Search of human proteins with 28558979

Search of human proteins with 28558979

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|28558979 mediator complex subunit 27 [Homo sapiens]
         (311 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|28558979 mediator complex subunit 27 [Homo sapiens]                625   e-179
gi|169178509 PREDICTED: similar to cofactor required for Sp1 tra...   316   1e-86
gi|169178511 PREDICTED: similar to cofactor required for Sp1 tra...   231   5e-61
gi|115298684 polypeptide N-acetylgalactosaminyltransferase 6 [Ho...    30   2.1  
gi|89145413 short stature homeobox 2 isoform a [Homo sapiens]          30   3.6  
gi|19923559 EMSY protein [Homo sapiens]                                29   6.1  
gi|51093836 hypothetical protein LOC126859 isoform 1 [Homo sapiens]    29   6.1  
gi|51093834 hypothetical protein LOC126859 isoform 2 [Homo sapiens]    29   6.1  
gi|54859722 nucleoporin 160kDa [Homo sapiens]                          29   6.1  
gi|163838631 retinoblastoma-associated protein 140 isoform a [Ho...    29   6.1  
gi|163838629 retinoblastoma-associated protein 140 isoform b [Ho...    29   6.1  
gi|21450808 PARK2 co-regulated-like isoform 1 [Homo sapiens]           28   8.0  

>gi|28558979 mediator complex subunit 27 [Homo sapiens]
          Length = 311

 Score =  625 bits (1611), Expect = e-179
 Identities = 311/311 (100%), Positives = 311/311 (100%)

Query: 1   MADVINVSVNLEAFSQAISAIQALRSSVSRVFDCLKDGMRNKETLEGREKAFIAHFQDNL 60
           MADVINVSVNLEAFSQAISAIQALRSSVSRVFDCLKDGMRNKETLEGREKAFIAHFQDNL
Sbjct: 1   MADVINVSVNLEAFSQAISAIQALRSSVSRVFDCLKDGMRNKETLEGREKAFIAHFQDNL 60

Query: 61  HSVNRDLNELERLSNLVGKPSENHPLHNSGLLSLDPVQDKTPLYSQLLQAYKWSNKLQYH 120
           HSVNRDLNELERLSNLVGKPSENHPLHNSGLLSLDPVQDKTPLYSQLLQAYKWSNKLQYH
Sbjct: 61  HSVNRDLNELERLSNLVGKPSENHPLHNSGLLSLDPVQDKTPLYSQLLQAYKWSNKLQYH 120

Query: 121 AGLASGLLNQQSLKRSANQMGVSAKRRPKAQPTTLVLPPQYVDDVISRIDRMFPEMSIHL 180
           AGLASGLLNQQSLKRSANQMGVSAKRRPKAQPTTLVLPPQYVDDVISRIDRMFPEMSIHL
Sbjct: 121 AGLASGLLNQQSLKRSANQMGVSAKRRPKAQPTTLVLPPQYVDDVISRIDRMFPEMSIHL 180

Query: 181 SRPNGTSAMLLVTLGKVLKVIVVMRSLFIDRTIVKGYNENVYTEDGKLDIWSKSNYQVFQ 240
           SRPNGTSAMLLVTLGKVLKVIVVMRSLFIDRTIVKGYNENVYTEDGKLDIWSKSNYQVFQ
Sbjct: 181 SRPNGTSAMLLVTLGKVLKVIVVMRSLFIDRTIVKGYNENVYTEDGKLDIWSKSNYQVFQ 240

Query: 241 KVTDHATTALLHYQLPQMPDVVVRSFMTWLRSYIKLFQAPCQRCGKFLQDGLPPTWRDFR 300
           KVTDHATTALLHYQLPQMPDVVVRSFMTWLRSYIKLFQAPCQRCGKFLQDGLPPTWRDFR
Sbjct: 241 KVTDHATTALLHYQLPQMPDVVVRSFMTWLRSYIKLFQAPCQRCGKFLQDGLPPTWRDFR 300

