated protein kinase kinase kinase 10 [H... 44 3e-04
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 44 5e-04
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 44 5e-04
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 43 6e-04
gi|169234647 smoothelin-like 2 isoform 1 [Homo sapiens] 43 6e-04
gi|32484977 angiomotin like 2 [Homo sapiens] 43 6e-04
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 43 8e-04
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 43 8e-04
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 43 8e-04
gi|154090997 coiled-coil domain containing 13 [Homo sapiens] 42 0.001
gi|16262452 cingulin [Homo sapiens] 42 0.001
gi|239754489 PREDICTED: hypothetical protein [Homo sapiens] 42 0.002
gi|239749695 PREDICTED: hypothetical protein XP_002347121 [Homo ... 42 0.002
gi|239743961 PREDICTED: hypothetical protein XP_002344246 [Homo ... 42 0.002
gi|239743069 PREDICTED: hypothetical protein XP_002342750 [Homo ... 42 0.002
gi|239508715 PREDICTED: hypothetical protein [Homo sapiens] 42 0.002
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 41 0.003
>gi|122937207 coiled-coil domain containing 61 [Homo sapiens]
Length = 531
Score = 1058 bits (2737), Expect = 0.0
Identities = 531/531 (100%), Positives = 531/531 (100%)
Query: 1 MRMHTRLSLPGPPHHVGAAYPPAGGNRSENAGSWGGAGASSVEPLARRVASGEATLAMDQ 60
MRMHTRLSLPGPPHHVGAAYPPAGGNRSENAGSWGGAGASSVEPLARRVASGEATLAMDQ
Sbjct: 1 MRMHTRLSLPGPPHHVGAAYPPAGGNRSENAGSWGGAGASSVEPLARRVASGEATLAMDQ 60
Query: 61 PAGLQVDYVFRGVEHAVRVMVSGQVLELEVEDRMTADQWRGEFDAGFIEDLTHKTGNFKQ 120
PAGLQVDYVFRGVEHAVRVMVSGQVLELEVEDRMTADQWRGEFDAGFIEDLTHKTGNFKQ
Sbjct: 61 PAGLQVDYVFRGVEHAVRVMVSGQVLELEVEDRMTADQWRGEFDAGFIEDLTHKTGNFKQ 120
Query: 121 FNIFCHMLESALTQSSESVTLDLLTYTDLESLRNRKMGGRPGSLAPRSAQLNSKRYLILI 180
FNIFCHMLESALTQSSESVTLDLLTYTDLESLRNRKMGGRPGSLAPRSAQLNSKRYLILI
Sbjct: 121 FNIFCHMLESALTQSSESVTLDLLTYTDLESLRNRKMGGRPGSLAPRSAQLNSKRYLILI 180
Query: 181 YSVEFDRIHYPLPLPYQGKPDPVVLQGIIRSLKEELGRLQGLDGQNTRDTRENEIWHLRE 240
YSVEFDRIHYPLPLPYQGKPDPVVLQGIIRSLKEELGRLQGLDGQNTRDTRENEIWHLRE
Sbjct: 181 YSVEFDRIHYPLPLPYQGKPDPVVLQGIIRSLKEELGRLQGLDGQNTRDTRENEIWHLRE 240
Query: 241 QVSRLASEKRELEAQLGRSREEALAGRAARQEAEALRGLVRGLELELRQERGLGHRVAGR 300
QVSRLASEKRELEAQLGRSREEALAGRAARQEAEALRGLVRGLELELRQERGLGHRVAGR
Sbjct: 241 QVSRLASEKRELEAQLGRSREEALAGRAARQEAEALRGLVRGLELELRQERGLGHRVAGR 300
Query: 301 RGQDCRRLAKELEEAKASERSLRARLKTLTSELALYKRGGRGSRGRGRPARPSPSPTGGR 360
RGQDCRRLAKELEEAKASERSLRARLKTLTSELALYKRGGRGSRGRGRPARPSPSPTGGR
Sbjct: 301 RGQDCRRLAKELEEAKASERSLRARLKTLTSELALYKRGGRGSRGRGRPARPSPSPTGGR 360
Query: 361 ALRFDPTAFVKAKERKQREIQMKQQQRNRLGSGGSGDGPSVSWSRQTQPPAALTGRGDAP 420
ALRFDPTAFVKAKERKQREIQMKQQQRNRLGSGGSGDGPSVSWSRQTQPPAALTGRGDAP
Sbjct: 361 ALRFDPTAFVKAKERKQREIQMKQQQRNRLGSGGSGDGPSVSWSRQTQPPAALTGRGDAP 420
Query: 421 NRSRNRSSSVDSFRSRCSSASSCSDLEDFSESLSRGGHRRRGKPPSPTPWSGSNMKSPPV 480
NRSRNRSSSVDSFRSRCSSASSCSDLEDFSESLSRGGHRRRGKPPSPTPWSGSNMKSPPV
Sbjct: 421 NRSRNRSSSVDSFRSRCSSASSCSDLEDFSESLSRGGHRRRGKPPSPTPWSGSNMKSPPV 480
Query: 481 ERSHHQKSLANSGGWVPIKEYSSEHQAADMAEIDARLKALQEYMNRLDMRS 531
ERSHHQKSLANSGGWVPIKEYSSEHQAADMAEIDARLKALQEYMNRLDMRS
Sbjct: 481 ERSHHQKSLANSGGWVPIKEYSSEHQAADMAEIDARLKALQEYMNRLDMRS 531
>gi|133922600 splicing factor, arginine/serine-rich 16 [Homo
sapiens]
Length = 674
Score = 48.1 bits (113), Expect = 2e-05
Identities = 60/219 (27%), Positives = 86/219 (39%), Gaps = 31/219 (14%)
Query: 302 GQDCRRLAKELEEAKASERSLRARLKTLTSELALY--------KRGGRGSRGRGRPARPS 353
G R L K+ EEA+A + + K L E A+Y +R R R RGR P
Sbjct: 233 GDFVRMLRKDKEEAEAIKHA-----KALEEEKAMYSGRRSRRQRREFREKRLRGRKISPP 287
Query: 354 P-----SPTGGRALRFDPTAFVKAKERKQREIQMKQQQRNRLGSGGSGD--------GPS 400
SPT R + +++ R + ++++ + S G D +
Sbjct: 288 SYARRDSPTYDPYKRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAA 347
Query: 401 VSWSRQTQPPAALTGRGDAPNRS---RNRSSSVDSFRSRCSSASSCSDLEDFSESLSRGG 457
S +PPA G AP R+ R RSSS S S ++SS S S S GG
Sbjct: 348 ASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGG 407
Query: 458 HRRRGK--PPSPTPWSGSNMKSPPVERSHHQKSLANSGG 494
+ R G+ WS S +S RS + + GG
Sbjct: 408 YYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGG 446
Score = 35.4 bits (80), Expect = 0.13
Identities = 73/298 (24%), Positives = 105/298 (35%), Gaps = 41/298 (13%)
Query: 248 EKRELEAQLGRSREEALAGRAARQEAEALRGLVRGLELELRQERGLGHRVAGRRGQDCRR 307
EK G S EEA A AA A G+ G Q G A R RR
Sbjct: 324 EKITFITSFGGSDEEAAAAAAAA----AASGVTTGKPPAPPQPGG----PAPGRNASARR 375
Query: 308 LAKELEEAKASERSLRARLKTLTSELAL----YKRGGRG--------SRGRGRPARPSPS 355
+ + ++ R+ +R + +S + Y R GR SR R R R S S
Sbjct: 376 RSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRS 435
Query: 356 PTGGR---------ALRFDPTAFVKAKERKQREIQMKQQQRNRLGSGGSGDGPSVSWSRQ 406
+ GR R+ + + +R + + +R GG G S SR
Sbjct: 436 RSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSS-SRS 494
Query: 407 TQPPAALTGRGDAPNRSRNRSSSVDSFRSRCSSASSCSDLEDFSESLSRGGHRRRGKPPS 466
+ R + RSR+ S S RSR S S E L+R P+
Sbjct: 495 RSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTR---------PA 545
Query: 467 PTPWSGSNMKSPPVERSHHQKSLANSGGWVPIKEYSSEHQAADMAEIDARLKALQEYM 524
+P G +K E + +++ A P ++ Q A + A KA QE M
Sbjct: 546 ASPAVGEKLKK--TEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKM 601
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 47.0 bits (110), Expect = 4e-05
Identities = 67/256 (26%), Positives = 99/256 (38%), Gaps = 36/256 (14%)
Query: 218 RLQGLDGQNTRDTRENEIWHLREQVSRLASEKRELEAQLGRSREEALAGRAARQEAEALR 277
R+Q + + + RE E RE+ +RE E + R RE R +E E +
Sbjct: 389 RVQYTETEPYHNYRERE----RERERENRQRERERERERDRERERRQREREREREHERDK 444
Query: 278 GLVRGLELELRQERGLGHRVAGRRGQDCRRLAKELEEAKASERSLRARLKTLTSELALYK 337
R E R+ + R +D R +E E+ K RS + +
Sbjct: 445 ERQRRKEEWERERAKRDEKDRQHRDRD-REKEREKEKGKPKPRSPQPPSR---------- 493
Query: 338 RGGRGSRGRGRPARPSPSPTGGRALRFD----PTAFVKAKERKQREIQMKQQQRNRLGSG 393
+ P + + TG + R D P K+ ++K + R R +
Sbjct: 494 --------QAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTS 545
Query: 394 GSGDGPSVSWSRQTQPPAALTGRGDAPNRSRNRSSSVDSFRSRCSSASSCSDLEDFSESL 453
S S S SR + ++ +G G + RSR+RSSS S+ SR S SS FS S
Sbjct: 546 ASSASASNS-SRSSSRSSSYSGSGSS--RSRSRSSSYSSYSSRSSRHSS------FSGSR 596
Query: 454 SRGGHRRRGKPPSPTP 469
SR PSPTP
Sbjct: 597 SRSRSFSSSPSPSPTP 612
>gi|119226260 calcium homeostasis endoplasmic reticulum protein
[Homo sapiens]
Length = 916
Score = 46.6 bits (109), Expect = 6e-05
Identities = 41/120 (34%), Positives = 60/120 (50%), Gaps = 5/120 (4%)
Query: 368 AFVKAKERKQREIQMKQQQRNRLGSGGSGDGPSVSWSRQTQPPAALT-GRGDAPNRSRNR 426
A ++A+ RK +E + R+R S G S S SR ++ + + R + +RS +R
Sbjct: 719 AKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSR 778
Query: 427 SSSVDSFRSRCSSASSCSDLEDFSESLSRGGHRRRGKPPSPTPWSGSNMKS---PPVERS 483
S S RSR S + S S S+S S G RRR + SPTP S + + S PP+ S
Sbjct: 779 SRSRSRSRSRSSRSRSRSQSRSRSKSYSPG-RRRRSRSRSPTPPSSAGLGSNSAPPIPDS 837
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 46.2 bits (108), Expect = 7e-05
Identities = 66/318 (20%), Positives = 117/318 (36%), Gaps = 15/318 (4%)
Query: 215 ELGRLQGLDGQNTRDTR--ENEIWHLREQVSRLASEKRELEAQLGRSREEALAGRAARQE 272
EL R +GL R R E EI L+ + A+ K ELE +LGR R A ++++
Sbjct: 1905 ELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQ 1964
Query: 273 AEALRGLVRGLELELRQERGLGHRVAGRRGQDCRRLAKELEEAKASERSLRARLKTLTSE 332
A ELE ++R L RR + R+ K L + + R +A L+ +
Sbjct: 1965 A----------ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERL 2014
Query: 333 LALYKRGGR-GSRGRGRPAR--PSPSPTGGRALRFDPTAFVKAKERKQREIQMKQQQRNR 389
A + R R AR + L+ + A A ++K++E+Q QQ
Sbjct: 2015 KAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQS 2074
Query: 390 LGSGGSGDGPSVSWSRQTQPPAALTGRGDAPNRSRNRSSSVDSFRSRCSSASSCSDLEDF 449
+ G+ + + + A + +A R + +S A + + +
Sbjct: 2075 VLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAA 2134
Query: 450 SESLSRGGHRRRGKPPSPTPWSGSNMKSPPVERSHHQKSLANSGGWVPIKEYSSEHQAAD 509
+E L + + + + ++ E H+K + E
Sbjct: 2135 AEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQ 2194
Query: 510 MAEIDARLKALQEYMNRL 527
+ E D + L E + RL
Sbjct: 2195 LEETDHQKNLLDEELQRL 2212
Score = 37.0 bits (84), Expect = 0.045
Identities = 47/150 (31%), Positives = 65/150 (43%), Gaps = 26/150 (17%)
Query: 212 LKEELGRLQGLDGQNT--RDTRENEIWHLR-------------EQVSRLASE--KRELEA 254
L+EEL RLQ T R E E+ +R E+ SR SE K+ LEA
Sbjct: 1732 LEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEA 1791
Query: 255 QLGRSR---EEALAGRAARQEAEALRGLVRGLELELRQERGLGHRVAGRRGQ---DCRRL 308
+ GR R EEA RA +EA+ R L E + ++R RV + + RL
Sbjct: 1792 EAGRFRELAEEAARLRALAEEAKRQRQLA---EEDAARQRAEAERVLAEKLAAIGEATRL 1848
Query: 309 AKELEEAKASERSLRARLKTLTSELALYKR 338
E E A + + RL+ L + A +R
Sbjct: 1849 KTEAEIALKEKEAENERLRRLAEDEAFQRR 1878
Score = 35.0 bits (79), Expect = 0.17
Identities = 52/204 (25%), Positives = 84/204 (41%), Gaps = 28/204 (13%)
Query: 210 RSLKEELGRL-------------QGLDGQNTRDTRENEIWHLREQVSRLASEKR----EL 252
RS++EEL +L Q + +R E EI +R Q+ ++ EL
Sbjct: 1416 RSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGEL 1475
Query: 253 EAQLGRSREEALAGRAARQEAEALRGLVRGLELELRQ-ERGLGHRV-----AGRRGQDCR 306
+A R+ E R A++EAE LR V+ RQ E L RV A R Q
Sbjct: 1476 QALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRAL 1535
Query: 307 RLAKELE-EAKASERSLR----ARLKTLTSELALYKRGGRGSRGRGRPARPSPSPTGGRA 361
+ +EL +A+ +ER LR R + + L +R R + + R+
Sbjct: 1536 QALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERS 1595
