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Search of human proteins with 28872814
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|28872814 semaphorin 4G [Homo sapiens]
(843 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|28872814 semaphorin 4G [Homo sapiens] 1719 0.0
gi|157388902 semaphorin 4C [Homo sapiens] 528 e-149
gi|214010218 semaphorin 4D isoform 1 [Homo sapiens] 425 e-118
gi|214010220 semaphorin 4D isoform 2 [Homo sapiens] 411 e-114
gi|39777610 semaphorin 4B precursor [Homo sapiens] 394 e-109
gi|39777608 semaphorin 4B precursor [Homo sapiens] 394 e-109
gi|19923279 semaphorin W [Homo sapiens] 360 4e-99
gi|21361914 semaphorin B [Homo sapiens] 341 2e-93
gi|5174673 semaphorin 3A precursor [Homo sapiens] 339 7e-93
gi|41406086 semaphorin 3D [Homo sapiens] 327 2e-89
gi|4759092 semaphorin 3B isoform 1 precursor [Homo sapiens] 320 5e-87
gi|54607089 semaphorin 3B isoform 2 precursor [Homo sapiens] 319 8e-87
gi|9910362 semaphorin sem2 [Homo sapiens] 315 9e-86
gi|188497703 semaphorin 3F [Homo sapiens] 299 8e-81
gi|6912650 semaphorin 3E [Homo sapiens] 282 1e-75
gi|5454048 semaphorin 3C [Homo sapiens] 272 1e-72
gi|11991660 sema domain, transmembrane domain (TM), and cytoplas... 228 2e-59
gi|24234729 semaphorin 6D isoform 1 precursor [Homo sapiens] 221 2e-57
gi|24234744 semaphorin 6D isoform 5 precursor [Homo sapiens] 221 2e-57
gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens] 221 2e-57
gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens] 221 2e-57
gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens] 221 2e-57
gi|19718780 semaphorin 6B precursor [Homo sapiens] 212 1e-54
gi|16306552 semaphorin Y [Homo sapiens] 205 2e-52
gi|91982767 semaphorin 5B isoform 1 [Homo sapiens] 201 2e-51
gi|147904700 semaphorin 5A [Homo sapiens] 197 3e-50
gi|24234732 semaphorin 6D isoform 6 precursor [Homo sapiens] 178 2e-44
gi|4504237 semaphorin 7A isoform 1 preproprotein [Homo sapiens] 173 5e-43
gi|225637520 semaphorin 7A isoform 2 preproprotein [Homo sapiens] 170 4e-42
gi|225637524 semaphorin 7A isoform 3 [Homo sapiens] 148 2e-35
>gi|28872814 semaphorin 4G [Homo sapiens]
Length = 843
Score = 1719 bits (4452), Expect = 0.0
Identities = 843/843 (100%), Positives = 843/843 (100%)
Query: 1 MWGRLWPLLLSILTATAVPGPSLRRPSRELDATPRMTIPYEELSGTRHFKGQAQNYSTLL 60
MWGRLWPLLLSILTATAVPGPSLRRPSRELDATPRMTIPYEELSGTRHFKGQAQNYSTLL
Sbjct: 1 MWGRLWPLLLSILTATAVPGPSLRRPSRELDATPRMTIPYEELSGTRHFKGQAQNYSTLL 60
Query: 61 LEEASARLLVGARGALFSLSANDIGDGAHKEIHWEASPEMQSKCHQKGKNNQTECFNHVR 120
LEEASARLLVGARGALFSLSANDIGDGAHKEIHWEASPEMQSKCHQKGKNNQTECFNHVR
Sbjct: 61 LEEASARLLVGARGALFSLSANDIGDGAHKEIHWEASPEMQSKCHQKGKNNQTECFNHVR 120
Query: 121 FLQRLNSTHLYACGTHAFQPLCAAIDAEAFTLPTSFEEGKEKCPYDPARGFTGLIIDGGL 180
FLQRLNSTHLYACGTHAFQPLCAAIDAEAFTLPTSFEEGKEKCPYDPARGFTGLIIDGGL
Sbjct: 121 FLQRLNSTHLYACGTHAFQPLCAAIDAEAFTLPTSFEEGKEKCPYDPARGFTGLIIDGGL 180
Query: 181 YTATRYEFRSIPDIRRSRHPHSLRTEETPMHWLNDAEFVFSVLVRESKASAVGDDDKVYY 240
YTATRYEFRSIPDIRRSRHPHSLRTEETPMHWLNDAEFVFSVLVRESKASAVGDDDKVYY
Sbjct: 181 YTATRYEFRSIPDIRRSRHPHSLRTEETPMHWLNDAEFVFSVLVRESKASAVGDDDKVYY 240
Query: 241 FFTERATEEGSGSFTQSRSSHRVARVARVCKGDLGGKKILQKKWTSFLKARLICHIPLYE 300
FFTERATEEGSGSFTQSRSSHRVARVARVCKGDLGGKKILQKKWTSFLKARLICHIPLYE
Sbjct: 241 FFTERATEEGSGSFTQSRSSHRVARVARVCKGDLGGKKILQKKWTSFLKARLICHIPLYE 300
Query: 301 TLRGVCSLDAETSSRTHFYAAFTLSTQWKTLEASAICRYDLAEIQAVFAGPYMEYQDGSR 360
TLRGVCSLDAETSSRTHFYAAFTLSTQWKTLEASAICRYDLAEIQAVFAGPYMEYQDGSR
Sbjct: 301 TLRGVCSLDAETSSRTHFYAAFTLSTQWKTLEASAICRYDLAEIQAVFAGPYMEYQDGSR 360
Query: 361 RWGRYEGGVPEPRPGSCITDSLRSQGYNSSQDLPSLVLDFVKLHPLMARPVVPTRGRPLL 420
RWGRYEGGVPEPRPGSCITDSLRSQGYNSSQDLPSLVLDFVKLHPLMARPVVPTRGRPLL
Sbjct: 361 RWGRYEGGVPEPRPGSCITDSLRSQGYNSSQDLPSLVLDFVKLHPLMARPVVPTRGRPLL 420
Query: 421 LKRNIRYTHLTGTPVTTPAGPTYDLLFLGTADGWIHKAVVLGSGMHIIEETQVFRESQSV 480
LKRNIRYTHLTGTPVTTPAGPTYDLLFLGTADGWIHKAVVLGSGMHIIEETQVFRESQSV
Sbjct: 421 LKRNIRYTHLTGTPVTTPAGPTYDLLFLGTADGWIHKAVVLGSGMHIIEETQVFRESQSV 480
Query: 481 ENLVISLLQHSLYVGAPSGVIQLPLSSCSRYRSCYDCILARDPYCGWDPGTHACAAATTI 540
ENLVISLLQHSLYVGAPSGVIQLPLSSCSRYRSCYDCILARDPYCGWDPGTHACAAATTI
Sbjct: 481 ENLVISLLQHSLYVGAPSGVIQLPLSSCSRYRSCYDCILARDPYCGWDPGTHACAAATTI 540
Query: 541 ANRSQGSRTALIQDIERGNRGCESSRDTGPPPPLKTRSVLRGDDVLLPCDQPSNLARALW 600
ANRSQGSRTALIQDIERGNRGCESSRDTGPPPPLKTRSVLRGDDVLLPCDQPSNLARALW
Sbjct: 541 ANRSQGSRTALIQDIERGNRGCESSRDTGPPPPLKTRSVLRGDDVLLPCDQPSNLARALW 600
Query: 601 LLNGSMGLSDGQGGYRVGVDGLLVTDAQPEHSGNYGCYAEENGLRTLLASYSLTVRPATP 660
LLNGSMGLSDGQGGYRVGVDGLLVTDAQPEHSGNYGCYAEENGLRTLLASYSLTVRPATP
Sbjct: 601 LLNGSMGLSDGQGGYRVGVDGLLVTDAQPEHSGNYGCYAEENGLRTLLASYSLTVRPATP 660
Query: 661 APAPKAPATPGAQLAPDVRLLYVLAIAALGGLCLILASSLLYVACLREGRRGRRRKYSLG 720
APAPKAPATPGAQLAPDVRLLYVLAIAALGGLCLILASSLLYVACLREGRRGRRRKYSLG
Sbjct: 661 APAPKAPATPGAQLAPDVRLLYVLAIAALGGLCLILASSLLYVACLREGRRGRRRKYSLG 720
Query: 721 RASRAGGSAVQLQTVSGQCPGEEDEGDDEGAGGLEGSCLQIIPGEGAPAPPPPPPPPPPA 780
RASRAGGSAVQLQTVSGQCPGEEDEGDDEGAGGLEGSCLQIIPGEGAPAPPPPPPPPPPA
Sbjct: 721 RASRAGGSAVQLQTVSGQCPGEEDEGDDEGAGGLEGSCLQIIPGEGAPAPPPPPPPPPPA 780
Query: 781 ELTNGLVALPSRLRRMNGNSYVLLRQSNNGVPAGPCSFAEELSRILEKRKHTQLVEQLDE 840
ELTNGLVALPSRLRRMNGNSYVLLRQSNNGVPAGPCSFAEELSRILEKRKHTQLVEQLDE
Sbjct: 781 ELTNGLVALPSRLRRMNGNSYVLLRQSNNGVPAGPCSFAEELSRILEKRKHTQLVEQLDE 840
Query: 841 SSV 843
SSV
Sbjct: 841 SSV 843
>gi|157388902 semaphorin 4C [Homo sapiens]
Length = 833
Score = 528 bits (1359), Expect = e-149
Identities = 337/829 (40%), Positives = 446/829 (53%), Gaps = 68/829 (8%)
Query: 34 PRMTIPYEELSGT--RHFKGQAQNYSTLLLEEASARLLVGARGALFSLSANDIG-DGAHK 90
PR T+ EL+ R + Q++ TL L E + L VGAR ALF+ S + GA
Sbjct: 29 PRKTVSSGELATVVRRFSQTGIQDFLTLTLTEPTGLLYVGAREALFAFSMEALELQGA-- 86
Query: 91 EIHWEASPEMQSKCHQKGKNNQTECFNHVRFLQRLNSTHLYACGTHAFQPLCAAIDAEAF 150
I WEA E +++C QKGKNNQTECFN +RFLQ N++HLY CGT+AFQP C ++ F
Sbjct: 87 -ISWEAPVEKKTECIQKGKNNQTECFNFIRFLQPYNASHLYVCGTYAFQPKCTYVNMLTF 145
Query: 151 TLPTS-FEEGKEKCPYDPARGFTGLIIDGGLYTATRYEFRSI-PDIRRSRHPHSLRTEET 208
TL FE+GK KCPYDPA+G GL++DG LY+AT F P I R+ PH E
Sbjct: 146 TLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSATLNNFLGTEPIILRNMGPHHSMKTEY 205
Query: 209 PMHWLNDAEFVFSVLVRESKASAVGDDDKVYYFFTERATEEGSGSFTQSRSSHRVARVAR 268
WLN+ FV S V ES S GDDDKVY+FF ERA E + + VARVAR
Sbjct: 206 LAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFFFRERAVE------SDCYAEQVVARVAR 259
Query: 269 VCKGDLGGKKILQKKWTSFLKARLICHIP----LYETLRGVCSLDAETSSRTHFYAAFTL 324
VCKGD+GG + LQ+KWT+FLKARL C P + L+ + +L + T F+ F
Sbjct: 260 VCKGDMGGARTLQRKWTTFLKARLACSAPNWQLYFNQLQAMHTLQDTSWHNTTFFGVF-- 317
Query: 325 STQWKTLEASAICRYDLAEIQAVFAGPYMEYQDGSRRWGRYEGGVPEPRPGSCITDSLRS 384
QW + SAIC Y L EIQ VF GPY EY + +++W RY VP PRPGSCI + R
Sbjct: 318 QAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWDRYTDPVPSPRPGSCINNWHRR 377
Query: 385 QGYNSSQDLPSLVLDFVKLHPLMARPVVPTRGRPLLLKRNIRYTHLTGTPVTTPAGPTYD 444
GY SS +LP +L+FVK HPLM V P RPLL+K+ +THL VT G TY
Sbjct: 378 HGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVKKGTNFTHLVADRVTGLDGATYT 437
Query: 445 LLFLGTADGWIHKAVVLGSGMHIIEETQVFRESQSVENLVISLLQHSLYVGAPSGVIQLP 504
+LF+GT DGW+ KAV LG +H+IEE Q+F + + + +LV+S + L+ G+ S ++QLP
Sbjct: 438 VLFIGTGDGWLLKAVSLGPWVHLIEELQLF-DQEPMRSLVLSQSKKLLFAGSRSQLVQLP 496
Query: 505 LSSCSRYRSCYDCILARDPYCGWDPGTHACAAATTIANRSQGSRTALIQDI----ERGNR 560
++ C +YRSC DC+LARDPYC W T C A S + LIQ + G
Sbjct: 497 VADCMKYRSCADCVLARDPYCAWSVNTSRCVAV------GGHSGSLLIQHVMTSDTSGIC 550
Query: 561 GCESSRDTGPPPPLKTRSVLRGDDVLLPCDQPSNLARALWLLNGSMGLSDGQGG--YRVG 618
S+ P P K +V+ G D++LPC SNLA A W G ++ G Y
Sbjct: 551 NLRGSKKVRPTP--KNITVVAGTDLVLPCHLSSNLAHARWTFGGRDLPAEQPGSFLYDAR 608
Query: 619 VDGLLVTDAQPEHSGNYGCYAEENGLRTLLASYSLTVRPATPAPAPKAPATPGAQLAPDV 678
+ L+V AQP H+G Y C++EE G R Y + V A P+ +A A P L
Sbjct: 609 LQALVVMAAQPRHAGAYHCFSEEQGARLAAEGYLVAV-VAGPSVTLEARA-PLENLG--- 663
Query: 679 RLLYVLAIAALGGLCLILASSLLYVACLREGRRGRRRKYSLGRASRAGGSAV-------- 730
L LA+ ALG +CL+L LL V LR RR + L + ++A +
Sbjct: 664 --LVWLAVVALGAVCLVL---LLLVLSLR-----RRLREELEKGAKATERTLVYPLELPK 713
Query: 731 -QLQTVSGQCPGEEDEGDDEGAGGLEGSCLQIIPGEGAPAPPPPPPPPPPAELTNGLVAL 789
CP +++ D L+I+PG P PP PPP + +
Sbjct: 714 EPTSPPFRPCPEPDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPG-IPGQPLPS 772
Query: 790 PSRL-----RRMNGNSYVLLR---QSNNGVPAGPCSFAEELSRILEKRK 830
P+RL R N N YV L+ + G+ A+EL R L++R+
Sbjct: 773 PTRLHLGGGRNSNANGYVRLQLGGEDRGGLGHPLPELADELRRKLQQRQ 821
>gi|214010218 semaphorin 4D isoform 1 [Homo sapiens]
Length = 862
Score = 425 bits (1092), Expect = e-118
Identities = 252/663 (38%), Positives = 369/663 (55%), Gaps = 36/663 (5%)
Query: 34 PRMTIPYEELSGTRHFKGQAQNYSTLLLEEASARLLVGARGALFSLSANDIGDGAHKEIH 93
PR+T + E+ + + NYS LLL E L +GAR A+F+++A +I + H E++
Sbjct: 28 PRITWEHREVHLVQFHEPDIYNYSALLLSEDKDTLYIGAREAVFAVNALNISEKQH-EVY 86
Query: 94 WEASPEMQSKCHQKGKNNQTECFNHVRFLQRLNSTHLYACGTHAFQPLCAAIDAEAFTLP 153
W+ S + ++KC +KGK+ QTEC N++R LQ L++T LY CGT+AFQP C ++ +F
Sbjct: 87 WKVSEDKKAKCAEKGKSKQTECLNYIRVLQPLSATSLYVCGTNAFQPACDHLNLTSFKFL 146
