Search of human proteins with 28376627

Search of human proteins with 28376627

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|28376627 synaptotagmin IX [Homo sapiens]
         (491 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|28376627 synaptotagmin IX [Homo sapiens]                          1012   0.0  
gi|39752671 synaptotagmin X [Homo sapiens]                            595   e-170
gi|45504376 synaptotagmin VI [Homo sapiens]                           531   e-151
gi|238550198 synaptotagmin III [Homo sapiens]                         457   e-129
gi|238550196 synaptotagmin III [Homo sapiens]                         457   e-129
gi|14150054 synaptotagmin III [Homo sapiens]                          457   e-129
gi|209447073 synaptotagmin I [Homo sapiens]                           286   4e-77
gi|5032139 synaptotagmin I [Homo sapiens]                             286   4e-77
gi|209447070 synaptotagmin I [Homo sapiens]                           286   4e-77
gi|211059429 synaptotagmin II [Homo sapiens]                          281   1e-75
gi|31543670 synaptotagmin II [Homo sapiens]                           281   1e-75
gi|92859638 synaptotagmin V [Homo sapiens]                            274   1e-73
gi|38570146 synaptotagmin VII [Homo sapiens]                          247   2e-65
gi|24308219 synaptotagmin IV [Homo sapiens]                           216   4e-56
gi|216548478 synaptotagmin XI [Homo sapiens]                          207   2e-53
gi|40068038 B/K protein [Homo sapiens]                                186   4e-47
gi|31881675 synaptotagmin XV isoform a [Homo sapiens]                 169   5e-42
gi|94536846 synaptotagmin VIII [Homo sapiens]                         166   6e-41
gi|29366828 synaptotagmin XII [Homo sapiens]                          155   8e-38
gi|31881667 synaptotagmin XV isoform b [Homo sapiens]                 146   5e-35
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]            144   1e-34
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]             144   1e-34
gi|47078261 double C2-like domains, alpha [Homo sapiens]              140   3e-33
gi|24308233 synaptotagmin XIII [Homo sapiens]                         139   8e-33
gi|6005997 double C2-like domains, beta [Homo sapiens]                136   4e-32
gi|193804862 synaptotagmin-like 4 [Homo sapiens]                      117   2e-26
gi|193804860 synaptotagmin-like 4 [Homo sapiens]                      117   2e-26
gi|123173752 synaptotagmin XIV-like [Homo sapiens]                    115   9e-26
gi|239744413 PREDICTED: hypothetical protein LOC390213 [Homo sap...   108   1e-23
gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens]            102   6e-22

>gi|28376627 synaptotagmin IX [Homo sapiens]
          Length = 491

 Score = 1012 bits (2616), Expect = 0.0
 Identities = 491/491 (100%), Positives = 491/491 (100%)

Query: 1   MPGARDALCHQALQLLAELCARGALEHDSCQDFIYHLRDRARPRLRDPDISVSLLTLVVT 60
           MPGARDALCHQALQLLAELCARGALEHDSCQDFIYHLRDRARPRLRDPDISVSLLTLVVT
Sbjct: 1   MPGARDALCHQALQLLAELCARGALEHDSCQDFIYHLRDRARPRLRDPDISVSLLTLVVT 60

Query: 61  ACGLALFGVSLFVSWKLCWVPWRERGLPSGSKDNNQEPLNYMDTETNEQENSEDFLDPPT 120
           ACGLALFGVSLFVSWKLCWVPWRERGLPSGSKDNNQEPLNYMDTETNEQENSEDFLDPPT
Sbjct: 61  ACGLALFGVSLFVSWKLCWVPWRERGLPSGSKDNNQEPLNYMDTETNEQENSEDFLDPPT 120

Query: 121 PCPDSSMKISHTSPDIPLSTQTGIQENCAHGVRVQRQVTEPTSSARHNSIRRQLNLSNPD 180
           PCPDSSMKISHTSPDIPLSTQTGIQENCAHGVRVQRQVTEPTSSARHNSIRRQLNLSNPD
Sbjct: 121 PCPDSSMKISHTSPDIPLSTQTGIQENCAHGVRVQRQVTEPTSSARHNSIRRQLNLSNPD 180

