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Search of human proteins with 28559027
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|28559027 interleukin 5 receptor, alpha isoform 1 precursor
[Homo sapiens]
(420 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|28559021 interleukin 5 receptor, alpha isoform 1 precursor [H... 860 0.0
gi|28559027 interleukin 5 receptor, alpha isoform 1 precursor [H... 860 0.0
gi|28559023 interleukin 5 receptor, alpha isoform 2 precursor [H... 681 0.0
gi|28559025 interleukin 5 receptor, alpha isoform 3 precursor [H... 681 0.0
gi|28559031 interleukin 5 receptor, alpha isoform 3 precursor [H... 681 0.0
gi|28559029 interleukin 5 receptor, alpha isoform 2 precursor [H... 681 0.0
gi|10834992 interleukin 13 receptor, alpha 2 precursor [Homo sap... 111 1e-24
gi|4504647 interleukin 13 receptor, alpha 1 precursor [Homo sapi... 100 2e-21
gi|20070195 colony stimulating factor 2 receptor alpha chain iso... 97 3e-20
gi|238908519 colony stimulating factor 2 receptor alpha chain is... 97 3e-20
gi|238908515 colony stimulating factor 2 receptor alpha chain is... 97 3e-20
gi|27437032 colony stimulating factor 2 receptor alpha chain iso... 97 3e-20
gi|238908521 colony stimulating factor 2 receptor alpha chain is... 95 1e-19
gi|238908517 colony stimulating factor 2 receptor alpha chain is... 83 5e-16
gi|27437036 colony stimulating factor 2 receptor alpha chain iso... 83 5e-16
gi|13324710 interleukin 3 receptor, alpha precursor [Homo sapiens] 82 1e-15
gi|27437034 colony stimulating factor 2 receptor alpha chain iso... 81 2e-15
gi|4506107 prolactin receptor [Homo sapiens] 55 2e-07
gi|4557882 interleukin 2 receptor, gamma precursor [Homo sapiens] 52 8e-07
gi|27437040 colony stimulating factor 2 receptor alpha chain iso... 49 1e-05
gi|4503591 erythropoietin receptor precursor [Homo sapiens] 47 2e-05
gi|4503993 growth hormone receptor precursor [Homo sapiens] 44 2e-04
gi|31083174 interleukin 21 receptor precursor [Homo sapiens] 42 8e-04
gi|11141869 interleukin 21 receptor precursor [Homo sapiens] 42 8e-04
gi|31083180 interleukin 21 receptor precursor [Homo sapiens] 42 8e-04
gi|4559408 colony stimulating factor 2 receptor, beta precursor ... 40 0.003
gi|4885491 myeloproliferative leukemia virus oncogene precursor ... 40 0.005
gi|4758062 cytokine receptor-like factor 1 [Homo sapiens] 40 0.005
gi|51093381 leptin receptor isoform 3 [Homo sapiens] 39 0.009
gi|51093379 leptin receptor isoform 2 [Homo sapiens] 39 0.009
>gi|28559021 interleukin 5 receptor, alpha isoform 1 precursor [Homo
sapiens]
Length = 420
Score = 860 bits (2223), Expect = 0.0
Identities = 420/420 (100%), Positives = 420/420 (100%)
Query: 1 MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRN 60
MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRN
Sbjct: 1 MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRN 60
Query: 61 VNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHA 120
VNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHA
Sbjct: 61 VNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHA 120
Query: 121 PPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE 180
PPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE
Sbjct: 121 PPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE 180
Query: 181 ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN 240
ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN
Sbjct: 181 ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN 240
Query: 241 PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD 300
PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD
Sbjct: 241 PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD 300
Query: 301 LSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGNDEHKPLREWFVIVIMATICFILLILSL 360
LSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGNDEHKPLREWFVIVIMATICFILLILSL
Sbjct: 301 LSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGNDEHKPLREWFVIVIMATICFILLILSL 360
Query: 361 ICKICHLWIKLFPPIPAPKSNIKDLFVTTNYEKAGSSETEIEVICYIEKPGVETLEDSVF 420
ICKICHLWIKLFPPIPAPKSNIKDLFVTTNYEKAGSSETEIEVICYIEKPGVETLEDSVF
Sbjct: 361 ICKICHLWIKLFPPIPAPKSNIKDLFVTTNYEKAGSSETEIEVICYIEKPGVETLEDSVF 420
>gi|28559027 interleukin 5 receptor, alpha isoform 1 precursor [Homo
sapiens]
Length = 420
Score = 860 bits (2223), Expect = 0.0
Identities = 420/420 (100%), Positives = 420/420 (100%)
Query: 1 MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRN 60
MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRN
Sbjct: 1 MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRN 60
Query: 61 VNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHA 120
VNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHA
Sbjct: 61 VNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHA 120
Query: 121 PPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE 180
PPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE
Sbjct: 121 PPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE 180