Query: 154 TSFEEGKEKCPYDPARGFTGLIIDGGLYTATRYEF-RSIPDIRRSRHPHSLRTEETPMHW 212
E+GK +CP+DPA +T +++DG LY+ T Y F S P I R+ LRTE + W
Sbjct: 147 GKNEDGKGRCPFDPAHSYTSVMVDGELYSGTSYNFLGSEPIISRNSSHSPLRTEYA-IPW 205
Query: 213 LNDAEFVFSVLVRESKASAVGDDDKVYYFFTERATEEGSGSFTQSRSSHRVARVARVCKG 272
LN+ FVF+ ++R+S S G+DD+VY+FFTE + E + + R+ARVCKG
Sbjct: 206 LNEPSFVFADVIRKSPDSPDGEDDRVYFFFTEVSVE------YEFVFRVLIPRIARVCKG 259
Query: 273 DLGGKKILQKKWTSFLKARLICHIP----LYETLRGVCSLDAETSSRTHFYAAFTLSTQW 328
D GG + LQKKWTSFLKARLIC P ++ LR V L + FYA FT Q
Sbjct: 260 DQGGLRTLQKKWTSFLKARLICSRPDSGLVFNVLRDVFVLRSPGLKVPVFYALFT--PQL 317
Query: 329 KTLEASAICRYDLAEIQAVFA-GPYME---YQDGSRRWGRYEGGVPEPRPGSCITDSLRS 384
+ SA+C Y+L+ + VF+ G YM+ + +W RY G VP+PRPG+CI R+
Sbjct: 318 NNVGLSAVCAYNLSTAEEVFSHGKYMQSTTVEQSHTKWVRYNGPVPKPRPGACIDSEARA 377
Query: 385 QGYNSSQDLPSLVLDFVKLHPLMARPVVPTRGRPLLLKRNIRYTHLTGTPVTTPAGPTYD 444
Y SS +LP L FVK HPLM V P RP L+K+++ YT + G YD
Sbjct: 378 ANYTSSLNLPDKTLQFVKDHPLMDDSVTPIDNRPRLIKKDVNYTQIVVDRTQALDGTVYD 437
Query: 445 LLFLGTADGWIHKAVVLGSGMHIIEETQVFRESQSVENLVISLLQHS--LYVGAPSGVIQ 502
++F+ T G +HKA+ L +HIIEETQ+F++ + V+ L++S + + +Y G+ SGV+Q
Sbjct: 438 VMFVSTDRGALHKAISLEHAVHIIEETQLFQDFEPVQTLLLSSKKGNRFVYAGSNSGVVQ 497
Query: 503 LPLSSCSRYRSCYDCILARDPYCGWDPGTHACAAATTIANRSQGSRTALIQDIERGNRGC 562
PL+ C ++ +C DC+LARDPYC W P T C A + S+G LIQ++ G+
Sbjct: 498 APLAFCGKHGTCEDCVLARDPYCAWSPPTATCVALHQTESPSRG----LIQEMS-GDASV 552
Query: 563 ESSRDTGPPPPLKTRSVLRGDDVLLPCDQPSNLARALWLLNGSMGLSDGQGGYRVGVDGL 622
+ G + G L C Q SNLAR W + ++ +G L
Sbjct: 553 CPDKSKG---SYRQHFFKHGGTAELKCSQKSNLARVFWKFQNGVLKAESPKYGLMGRKNL 609
Query: 623 LVTDAQPEHSGNYGCYAEE----NGLRTLLASYSLTVR---PATPAPAPKAPATPGAQLA 675
L+ + SG Y C +EE + ++A + L V+ AP T G+++A
Sbjct: 610 LIFNLSEGDSGVYQCLSEERVKNKTVFQVVAKHVLEVKVVPKPVVAPTLSVVQTEGSRIA 669
Query: 676 PDV 678
V
Sbjct: 670 TKV 672
>gi|214010220 semaphorin 4D isoform 2 [Homo sapiens]
Length = 738
Score = 411 bits (1057), Expect = e-114
Identities = 227/551 (41%), Positives = 327/551 (59%), Gaps = 25/551 (4%)
Query: 34 PRMTIPYEELSGTRHFKGQAQNYSTLLLEEASARLLVGARGALFSLSANDIGDGAHKEIH 93
PR+T + E+ + + NYS LLL E L +GAR A+F+++A +I + H E++
Sbjct: 28 PRITWEHREVHLVQFHEPDIYNYSALLLSEDKDTLYIGAREAVFAVNALNISEKQH-EVY 86
Query: 94 WEASPEMQSKCHQKGKNNQTECFNHVRFLQRLNSTHLYACGTHAFQPLCAAIDAEAFTLP 153
W+ S + ++KC +KGK+ QTEC N++R LQ L++T LY CGT+AFQP C ++ +F
Sbjct: 87 WKVSEDKKAKCAEKGKSKQTECLNYIRVLQPLSATSLYVCGTNAFQPACDHLNLTSFKFL 146
Query: 154 TSFEEGKEKCPYDPARGFTGLIIDGGLYTATRYEF-RSIPDIRRSRHPHSLRTEETPMHW 212
E+GK +CP+DPA +T +++DG LY+ T Y F S P I R+ LRTE + W
Sbjct: 147 GKNEDGKGRCPFDPAHSYTSVMVDGELYSGTSYNFLGSEPIISRNSSHSPLRTEYA-IPW 205
Query: 213 LNDAEFVFSVLVRESKASAVGDDDKVYYFFTERATEEGSGSFTQSRSSHRVARVARVCKG 272
LN+ FVF+ ++R+S S G+DD+VY+FFTE + E + + R+ARVCKG
Sbjct: 206 LNEPSFVFADVIRKSPDSPDGEDDRVYFFFTEVSVE------YEFVFRVLIPRIARVCKG 259
Query: 273 DLGGKKILQKKWTSFLKARLICHIP----LYETLRGVCSLDAETSSRTHFYAAFTLSTQW 328
D GG + LQKKWTSFLKARLIC P ++ LR V L + FYA FT Q
Sbjct: 260 DQGGLRTLQKKWTSFLKARLICSRPDSGLVFNVLRDVFVLRSPGLKVPVFYALFT--PQL 317
Query: 329 KTLEASAICRYDLAEIQAVFA-GPYME---YQDGSRRWGRYEGGVPEPRPGSCITDSLRS 384
+ SA+C Y+L+ + VF+ G YM+ + +W RY G VP+PRPG+CI R+
Sbjct: 318 NNVGLSAVCAYNLSTAEEVFSHGKYMQSTTVEQSHTKWVRYNGPVPKPRPGACIDSEARA 377
Query: 385 QGYNSSQDLPSLVLDFVKLHPLMARPVVPTRGRPLLLKRNIRYTHLTGTPVTTPAGPTYD 444
Y SS +LP L FVK HPLM V P RP L+K+++ YT + G YD
Sbjct: 378 ANYTSSLNLPDKTLQFVKDHPLMDDSVTPIDNRPRLIKKDVNYTQIVVDRTQALDGTVYD 437
Query: 445 LLFLGTADGWIHKAVVLGSGMHIIEETQVFRESQSVENLVISLLQHS--LYVGAPSGVIQ 502
++F+ T G +HKA+ L +HIIEETQ+F++ + V+ L++S + + +Y G+ SGV+Q
Sbjct: 438 VMFVSTDRGALHKAISLEHAVHIIEETQLFQDFEPVQTLLLSSKKGNRFVYAGSNSGVVQ 497
Query: 503 LPLSSCSRYRSCYDCILARDPYCGWDPGTHACAAATTIANRSQGSRTALIQDIERGNRGC 562
PL+ C ++ +C DC+LARDPYC W P T C A + S+G LIQ++ C
Sbjct: 498 APLAFCGKHGTCEDCVLARDPYCAWSPPTATCVALHQTESPSRG----LIQEMSGDASVC 553
Query: 563 ESSRDTGPPPP 573
+S PPP
Sbjct: 554 PASSPKPLPPP 564
>gi|39777610 semaphorin 4B precursor [Homo sapiens]
Length = 837
Score = 394 bits (1013), Expect = e-109
Identities = 262/681 (38%), Positives = 363/681 (53%), Gaps = 57/681 (8%)
Query: 2 WGRLWP----LLLSILTATAVPGPSLRRPSRELDATPRMTIPY--EELSGTRHFKGQAQN 55
WG L P LLL +L P P P+ L +PR+++P EE R N
Sbjct: 16 WGALPPRPPLLLLLLLLLLLQPPP----PTWAL--SPRISLPLGSEERPFLRFEAEHISN 69
Query: 56 YSTLLLEEASARLLVGARGALFSLSAN--DIGDGAHKEIHWEASPEMQSKCHQKGKNNQT 113
Y+ LLL L VGAR ALF+LS+N + G ++E+ W A E + +C KGK+ Q
Sbjct: 70 YTALLLSRDGRTLYVGAREALFALSSNLSFLPGGEYQELLWGADAEKKQQCSFKGKDPQR 129
Query: 114 ECFNHVRFLQRLNSTHLYACGTHAFQPLCAAIDAEAFTLPTS------FEEGKEKCPYDP 167
+C N+++ L L+ +HL+ CGT AF P+C I+ E FTL E+GK +CP+DP
Sbjct: 130 DCQNYIKILLPLSGSHLFTCGTAAFSPMCTYINMENFTLARDEKGNVLLEDGKGRCPFDP 189
Query: 168 ARGFTGLIIDGGLYTATRYEFR-SIPDIRRSRHPHSLRTEETPMHWLNDAEFVFSVLVRE 226
T L++DG LYT T F+ + P I RS+ +TE + ++WL D FV S + E
Sbjct: 190 NFKSTALVVDGELYTGTVSSFQGNDPAISRSQSLRPTKTESS-LNWLQDPAFVASAYIPE 248
Query: 227 SKASAVGDDDKVYYFFTERATEEGSGSFTQSRSSHRVARVARVCKGDLGGKKILQKKWTS 286
S S GDDDK+Y+FF+E +G + + V+R+AR+CKGD GG+++LQ++WTS
Sbjct: 249 SLGSLQGDDDKIYFFFSE------TGQEFEFFENTIVSRIARICKGDEGGERVLQQRWTS 302
Query: 287 FLKARLICHIP----LYETLRGVCSLDAETSS--RTHFYAAFTLSTQWKTLEASAICRYD 340
FLKA+L+C P + L+ V +L T FY FT T E SA+C +
Sbjct: 303 FLKAQLLCSRPDDGFPFNVLQDVFTLSPSPQDWRDTLFYGVFTSQWHRGTTEGSAVCVFT 362
Query: 341 LAEIQAVFAGPYMEYQDGSRRWGRYEGGVPEPRPGSCITDSLRSQGYNSSQDLPSLVLDF 400
+ ++Q VF+G Y E +++W VP PRPG+CIT+S R + NSS LP VL+F
Sbjct: 363 MKDVQRVFSGLYKEVNRETQQWYTVTHPVPTPRPGACITNSARERKINSSLQLPDRVLNF 422
Query: 401 VKLHPLMARPVVPTRGRPLLLKRNIRYTHLTGTPVTTPAGPTYDLLFLGTADGWIHKAVV 460
+K H LM V R R LLL+ RY + V TYD+LFLGT DG +HKAV
Sbjct: 423 LKDHFLMDGQV---RSRMLLLQPQARYQRVAVHRVPG-LHHTYDVLFLGTGDGRLHKAVS 478
Query: 461 LGSGMHIIEETQVFRESQSVENLVISLLQHSLYVGAPSGVIQLPLSSCSRYRSCYDCILA 520
+G +HIIEE Q+F Q V+NL++ + LY + SGV+Q+P+++CS YRSC DC+LA
Sbjct: 479 VGPRVHIIEELQIFSSGQPVQNLLLDTHRGLLYAASHSGVVQVPMANCSLYRSCGDCLLA 538
Query: 521 RDPYCGWDPGT--HACAAATTIANRSQGSRTALIQDIERGNRG--CESSRDTGP------ 570
RDPYC W + H +A R IQDIE + C +S P
Sbjct: 539 RDPYCAWSGSSCKHVSLYQPQLATR------PWIQDIEGASAKDLCSASSVVSPSFVPTG 592
Query: 571 PPPLKTRSVLRGDDVLLPCDQPSNLARALWLLNGSMGLSDGQGGYRVGVDGLLVTDAQPE 630
P + L C SNLA LWL NG+ + D LLV Q
Sbjct: 593 EKPCEQVQFQPNTVNTLACPLLSNLATRLWLRNGAPVNASASCHVLPTGDLLLVGTQQ-- 650
Query: 631 HSGNYGCYAEENGLRTLLASY 651
G + C++ E G + L+ASY
Sbjct: 651 -LGEFQCWSLEEGFQQLVASY 670
>gi|39777608 semaphorin 4B precursor [Homo sapiens]
Length = 837
Score = 394 bits (1013), Expect = e-109
Identities = 262/681 (38%), Positives = 363/681 (53%), Gaps = 57/681 (8%)
Query: 2 WGRLWP----LLLSILTATAVPGPSLRRPSRELDATPRMTIPY--EELSGTRHFKGQAQN 55
WG L P LLL +L P P P+ L +PR+++P EE R N
Sbjct: 16 WGALPPRPPLLLLLLLLLLLQPPP----PTWAL--SPRISLPLGSEERPFLRFEAEHISN 69
Query: 56 YSTLLLEEASARLLVGARGALFSLSAN--DIGDGAHKEIHWEASPEMQSKCHQKGKNNQT 113
Y+ LLL L VGAR ALF+LS+N + G ++E+ W A E + +C KGK+ Q
Sbjct: 70 YTALLLSRDGRTLYVGAREALFALSSNLSFLPGGEYQELLWGADAEKKQQCSFKGKDPQR 129
Query: 114 ECFNHVRFLQRLNSTHLYACGTHAFQPLCAAIDAEAFTLPTS------FEEGKEKCPYDP 167
+C N+++ L L+ +HL+ CGT AF P+C I+ E FTL E+GK +CP+DP
Sbjct: 130 DCQNYIKILLPLSGSHLFTCGTAAFSPMCTYINMENFTLARDEKGNVLLEDGKGRCPFDP 189
Query: 168 ARGFTGLIIDGGLYTATRYEFR-SIPDIRRSRHPHSLRTEETPMHWLNDAEFVFSVLVRE 226
T L++DG LYT T F+ + P I RS+ +TE + ++WL D FV S + E
Sbjct: 190 NFKSTALVVDGELYTGTVSSFQGNDPAISRSQSLRPTKTESS-LNWLQDPAFVASAYIPE 248
Query: 227 SKASAVGDDDKVYYFFTERATEEGSGSFTQSRSSHRVARVARVCKGDLGGKKILQKKWTS 286
S S GDDDK+Y+FF+E +G + + V+R+AR+CKGD GG+++LQ++WTS
Sbjct: 249 SLGSLQGDDDKIYFFFSE------TGQEFEFFENTIVSRIARICKGDEGGERVLQQRWTS 302
Query: 287 FLKARLICHIP----LYETLRGVCSLDAETSS--RTHFYAAFTLSTQWKTLEASAICRYD 340
FLKA+L+C P + L+ V +L T FY FT T E SA+C +
Sbjct: 303 FLKAQLLCSRPDDGFPFNVLQDVFTLSPSPQDWRDTLFYGVFTSQWHRGTTEGSAVCVFT 362
Query: 341 LAEIQAVFAGPYMEYQDGSRRWGRYEGGVPEPRPGSCITDSLRSQGYNSSQDLPSLVLDF 400
+ ++Q VF+G Y E +++W VP PRPG+CIT+S R + NSS LP VL+F
Sbjct: 363 MKDVQRVFSGLYKEVNRETQQWYTVTHPVPTPRPGACITNSARERKINSSLQLPDRVLNF 422
Query: 401 VKLHPLMARPVVPTRGRPLLLKRNIRYTHLTGTPVTTPAGPTYDLLFLGTADGWIHKAVV 460
+K H LM V R R LLL+ RY + V TYD+LFLGT DG +HKAV
Sbjct: 423 LKDHFLMDGQV---RSRMLLLQPQARYQRVAVHRVPG-LHHTYDVLFLGTGDGRLHKAVS 478
Query: 461 LGSGMHIIEETQVFRESQSVENLVISLLQHSLYVGAPSGVIQLPLSSCSRYRSCYDCILA 520
+G +HIIEE Q+F Q V+NL++ + LY + SGV+Q+P+++CS YRSC DC+LA
Sbjct: 479 VGPRVHIIEELQIFSSGQPVQNLLLDTHRGLLYAASHSGVVQVPMANCSLYRSCGDCLLA 538
Query: 521 RDPYCGWDPGT--HACAAATTIANRSQGSRTALIQDIERGNRG--CESSRDTGP------ 570
RDPYC W + H +A R IQDIE + C +S P
Sbjct: 539 RDPYCAWSGSSCKHVSLYQPQLATR------PWIQDIEGASAKDLCSASSVVSPSFVPTG 592
Query: 571 PPPLKTRSVLRGDDVLLPCDQPSNLARALWLLNGSMGLSDGQGGYRVGVDGLLVTDAQPE 630
P + L C SNLA LWL NG+ + D LLV Q
Sbjct: 593 EKPCEQVQFQPNTVNTLACPLLSNLATRLWLRNGAPVNASASCHVLPTGDLLLVGTQQ-- 650
Query: 631 HSGNYGCYAEENGLRTLLASY 651
G + C++ E G + L+ASY
Sbjct: 651 -LGEFQCWSLEEGFQQLVASY 670
>gi|19923279 semaphorin W [Homo sapiens]