Query: 362 LRFDPTAFVKAKERKQREIQMKQQ 385
L+ + A + +E +R Q + +
Sbjct: 1596 LQEEHVAVAQLREEAERRAQQQAE 1619
Score = 31.2 bits (69), Expect = 2.5
Identities = 31/117 (26%), Positives = 55/117 (47%), Gaps = 9/117 (7%)
Query: 212 LKEELGRLQGLDGQNTRDTRENEIWHLREQVSRLASEKRELEAQLGRSREEALAGRAARQ 271
L+ ELGR++ R + E+ R++ E+R EA+ + A AARQ
Sbjct: 1944 LELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQ 2003
Query: 272 EAEALRGLVRGLELELRQERGLGHRVAGRRGQDCRRLAKELEEA-KASERSLRARLK 327
AL + R L+ ++ + R L R + A++L+ A +A+++ L+A K
Sbjct: 2004 RKAALEEVER-LKAKVEEARRLRERAE-------QESARQLQLAQEAAQKRLQAEEK 2052
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 46.2 bits (108), Expect = 7e-05
Identities = 66/318 (20%), Positives = 117/318 (36%), Gaps = 15/318 (4%)
Query: 215 ELGRLQGLDGQNTRDTR--ENEIWHLREQVSRLASEKRELEAQLGRSREEALAGRAARQE 272
EL R +GL R R E EI L+ + A+ K ELE +LGR R A ++++
Sbjct: 1909 ELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQ 1968
Query: 273 AEALRGLVRGLELELRQERGLGHRVAGRRGQDCRRLAKELEEAKASERSLRARLKTLTSE 332
A ELE ++R L RR + R+ K L + + R +A L+ +
Sbjct: 1969 A----------ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERL 2018
Query: 333 LALYKRGGR-GSRGRGRPAR--PSPSPTGGRALRFDPTAFVKAKERKQREIQMKQQQRNR 389
A + R R AR + L+ + A A ++K++E+Q QQ
Sbjct: 2019 KAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQS 2078
Query: 390 LGSGGSGDGPSVSWSRQTQPPAALTGRGDAPNRSRNRSSSVDSFRSRCSSASSCSDLEDF 449
+ G+ + + + A + +A R + +S A + + +
Sbjct: 2079 VLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAA 2138
Query: 450 SESLSRGGHRRRGKPPSPTPWSGSNMKSPPVERSHHQKSLANSGGWVPIKEYSSEHQAAD 509
+E L + + + + ++ E H+K + E
Sbjct: 2139 AEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQ 2198
Query: 510 MAEIDARLKALQEYMNRL 527
+ E D + L E + RL
Sbjct: 2199 LEETDHQKNLLDEELQRL 2216
Score = 37.0 bits (84), Expect = 0.045
Identities = 47/150 (31%), Positives = 65/150 (43%), Gaps = 26/150 (17%)
Query: 212 LKEELGRLQGLDGQNT--RDTRENEIWHLR-------------EQVSRLASE--KRELEA 254
L+EEL RLQ T R E E+ +R E+ SR SE K+ LEA
Sbjct: 1736 LEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEA 1795
Query: 255 QLGRSR---EEALAGRAARQEAEALRGLVRGLELELRQERGLGHRVAGRRGQ---DCRRL 308
+ GR R EEA RA +EA+ R L E + ++R RV + + RL
Sbjct: 1796 EAGRFRELAEEAARLRALAEEAKRQRQLA---EEDAARQRAEAERVLAEKLAAIGEATRL 1852
Query: 309 AKELEEAKASERSLRARLKTLTSELALYKR 338
E E A + + RL+ L + A +R
Sbjct: 1853 KTEAEIALKEKEAENERLRRLAEDEAFQRR 1882
Score = 35.0 bits (79), Expect = 0.17
Identities = 52/204 (25%), Positives = 84/204 (41%), Gaps = 28/204 (13%)
Query: 210 RSLKEELGRL-------------QGLDGQNTRDTRENEIWHLREQVSRLASEKR----EL 252
RS++EEL +L Q + +R E EI +R Q+ ++ EL
Sbjct: 1420 RSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGEL 1479
Query: 253 EAQLGRSREEALAGRAARQEAEALRGLVRGLELELRQ-ERGLGHRV-----AGRRGQDCR 306
+A R+ E R A++EAE LR V+ RQ E L RV A R Q
Sbjct: 1480 QALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRAL 1539
Query: 307 RLAKELE-EAKASERSLR----ARLKTLTSELALYKRGGRGSRGRGRPARPSPSPTGGRA 361
+ +EL +A+ +ER LR R + + L +R R + + R+
Sbjct: 1540 QALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERS 1599
Query: 362 LRFDPTAFVKAKERKQREIQMKQQ 385
L+ + A + +E +R Q + +
Sbjct: 1600 LQEEHVAVAQLREEAERRAQQQAE 1623
Score = 31.2 bits (69), Expect = 2.5
Identities = 31/117 (26%), Positives = 55/117 (47%), Gaps = 9/117 (7%)
Query: 212 LKEELGRLQGLDGQNTRDTRENEIWHLREQVSRLASEKRELEAQLGRSREEALAGRAARQ 271
L+ ELGR++ R + E+ R++ E+R EA+ + A AARQ
Sbjct: 1948 LELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQ 2007
Query: 272 EAEALRGLVRGLELELRQERGLGHRVAGRRGQDCRRLAKELEEA-KASERSLRARLK 327
AL + R L+ ++ + R L R + A++L+ A +A+++ L+A K
Sbjct: 2008 RKAALEEVER-LKAKVEEARRLRERAE-------QESARQLQLAQEAAQKRLQAEEK 2056
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 46.2 bits (108), Expect = 7e-05
Identities = 66/318 (20%), Positives = 117/318 (36%), Gaps = 15/318 (4%)
Query: 215 ELGRLQGLDGQNTRDTR--ENEIWHLREQVSRLASEKRELEAQLGRSREEALAGRAARQE 272
EL R +GL R R E EI L+ + A+ K ELE +LGR R A ++++
Sbjct: 1905 ELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQ 1964
Query: 273 AEALRGLVRGLELELRQERGLGHRVAGRRGQDCRRLAKELEEAKASERSLRARLKTLTSE 332
A ELE ++R L RR + R+ K L + + R +A L+ +
Sbjct: 1965 A----------ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERL 2014
Query: 333 LALYKRGGR-GSRGRGRPAR--PSPSPTGGRALRFDPTAFVKAKERKQREIQMKQQQRNR 389
A + R R AR + L+ + A A ++K++E+Q QQ
Sbjct: 2015 KAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQS 2074
Query: 390 LGSGGSGDGPSVSWSRQTQPPAALTGRGDAPNRSRNRSSSVDSFRSRCSSASSCSDLEDF 449
+ G+ + + + A + +A R + +S A + + +
Sbjct: 2075 VLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAA 2134
Query: 450 SESLSRGGHRRRGKPPSPTPWSGSNMKSPPVERSHHQKSLANSGGWVPIKEYSSEHQAAD 509
+E L + + + + ++ E H+K + E
Sbjct: 2135 AEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQ 2194
Query: 510 MAEIDARLKALQEYMNRL 527
+ E D + L E + RL
Sbjct: 2195 LEETDHQKNLLDEELQRL 2212
Score = 37.0 bits (84), Expect = 0.045
Identities = 47/150 (31%), Positives = 65/150 (43%), Gaps = 26/150 (17%)
Query: 212 LKEELGRLQGLDGQNT--RDTRENEIWHLR-------------EQVSRLASE--KRELEA 254
L+EEL RLQ T R E E+ +R E+ SR SE K+ LEA
Sbjct: 1732 LEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEA 1791
Query: 255 QLGRSR---EEALAGRAARQEAEALRGLVRGLELELRQERGLGHRVAGRRGQ---DCRRL 308
+ GR R EEA RA +EA+ R L E + ++R RV + + RL
Sbjct: 1792 EAGRFRELAEEAARLRALAEEAKRQRQLA---EEDAARQRAEAERVLAEKLAAIGEATRL 1848
Query: 309 AKELEEAKASERSLRARLKTLTSELALYKR 338
E E A + + RL+ L + A +R
Sbjct: 1849 KTEAEIALKEKEAENERLRRLAEDEAFQRR 1878
Score = 35.0 bits (79), Expect = 0.17
Identities = 52/204 (25%), Positives = 84/204 (41%), Gaps = 28/204 (13%)
Query: 210 RSLKEELGRL-------------QGLDGQNTRDTRENEIWHLREQVSRLASEKR----EL 252
RS++EEL +L Q + +R E EI +R Q+ ++ EL
Sbjct: 1416 RSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGEL 1475
Query: 253 EAQLGRSREEALAGRAARQEAEALRGLVRGLELELRQ-ERGLGHRV-----AGRRGQDCR 306
+A R+ E R A++EAE LR V+ RQ E L RV A R Q
Sbjct: 1476 QALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRAL 1535
Query: 307 RLAKELE-EAKASERSLR----ARLKTLTSELALYKRGGRGSRGRGRPARPSPSPTGGRA 361
+ +EL +A+ +ER LR R + + L +R R + + R+
Sbjct: 1536 QALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERS 1595
Query: 362 LRFDPTAFVKAKERKQREIQMKQQ 385
L+ + A + +E +R Q + +
Sbjct: 1596 LQEEHVAVAQLREEAERRAQQQAE 1619
Score = 31.2 bits (69), Expect = 2.5
Identities = 31/117 (26%), Positives = 55/117 (47%), Gaps = 9/117 (7%)
Query: 212 LKEELGRLQGLDGQNTRDTRENEIWHLREQVSRLASEKRELEAQLGRSREEALAGRAARQ 271
L+ ELGR++ R + E+ R++ E+R EA+ + A AARQ
Sbjct: 1944 LELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQ 2003
Query: 272 EAEALRGLVRGLELELRQERGLGHRVAGRRGQDCRRLAKELEEA-KASERSLRARLK 327
AL + R L+ ++ + R L R + A++L+ A +A+++ L+A K
Sbjct: 2004 RKAALEEVER-LKAKVEEARRLRERAE-------QESARQLQLAQEAAQKRLQAEEK 2052
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 46.2 bits (108), Expect = 7e-05
Identities = 66/318 (20%), Positives = 117/318 (36%), Gaps = 15/318 (4%)
Query: 215 ELGRLQGLDGQNTRDTR--ENEIWHLREQVSRLASEKRELEAQLGRSREEALAGRAARQE 272
EL R +GL R R E EI L+ + A+ K ELE +LGR R A ++++
Sbjct: 1873 ELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQ 1932
Query: 273 AEALRGLVRGLELELRQERGLGHRVAGRRGQDCRRLAKELEEAKASERSLRARLKTLTSE 332
A ELE ++R L RR + R+ K L + + R +A L+ +
Sbjct: 1933 A----------ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERL 1982
Query: 333 LALYKRGGR-GSRGRGRPAR--PSPSPTGGRALRFDPTAFVKAKERKQREIQMKQQQRNR 389
A + R R AR + L+ + A A ++K++E+Q QQ
Sbjct: 1983 KAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQS 2042
Query: 390 LGSGGSGDGPSVSWSRQTQPPAALTGRGDAPNRSRNRSSSVDSFRSRCSSASSCSDLEDF 449
+ G+ + + + A + +A R + +S A + + +
Sbjct: 2043 VLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAA 2102
Query: 450 SESLSRGGHRRRGKPPSPTPWSGSNMKSPPVERSHHQKSLANSGGWVPIKEYSSEHQAAD 509
+E L + + + + ++ E H+K + E
Sbjct: 2103 AEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQ 2162
Query: 510 MAEIDARLKALQEYMNRL 527
+ E D + L E + RL
Sbjct: 2163 LEETDHQKNLLDEELQRL 2180
Score = 37.0 bits (84), Expect = 0.045
Identities = 47/150 (31%), Positives = 65/150 (43%), Gaps = 26/150 (17%)
Query: 212 LKEELGRLQGLDGQNT--RDTRENEIWHLR-------------EQVSRLASE--KRELEA 254
L+EEL RLQ T R E E+ +R E+ SR SE K+ LEA
Sbjct: 1700 LEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEA 1759
Query: 255 QLGRSR---EEALAGRAARQEAEALRGLVRGLELELRQERGLGHRVAGRRGQ---DCRRL 308
+ GR R EEA RA +EA+ R L E + ++R RV + + RL
Sbjct: 1760 EAGRFRELAEEAARLRALAEEAKRQRQLA---EEDAARQRAEAERVLAEKLAAIGEATRL 1816
Query: 309 AKELEEAKASERSLRARLKTLTSELALYKR 338
E E A + + RL+ L + A +R
Sbjct: 1817 KTEAEIALKEKEAENERLRRLAEDEAFQRR 1846
Score = 35.0 bits (79), Expect = 0.17
Identities = 52/204 (25%), Positives = 84/204 (41%), Gaps = 28/204 (13%)
Query: 210 RSLKEELGRL-------------QGLDGQNTRDTRENEIWHLREQVSRLASEKR----EL 252
RS++EEL +L Q + +R E EI +R Q+ ++ EL
Sbjct: 1384 RSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGEL 1443
Query: 253 EAQLGRSREEALAGRAARQEAEALRGLVRGLELELRQ-ERGLGHRV-----AGRRGQDCR 306
+A R+ E R A++EAE LR V+ RQ E L RV A R Q
Sbjct: 1444 QALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRAL 1503
Query: 307 RLAKELE-EAKASERSLR----ARLKTLTSELALYKRGGRGSRGRGRPARPSPSPTGGRA 361
+ +EL +A+ +ER LR R + + L +R R + + R+
Sbjct: 1504 QALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERS 1563