Query: 181 FNIQQLQKQEQLTGIGRIKPELYKQRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVK 240
           FNIQQLQKQEQLTGIGRIKPELYKQRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVK
Sbjct: 181 FNIQQLQKQEQLTGIGRIKPELYKQRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVK 240

Query: 241 IHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEA 300
           IHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEA
Sbjct: 241 IHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEA 300

Query: 301 RKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWKDIEYVTNDNVDLGELMFSL 360
           RKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWKDIEYVTNDNVDLGELMFSL
Sbjct: 301 RKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWKDIEYVTNDNVDLGELMFSL 360

Query: 361 CYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYN 420
           CYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYN
Sbjct: 361 CYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYN 420

Query: 421 EAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGRDHWSEMLSYPRKP 480
           EAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGRDHWSEMLSYPRKP
Sbjct: 421 EAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGRDHWSEMLSYPRKP 480

Query: 481 IAHWHSLVEKR 491
           IAHWHSLVEKR
Sbjct: 481 IAHWHSLVEKR 491


>gi|39752671 synaptotagmin X [Homo sapiens]
          Length = 523

 Score =  595 bits (1535), Expect = e-170
 Identities = 294/494 (59%), Positives = 371/494 (75%), Gaps = 13/494 (2%)

Query: 6   DALCHQALQLLAELCARGALEHDSCQDFIYHLRDRARPRLRDPDISVSLLTLVVTACGLA 65
           ++LC +AL ++ ELC  G +E + C       RDR        DISVSLL +VV+ CGLA
Sbjct: 10  NSLCQKALHIVTELCFAGQVEWEKCSGIFP--RDRGSQGGSSTDISVSLLAVVVSFCGLA 67

Query: 66  LFGVSLFVSWKLCWVPWRERGLPSGSKDNNQEPLNYMDTETNEQENSEDFLD---PPTPC 122
           L  VSLFV WKLCW  W+ + + S      Q  ++   TE  E E  ++  +   P    
Sbjct: 68  LLVVSLFVFWKLCWPCWKSKPVTSNITTLPQS-ISSAPTEVFETEEKKEIKENEKPAVKA 126

Query: 123 PDSSMKISHTSPDIPLSTQTGIQENCAHGVRVQRQVTEPTSSARHNSIRR----QLNLSN 178
            + ++KISHTSPDIP   QT ++E+     RVQRQ+TEPTSS RH+S RR    Q+ +S+
Sbjct: 127 IEPAIKISHTSPDIPAEVQTALKEHLIKHARVQRQITEPTSSTRHSSFRRHLPRQMQVSS 186

Query: 179 PDFNIQQ---LQKQEQLTGIGRIKPELYKQRSLDNDDGRRSNSKACGKLNFILKYDCDLE 235
            DF++     LQ+ E  T IGRIKPELYKQ+S+D++  +  + K CGKLNF L+YD + E
Sbjct: 187 VDFSMGTEPVLQRGETTTSIGRIKPELYKQKSVDSEGNQNEDVKICGKLNFTLQYDYENE 246

Query: 236 QLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVPY 295
            L+VKI KA++LPAKDF+GTSDPYVK+YLLPDRK K QT+VHRKTLNP+FDE F FPV Y
Sbjct: 247 LLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDRKKKFQTRVHRKTLNPLFDETFQFPVAY 306

Query: 296 NDLEARKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWKDIEYVTNDNVDLGE 355
           + L  RKLHFSVYDFDRFSRHD+IG+V++D+  +++D  RE  +WKDI   T +++DLGE
Sbjct: 307 DQLSNRKLHFSVYDFDRFSRHDMIGEVILDNLFEVSDLSREATVWKDIHCATTESIDLGE 366

Query: 356 LMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTL 415
           +MFSLCYLPTAGR+T+T+IK RNLKAMDITG+SDPYVKVSLMC+GRRLKKRKT+TK+NTL
Sbjct: 367 IMFSLCYLPTAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTL 426

Query: 416 NPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGRDHWSEMLS 475
           NPVYNEAI+FD+PPEN+DQ+ LSIAVMDYDRVGHNE+IGVC+ G +AE LGRDHW+EML+
Sbjct: 427 NPVYNEAIIFDIPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLDAEGLGRDHWNEMLA 486

Query: 476 YPRKPIAHWHSLVE 489
           Y RKPI HWH L+E
Sbjct: 487 YHRKPITHWHPLLE 500


>gi|45504376 synaptotagmin VI [Homo sapiens]
          Length = 425

 Score =  531 bits (1369), Expect = e-151
 Identities = 258/415 (62%), Positives = 322/415 (77%), Gaps = 7/415 (1%)

Query: 80  VPWRERGLPSGSKDNNQEPLNYMDTETNEQENSEDFLDPPT-PCPDSSMKISHTSPDIPL 138
           +PWR +   S S  N   PL  + + +     ++   DP T    ++++KISHTSPDIP 
Sbjct: 1   MPWRNKEASSPSSAN--PPLEALQSPSFRGNMADKLKDPSTLGFLEAAVKISHTSPDIPA 58

Query: 139 STQTGIQENCAHGVRVQRQVTEPTSSARHNSIRR----QLNLSNPDFNIQQLQKQEQLTG 194
             Q  ++E+     R+QRQ TEP SS RH S +R    Q+++S+ D+  +     EQ T 
Sbjct: 59  EVQMSVKEHIMRHTRLQRQTTEPASSTRHTSFKRHLPRQMHVSSVDYGNELPPAAEQPTS 118

Query: 195 IGRIKPELYKQRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSG 254
           IGRIKPELYKQ+S+D +D +   +K+CGK+NF L+YD + E LIV+I KA +LPAKDF G
Sbjct: 119 IGRIKPELYKQKSVDGEDAKSEATKSCGKINFSLRYDYETETLIVRILKAFDLPAKDFCG 178

Query: 255 TSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFS 314
           +SDPYVKIYLLPDRK K QT+VHRKTLNP FDE F FPVPY +L  RKLH SV+DFDRFS
Sbjct: 179 SSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRFS 238

Query: 315 RHDLIGQVVVDHFLDLADFPRECILWKDIEYVTNDNVDLGELMFSLCYLPTAGRLTITII 374
           RHD+IG+V++D+  + +D  RE  +WKDI+Y T+++VDLGE+MFSLCYLPTAGRLT+T+I
Sbjct: 239 RHDMIGEVILDNLFEASDLSRETSIWKDIQYATSESVDLGEIMFSLCYLPTAGRLTLTVI 298

Query: 375 KARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQ 434
           K RNLKAMDITG SDPYVKVSL+CDGRRLKK+KT+ K+NTLNPVYNEAI+FD+PPEN+DQ
Sbjct: 299 KCRNLKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQ 358

Query: 435 IHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGRDHWSEMLSYPRKPIAHWHSLVE 489
           + L I+VMDYDRVGHNEIIGVC+VG  AE LGRDHW+EML+YPRKPIAHWHSLVE
Sbjct: 359 VSLLISVMDYDRVGHNEIIGVCRVGITAEGLGRDHWNEMLAYPRKPIAHWHSLVE 413


>gi|238550198 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  457 bits (1177), Expect = e-129
 Identities = 268/570 (47%), Positives = 346/570 (60%), Gaps = 89/570 (15%)

Query: 6   DALCHQALQLLAELCAR--GALEHDSCQDFIYHLRDRARPRLRDPDISVSLLTLVVTACG 63
           D LC +AL L+++LCAR   A  +D CQ+F  + R R  PR  D DISVSLL+++VT CG
Sbjct: 7   DDLCRRALILVSDLCARVRDADTNDRCQEF--NDRIRGYPRGPDADISVSLLSVIVTFCG 64

Query: 64  LALFGVSLFVSWKLCWVPWRER---------------------GLPSGSKDNNQ------ 96
           + L GVSLFVSWKLCWVPWR++                     GL  G   +        
Sbjct: 65  IVLLGVSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLGPGVGLAGLVGGGGHHLAAGLGGH 124

Query: 97  ----------------------EP--LNYMDTETNEQENSEDFLDPPTPCPDSSMKISHT 132
                                 EP  L   DT      + + + +       + +K S T
Sbjct: 125 PLLGGPHHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVKPSQT 184

Query: 133 SPDIPLSTQTGI-------QENCAHGVRVQRQVTEPTSSARHNSIRRQLN----LSNPDF 181
           SP++P     G                +  +QVT    + R+ ++ R L      S PD 
Sbjct: 185 SPELPSEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTSQPDP 244