Query: 181 ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN 240
ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN
Sbjct: 181 ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN 240
Query: 241 PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD 300
PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD
Sbjct: 241 PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD 300
Query: 301 LSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGNDEHKPLREWFVIVIMATICFILLILSL 360
LSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGNDEHKPLREWFVIVIMATICFILLILSL
Sbjct: 301 LSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGNDEHKPLREWFVIVIMATICFILLILSL 360
Query: 361 ICKICHLWIKLFPPIPAPKSNIKDLFVTTNYEKAGSSETEIEVICYIEKPGVETLEDSVF 420
ICKICHLWIKLFPPIPAPKSNIKDLFVTTNYEKAGSSETEIEVICYIEKPGVETLEDSVF
Sbjct: 361 ICKICHLWIKLFPPIPAPKSNIKDLFVTTNYEKAGSSETEIEVICYIEKPGVETLEDSVF 420
>gi|28559023 interleukin 5 receptor, alpha isoform 2 precursor [Homo
sapiens]
Length = 333
Score = 681 bits (1756), Expect = 0.0
Identities = 332/332 (100%), Positives = 332/332 (100%)
Query: 1 MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRN 60
MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRN
Sbjct: 1 MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRN 60
Query: 61 VNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHA 120
VNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHA
Sbjct: 61 VNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHA 120
Query: 121 PPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE 180
PPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE
Sbjct: 121 PPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE 180
Query: 181 ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN 240
ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN
Sbjct: 181 ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN 240
Query: 241 PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD 300
PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD
Sbjct: 241 PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD 300
Query: 301 LSKYDVQVRAAVSSMCREAGLWSEWSQPIYVG 332
LSKYDVQVRAAVSSMCREAGLWSEWSQPIYVG
Sbjct: 301 LSKYDVQVRAAVSSMCREAGLWSEWSQPIYVG 332
>gi|28559025 interleukin 5 receptor, alpha isoform 3 precursor [Homo
sapiens]
Length = 335
Score = 681 bits (1756), Expect = 0.0
Identities = 332/332 (100%), Positives = 332/332 (100%)
Query: 1 MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRN 60
MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRN
Sbjct: 1 MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRN 60
Query: 61 VNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHA 120
VNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHA
Sbjct: 61 VNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHA 120
Query: 121 PPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE 180
PPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE
Sbjct: 121 PPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE 180
Query: 181 ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN 240
ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN
Sbjct: 181 ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN 240
Query: 241 PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD 300
PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD
Sbjct: 241 PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD 300
Query: 301 LSKYDVQVRAAVSSMCREAGLWSEWSQPIYVG 332
LSKYDVQVRAAVSSMCREAGLWSEWSQPIYVG
Sbjct: 301 LSKYDVQVRAAVSSMCREAGLWSEWSQPIYVG 332
>gi|28559031 interleukin 5 receptor, alpha isoform 3 precursor [Homo
sapiens]
Length = 335
Score = 681 bits (1756), Expect = 0.0
Identities = 332/332 (100%), Positives = 332/332 (100%)
Query: 1 MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRN 60
MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRN
Sbjct: 1 MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRN 60
Query: 61 VNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHA 120
VNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHA
Sbjct: 61 VNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHA 120
Query: 121 PPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE 180
PPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE
Sbjct: 121 PPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE 180
Query: 181 ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN 240
ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN
Sbjct: 181 ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN 240
Query: 241 PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD 300
PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD
Sbjct: 241 PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD 300
Query: 301 LSKYDVQVRAAVSSMCREAGLWSEWSQPIYVG 332
LSKYDVQVRAAVSSMCREAGLWSEWSQPIYVG
Sbjct: 301 LSKYDVQVRAAVSSMCREAGLWSEWSQPIYVG 332
>gi|28559029 interleukin 5 receptor, alpha isoform 2 precursor [Homo
sapiens]
Length = 333
