Guide to the Human Genome
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Search of human proteins with 29029552

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|29029552 cat eye syndrome critical region protein 1 isoform
b [Homo sapiens]
         (270 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|29029552 cat eye syndrome critical region protein 1 isoform b...   554   e-158
gi|29029550 cat eye syndrome critical region protein 1 isoform a...   531   e-151
gi|47078295 adenosine deaminase [Homo sapiens]                         46   3e-05
gi|4502079 adenosine monophosphate deaminase 3 isoform 1A [Homo ...    46   4e-05
gi|70906428 adenosine monophosphate deaminase 3 isoform 1C [Homo...    46   4e-05
gi|70906426 adenosine monophosphate deaminase 3 isoform 1B [Homo...    46   4e-05
gi|4557311 adenosine monophosphate deaminase 1 (isoform M) [Homo...    38   0.011
gi|55925574 adenosine monophosphate deaminase 2 (isoform L) isof...    36   0.031
gi|34147621 adenosine monophosphate deaminase 2 (isoform L) isof...    36   0.031
gi|21264318 adenosine monophosphate deaminase 2 (isoform L) isof...    36   0.031
gi|226693318 adenosine deaminase-like isoform 1 [Homo sapiens]         34   0.15 
gi|71902540 ataxia telangiectasia mutated isoform 1 [Homo sapiens]     28   6.5  
gi|169218268 PREDICTED: similar to Serine-protein kinase ATM, pa...    28   6.5  

>gi|29029552 cat eye syndrome critical region protein 1 isoform b
           [Homo sapiens]
          Length = 270

 Score =  554 bits (1428), Expect = e-158
 Identities = 270/270 (100%), Positives = 270/270 (100%)

Query: 1   MDSLEWNWALVYELSGEHHDEEWSVKTYQEVAQKFVETHPEFIGIKIIYSDHRSKDVAVI 60
           MDSLEWNWALVYELSGEHHDEEWSVKTYQEVAQKFVETHPEFIGIKIIYSDHRSKDVAVI
Sbjct: 1   MDSLEWNWALVYELSGEHHDEEWSVKTYQEVAQKFVETHPEFIGIKIIYSDHRSKDVAVI 60

Query: 61  AESIRMAMGLRIKFPTVVAGFDLVGHEDTGHSLHDYKEALMIPAKDGVKLPYFFHAGETD 120
           AESIRMAMGLRIKFPTVVAGFDLVGHEDTGHSLHDYKEALMIPAKDGVKLPYFFHAGETD
Sbjct: 61  AESIRMAMGLRIKFPTVVAGFDLVGHEDTGHSLHDYKEALMIPAKDGVKLPYFFHAGETD 120

Query: 121 WQGTSIDRNILDALMLNTTRIGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSDL 180
           WQGTSIDRNILDALMLNTTRIGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSDL
Sbjct: 121 WQGTSIDRNILDALMLNTTRIGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSDL 180

Query: 181 RNHPVATLMATGHPMVISSDDPAMFGAKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSIK 240
           RNHPVATLMATGHPMVISSDDPAMFGAKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSIK
Sbjct: 181 RNHPVATLMATGHPMVISSDDPAMFGAKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSIK 240

Query: 241 YSTLLESEKNTFMEIWKKRWDKFIADVATK 270
           YSTLLESEKNTFMEIWKKRWDKFIADVATK
Sbjct: 241 YSTLLESEKNTFMEIWKKRWDKFIADVATK 270


>gi|29029550 cat eye syndrome critical region protein 1 isoform a
           precursor [Homo sapiens]
          Length = 511

 Score =  531 bits (1368), Expect = e-151
 Identities = 260/260 (100%), Positives = 260/260 (100%)