Query: 182 NIQQLQK---------QEQLTGIGRIKPELYKQRSLDNDDGRRSNS----------KACG 222
           + ++            +E+   IG+IKPELY+        GRRS              CG
Sbjct: 245 SSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTG---PGGRRSGGGPGSGEAGTGAPCG 301

Query: 223 KLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLN 282
           +++F L+Y    +QL+V+I +A++LPAKD +G SDPYVKIYLLPDRK K QTKVHRKTLN
Sbjct: 302 RISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLN 361

Query: 283 PVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWKD 342
           PVF+E F F VP  +L  RKLHFSVYDFDRFSRHDLIGQVV+D+ L+LA+ P +  LW+D
Sbjct: 362 PVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRD 421

Query: 343 IEYVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRR 402
           I    ++  DLGEL FSLCYLPTAGRLT+TIIKA NLKAMD+TG SDPYVK SL+ +GRR
Sbjct: 422 IVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRR 481

Query: 403 LKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVG-NE 461
           LKKRKTS K+NTLNP YNEA+VFDV PE+++ + LSIAV+DYD +GHNE+IGVC+VG + 
Sbjct: 482 LKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDA 541

Query: 462 AERLGRDHWSEMLSYPRKPIAHWHSLVEKR 491
           A+  GR+HW+EML+ PRKP+ HWH LVE++
Sbjct: 542 ADPHGREHWAEMLANPRKPVEHWHQLVEEK 571


>gi|238550196 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  457 bits (1177), Expect = e-129
 Identities = 268/570 (47%), Positives = 346/570 (60%), Gaps = 89/570 (15%)

Query: 6   DALCHQALQLLAELCAR--GALEHDSCQDFIYHLRDRARPRLRDPDISVSLLTLVVTACG 63
           D LC +AL L+++LCAR   A  +D CQ+F  + R R  PR  D DISVSLL+++VT CG
Sbjct: 7   DDLCRRALILVSDLCARVRDADTNDRCQEF--NDRIRGYPRGPDADISVSLLSVIVTFCG 64

Query: 64  LALFGVSLFVSWKLCWVPWRER---------------------GLPSGSKDNNQ------ 96
           + L GVSLFVSWKLCWVPWR++                     GL  G   +        
Sbjct: 65  IVLLGVSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLGPGVGLAGLVGGGGHHLAAGLGGH 124

Query: 97  ----------------------EP--LNYMDTETNEQENSEDFLDPPTPCPDSSMKISHT 132
                                 EP  L   DT      + + + +       + +K S T
Sbjct: 125 PLLGGPHHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVKPSQT 184

Query: 133 SPDIPLSTQTGI-------QENCAHGVRVQRQVTEPTSSARHNSIRRQLN----LSNPDF 181
           SP++P     G                +  +QVT    + R+ ++ R L      S PD 
Sbjct: 185 SPELPSEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTSQPDP 244

Query: 182 NIQQLQK---------QEQLTGIGRIKPELYKQRSLDNDDGRRSNS----------KACG 222
           + ++            +E+   IG+IKPELY+        GRRS              CG
Sbjct: 245 SSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTG---PGGRRSGGGPGSGEAGTGAPCG 301

Query: 223 KLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLN 282
           +++F L+Y    +QL+V+I +A++LPAKD +G SDPYVKIYLLPDRK K QTKVHRKTLN
Sbjct: 302 RISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLN 361

Query: 283 PVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWKD 342
           PVF+E F F VP  +L  RKLHFSVYDFDRFSRHDLIGQVV+D+ L+LA+ P +  LW+D
Sbjct: 362 PVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRD 421

Query: 343 IEYVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRR 402
           I    ++  DLGEL FSLCYLPTAGRLT+TIIKA NLKAMD+TG SDPYVK SL+ +GRR
Sbjct: 422 IVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRR 481

Query: 403 LKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVG-NE 461
           LKKRKTS K+NTLNP YNEA+VFDV PE+++ + LSIAV+DYD +GHNE+IGVC+VG + 
Sbjct: 482 LKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDA 541

Query: 462 AERLGRDHWSEMLSYPRKPIAHWHSLVEKR 491
           A+  GR+HW+EML+ PRKP+ HWH LVE++
Sbjct: 542 ADPHGREHWAEMLANPRKPVEHWHQLVEEK 571


>gi|14150054 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  457 bits (1177), Expect = e-129
 Identities = 268/570 (47%), Positives = 346/570 (60%), Gaps = 89/570 (15%)