Score = 681 bits (1756), Expect = 0.0
Identities = 332/332 (100%), Positives = 332/332 (100%)
Query: 1 MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRN 60
MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRN
Sbjct: 1 MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRN 60
Query: 61 VNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHA 120
VNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHA
Sbjct: 61 VNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHA 120
Query: 121 PPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE 180
PPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE
Sbjct: 121 PPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE 180
Query: 181 ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN 240
ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN
Sbjct: 181 ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN 240
Query: 241 PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD 300
PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD
Sbjct: 241 PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD 300
Query: 301 LSKYDVQVRAAVSSMCREAGLWSEWSQPIYVG 332
LSKYDVQVRAAVSSMCREAGLWSEWSQPIYVG
Sbjct: 301 LSKYDVQVRAAVSSMCREAGLWSEWSQPIYVG 332
>gi|10834992 interleukin 13 receptor, alpha 2 precursor [Homo
sapiens]
Length = 380
Score = 111 bits (278), Expect = 1e-24
Identities = 96/351 (27%), Positives = 160/351 (45%), Gaps = 33/351 (9%)
Query: 25 DEKISLLPPVNFTIKVTG-LAQVLLQWKPNPDQEQ-RNVNLEYQVKINAPKEDDYETRIT 82
D +I + PP +F I G L + LQW+P + + +EY++K + ++T IT
Sbjct: 27 DTEIKVNPPQDFEIVDPGYLGYLYLQWQPPLSLDHFKECTVEYELKYRNIGSETWKTIIT 86
Query: 83 ES---KCVTILHKGFSASVRTILQ---NDHSLLASSWASAELH-APPGSPGTSIVNLTCT 135
++ K L+KG A + T+L + S + SSWA +P G P T + ++ C
Sbjct: 87 KNLHYKDGFDLNKGIEAKIHTLLPWQCTNGSEVQSSWAETTYWISPQGIPETKVQDMDCV 146
Query: 136 TNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE--ECQEYSKDTLGRN 193
+ L C+W G DT Y L+Y Y +C +Y K G+N
Sbjct: 147 YYNWQ-----------YLLCSWKPGIGVLLDTNYNLFYWYEGLDHALQCVDYIKAD-GQN 194
Query: 194 IACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGT- 252
I C FP ++ + + VNGSS++ IR F L I + PP+ +T E +
Sbjct: 195 IGCRFP--YLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLPPVYLTFTRESSC 252
Query: 253 RLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDDLSKYDVQVRAAV 312
+ ++W P+ P CFDYE++I + + ++ + VR+ V
Sbjct: 253 EIKLKWSIPLGPIPARCFDYEIEIREDDTTLVTATVENETYTLKTTNETRQLCFVVRSKV 312
Query: 313 SSMCREAGLWSEWS-QPIYVGNDEHKP--LREW----FVIVIMATICFILL 356
+ C + G+WSEWS + + G D K LR W F+++++ + +LL
Sbjct: 313 NIYCSDDGIWSEWSDKQCWEGEDLSKKTLLRFWLPFGFILILVIFVTGLLL 363
>gi|4504647 interleukin 13 receptor, alpha 1 precursor [Homo
sapiens]
Length = 427
Score = 100 bits (249), Expect = 2e-21
Identities = 97/404 (24%), Positives = 163/404 (40%), Gaps = 49/404 (12%)
Query: 32 PPV-NFTIKVTGLAQVLLQWKPNPDQEQRNVNLEYQVKINAPKEDDYETRITESKCVTIL 90
PPV N ++ V L V+ W P P+ N +L Y K+D T L
Sbjct: 33 PPVTNLSVSVENLCTVIWTWNP-PEGASSNCSLWYFSHFG-DKQDKKIAPETRRSIEVPL 90
Query: 91 HKGFSASVRTILQNDHSLLASSWASAELHAPPGSPGTSIVNLTCTTNTTEDNYSRLRSYQ 150
++ V + + S S + P G P +++ L C + SY
Sbjct: 91 NERICLQVGSQCSTNESEKPSILVEKCISPPEGDPESAVTELQCIWHNL--------SY- 141
Query: 151 VSLHCTWLVGTDAPEDTQYFLYYRYGSWTE--ECQEYSKDTLGRNIACWFPRTFILSKGR 208
+ C+WL G + DT Y LYY + S + +C+ ++ G+ C F T +
Sbjct: 142 --MKCSWLPGRNTSPDTNYTLYYWHRSLEKIHQCENIFRE--GQYFGCSFDLTKVKDSSF 197
Query: 209 DWLAVLVNGSSKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGTRLSIQWEKPVSAFPIH 268
+ +V + I+P + L + + +PP L +QWE P + F
Sbjct: 198 EQHSVQIMVKDNAGKIKPSFNIVPLTSRVKPDPPHIKNLSFHNDDLYVQWENPQN-FISR 256
Query: 269 CFDYEVKIHNTRNG-----YLQIEKLMTNAFISIIDDLSKY-----------DVQVRAAV 312
C YEV+++N++ Y+Q K F +++ S + V++R
Sbjct: 257 CLFYEVEVNNSQTETHNVFYVQEAKCENPEFERNVENTSCFMVPGVLPDTLNTVRIRVKT 316
Query: 313 SSMCREAG-LWSEWSQPIYVGNDEHKPLREWFVIVIMATICFILLILSLICKICHLWIKL 371
+ +C E LWS WSQ + +G + L ++++ + +++L L K L I +
Sbjct: 317 NKLCYEDDKLWSNWSQEMSIGKKRNSTLYITMLLIVPVIVAGAIIVLLLYLK--RLKIII 374
Query: 372 FPPIPAPKSNIKDLFVTTN-----------YEKAGSSETEIEVI 404
FPPIP P K++F N YEK ET+ V+
Sbjct: 375 FPPIPDPGKIFKEMFGDQNDDTLHWKKYDIYEKQTKEETDSVVL 418
>gi|20070195 colony stimulating factor 2 receptor alpha chain
isoform a precursor [Homo sapiens]
Length = 400
Score = 97.1 bits (240), Expect = 3e-20
Identities = 92/362 (25%), Positives = 151/362 (41%), Gaps = 68/362 (18%)
Query: 57 EQRNVNLEYQVKINAP---------KEDDYETRITESKCVTI-----LHKG--FSASVRT 100
+ R +NL + + N K E R++ ++C LH+G F V T
Sbjct: 41 DSRTMNLSWDCQENTTFSKCFLTDKKNRVVEPRLSNNECSCTFREICLHEGVTFEVHVNT 100
Query: 101 ILQNDHSLLASSWASAELHAPPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVG 160
+ L L+ G GT+ N +C + ++CTW G
Sbjct: 101 SQRGFQQKL--------LYPNSGREGTAAQNFSCFIYNAD-----------LMNCTWARG 141
Query: 161 TDAPEDTQYFLYYRYGSWTEE--CQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGS 218
AP D QYFLY R E C Y +D+ G ++ C L+ R++ LVNG+
Sbjct: 142 PTAPRDVQYFLYIRNSKRRREIRCPYYIQDS-GTHVGCHLDNLSGLTS-RNYF--LVNGT 197