Query: 11  VYELSGEHHDEEWSVKTYQEVAQKFVETHPEFIGIKIIYSDHRSKDVAVIAESIRMAMGL 70
           VYELSGEHHDEEWSVKTYQEVAQKFVETHPEFIGIKIIYSDHRSKDVAVIAESIRMAMGL
Sbjct: 252 VYELSGEHHDEEWSVKTYQEVAQKFVETHPEFIGIKIIYSDHRSKDVAVIAESIRMAMGL 311

Query: 71  RIKFPTVVAGFDLVGHEDTGHSLHDYKEALMIPAKDGVKLPYFFHAGETDWQGTSIDRNI 130
           RIKFPTVVAGFDLVGHEDTGHSLHDYKEALMIPAKDGVKLPYFFHAGETDWQGTSIDRNI
Sbjct: 312 RIKFPTVVAGFDLVGHEDTGHSLHDYKEALMIPAKDGVKLPYFFHAGETDWQGTSIDRNI 371

Query: 131 LDALMLNTTRIGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSDLRNHPVATLMA 190
           LDALMLNTTRIGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSDLRNHPVATLMA
Sbjct: 372 LDALMLNTTRIGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSDLRNHPVATLMA 431

Query: 191 TGHPMVISSDDPAMFGAKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSIKYSTLLESEKN 250
           TGHPMVISSDDPAMFGAKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSIKYSTLLESEKN
Sbjct: 432 TGHPMVISSDDPAMFGAKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSIKYSTLLESEKN 491

Query: 251 TFMEIWKKRWDKFIADVATK 270
           TFMEIWKKRWDKFIADVATK
Sbjct: 492 TFMEIWKKRWDKFIADVATK 511


>gi|47078295 adenosine deaminase [Homo sapiens]
          Length = 363

 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 49/187 (26%), Positives = 83/187 (44%), Gaps = 13/187 (6%)

Query: 76  TVVAGFDLVGHEDTGHS--LHDYKEALMIPAKDGVKLPYFFHAGETDWQGTSIDRNILDA 133
           TVVA  DL G E    S  L  + +A     K G+      HAGE       + +  +D 
Sbjct: 176 TVVA-IDLAGDETIPGSSLLPGHVQAYQEAVKSGIHRTV--HAGEVG--SAEVVKEAVD- 229

Query: 134 LMLNTTRIGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSDLRNHPVATLMATGH 193
            +L T R+GHG+   +  A+     ++++  E+CP S+ +         H V  L     
Sbjct: 230 -ILKTERLGHGYHTLEDQALYNRLRQENMHFEICPWSSYLTGAWKPDTEHAVIRLKNDQA 288

Query: 194 PMVISSDDPAMFGAKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSIKYSTLLESEKNTFM 253
              +++DDP +F +  L  D+      +G  + +    K+L +N+ K S L E EK   +
Sbjct: 289 NYSLNTDDPLIFKST-LDTDYQMTKRDMGFTEEE---FKRLNINAAKSSFLPEDEKRELL 344

Query: 254 EIWKKRW 260
           ++  K +
Sbjct: 345 DLLYKAY 351


>gi|4502079 adenosine monophosphate deaminase 3 isoform 1A [Homo
           sapiens]
          Length = 776

 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 35/124 (28%), Positives = 55/124 (44%), Gaps = 5/124 (4%)

Query: 131 LDALMLNTTRIGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSDLRNHPVATLMA 190
           L +  L    I HG  L K P ++   +   IPI + P+SN  L L  +   +P+   + 
Sbjct: 605 LVSAFLTADNISHGLLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFL--EYSKNPLREFLH 662

Query: 191 TGHPMVISSDDPAMFG-AKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSIKYSTLLESEK 249
            G  + +S+DDP  F   K    + Y +   +   K     L ++A NS+  S L   EK
Sbjct: 663 KGLHVSLSTDDPMQFHYTKEALMEEYAIAAQV--WKLSTCDLCEIARNSVLQSGLSHQEK 720