Query: 6   DALCHQALQLLAELCAR--GALEHDSCQDFIYHLRDRARPRLRDPDISVSLLTLVVTACG 63
           D LC +AL L+++LCAR   A  +D CQ+F  + R R  PR  D DISVSLL+++VT CG
Sbjct: 7   DDLCRRALILVSDLCARVRDADTNDRCQEF--NDRIRGYPRGPDADISVSLLSVIVTFCG 64

Query: 64  LALFGVSLFVSWKLCWVPWRER---------------------GLPSGSKDNNQ------ 96
           + L GVSLFVSWKLCWVPWR++                     GL  G   +        
Sbjct: 65  IVLLGVSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLGPGVGLAGLVGGGGHHLAAGLGGH 124

Query: 97  ----------------------EP--LNYMDTETNEQENSEDFLDPPTPCPDSSMKISHT 132
                                 EP  L   DT      + + + +       + +K S T
Sbjct: 125 PLLGGPHHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVKPSQT 184

Query: 133 SPDIPLSTQTGI-------QENCAHGVRVQRQVTEPTSSARHNSIRRQLN----LSNPDF 181
           SP++P     G                +  +QVT    + R+ ++ R L      S PD 
Sbjct: 185 SPELPSEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTSQPDP 244

Query: 182 NIQQLQK---------QEQLTGIGRIKPELYKQRSLDNDDGRRSNS----------KACG 222
           + ++            +E+   IG+IKPELY+        GRRS              CG
Sbjct: 245 SSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTG---PGGRRSGGGPGSGEAGTGAPCG 301

Query: 223 KLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLN 282
           +++F L+Y    +QL+V+I +A++LPAKD +G SDPYVKIYLLPDRK K QTKVHRKTLN
Sbjct: 302 RISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLN 361

Query: 283 PVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWKD 342
           PVF+E F F VP  +L  RKLHFSVYDFDRFSRHDLIGQVV+D+ L+LA+ P +  LW+D
Sbjct: 362 PVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRD 421

Query: 343 IEYVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRR 402
           I    ++  DLGEL FSLCYLPTAGRLT+TIIKA NLKAMD+TG SDPYVK SL+ +GRR
Sbjct: 422 IVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRR 481

Query: 403 LKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVG-NE 461
           LKKRKTS K+NTLNP YNEA+VFDV PE+++ + LSIAV+DYD +GHNE+IGVC+VG + 
Sbjct: 482 LKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDA 541

Query: 462 AERLGRDHWSEMLSYPRKPIAHWHSLVEKR 491
           A+  GR+HW+EML+ PRKP+ HWH LVE++
Sbjct: 542 ADPHGREHWAEMLANPRKPVEHWHQLVEEK 571


>gi|209447073 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  286 bits (731), Expect = 4e-77
 Identities = 138/267 (51%), Positives = 190/267 (71%), Gaps = 3/267 (1%)

Query: 222 GKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTL 281
           GKL + L YD    QL+V I +A  LPA D  GTSDPYVK++LLPD+K K +TKVHRKTL
Sbjct: 144 GKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTL 203

Query: 282 NPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWK 341
           NPVF+E F F VPY++L  + L  +VYDFDRFS+HD+IG+  V   ++  DF      W+
Sbjct: 204 NPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVP--MNTVDFGHVTEEWR 261

Query: 342 DIEYVTNDNVD-LGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDG 400
           D++    +  + LG++ FSL Y+PTAG+LT+ I++A+NLK MD+ G SDPYVK+ LM +G
Sbjct: 262 DLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNG 321

Query: 401 RRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGN 460
           +RLKK+KT+ K+NTLNP YNE+  F+VP E I ++ + + V+DYD++G N+ IG   VG 
Sbjct: 322 KRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGY 381

Query: 461 EAERLGRDHWSEMLSYPRKPIAHWHSL 487
            +      HWS+ML+ PR+PIA WH+L
Sbjct: 382 NSTGAELRHWSDMLANPRRPIAQWHTL 408



 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 50/125 (40%), Positives = 70/125 (56%), Gaps = 4/125 (3%)

Query: 353 LGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKR 412
           LG+L +SL Y     +L + II+A  L A+D+ G SDPYVKV L+ D  + KK +T   R
Sbjct: 143 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPD--KKKKFETKVHR 200