Query: 362 LRFDPTAFVKAKERKQREIQMKQQ 385
L+ + A + +E +R Q + +
Sbjct: 1564 LQEEHVAVAQLREEAERRAQQQAE 1587
Score = 31.2 bits (69), Expect = 2.5
Identities = 31/117 (26%), Positives = 55/117 (47%), Gaps = 9/117 (7%)
Query: 212 LKEELGRLQGLDGQNTRDTRENEIWHLREQVSRLASEKRELEAQLGRSREEALAGRAARQ 271
L+ ELGR++ R + E+ R++ E+R EA+ + A AARQ
Sbjct: 1912 LELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQ 1971
Query: 272 EAEALRGLVRGLELELRQERGLGHRVAGRRGQDCRRLAKELEEA-KASERSLRARLK 327
AL + R L+ ++ + R L R + A++L+ A +A+++ L+A K
Sbjct: 1972 RKAALEEVER-LKAKVEEARRLRERAE-------QESARQLQLAQEAAQKRLQAEEK 2020
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 46.2 bits (108), Expect = 7e-05
Identities = 66/318 (20%), Positives = 117/318 (36%), Gaps = 15/318 (4%)
Query: 215 ELGRLQGLDGQNTRDTR--ENEIWHLREQVSRLASEKRELEAQLGRSREEALAGRAARQE 272
EL R +GL R R E EI L+ + A+ K ELE +LGR R A ++++
Sbjct: 2042 ELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQ 2101
Query: 273 AEALRGLVRGLELELRQERGLGHRVAGRRGQDCRRLAKELEEAKASERSLRARLKTLTSE 332
A ELE ++R L RR + R+ K L + + R +A L+ +
Sbjct: 2102 A----------ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERL 2151
Query: 333 LALYKRGGR-GSRGRGRPAR--PSPSPTGGRALRFDPTAFVKAKERKQREIQMKQQQRNR 389
A + R R AR + L+ + A A ++K++E+Q QQ
Sbjct: 2152 KAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQS 2211
Query: 390 LGSGGSGDGPSVSWSRQTQPPAALTGRGDAPNRSRNRSSSVDSFRSRCSSASSCSDLEDF 449
+ G+ + + + A + +A R + +S A + + +
Sbjct: 2212 VLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAA 2271
Query: 450 SESLSRGGHRRRGKPPSPTPWSGSNMKSPPVERSHHQKSLANSGGWVPIKEYSSEHQAAD 509
+E L + + + + ++ E H+K + E
Sbjct: 2272 AEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQ 2331
Query: 510 MAEIDARLKALQEYMNRL 527
+ E D + L E + RL
Sbjct: 2332 LEETDHQKNLLDEELQRL 2349
Score = 37.0 bits (84), Expect = 0.045
Identities = 47/150 (31%), Positives = 65/150 (43%), Gaps = 26/150 (17%)
Query: 212 LKEELGRLQGLDGQNT--RDTRENEIWHLR-------------EQVSRLASE--KRELEA 254
L+EEL RLQ T R E E+ +R E+ SR SE K+ LEA
Sbjct: 1869 LEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEA 1928
Query: 255 QLGRSR---EEALAGRAARQEAEALRGLVRGLELELRQERGLGHRVAGRRGQ---DCRRL 308
+ GR R EEA RA +EA+ R L E + ++R RV + + RL
Sbjct: 1929 EAGRFRELAEEAARLRALAEEAKRQRQLA---EEDAARQRAEAERVLAEKLAAIGEATRL 1985
Query: 309 AKELEEAKASERSLRARLKTLTSELALYKR 338
E E A + + RL+ L + A +R
Sbjct: 1986 KTEAEIALKEKEAENERLRRLAEDEAFQRR 2015
Score = 35.0 bits (79), Expect = 0.17
Identities = 52/204 (25%), Positives = 84/204 (41%), Gaps = 28/204 (13%)
Query: 210 RSLKEELGRL-------------QGLDGQNTRDTRENEIWHLREQVSRLASEKR----EL 252
RS++EEL +L Q + +R E EI +R Q+ ++ EL
Sbjct: 1553 RSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGEL 1612
Query: 253 EAQLGRSREEALAGRAARQEAEALRGLVRGLELELRQ-ERGLGHRV-----AGRRGQDCR 306
+A R+ E R A++EAE LR V+ RQ E L RV A R Q
Sbjct: 1613 QALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRAL 1672
Query: 307 RLAKELE-EAKASERSLR----ARLKTLTSELALYKRGGRGSRGRGRPARPSPSPTGGRA 361
+ +EL +A+ +ER LR R + + L +R R + + R+
Sbjct: 1673 QALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERS 1732
Query: 362 LRFDPTAFVKAKERKQREIQMKQQ 385
L+ + A + +E +R Q + +
Sbjct: 1733 LQEEHVAVAQLREEAERRAQQQAE 1756
Score = 31.2 bits (69), Expect = 2.5
Identities = 31/117 (26%), Positives = 55/117 (47%), Gaps = 9/117 (7%)
Query: 212 LKEELGRLQGLDGQNTRDTRENEIWHLREQVSRLASEKRELEAQLGRSREEALAGRAARQ 271
L+ ELGR++ R + E+ R++ E+R EA+ + A AARQ
Sbjct: 2081 LELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQ 2140
Query: 272 EAEALRGLVRGLELELRQERGLGHRVAGRRGQDCRRLAKELEEA-KASERSLRARLK 327
AL + R L+ ++ + R L R + A++L+ A +A+++ L+A K
Sbjct: 2141 RKAALEEVER-LKAKVEEARRLRERAE-------QESARQLQLAQEAAQKRLQAEEK 2189
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 46.2 bits (108), Expect = 7e-05
Identities = 66/318 (20%), Positives = 117/318 (36%), Gaps = 15/318 (4%)
Query: 215 ELGRLQGLDGQNTRDTR--ENEIWHLREQVSRLASEKRELEAQLGRSREEALAGRAARQE 272
EL R +GL R R E EI L+ + A+ K ELE +LGR R A ++++
Sbjct: 1883 ELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQ 1942
Query: 273 AEALRGLVRGLELELRQERGLGHRVAGRRGQDCRRLAKELEEAKASERSLRARLKTLTSE 332
A ELE ++R L RR + R+ K L + + R +A L+ +
Sbjct: 1943 A----------ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERL 1992
Query: 333 LALYKRGGR-GSRGRGRPAR--PSPSPTGGRALRFDPTAFVKAKERKQREIQMKQQQRNR 389
A + R R AR + L+ + A A ++K++E+Q QQ
Sbjct: 1993 KAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQS 2052
Query: 390 LGSGGSGDGPSVSWSRQTQPPAALTGRGDAPNRSRNRSSSVDSFRSRCSSASSCSDLEDF 449
+ G+ + + + A + +A R + +S A + + +
Sbjct: 2053 VLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAA 2112
Query: 450 SESLSRGGHRRRGKPPSPTPWSGSNMKSPPVERSHHQKSLANSGGWVPIKEYSSEHQAAD 509
+E L + + + + ++ E H+K + E
Sbjct: 2113 AEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQ 2172
Query: 510 MAEIDARLKALQEYMNRL 527
+ E D + L E + RL
Sbjct: 2173 LEETDHQKNLLDEELQRL 2190
Score = 37.0 bits (84), Expect = 0.045
Identities = 47/150 (31%), Positives = 65/150 (43%), Gaps = 26/150 (17%)
Query: 212 LKEELGRLQGLDGQNT--RDTRENEIWHLR-------------EQVSRLASE--KRELEA 254
L+EEL RLQ T R E E+ +R E+ SR SE K+ LEA
Sbjct: 1710 LEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEA 1769
Query: 255 QLGRSR---EEALAGRAARQEAEALRGLVRGLELELRQERGLGHRVAGRRGQ---DCRRL 308
+ GR R EEA RA +EA+ R L E + ++R RV + + RL
Sbjct: 1770 EAGRFRELAEEAARLRALAEEAKRQRQLA---EEDAARQRAEAERVLAEKLAAIGEATRL 1826
Query: 309 AKELEEAKASERSLRARLKTLTSELALYKR 338
E E A + + RL+ L + A +R
Sbjct: 1827 KTEAEIALKEKEAENERLRRLAEDEAFQRR 1856
Score = 35.0 bits (79), Expect = 0.17
Identities = 52/204 (25%), Positives = 84/204 (41%), Gaps = 28/204 (13%)
Query: 210 RSLKEELGRL-------------QGLDGQNTRDTRENEIWHLREQVSRLASEKR----EL 252
RS++EEL +L Q + +R E EI +R Q+ ++ EL
Sbjct: 1394 RSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGEL 1453
Query: 253 EAQLGRSREEALAGRAARQEAEALRGLVRGLELELRQ-ERGLGHRV-----AGRRGQDCR 306
+A R+ E R A++EAE LR V+ RQ E L RV A R Q
Sbjct: 1454 QALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRAL 1513
Query: 307 RLAKELE-EAKASERSLR----ARLKTLTSELALYKRGGRGSRGRGRPARPSPSPTGGRA 361
+ +EL +A+ +ER LR R + + L +R R + + R+
Sbjct: 1514 QALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERS 1573
Query: 362 LRFDPTAFVKAKERKQREIQMKQQ 385
L+ + A + +E +R Q + +
Sbjct: 1574 LQEEHVAVAQLREEAERRAQQQAE 1597
Score = 31.2 bits (69), Expect = 2.5
Identities = 31/117 (26%), Positives = 55/117 (47%), Gaps = 9/117 (7%)
Query: 212 LKEELGRLQGLDGQNTRDTRENEIWHLREQVSRLASEKRELEAQLGRSREEALAGRAARQ 271
L+ ELGR++ R + E+ R++ E+R EA+ + A AARQ
Sbjct: 1922 LELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQ 1981
Query: 272 EAEALRGLVRGLELELRQERGLGHRVAGRRGQDCRRLAKELEEA-KASERSLRARLK 327
AL + R L+ ++ + R L R + A++L+ A +A+++ L+A K
Sbjct: 1982 RKAALEEVER-LKAKVEEARRLRERAE-------QESARQLQLAQEAAQKRLQAEEK 2030
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 46.2 bits (108), Expect = 7e-05
Identities = 66/318 (20%), Positives = 117/318 (36%), Gaps = 15/318 (4%)
Query: 215 ELGRLQGLDGQNTRDTR--ENEIWHLREQVSRLASEKRELEAQLGRSREEALAGRAARQE 272
EL R +GL R R E EI L+ + A+ K ELE +LGR R A ++++
Sbjct: 1891 ELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQ 1950
Query: 273 AEALRGLVRGLELELRQERGLGHRVAGRRGQDCRRLAKELEEAKASERSLRARLKTLTSE 332
A ELE ++R L RR + R+ K L + + R +A L+ +
Sbjct: 1951 A----------ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERL 2000
Query: 333 LALYKRGGR-GSRGRGRPAR--PSPSPTGGRALRFDPTAFVKAKERKQREIQMKQQQRNR 389
A + R R AR + L+ + A A ++K++E+Q QQ
Sbjct: 2001 KAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQS 2060
Query: 390 LGSGGSGDGPSVSWSRQTQPPAALTGRGDAPNRSRNRSSSVDSFRSRCSSASSCSDLEDF 449
+ G+ + + + A + +A R + +S A + + +
Sbjct: 2061 VLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAA 2120
Query: 450 SESLSRGGHRRRGKPPSPTPWSGSNMKSPPVERSHHQKSLANSGGWVPIKEYSSEHQAAD 509
+E L + + + + ++ E H+K + E
Sbjct: 2121 AEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQ 2180
Query: 510 MAEIDARLKALQEYMNRL 527
+ E D + L E + RL
Sbjct: 2181 LEETDHQKNLLDEELQRL 2198
Score = 37.0 bits (84), Expect = 0.045
Identities = 47/150 (31%), Positives = 65/150 (43%), Gaps = 26/150 (17%)
Query: 212 LKEELGRLQGLDGQNT--RDTRENEIWHLR-------------EQVSRLASE--KRELEA 254
L+EEL RLQ T R E E+ +R E+ SR SE K+ LEA
Sbjct: 1718 LEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEA 1777
Query: 255 QLGRSR---EEALAGRAARQEAEALRGLVRGLELELRQERGLGHRVAGRRGQ---DCRRL 308
+ GR R EEA RA +EA+ R L E + ++R RV + + RL
Sbjct: 1778 EAGRFRELAEEAARLRALAEEAKRQRQLA---EEDAARQRAEAERVLAEKLAAIGEATRL 1834
Query: 309 AKELEEAKASERSLRARLKTLTSELALYKR 338
E E A + + RL+ L + A +R
Sbjct: 1835 KTEAEIALKEKEAENERLRRLAEDEAFQRR 1864
Score = 35.0 bits (79), Expect = 0.17
Identities = 52/204 (25%), Positives = 84/204 (41%), Gaps = 28/204 (13%)
Query: 210 RSLKEELGRL-------------QGLDGQNTRDTRENEIWHLREQVSRLASEKR----EL 252
RS++EEL +L Q + +R E EI +R Q+ ++ EL
Sbjct: 1402 RSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGEL 1461
Query: 253 EAQLGRSREEALAGRAARQEAEALRGLVRGLELELRQ-ERGLGHRV-----AGRRGQDCR 306
+A R+ E R A++EAE LR V+ RQ E L RV A R Q
Sbjct: 1462 QALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRAL 1521
Query: 307 RLAKELE-EAKASERSLR----ARLKTLTSELALYKRGGRGSRGRGRPARPSPSPTGGRA 361
+ +EL +A+ +ER LR R + + L +R R + + R+
Sbjct: 1522 QALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERS 1581