Query: 250 NTFM 253
             F+
Sbjct: 721 QKFL 724


>gi|70906428 adenosine monophosphate deaminase 3 isoform 1C [Homo
           sapiens]
          Length = 774

 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 35/124 (28%), Positives = 55/124 (44%), Gaps = 5/124 (4%)

Query: 131 LDALMLNTTRIGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSDLRNHPVATLMA 190
           L +  L    I HG  L K P ++   +   IPI + P+SN  L L  +   +P+   + 
Sbjct: 603 LVSAFLTADNISHGLLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFL--EYSKNPLREFLH 660

Query: 191 TGHPMVISSDDPAMFG-AKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSIKYSTLLESEK 249
            G  + +S+DDP  F   K    + Y +   +   K     L ++A NS+  S L   EK
Sbjct: 661 KGLHVSLSTDDPMQFHYTKEALMEEYAIAAQV--WKLSTCDLCEIARNSVLQSGLSHQEK 718

Query: 250 NTFM 253
             F+
Sbjct: 719 QKFL 722


>gi|70906426 adenosine monophosphate deaminase 3 isoform 1B [Homo
           sapiens]
          Length = 767

 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 35/124 (28%), Positives = 55/124 (44%), Gaps = 5/124 (4%)

Query: 131 LDALMLNTTRIGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSDLRNHPVATLMA 190
           L +  L    I HG  L K P ++   +   IPI + P+SN  L L  +   +P+   + 
Sbjct: 596 LVSAFLTADNISHGLLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFL--EYSKNPLREFLH 653

Query: 191 TGHPMVISSDDPAMFG-AKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSIKYSTLLESEK 249
            G  + +S+DDP  F   K    + Y +   +   K     L ++A NS+  S L   EK
Sbjct: 654 KGLHVSLSTDDPMQFHYTKEALMEEYAIAAQV--WKLSTCDLCEIARNSVLQSGLSHQEK 711

Query: 250 NTFM 253
             F+
Sbjct: 712 QKFL 715


>gi|4557311 adenosine monophosphate deaminase 1 (isoform M) [Homo
           sapiens]
          Length = 747

 Score = 37.7 bits (86), Expect = 0.011
 Identities = 30/114 (26%), Positives = 50/114 (43%), Gaps = 5/114 (4%)

Query: 141 IGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSDLRNHPVATLMATGHPMVISSD 200
           I HG  L K P ++   +   IPI + P+SN  L L  +   +P    +  G  + +S+D
Sbjct: 592 ISHGLNLKKSPVLQYLFFLAQIPIAMSPLSNNSLFL--EYAKNPFLDFLQKGLMISLSTD 649

Query: 201 DPAMFG-AKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSIKYSTLLESEKNTFM 253
           DP  F   K    + Y +   +   K     + ++A NS+    +   EK  F+
Sbjct: 650 DPMQFHFTKEPLMEEYAIAAQV--FKLSTCDMCEVARNSVLQCGISHEEKVKFL 701


>gi|55925574 adenosine monophosphate deaminase 2 (isoform L) isoform
           3 [Homo sapiens]
          Length = 760

 Score = 36.2 bits (82), Expect = 0.031
 Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 3/77 (3%)

Query: 129 NILDALMLNTTRIGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSDLRNHPVATL 188
           +++ A ML    I HG  L K P ++   +   I I + P+SN  L L      +P+   
Sbjct: 577 HLVSAFML-AENISHGLLLRKAPVLQYLYYLAQIGIAMSPLSNNSLFL--SYHRNPLPEY 633

Query: 189 MATGHPMVISSDDPAMF 205
           ++ G  + +S+DDP  F
Sbjct: 634 LSRGLMVSLSTDDPLQF 650


>gi|34147621 adenosine monophosphate deaminase 2 (isoform L) isoform
           2 [Homo sapiens]
          Length = 798

 Score = 36.2 bits (82), Expect = 0.031
 Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 3/77 (3%)