Query: 301 TLEAFHDTCRQ 311
           TLEAFHDTCRQ
Sbjct: 301 TLEAFHDTCRQ 311


>gi|169178509 PREDICTED: similar to cofactor required for Sp1
           transcriptional activation, subunit 8, 34kDa isoform 2
           [Homo sapiens]
          Length = 160

 Score =  316 bits (810), Expect = 1e-86
 Identities = 160/160 (100%), Positives = 160/160 (100%)

Query: 1   MADVINVSVNLEAFSQAISAIQALRSSVSRVFDCLKDGMRNKETLEGREKAFIAHFQDNL 60
           MADVINVSVNLEAFSQAISAIQALRSSVSRVFDCLKDGMRNKETLEGREKAFIAHFQDNL
Sbjct: 1   MADVINVSVNLEAFSQAISAIQALRSSVSRVFDCLKDGMRNKETLEGREKAFIAHFQDNL 60

Query: 61  HSVNRDLNELERLSNLVGKPSENHPLHNSGLLSLDPVQDKTPLYSQLLQAYKWSNKLQYH 120
           HSVNRDLNELERLSNLVGKPSENHPLHNSGLLSLDPVQDKTPLYSQLLQAYKWSNKLQYH
Sbjct: 61  HSVNRDLNELERLSNLVGKPSENHPLHNSGLLSLDPVQDKTPLYSQLLQAYKWSNKLQYH 120

Query: 121 AGLASGLLNQQSLKRSANQMGVSAKRRPKAQPTTLVLPPQ 160
           AGLASGLLNQQSLKRSANQMGVSAKRRPKAQPTTLVLPPQ
Sbjct: 121 AGLASGLLNQQSLKRSANQMGVSAKRRPKAQPTTLVLPPQ 160


>gi|169178511 PREDICTED: similar to cofactor required for Sp1
           transcriptional activation, subunit 8, 34kDa isoform 1
           [Homo sapiens]
          Length = 130

 Score =  231 bits (590), Expect = 5e-61
 Identities = 116/116 (100%), Positives = 116/116 (100%)

Query: 1   MADVINVSVNLEAFSQAISAIQALRSSVSRVFDCLKDGMRNKETLEGREKAFIAHFQDNL 60
           MADVINVSVNLEAFSQAISAIQALRSSVSRVFDCLKDGMRNKETLEGREKAFIAHFQDNL
Sbjct: 1   MADVINVSVNLEAFSQAISAIQALRSSVSRVFDCLKDGMRNKETLEGREKAFIAHFQDNL 60

Query: 61  HSVNRDLNELERLSNLVGKPSENHPLHNSGLLSLDPVQDKTPLYSQLLQAYKWSNK 116
           HSVNRDLNELERLSNLVGKPSENHPLHNSGLLSLDPVQDKTPLYSQLLQAYKWSNK
Sbjct: 61  HSVNRDLNELERLSNLVGKPSENHPLHNSGLLSLDPVQDKTPLYSQLLQAYKWSNK 116


>gi|115298684 polypeptide N-acetylgalactosaminyltransferase 6 [Homo
           sapiens]
          Length = 622

 Score = 30.4 bits (67), Expect = 2.1
 Identities = 23/97 (23%), Positives = 41/97 (42%), Gaps = 18/97 (18%)

Query: 212 TIVKGYNENVYTEDGKLDIWSKSN----YQVFQ----------KVTDHATTALLHYQLPQ 257
           +I K Y E++ T D +++IW   N    ++V+Q           V  H       +  P+
Sbjct: 360 SISKSYFEHIGTYDNQMEIWGGENVEMSFRVWQCGGQLEIIPCSVVGHVFRTKSPHTFPK 419

Query: 258 MPDVVVRSFM----TWLRSYIKLFQAPCQRCGKFLQD 290
              V+ R+ +     W+ SY K+F     +  K  Q+
Sbjct: 420 GTSVIARNQVRLAEVWMDSYKKIFYRRNLQAAKMAQE 456