Query: 362 LRFDPTAFVKAKERKQREIQMKQQ 385
L+ + A + +E +R Q + +
Sbjct: 1582 LQEEHVAVAQLREEAERRAQQQAE 1605
Score = 31.2 bits (69), Expect = 2.5
Identities = 31/117 (26%), Positives = 55/117 (47%), Gaps = 9/117 (7%)
Query: 212 LKEELGRLQGLDGQNTRDTRENEIWHLREQVSRLASEKRELEAQLGRSREEALAGRAARQ 271
L+ ELGR++ R + E+ R++ E+R EA+ + A AARQ
Sbjct: 1930 LELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQ 1989
Query: 272 EAEALRGLVRGLELELRQERGLGHRVAGRRGQDCRRLAKELEEA-KASERSLRARLK 327
AL + R L+ ++ + R L R + A++L+ A +A+++ L+A K
Sbjct: 1990 RKAALEEVER-LKAKVEEARRLRERAE-------QESARQLQLAQEAAQKRLQAEEK 2038
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 46.2 bits (108), Expect = 7e-05
Identities = 66/318 (20%), Positives = 117/318 (36%), Gaps = 15/318 (4%)
Query: 215 ELGRLQGLDGQNTRDTR--ENEIWHLREQVSRLASEKRELEAQLGRSREEALAGRAARQE 272
EL R +GL R R E EI L+ + A+ K ELE +LGR R A ++++
Sbjct: 1932 ELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQ 1991
Query: 273 AEALRGLVRGLELELRQERGLGHRVAGRRGQDCRRLAKELEEAKASERSLRARLKTLTSE 332
A ELE ++R L RR + R+ K L + + R +A L+ +
Sbjct: 1992 A----------ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERL 2041
Query: 333 LALYKRGGR-GSRGRGRPAR--PSPSPTGGRALRFDPTAFVKAKERKQREIQMKQQQRNR 389
A + R R AR + L+ + A A ++K++E+Q QQ
Sbjct: 2042 KAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQS 2101
Query: 390 LGSGGSGDGPSVSWSRQTQPPAALTGRGDAPNRSRNRSSSVDSFRSRCSSASSCSDLEDF 449
+ G+ + + + A + +A R + +S A + + +
Sbjct: 2102 VLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAA 2161
Query: 450 SESLSRGGHRRRGKPPSPTPWSGSNMKSPPVERSHHQKSLANSGGWVPIKEYSSEHQAAD 509
+E L + + + + ++ E H+K + E
Sbjct: 2162 AEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQ 2221
Query: 510 MAEIDARLKALQEYMNRL 527
+ E D + L E + RL
Sbjct: 2222 LEETDHQKNLLDEELQRL 2239
Score = 37.0 bits (84), Expect = 0.045
Identities = 47/150 (31%), Positives = 65/150 (43%), Gaps = 26/150 (17%)
Query: 212 LKEELGRLQGLDGQNT--RDTRENEIWHLR-------------EQVSRLASE--KRELEA 254
L+EEL RLQ T R E E+ +R E+ SR SE K+ LEA
Sbjct: 1759 LEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEA 1818
Query: 255 QLGRSR---EEALAGRAARQEAEALRGLVRGLELELRQERGLGHRVAGRRGQ---DCRRL 308
+ GR R EEA RA +EA+ R L E + ++R RV + + RL
Sbjct: 1819 EAGRFRELAEEAARLRALAEEAKRQRQLA---EEDAARQRAEAERVLAEKLAAIGEATRL 1875
Query: 309 AKELEEAKASERSLRARLKTLTSELALYKR 338
E E A + + RL+ L + A +R
Sbjct: 1876 KTEAEIALKEKEAENERLRRLAEDEAFQRR 1905
Score = 35.0 bits (79), Expect = 0.17
Identities = 52/204 (25%), Positives = 84/204 (41%), Gaps = 28/204 (13%)
Query: 210 RSLKEELGRL-------------QGLDGQNTRDTRENEIWHLREQVSRLASEKR----EL 252
RS++EEL +L Q + +R E EI +R Q+ ++ EL
Sbjct: 1443 RSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGEL 1502
Query: 253 EAQLGRSREEALAGRAARQEAEALRGLVRGLELELRQ-ERGLGHRV-----AGRRGQDCR 306
+A R+ E R A++EAE LR V+ RQ E L RV A R Q
Sbjct: 1503 QALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRAL 1562
Query: 307 RLAKELE-EAKASERSLR----ARLKTLTSELALYKRGGRGSRGRGRPARPSPSPTGGRA 361
+ +EL +A+ +ER LR R + + L +R R + + R+
Sbjct: 1563 QALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERS 1622
Query: 362 LRFDPTAFVKAKERKQREIQMKQQ 385
L+ + A + +E +R Q + +
Sbjct: 1623 LQEEHVAVAQLREEAERRAQQQAE 1646
Score = 31.2 bits (69), Expect = 2.5
Identities = 31/117 (26%), Positives = 55/117 (47%), Gaps = 9/117 (7%)
Query: 212 LKEELGRLQGLDGQNTRDTRENEIWHLREQVSRLASEKRELEAQLGRSREEALAGRAARQ 271
L+ ELGR++ R + E+ R++ E+R EA+ + A AARQ
Sbjct: 1971 LELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQ 2030
Query: 272 EAEALRGLVRGLELELRQERGLGHRVAGRRGQDCRRLAKELEEA-KASERSLRARLK 327
AL + R L+ ++ + R L R + A++L+ A +A+++ L+A K
Sbjct: 2031 RKAALEEVER-LKAKVEEARRLRERAE-------QESARQLQLAQEAAQKRLQAEEK 2079
>gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]
Length = 344
Score = 45.1 bits (105), Expect = 2e-04
Identities = 50/188 (26%), Positives = 80/188 (42%), Gaps = 23/188 (12%)
Query: 300 RRGQDCRRLAKELEEAKASERSLRA-RLKTLTSELALYKRGGRGSRGRGRPARPSPSPTG 358
R D +R +L+ + + R++R K TS ++R GSR R R R S S +
Sbjct: 154 RSYSDMKRALDKLDGTEINGRNIRLIEDKPRTS----HRRSYSGSRSRSRSRRRSRSRSR 209
Query: 359 GRALRFDPTAFVKAKERKQREIQMKQQQRNRLGSGGSGDGPSVSWSRQTQPPAALTGRGD 418
++ + R I + R+R S G S S R+++ + + D
Sbjct: 210 ------------RSSRSRSRSIS---KSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSD 254
Query: 419 APNRSRNRSSSVDSF---RSRCSSASSCSDLEDFSESLSRGGHRRRGKPPSPTPWSGSNM 475
+ S +RS S D + RSR S S + + +S SR + R P P P S +
Sbjct: 255 RGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARS 314
Query: 476 KSPPVERS 483
SPP +R+
Sbjct: 315 VSPPPKRA 322
Score = 39.3 bits (90), Expect = 0.009
Identities = 55/228 (24%), Positives = 93/228 (40%), Gaps = 24/228 (10%)
Query: 236 WHLREQVSRLASEKRELEAQLGRSREEALAGRAARQEAEALRGL----VRGLELELRQER 291
W + R A E +A R+ E + R+ AL L + G + L +++
Sbjct: 123 WQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDK 182
Query: 292 GLGHRVAGRRGQDCRRLAKELEEAKASERSLRARLKTLTSELALYKRGGRG---SRGRGR 348
G R ++ ++ S RS R+R ++++ + + +G SR +GR
Sbjct: 183 PRTSHRRSYSGSRSRSRSRRRSRSR-SRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGR 241
Query: 349 PARPSPSPTGGRALRFDPTAFVKAKERKQREIQMKQQQRNRLGS---GGSGDGPSVSWSR 405
+R S S + ++ D + ++ R + E + K + R+R S G GD S S SR
Sbjct: 242 KSR-SKSKSKPKS---DRGSHSHSRSRSKDEYE-KSRSRSRSRSPKENGKGDIKSKSRSR 296
Query: 406 QTQ--------PPAALTGRGDAPNRSRNRSSSVDSFRSRCSSASSCSD 445
PP+ P R+ +RS S +SR S SS D
Sbjct: 297 SQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSRD 344
Score = 29.6 bits (65), Expect = 7.2
Identities = 27/72 (37%), Positives = 31/72 (43%), Gaps = 3/72 (4%)
Query: 416 RGDAPNRSRNRSSSVDSFRSRCSSAS---SCSDLEDFSESLSRGGHRRRGKPPSPTPWSG 472
R + +RSR+RS RSR SS S S S S S S+G R R K S
Sbjct: 189 RSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSK 248
Query: 473 SNMKSPPVERSH 484
S KS SH
Sbjct: 249 SKPKSDRGSHSH 260
>gi|21735550 mitogen-activated protein kinase kinase kinase 10 [Homo
sapiens]
Length = 954
Score = 44.3 bits (103), Expect = 3e-04
Identities = 70/243 (28%), Positives = 97/243 (39%), Gaps = 37/243 (15%)
Query: 230 TRENEIWHLREQVSRLASEKRELEAQLGRSREEALAGRAARQEAEALRGLVRGLELELRQ 289
T+E E+ E++ R A E+R E QL R RE+ LA R E + + + L +L Q
Sbjct: 393 TKEKELRSREEELLRAAQEQRFQEEQL-RRREQELAER----EMDIVERELHLLMCQLSQ 447
Query: 290 ERGLGHRVAGRRGQDCRRLAKELEEAKASERSLRARLK---TLTSELALYKRGGRGSRGR 346
E+ RV R+G R +L E S SL + + T+ + L KR +GS G
Sbjct: 448 EK---PRVRKRKGNFKRSRLLKLREG-GSHISLPSGFEHKITVQASPTLDKR--KGSDGA 501
Query: 347 GRPARPSPSPTGGRALRFDPTAFVKAKERKQREIQMKQQQRNRLGSGGSGDGPSVSWSRQ 406
PA PS P RA+R P + S GS G S +WSR
Sbjct: 502 SPPASPSIIPR-LRAIRLTPVDCGGS-------------------SSGSSSGGSGTWSRG 541
Query: 407 TQPPAALTGRGDAPNRSRNRSSSVDSFRSRCSSASSCSDLEDFSESLSRGGHRRRGKPPS 466
P G R+ SS++ + R L + S+ S GK P
Sbjct: 542 GPPKKEELVGGKKKGRTWGPSSTLQ--KERVGGEERLKGLGEGSKQWSSSA-PNLGKSPK 598
Query: 467 PTP 469
TP
Sbjct: 599 HTP 601
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 43.5 bits (101), Expect = 5e-04
Identities = 51/208 (24%), Positives = 81/208 (38%), Gaps = 15/208 (7%)
Query: 258 RSREEALAGRAARQEAEALRGLV---RGLELELRQERGLGHRVAGRRGQDCRRLAKELEE 314
+S+ ++ + R+ E RG V R E LRQ R G R + R +K ++
Sbjct: 295 KSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRS-RSRSKSKDK 353
Query: 315 AKASERSL---RARLKTLTSELALYKRGGRGSRGRGRPARPSPSPTGGRALRFDPTAFVK 371
K +RS R+R ++ + KRG + G + T R + K
Sbjct: 354 RKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSK 413
Query: 372 AKERKQREIQMKQQQRNRLGSGGSGDGPSVSWSRQTQPPAALTGRGDAPNRSRNRSSSVD 431
+E + E ++ + +G + + S S S P + P+ SR+RS S
Sbjct: 414 EREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKP-------NLPSESRSRSKSAS 466
Query: 432 SFRSRCSSASSCSDLEDFSESLSRGGHR 459
RSR S S + S S SR R
Sbjct: 467 KTRSRSKSRSRSASRSP-SRSRSRSHSR 493
Score = 32.3 bits (72), Expect = 1.1
Identities = 42/184 (22%), Positives = 71/184 (38%), Gaps = 29/184 (15%)
Query: 304 DCRRLAKELEEAKASERSLRARLKTLTSELALYKRGGRGSRGRGRPARPSPSPTGGRALR 363
D +R ++L+ + + R +R L K G R R R S S + R R
Sbjct: 152 DMKRALEKLDGTEVNGRKIR---------LVEDKPGSRRRRSYSRSRSHSRSRSRSRHSR 202
Query: 364 FDPTAFVKAKERKQREIQMKQQQRNRLGSGGSGDGPSVSWSRQTQPPAALTGRGDAPNRS 423
+++ + K + R+R GS S S SR + +P++
Sbjct: 203 KS-----RSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKE----KSRSPSKE 253
Query: 424 RNRSSSVDSFRSRCSSASSCSDLEDFSESLSRGGHRRRGKPPSPTPWSGSNMKSPPVERS 483
++RS S + +SR S + ++++ GKP S +P S KS RS
Sbjct: 254 KSRSRSHSAGKSRSKSKDQAEEKIQNNDNV--------GKPKSRSP---SRHKSKSKSRS 302
Query: 484 HHQK 487
Q+
Sbjct: 303 RSQE 306
Score = 30.4 bits (67), Expect = 4.2
Identities = 33/96 (34%), Positives = 44/96 (45%), Gaps = 15/96 (15%)
Query: 421 NRSRNRSSSVDSFRSRCSSASSCSDLEDFSESLSRGGHRRRGKPPSPTPWSGSNMK---- 476
+ SR+RS S S +SR S SS S S S SR G R R K S + + K
Sbjct: 190 SHSRSRSRSRHSRKSRSRSGSSKSS-HSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSR 248
Query: 477 SPPVERSHHQKSLANSGGWVPIKEYSSEHQAADMAE 512
SP E+S +S ++S G S ++ D AE
Sbjct: 249 SPSKEKS---RSRSHSAG-------KSRSKSKDQAE 274
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 43.5 bits (101), Expect = 5e-04
Identities = 47/165 (28%), Positives = 62/165 (37%), Gaps = 30/165 (18%)
Query: 344 RGRGRPARPSPSPTGGRALRFDPTAFVKAKERKQREIQMKQQQRNRLGSGGSGDGPSVSW 403
R R R PSP+P A P K+ +R R SG + + S S
Sbjct: 491 RERYRQRSPSPAPAPAPAAAAGPPT-------------RKKSRRERKRSGEAKEAASSSS 537