Query: 219 SKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGTRLSIQWEKPVSAFPIHC--FDYEVKI 276
S+ I+ FD L I++ NPP NVT T ++W++P + + F Y++ +
Sbjct: 198 SREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQYQLDV 257
Query: 277 H--NTRNGYLQIEKLMTNAFISIIDDL------------SKYDVQVRAAVSSMCREAGLW 322
H NT+ G N I++ DL +K+ V++RAA + W
Sbjct: 258 HRKNTQPG-------TENLLINVSGDLENRYNFPSSEPRAKHSVKIRAADVRILN----W 306
Query: 323 SEWSQPIYVGNDEHKPLREWFVIVIMATICFILLILSLICKICHLWIKLFPPIPAPKSNI 382
S WS+ I G+D+ + ++++ ++L + K +LFPP+P K +
Sbjct: 307 SSWSEAIEFGSDDGNLGSVYIYVLLIVGTLVCGIVLGFLFKRFLRIQRLFPPVPQIKDKL 366
Query: 383 KD 384
D
Sbjct: 367 ND 368
>gi|238908519 colony stimulating factor 2 receptor alpha chain
isoform g precursor [Homo sapiens]
Length = 410
Score = 97.1 bits (240), Expect = 3e-20
Identities = 92/362 (25%), Positives = 151/362 (41%), Gaps = 68/362 (18%)
Query: 57 EQRNVNLEYQVKINAP---------KEDDYETRITESKCVTI-----LHKG--FSASVRT 100
+ R +NL + + N K E R++ ++C LH+G F V T
Sbjct: 41 DSRTMNLSWDCQENTTFSKCFLTDKKNRVVEPRLSNNECSCTFREICLHEGVTFEVHVNT 100
Query: 101 ILQNDHSLLASSWASAELHAPPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVG 160
+ L L+ G GT+ N +C + ++CTW G
Sbjct: 101 SQRGFQQKL--------LYPNSGREGTAAQNFSCFIYNAD-----------LMNCTWARG 141
Query: 161 TDAPEDTQYFLYYRYGSWTEE--CQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGS 218
AP D QYFLY R E C Y +D+ G ++ C L+ R++ LVNG+
Sbjct: 142 PTAPRDVQYFLYIRNSKRRREIRCPYYIQDS-GTHVGCHLDNLSGLTS-RNYF--LVNGT 197
Query: 219 SKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGTRLSIQWEKPVSAFPIHC--FDYEVKI 276
S+ I+ FD L I++ NPP NVT T ++W++P + + F Y++ +
Sbjct: 198 SREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQYQLDV 257
Query: 277 H--NTRNGYLQIEKLMTNAFISIIDDL------------SKYDVQVRAAVSSMCREAGLW 322
H NT+ G N I++ DL +K+ V++RAA + W
Sbjct: 258 HRKNTQPG-------TENLLINVSGDLENRYNFPSSEPRAKHSVKIRAADVRILN----W 306
Query: 323 SEWSQPIYVGNDEHKPLREWFVIVIMATICFILLILSLICKICHLWIKLFPPIPAPKSNI 382
S WS+ I G+D+ + ++++ ++L + K +LFPP+P K +
Sbjct: 307 SSWSEAIEFGSDDGNLGSVYIYVLLIVGTLVCGIVLGFLFKRFLRIQRLFPPVPQIKDKL 366
Query: 383 KD 384
D
Sbjct: 367 ND 368
>gi|238908515 colony stimulating factor 2 receptor alpha chain
isoform a precursor [Homo sapiens]
Length = 400
Score = 97.1 bits (240), Expect = 3e-20
Identities = 92/362 (25%), Positives = 151/362 (41%), Gaps = 68/362 (18%)
Query: 57 EQRNVNLEYQVKINAP---------KEDDYETRITESKCVTI-----LHKG--FSASVRT 100
+ R +NL + + N K E R++ ++C LH+G F V T
Sbjct: 41 DSRTMNLSWDCQENTTFSKCFLTDKKNRVVEPRLSNNECSCTFREICLHEGVTFEVHVNT 100
Query: 101 ILQNDHSLLASSWASAELHAPPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVG 160
+ L L+ G GT+ N +C + ++CTW G
Sbjct: 101 SQRGFQQKL--------LYPNSGREGTAAQNFSCFIYNAD-----------LMNCTWARG 141
Query: 161 TDAPEDTQYFLYYRYGSWTEE--CQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGS 218
AP D QYFLY R E C Y +D+ G ++ C L+ R++ LVNG+
Sbjct: 142 PTAPRDVQYFLYIRNSKRRREIRCPYYIQDS-GTHVGCHLDNLSGLTS-RNYF--LVNGT 197
Query: 219 SKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGTRLSIQWEKPVSAFPIHC--FDYEVKI 276
S+ I+ FD L I++ NPP NVT T ++W++P + + F Y++ +
Sbjct: 198 SREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQYQLDV 257
Query: 277 H--NTRNGYLQIEKLMTNAFISIIDDL------------SKYDVQVRAAVSSMCREAGLW 322
H NT+ G N I++ DL +K+ V++RAA + W
Sbjct: 258 HRKNTQPG-------TENLLINVSGDLENRYNFPSSEPRAKHSVKIRAADVRILN----W 306
Query: 323 SEWSQPIYVGNDEHKPLREWFVIVIMATICFILLILSLICKICHLWIKLFPPIPAPKSNI 382
S WS+ I G+D+ + ++++ ++L + K +LFPP+P K +
Sbjct: 307 SSWSEAIEFGSDDGNLGSVYIYVLLIVGTLVCGIVLGFLFKRFLRIQRLFPPVPQIKDKL 366
Query: 383 KD 384
D
Sbjct: 367 ND 368
>gi|27437032 colony stimulating factor 2 receptor alpha chain
isoform a precursor [Homo sapiens]
Length = 400
Score = 97.1 bits (240), Expect = 3e-20
Identities = 92/362 (25%), Positives = 151/362 (41%), Gaps = 68/362 (18%)
Query: 57 EQRNVNLEYQVKINAP---------KEDDYETRITESKCVTI-----LHKG--FSASVRT 100
+ R +NL + + N K E R++ ++C LH+G F V T
Sbjct: 41 DSRTMNLSWDCQENTTFSKCFLTDKKNRVVEPRLSNNECSCTFREICLHEGVTFEVHVNT 100
Query: 101 ILQNDHSLLASSWASAELHAPPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVG 160
+ L L+ G GT+ N +C + ++CTW G
Sbjct: 101 SQRGFQQKL--------LYPNSGREGTAAQNFSCFIYNAD-----------LMNCTWARG 141
Query: 161 TDAPEDTQYFLYYRYGSWTEE--CQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGS 218
AP D QYFLY R E C Y +D+ G ++ C L+ R++ LVNG+
Sbjct: 142 PTAPRDVQYFLYIRNSKRRREIRCPYYIQDS-GTHVGCHLDNLSGLTS-RNYF--LVNGT 197
Query: 219 SKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGTRLSIQWEKPVSAFPIHC--FDYEVKI 276
S+ I+ FD L I++ NPP NVT T ++W++P + + F Y++ +
Sbjct: 198 SREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQYQLDV 257
Query: 277 H--NTRNGYLQIEKLMTNAFISIIDDL------------SKYDVQVRAAVSSMCREAGLW 322
H NT+ G N I++ DL +K+ V++RAA + W
Sbjct: 258 HRKNTQPG-------TENLLINVSGDLENRYNFPSSEPRAKHSVKIRAADVRILN----W 306
Query: 323 SEWSQPIYVGNDEHKPLREWFVIVIMATICFILLILSLICKICHLWIKLFPPIPAPKSNI 382
S WS+ I G+D+ + ++++ ++L + K +LFPP+P K +
Sbjct: 307 SSWSEAIEFGSDDGNLGSVYIYVLLIVGTLVCGIVLGFLFKRFLRIQRLFPPVPQIKDKL 366