Length = 770
Score = 360 bits (923), Expect = 4e-99
Identities = 254/722 (35%), Positives = 364/722 (50%), Gaps = 66/722 (9%)
Query: 8 LLLSILTATAVPGPSLRRPSRELDATPRMTIPYEELSG--TRHFKGQAQNYSTLLLEEAS 65
LLL++L+ GP R R + PR ++P E TR NYS LL++ AS
Sbjct: 23 LLLAVLS-----GPVSGRVPRSV---PRTSLPISEADSCLTRFAVPHTYNYSVLLVDPAS 74
Query: 66 ARLLVGARGALFSLSANDIGDGAHKEIHWEASPEMQSKCHQKGKNNQTECFNHVRFLQRL 125
L VGAR +F+LS G+ + I W + C +KGK + EC N V+ L
Sbjct: 75 HTLYVGARDTIFALSLPFSGERPRR-IDWMVPEAHRQNCRKKGKK-EDECHNFVQILAIA 132
Query: 126 NSTHLYACGTHAFQPLCAAIDAEAFTLPTSFEEGKEKCPYDPARGFTGLIIDGGLYTATR 185
N++HL CGT AF P C ID F E G+ KCP++PA+ ++ G LY AT
Sbjct: 133 NASHLLTCGTFAFDPKCGVIDVSRFQQVERLESGRGKCPFEPAQRSAAVMAGGVLYAATV 192
Query: 186 YEFRSI-PDIRRS--RHPHSLRTEETPMHWLNDAEFVFSVLVRESKASAVGDDDKVYYFF 242
+ P I R+ R +RT+ P WLN FV +V + ++ DD++Y+FF
Sbjct: 193 KNYLGTEPIITRAVGRAEDWIRTDTLPS-WLNAPAFVAAVALSPAEWGDEDGDDEIYFFF 251
Query: 243 TERATEEGSGSFTQSRSSHRVARVARVCKGDLGGKKILQKKWTSFLKARLICHIPLY--- 299
TE T S+ + + V RVARVC GDLGG+K LQ++WT+FLKA L+C P +
Sbjct: 252 TE--TSRAFDSYERIK----VPRVARVCAGDLGGRKTLQQRWTTFLKADLLCPGPEHGRA 305
Query: 300 -ETLRGVCSLDAETSSRTH-FYAAFTLSTQWKTLEASAICRYDLAEIQAVFAGPYMEYQ- 356
L+ V L E + T FY F S+QW+ SA+C + +I+ V GP+ E +
Sbjct: 306 SSVLQDVAVLRPELGAGTPIFYGIF--SSQWEGATISAVCAFRPQDIRTVLNGPFRELKH 363
Query: 357 DGSRRWGRYEGGVPEPRPGSCITDSLRSQGYNSSQDLPSLVLDFVKLHPLMARPVVPTRG 416
D +R + VP+PRPG CIT++++ + + SS LP VL F++ HPLM RPV P G
Sbjct: 364 DCNRGLPVVDNDVPQPRPGECITNNMKLRHFGSSLSLPDRVLTFIRDHPLMDRPVFPADG 423
Query: 417 RPLLLKRNIRYTHLTGTPVTTPAGPTYDLLFLGTADGWIHKAVVLGSGMHIIEETQVFRE 476
PLL+ + Y + VT+ +G YD+L+LGT DG +H+AV +G+ + ++E+ +F E
Sbjct: 424 HPLLVTTDTAYLRVVAHRVTSLSGKEYDVLYLGTEDGHLHRAVRIGAQLSVLEDLALFPE 483
Query: 477 SQSVENLVISLLQHS-LYVGAPSGVIQLPLSSCSRYRSCYDCILARDPYCGWDPGTHACA 535
Q VEN+ L HS L VG+ + V Q+ ++C R +SC +CILA+DP C W C
Sbjct: 484 PQPVENM---KLYHSWLLVGSRTEVTQVNTTNCGRLQSCSECILAQDPVCAWSFRLDECV 540
Query: 536 AATTIANRSQGSRTALIQDIERGNRGCESSRDTGPPPPLKTRSVLRGDDVLLPCDQPSNL 595
A G L+QDIE + ++ G P + V V+LPC S
Sbjct: 541 A-------HAGEHRGLVQDIESADVSSLCPKEPGERPVVFEVPVATAAHVVLPCSPSSAW 593
Query: 596 ARALW-LLNGSMGLSDGQGGYRVGVDGLLVTDAQPEHSGNYGCYAEENGLRTLLASYSLT 654
A +W +G L+ + G V V P G Y C +E G ++A+YSL
Sbjct: 594 ASCVWHQPSGVTALTPRRDGLEVVV--------TPGAMGAYACECQEGGAAHVVAAYSLV 645
Query: 655 VRPATPAPAPKAPATPGAQLAPDVRLLYVLAIAALGGLCLILASSLLYVACLREGRRGRR 714
+ AP T GA LA G ILA+SL + R +R R+
Sbjct: 646 W--GSQRDAPSRAHTVGAGLA--------------GFFLGILAASLTLILIGRRQQRRRQ 689
Query: 715 RK 716
R+
Sbjct: 690 RE 691
>gi|21361914 semaphorin B [Homo sapiens]
Length = 761
Score = 341 bits (874), Expect = 2e-93
Identities = 247/692 (35%), Positives = 344/692 (49%), Gaps = 80/692 (11%)
Query: 48 HFKGQAQNYSTLLLEEASARLLVGARGALFSLSANDIGDGAHKE-IHWEASPEMQSKCHQ 106
H KG Q++ TLLL L VGAR A+ +L D G K I W AS +S+C
Sbjct: 57 HQKG-LQDFDTLLLSGDGNTLYVGAREAILALDIQDPGVPRLKNMIPWPASDRKKSECAF 115
Query: 107 KGKNNQTECFNHVRFLQRLNSTHLYACGTHAFQPLCAAIDAE-AFTLPTSFE---EGKEK 162
K K+N+T+CFN +R L N THLY CGT AF P C I+ + ++ LP S + EGK +
Sbjct: 116 KKKSNETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQ 175
Query: 163 CPYDPARGFTGLIIDGGLYTATRYEFR-SIPDIRRSRHPHSLRTEETPMHWLN-DAEFVF 220
P+DPA T +++DG LY+ T F S P + R+ + + + WL+ DA FV
Sbjct: 176 SPFDPAHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNFLRWLHHDASFV- 234
Query: 221 SVLVRESKASAVGDDDKVYYFFTERATEEGSGSFTQSRSSHRVARVARVCKGDLGGKKIL 280
+A+ VY+FF E A+E F H +RVARVCK D+GG+K+L
Sbjct: 235 ---------AAIPSTQVVYFFFEETASE-----FDFFERLH-TSRVARVCKNDVGGEKLL 279
Query: 281 QKKWTSFLKARLICHIP---LYETLRGVCSLDAETSSRTHFYAAFTLSTQWKTLEASAIC 337
QKKWT+FLKA+L+C P + +R L A++ + H YA FT Q +SA+C
Sbjct: 280 QKKWTTFLKAQLLCTQPGQLPFNVIRHAVLLPADSPTAPHIYAVFTSQWQVGGTRSSAVC 339
Query: 338 RYDLAEIQAVFAGPYMEYQDGSRRWGRYEGGVPEPRPGSCITDSLRSQGYNSSQDLPSLV 397
+ L +I+ VF G Y E + RW Y G PRPGSC S G +S +
Sbjct: 340 AFSLLDIERVFKGKYKELNKETSRWTTYRGPETNPRPGSC------SVGPSSDK-----A 388
Query: 398 LDFVKLHPLMARPVVPTRGRPLLLKRNIRYTHLTGTPVTTPAGPTYDLLFLGTADGWIHK 457
L F+K H LM VV G PLL+K + YT L G ++ +++LGT G +HK
Sbjct: 389 LTFMKDHFLMDEQVV---GTPLLVKSGVEYTRLAVETAQGLDGHSHLVMYLGTTTGSLHK 445
Query: 458 AVVLG-SGMHIIEETQVFRESQSVENLVISLLQHSLYVGAPSGVIQLPLSSCSRYRSCYD 516
AVV G S H++EE Q+F + + V NL ++ Q +++VG GV ++P ++CS Y SC D
Sbjct: 446 AVVSGDSSAHLVEEIQLFPDPEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVYESCVD 505
Query: 517 CILARDPYCGWDPGTHACAAATTIANRSQGSRTALIQDIERGNR--GCES---SRDTGP- 570
C+LARDP+C WDP + C S + + QD+ERGN C S SR P
Sbjct: 506 CVLARDPHCAWDPESRTCCLL------SAPNLNSWKQDMERGNPEWACASGPMSRSLRPQ 559
Query: 571 --PPPLKTRSVLRGDDVLLPCDQPSNLARALWLLNGSMGLSDGQGGYRVGVDGLLVTDAQ 628
P +K + + LPC S LA W S G + +G L+ Q
Sbjct: 560 SRPQIIKEVLAVPNSILELPCPHLSALASYYW----SHGPAAVPEASSTVYNGSLLLIVQ 615
Query: 629 PEHSGNYGCYAEENGLRTLLASYSLTVRPATPAPAPKAPATP-------------GAQLA 675
G Y C+A ENG + SY + + T A P+ P GA LA
Sbjct: 616 DGVGGLYQCWATENGFSYPVISYWVDSQDQTLALDPELAGIPREHVKVPLTRVSGGAALA 675
Query: 676 PD-------VRLLYVLAIAALGGLCLILASSL 700
V + + A+ G L +++AS L
Sbjct: 676 AQQSYWPHFVTVTVLFALVLSGALIILVASPL 707
>gi|5174673 semaphorin 3A precursor [Homo sapiens]
Length = 771
Score = 339 bits (869), Expect = 7e-93
Identities = 230/666 (34%), Positives = 330/666 (49%), Gaps = 72/666 (10%)
Query: 34 PRMTIPYEELSGTRH---FKGQAQN--YSTLLLEEASARLLVGARGALFSLSANDIGDGA 88
PR+ + Y+E+ + + F G A + Y T LL+E +RL VGA+ +FS +I D
Sbjct: 30 PRLKLSYKEMLESNNVITFNGLANSSSYHTFLLDEERSRLYVGAKDHIFSFDLVNIKD-- 87
Query: 89 HKEIHWEASPEMQSKCHQKGKNNQTECFNHVRFLQRLNSTHLYACGTHAFQPLCAAIDA- 147
++I W S + +C GK+ EC N ++ L+ N THLYACGT AF P+C I+
Sbjct: 88 FQKIVWPVSYTRRDECKWAGKDILKECANFIKVLKAYNQTHLYACGTGAFHPICTYIEIG 147
Query: 148 -----EAFTLPTS-FEEGKEKCPYDPARGFTGLIIDGGLYTATRYEF--RSIPDIRRSRH 199
F L S FE G+ K PYDP L+IDG LY+ T +F R R H
Sbjct: 148 HHPEDNIFKLENSHFENGRGKSPYDPKLLTASLLIDGELYSGTAADFMGRDFAIFRTLGH 207
Query: 200 PHSLRTEETPMHWLNDAEFVFSVLVRESKASAVGDDDKVYYFFTERATE-EGSGSFTQSR 258
H +RTE+ WLND +F+ + L+ ES +DDKVY+FF E A + E SG T
Sbjct: 208 HHPIRTEQHDSRWLNDPKFISAHLISESDNP---EDDKVYFFFRENAIDGEHSGKATH-- 262
Query: 259 SSHRVARVARVCKGDLGGKKILQKKWTSFLKARLICHIP-------LYETLRGVCSLDAE 311
AR+ ++CK D GG + L KWT+FLKARLIC +P ++ L+ V ++ +
Sbjct: 263 -----ARIGQICKNDFGGHRSLVNKWTTFLKARLICSVPGPNGIDTHFDELQDVFLMNFK 317
Query: 312 TSSRTHFYAAFTLSTQWKTLEASAICRYDLAEIQAVFAGPYMEYQDGSRRWGRYEGGVPE 371
Y FT S+ + SA+C Y +++++ VF GPY + +W Y+G VP
Sbjct: 318 DPKNPVVYGVFTTSS--NIFKGSAVCMYSMSDVRRVFLGPYAHRDGPNYQWVPYQGRVPY 375
Query: 372 PRPGSCITDSLRSQGYNSSQDLPSLVLDFVKLHPLMARPVVPTRGRPLLLKRNIRY--TH 429
PRPG+C S G++S++DLP V+ F + HP M PV P RP+++K ++ Y T
Sbjct: 376 PRPGTC--PSKTFGGFDSTKDLPDDVITFARSHPAMYNPVFPMNNRPIVIKTDVNYQFTQ 433
Query: 430 LTGTPVTTPAGPTYDLLFLGTADGWIHKAVVLGSGMH------IIEETQVFRESQSVENL 483
+ V G YD++F+GT G + K V + ++EE VFRE ++ +
Sbjct: 434 IVVDRVDAEDG-QYDVMFIGTDVGTVLKVVSIPKETWYDLEEVLLEEMTVFREPTAISAM 492
Query: 484 VISLLQHSLYVGAPSGVIQLPLSSCSRY-RSCYDCILARDPYCGWDPGTHACAAATTIAN 542
+S Q LY+G+ +GV QLPL C Y ++C +C LARDPYC WD AC+ A
Sbjct: 493 ELSTKQQQLYIGSTAGVAQLPLHRCDIYGKACAECCLARDPYCAWDGS--ACSRYFPTAK 550
Query: 543 RSQGSRTALIQDIERGN-----RGCESSRDTGPPPPLKTRSVLRGDDVLLPCDQPSNLAR 597
R RT QDI G+ G P + + L C S A
Sbjct: 551 R----RTRR-QDIRNGDPLTHCSDLHHDNHHGHSPEERIIYGVENSSTFLECSPKSQRAL 605
Query: 598 ALWLLNGSMGLSDGQGGYRVGVD--------GLLVTDAQPEHSGNYGCYAEENGLRTLLA 649
W + + + VD GLL+ Q + SGNY C+A E+G L
Sbjct: 606 VYW----QFQRRNEERKEEIRVDDHIIRTDQGLLLRSLQQKDSGNYLCHAVEHGFIQTLL 661
Query: 650 SYSLTV 655
+L V
Sbjct: 662 KVTLEV 667
>gi|41406086 semaphorin 3D [Homo sapiens]
Length = 777
Score = 327 bits (839), Expect = 2e-89
Identities = 222/662 (33%), Positives = 335/662 (50%), Gaps = 61/662 (9%)
Query: 34 PRMTIPYEEL---SGTRHFKGQAQ--NYSTLLLEEASARLLVGARGALFSLSANDIGDGA 88
PR+ + Y++L + F G ++ ++ TLLL+E RLL+GA+ +F LS D+
Sbjct: 43 PRLKLTYKDLLLSNSCIPFLGSSEGLDFQTLLLDEERGRLLLGAKDHIFLLSLVDLNKN- 101
Query: 89 HKEIHWEASPEMQSKCHQKGKNNQTECFNHVRFLQRLNSTHLYACGTHAFQPLCAAIDAE 148
K+I+W A+ E C GK+ TEC N +R LQ N TH+Y CGT AF P+C ID
Sbjct: 102 FKKIYWPAAKERVELCKLAGKDANTECANFIRVLQPYNKTHIYVCGTGAFHPICGYIDLG 161
Query: 149 A------FTLPT-SFEEGKEKCPYDPARGFTGLIIDGGLYTATRYEFRSIPD-IRRSRHP 200
F L T + E G+ KCP+DP + F ++ D LY+ T +F RS P
Sbjct: 162 VYKEDIIFKLDTHNLESGRLKCPFDPQQPFASVMTDEYLYSGTASDFLGKDTAFTRSLGP 221
Query: 201 ----HSLRTEETPMHWLNDAEFVFSVLVRESKASAVGDDDKVYYFFTERATEEGSGSFTQ 256
H +RT+ + +WLN A+F+ + + ++ DDDK+Y+FF E +++EGS S
Sbjct: 222 THDHHYIRTDISEHYWLNGAKFIGTFFIPDTYNP---DDDKIYFFFRE-SSQEGSTS--- 274
Query: 257 SRSSHRVARVARVCKGDLGGKKILQKKWTSFLKARLICHIP-------LYETLRGVCSLD 309
++RV RVCK D+GG++ L KWT+FLKARLIC IP ++ L+ + L
Sbjct: 275 --DKTILSRVGRVCKNDVGGQRSLINKWTTFLKARLICSIPGSDGADTYFDELQDIYLLP 332
Query: 310 AETSSRTHFYAAFTLSTQWKTLEASAICRYDLAEIQAVFAGPYMEYQDGSRRWGRYEGGV 369
Y FT T + SA+C Y +A+I+AVF GPY + RW +Y+G +
Sbjct: 333 TRDERNPVVYGVFT--TTSSIFKGSAVCVYSMADIRAVFNGPYAHKESADHRWVQYDGRI 390
Query: 370 PEPRPGSCITDSLRSQGYNSSQDLPSLVLDFVKLHPLMARPVVPTRGRPLLLKRNIRY-- 427