Query: 413 NTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGR--DHW 470
            TLNPV+NE   F VP   +    L +AV D+DR   ++IIG  +V       G   + W
Sbjct: 201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEW 260

Query: 471 SEMLS 475
            ++ S
Sbjct: 261 RDLQS 265



 Score = 76.3 bits (186), Expect = 6e-14
 Identities = 41/120 (34%), Positives = 67/120 (55%), Gaps = 2/120 (1%)

Query: 209 DNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPD- 267
           D     +   +  G + F L+Y     +L V I +A NL   D  G SDPYVKI+L+ + 
Sbjct: 262 DLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNG 321

Query: 268 -RKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVDH 326
            R  K +T + + TLNP ++E F F VP+  ++  ++  +V D+D+  ++D IG+V V +
Sbjct: 322 KRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGY 381


>gi|5032139 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  286 bits (731), Expect = 4e-77
 Identities = 138/267 (51%), Positives = 190/267 (71%), Gaps = 3/267 (1%)

Query: 222 GKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTL 281
           GKL + L YD    QL+V I +A  LPA D  GTSDPYVK++LLPD+K K +TKVHRKTL
Sbjct: 144 GKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTL 203

Query: 282 NPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWK 341
           NPVF+E F F VPY++L  + L  +VYDFDRFS+HD+IG+  V   ++  DF      W+
Sbjct: 204 NPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVP--MNTVDFGHVTEEWR 261

Query: 342 DIEYVTNDNVD-LGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDG 400
           D++    +  + LG++ FSL Y+PTAG+LT+ I++A+NLK MD+ G SDPYVK+ LM +G
Sbjct: 262 DLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNG 321

Query: 401 RRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGN 460
           +RLKK+KT+ K+NTLNP YNE+  F+VP E I ++ + + V+DYD++G N+ IG   VG 
Sbjct: 322 KRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGY 381

Query: 461 EAERLGRDHWSEMLSYPRKPIAHWHSL 487
            +      HWS+ML+ PR+PIA WH+L
Sbjct: 382 NSTGAELRHWSDMLANPRRPIAQWHTL 408



 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 50/125 (40%), Positives = 70/125 (56%), Gaps = 4/125 (3%)

Query: 353 LGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKR 412
           LG+L +SL Y     +L + II+A  L A+D+ G SDPYVKV L+ D  + KK +T   R
Sbjct: 143 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPD--KKKKFETKVHR 200

Query: 413 NTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGR--DHW 470
            TLNPV+NE   F VP   +    L +AV D+DR   ++IIG  +V       G   + W
Sbjct: 201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEW 260

Query: 471 SEMLS 475
            ++ S
Sbjct: 261 RDLQS 265



 Score = 76.3 bits (186), Expect = 6e-14
 Identities = 41/120 (34%), Positives = 67/120 (55%), Gaps = 2/120 (1%)

Query: 209 DNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPD- 267
           D     +   +  G + F L+Y     +L V I +A NL   D  G SDPYVKI+L+ + 
Sbjct: 262 DLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNG 321

Query: 268 -RKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVDH 326
            R  K +T + + TLNP ++E F F VP+  ++  ++  +V D+D+  ++D IG+V V +
Sbjct: 322 KRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGY 381


>gi|209447070 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  286 bits (731), Expect = 4e-77
 Identities = 138/267 (51%), Positives = 190/267 (71%), Gaps = 3/267 (1%)

Query: 222 GKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTL 281
           GKL + L YD    QL+V I +A  LPA D  GTSDPYVK++LLPD+K K +TKVHRKTL
Sbjct: 144 GKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTL 203

Query: 282 NPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWK 341
           NPVF+E F F VPY++L  + L  +VYDFDRFS+HD+IG+  V   ++  DF      W+
Sbjct: 204 NPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVP--MNTVDFGHVTEEWR 261

Query: 342 DIEYVTNDNVD-LGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDG 400
           D++    +  + LG++ FSL Y+PTAG+LT+ I++A+NLK MD+ G SDPYVK+ LM +G
Sbjct: 262 DLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNG 321

Query: 401 RRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGN 460
           +RLKK+KT+ K+NTLNP YNE+  F+VP E I ++ + + V+DYD++G N+ IG   VG 
Sbjct: 322 KRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGY 381