Query: 404 SRQTQPPAALTGRGDAPNRSRNR-----SSSVDSFRSRCSSASSCSDLEDFSESLSRGG- 457
Q PPA + +RSR+R +SS RSR S S + S RGG
Sbjct: 538 GTQPAPPAPASPWDSKKHRSRDRKPGSHASSSARRRSRSRSRSRSTRRRSRSTDRRRGGS 597
Query: 458 --------HRRRGKPPSPTPWSGSNMKSPPVERSHHQKSLANSGG 494
RRR + SP P + S+ S R H+ + GG
Sbjct: 598 RRSRSREKRRRRRRSASPPPATSSSSSS---RRERHRGKHRDGGG 639
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 43.1 bits (100), Expect = 6e-04
Identities = 33/113 (29%), Positives = 62/113 (54%), Gaps = 3/113 (2%)
Query: 218 RLQGLDGQNTRDTRENEIWHLREQVSRLASEKRELEAQLGRSREEALAGRAARQEAE-AL 276
+LQ D + + ++ + LR+Q+S SE+R LE QL R R++ A ++A+ +
Sbjct: 532 QLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREV 591
Query: 277 RGLVRGLELELRQERGLGH--RVAGRRGQDCRRLAKELEEAKASERSLRARLK 327
+ L EL R++ L H +VA ++ ++ R+ ++L+ A+ R R RL+
Sbjct: 592 QRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLE 644
Score = 42.4 bits (98), Expect = 0.001
Identities = 35/129 (27%), Positives = 65/129 (50%), Gaps = 8/129 (6%)
Query: 212 LKEELGRLQGLDG-----QNTRDTRENEIWHLREQVSRLASEKRELEAQL-GRSREEALA 265
L++E+ R QGL+G + ++ E ++ LR + S+L + +L QL GR +E A
Sbjct: 795 LEQEVAR-QGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQA 853
Query: 266 GRAARQEAEALRGLVRGLELELRQERGLGHRVAGRRGQDCRRLAKELEEAKASERSLRAR 325
R A+++ EAL R E ++ GL ++ ++ R L++E + + +L
Sbjct: 854 RREAQRQVEALERAAREKEALAKEHAGLAVQLVAAE-REGRTLSEEATRLRLEKEALEGS 912
Query: 326 LKTLTSELA 334
L + +LA
Sbjct: 913 LFEVQRQLA 921
Score = 39.7 bits (91), Expect = 0.007
Identities = 83/356 (23%), Positives = 139/356 (39%), Gaps = 44/356 (12%)
Query: 207 GIIRSLKEELGRLQGLDGQNTRDTRENEIWHLREQVSRLASEKRELEAQLGRSREEALAG 266
G+ R L E +L+ + Q R+ + E LR + A E+ L RS EE
Sbjct: 1172 GLRRELLEAQRKLR--ESQEGREVQRQEAGELRRSLGEGAKEREALR----RSNEEL--- 1222
Query: 267 RAARQEAEALRGLVRGLELELRQERGL---GHRVAGRRGQDCRRLAKELE----EAKASE 319
R+A ++AE+ R ++ + Q+ L G+ + R +E+E EA+
Sbjct: 1223 RSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARREL 1282
Query: 320 RSLRARLKTLTSELALYKRGGRGSRGR----GRPARPSPSPTGG---RALRFDPTAFVKA 372
+ LR ++K L SE R +GR R + S T G R L+ + + V
Sbjct: 1283 QELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMR 1342
Query: 373 KERK--QREIQMKQ-----QQRNRLGSGGSGDGPSVSWS----------RQTQPPAALTG 415
+E + QR++Q ++ ++R LGS G + AA G
Sbjct: 1343 QELQVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELKLEAARAEAAELG 1402
Query: 416 RGDAPNRSRNRSSSVDSFRSRCSSASSCSDLEDFSESLSRGGHRRRGKPPSPTPWSGSNM 475
+ R + + R ++ + L +L RG R P+P P GS
Sbjct: 1403 LRLSAAEGRAQGLEAELARVEVQRRAAEAQLGGLRSALRRGLGLGRAPSPAPRPVPGSPA 1462
Query: 476 KSPPVERS----HHQKSLANSGGWVPIKEYSSEHQAADMAEIDARLKALQEYMNRL 527
+ P E S + +L S G P + A+ + +A AL+E++ L
Sbjct: 1463 RDAPAEGSGEGLNSPSTLECSPGSQPPSPGPATSPASPDLDPEAVRGALREFLQEL 1518
Score = 33.5 bits (75), Expect = 0.50
Identities = 51/208 (24%), Positives = 79/208 (37%), Gaps = 36/208 (17%)
Query: 191 PLPLPYQGKPDPVVLQGIIRSLKEELGRLQGLDGQNTRDTRENEIWHLREQVSRLASEKR 250
P P DP ++G +R +EL Q RE + LR Q S L +
Sbjct: 1493 PATSPASPDLDPEAVRGALREFLQELRSAQ----------RERD--ELRTQTSALNRQLA 1540
Query: 251 ELEAQLGRSREEALAGRAARQEAEALRGLVRGLELELRQERGLGHRVAGRRGQDCRRLAK 310
E+EA+ + A + A E+E R V G R++G + + LA
Sbjct: 1541 EMEAERDSATSRARQLQKAVAESEEARRSVDG-------------RLSGVQAE----LAL 1583
Query: 311 ELEEAKASERSLRARL---KTLTSELALYKRGGRGSRGRGRPARPSPSPTGGRALRFDPT 367
+ E + SER RA L TL L + R S+ + + + + G R
Sbjct: 1584 QEESVRRSERERRATLDQVATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEV 1643
Query: 368 AFVKAKERKQREIQMK----QQQRNRLG 391
+ E+Q + + QR+RLG
Sbjct: 1644 LDASESRTVKLELQRRSLEGELQRSRLG 1671
Score = 33.1 bits (74), Expect = 0.65
Identities = 35/139 (25%), Positives = 53/139 (38%), Gaps = 8/139 (5%)
Query: 212 LKEELGRLQGL--DGQNTRDTRENEIWHLREQVSRLASEK----RELEAQLGRSREEALA 265
L EE+ LQ +G ++ + + L+E SEK R A + E
Sbjct: 1038 LSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKR 1097
Query: 266 GRAARQEAEALRGLVRGLELELRQERGLGHRVAGRRGQDCRRLAKELEEAKASERSLRAR 325
+RQE + R V L ELR R A Q+ RRL ++ + S
Sbjct: 1098 DAQSRQEQD--RSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLRE 1155
Query: 326 LKTLTSELALYKRGGRGSR 344
+ L ++L L + G R
Sbjct: 1156 AEELRTQLRLLEDARDGLR 1174
Score = 32.7 bits (73), Expect = 0.85
Identities = 37/129 (28%), Positives = 57/129 (44%), Gaps = 21/129 (16%)
Query: 211 SLKEELGRLQGLDGQNTRDTRENEIWHLREQVSRLASEKRELEAQLGRSREEALAGRAAR 270
SL++ L +L L+ +D + L V++L EK L+ GR R+ AR
Sbjct: 733 SLQDSLSKLSALNESLAQDKLD-----LNRLVAQLEEEKSALQ---GRQRQAEQEATVAR 784
Query: 271 QEAEALRGLVRGLELELRQERGLGHRVAGRRGQDCRRLAKELEEAKASE-RSLRARLKTL 329
+E E L EL L QE VA + + R+A++ +EA + +LR L
Sbjct: 785 EEQERLE------ELRLEQE------VARQGLEGSLRVAEQAQEALEQQLPTLRHERSQL 832
Query: 330 TSELALYKR 338
+LA R
Sbjct: 833 QEQLAQLSR 841
>gi|169234647 smoothelin-like 2 isoform 1 [Homo sapiens]
Length = 461
Score = 43.1 bits (100), Expect = 6e-04
Identities = 79/288 (27%), Positives = 111/288 (38%), Gaps = 56/288 (19%)
Query: 246 ASEKRELEAQLGRSREEALAGRAARQEAEALRGLVRGLELELRQERGLGHRVAGRRGQDC 305
A E R + LGR E AL G A R E +RGL RG+E + + R+AG
Sbjct: 7 AQEARTVREALGRY-EAALEG-AVRALHEDMRGLQRGVERRVAEAM----RLAGP----- 55
Query: 306 RRLAKELEEAKASERSLRARLKTLTSELALYKRGGRGSRGRGRPARPSPSPTGG---RAL 362
LA+ + + + + L+A+L+ LT ++ S G P PSP P G RA
Sbjct: 56 --LARTVADLQRDNQRLQAQLERLTRQVEALGLASGMSPVPGTPGTPSPPPAPGVPDRAP 113
Query: 363 RFDPTAFV-----------------KAKERKQREIQMKQQQRNRLGSG-GSGDGPSVSWS 404
R F +A E + R+ N G G GDGP
Sbjct: 114 RLGSARFASHATFSLSGRGQSLDHDEASESEMRKTSNSCIMENGHQPGAGPGDGP----- 168
Query: 405 RQTQPPAALTGRGDAPNRSRNRSSSVDSFRSRCSSASSCSDL---EDFSESLS-RGGHRR 460
P A P R R S S+ ++ + SD E + +LS
Sbjct: 169 ----PEIAQNFSAPDPPRPRPVSLSLRLPHQPVTAITRVSDRFSGETSAAALSPMSAATL 224
Query: 461 RGKPPSP----TPWSGSNMKSPPVERSHHQKSLANSG-GWVPIKEYSS 503
G PSP TPW+ SP + S S+ +SG G V ++S+
Sbjct: 225 GGLNPSPSEVITPWT----PSPSEKNSSFTWSVPSSGYGAVTASKHSN 268
>gi|32484977 angiomotin like 2 [Homo sapiens]
Length = 780
Score = 43.1 bits (100), Expect = 6e-04
Identities = 56/239 (23%), Positives = 102/239 (42%), Gaps = 26/239 (10%)
Query: 216 LGRLQGLDGQNTRDTRENE-IWHLREQVSRLASEKRELEAQLGRSREEALAGRAARQEAE 274
L +++ + +N R R+NE + E + A +LE+++ R E + A + E
Sbjct: 311 LAQMEAVLRENARLQRDNERLQRELESSAEKAGRIEKLESEIQRLSEAHESLTRASSKRE 370
Query: 275 ALRGLVRG-LELELRQERGLGHRVAGRRGQDCRRLAKELEEAKASERSLRARL------- 326
AL +R ++ E+R+ + + R RRLA + +EA+A + + A+L
Sbjct: 371 ALEKTMRNKMDSEMRRLQDFNRDLRERLESANRRLASKTQEAQAGSQDMVAKLLAQSYEQ 430
Query: 327 ----KTLTSELALYKRGGRGSRGRGRPARPSPSPTGGRALRFD-----PTAFVKAKERKQ 377
+ L E+AL + R R + GRA R + A+V+ ER Q
Sbjct: 431 QQEQEKLEREMALLRGAIEDQRRRAELLEQALGNAQGRAARAEEELRKKQAYVEKVERLQ 490
Query: 378 REI-------QMKQQQRNRLGSGGSGDGPSV-SWSRQTQPPAALTGRGDAPNRSRNRSS 428
+ + + ++Q RL + + ++ + RQ P +G G +P S R S
Sbjct: 491 QALGQLQAACEKREQLELRLRTRLEQELKALRAQQRQAGAPGGSSGSGGSPELSALRLS 549
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 42.7 bits (99), Expect = 8e-04
Identities = 57/241 (23%), Positives = 89/241 (36%), Gaps = 39/241 (16%)
Query: 209 IRSLKEELGRLQGLDGQNTRDTRENEIWHLREQVSRL-----ASEKREL--EAQLGRSRE 261
++ EE R+ Q R + L EQ+ + A EK L EA++ R
Sbjct: 1204 LKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRA 1263
Query: 262 EALAGRAARQEAEALRGLVRGLELELRQERGL---GHRVAGRRGQDCRRLAKELEEAKAS 318
E + + ARQE E R R LEL+L++ +G G R + +R ELE +
Sbjct: 1264 ELSSLQTARQEGEQRR---RRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGA 1320
Query: 319 ERSLRARLKTLTSELA-----------LYKRGGRGSRGRGRPARPSPSPTGGRALRFDPT 367
++ L+ EL+ L + R G R + G + +
Sbjct: 1321 LNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEE 1380
Query: 368 AFVKAKERKQREIQMKQQQRNRLGSGGSGDGPSVSWSRQTQPPAALTGRGDAPNRSRNRS 427
A A+ER RE+Q Q Q + W R+ + A G+ R R
Sbjct: 1381 A--AARERAGRELQTAQAQLS-------------EWRRRQEEEAGALEAGEEARRRAARE 1425
Query: 428 S 428
+
Sbjct: 1426 A 1426
Score = 38.1 bits (87), Expect = 0.020
Identities = 46/205 (22%), Positives = 81/205 (39%), Gaps = 34/205 (16%)
Query: 155 RKMGGRPGSLAPR------SAQLNSKRYLILIYSVEFDRIHYPLPLPYQGKPDPVVLQGI 208
R++ GR G L +++L + RY L+ VE + K + Q
Sbjct: 1757 RQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQ-- 1814
Query: 209 IRSLKEELGRLQGLDGQNTRDTRENEIWHLREQVSRLASEKRELEAQLGRSREEALAGRA 268
L+ ++ L+G G+ R + S+LA + +LE + +RE L+G+
Sbjct: 1815 ---LERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQE---TRERILSGKL 1868
Query: 269 ARQEAEALRGLVRGLELE--------------------LRQERGLGHRVAGRRGQDCRRL 308
R+ + L+ +V +E E L+++ A R RRL
Sbjct: 1869 VRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRL 1928
Query: 309 AKELEEAKASERSLRARLKTLTSEL 333
+ELE+ S S+ + TL + L
Sbjct: 1929 QRELEDVTESAESMNREVTTLRNRL 1953
Score = 37.0 bits (84), Expect = 0.045
Identities = 67/239 (28%), Positives = 94/239 (39%), Gaps = 59/239 (24%)
Query: 210 RSLKEELGRLQGLDGQNTRDTRENEIWHLREQVSRLASEKRELEAQLGRSREEALAGRA- 268
R KEE GR Q L+ R + E L+EQ+ EL AQLGR EE A A
Sbjct: 1067 RLRKEEKGR-QELEKLKRR--LDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALAR 1123
Query: 269 ARQEAEALRGLVRGL------------ELEL---------RQERGLGHRVAGRRG----- 302
A E A L++ L +LE +Q R LG + RG
Sbjct: 1124 AEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDT 1183
Query: 303 ---------------QDCRRLAKELEEA----KASERSLRARLKTLTSELA---LYKRGG 340
Q+ L K LEE +A+ + LR R ELA R G
Sbjct: 1184 LDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRG 1243
Query: 341 RGSRGRGRPARPSPSPTGGRALRFDPTAFVKAKERKQR-EIQMKQQQRNRLGSGGSGDG 398
+G+ + R A + L TA + ++R++R E+Q+++ Q G +GDG