P PRPG+C + + S++D P V+ F+K H +M + V P G P + N+ Y
Sbjct: 391 PYPRPGTCPSKTY-DPLIKSTRDFPDDVISFIKRHSVMYKSVYPVAGGPTFKRINVDYRL 449
Query: 428 THLTGTPVTTPAGPTYDLLFLGTADGWIHKAVVLGSGMH-----IIEETQVFRESQSVEN 482
T + V G YD++FLGT G + K V + ++EE Q+F+ S + N
Sbjct: 450 TQIVVDHVIAEDG-QYDVMFLGTDIGTVLKVVSISKEKWNMEEVVLEELQIFKHSSIILN 508
Query: 483 LVISLLQHSLYVGAPSGVIQLPLSSCSRY-RSCYDCILARDPYCGWDPGTHACAAATTIA 541
+ +SL Q LY+G+ G++QL L C Y ++C DC LARDPYC WD + A T+
Sbjct: 509 MELSLKQQQLYIGSRDGLVQLSLHRCDTYGKACADCCLARDPYCAWDGNACSRYAPTS-- 566
Query: 542 NRSQGSRTALIQDIERGN--RGCESSRDTGPPPPLKTRSV--LRGDDVLLPCDQPSNLAR 597
R A QD++ G+ C D+ + + + + L C S A
Sbjct: 567 -----KRRARRQDVKYGDPITQCWDIEDSISHETADEKVIFGIEFNSTFLECIPKSQQAT 621
Query: 598 ALWLL--NGSMGLSDGQGGYRV--GVDGLLVTDAQPEHSGNYGCYAEENGLRTLLASYSL 653
W + +G + + R+ GLL+ Q + SG Y C A+E+ + +L
Sbjct: 622 IKWYIQRSGDEHREELKPDERIIKTEYGLLIRSLQKKDSGMYYCKAQEHTFIHTIVKLTL 681
Query: 654 TV 655
V
Sbjct: 682 NV 683
>gi|4759092 semaphorin 3B isoform 1 precursor [Homo sapiens]
Length = 749
Score = 320 bits (819), Expect = 5e-87
Identities = 240/750 (32%), Positives = 350/750 (46%), Gaps = 74/750 (9%)
Query: 8 LLLSILTATAVPGPSLRRPSRELDATPRMTIPYEELS---GTRHFKGQAQN-YSTLLLEE 63
LL ++ +A P P PR+ + ++EL G + F + Y LL++E
Sbjct: 15 LLWAVGLGSAAPSP------------PRLRLSFQELQAWHGLQTFSLERTCCYQALLVDE 62
Query: 64 ASARLLVGARGALFSLSANDIGDGAHKEIHWEASPEMQSKCHQKGKNNQTECFNHVRFLQ 123
RL VGA + SL+ ++I A K++ W A E + +C+ GK+ TEC N V+ L
Sbjct: 63 ERGRLFVGAENHVASLNLDNISKRA-KKLAWPAPVEWREECNWAGKDIGTECMNFVKLLH 121
Query: 124 RLNSTHLYACGTHAFQPLCAAID----AEAFTL---PTSFEEGKEKCPYDPARGFTGLII 176
N THL ACGT AF P CA ++ AE L P E+GK K PYDP +++
Sbjct: 122 AYNRTHLLACGTGAFHPTCAFVEVGHRAEEPVLRLDPGRIEDGKGKSPYDPRHRAASVLV 181
Query: 177 DGGLYTATRYEF--RSIPDIRRSRHPHSLRTEETPMHWLNDAEFVFSVLVRESKASAVGD 234
LY+ + R R SLRTE WLN+ +FV + ES+ D
Sbjct: 182 GEELYSGVAADLMGRDFTIFRSLGQRPSLRTEPHDSRWLNEPKFVKVFWIPESENP---D 238
Query: 235 DDKVYYFFTERATEEGSGSFTQSRSSHRVARVARVCKGDLGGKKILQKKWTSFLKARLIC 294
DDK+Y+FF E A E S V+RV ++C+ D+GG++ L KWT+FLKARL+C
Sbjct: 239 DDKIYFFFRETAVEAAPALGRLS-----VSRVGQICRNDVGGQRSLVNKWTTFLKARLVC 293
Query: 295 HIP------LYETLRGVCSLDAETSSRTHFYAAFTLSTQWKTLEASAICRYDLAEIQAVF 348
+P ++ L+ V L + YA F ST + SA+C Y + +++ F
Sbjct: 294 SVPGVEGDTHFDQLQDVFLLSSRDHRTPLLYAVF--STSSSIFQGSAVCVYSMNDVRRAF 351
Query: 349 AGPYMEYQDGSRRWGRYEGGVPEPRPGSCITDSLRSQGYNSSQDLPSLVLDFVKLHPLMA 408
GP+ + +W Y+G VP PRPG C + + + ++S++D P V+ F + HPLM
Sbjct: 352 LGPFAHKEGPMHQWVSYQGRVPYPRPGMCPSKTFGT--FSSTKDFPDDVIQFARNHPLMY 409
Query: 409 RPVVPTRGRPLLLK--RNIRYTHLTGTPVTTPAGPTYDLLFLGTADGWIHKAVVLGSGMH 466
V+PT GRPL L+ N +T + V G YD+LF+GT G + K + + G
Sbjct: 410 NSVLPTGGRPLFLQVGANYTFTQIAADRVAAADG-HYDVLFIGTDVGTVLKVISVPKGSR 468
Query: 467 ------IIEETQVFRESQSVENLVISLLQHSLYVGAPSGVIQLPLSSCSRY-RSCYDCIL 519
++EE VF +S +V ++ IS +H LYV + S V Q+ L C+ + R C +C L
Sbjct: 469 PSAEGLLLEELHVFEDSAAVTSMQISSKRHQLYVASRSAVAQIALHRCAAHGRVCTECCL 528
Query: 520 ARDPYCGWDPGTHACAAATTIANRSQGSRTALIQDIERGNRGCESSRDTGPPPPLKTRSV 579
ARDPYC WD A T + R QD+ G+ S D+ P L+ +
Sbjct: 529 ARDPYCAWDG-----VACTRF--QPSAKRRFRRQDVRNGDPSTLCSGDSSRPALLEHKVF 581
Query: 580 -LRGDDVLLPCDQPSNLARALWLLNGSMGLSDGQGGYRVGVD----GLLVTDAQPEHSGN 634
+ G L C+ S AR W + + Q + GLL+ + SG
Sbjct: 582 GVEGSSAFLECEPRSLQARVEWTFQRAGVTAHTQVLAEERTERTARGLLLRRLRRRDSGV 641
Query: 635 YGCYAEENGLRTLLASYSLTVRPATPA--------PAPKAPATPGAQLAPDVRLLYVLAI 686
Y C A E G L SL V AT A AP AP P ++L+
Sbjct: 642 YLCAAVEQGFTQPLRRLSLHVLSATQAERLARAEEAAPAAPPGPKLWYRDFLQLVEPGGG 701
Query: 687 AALGGLCLILASSLLYVACLREGRRGRRRK 716
+ L + L L R+GR R+
Sbjct: 702 GSANSLRMCRPQPALQSLPLESRRKGRNRR 731
>gi|54607089 semaphorin 3B isoform 2 precursor [Homo sapiens]
Length = 748
Score = 319 bits (817), Expect = 8e-87
Identities = 239/750 (31%), Positives = 351/750 (46%), Gaps = 75/750 (10%)
Query: 8 LLLSILTATAVPGPSLRRPSRELDATPRMTIPYEELS---GTRHFKGQAQN-YSTLLLEE 63
LL ++ +A P P PR+ + ++EL G + F + Y LL++E
Sbjct: 15 LLWAVGLGSAAPSP------------PRLRLSFQELQAWHGLQTFSLERTCCYQALLVDE 62
Query: 64 ASARLLVGARGALFSLSANDIGDGAHKEIHWEASPEMQSKCHQKGKNNQTECFNHVRFLQ 123
RL VGA + SL+ ++I A K++ W A E + +C+ GK+ TEC N V+ L
Sbjct: 63 ERGRLFVGAENHVASLNLDNISKRA-KKLAWPAPVEWREECNWAGKDIGTECMNFVKLLH 121
Query: 124 RLNSTHLYACGTHAFQPLCAAID----AEAFTL---PTSFEEGKEKCPYDPARGFTGLII 176
N THL ACGT AF P CA ++ AE L P E+GK K PYDP +++
Sbjct: 122 AYNRTHLLACGTGAFHPTCAFVEVGHRAEEPVLRLDPGRIEDGKGKSPYDPRHRAASVLV 181
Query: 177 DGGLYTATRYEF--RSIPDIRRSRHPHSLRTEETPMHWLNDAEFVFSVLVRESKASAVGD 234
LY+ + R R SLRTE WLN+ +FV + ES+ D
Sbjct: 182 GEELYSGVAADLMGRDFTIFRSLGQRPSLRTEPHDSRWLNEPKFVKVFWIPESENP---D 238
Query: 235 DDKVYYFFTERATEEGSGSFTQSRSSHRVARVARVCKGDLGGKKILQKKWTSFLKARLIC 294
DDK+Y+FF E A E S V+RV ++C+ D+GG++ L KWT+FLKARL+C
Sbjct: 239 DDKIYFFFRETAVEAAPALGRLS-----VSRVGQICRNDVGGQRSLVNKWTTFLKARLVC 293
Query: 295 HIP------LYETLRGVCSLDAETSSRTHFYAAFTLSTQWKTLEASAICRYDLAEIQAVF 348
+P ++ L+ V L + YA F+ S+ + SA+C Y + +++ F
Sbjct: 294 SVPGVEGDTHFDQLQDVFLLSSRDHRTPLLYAVFSTSS---IFQGSAVCVYSMNDVRRAF 350
Query: 349 AGPYMEYQDGSRRWGRYEGGVPEPRPGSCITDSLRSQGYNSSQDLPSLVLDFVKLHPLMA 408
GP+ + +W Y+G VP PRPG C + + + ++S++D P V+ F + HPLM
Sbjct: 351 LGPFAHKEGPMHQWVSYQGRVPYPRPGMCPSKTFGT--FSSTKDFPDDVIQFARNHPLMY 408
Query: 409 RPVVPTRGRPLLLK--RNIRYTHLTGTPVTTPAGPTYDLLFLGTADGWIHKAVVLGSGMH 466
V+PT GRPL L+ N +T + V G YD+LF+GT G + K + + G
Sbjct: 409 NSVLPTGGRPLFLQVGANYTFTQIAADRVAAADG-HYDVLFIGTDVGTVLKVISVPKGSR 467
Query: 467 ------IIEETQVFRESQSVENLVISLLQHSLYVGAPSGVIQLPLSSCSRY-RSCYDCIL 519
++EE VF +S +V ++ IS +H LYV + S V Q+ L C+ + R C +C L
Sbjct: 468 PSAEGLLLEELHVFEDSAAVTSMQISSKRHQLYVASRSAVAQIALHRCAAHGRVCTECCL 527
Query: 520 ARDPYCGWDPGTHACAAATTIANRSQGSRTALIQDIERGNRGCESSRDTGPPPPLKTRSV 579
ARDPYC WD A T + R QD+ G+ S D+ P L+ +
Sbjct: 528 ARDPYCAWDG-----VACTRF--QPSAKRRFRRQDVRNGDPSTLCSGDSSRPALLEHKVF 580
Query: 580 -LRGDDVLLPCDQPSNLARALWLLNGSMGLSDGQGGYRVGVD----GLLVTDAQPEHSGN 634
+ G L C+ S AR W + + Q + GLL+ + SG
Sbjct: 581 GVEGSSAFLECEPRSLQARVEWTFQRAGVTAHTQVLAEERTERTARGLLLRRLRRRDSGV 640
Query: 635 YGCYAEENGLRTLLASYSLTVRPATPA--------PAPKAPATPGAQLAPDVRLLYVLAI 686
Y C A E G L SL V AT A AP AP P ++L+
Sbjct: 641 YLCAAVEQGFTQPLRRLSLHVLSATQAERLARAEEAAPAAPPGPKLWYRDFLQLVEPGGG 700
Query: 687 AALGGLCLILASSLLYVACLREGRRGRRRK 716
+ L + L L R+GR R+
Sbjct: 701 GSANSLRMCRPQPALQSLPLESRRKGRNRR 730
>gi|9910362 semaphorin sem2 [Homo sapiens]
Length = 782
Score = 315 bits (808), Expect = 9e-86
Identities = 239/737 (32%), Positives = 333/737 (45%), Gaps = 75/737 (10%)
Query: 2 WGRLW---PLLLSILTATAVPGPSLRRPSRELDATPRMTIPYEELSGTRH---FKGQ--A 53
W W LLL ++ PGPS+ PR+ + Y +L F G +
Sbjct: 6 WAICWLLGGLLLHGGSSGPSPGPSV----------PRLRLSYRDLLSANRSAIFLGPQGS 55
Query: 54 QNYSTLLLEEASARLLVGARGALFSLSANDIGDGAHKEIHWEASPEMQSKCHQKGKNNQT 113
N + L+E RL +G AL+SL + +E+ W P + +C +KG++ T
Sbjct: 56 LNLQAMYLDEYRDRLFLGGLDALYSLRLDQAWPDP-REVLWPPQPGQREECVRKGRDPLT 114
Query: 114 ECFNHVRFLQRLNSTHLYACGTHAFQPLCAAI------DAEAFTLPTSFEEGKEKCPYDP 167
EC N VR LQ N THL ACGT AFQP CA I + P S E G+ +CP++P
Sbjct: 115 ECANFVRVLQPHNRTHLLACGTGAFQPTCALITVGHRGEHVLHLEPGSVESGRGRCPHEP 174
Query: 168 ARGFTGLIIDGGLYTATRYEFRSIPD-IRRSRHPHSLRTEETPMHWLNDAEFVFSVLVRE 226
+R F IDG LYT +F I RS P ++ L+D FV + + E
Sbjct: 175 SRPFASTFIDGELYTGLTADFLGREAMIFRSGGPRPALRSDSDQSLLHDPRFVMAARIPE 234
Query: 227 SKASAVGDDDKVYYFFTERATEEGSGSFTQSRSSHRVARVARVCKGDLGGKKILQKKWTS 286
+ D+DKVY+FF+E GS + V+RV RVC D GG+++L KW++
Sbjct: 235 NSDQ---DNDKVYFFFSETVPSPDGGS-----NHVTVSRVGRVCVNDAGGQRVLVNKWST 286
Query: 287 FLKARLICHIP-------LYETLRGVCSLDAETSSRTHFYAAFTLSTQWKTLEASAICRY 339
FLKARL+C +P ++ L V L + YA F ST + A+C Y
Sbjct: 287 FLKARLVCSVPGPGGAETHFDQLEDVFLLWPKAGKSLEVYALF--STVSAVFQGFAVCVY 344
Query: 340 DLAEIQAVFAGPYMEYQDGSRRWGRYEGGVPEPRPGSCITDSLRSQG--YNSSQDLPSLV 397
+A+I VF GP+ +WG Y G VP PRPG C + G + S++D P V
Sbjct: 345 HMADIWEVFNGPFAHRDGPQHQWGPYGGKVPFPRPGVCPSKMTAQPGRPFGSTKDYPDEV 404
Query: 398 LDFVKLHPLMARPVVPTRGRPLLLKRNI-RYTHLTGTPVTTPAGPTYDLLFLGTADGWIH 456
L F + HPLM PV P GRP+L+K ++ + H TYD++FLGT G +
Sbjct: 405 LQFARAHPLMFWPVRPRHGRPVLVKTHLAQQLHQIVVDRVEAEDGTYDVIFLGTDSGSVL 464
Query: 457 KAVVLGSGMH------IIEETQVFRESQSVENLVISLLQHSLYVGAPSGVIQLPLSSCSR 510
K + L +G ++EE QVF+ + + IS+ + LYVG+ GV QL L C
Sbjct: 465 KVIALQAGGSAEPEEVVLEELQVFKVPTPITEMEISVKRQMLYVGSRLGVAQLRLHQCET 524
Query: 511 Y-RSCYDCILARDPYCGWDPGTHACAAATTIANRSQGSRTALIQDIERGNRG--CESSRD 567
Y +C +C LARDPYC WD A+ T S G R QDI GN C
Sbjct: 525 YGTACAECCLARDPYCAWD------GASCTHYRPSLGKRRFRRQDIRHGNPALQCLGQSQ 578
Query: 568 TGPPPPLKTRSVLRG---DDVLLPCDQPSNLARALWLLN--GSMGLSDGQGGYRV--GVD 620
L +++ G + L C S A WLL G G + RV
Sbjct: 579 EEEAVGLVAATMVYGTEHNSTFLECLPKSPQAAVRWLLQRPGDEGPDQVKTDERVLHTER 638
Query: 621 GLLVTDAQPEHSGNYGCYAEENGLRTLLASYSLTVRPAT-------PAPAPKAPATPGAQ 673
GLL +G Y C E+G + +L V A+ P P P+ P G
Sbjct: 639 GLLFRRLSRFDAGTYTCTTLEHGFSQTVVRLALVVIVASQLDNLFPPEPKPEEPPARGGL 698
Query: 674 LAPDVRLLYVLAIAALG 690
+ + Y + +G
Sbjct: 699 ASTPPKAWYKDILQLIG 715
>gi|188497703 semaphorin 3F [Homo sapiens]
Length = 785