Query: 383 KD 384
D
Sbjct: 367 ND 368
>gi|238908521 colony stimulating factor 2 receptor alpha chain
isoform h [Homo sapiens]
Length = 267
Score = 95.1 bits (235), Expect = 1e-19
Identities = 71/250 (28%), Positives = 116/250 (46%), Gaps = 33/250 (13%)
Query: 153 LHCTWLVGTDAPEDTQYFLYYRYGSWTEE--CQEYSKDTLGRNIACWFPRTFILSKGRDW 210
++CTW G AP D QYFLY R E C Y +D+ G ++ C L+ R++
Sbjct: 1 MNCTWARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQDS-GTHVGCHLDNLSGLTS-RNY 58
Query: 211 LAVLVNGSSKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGTRLSIQWEKPVSAFPIHC- 269
LVNG+S+ I+ FD L I++ NPP NVT T ++W++P + +
Sbjct: 59 F--LVNGTSREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYL 116
Query: 270 -FDYEVKIH--NTRNGYLQIEKLMTNAFISIIDDL------------SKYDVQVRAAVSS 314
F Y++ +H NT+ G N I++ DL +K+ V++RAA
Sbjct: 117 DFQYQLDVHRKNTQPG-------TENLLINVSGDLENRYNFPSSEPRAKHSVKIRAADVR 169
Query: 315 MCREAGLWSEWSQPIYVGNDEHKPLREWFVIVIMATICFILLILSLICKICHLWIKLFPP 374
+ WS WS+ I G+D+ + ++++ ++L + K +LFPP
Sbjct: 170 ILN----WSSWSEAIEFGSDDGNLGSVYIYVLLIVGTLVCGIVLGFLFKRFLRIQRLFPP 225
Query: 375 IPAPKSNIKD 384
+P K + D
Sbjct: 226 VPQIKDKLND 235
>gi|238908517 colony stimulating factor 2 receptor alpha chain
isoform f precursor [Homo sapiens]
Length = 434
Score = 82.8 bits (203), Expect = 5e-16
Identities = 82/311 (26%), Positives = 129/311 (41%), Gaps = 68/311 (21%)
Query: 57 EQRNVNLEYQVKINAP---------KEDDYETRITESKCVTI-----LHKG--FSASVRT 100
+ R +NL + + N K E R++ ++C LH+G F V T
Sbjct: 41 DSRTMNLSWDCQENTTFSKCFLTDKKNRVVEPRLSNNECSCTFREICLHEGVTFEVHVNT 100
Query: 101 ILQNDHSLLASSWASAELHAPPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVG 160
+ L L+ G GT+ N +C + ++CTW G
Sbjct: 101 SQRGFQQKL--------LYPNSGREGTAAQNFSCFIYNAD-----------LMNCTWARG 141
Query: 161 TDAPEDTQYFLYYRYGSWTEE--CQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGS 218
AP D QYFLY R E C Y +D+ G ++ C L+ R++ LVNG+
Sbjct: 142 PTAPRDVQYFLYIRNSKRRREIRCPYYIQDS-GTHVGCHLDNLSGLTS-RNYF--LVNGT 197
Query: 219 SKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGTRLSIQWEKPVSAFPIHC--FDYEVKI 276
S+ I+ FD L I++ NPP NVT T ++W++P + + F Y++ +
Sbjct: 198 SREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQYQLDV 257
Query: 277 H--NTRNGYLQIEKLMTNAFISIIDDL------------SKYDVQVRAAVSSMCREAGLW 322
H NT+ G N I++ DL +K+ V++RAA + W
Sbjct: 258 HRKNTQPG-------TENLLINVSGDLENRYNFPSSEPRAKHSVKIRAADVRILN----W 306
Query: 323 SEWSQPIYVGN 333
S WS+ I G+
Sbjct: 307 SSWSEAIEFGS 317
>gi|27437036 colony stimulating factor 2 receptor alpha chain
isoform c precursor [Homo sapiens]
Length = 333
Score = 82.8 bits (203), Expect = 5e-16
Identities = 82/311 (26%), Positives = 129/311 (41%), Gaps = 68/311 (21%)
Query: 57 EQRNVNLEYQVKINAP---------KEDDYETRITESKCVTI-----LHKG--FSASVRT 100
+ R +NL + + N K E R++ ++C LH+G F V T
Sbjct: 41 DSRTMNLSWDCQENTTFSKCFLTDKKNRVVEPRLSNNECSCTFREICLHEGVTFEVHVNT 100
Query: 101 ILQNDHSLLASSWASAELHAPPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVG 160
+ L L+ G GT+ N +C + ++CTW G
Sbjct: 101 SQRGFQQKL--------LYPNSGREGTAAQNFSCFIYNAD-----------LMNCTWARG 141
Query: 161 TDAPEDTQYFLYYRYGSWTEE--CQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGS 218
AP D QYFLY R E C Y +D+ G ++ C L+ R++ LVNG+
Sbjct: 142 PTAPRDVQYFLYIRNSKRRREIRCPYYIQDS-GTHVGCHLDNLSGLTS-RNYF--LVNGT 197
Query: 219 SKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGTRLSIQWEKPVSAFPIHC--FDYEVKI 276
S+ I+ FD L I++ NPP NVT T ++W++P + + F Y++ +
Sbjct: 198 SREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQYQLDV 257
Query: 277 H--NTRNGYLQIEKLMTNAFISIIDDL------------SKYDVQVRAAVSSMCREAGLW 322
H NT+ G N I++ DL +K+ V++RAA + W
Sbjct: 258 HRKNTQPG-------TENLLINVSGDLENRYNFPSSEPRAKHSVKIRAADVRILN----W 306
Query: 323 SEWSQPIYVGN 333
S WS+ I G+
Sbjct: 307 SSWSEAIEFGS 317
>gi|13324710 interleukin 3 receptor, alpha precursor [Homo sapiens]
Length = 378
Score = 81.6 bits (200), Expect = 1e-15
Identities = 85/295 (28%), Positives = 120/295 (40%), Gaps = 33/295 (11%)
Query: 123 GSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE-- 180
G P NLTC + + L C+W VG AP D QY LY + +
Sbjct: 101 GKPWAGAENLTCWIHDVD-----------FLSCSWAVGPGAPADVQYDLYLNVANRRQQY 149
Query: 181 ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN 240
EC Y D G I C F LS G +LV G S I D+ I+ +
Sbjct: 150 ECLHYKTDAQGTRIGCRFDDISRLSSGSQSSHILVRGRSAAFGIPCTDKFVVFSQIEILT 209
Query: 241 PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD 300
PP N+TA+ T + W K S F F YE++I + E++ +++
Sbjct: 210 PP-NMTAKCNKTHSFMHW-KMRSHFN-RKFRYELQIQKRMQPVI-TEQVRDRTSFQLLNP 265
Query: 301 LSKYDVQVRAAVSSMCREAGLWSEWSQP--IYVGNDEHKPLREWFVIVIMATICFILLI- 357
Y VQ+RA R S WS P +E R W +++A + L+
Sbjct: 266 -GTYTVQIRARE----RVYEFLSAWSTPQRFECDQEEGANTRAWRTSLLIALGTLLALVC 320
Query: 358 LSLICKICHLWIKLFPPIPAPKSNIKDLF-----VTTNYEKAGSSE---TEIEVI 404
+ +IC+ + +LFP IP K I D F V KAG E TE++V+
Sbjct: 321 VFVICRRYLVMQRLFPRIPHMKDPIGDSFQNDKLVVWEAGKAGLEECLVTEVQVV 375
>gi|27437034 colony stimulating factor 2 receptor alpha chain