Sbjct: 1244 KGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQ------GRAGDG 1296
Score = 32.7 bits (73), Expect = 0.85
Identities = 44/181 (24%), Positives = 70/181 (38%), Gaps = 19/181 (10%)
Query: 239 REQVSRLASEKRELEAQLGRSREEALAGRAARQEAEALRGLVRGLELELRQ-ERGLGHRV 297
RE+ +R S R LE + E RA R E EAL + + + ER RV
Sbjct: 1504 REREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERAC--RV 1561
Query: 298 AGRRGQDCRRLAKELEEAKASERSLRARLKTLTSEL-ALYKRGGRGSRGRGRPARPSPSP 356
A + D R ELE+ + + RL+ L ++R +G G R
Sbjct: 1562 AEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQ--- 1618
Query: 357 TGGRALRFDPTAFVKAKERKQREIQMK---------QQQRNRLGSGGSGDGPSVSWSRQT 407
A + + +ERKQR + + ++ + ++ S G G +V R+
Sbjct: 1619 ---LAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKM 1675
Query: 408 Q 408
Q
Sbjct: 1676 Q 1676
Score = 32.3 bits (72), Expect = 1.1
Identities = 47/191 (24%), Positives = 74/191 (38%), Gaps = 36/191 (18%)
Query: 205 LQGIIRSLKEELGRLQGL--DGQNTRDTRENEIWHLREQVSRLASEKRELEAQLGRSREE 262
L+ + L+EEL Q RD +E+ + + + EKR+LE +LG+ EE
Sbjct: 1710 LEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEE 1769
Query: 263 ALAGRAARQEAEALRGLVRGLELELRQERGLGHRVAGRRGQDCRRLAKELEEAKASERSL 322
+ +E L R L L++ L EL ++ERS
Sbjct: 1770 L---EEEQSNSELLNDRYRKLLLQVES------------------LTTEL----SAERSF 1804
Query: 323 RARLKTLTSELALYKRGGRGSRGRGRPARPSPSPTGGRALRFDPTAFVKAKERKQREIQM 382
A+ ++ +L + RG G G RA R T + Q E Q+
Sbjct: 1805 SAKAESGRQQLERQIQELRGRLGE--------EDAGARA-RHKMTIAALESKLAQAEEQL 1855
Query: 383 KQQQRNRLGSG 393
+Q+ R R+ SG
Sbjct: 1856 EQETRERILSG 1866
Score = 30.4 bits (67), Expect = 4.2
Identities = 38/142 (26%), Positives = 69/142 (48%), Gaps = 24/142 (16%)
Query: 208 IIRSLKEELGRLQGLDGQNTRDTRENEIWHLREQVSRLASEKRELEAQLGRSREEALAGR 267
++++ +EL ++Q L Q+ R E+ L+ +V++L E+ L QL R+ E A
Sbjct: 878 VLQARAQELQKVQELQQQSAR-----EVGELQGRVAQLEEERARLAEQL-RAEAELCA-- 929
Query: 268 AARQEAEALRGLV----RGLEL---ELRQERGLGHRVAGRRGQDCRRLAKELEEAKA--- 317
EAE RG + + LEL EL G + + + +RL + ++E +A
Sbjct: 930 ----EAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLE 985
Query: 318 SERSLRAR--LKTLTSELALYK 337
+E R + L+ +T+E + K
Sbjct: 986 AEEGARQKLQLEKVTTEAKMKK 1007
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 42.7 bits (99), Expect = 8e-04
Identities = 57/241 (23%), Positives = 89/241 (36%), Gaps = 39/241 (16%)
Query: 209 IRSLKEELGRLQGLDGQNTRDTRENEIWHLREQVSRL-----ASEKREL--EAQLGRSRE 261
++ EE R+ Q R + L EQ+ + A EK L EA++ R
Sbjct: 1196 LKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRA 1255
Query: 262 EALAGRAARQEAEALRGLVRGLELELRQERGL---GHRVAGRRGQDCRRLAKELEEAKAS 318
E + + ARQE E R R LEL+L++ +G G R + +R ELE +
Sbjct: 1256 ELSSLQTARQEGEQRR---RRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGA 1312
Query: 319 ERSLRARLKTLTSELA-----------LYKRGGRGSRGRGRPARPSPSPTGGRALRFDPT 367
++ L+ EL+ L + R G R + G + +
Sbjct: 1313 LNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEE 1372
Query: 368 AFVKAKERKQREIQMKQQQRNRLGSGGSGDGPSVSWSRQTQPPAALTGRGDAPNRSRNRS 427
A A+ER RE+Q Q Q + W R+ + A G+ R R
Sbjct: 1373 A--AARERAGRELQTAQAQLS-------------EWRRRQEEEAGALEAGEEARRRAARE 1417
Query: 428 S 428
+
Sbjct: 1418 A 1418
Score = 38.1 bits (87), Expect = 0.020
Identities = 46/205 (22%), Positives = 81/205 (39%), Gaps = 34/205 (16%)
Query: 155 RKMGGRPGSLAPR------SAQLNSKRYLILIYSVEFDRIHYPLPLPYQGKPDPVVLQGI 208
R++ GR G L +++L + RY L+ VE + K + Q
Sbjct: 1749 RQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQ-- 1806
Query: 209 IRSLKEELGRLQGLDGQNTRDTRENEIWHLREQVSRLASEKRELEAQLGRSREEALAGRA 268
L+ ++ L+G G+ R + S+LA + +LE + +RE L+G+
Sbjct: 1807 ---LERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQE---TRERILSGKL 1860
Query: 269 ARQEAEALRGLVRGLELE--------------------LRQERGLGHRVAGRRGQDCRRL 308
R+ + L+ +V +E E L+++ A R RRL
Sbjct: 1861 VRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRL 1920
Query: 309 AKELEEAKASERSLRARLKTLTSEL 333
+ELE+ S S+ + TL + L
Sbjct: 1921 QRELEDVTESAESMNREVTTLRNRL 1945
Score = 37.0 bits (84), Expect = 0.045
Identities = 67/239 (28%), Positives = 94/239 (39%), Gaps = 59/239 (24%)
Query: 210 RSLKEELGRLQGLDGQNTRDTRENEIWHLREQVSRLASEKRELEAQLGRSREEALAGRA- 268
R KEE GR Q L+ R + E L+EQ+ EL AQLGR EE A A
Sbjct: 1059 RLRKEEKGR-QELEKLKRR--LDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALAR 1115
Query: 269 ARQEAEALRGLVRGL------------ELEL---------RQERGLGHRVAGRRG----- 302
A E A L++ L +LE +Q R LG + RG
Sbjct: 1116 AEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDT 1175
Query: 303 ---------------QDCRRLAKELEEA----KASERSLRARLKTLTSELA---LYKRGG 340
Q+ L K LEE +A+ + LR R ELA R G
Sbjct: 1176 LDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRG 1235
Query: 341 RGSRGRGRPARPSPSPTGGRALRFDPTAFVKAKERKQR-EIQMKQQQRNRLGSGGSGDG 398
+G+ + R A + L TA + ++R++R E+Q+++ Q G +GDG
Sbjct: 1236 KGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQ------GRAGDG 1288
Score = 32.7 bits (73), Expect = 0.85
Identities = 44/181 (24%), Positives = 70/181 (38%), Gaps = 19/181 (10%)
Query: 239 REQVSRLASEKRELEAQLGRSREEALAGRAARQEAEALRGLVRGLELELRQ-ERGLGHRV 297
RE+ +R S R LE + E RA R E EAL + + + ER RV
Sbjct: 1496 REREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERAC--RV 1553
Query: 298 AGRRGQDCRRLAKELEEAKASERSLRARLKTLTSEL-ALYKRGGRGSRGRGRPARPSPSP 356
A + D R ELE+ + + RL+ L ++R +G G R
Sbjct: 1554 AEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQ--- 1610
Query: 357 TGGRALRFDPTAFVKAKERKQREIQMK---------QQQRNRLGSGGSGDGPSVSWSRQT 407
A + + +ERKQR + + ++ + ++ S G G +V R+
Sbjct: 1611 ---LAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKM 1667
Query: 408 Q 408
Q
Sbjct: 1668 Q 1668
Score = 32.3 bits (72), Expect = 1.1
Identities = 47/191 (24%), Positives = 74/191 (38%), Gaps = 36/191 (18%)
Query: 205 LQGIIRSLKEELGRLQGL--DGQNTRDTRENEIWHLREQVSRLASEKRELEAQLGRSREE 262
L+ + L+EEL Q RD +E+ + + + EKR+LE +LG+ EE
Sbjct: 1702 LEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEE 1761
Query: 263 ALAGRAARQEAEALRGLVRGLELELRQERGLGHRVAGRRGQDCRRLAKELEEAKASERSL 322
+ +E L R L L++ L EL ++ERS
Sbjct: 1762 L---EEEQSNSELLNDRYRKLLLQVES------------------LTTEL----SAERSF 1796
Query: 323 RARLKTLTSELALYKRGGRGSRGRGRPARPSPSPTGGRALRFDPTAFVKAKERKQREIQM 382
A+ ++ +L + RG G G RA R T + Q E Q+
Sbjct: 1797 SAKAESGRQQLERQIQELRGRLGE--------EDAGARA-RHKMTIAALESKLAQAEEQL 1847
Query: 383 KQQQRNRLGSG 393
+Q+ R R+ SG
Sbjct: 1848 EQETRERILSG 1858
Score = 30.4 bits (67), Expect = 4.2
Identities = 38/142 (26%), Positives = 69/142 (48%), Gaps = 24/142 (16%)
Query: 208 IIRSLKEELGRLQGLDGQNTRDTRENEIWHLREQVSRLASEKRELEAQLGRSREEALAGR 267
++++ +EL ++Q L Q+ R E+ L+ +V++L E+ L QL R+ E A
Sbjct: 870 VLQARAQELQKVQELQQQSAR-----EVGELQGRVAQLEEERARLAEQL-RAEAELCA-- 921
Query: 268 AARQEAEALRGLV----RGLEL---ELRQERGLGHRVAGRRGQDCRRLAKELEEAKA--- 317
EAE RG + + LEL EL G + + + +RL + ++E +A
Sbjct: 922 ----EAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLE 977
Query: 318 SERSLRAR--LKTLTSELALYK 337
+E R + L+ +T+E + K
Sbjct: 978 AEEGARQKLQLEKVTTEAKMKK 999
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 42.7 bits (99), Expect = 8e-04
Identities = 57/241 (23%), Positives = 89/241 (36%), Gaps = 39/241 (16%)
Query: 209 IRSLKEELGRLQGLDGQNTRDTRENEIWHLREQVSRL-----ASEKREL--EAQLGRSRE 261
++ EE R+ Q R + L EQ+ + A EK L EA++ R
Sbjct: 1237 LKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRA 1296
Query: 262 EALAGRAARQEAEALRGLVRGLELELRQERGL---GHRVAGRRGQDCRRLAKELEEAKAS 318
E + + ARQE E R R LEL+L++ +G G R + +R ELE +
Sbjct: 1297 ELSSLQTARQEGEQRR---RRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGA 1353
Query: 319 ERSLRARLKTLTSELA-----------LYKRGGRGSRGRGRPARPSPSPTGGRALRFDPT 367
++ L+ EL+ L + R G R + G + +
Sbjct: 1354 LNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEE 1413
Query: 368 AFVKAKERKQREIQMKQQQRNRLGSGGSGDGPSVSWSRQTQPPAALTGRGDAPNRSRNRS 427
A A+ER RE+Q Q Q + W R+ + A G+ R R
Sbjct: 1414 A--AARERAGRELQTAQAQLS-------------EWRRRQEEEAGALEAGEEARRRAARE 1458
Query: 428 S 428
+
Sbjct: 1459 A 1459
Score = 38.1 bits (87), Expect = 0.020
Identities = 46/205 (22%), Positives = 81/205 (39%), Gaps = 34/205 (16%)
Query: 155 RKMGGRPGSLAPR------SAQLNSKRYLILIYSVEFDRIHYPLPLPYQGKPDPVVLQGI 208
R++ GR G L +++L + RY L+ VE + K + Q
Sbjct: 1790 RQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQ-- 1847
Query: 209 IRSLKEELGRLQGLDGQNTRDTRENEIWHLREQVSRLASEKRELEAQLGRSREEALAGRA 268
L+ ++ L+G G+ R + S+LA + +LE + +RE L+G+
Sbjct: 1848 ---LERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQE---TRERILSGKL 1901
Query: 269 ARQEAEALRGLVRGLELE--------------------LRQERGLGHRVAGRRGQDCRRL 308
R+ + L+ +V +E E L+++ A R RRL
Sbjct: 1902 VRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRL 1961
Query: 309 AKELEEAKASERSLRARLKTLTSEL 333
+ELE+ S S+ + TL + L
Sbjct: 1962 QRELEDVTESAESMNREVTTLRNRL 1986
Score = 37.0 bits (84), Expect = 0.045
Identities = 67/239 (28%), Positives = 94/239 (39%), Gaps = 59/239 (24%)
Query: 210 RSLKEELGRLQGLDGQNTRDTRENEIWHLREQVSRLASEKRELEAQLGRSREEALAGRA- 268
R KEE GR Q L+ R + E L+EQ+ EL AQLGR EE A A
Sbjct: 1100 RLRKEEKGR-QELEKLKRR--LDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALAR 1156
Query: 269 ARQEAEALRGLVRGL------------ELEL---------RQERGLGHRVAGRRG----- 302
A E A L++ L +LE +Q R LG + RG
Sbjct: 1157 AEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDT 1216
Query: 303 ---------------QDCRRLAKELEEA----KASERSLRARLKTLTSELA---LYKRGG 340