Score = 299 bits (765), Expect = 8e-81
Identities = 228/738 (30%), Positives = 335/738 (45%), Gaps = 101/738 (13%)
Query: 12 ILTATAVPGPSLRRPSRE-LDATPRMTIPYEEL--SGTRHFKGQAQN---YSTLLLEEAS 65
+L A+ + G P+++ L ATPR+ + ++EL +GT HF N Y LL +E
Sbjct: 7 LLWASLLTGAWPSFPTQDHLPATPRVRLSFKELKATGTAHFFNFLLNTTDYRILLKDEDH 66
Query: 66 ARLLVGARGALFSLSANDIGDGAHKE---IHWEASPEMQSKCHQKGKNNQTECFNHVRFL 122
R+ VG++ + SL +DI ++E IHW ASP+ +C GK+ EC N VR +
Sbjct: 67 DRMYVGSKDYVLSLDLHDI----NREPLIIHWAASPQRIEECVLSGKDVNGECGNFVRLI 122
Query: 123 QRLNSTHLYACGTHAFQPLCA-------------------------AIDAEAFTLPTS-- 155
Q N THLY CGT A+ P+C A D +PT+
Sbjct: 123 QPWNRTHLYVCGTGAYNPMCTYVNRGRRAQATPWTQTQAVRGRGSRATDGALRPMPTAPR 182
Query: 156 -----------FEEGKEKCPYDPARGFTGLIIDGGLYTATRYEFRSIPD--IRRSRHPHS 202
E GK KCPYDP +I+ LY +F R +
Sbjct: 183 QDYIFYLEPERLESGKGKCPYDPKLDTASALINEELYAGVYIDFMGTDAAIFRTLGKQTA 242
Query: 203 LRTEETPMHWLNDAEFVFSVLVRESKASAVGDDDKVYYFFTERATEEGSGSFTQSRSSHR 262
+RT++ WLND F+ + L+ +S A +DDK+Y+FF ER+ E +S
Sbjct: 243 MRTDQYNSRWLNDPSFIHAELIPDS---AERNDDKLYFFFRERSAEA-------PQSPAV 292
Query: 263 VARVARVCKGDLGGKKILQKKWTSFLKARLICHIP-------LYETLRGVCSLDAETSSR 315
AR+ R+C D GG L KW++FLKARL+C +P ++ L+ V +
Sbjct: 293 YARIGRICLNDDGGHCCLVNKWSTFLKARLVCSVPGEDGIETHFDELQDVFVQQTQDVRN 352
Query: 316 THFYAAFTLSTQWKTLEASAICRYDLAEIQAVFAGPYMEYQDGSRRWGRYEGGVPEPRPG 375
YA FT S SA+C Y +A+I+ VF GP+ + + +W + G +P PRPG
Sbjct: 353 PVIYAVFTSSGS--VFRGSAVCVYSMADIRMVFNGPFAHKEGPNYQWMPFSGKMPYPRPG 410
Query: 376 SCITDSLRSQGYNSSQDLPSLVLDFVKLHPLMARPVVPTRGRPLLLKRNIRYTHLT-GTP 434
+C + + S++D P V++F++ HPLM + V P + RPL+++ Y T
Sbjct: 411 TCPGGTF-TPSMKSTKDYPDEVINFMRSHPLMYQAVYPLQRRPLVVRTGAPYRLTTIAVD 469
Query: 435 VTTPAGPTYDLLFLGTADGWIHKAVVLGSGMH-----IIEETQVFRESQSVENLVISLLQ 489
A Y++LFLGT G + K +VL ++EE +VF++ V+ + IS +
Sbjct: 470 QVDAADGRYEVLFLGTDRGTVQKVIVLPKDDQELEELMLEEVEVFKDPAPVKTMTISSKR 529
Query: 490 HSLYVGAPSGVIQLPLSSCSRY-RSCYDCILARDPYCGWDPGTHACAAATTIANRSQGSR 548
LYV + GV L L C Y +C DC LARDPYC WD AC+ T + R
Sbjct: 530 QQLYVASAVGVTHLSLHRCQAYGAACADCCLARDPYCAWD--GQACSRYT-----ASSKR 582
Query: 549 TALIQDIERGN--RGCESSRDTGPPPPLKT-RSVLRGDDVLLPCDQPSNLARALWLLNGS 605
+ QD+ GN R C +++ + + G L C S A WL
Sbjct: 583 RSRRQDVRHGNPIRQCRGFNSNANKNAVESVQYGVAGSAAFLECQPRSPQATVKWLFQRD 642
Query: 606 MG----LSDGQGGYRVGVDGLLVTDAQPEHSGNYGCYAEENGLRTLLASYSLTV--RPAT 659
G + + GLL+ Q G Y C A EN + ++ L V R A
Sbjct: 643 PGDRRREIRAEDRFLRTEQGLLLRALQLSDRGLYSCTATENNFKHVVTRVQLHVLGRDAV 702
Query: 660 -----PAPAPKAPATPGA 672
P + AP PGA
Sbjct: 703 HAALFPPLSMSAPPPPGA 720
>gi|6912650 semaphorin 3E [Homo sapiens]
Length = 775
Score = 282 bits (721), Expect = 1e-75
Identities = 192/605 (31%), Positives = 289/605 (47%), Gaps = 56/605 (9%)
Query: 34 PRMTIPYEELSGTR-----HFKGQAQNYSTLLLEEASARLLVGARGALFSLSANDIGDGA 88
PR+ + ++EL H + T+LL+E RL VG R ++SLS I DG
Sbjct: 31 PRLRLSHKELLNLNRTSIFHSPFGFLDLHTMLLDEYQERLFVGGRDLVYSLSLERISDG- 89
Query: 89 HKEIHWEASPEMQSKCHQKGKNNQTECFNHVRFLQRLNSTHLYACGTHAFQPLCAAI--- 145
+KEIHW ++ +C KGK+ EC N+VR L N THL CGT AF P+CA I
Sbjct: 90 YKEIHWPSTALKMEECIMKGKD-AGECANYVRVLHHYNRTHLLTCGTGAFDPVCAFIRVG 148
Query: 146 ---DAEAFTLPTS-FEEGKEKCPYDPARGFTGLIIDGGLYTA--TRYEFRSIPDIRRSRH 199
+ F L + E G+ +CP+DP+ F +I L+ + Y R R
Sbjct: 149 YHLEDPLFHLESPRSERGRGRCPFDPSSSFISTLIGSELFAGLYSDYWSRDAAIFRSMGR 208
Query: 200 PHSLRTEETPMHWLNDAEFVFSVLVRESKASAVGDDDKVYYFFTERATEEGSGSFTQSRS 259
+RTE L + +FV S ++ +++ DD+KVY+FFTE+A E +
Sbjct: 209 LAHIRTEHDDERLLKEPKFVGSYMIPDNEDR---DDNKVYFFFTEKALEA-------ENN 258
Query: 260 SHRV-ARVARVCKGDLGGKKILQKKWTSFLKARLICHIP-------LYETLRGVCSLDAE 311
+H + RV R+C D+GG++IL KW++FLKARL+C +P ++ L V L
Sbjct: 259 AHAIYTRVGRLCVNDVGGQRILVNKWSTFLKARLVCSVPGMNGIDTYFDELEDVFLLPTR 318
Query: 312 TSSRTHFYAAFTLSTQWKTLEASAICRYDLAEIQAVFAGPYMEYQDGSRRWGRYEGGVPE 371
+ F +T AIC Y ++ I+A F GPY + W YEG VP
Sbjct: 319 DHKNPVIFGLF--NTTSNIFRGHAICVYHMSSIRAAFNGPYAHKEGPEYHWSVYEGKVPY 376
Query: 372 PRPGSCITDSLRSQGYNSSQDLPSLVLDFVKLHPLMARPVVPTRGRPLLLKRNIRYT--H 429
PRPGSC + Y +++D P + F + HPLM + + P +P+L+K + +Y
Sbjct: 377 PRPGSC-ASKVNGGRYGTTKDYPDDAIRFARSHPLMYQAIKPAHKKPILVKTDGKYNLKQ 435
Query: 430 LTGTPVTTPAGPTYDLLFLGTADGWIHKAVVL------GSGMHIIEETQVFRESQSVENL 483
+ V G YD+LF+GT +G + K + + I+EE Q+F++ + ++
Sbjct: 436 IAVDRVEAEDG-QYDVLFIGTDNGIVLKVITIYNQEMESMEEVILEELQIFKDPVPIISM 494
Query: 484 VISLLQHSLYVGAPSGVIQLPLSSCSRYRS-CYDCILARDPYCGWDPGTHACAAATTIAN 542
IS + LY+G+ S V Q+ C Y S C DC LARDPYC WD + +
Sbjct: 495 EISSKRQQLYIGSASAVAQVRFHHCDMYGSACADCCLARDPYCAWD----GISCSRYYPT 550
Query: 543 RSQGSRTALIQDIERGN--RGCESSRDTGPPPPLKTRSVLRG---DDVLLPCDQPSNLAR 597
+ R QD+ GN + C + G + G + LL C S A+
Sbjct: 551 GTHAKRRFRRQDVRHGNAAQQCFGQQFVGDALDKTEEHLAYGIENNSTLLECTPRSLQAK 610
Query: 598 ALWLL 602
+W +
Sbjct: 611 VIWFV 615
>gi|5454048 semaphorin 3C [Homo sapiens]
Length = 751
Score = 272 bits (695), Expect = 1e-72
Identities = 194/661 (29%), Positives = 313/661 (47%), Gaps = 67/661 (10%)
Query: 35 RMTIPYEELSGTR-----HFKGQAQNYSTLLLEEASARLLVGARGALFSLSANDIGDGAH 89
R+ + ++EL T+ +Y LL++E R+ VG++ + SL+ N+I A
Sbjct: 28 RVYLTFDELRETKTSEYFSLSHHPLDYRILLMDEDQDRIYVGSKDHILSLNINNISQEA- 86
Query: 90 KEIHWEASPEMQSKCHQKGKNNQTECFNHVRFLQRLNSTHLYACGTHAFQPLCAAI---- 145
+ W AS +C GK+ C N VR +Q N THLY CG+ AF P+C +
Sbjct: 87 LSVFWPASTIKVEECKMAGKDPTHGCGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGR 146
Query: 146 --DAEAFTLPTSFEEGKEKCPYDPARGFTGLIIDGGLYTATRYEFRSIPD--IRRSRHPH 201
+ + F + + E GK +C ++P ++I+ L++ +F R +
Sbjct: 147 RSEDQVFMIDSKCESGKGRCSFNPNVNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRN 206
Query: 202 SLRTEETPMHWLNDAEFVFSVLVRESKASAVGDDDKVYYFFTERATEEGSGSFTQSRSSH 261
++RT++ WL++ FV + ++ + +D KVY+FF E+ T+ +RS+
Sbjct: 207 AVRTDQHNSKWLSEPMFVDAHVIPDGTDP---NDAKVYFFFKEKLTD-------NNRSTK 256
Query: 262 RV-ARVARVCKGDLGGKKILQKKWTSFLKARLICHI-------PLYETLRGVCSLDAETS 313
++ + +AR+C D GG + L KWT+FLKARL+C + ++ L V L+ +
Sbjct: 257 QIHSMIARICPNDTGGLRSLVNKWTTFLKARLVCSVTDEDGPETHFDELEDVFLLETDNP 316
Query: 314 SRTHFYAAFTLSTQWKTLEASAICRYDLAEIQAVFAGPYMEYQDGSRRWGRYEGGVPEPR 373
T Y FT S+ + SA+C Y L++IQ VF GP+ + + + Y+G +P PR
Sbjct: 317 RTTLVYGIFTTSS--SVFKGSAVCVYHLSDIQTVFNGPFAHKEGPNHQLISYQGRIPYPR 374
Query: 374 PGSCITDSLRSQGYNSSQDLPSLVLDFVKLHPLMARPVVPTRGRPLLLK--RNIRYTHLT 431
PG+C + + ++++ P V+ F++ HPLM + P RPL+++ + +YT +
Sbjct: 375 PGTCPGGAF-TPNMRTTKEFPDDVVTFIRNHPLMYNSIYPIHKRPLIVRIGTDYKYTKIA 433
Query: 432 GTPVTTPAGPTYDLLFLGTADGWIHKAVVLG-----SGMHIIEETQVFRESQSVENLVIS 486
V G Y +LFLGT G + K VVL SG I+EE +VF+ + + IS
Sbjct: 434 VDRVNAADG-RYHVLFLGTDRGTVQKVVVLPTNNSVSGELILEELEVFKNHAPITTMKIS 492
Query: 487 LLQHSLYVGAPSGVIQLPLSSCSRY-RSCYDCILARDPYCGWDPGTHACAAATTIANRSQ 545
+ LYV + GV Q+ L C Y +C DC LARDPYC WD H+C+
Sbjct: 493 SKKQQLYVSSNEGVSQVSLHRCHIYGTACADCCLARDPYCAWD--GHSCSRF-----YPT 545
Query: 546 GSRTALIQDIERGN-----RGCESSRDTGPPPPLKTRSVLRGDDVLLPCDQPSNLARALW 600
G R + QD+ GN RG ++ ++ + L C S A W
Sbjct: 546 GKRRSRRQDVRHGNPLTQCRGFNLKAYRNAAEIVQYG--VKNNTTFLECAPKSPQASIKW 603
Query: 601 LLNGSMGLSDGQGGYRVG------VDGLLVTDAQPEHSGNYGCYAEENGLRTLLASYSLT 654
LL D + ++ GLL+ Q G Y C A EN + +A +
Sbjct: 604 LLQKD---KDRRKEVKLNERIIATSQGLLIRSVQGSDQGLYHCIATENSFKQTIAKINFK 660
Query: 655 V 655
V
Sbjct: 661 V 661
>gi|11991660 sema domain, transmembrane domain (TM), and cytoplasmic
domain, (semaphorin) 6A [Homo sapiens]
Length = 1030
Score = 228 bits (581), Expect = 2e-59
Identities = 166/497 (33%), Positives = 236/497 (47%), Gaps = 55/497 (11%)
Query: 90 KEIHWEASPEMQSKCHQKGKNNQTECFNHVRFLQRLNSTHLYACGTHAFQPLCAAIDAEA 149
K++ W++ C KGK+ EC N ++ L + N L+ CGT+AF P C +
Sbjct: 93 KKLTWKSRQADVDTCRMKGKHKD-ECHNFIKVLLKKNDDALFVCGTNAFNPSCRNYKMDT 151
Query: 150 FTLPTSFEEGKEKCPYDPARGFTGLIIDGGLYTATRYEFRSIPDI--RRSRHPHSLRTEE 207
G +CPYD L DG LY+AT +F +I + R +LRT +
Sbjct: 152 LEPFGDEFSGMARCPYDAKHANVALFADGKLYSATVTDFLAIDAVIYRSLGESPTLRTVK 211
Query: 208 TPMHWLNDAEFVFSVLVRESKASAVGDDDKVYYFFTERATEEGSGSFTQSRSSHRVARVA 267
WL + FV AV D +Y+FF E A E + RVA
Sbjct: 212 HDSKWLKEPYFV----------QAVDYGDYIYFFFREIAVEYNT------MGKVVFPRVA 255
Query: 268 RVCKGDLGG-KKILQKKWTSFLKARLICHIP-----LYETLRGVCSLDAETSSRTHFYAA 321
+VCK D+GG +++L+K+WTSFLKARL C +P + L+ V + + R A
Sbjct: 256 QVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNILQAVTDV-IRINGRDVVLAT 314
Query: 322 FTLSTQWKTLEASAICRYDLAEIQAVFAGPYMEYQDGSRRWGRY-EGGVPEPRPGSCITD 380
F ST + ++ SA+C YD+ +I +VF G + E + W + VP+PRPG C
Sbjct: 315 F--STPYNSIPGSAVCAYDMLDIASVFTGRFKEQKSPDSTWTPVPDERVPKPRPG-CCAG 371
Query: 381 SLRSQGYNSSQDLPSLVLDFVKLHPLMARPVVPTRGRPLLLKRNIRYTHLTGTPVTTPAG 440
S + Y +S + P L+F+K HPLM V RP L+ +RY LT V T AG
Sbjct: 372 SSSLERYATSNEFPDDTLNFIKTHPLMDEAVPSIFNRPWFLRTMVRY-RLTKIAVDTAAG 430
Query: 441 P--TYDLLFLGTADGWIHK--AVVLGSGM----HIIEETQVFR---------ESQSVENL 483
P + ++FLG+ G I K A + SG +EE V+ E + + +
Sbjct: 431 PYQNHTVVFLGSEKGIILKFLARIGNSGFLNDSLFLEEMSVYNSEKCSYDGVEDKRIMGM 490
Query: 484 VISLLQHSLYVGAPSGVIQLPLSSCSRYRSC-YDCILARDPYCGWDPGTHACAAATTIAN 542
+ SLYV + VI++PL C R+ C CI +RDPYCGW AC ++
Sbjct: 491 QLDRASSSLYVAFSTCVIKVPLGRCERHGKCKKTCIASRDPYCGWIKEGGAC------SH 544