isoform b precursor [Homo sapiens]
Length = 377
Score = 81.3 bits (199), Expect = 2e-15
Identities = 81/307 (26%), Positives = 127/307 (41%), Gaps = 68/307 (22%)
Query: 57 EQRNVNLEYQVKINAP---------KEDDYETRITESKCVTI-----LHKG--FSASVRT 100
+ R +NL + + N K E R++ ++C LH+G F V T
Sbjct: 41 DSRTMNLSWDCQENTTFSKCFLTDKKNRVVEPRLSNNECSCTFREICLHEGVTFEVHVNT 100
Query: 101 ILQNDHSLLASSWASAELHAPPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVG 160
+ L L+ G GT+ N +C + ++CTW G
Sbjct: 101 SQRGFQQKL--------LYPNSGREGTAAQNFSCFIYNAD-----------LMNCTWARG 141
Query: 161 TDAPEDTQYFLYYRYGSWTEE--CQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGS 218
AP D QYFLY R E C Y +D+ G ++ C L+ R++ LVNG+
Sbjct: 142 PTAPRDVQYFLYIRNSKRRREIRCPYYIQDS-GTHVGCHLDNLSGLTS-RNYF--LVNGT 197
Query: 219 SKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGTRLSIQWEKPVSAFPIHC--FDYEVKI 276
S+ I+ FD L I++ NPP NVT T ++W++P + + F Y++ +
Sbjct: 198 SREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQYQLDV 257
Query: 277 H--NTRNGYLQIEKLMTNAFISIIDDL------------SKYDVQVRAAVSSMCREAGLW 322
H NT+ G N I++ DL +K+ V++RAA + W
Sbjct: 258 HRKNTQPG-------TENLLINVSGDLENRYNFPSSEPRAKHSVKIRAADVRILN----W 306
Query: 323 SEWSQPI 329
S WS+ I
Sbjct: 307 SSWSEAI 313
>gi|4506107 prolactin receptor [Homo sapiens]
Length = 622
Score = 54.7 bits (130), Expect = 2e-07
Identities = 56/241 (23%), Positives = 104/241 (43%), Gaps = 27/241 (11%)
Query: 155 CTWLVGTDAPEDTQYFL-YYRYG-SWTEECQEYSKDTLGRNIACWFPRTFILSKGRDWLA 212
C W GTD T Y L Y+R G + EC +Y T G N +C F + + S R ++
Sbjct: 46 CWWRPGTDGGLPTNYSLTYHREGETLMHECPDYI--TGGPN-SCHFGKQYT-SMWRTYI- 100
Query: 213 VLVNGSSKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGTR-----LSIQWEKPV----- 262
++VN +++ + + + I Q +PPL + E++ L I+W P
Sbjct: 101 MMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLK 160
Query: 263 SAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDDLSKYDVQVRAAVSSMCR-EAGL 321
+ + ++ +K + T I + KY VQVR C+ + G
Sbjct: 161 TGWFTLLYEIRLKPEKAAEWEIHFAGQQTEFKILSLHPGQKYLVQVR------CKPDHGY 214
Query: 322 WSEWSQPIYVGNDEHKPLRE---WFVIVIMATICFILLILSLICKICHLWIKLFPPIPAP 378
WS WS ++ + + W + +++ + ++++ ++ K + +FPP+P P
Sbjct: 215 WSAWSPATFIQIPSDFTMNDTTVWISVAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGP 274
Query: 379 K 379
K
Sbjct: 275 K 275
>gi|4557882 interleukin 2 receptor, gamma precursor [Homo sapiens]
Length = 369
Score = 52.4 bits (124), Expect = 8e-07
Identities = 57/241 (23%), Positives = 107/241 (44%), Gaps = 19/241 (7%)
Query: 153 LHCTWLVGTDAPEDTQYFLYYRY-GSWTEECQEYSKDTLGRNIA--CWFPRTFILSKGRD 209
++CTW ++ P+ T L+Y Y S ++ Q+ S I C + I
Sbjct: 70 MNCTWNSSSE-PQPTNLTLHYWYKNSDNDKVQKCSHYLFSEEITSGCQLQKKEI----HL 124
Query: 210 WLAVLVNGSSKHSAIRPFDQLFALHAIDQINPPLNVTA-EIEGTRLSIQWEKPVSAFPIH 268
+ +V R Q+ L + P N+T ++ ++L + W + F H
Sbjct: 125 YQTFVVQLQDPREPRRQATQMLKLQNLVIPWAPENLTLHKLSESQLELNWN---NRFLNH 181
Query: 269 CFDYEVKIHNTRNGYLQIEKLMTNAFISI--IDDLSKYDVQVRAAVSSMCREAGLWSEWS 326
C ++ V+ + + + S+ +D +Y +VR+ + +C A WSEWS
Sbjct: 182 CLEHLVQYRTDWDHSWTEQSVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEWS 241
Query: 327 QPIYVGNDEHKPLREWFVI-VIMATICFILLILSLICKICHLWI-KLFPPIPAPKSNIKD 384
PI+ G++ K F + ++ ++ + LI+SL+C + W+ + P IP K N++D
Sbjct: 242 HPIHWGSNTSKENPFLFALEAVVISVGSMGLIISLLC--VYFWLERTMPRIPTLK-NLED 298
Query: 385 L 385
L
Sbjct: 299 L 299
>gi|27437040 colony stimulating factor 2 receptor alpha chain
isoform e precursor [Homo sapiens]
Length = 233
Score = 48.5 bits (114), Expect = 1e-05
Identities = 51/192 (26%), Positives = 77/192 (40%), Gaps = 41/192 (21%)
Query: 57 EQRNVNLEYQVKINAP---------KEDDYETRITESKCVTI-----LHKG--FSASVRT 100
+ R +NL + + N K E R++ ++C LH+G F V T
Sbjct: 41 DSRTMNLSWDCQENTTFSKCFLTDKKNRVVEPRLSNNECSCTFREICLHEGVTFEVHVNT 100
Query: 101 ILQNDHSLLASSWASAELHAPPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVG 160
+ L L+ G GT+ N +C + ++CTW G
Sbjct: 101 SQRGFQQKL--------LYPNSGREGTAAQNFSCFIYNAD-----------LMNCTWARG 141
Query: 161 TDAPEDTQYFLYYRYGSWTEE--CQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGS 218
AP D QYFLY R E C Y +D+ G ++ C L+ R++ LVNG+
Sbjct: 142 PTAPRDVQYFLYIRNSKRRREIRCPYYIQDS-GTHVGCHLDNLSGLT-SRNYF--LVNGT 197
Query: 219 SKHSAIRPFDQL 230
S+ I+ FD L
Sbjct: 198 SREIGIQFFDSL 209
>gi|4503591 erythropoietin receptor precursor [Homo sapiens]
Length = 508
Score = 47.4 bits (111), Expect = 2e-05
Identities = 37/169 (21%), Positives = 78/169 (46%), Gaps = 9/169 (5%)
Query: 227 FDQLFALHAIDQINPPLNVTAEI--EGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYL 284
+ ++ ++ + ++ P+ + A + E + ++W P YEV + + NG
Sbjct: 133 YHRVIHINEVVLLDAPVGLVARLADESGHVVLRWLPPPETPMTSHIRYEVDV-SAGNGAG 191
Query: 285 QIEKL-----MTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGNDEHKPL 339
++++ T +S + ++Y VRA ++ G WS WS+P+ +
Sbjct: 192 SVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSF-GGFWSAWSEPVSLLTPSDLDP 250
Query: 340 REWFVIVIMATICFILLILSLICKICHLWIKLFPPIPAPKSNIKDLFVT 388
+ +I+ I +L +L+L+ L K++P IP+P+S + LF T