Q+ L K LEE +A+ + LR R ELA R G
Sbjct: 1217 LDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRG 1276
Query: 341 RGSRGRGRPARPSPSPTGGRALRFDPTAFVKAKERKQR-EIQMKQQQRNRLGSGGSGDG 398
+G+ + R A + L TA + ++R++R E+Q+++ Q G +GDG
Sbjct: 1277 KGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQ------GRAGDG 1329
Score = 32.7 bits (73), Expect = 0.85
Identities = 44/181 (24%), Positives = 70/181 (38%), Gaps = 19/181 (10%)
Query: 239 REQVSRLASEKRELEAQLGRSREEALAGRAARQEAEALRGLVRGLELELRQ-ERGLGHRV 297
RE+ +R S R LE + E RA R E EAL + + + ER RV
Sbjct: 1537 REREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERAC--RV 1594
Query: 298 AGRRGQDCRRLAKELEEAKASERSLRARLKTLTSEL-ALYKRGGRGSRGRGRPARPSPSP 356
A + D R ELE+ + + RL+ L ++R +G G R
Sbjct: 1595 AEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQ--- 1651
Query: 357 TGGRALRFDPTAFVKAKERKQREIQMK---------QQQRNRLGSGGSGDGPSVSWSRQT 407
A + + +ERKQR + + ++ + ++ S G G +V R+
Sbjct: 1652 ---LAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKM 1708
Query: 408 Q 408
Q
Sbjct: 1709 Q 1709
Score = 32.3 bits (72), Expect = 1.1
Identities = 47/191 (24%), Positives = 74/191 (38%), Gaps = 36/191 (18%)
Query: 205 LQGIIRSLKEELGRLQGL--DGQNTRDTRENEIWHLREQVSRLASEKRELEAQLGRSREE 262
L+ + L+EEL Q RD +E+ + + + EKR+LE +LG+ EE
Sbjct: 1743 LEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEE 1802
Query: 263 ALAGRAARQEAEALRGLVRGLELELRQERGLGHRVAGRRGQDCRRLAKELEEAKASERSL 322
+ +E L R L L++ L EL ++ERS
Sbjct: 1803 L---EEEQSNSELLNDRYRKLLLQVES------------------LTTEL----SAERSF 1837
Query: 323 RARLKTLTSELALYKRGGRGSRGRGRPARPSPSPTGGRALRFDPTAFVKAKERKQREIQM 382
A+ ++ +L + RG G G RA R T + Q E Q+
Sbjct: 1838 SAKAESGRQQLERQIQELRGRLGE--------EDAGARA-RHKMTIAALESKLAQAEEQL 1888
Query: 383 KQQQRNRLGSG 393
+Q+ R R+ SG
Sbjct: 1889 EQETRERILSG 1899
Score = 30.4 bits (67), Expect = 4.2
Identities = 38/142 (26%), Positives = 69/142 (48%), Gaps = 24/142 (16%)
Query: 208 IIRSLKEELGRLQGLDGQNTRDTRENEIWHLREQVSRLASEKRELEAQLGRSREEALAGR 267
++++ +EL ++Q L Q+ R E+ L+ +V++L E+ L QL R+ E A
Sbjct: 911 VLQARAQELQKVQELQQQSAR-----EVGELQGRVAQLEEERARLAEQL-RAEAELCA-- 962
Query: 268 AARQEAEALRGLV----RGLEL---ELRQERGLGHRVAGRRGQDCRRLAKELEEAKA--- 317
EAE RG + + LEL EL G + + + +RL + ++E +A
Sbjct: 963 ----EAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLE 1018
Query: 318 SERSLRAR--LKTLTSELALYK 337
+E R + L+ +T+E + K
Sbjct: 1019 AEEGARQKLQLEKVTTEAKMKK 1040
>gi|154090997 coiled-coil domain containing 13 [Homo sapiens]
Length = 715
Score = 42.4 bits (98), Expect = 0.001
Identities = 45/150 (30%), Positives = 75/150 (50%), Gaps = 23/150 (15%)
Query: 205 LQGIIRSLKEELGRLQGLDGQNT-RDTRENEI------WHLR-EQVSRLASEKRELEAQL 256
L+ I+S+K+EL Q + + D ++ W R +Q+ L S+ +ELE QL
Sbjct: 224 LRNQIQSVKQELRMAQKVLAREVGEDINVQQLLSSPGTWRGRAQQILVLQSKVQELEKQL 283
Query: 257 GRSREEALAGRAA---------RQEAEALRGLVRGLELELRQERGLGHRVAGRRGQDCRR 307
G++R ++ AG A+ R+ + + L+R LE ++ GL ++A R
Sbjct: 284 GQARSQS-AGTASDELSVYPDPRKLSAQEKNLLRIRSLEREKQEGL-EKLASERDV---- 337
Query: 308 LAKELEEAKASERSLRARLKTLTSELALYK 337
L +ELEE K +R+R K L+SE+ K
Sbjct: 338 LQRELEELKKKFEGMRSRNKLLSSEMKTLK 367
>gi|16262452 cingulin [Homo sapiens]
Length = 1203
Score = 42.0 bits (97), Expect = 0.001
Identities = 39/128 (30%), Positives = 60/128 (46%), Gaps = 11/128 (8%)
Query: 207 GIIRSLKEELGRLQGLDGQNTRDTRENEIWHLREQVSRLASEKRELEAQLGRSREEALAG 266
G+ + LKE G + G + R LR+++ RL +EK++LE L S+EE +
Sbjct: 741 GLEQQLKETRGLVDGGEAVEAR---------LRDKLQRLEAEKQQLEEALNASQEEEGSL 791
Query: 267 RAARQEAEA-LRGLVRGLELELRQERGLGHRVAGRRGQDCRRLAKELEEAKASERSLRAR 325
AA++ EA L RGL L QE+ +R G+ L + E + +R L
Sbjct: 792 AAAKRALEARLEEAQRGL-ARLGQEQQTLNRALEEEGKQREVLRRGKAELEEQKRLLDRT 850
Query: 326 LKTLTSEL 333
+ L EL
Sbjct: 851 VDRLNKEL 858
Score = 36.6 bits (83), Expect = 0.059
Identities = 42/142 (29%), Positives = 64/142 (45%), Gaps = 16/142 (11%)
Query: 212 LKEELGRLQGLDGQNTRDTRENEIWHLREQVSRLASEKRELEAQ---LGRSREEALAG-R 267
L+ E R + L+ QN + + + LR+ + K EA+ LG+ R R
Sbjct: 669 LRVEADRGRELEEQNLQ--LQKTLQQLRQDCEEASKAKMVAEAEATVLGQRRAAVETTLR 726
Query: 268 AARQEAEALRGLVRGLELELRQERGL---GHRVAGRRGQDCRRLAKE---LEEA----KA 317
++E + R + GLE +L++ RGL G V R +RL E LEEA +
Sbjct: 727 ETQEENDEFRRRILGLEQQLKETRGLVDGGEAVEARLRDKLQRLEAEKQQLEEALNASQE 786
Query: 318 SERSLRARLKTLTSELALYKRG 339
E SL A + L + L +RG
Sbjct: 787 EEGSLAAAKRALEARLEEAQRG 808
Score = 35.0 bits (79), Expect = 0.17
Identities = 33/117 (28%), Positives = 51/117 (43%), Gaps = 16/117 (13%)
Query: 205 LQGIIRSLKEELGRLQGLDGQNTRDTRENEIWHLREQVSRLASEKRELEAQLG------- 257
LQ + EE G Q + +N D R ++++ +L EK E+E +LG
Sbjct: 557 LQRELEETSEETGHWQSMFQKNKEDLRAT-----KQELLQLRMEKEEMEEELGEKIEVLQ 611
Query: 258 RSREEALAGRAARQEAEALRGLVRGLELELR--QERGLGHRVAGRRGQDCRRLAKEL 312
R E+A A ++ E L+ + + EL+ Q VAGR R L K+L
Sbjct: 612 RELEQARASAGDTRQVEVLKKELLRTQEELKELQAERQSQEVAGRHRD--RELEKQL 666
Score = 32.3 bits (72), Expect = 1.1
Identities = 40/154 (25%), Positives = 65/154 (42%), Gaps = 38/154 (24%)
Query: 209 IRSLKEELGRLQGLDGQNTRDTRENEIWHLREQVSRLASEKRELEAQLGRSREEALAGRA 268
+R + EL L+G + +R+ E+ H+R+Q R QL RS ++A A
Sbjct: 490 LRLRERELTALKGALKEEVA-SRDQEVEHVRQQYQRDTE-------QLRRSMQDATQDHA 541
Query: 269 ARQ-EAEALRGLVRGLELELRQ---ERGLGHRVAGRRGQDCRR----------------- 307
+ E + + LVRGL+ EL + E G + + +D R
Sbjct: 542 VLEAERQKMSALVRGLQRELEETSEETGHWQSMFQKNKEDLRATKQELLQLRMEKEEMEE 601
Query: 308 --------LAKELEEAKASERSLRARLKTLTSEL 333
L +ELE+A+AS R +++ L EL
Sbjct: 602 ELGEKIEVLQRELEQARASAGDTR-QVEVLKKEL 634
>gi|239754489 PREDICTED: hypothetical protein [Homo sapiens]
Length = 228
Score = 41.6 bits (96), Expect = 0.002
Identities = 42/132 (31%), Positives = 48/132 (36%), Gaps = 11/132 (8%)
Query: 292 GLGHRVAGRRGQDCRRLAKELEEAKASERSLRARLKTLTSELALYKRGGRGSRGRGRPAR 351
G H AGRR Q R A +RA L +RGGRG RG GR +
Sbjct: 90 GAQHWAAGRRAQ---REQGAGAAVLADFGHVRAAPSGLRRRRLQRRRGGRGGRGAGRARK 146
Query: 352 PSPSPTGGRALRFDPTAFVKAKERKQREIQMKQQQRNRLGSG-----GSGDGPSVSWSRQ 406
P P G A R P R + R G G G GP SW+R+
Sbjct: 147 PGPDRAG--AERSLPAHRAPRLARPPVPPSVAHVARASAGLGARPVPGGPAGPRESWARR 204
Query: 407 T-QPPAALTGRG 417
T PP G G
Sbjct: 205 TSSPPRGAAGGG 216
>gi|239749695 PREDICTED: hypothetical protein XP_002347121 [Homo
sapiens]
Length = 594
Score = 41.6 bits (96), Expect = 0.002
Identities = 50/185 (27%), Positives = 71/185 (38%), Gaps = 20/185 (10%)
Query: 298 AGRRGQDCRRLAKELEEAKAS-ERSLRARLKTLTSELALYKRGGRGSR----GRGRPARP 352
AG R + R E A E RARL +++ +R G G+R GRG +
Sbjct: 360 AGARVGEAREAVTTHERAHLDREGEARARLGQAAAQM---RREGWGARAKLGGRGVCGKC 416
Query: 353 SPSPTGGRALRFDPTAFVKAKERKQREIQMKQQQRNRLGSGGSGDGPSV-----SWSRQT 407
P P A R +P A +AK QR + + + +++GS G G GP R
Sbjct: 417 GPGPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRGRGWGPGAGRVPSGGRRGV 476
Query: 408 QPPAALTGRGDAPNRSR---NRSSSVDSFRSRCSSASSCSDLEDFSESLSRGGHRRRGKP 464
P G AP SR +VD R + + + + +G G P
Sbjct: 477 GNPERWGGEAAAPRPSRVLLPELPAVDPARDTRREPDAAAQRTELGGRVGKG----PGAP 532
Query: 465 PSPTP 469
PS P
Sbjct: 533 PSALP 537
>gi|239743961 PREDICTED: hypothetical protein XP_002344246 [Homo
sapiens]
Length = 594
Score = 41.6 bits (96), Expect = 0.002
Identities = 50/185 (27%), Positives = 71/185 (38%), Gaps = 20/185 (10%)
Query: 298 AGRRGQDCRRLAKELEEAKAS-ERSLRARLKTLTSELALYKRGGRGSR----GRGRPARP 352
AG R + R E A E RARL +++ +R G G+R GRG +
Sbjct: 360 AGARVGEAREAVTTHERAHLDREGEARARLGQAAAQM---RREGWGARAKLGGRGVCGKC 416
Query: 353 SPSPTGGRALRFDPTAFVKAKERKQREIQMKQQQRNRLGSGGSGDGPSV-----SWSRQT 407
P P A R +P A +AK QR + + + +++GS G G GP R
Sbjct: 417 GPGPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRGRGWGPGAGRVPSGGRRGV 476
Query: 408 QPPAALTGRGDAPNRSR---NRSSSVDSFRSRCSSASSCSDLEDFSESLSRGGHRRRGKP 464
P G AP SR +VD R + + + + +G G P
Sbjct: 477 GNPERWGGEAAAPRPSRVLLPELPAVDPARDTRREPDAAAQRTELGGRVGKG----PGAP 532
Query: 465 PSPTP 469
PS P
Sbjct: 533 PSALP 537
>gi|239743069 PREDICTED: hypothetical protein XP_002342750 [Homo
sapiens]
Length = 231
Score = 41.6 bits (96), Expect = 0.002
Identities = 42/132 (31%), Positives = 48/132 (36%), Gaps = 11/132 (8%)
Query: 292 GLGHRVAGRRGQDCRRLAKELEEAKASERSLRARLKTLTSELALYKRGGRGSRGRGRPAR 351
G H AGRR Q R A +RA L +RGGRG RG GR +
Sbjct: 93 GAQHWAAGRRAQ---REQGAGAAVLADFGHVRAAPSGLRRRRLQRRRGGRGGRGAGRARK 149
Query: 352 PSPSPTGGRALRFDPTAFVKAKERKQREIQMKQQQRNRLGSG-----GSGDGPSVSWSRQ 406
P P G A R P R + R G G G GP SW+R+
Sbjct: 150 PGPDRAG--AERSLPAHRAPRLARPPVPPSVAHVARASAGLGARPVPGGPAGPRESWARR 207
Query: 407 T-QPPAALTGRG 417
T PP G G
Sbjct: 208 TSSPPRGAAGGG 219
>gi|239508715 PREDICTED: hypothetical protein [Homo sapiens]
Length = 231
Score = 41.6 bits (96), Expect = 0.002
Identities = 42/132 (31%), Positives = 48/132 (36%), Gaps = 11/132 (8%)
Query: 292 GLGHRVAGRRGQDCRRLAKELEEAKASERSLRARLKTLTSELALYKRGGRGSRGRGRPAR 351
G H AGRR Q R A +RA L +RGGRG RG GR +
Sbjct: 93 GAQHWAAGRRAQ---REQGAGAAVLADFGHVRAAPSGLRRRRLQRRRGGRGGRGAGRARK 149
Query: 352 PSPSPTGGRALRFDPTAFVKAKERKQREIQMKQQQRNRLGSG-----GSGDGPSVSWSRQ 406
P P G A R P R + R G G G GP SW+R+
Sbjct: 150 PGPDRAG--AERSLPAHRAPRLARPPVPPSVAHVARASAGLGARPVPGGPAGPRESWARR 207
Query: 407 T-QPPAALTGRG 417
T PP G G
Sbjct: 208 TSSPPRGAAGGG 219
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 40.8 bits (94), Expect = 0.003
Identities = 53/201 (26%), Positives = 85/201 (42%), Gaps = 22/201 (10%)
Query: 291 RGLGHRVAGRRGQDCRRLAKELEEAKASERSLRARLKTLT-SELALYKRGGRGSRGRGRP 349
RGL R R ++ R + + + +S+ + R R ++ + S + +RGG G R P