Query: 543 RSQGSRTALIQDIERGN 559
S SR QDIERGN
Sbjct: 545 LSPNSRLTFEQDIERGN 561
>gi|24234729 semaphorin 6D isoform 1 precursor [Homo sapiens]
Length = 1011
Score = 221 bits (564), Expect = 2e-57
Identities = 164/541 (30%), Positives = 253/541 (46%), Gaps = 59/541 (10%)
Query: 23 LRRPSRELDATPRMTIPYEELSGTRHFKGQAQNYSTL------LLEEASARLLVGARGAL 76
LR S D P T+ Y F+G+ + L+ + L + R +
Sbjct: 18 LRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQLMLKIRDTLYIAGRDQV 77
Query: 77 FSLSANDIGDGA---HKEIHWEASPEMQSKCHQKGKNNQTECFNHVRFLQRLNSTHLYAC 133
++++ N++ +K++ W + + + C KGK+ EC N ++ N ++ C
Sbjct: 78 YTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKD-ECHNFIKVFVPRNDEMVFVC 136
Query: 134 GTHAFQPLCAAIDAEAFTLPTSFEEGKEKCPYDPARGFTGLIIDGGLYTATRYEFRSIPD 193
GT+AF P+C G +CP+D + L DG LY+AT +F +
Sbjct: 137 GTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFADGKLYSATVADFLASDA 196
Query: 194 I--RRSRHPHSLRTEETPMHWLNDAEFVFSVLVRESKASAVGDDDKVYYFFTERATEEGS 251
+ R +LRT + W+ + F+ A+ + VY+FF E A E +
Sbjct: 197 VIYRSMGDGSALRTIKYDSKWIKEPHFLH----------AIEYGNYVYFFFREIAVEHNN 246
Query: 252 -GSFTQSRSSHRVARVARVCKGDLGG-KKILQKKWTSFLKARLICHIP-----LYETLRG 304
G SR VAR+CK D+GG +++L+K WTSFLKARL C +P ++ L+
Sbjct: 247 LGKAVYSR-------VARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQS 299
Query: 305 VCSLDAETSSRTHFYAAFTLSTQWKTLEASAICRYDLAEIQAVFAGPYMEYQDGSRRWGR 364
+ + + + FT TQ ++ SA+C + + +I+ VF G + E + W
Sbjct: 300 ITDI-IQINGIPTVVGVFT--TQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTA 356
Query: 365 Y-EGGVPEPRPGSCITDSLRSQGYNSSQDLPSLVLDFVKLHPLMARPVVPTRGRPLLLKR 423
E VP+PRPG C L ++ Y +S D P L F+K HPLM V P P K
Sbjct: 357 VPEDKVPKPRPGCCAKHGL-AEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKT 415
Query: 424 NIRYTHLTGTPVTTPAGP--TYDLLFLGTADGWIHKAVVLGSGMH-----IIEETQVFRE 476
+RY LT V AGP Y ++F+G+ G + K + S ++EE + +
Sbjct: 416 RVRY-RLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNH 474
Query: 477 SQ-SVEN----LVISLL----QHSLYVGAPSGVIQLPLSSCSRYRSC-YDCILARDPYCG 526
++ S EN VISL H+LYV S +I++PLS C RY SC CI +RDPYCG
Sbjct: 475 AKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCG 534
Query: 527 W 527
W
Sbjct: 535 W 535
>gi|24234744 semaphorin 6D isoform 5 precursor [Homo sapiens]
Length = 597
Score = 221 bits (564), Expect = 2e-57
Identities = 164/541 (30%), Positives = 253/541 (46%), Gaps = 59/541 (10%)
Query: 23 LRRPSRELDATPRMTIPYEELSGTRHFKGQAQNYSTL------LLEEASARLLVGARGAL 76
LR S D P T+ Y F+G+ + L+ + L + R +
Sbjct: 18 LRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQLMLKIRDTLYIAGRDQV 77
Query: 77 FSLSANDIGDGA---HKEIHWEASPEMQSKCHQKGKNNQTECFNHVRFLQRLNSTHLYAC 133
++++ N++ +K++ W + + + C KGK+ EC N ++ N ++ C
Sbjct: 78 YTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKD-ECHNFIKVFVPRNDEMVFVC 136
Query: 134 GTHAFQPLCAAIDAEAFTLPTSFEEGKEKCPYDPARGFTGLIIDGGLYTATRYEFRSIPD 193
GT+AF P+C G +CP+D + L DG LY+AT +F +
Sbjct: 137 GTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFADGKLYSATVADFLASDA 196
Query: 194 I--RRSRHPHSLRTEETPMHWLNDAEFVFSVLVRESKASAVGDDDKVYYFFTERATEEGS 251
+ R +LRT + W+ + F+ A+ + VY+FF E A E +
Sbjct: 197 VIYRSMGDGSALRTIKYDSKWIKEPHFLH----------AIEYGNYVYFFFREIAVEHNN 246
Query: 252 -GSFTQSRSSHRVARVARVCKGDLGG-KKILQKKWTSFLKARLICHIP-----LYETLRG 304
G SR VAR+CK D+GG +++L+K WTSFLKARL C +P ++ L+
Sbjct: 247 LGKAVYSR-------VARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQS 299
Query: 305 VCSLDAETSSRTHFYAAFTLSTQWKTLEASAICRYDLAEIQAVFAGPYMEYQDGSRRWGR 364
+ + + + FT TQ ++ SA+C + + +I+ VF G + E + W
Sbjct: 300 ITDI-IQINGIPTVVGVFT--TQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTA 356
Query: 365 Y-EGGVPEPRPGSCITDSLRSQGYNSSQDLPSLVLDFVKLHPLMARPVVPTRGRPLLLKR 423
E VP+PRPG C L ++ Y +S D P L F+K HPLM V P P K
Sbjct: 357 VPEDKVPKPRPGCCAKHGL-AEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKT 415
Query: 424 NIRYTHLTGTPVTTPAGP--TYDLLFLGTADGWIHKAVVLGSGMH-----IIEETQVFRE 476
+RY LT V AGP Y ++F+G+ G + K + S ++EE + +
Sbjct: 416 RVRY-RLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNH 474
Query: 477 SQ-SVEN----LVISLL----QHSLYVGAPSGVIQLPLSSCSRYRSC-YDCILARDPYCG 526
++ S EN VISL H+LYV S +I++PLS C RY SC CI +RDPYCG
Sbjct: 475 AKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCG 534
Query: 527 W 527
W
Sbjct: 535 W 535
>gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens]
Length = 1073
Score = 221 bits (564), Expect = 2e-57
Identities = 164/541 (30%), Positives = 253/541 (46%), Gaps = 59/541 (10%)
Query: 23 LRRPSRELDATPRMTIPYEELSGTRHFKGQAQNYSTL------LLEEASARLLVGARGAL 76
LR S D P T+ Y F+G+ + L+ + L + R +
Sbjct: 18 LRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQLMLKIRDTLYIAGRDQV 77
Query: 77 FSLSANDIGDGA---HKEIHWEASPEMQSKCHQKGKNNQTECFNHVRFLQRLNSTHLYAC 133
++++ N++ +K++ W + + + C KGK+ EC N ++ N ++ C
Sbjct: 78 YTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKD-ECHNFIKVFVPRNDEMVFVC 136
Query: 134 GTHAFQPLCAAIDAEAFTLPTSFEEGKEKCPYDPARGFTGLIIDGGLYTATRYEFRSIPD 193
GT+AF P+C G +CP+D + L DG LY+AT +F +
Sbjct: 137 GTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFADGKLYSATVADFLASDA 196
Query: 194 I--RRSRHPHSLRTEETPMHWLNDAEFVFSVLVRESKASAVGDDDKVYYFFTERATEEGS 251
+ R +LRT + W+ + F+ A+ + VY+FF E A E +
Sbjct: 197 VIYRSMGDGSALRTIKYDSKWIKEPHFLH----------AIEYGNYVYFFFREIAVEHNN 246
Query: 252 -GSFTQSRSSHRVARVARVCKGDLGG-KKILQKKWTSFLKARLICHIP-----LYETLRG 304
G SR VAR+CK D+GG +++L+K WTSFLKARL C +P ++ L+
Sbjct: 247 LGKAVYSR-------VARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQS 299
Query: 305 VCSLDAETSSRTHFYAAFTLSTQWKTLEASAICRYDLAEIQAVFAGPYMEYQDGSRRWGR 364
+ + + + FT TQ ++ SA+C + + +I+ VF G + E + W
Sbjct: 300 ITDI-IQINGIPTVVGVFT--TQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTA 356
Query: 365 Y-EGGVPEPRPGSCITDSLRSQGYNSSQDLPSLVLDFVKLHPLMARPVVPTRGRPLLLKR 423
E VP+PRPG C L ++ Y +S D P L F+K HPLM V P P K
Sbjct: 357 VPEDKVPKPRPGCCAKHGL-AEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKT 415
Query: 424 NIRYTHLTGTPVTTPAGP--TYDLLFLGTADGWIHKAVVLGSGMH-----IIEETQVFRE 476
+RY LT V AGP Y ++F+G+ G + K + S ++EE + +
Sbjct: 416 RVRY-RLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNH 474
Query: 477 SQ-SVEN----LVISLL----QHSLYVGAPSGVIQLPLSSCSRYRSC-YDCILARDPYCG 526
++ S EN VISL H+LYV S +I++PLS C RY SC CI +RDPYCG
Sbjct: 475 AKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCG 534
Query: 527 W 527
W
Sbjct: 535 W 535
>gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens]
Length = 1017
Score = 221 bits (564), Expect = 2e-57
Identities = 164/541 (30%), Positives = 253/541 (46%), Gaps = 59/541 (10%)
Query: 23 LRRPSRELDATPRMTIPYEELSGTRHFKGQAQNYSTL------LLEEASARLLVGARGAL 76
LR S D P T+ Y F+G+ + L+ + L + R +
Sbjct: 18 LRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQLMLKIRDTLYIAGRDQV 77
Query: 77 FSLSANDIGDGA---HKEIHWEASPEMQSKCHQKGKNNQTECFNHVRFLQRLNSTHLYAC 133
++++ N++ +K++ W + + + C KGK+ EC N ++ N ++ C
Sbjct: 78 YTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKD-ECHNFIKVFVPRNDEMVFVC 136
Query: 134 GTHAFQPLCAAIDAEAFTLPTSFEEGKEKCPYDPARGFTGLIIDGGLYTATRYEFRSIPD 193
GT+AF P+C G +CP+D + L DG LY+AT +F +
Sbjct: 137 GTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFADGKLYSATVADFLASDA 196
Query: 194 I--RRSRHPHSLRTEETPMHWLNDAEFVFSVLVRESKASAVGDDDKVYYFFTERATEEGS 251
+ R +LRT + W+ + F+ A+ + VY+FF E A E +
Sbjct: 197 VIYRSMGDGSALRTIKYDSKWIKEPHFLH----------AIEYGNYVYFFFREIAVEHNN 246
Query: 252 -GSFTQSRSSHRVARVARVCKGDLGG-KKILQKKWTSFLKARLICHIP-----LYETLRG 304
G SR VAR+CK D+GG +++L+K WTSFLKARL C +P ++ L+
Sbjct: 247 LGKAVYSR-------VARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQS 299
Query: 305 VCSLDAETSSRTHFYAAFTLSTQWKTLEASAICRYDLAEIQAVFAGPYMEYQDGSRRWGR 364
+ + + + FT TQ ++ SA+C + + +I+ VF G + E + W
Sbjct: 300 ITDI-IQINGIPTVVGVFT--TQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTA 356
Query: 365 Y-EGGVPEPRPGSCITDSLRSQGYNSSQDLPSLVLDFVKLHPLMARPVVPTRGRPLLLKR 423
E VP+PRPG C L ++ Y +S D P L F+K HPLM V P P K
Sbjct: 357 VPEDKVPKPRPGCCAKHGL-AEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKT 415
Query: 424 NIRYTHLTGTPVTTPAGP--TYDLLFLGTADGWIHKAVVLGSGMH-----IIEETQVFRE 476
+RY LT V AGP Y ++F+G+ G + K + S ++EE + +
Sbjct: 416 RVRY-RLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNH 474
Query: 477 SQ-SVEN----LVISLL----QHSLYVGAPSGVIQLPLSSCSRYRSC-YDCILARDPYCG 526
++ S EN VISL H+LYV S +I++PLS C RY SC CI +RDPYCG
Sbjct: 475 AKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCG 534
Query: 527 W 527
W
Sbjct: 535 W 535
>gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens]
Length = 998
Score = 221 bits (564), Expect = 2e-57
Identities = 164/541 (30%), Positives = 253/541 (46%), Gaps = 59/541 (10%)
Query: 23 LRRPSRELDATPRMTIPYEELSGTRHFKGQAQNYSTL------LLEEASARLLVGARGAL 76
LR S D P T+ Y F+G+ + L+ + L + R +
Sbjct: 18 LRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQLMLKIRDTLYIAGRDQV 77
Query: 77 FSLSANDIGDGA---HKEIHWEASPEMQSKCHQKGKNNQTECFNHVRFLQRLNSTHLYAC 133
++++ N++ +K++ W + + + C KGK+ EC N ++ N ++ C