Sbjct: 251 LILTLSLILVVILVLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTT 299
>gi|4503993 growth hormone receptor precursor [Homo sapiens]
Length = 638
Score = 44.3 bits (103), Expect = 2e-04
Identities = 58/271 (21%), Positives = 111/271 (40%), Gaps = 36/271 (13%)
Query: 135 TTNTTEDNYSRLRSYQ-VSLHCTWLV----GTDAPEDTQYFLYYRYGS-WTEECQEYSKD 188
T ++ E +++ RS + + C W GT Q F R WT+E +E
Sbjct: 45 TNSSKEPKFTKCRSPERETFSCHWTDEVHHGTKNLGPIQLFYTRRNTQEWTQEWKECPDY 104
Query: 189 TLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQINPP------ 242
+C+F +F W+ + +S + ++ F++ I Q +PP
Sbjct: 105 VSAGENSCYFNSSFTSI----WIPYCIKLTSNGGTVD--EKCFSVDEIVQPDPPIALNWT 158
Query: 243 -LNVTAEIEGTRLSIQWEKPVSA-----FPIHCFDYEVKIHNTRNGYLQIEKLMTNAFIS 296
LNV+ + ++WE P +A + + ++ + K N + L T+ +
Sbjct: 159 LLNVSLTGIHADIQVRWEAPRNADIQKGWMVLEYELQYKEVNETKWKMMDPILTTSVPVY 218
Query: 297 IIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGNDEHKPLR-------EWFVIVIMA 349
+ +Y+V+VR S R +G + E+S+ +YV + W +I+I
Sbjct: 219 SLKVDKEYEVRVR----SKQRNSGNYGEFSEVLYVTLPQMSQFTCEEDFYFPWLLIIIFG 274
Query: 350 TICF-ILLILSLICKICHLWIKLFPPIPAPK 379
++L + L K + + + PP+P PK
Sbjct: 275 IFGLTVMLFVFLFSKQQRIKMLILPPVPVPK 305
>gi|31083174 interleukin 21 receptor precursor [Homo sapiens]
Length = 538
Score = 42.4 bits (98), Expect = 8e-04
Identities = 39/162 (24%), Positives = 63/162 (38%), Gaps = 18/162 (11%)
Query: 241 PPLNVTAEIEGTRLSIQW----EKPVSAFPIHCFDYEVKIHNT--------RNGYLQIEK 288
PP NVT G + +I W E P YE++ N R + ++
Sbjct: 122 PPFNVTVTFSG-QYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS 180
Query: 289 LMTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGNDEHKPLREW---FVI 345
+ S Y++QVRA G WSEWS P+ + W ++
Sbjct: 181 RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLL 240
Query: 346 VIMATICFILLILSL-ICKICHLWIKLFPPIPAPKSNIKDLF 386
+++ I FI SL + LW K++ +P+P+ L+
Sbjct: 241 LLLLVIVFIPAFWSLKTHPLWRLWKKIW-AVPSPERFFMPLY 281
>gi|11141869 interleukin 21 receptor precursor [Homo sapiens]
Length = 538
Score = 42.4 bits (98), Expect = 8e-04
Identities = 39/162 (24%), Positives = 63/162 (38%), Gaps = 18/162 (11%)
Query: 241 PPLNVTAEIEGTRLSIQW----EKPVSAFPIHCFDYEVKIHNT--------RNGYLQIEK 288
PP NVT G + +I W E P YE++ N R + ++
Sbjct: 122 PPFNVTVTFSG-QYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS 180
Query: 289 LMTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGNDEHKPLREW---FVI 345
+ S Y++QVRA G WSEWS P+ + W ++
Sbjct: 181 RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLL 240
Query: 346 VIMATICFILLILSL-ICKICHLWIKLFPPIPAPKSNIKDLF 386
+++ I FI SL + LW K++ +P+P+ L+
Sbjct: 241 LLLLVIVFIPAFWSLKTHPLWRLWKKIW-AVPSPERFFMPLY 281
>gi|31083180 interleukin 21 receptor precursor [Homo sapiens]
Length = 538
Score = 42.4 bits (98), Expect = 8e-04
Identities = 39/162 (24%), Positives = 63/162 (38%), Gaps = 18/162 (11%)
Query: 241 PPLNVTAEIEGTRLSIQW----EKPVSAFPIHCFDYEVKIHNT--------RNGYLQIEK 288
PP NVT G + +I W E P YE++ N R + ++
Sbjct: 122 PPFNVTVTFSG-QYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS 180
Query: 289 LMTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGNDEHKPLREW---FVI 345
+ S Y++QVRA G WSEWS P+ + W ++
Sbjct: 181 RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLL 240
Query: 346 VIMATICFILLILSL-ICKICHLWIKLFPPIPAPKSNIKDLF 386
+++ I FI SL + LW K++ +P+P+ L+
Sbjct: 241 LLLLVIVFIPAFWSLKTHPLWRLWKKIW-AVPSPERFFMPLY 281
>gi|4559408 colony stimulating factor 2 receptor, beta precursor
[Homo sapiens]
Length = 897
Score = 40.4 bits (93), Expect = 0.003
Identities = 48/214 (22%), Positives = 86/214 (40%), Gaps = 20/214 (9%)
Query: 153 LHCTWLVGTDAPEDTQYFLYYRYG--SWTEECQEYSKDTLGR---NIACWFPRTFILSKG 207
L C+W V + + L+Y+ + EEC ++ LG C P + G
Sbjct: 258 LSCSWEVRKEVASSVSFGLFYKPSPDAGEEECSPVLREGLGSLHTRHHCQIPVPDPATHG 317
Query: 208 RDWLAVLVNGSSKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGTRLSIQWEKPVSAFPI 267
+ ++V + KH + + I P LNVT + G S++WE +
Sbjct: 318 QYIVSVQPRRAEKH--------IKSSVNIQMAPPSLNVTKD--GDSYSLRWETMKMRYEH 367
Query: 268 --HCFDYEVKIHNTRNGYLQIEKLMTNAFISI--IDDLSKYDVQVRAAVSSMCREAGLWS 323
H F+ + + + E L +++ ++ ++Y +VR S G+WS
Sbjct: 368 IDHTFEIQYRKDTATWKDSKTETLQNAHSMALPALEPSTRYWARVRVRTSRTGYN-GIWS 426
Query: 324 EWSQPIYVGNDEHKPLREWFVIVIMATICFILLI 357
EWS+ + P+ +IVI TI +L +
Sbjct: 427 EWSEARSWDTESVLPMWVLALIVIFLTIAVLLAL 460
>gi|4885491 myeloproliferative leukemia virus oncogene precursor
[Homo sapiens]
Length = 635
Score = 39.7 bits (91), Expect = 0.005
Identities = 65/300 (21%), Positives = 107/300 (35%), Gaps = 40/300 (13%)
Query: 44 AQVLLQWKPNPDQEQRNVNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQ 103
AQ + W+ P Q + +E T S ++ L G S ++ +
Sbjct: 212 AQPTMPWQDGPKQTSPS------------REASALTAEGGSCLISGLQPGNSYWLQLRSE 259
Query: 104 NDHSLLASSWASAELHAPPGSPGTSI-VNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTD 162
D L SW S L PG ++ + L C T ++ + C W
Sbjct: 260 PDGISLGGSWGSWSLPVTVDLPGDAVALGLQCFTLDLKN-----------VTCQWQQQDH 308
Query: 163 APEDTQYFLYY---------RYGSWTEECQEYSKDTLGRNIACWFPRTFILSKGRDWLAV 213