Sbjct: 1768 RGL-QRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRS-P 1825
Query: 350 ARPSPSPTGGRALRFDPTAFVKAKERKQREIQMKQQQRNRLGSGGSGDGPSVSWSRQTQP 409
AR S T R R +++R + +R+R + S + R+++
Sbjct: 1826 ARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRA-------SPATHRRSRS 1878
Query: 410 PAALTGRGDAPNRSRNRSSSVDSFRSRCSSA----SSCSDLEDFSESLSRGGH----RRR 461
L R RSR+R+S V RSR ++ S S S SR RRR
Sbjct: 1879 RTPLISR----RRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRR 1934
Query: 462 GKPPSPTPWSGSNMKSPPVER 482
+ +PT S ++PPV R
Sbjct: 1935 SRSRTPTTRRRSRSRTPPVTR 1955
Score = 36.2 bits (82), Expect = 0.077
Identities = 49/178 (27%), Positives = 63/178 (35%), Gaps = 32/178 (17%)
Query: 341 RGSRGRGRPARPSPSPTGGRALRFDPTAFVKAK-ERKQR------EIQMKQQQRNRLGSG 393
RGSR P S +P R+ R P KA+ R+ R E + + R+R
Sbjct: 1670 RGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPS 1729
Query: 394 GSGDGP-----SVSWSRQTQPPAALT----GRGDAP---------NRSRNRSSSVDSFRS 435
S P S R P T GR +P +RSR + R
Sbjct: 1730 VSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRD 1789
Query: 436 RCSSASSCSDLEDFSESLSRGGHRRRGKPPSPTPWSGSNMKSPPVERSHHQKSLANSG 493
R S+ S S S S SR RRRG SG + +SP + S S G
Sbjct: 1790 RSGSSQSTSRRRQRSRSRSRVTRRRRG-------GSGYHSRSPARQESSRTSSRRRRG 1840
Score = 35.4 bits (80), Expect = 0.13
Identities = 42/159 (26%), Positives = 58/159 (36%), Gaps = 16/159 (10%)
Query: 339 GGRGSRGRGRPARPSPSPTGGRALRFDPTAFVKAKER---KQR-------EIQMKQQQRN 388
G R G + PS + D + KAK R +QR E+ K +
Sbjct: 1534 GQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSP 1593
Query: 389 RLGSGGSG----DGPSVSWSRQTQPPAALTGRGDAPNRSRNRSSSVDSFRSRCSSASSCS 444
R GS D P + Q+ ++ + AP RS S S + R S S
Sbjct: 1594 RRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSS 1653
Query: 445 DLEDFSESLSRGGHRRRGKPPSPTPWSGSNMKSPPVERS 483
E E + RRG SP P + S ++PP RS
Sbjct: 1654 STESSPEHPPKSRTARRGSRSSPEPKTKS--RTPPRRRS 1690
Score = 35.4 bits (80), Expect = 0.13
Identities = 30/85 (35%), Positives = 36/85 (42%), Gaps = 2/85 (2%)
Query: 400 SVSWSRQTQP-PAALTGRGDAPNRSRNRSSSVDSFRSRCSSASSCSDLEDFSESLSRGGH 458
+V R +P PA R + + S + SSS S S SS+SS S S S S
Sbjct: 2589 AVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2648
Query: 459 RRRGKP-PSPTPWSGSNMKSPPVER 482
KP P P S K PP ER
Sbjct: 2649 PSPAKPGPQALPKPASPKKPPPGER 2673
Score = 35.0 bits (79), Expect = 0.17
Identities = 55/251 (21%), Positives = 87/251 (34%), Gaps = 23/251 (9%)
Query: 243 SRLASEKRELEAQLGRSREEALAGRAARQEAEALRGLVRGLELELRQERGLGHRVAGRRG 302
+R S R + RSR A GR+ + R R + R R R
Sbjct: 590 ARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRS 649
Query: 303 QDCRRLAKELEEAKASERSLRARLKTLTSELALYKRGGRGSRGRGRPARPSPSPTGGRAL 362
+ R + A R+R S + + R RGR R P + R+L
Sbjct: 650 RTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPAR--RGRSRSRTPRRGRSRSRSL 707
Query: 363 RFDPTAFVKAKERKQREIQMKQQQRNRLGSGGSGDGPSVSWSRQTQPPAA--LTGRGDAP 420
R+ R Q+R R GS S + R+++ ++ + +
Sbjct: 708 -----------VRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISS 756
Query: 421 NRSRNRSSSVDSFRSRCSSASSCSDLEDFSESLSR--------GGHRRRGKPPSPTPWSG 472
RSR+ SS +SR S S S + S+ G + + K +P S
Sbjct: 757 RRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSR 816
Query: 473 SNMKSPPVERS 483
S+ PP ++S
Sbjct: 817 SSSSPPPKQKS 827
Score = 34.7 bits (78), Expect = 0.22
Identities = 40/151 (26%), Positives = 56/151 (37%), Gaps = 32/151 (21%)
Query: 341 RGSRGRGRPARPSPSPTG--GRALRFDPTAFVKAKERKQREIQMKQQQRNRLGSGGSGDG 398
R SR R + P T GR+ P +++ R +RE ++R+R GS
Sbjct: 1740 RSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGS------ 1793
Query: 399 PSVSWSRQTQPPAALTGRGDAPNRSRNRSSSVDSFRSRCSSASSCSDLEDFSESLSRGGH 458
S S SR+ Q RSR+RS R S ++ S + SR
Sbjct: 1794 -SQSTSRRRQ-------------RSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRR 1839
Query: 459 RRRGKPP----------SPTPWSGSNMKSPP 479
R PP SP PW S ++ P
Sbjct: 1840 GRSRTPPTSRKRSRSRTSPAPWKRSRSRASP 1870
Score = 32.3 bits (72), Expect = 1.1
Identities = 31/112 (27%), Positives = 37/112 (33%), Gaps = 23/112 (20%)
Query: 404 SRQTQPPAALTGRGDAPNRSRNRSSSVDSFRSRCSSASSCSDLEDFSESLSRGGHR---- 459
S Q P+AL A R + SSS S S SS+SS S S S G
Sbjct: 2512 STGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQ 2571
Query: 460 -------------------RRGKPPSPTPWSGSNMKSPPVERSHHQKSLANS 492
R G+PP PTP S S S ++S
Sbjct: 2572 PEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSS 2623
Score = 32.0 bits (71), Expect = 1.4
Identities = 60/295 (20%), Positives = 97/295 (32%), Gaps = 20/295 (6%)
Query: 210 RSLKEELGRLQGLDGQNTRDTRENEIWHLREQVSRLASEKRELEAQLGRSREEALAGRAA 269
RS R +G G ++R E + R S + RSR + +
Sbjct: 1805 RSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRS 1864
Query: 270 RQEAEAL---RGLVRGLELELRQERGLGHRVAGRRGQDCRRLAKELEEAKAS---ERSLR 323
R A R R + R+ R V+ RR + + + ++AS R R
Sbjct: 1865 RSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSR 1924
Query: 324 ARLKTLTSELALYKRGGRGSRGRGRP-------ARPSPSPTGGRALRFDPTAFVKAKERK 376
+R +T + + R R R +R P R R + + + R
Sbjct: 1925 SRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRS 1984
Query: 377 QREIQMKQQQRNRLGS-----GGSGDGPSVSWSRQTQPPAALT--GRGDAPNRSRNRSSS 429
+ +++ R+R S P +++ P A+ R P R RS S
Sbjct: 1985 RTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRS 2044
Query: 430 VDSFRSRCSSASSCSDLEDFSESLSRGGHRRRGKPPSPTPWSGSNMKSPPVERSH 484
R S S SL+R R + S + S +PP R+H
Sbjct: 2045 RSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNH 2099
Score = 31.6 bits (70), Expect = 1.9
Identities = 54/237 (22%), Positives = 89/237 (37%), Gaps = 32/237 (13%)
Query: 258 RSREEALAGRAARQEAEALR--GLVRGLELELRQERGLGHRVAGRRGQD----CRRLAKE 311
RSR ++ R +R R R + R+ R V RR + RR ++
Sbjct: 1889 RSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRS 1948
Query: 312 LEEAKASERS-------LRARLKTLTSELALYKRGGRGSRGRGRPARPSPSPTGGRALRF 364
RS R R ++ TS + + R S R +R SP R R
Sbjct: 1949 RTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRS 2008
Query: 365 DPTAFVKAKERKQREIQMKQQQRNRLGSGGSGDGPSVSWSR-QTQPPAALTGRGDAPNRS 423
+ + + R + ++++ R+R P + R +++ P A+ R
Sbjct: 2009 RTSPVTRRRSRSRTPPAIRRRSRSRT--------PLLPRKRSRSRSPLAI--------RR 2052
Query: 424 RNRSSSVDSFRSRCSSASSCSDLEDFSESLSRGGHRRRGKPPSPTPWSGSNMKSPPV 480
R+RS + + R + S S + S S S R PP+ SGS ++PPV
Sbjct: 2053 RSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGS--RTPPV 2107
Score = 30.4 bits (67), Expect = 4.2
Identities = 42/189 (22%), Positives = 62/189 (32%), Gaps = 22/189 (11%)
Query: 306 RRLAKELEEAKASERSLRARLKTLTSELALYKRGGRGSRGRGRPARPSPSPTGGRALRFD 365
RR+ + A A R+R T R SR R R GR+
Sbjct: 479 RRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQ 538
Query: 366 PTAFVKAKERKQREIQMKQQQRNRLGSGGSGDGPSVSWSRQTQPPAALTGRGDAPNRSRN 425
+ +++ ++R + + R G S + SR P R P R R+
Sbjct: 539 RPGWSRSRNTQRRG----RSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRS 594
Query: 426 RSSSVDSFRSRCSSASSCSDLEDFSESLSRGGHRRRGKPPSPTPWSGSNMKSPPVERSHH 485
RS + RSR + + RRG+ S TP + PV R
Sbjct: 595 RSRTPTRRRSRSRTPA------------------RRGRSRSRTPARRRSRTRSPVRRRSR 636
Query: 486 QKSLANSGG 494
+S A G
Sbjct: 637 SRSPARRSG 645
Score = 30.4 bits (67), Expect = 4.2
Identities = 39/160 (24%), Positives = 55/160 (34%), Gaps = 28/160 (17%)
Query: 347 GRPARPSPSPTGGRALRFDPTAFVKAKERKQREIQMKQQQRNRLGSGGSGDGPSVSWSRQ 406
GRP P+P+ R+ ++ + + S S S S S
Sbjct: 2593 GRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPA 2652
Query: 407 TQPPAAL----TGRGDAPNRSRNRS--SSVDSFR-SRCSSASSC---------SDLEDFS 450
P AL + + P R+RS +DS R SR S S S + S
Sbjct: 2653 KPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQS 2712
Query: 451 ESLSRGG------------HRRRGKPPSPTPWSGSNMKSP 478
S RG H+RR + PSP P + +SP
Sbjct: 2713 SSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRSP 2752
Score = 30.0 bits (66), Expect = 5.5
Identities = 28/103 (27%), Positives = 42/103 (40%), Gaps = 6/103 (5%)
Query: 396 GDGPSVSWSRQTQPPAALT------GRGDAPNRSRNRSSSVDSFRSRCSSASSCSDLEDF 449
G+ P+ + ++Q AAL + + S + SSS S S SS SS SD E
Sbjct: 2507 GEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGS 2566
Query: 450 SESLSRGGHRRRGKPPSPTPWSGSNMKSPPVERSHHQKSLANS 492
S + +R P+P P PP +K ++S
Sbjct: 2567 SLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSS 2609
Score = 29.6 bits (65), Expect = 7.2
Identities = 33/146 (22%), Positives = 53/146 (36%), Gaps = 9/146 (6%)
Query: 351 RPSPSPTGGRALRFDPTAFVKAKERKQREIQMKQQQRNRLGSGGSGDGPSVSWSRQTQPP 410
+P+P+P R + PT+ ++ R +R+ R+G S SR P
Sbjct: 442 KPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPT 501
Query: 411 AALTGRGDAPNRSRNRS--------SSVDSFRSRCSSASSCSDLEDFSESLSRGGHRRRG 462
R +P R+RS S RSR S + ++ R RRG
Sbjct: 502 KRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRN-TQRRGRSRSARRG 560
Query: 463 KPPSPTPWSGSNMKSPPVERSHHQKS 488
+ S +P + +S R +S
Sbjct: 561 RSHSRSPATRGRSRSRTPARRGRSRS 586
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,641,737
Number of Sequences: 37866
Number of extensions: 1080180
Number of successful extensions: 6746
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 74
Number of HSP's successfully gapped in prelim test: 361
Number of HSP's that attempted gapping in prelim test: 5843
Number of HSP's gapped (non-prelim): 1087
length of query: 531
length of database: 18,247,518
effective HSP length: 107
effective length of query: 424
effective length of database: 14,195,856
effective search space: 6019042944
effective search space used: 6019042944
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.