>gi|89145413 short stature homeobox 2 isoform a [Homo sapiens]
          Length = 331

 Score = 29.6 bits (65), Expect = 3.6
 Identities = 31/125 (24%), Positives = 49/125 (39%), Gaps = 2/125 (1%)

Query: 35  LKDGMRNKETLEGREKAFIAHFQDNLHSVNRDLNELERLSNLVGKPSENHPLHNSGLLSL 94
           LKD   + + +E   +  I   +   +     LNELERL +    P        S  L L
Sbjct: 120 LKDRKEDAKGMEDEGQTKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGL 179

Query: 95  DPVQDKTPLYSQLLQAYKWSNKLQYHAGLASGLLNQQSLKRSANQMGVSAKRRPKAQPTT 154
              + +    ++  +  K  N+L  H G+  G  +Q    R A  + V A R P  Q + 
Sbjct: 180 SEARVQVWFQNRRAKCRKQENQL--HKGVLIGAASQFEACRVAPYVNVGALRMPFQQDSH 237

Query: 155 LVLPP 159
             + P
Sbjct: 238 CNVTP 242


>gi|19923559 EMSY protein [Homo sapiens]
          Length = 1322

 Score = 28.9 bits (63), Expect = 6.1
 Identities = 14/41 (34%), Positives = 22/41 (53%)

Query: 224  EDGKLDIWSKSNYQVFQKVTDHATTALLHYQLPQMPDVVVR 264
            E  +L + +   +Q  QK T H     L ++LPQMP + +R
Sbjct: 960  EQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIR 1000


>gi|51093836 hypothetical protein LOC126859 isoform 1 [Homo sapiens]
          Length = 1012

 Score = 28.9 bits (63), Expect = 6.1
 Identities = 14/58 (24%), Positives = 30/58 (51%)

Query: 133 LKRSANQMGVSAKRRPKAQPTTLVLPPQYVDDVISRIDRMFPEMSIHLSRPNGTSAML 190
           L+ +   +G+    R K+    +    QY++++I  I +++ E  I ++  NG S +L
Sbjct: 548 LQENWADIGLGIFNRHKSLEGEMPSERQYMEEIIKNIQKLYKEYEIRINGDNGYSKIL 605


>gi|51093834 hypothetical protein LOC126859 isoform 2 [Homo sapiens]
          Length = 938

 Score = 28.9 bits (63), Expect = 6.1
 Identities = 14/58 (24%), Positives = 30/58 (51%)

Query: 133 LKRSANQMGVSAKRRPKAQPTTLVLPPQYVDDVISRIDRMFPEMSIHLSRPNGTSAML 190
           L+ +   +G+    R K+    +    QY++++I  I +++ E  I ++  NG S +L
Sbjct: 548 LQENWADIGLGIFNRHKSLEGEMPSERQYMEEIIKNIQKLYKEYEIRINGDNGYSKIL 605


>gi|54859722 nucleoporin 160kDa [Homo sapiens]
          Length = 1436

 Score = 28.9 bits (63), Expect = 6.1
 Identities = 28/121 (23%), Positives = 54/121 (44%), Gaps = 21/121 (17%)

Query: 178 IHLSRPNGTSAMLLVTLGKVLKVIVVMRS-LFIDRTIVKGYNENVYTEDGKLDIWSKSNY 236
           +++S       +L++T   V ++++   S ++    +V    ++++T+ GK+D     NY
Sbjct: 142 VYVSETQNRVIILMLTNQTVHRLLLPHPSRMYRSELVVDSQMQSIFTDIGKVDFTDPCNY 201

Query: 237 QVFQKVTDHATTALLHYQLPQMPDVVVRSFMT--WLRSYIK-LFQAPCQRCGKFLQDGLP 293
           Q+                +P +P +   S  +  WL S  + LF  PC   G F+   LP
Sbjct: 202 QL----------------IPAVPGISPNSTASTAWLSSDGEALFALPCASGGIFVLK-LP 244