Sbjct: 78 YTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKD-ECHNFIKVFVPRNDEMVFVC 136
Query: 134 GTHAFQPLCAAIDAEAFTLPTSFEEGKEKCPYDPARGFTGLIIDGGLYTATRYEFRSIPD 193
GT+AF P+C G +CP+D + L DG LY+AT +F +
Sbjct: 137 GTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFADGKLYSATVADFLASDA 196
Query: 194 I--RRSRHPHSLRTEETPMHWLNDAEFVFSVLVRESKASAVGDDDKVYYFFTERATEEGS 251
+ R +LRT + W+ + F+ A+ + VY+FF E A E +
Sbjct: 197 VIYRSMGDGSALRTIKYDSKWIKEPHFLH----------AIEYGNYVYFFFREIAVEHNN 246
Query: 252 -GSFTQSRSSHRVARVARVCKGDLGG-KKILQKKWTSFLKARLICHIP-----LYETLRG 304
G SR VAR+CK D+GG +++L+K WTSFLKARL C +P ++ L+
Sbjct: 247 LGKAVYSR-------VARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQS 299
Query: 305 VCSLDAETSSRTHFYAAFTLSTQWKTLEASAICRYDLAEIQAVFAGPYMEYQDGSRRWGR 364
+ + + + FT TQ ++ SA+C + + +I+ VF G + E + W
Sbjct: 300 ITDI-IQINGIPTVVGVFT--TQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTA 356
Query: 365 Y-EGGVPEPRPGSCITDSLRSQGYNSSQDLPSLVLDFVKLHPLMARPVVPTRGRPLLLKR 423
E VP+PRPG C L ++ Y +S D P L F+K HPLM V P P K
Sbjct: 357 VPEDKVPKPRPGCCAKHGL-AEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKT 415
Query: 424 NIRYTHLTGTPVTTPAGP--TYDLLFLGTADGWIHKAVVLGSGMH-----IIEETQVFRE 476
+RY LT V AGP Y ++F+G+ G + K + S ++EE + +
Sbjct: 416 RVRY-RLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNH 474
Query: 477 SQ-SVEN----LVISLL----QHSLYVGAPSGVIQLPLSSCSRYRSC-YDCILARDPYCG 526
++ S EN VISL H+LYV S +I++PLS C RY SC CI +RDPYCG
Sbjct: 475 AKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCG 534
Query: 527 W 527
W
Sbjct: 535 W 535
>gi|19718780 semaphorin 6B precursor [Homo sapiens]
Length = 888
Score = 212 bits (539), Expect = 1e-54
Identities = 160/500 (32%), Positives = 234/500 (46%), Gaps = 68/500 (13%)
Query: 90 KEIHWEASPEMQSKCHQKGKNNQTECFNHVRFLQRLNSTHLYACGTHAFQPLCAAIDAEA 149
+++ W ++P + C KGK + EC N V+ L + + L+ CG++AF P+CA +
Sbjct: 102 RKLTWRSNPSDINVCRMKGKQ-EGECRNFVKVLLLRDESTLFVCGSNAFNPVCANYSIDT 160
Query: 150 FTLPTSFEEGKEKCPYDPARGFTGLIIDGGLYTATRYEFRSIPDI--RRSRHPHSLRTEE 207
G +CPYDP L DG L+TAT +F +I + R +LRT +
Sbjct: 161 LQPVGDNISGMARCPYDPKHANVALFSDGMLFTATVTDFLAIDAVIYRSLGDRPTLRTVK 220
Query: 208 TPMHWLNDAEFVFSVLVRESKASAVGDDDKVYYFFTERATEEGSGSFTQSRSSHRVARVA 267
W + FV AV VY+FF E A E V+RVA
Sbjct: 221 HDSKWFKEPYFVH----------AVEWGSHVYFFFREIAME------FNYLEKVVVSRVA 264
Query: 268 RVCKGDLGGK-KILQKKWTSFLKARLICHIP--------LYETLRGVCSLDAETSSRTHF 318
RVCK D+GG ++L+K+WTSFLKARL C +P + + + GV SL R
Sbjct: 265 RVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSHFYFNVLQAVTGVVSL----GGRPVV 320
Query: 319 YAAFTLSTQWKTLEASAICRYDLAEIQAVFAGPYMEYQDGSRRWGRY-EGGVPEPRPGSC 377
A F ST ++ SA+C +DL ++ AVF G + E + W E VP PRPG C
Sbjct: 321 LAVF--STPSNSIPGSAVCAFDLTQVAAVFEGRFREQKSPESIWTPVPEDQVPRPRPGCC 378
Query: 378 ITDSLRSQGYNSSQDLPSLVLDFVKLHPLMARPVVPTRGRPLLLKRNIRYTHLTGTPVTT 437
++ YN+S LP +L+FVK HPLM VP+ G + R + LT V
Sbjct: 379 AAPGMQ---YNASSALPDDILNFVKTHPLMDE-AVPSLGHAPWILRTLMRHQLTRVAVDV 434
Query: 438 PAGP--TYDLLFLGTADGWIHKAVVL-------GSGMHI-IEETQVFR-----------E 476
AGP ++FLG+ G + K +V SG+ + +EE + +R
Sbjct: 435 GAGPWGNQTVVFLGSEAGTVLKFLVRPNASTSGTSGLSVFLEEFETYRPDRCGRPGGGET 494
Query: 477 SQSVENLVISLLQHSLYVGAPSGVIQLPLSSCSRYRSCY-DCILARDPYCGWDPGTHACA 535
Q + +L + L P V+++P++ C +Y C +CI ++DPYCGW P
Sbjct: 495 GQRLLSLELDAASGGLLAAFPRCVVRVPVARCQQYSGCMKNCIGSQDPYCGWAPDGSCIF 554
Query: 536 AATTIANRSQGSRTALIQDI 555
S G+R A QD+
Sbjct: 555 L-------SPGTRAAFEQDV 567
>gi|16306552 semaphorin Y [Homo sapiens]
Length = 930
Score = 205 bits (521), Expect = 2e-52
Identities = 156/491 (31%), Positives = 235/491 (47%), Gaps = 55/491 (11%)
Query: 68 LLVGARGALFS--LSANDIGDGA--HKEIHWEASPEMQSKCHQKGKNNQTECFNHVRFLQ 123
LLV AR +FS L A + G+G +K + W + C +GK EC+N++R L
Sbjct: 73 LLVAARDHVFSFDLQAEEEGEGLVPNKYLTWRSQDV--ENCAVRGKLTD-ECYNYIRVLV 129
Query: 124 RLNSTHLYACGTHAFQPLCAAIDAEAFTLPTSFEEGKEKCPYDPARGFTGLIIDGGLYTA 183
+S L ACGT++F P+C + + G+ +CP+D + + +G LY+A
Sbjct: 130 PWDSQTLLACGTNSFSPVCRSYGITSLQQEGEELSGQARCPFDATQSNVAIFAEGSLYSA 189
Query: 184 TRYEFR-SIPDIRRSRHPH-SLRTEETPMHWLNDAEFVFSVLVRESKASAVGDDDKVYYF 241
T +F+ S + RS P LR+ + WL + FV A+ D VY+F
Sbjct: 190 TAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFV----------QALEHGDHVYFF 239
Query: 242 FTERATEEGSGSFTQSRSSHRVARVARVCKGDLGGK-KILQKKWTSFLKARLICHIP--- 297
F E + E+ Q +RVARVCK D+GG + L + WTSFLK RL C +P
Sbjct: 240 FREVSVEDARLGRVQ------FSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDS 293
Query: 298 -LYETLRGVCSLDAETSSRTHFYAAFTLSTQWKTLEASAICRYDLAEIQAVFAGPYMEYQ 356
Y + + R+ + FT TQ ++ SA+C + L EI+ F G + E +
Sbjct: 294 TFYFDVLQALTGPVNLHGRSALFGVFT--TQTNSIPGSAVCAFYLDEIERGFEGKFKEQR 351
Query: 357 DGSRRWGRY-EGGVPEPRPGSCITDSLRSQGYNSSQDLPSLVLDFVKLHPLMARPVVPTR 415
W E VP PRPGSC + ++SS+DLP VL F+K HPL+ V P
Sbjct: 352 SLDGAWTPVSEDRVPSPRPGSCAGVG-GAALFSSSRDLPDDVLTFIKAHPLLDPAVPPVT 410
Query: 416 GRPLLLKRNIRYTHLTGTPVTTPAGP--TYDLLFLGTADGWIHKAVVLGSGMH-----II 468
+PLL + LT V AGP ++FLG+ DG + K + G ++
Sbjct: 411 HQPLLTLTS--RALLTQVAVDGMAGPHSNITVMFLGSNDGTVLKVLTPGGRSGGPEPILL 468
Query: 469 EETQVF--------RESQSVENLV---ISLLQHSLYVGAPSGVIQLPLSSCSRYRSCY-D 516
EE + R +Q+ ++ + H L+V ++ LPLS C+R+ +C
Sbjct: 469 EEIDAYSPARCSGKRTAQTARRIIGLELDTEGHRLFVAFSGCIVYLPLSRCARHGACQRS 528
Query: 517 CILARDPYCGW 527
C+ ++DPYCGW
Sbjct: 529 CLASQDPYCGW 539
>gi|91982767 semaphorin 5B isoform 1 [Homo sapiens]
Length = 1151
Score = 201 bits (511), Expect = 2e-51
Identities = 159/505 (31%), Positives = 236/505 (46%), Gaps = 48/505 (9%)
Query: 53 AQNYSTLLLEEASARLLVGARGALFSLSANDIGDGAHKEIHWEASPEMQSKCHQKGKNNQ 112
A+++S L L+ + +L+VGAR LF LS ++ + W +S + + C KGK +
Sbjct: 123 ARDFSQLALDPSGNQLIVGARNYLFRLSLANVS--LLQATEWASSEDTRRSCQSKGKTEE 180
Query: 113 TECFNHVRFLQRLNSTHLYACGTHAFQPLCAAIDAEAFTLPTSFEEGKEKCPYDPARGFT 172
EC N+VR L + ++ CGT+AF P+C + + G +CPYDP T
Sbjct: 181 -ECQNYVRVLI-VAGRKVFMCGTNAFSPMCTSRQVGNLSRTIEKINGVARCPYDPRHNST 238
Query: 173 GLIIDGG-LYTATRYEFRSI-PDIRRSRHPHS-LRTEETPMHWLNDAEFVFSVLVRESKA 229
+I G LY AT +F P I RS LRT + WLN+ FV
Sbjct: 239 AVISSQGELYAATVIDFSGRDPAIYRSLGSGPPLRTAQYNSKWLNEPNFV---------- 288
Query: 230 SAVGDDDKVYYFFTERATEEGSGSFTQSRSSHRVARVARVCKGDLGGKKILQKKWTSFLK 289
+A Y+F E A E G SR VARVCK D+GG+ +L+ WT+F+K
Sbjct: 289 AAYDIGLFAYFFLRENAVEHDCGRTVYSR-------VARVCKNDVGGRFLLEDTWTTFMK 341
Query: 290 ARLICHIP-----LYETLRGVCSLDAETSSRTHFYAAFTLSTQWKTLEASAICRYDLAEI 344
ARL C P Y L+ L + Y FT T ++ ASA+C ++L+ I
Sbjct: 342 ARLNCSRPGEVPFYYNELQSAFHLPEQDL----IYGVFT--TNVNSIAASAVCAFNLSAI 395
Query: 345 QAVFAGPYMEYQDGSRRWGRYEGGVPEPRPGSCITDSLRSQGYNSSQDLPSLVLDFVKLH 404
F GP+ ++ W +P + G+ L G N + SL D +L
Sbjct: 396 SQAFNGPFRYQENPRAAWLPIANPIPNFQCGT-----LPETGPNENLTERSLQ-DAQRLF 449
Query: 405 PLMARPVVPTRGRPLLLKRNIRYTHLTGTPVTTPAGPTYDLLFLGTADGWIHKAVVLGS- 463
LM+ V P P + + ++R++HL + Y +L++GT G I KA+ S
Sbjct: 450 -LMSEAVQPVTPEPCVTQDSVRFSHLV-VDLVQAKDTLYHVLYIGTESGTILKALSTASR 507
Query: 464 GMH--IIEETQVFRES--QSVENLVISLLQHSLYVGAPSGVIQLPLSSCSRYRSCYDCIL 519
+H +EE V + + +L I +L+VG GV+++PL C+ YRS C+
Sbjct: 508 SLHGCYLEELHVLPPGRREPLRSLRILHSARALFVGLRDGVLRVPLERCAAYRSQGACLG 567
Query: 520 ARDPYCGWDPGTHACAAATTIANRS 544
ARDPYCGWD C+ +N S
Sbjct: 568 ARDPYCGWDGKQQRCSTLEDSSNMS 592
>gi|147904700 semaphorin 5A [Homo sapiens]
Length = 1074
Score = 197 bits (501), Expect = 3e-50
Identities = 162/519 (31%), Positives = 234/519 (45%), Gaps = 51/519 (9%)
Query: 33 TPRMTIPYEELSG-TRHFKGQ-AQNYSTLLLEEASARLLVGARGALFSLSANDIGDGAHK 90
T I Y+E+ R F+ + A ++S L + L+VGAR LF L D+ +
Sbjct: 33 TEHPVISYKEIGPWLREFRAKNAVDFSQLTFDPGQKELVVGARNYLFRLQLEDLS--LIQ 90
Query: 91 EIHWEASPEMQSKCHQKGKNNQTECFNHVRFLQRLNSTHLYACGTHAFQPLCAAIDAEAF 150
+ WE + C+ KGK+ + EC N++R L + L+ CGT+AF P+C
Sbjct: 91 AVEWECDEATKKACYSKGKSKE-ECQNYIRVLL-VGGDRLFTCGTNAFTPVCTNRSLSNL 148
Query: 151 TLPTSFEEGKEKCPYDPARGFTGLIIDGG-LYTATRYEFRSI-PDIRRSRHP-HSLRTEE 207
T G +CPY P T L+ GG LY AT +F P I RS LRT +
Sbjct: 149 TEIHDQISGMARCPYSPQHNSTALLTAGGELYAATAMDFPGRDPAIYRSLGILPPLRTAQ 208
Query: 208 TPMHWLNDAEFVFSVLVRESKASAVGDDDKVYYFFTERATEEGSGSFTQSRSSHRVARVA 267
WLN+ FV S + + Y+FF E A E G SR+ A
Sbjct: 209 YNSKWLNEPNFVSSYDI----------GNFTYFFFRENAVEHDCGKTVFSRA-------A 251
Query: 268 RVCKGDLGGKKILQKKWTSFLKARLICHIP-----LYETLRGVCSLDAETSSRTHFYAAF 322
RVCK D+GG+ +L+ WT+F+KARL C P Y L+ L Y F
Sbjct: 252 RVCKNDIGGRFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSTFFLP----ELDLIYGIF 307
Query: 323 TLSTQWKTLEASAICRYDLAEIQAVFAGPYMEYQDGSRRWGRYEGGVPEPRPGSCITDSL 382
T T ++ ASA+C ++L+ I F+GP+ +YQ+ SR +P P P
Sbjct: 308 T--TNVNSIAASAVCVFNLSAIAQAFSGPF-KYQENSR-----SAWLPYPNPNPHFQCGT 359
Query: 383 RSQGYNSSQDLPSLVLDFVKLHPLMARPVVPTRGRPLLLKRNIRYTHLTGTPVTTPAGPT 442
QG + L L + LM V P P ++ N R++H+ V
Sbjct: 360 VDQGLYVN--LTERNLQDAQKFILMHEVVQPVTTVPSFMEDNSRFSHVA-VDVVQGREAL 416
Query: 443 YDLLFLGTADGWIHKAVV---LGSGMHIIEETQVF--RESQSVENLVISLLQHSLYVGAP 497
+++L T G I K V S ++EE ++F R + + +L I Q L+VG
Sbjct: 417 VHIIYLATDYGTIKKVRVPLNQTSSSCLLEEIELFPERRREPIRSLQILHSQSVLFVGLR 476
Query: 498 SGVIQLPLSSCSRYRSCYDCILARDPYCGWDPGTHACAA 536