A +Q F Y+ RY W E C+E K G F R S+ + +
Sbjct: 309 A--SSQGFFYHSRARCCPRDRYPIW-ENCEEEEKTNPGLQTP-QFSRCHFKSRNDSIIHI 364
Query: 214 LVNGSSKHSAIRPF-DQLFALHAIDQINPPLNVTAEIEGTRLSIQWEKPVS-AFPIHCFD 271
LV ++ + + F +H ++ P EI L ++W+ P S A C+
Sbjct: 365 LVEVTTAPGTVHSYLGSPFWIHQAVRLPTPNLHWREISSGHLELEWQHPSSWAAQETCYQ 424
Query: 272 YEVKIHNTRNGYLQIEKLMTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIYV 331
++ + L + S+Y +Q+RA ++ + G WS WS P V
Sbjct: 425 LRYTGEGHQDWKVLEPPLGARGGTLELRPRSRYRLQLRARLNGPTYQ-GPWSSWSDPTRV 483
>gi|4758062 cytokine receptor-like factor 1 [Homo sapiens]
Length = 422
Score = 39.7 bits (91), Expect = 0.005
Identities = 61/248 (24%), Positives = 98/248 (39%), Gaps = 58/248 (23%)
Query: 105 DHSLLASSWASAELHAPPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAP 164
D S+LA S L PP P VN++C + +D L C W G
Sbjct: 120 DGSILAGSCLYVGL--PPEKP----VNISCWSKNMKD-----------LTCRWTPGAHGE 162
Query: 165 E--DTQYFLYYRYGSWTEE--CQEYSKDTLGRNIACWFPRTFILSKGRD-WLAVLVNGSS 219
T Y L Y+ + ++ C+EY T+G + +C P+ L + W+ S
Sbjct: 163 TFLHTNYSLKYKLRWYGQDNTCEEYH--TVGPH-SCHIPKDLALFTPYEIWVEATNRLGS 219
Query: 220 KHSAIRPFDQLFALHAIDQINPPLNVTAEIEG---TRLSIQWEKPVSAFPIHCFDYEVKI 276
S + D L + +PP +V G +LS++W P + + F ++ K
Sbjct: 220 ARSDVLTLDILDVVTT----DPPPDVHVSRVGGLEDQLSVRWVSPPA---LKDFLFQAK- 271
Query: 277 HNTRNGYLQIEKLMTNAFISIIDDLSK--------------YDVQVRAAVSSM--CREAG 320
Y ++ + ++DD+S Y VQVR + ++AG
Sbjct: 272 ------YQIRYRVEDSVDWKVVDDVSNQTSCRLAGLKPGTVYFVQVRCNPFGIYGSKKAG 325
Query: 321 LWSEWSQP 328
+WSEWS P
Sbjct: 326 IWSEWSHP 333
>gi|51093381 leptin receptor isoform 3 [Homo sapiens]
Length = 958
Score = 38.9 bits (89), Expect = 0.009
Identities = 28/94 (29%), Positives = 44/94 (46%), Gaps = 11/94 (11%)
Query: 240 NPPLNVTAEI-EGTRLSIQWEKP-VSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISI 297
+PPL + EI + L I W P + FP+ Y+VK ++ + +A +
Sbjct: 238 DPPLGLHMEITDDGNLKISWSSPPLVPFPLQ---YQVKYSENSTTVIREADKIVSATSLL 294
Query: 298 IDDL---SKYDVQVRAAVSSMCREAGLWSEWSQP 328
+D + S Y+VQVR G+WS+WS P
Sbjct: 295 VDSILPGSSYEVQVRG---KRLDGPGIWSDWSTP 325
Score = 37.7 bits (86), Expect = 0.020
Identities = 56/232 (24%), Positives = 86/232 (37%), Gaps = 43/232 (18%)
Query: 130 VNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGT--DAPEDTQYFLYYRYGSWTEECQEYS- 186
+N++C T+ Y + C W T E T Y+R + +
Sbjct: 432 INISCETD----------GYLTKMTCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHP 481
Query: 187 ----KDTLGRN---IACWFPRTFILSKGRDWLAV---LVNGSSKHSAIRPFDQLFALHAI 236
KD ++ C F F+LS W+ + L + S + + P + L
Sbjct: 482 ISEPKDCYLQSDGFYECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPL--- 538
Query: 237 DQINPPLNVTAEIEGT--RLSIQWEKPVSAFPIHCFDYEVKIHNTRNG-----YLQIEKL 289
PP +V AEI L I WEKPV FP + ++++ + Y +
Sbjct: 539 ----PPSSVKAEITINIGLLKISWEKPV--FPENNLQFQIRYGLSGKEVQWKMYEVYDAK 592
Query: 290 MTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIY-VGNDEHKPLR 340
+ + + D + Y VQVR G WS WS P Y V D P+R
Sbjct: 593 SKSVSLPVPDLCAVYAVQVRC---KRLDGLGYWSNWSNPAYTVVMDIKVPMR 641
>gi|51093379 leptin receptor isoform 2 [Homo sapiens]
Length = 896
Score = 38.9 bits (89), Expect = 0.009
Identities = 28/94 (29%), Positives = 44/94 (46%), Gaps = 11/94 (11%)
Query: 240 NPPLNVTAEI-EGTRLSIQWEKP-VSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISI 297
+PPL + EI + L I W P + FP+ Y+VK ++ + +A +
Sbjct: 238 DPPLGLHMEITDDGNLKISWSSPPLVPFPLQ---YQVKYSENSTTVIREADKIVSATSLL 294
Query: 298 IDDL---SKYDVQVRAAVSSMCREAGLWSEWSQP 328
+D + S Y+VQVR G+WS+WS P
Sbjct: 295 VDSILPGSSYEVQVRG---KRLDGPGIWSDWSTP 325
Score = 37.7 bits (86), Expect = 0.020
Identities = 56/232 (24%), Positives = 86/232 (37%), Gaps = 43/232 (18%)
Query: 130 VNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGT--DAPEDTQYFLYYRYGSWTEECQEYS- 186
+N++C T+ Y + C W T E T Y+R + +
Sbjct: 432 INISCETD----------GYLTKMTCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHP 481
Query: 187 ----KDTLGRN---IACWFPRTFILSKGRDWLAV---LVNGSSKHSAIRPFDQLFALHAI 236
KD ++ C F F+LS W+ + L + S + + P + L
Sbjct: 482 ISEPKDCYLQSDGFYECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPL--- 538
Query: 237 DQINPPLNVTAEIEGT--RLSIQWEKPVSAFPIHCFDYEVKIHNTRNG-----YLQIEKL 289
PP +V AEI L I WEKPV FP + ++++ + Y +
Sbjct: 539 ----PPSSVKAEITINIGLLKISWEKPV--FPENNLQFQIRYGLSGKEVQWKMYEVYDAK 592
Query: 290 MTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIY-VGNDEHKPLR 340
+ + + D + Y VQVR G WS WS P Y V D P+R
Sbjct: 593 SKSVSLPVPDLCAVYAVQVRC---KRLDGLGYWSNWSNPAYTVVMDIKVPMR 641
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,081,990
Number of Sequences: 37866
Number of extensions: 746081
Number of successful extensions: 2070
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 1975
Number of HSP's gapped (non-prelim): 90
length of query: 420
length of database: 18,247,518
effective HSP length: 105
effective length of query: 315
effective length of database: 14,271,588
effective search space: 4495550220
effective search space used: 4495550220
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.