Query: 294 P 294
           P
Sbjct: 245 P 245


>gi|163838631 retinoblastoma-associated protein 140 isoform a [Homo
           sapiens]
          Length = 1512

 Score = 28.9 bits (63), Expect = 6.1
 Identities = 38/164 (23%), Positives = 67/164 (40%), Gaps = 16/164 (9%)

Query: 35  LKDGMRNKETLEGREKAFIAHFQDNLHSVNRDLNELERLSNLVGKPSENHPLHNSGLLSL 94
           +K G RN      R +A I+  Q + HS++ D + ++ L NL+    +       G    
Sbjct: 650 MKFGKRNNS----RGEAIISGKQRSSHSLDYDKDRVKELINLI----QCRKKSVGGDSDT 701

Query: 95  DPVQDKTPLYSQLLQAYKWSNKLQYHAGLASGLLNQQSLKRSANQMGVSAKRRPKAQPTT 154
           + ++ KT L  +L    +   KL   + L+      +   +    +G  A  R + Q T 
Sbjct: 702 EDMRSKTVLKRKLEDLPENMRKLAKTSNLSENCHLYEESPQPIGSLGHDADLRRQQQDT- 760

Query: 155 LVLPPQYVDDVISRIDRMFPEMSIHLSRPNGTSAMLLVTLGKVL 198
                   +  I+ I R+F  +S  L+    + A L  T+ K L
Sbjct: 761 -------CNSGIADIHRLFNWLSETLANARHSDASLTDTVNKAL 797


>gi|163838629 retinoblastoma-associated protein 140 isoform b [Homo
           sapiens]
          Length = 1233

 Score = 28.9 bits (63), Expect = 6.1
 Identities = 38/164 (23%), Positives = 67/164 (40%), Gaps = 16/164 (9%)

Query: 35  LKDGMRNKETLEGREKAFIAHFQDNLHSVNRDLNELERLSNLVGKPSENHPLHNSGLLSL 94
           +K G RN      R +A I+  Q + HS++ D + ++ L NL+    +       G    
Sbjct: 254 MKFGKRNNS----RGEAIISGKQRSSHSLDYDKDRVKELINLI----QCRKKSVGGDSDT 305

Query: 95  DPVQDKTPLYSQLLQAYKWSNKLQYHAGLASGLLNQQSLKRSANQMGVSAKRRPKAQPTT 154
           + ++ KT L  +L    +   KL   + L+      +   +    +G  A  R + Q T 
Sbjct: 306 EDMRSKTVLKRKLEDLPENMRKLAKTSNLSENCHLYEESPQPIGSLGHDADLRRQQQDT- 364

Query: 155 LVLPPQYVDDVISRIDRMFPEMSIHLSRPNGTSAMLLVTLGKVL 198
                   +  I+ I R+F  +S  L+    + A L  T+ K L
Sbjct: 365 -------CNSGIADIHRLFNWLSETLANARHSDASLTDTVNKAL 401


>gi|21450808 PARK2 co-regulated-like isoform 1 [Homo sapiens]
          Length = 221

 Score = 28.5 bits (62), Expect = 8.0
 Identities = 19/58 (32%), Positives = 27/58 (46%), Gaps = 2/58 (3%)

Query: 50  KAFIAHFQDNLHSVNRDLNELERLSNLVGKPSENHPLHNSGLLSLDPVQDKTPLYSQL 107
           KA + H  D +    R LN L +LS +VG    +H  H     SL  ++ K P Y  +
Sbjct: 164 KAALVHSDDEVFE--RGLNALVQLSVVVGPSLNDHLKHLLTSGSLSIIKSKIPTYCSI 219


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.134    0.395 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,104,689
Number of Sequences: 37866
Number of extensions: 462834
Number of successful extensions: 1215
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1208
Number of HSP's gapped (non-prelim): 12
length of query: 311
length of database: 18,247,518
effective HSP length: 102
effective length of query: 209
effective length of database: 14,385,186
effective search space: 3006503874
effective search space used: 3006503874
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.