Query: 129 NILDALMLNTTRIGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSDLRNHPVATL 188
           +++ A ML    I HG  L K P ++   +   I I + P+SN  L L      +P+   
Sbjct: 615 HLVSAFML-AENISHGLLLRKAPVLQYLYYLAQIGIAMSPLSNNSLFL--SYHRNPLPEY 671

Query: 189 MATGHPMVISSDDPAMF 205
           ++ G  + +S+DDP  F
Sbjct: 672 LSRGLMVSLSTDDPLQF 688


>gi|21264318 adenosine monophosphate deaminase 2 (isoform L) isoform
           1 [Homo sapiens]
          Length = 879

 Score = 36.2 bits (82), Expect = 0.031
 Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 3/77 (3%)

Query: 129 NILDALMLNTTRIGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSDLRNHPVATL 188
           +++ A ML    I HG  L K P ++   +   I I + P+SN  L L      +P+   
Sbjct: 696 HLVSAFML-AENISHGLLLRKAPVLQYLYYLAQIGIAMSPLSNNSLFL--SYHRNPLPEY 752

Query: 189 MATGHPMVISSDDPAMF 205
           ++ G  + +S+DDP  F
Sbjct: 753 LSRGLMVSLSTDDPLQF 769


>gi|226693318 adenosine deaminase-like isoform 1 [Homo sapiens]
          Length = 328

 Score = 33.9 bits (76), Expect = 0.15
 Identities = 33/126 (26%), Positives = 52/126 (41%), Gaps = 18/126 (14%)

Query: 140 RIGHGFALSKHPA----VRTYSWKKDIPIEVCPISNQVLKLVSDLRNHPVATLMATGHPM 195
           RIGHG  L+        +  +  +  IP+E+C  SN   + V     H      +  HP 
Sbjct: 202 RIGHGTFLNSGEGGSLDLVDFVRQHRIPLELCLTSNVKSQTVPSYDQHHFGFWYSIAHPS 261

Query: 196 VISSDDPAMFGAKGLSYDFYEVFMGIGGMKADLRTLKQ-----LAMNSIKYSTLLESEKN 250
           VI +DD  +F A  LS ++         + A+   L Q     L+  SI Y    +S ++
Sbjct: 262 VICTDDKGVF-ATHLSQEYQ--------LAAETFNLTQSQVWDLSYESINYIFASDSTRS 312

Query: 251 TFMEIW 256
              + W
Sbjct: 313 ELRKKW 318


>gi|71902540 ataxia telangiectasia mutated isoform 1 [Homo sapiens]
          Length = 3056

 Score = 28.5 bits (62), Expect = 6.5
 Identities = 12/33 (36%), Positives = 20/33 (60%)

Query: 228 LRTLKQLAMNSIKYSTLLESEKNTFMEIWKKRW 260
           LR L ++A+   K S L  S+K+  +++W K W
Sbjct: 456 LRCLTEVALCQDKRSNLESSQKSDLLKLWNKIW 488


>gi|169218268 PREDICTED: similar to Serine-protein kinase ATM,
           partial [Homo sapiens]
          Length = 2934

 Score = 28.5 bits (62), Expect = 6.5
 Identities = 12/33 (36%), Positives = 20/33 (60%)

Query: 228 LRTLKQLAMNSIKYSTLLESEKNTFMEIWKKRW 260
           LR L ++A+   K S L  S+K+  +++W K W
Sbjct: 334 LRCLTEVALCQDKRSNLESSQKSDLLKLWNKIW 366


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.135    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,520,598
Number of Sequences: 37866
Number of extensions: 367212
Number of successful extensions: 758
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 748
Number of HSP's gapped (non-prelim): 13
length of query: 270
length of database: 18,247,518
effective HSP length: 101
effective length of query: 169
effective length of database: 14,423,052
effective search space: 2437495788
effective search space used: 2437495788
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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