V+++PL C YR+ CI A+DPYCGWD C +
Sbjct: 477 EHVVKIPLKRCQFYRTRSTCIGAQDPYCGWDVVMKKCTS 515
>gi|24234732 semaphorin 6D isoform 6 precursor [Homo sapiens]
Length = 476
Score = 178 bits (451), Expect = 2e-44
Identities = 134/482 (27%), Positives = 218/482 (45%), Gaps = 49/482 (10%)
Query: 23 LRRPSRELDATPRMTIPYEELSGTRHFKGQAQNYSTL------LLEEASARLLVGARGAL 76
LR S D P T+ Y F+G+ + L+ + L + R +
Sbjct: 18 LRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQLMLKIRDTLYIAGRDQV 77
Query: 77 FSLSANDIGDGA---HKEIHWEASPEMQSKCHQKGKNNQTECFNHVRFLQRLNSTHLYAC 133
++++ N++ +K++ W + + + C KGK+ EC N ++ N ++ C
Sbjct: 78 YTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKD-ECHNFIKVFVPRNDEMVFVC 136
Query: 134 GTHAFQPLCAAIDAEAFTLPTSFEEGKEKCPYDPARGFTGLIIDGGLYTATRYEFRSIPD 193
GT+AF P+C G +CP+D + L DG LY+AT +F +
Sbjct: 137 GTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFADGKLYSATVADFLASDA 196
Query: 194 I--RRSRHPHSLRTEETPMHWLNDAEFVFSVLVRESKASAVGDDDKVYYFFTERATEEGS 251
+ R +LRT + W+ + F+ A+ + VY+FF E A E +
Sbjct: 197 VIYRSMGDGSALRTIKYDSKWIKEPHFLH----------AIEYGNYVYFFFREIAVEHNN 246
Query: 252 -GSFTQSRSSHRVARVARVCKGDLGG-KKILQKKWTSFLKARLICHIP-----LYETLRG 304
G SR VAR+CK D+GG +++L+K WTSFLKARL C +P ++ L+
Sbjct: 247 LGKAVYSR-------VARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQS 299
Query: 305 VCSLDAETSSRTHFYAAFTLSTQWKTLEASAICRYDLAEIQAVFAGPYMEYQDGSRRWGR 364
+ + + + FT TQ ++ SA+C + + +I+ VF G + E + W
Sbjct: 300 ITDI-IQINGIPTVVGVFT--TQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTA 356
Query: 365 Y-EGGVPEPRPGSCITDSLRSQGYNSSQDLPSLVLDFVKLHPLMARPVVPTRGRPLLLKR 423
E VP+PRPG C L ++ Y +S D P L F+K HPLM V P P K
Sbjct: 357 VPEDKVPKPRPGCCAKHGL-AEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKT 415
Query: 424 NIRYTHLTGTPVTTPAGP--TYDLLFLGTADGWIHKAVVLGSGMH-----IIEETQVFRE 476
+RY LT V AGP Y ++F+G+ G + K + S ++EE + +
Sbjct: 416 RVRY-RLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNH 474
Query: 477 SQ 478
++
Sbjct: 475 AK 476
>gi|4504237 semaphorin 7A isoform 1 preproprotein [Homo sapiens]
Length = 666
Score = 173 bits (439), Expect = 5e-43
Identities = 162/606 (26%), Positives = 253/606 (41%), Gaps = 73/606 (12%)
Query: 51 GQAQNYSTLLLEEASARLLVGARGALFSLSANDIGDGAHKEIHWEASPEMQSKCHQKGKN 110
GQ + ++ L E S+ + VG RG ++ D +G + + + C K
Sbjct: 70 GQTEPHTVLFHEPGSSSVWVGGRGKVYLF---DFPEGKNASVRTVNIGSTKGSCLDK--- 123
Query: 111 NQTECFNHVRFLQRLNSTHLYACGTHAFQPLCAAIDAEAFTLPTSFEEGKEKCPYDPARG 170
+C N++ L+R S L ACGT+A P C + +P E + P+ P
Sbjct: 124 --RDCENYITLLER-RSEGLLACGTNARHPSCWNL-VNGTVVPLG--EMRGYAPFSPDEN 177
Query: 171 FTGLIIDGGLYTATRYEFRS--IPDIRRSRHPHSLRTEETPMHWLNDAEFVFSVLVRESK 228
L +Y+ R + + IP RR R L T +T M + +F+ + +V + +
Sbjct: 178 SLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQ---NPQFIKATIVHQDQ 234
Query: 229 ASAVGDDDKVYYFFTERATEEGSGSFTQSRSSHRVARVARVCKGDLGGKKILQ-KKWTSF 287
A DDK+YYFF E ++ + V+RVA++C+GD GG+ L KW +F
Sbjct: 235 AY----DDKIYYFFREDNPDKNP------EAPLNVSRVAQLCRGDQGGESSLSVSKWNTF 284
Query: 288 LKARLICHIPL----YETLRGVCSLDAETSS--RTHFYAAFTLSTQWKTLEASAICRYDL 341
LKA L+C + L+ V L + T Y F S W SA+C Y L
Sbjct: 285 LKAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVF--SNPWNY---SAVCVYSL 339
Query: 342 AEIQAVFAGPYMEYQDGSRRWGRYEGGVPEPRPGSCITDSLRSQGYNSSQDLPSLVLDFV 401
+I VF ++ Y +P PRPG C+ D Q +P+
Sbjct: 340 GDIDKVFRTSSLK---------GYHSSLPNPRPGKCLPDQ---------QPIPTETFQVA 381
Query: 402 KLHPLMARPVVPTRG-RPLLLKRNIRYTHLTGTPVTTPAGPTYDLLFLGTADGWIHKAVV 460
HP +A+ V P + L Y + + G T+ +L+L T G IHK V
Sbjct: 382 DRHPEVAQRVEPMGPLKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVE 441
Query: 461 LGSGMHI----IEETQVFRESQSVENLVISLLQHSLYVGAPSGVIQLPLSSCSRYRS-CY 515
G H I E Q FR + +++ + + + LYV + V Q+PL C Y C+
Sbjct: 442 PGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCH 501
Query: 516 DCILARDPYCGWDPGTHACAAATTIANRSQGSRTALIQDIERGNRGCESSRDTGPPPPLK 575
C+++RDPYCGWD G C + S +++Q I E PL+
Sbjct: 502 GCLMSRDPYCGWDQG--RCISI-------YSSERSVLQSINPAEPHKECPNPKPDKAPLQ 552
Query: 576 TRSVLRGDDVLLPCDQPSNLARALWLLNGSMGLSDGQGGYRVGVDGLLVTDAQPEHSGNY 635
S+ L C S A W ++ S + G++ L + + + G+Y
Sbjct: 553 KVSLAPNSRYYLSCPMESRHATYSWRHKENVEQS-CEPGHQSPNCILFIENLTAQQYGHY 611
Query: 636 GCYAEE 641
C A+E
Sbjct: 612 FCEAQE 617
>gi|225637520 semaphorin 7A isoform 2 preproprotein [Homo sapiens]
Length = 652
Score = 170 bits (431), Expect = 4e-42
Identities = 161/606 (26%), Positives = 252/606 (41%), Gaps = 87/606 (14%)
Query: 51 GQAQNYSTLLLEEASARLLVGARGALFSLSANDIGDGAHKEIHWEASPEMQSKCHQKGKN 110
GQ + ++ L E S+ + VG RG ++ D +G + +
Sbjct: 70 GQTEPHTVLFHEPGSSSVWVGGRGKVYLF---DFPEGKNASV------------------ 108
Query: 111 NQTECFNHVRFLQRLNSTHLYACGTHAFQPLCAAIDAEAFTLPTSFEEGKEKCPYDPARG 170
+T+C N++ L+R S L ACGT+A P C + +P E + P+ P
Sbjct: 109 -RTDCENYITLLER-RSEGLLACGTNARHPSCWNL-VNGTVVPLG--EMRGYAPFSPDEN 163
Query: 171 FTGLIIDGGLYTATRYEFRS--IPDIRRSRHPHSLRTEETPMHWLNDAEFVFSVLVRESK 228
L +Y+ R + + IP RR R L T +T M + +F+ + +V + +
Sbjct: 164 SLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQ---NPQFIKATIVHQDQ 220
Query: 229 ASAVGDDDKVYYFFTERATEEGSGSFTQSRSSHRVARVARVCKGDLGGKKILQ-KKWTSF 287
A DDK+YYFF E ++ + V+RVA++C+GD GG+ L KW +F
Sbjct: 221 AY----DDKIYYFFREDNPDKNP------EAPLNVSRVAQLCRGDQGGESSLSVSKWNTF 270
Query: 288 LKARLICHIPL----YETLRGVCSLDAETSS--RTHFYAAFTLSTQWKTLEASAICRYDL 341
LKA L+C + L+ V L + T Y F S W SA+C Y L
Sbjct: 271 LKAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVF--SNPWNY---SAVCVYSL 325
Query: 342 AEIQAVFAGPYMEYQDGSRRWGRYEGGVPEPRPGSCITDSLRSQGYNSSQDLPSLVLDFV 401
+I VF ++ Y +P PRPG C+ D Q +P+
Sbjct: 326 GDIDKVFRTSSLK---------GYHSSLPNPRPGKCLPDQ---------QPIPTETFQVA 367
Query: 402 KLHPLMARPVVPTRG-RPLLLKRNIRYTHLTGTPVTTPAGPTYDLLFLGTADGWIHKAVV 460
HP +A+ V P + L Y + + G T+ +L+L T G IHK V
Sbjct: 368 DRHPEVAQRVEPMGPLKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVE 427
Query: 461 LGSGMHI----IEETQVFRESQSVENLVISLLQHSLYVGAPSGVIQLPLSSCSRYRS-CY 515
G H I E Q FR + +++ + + + LYV + V Q+PL C Y C+
Sbjct: 428 PGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCH 487
Query: 516 DCILARDPYCGWDPGTHACAAATTIANRSQGSRTALIQDIERGNRGCESSRDTGPPPPLK 575
C+++RDPYCGWD G C + S +++Q I E PL+
Sbjct: 488 GCLMSRDPYCGWDQG--RCISI-------YSSERSVLQSINPAEPHKECPNPKPDKAPLQ 538
Query: 576 TRSVLRGDDVLLPCDQPSNLARALWLLNGSMGLSDGQGGYRVGVDGLLVTDAQPEHSGNY 635
S+ L C S A W ++ S + G++ L + + + G+Y
Sbjct: 539 KVSLAPNSRYYLSCPMESRHATYSWRHKENVEQS-CEPGHQSPNCILFIENLTAQQYGHY 597
Query: 636 GCYAEE 641
C A+E
Sbjct: 598 FCEAQE 603
>gi|225637524 semaphorin 7A isoform 3 [Homo sapiens]
Length = 501
Score = 148 bits (373), Expect = 2e-35
Identities = 134/493 (27%), Positives = 206/493 (41%), Gaps = 61/493 (12%)
Query: 164 PYDPARGFTGLIIDGGLYTATRYEFRS--IPDIRRSRHPHSLRTEETPMHWLNDAEFVFS 221
P+ P L +Y+ R + + IP RR R L T +T M + +F+ +
Sbjct: 6 PFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQ---NPQFIKA 62
Query: 222 VLVRESKASAVGDDDKVYYFFTERATEEGSGSFTQSRSSHRVARVARVCKGDLGGKKILQ 281
+V + +A DDK+YYFF E ++ + V+RVA++C+GD GG+ L
Sbjct: 63 TIVHQDQAY----DDKIYYFFREDNPDKNP------EAPLNVSRVAQLCRGDQGGESSLS 112
Query: 282 -KKWTSFLKARLICHIPL----YETLRGVCSLDAETSS--RTHFYAAFTLSTQWKTLEAS 334
KW +FLKA L+C + L+ V L + T Y F S W S
Sbjct: 113 VSKWNTFLKAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVF--SNPWNY---S 167
Query: 335 AICRYDLAEIQAVFAGPYMEYQDGSRRWGRYEGGVPEPRPGSCITDSLRSQGYNSSQDLP 394
A+C Y L +I VF ++ Y +P PRPG C+ D Q +P
Sbjct: 168 AVCVYSLGDIDKVFRTSSLK---------GYHSSLPNPRPGKCLPDQ---------QPIP 209
Query: 395 SLVLDFVKLHPLMARPVVPTRG-RPLLLKRNIRYTHLTGTPVTTPAGPTYDLLFLGTADG 453
+ HP +A+ V P + L Y + + G T+ +L+L T G
Sbjct: 210 TETFQVADRHPEVAQRVEPMGPLKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTTDRG 269
Query: 454 WIHKAVVLGSGMHI----IEETQVFRESQSVENLVISLLQHSLYVGAPSGVIQLPLSSCS 509
IHK V G H I E Q FR + +++ + + + LYV + V Q+PL C
Sbjct: 270 TIHKVVEPGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCE 329
Query: 510 RYRS-CYDCILARDPYCGWDPGTHACAAATTIANRSQGSRTALIQDIERGNRGCESSRDT 568
Y C+ C+++RDPYCGWD G C + S +++Q I E
Sbjct: 330 VYGGGCHGCLMSRDPYCGWDQG--RCISI-------YSSERSVLQSINPAEPHKECPNPK 380
Query: 569 GPPPPLKTRSVLRGDDVLLPCDQPSNLARALWLLNGSMGLSDGQGGYRVGVDGLLVTDAQ 628
PL+ S+ L C S A W ++ S + G++ L + +
Sbjct: 381 PDKAPLQKVSLAPNSRYYLSCPMESRHATYSWRHKENVEQS-CEPGHQSPNCILFIENLT 439
Query: 629 PEHSGNYGCYAEE 641
+ G+Y C A+E
Sbjct: 440 AQQYGHYFCEAQE 452
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,541,771
Number of Sequences: 37866
Number of extensions: 2135944
Number of successful extensions: 29950
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 387
Number of HSP's successfully gapped in prelim test: 262
Number of HSP's that attempted gapping in prelim test: 20235
Number of HSP's gapped (non-prelim): 6314
length of query: 843
length of database: 18,247,518
effective HSP length: 111
effective length of query: 732
effective length of database: 14,044,392
effective search space: 10280494944
effective search space used: 10280494944
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.