Query: 461 EAERLGRDHWSEMLSYPRKPIAHWHSL 487
            +      HWS+ML+ PR+PIA WH+L
Sbjct: 382 NSTGAELRHWSDMLANPRRPIAQWHTL 408



 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 50/125 (40%), Positives = 70/125 (56%), Gaps = 4/125 (3%)

Query: 353 LGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKR 412
           LG+L +SL Y     +L + II+A  L A+D+ G SDPYVKV L+ D  + KK +T   R
Sbjct: 143 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPD--KKKKFETKVHR 200

Query: 413 NTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGR--DHW 470
            TLNPV+NE   F VP   +    L +AV D+DR   ++IIG  +V       G   + W
Sbjct: 201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEW 260

Query: 471 SEMLS 475
            ++ S
Sbjct: 261 RDLQS 265



 Score = 76.3 bits (186), Expect = 6e-14
 Identities = 41/120 (34%), Positives = 67/120 (55%), Gaps = 2/120 (1%)

Query: 209 DNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPD- 267
           D     +   +  G + F L+Y     +L V I +A NL   D  G SDPYVKI+L+ + 
Sbjct: 262 DLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNG 321

Query: 268 -RKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVDH 326
            R  K +T + + TLNP ++E F F VP+  ++  ++  +V D+D+  ++D IG+V V +
Sbjct: 322 KRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGY 381


>gi|211059429 synaptotagmin II [Homo sapiens]
          Length = 419

 Score =  281 bits (719), Expect = 1e-75
 Identities = 135/267 (50%), Positives = 188/267 (70%), Gaps = 3/267 (1%)

Query: 222 GKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTL 281
           GKL F L YD    QL V + +A  LPA D  GTSDPYVK++LLPD+K K++TKVHRKTL
Sbjct: 141 GKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKTL 200

Query: 282 NPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWK 341
           NP F+E F F VPY +L  + L  ++YDFDRFS+HD+IG+V V   ++  D  +    W+
Sbjct: 201 NPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVP--MNTVDLGQPIEEWR 258

Query: 342 DIEYVTNDNVD-LGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDG 400
           D++    +  + LG++  SL Y+PTAG+LT+ I++A+NLK MD+ G SDPYVK+ LM +G
Sbjct: 259 DLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNG 318

Query: 401 RRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGN 460
           +RLKK+KT+ K+ TLNP +NE+  F++P E I ++ + + V+DYD++G NE IG   VG+
Sbjct: 319 KRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGS 378

Query: 461 EAERLGRDHWSEMLSYPRKPIAHWHSL 487
            A      HWS+ML+ PR+PIA WHSL
Sbjct: 379 NATGTELRHWSDMLANPRRPIAQWHSL 405



 Score = 87.4 bits (215), Expect = 3e-17
 Identities = 49/124 (39%), Positives = 74/124 (59%), Gaps = 4/124 (3%)

Query: 352 DLGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTK 411
           +LG+L FSL Y   A +LT+ +++A  L A+D+ G SDPYVKV L+ D  + KK +T   
Sbjct: 139 NLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPD--KKKKYETKVH 196

Query: 412 RNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGR--DH 469
           R TLNP +NE   F VP + +    L +A+ D+DR   ++IIG  +V      LG+  + 
Sbjct: 197 RKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEE 256

Query: 470 WSEM 473
           W ++
Sbjct: 257 WRDL 260



 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 46/141 (32%), Positives = 74/141 (52%), Gaps = 11/141 (7%)

Query: 209 DNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPD- 267
           D   G +   +  G +   L+Y     +L V I +A NL   D  G SDPYVKI+L+ + 
Sbjct: 259 DLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNG 318

Query: 268 -RKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVD- 325
            R  K +T V +KTLNP F+E F F +P+  ++  ++  +V D+D+  +++ IG++ V  
Sbjct: 319 KRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGS 378

Query: 326 --------HFLDLADFPRECI 338
                   H+ D+   PR  I
Sbjct: 379 NATGTELRHWSDMLANPRRPI 399


>gi|31543670 synaptotagmin II [Homo sapiens]
          Length = 419

 Score =  281 bits (719), Expect = 1e-75
 Identities = 135/267 (50%), Positives = 188/267 (70%), Gaps = 3/267 (1%)

Query: 222 GKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTL 281
           GKL F L YD    QL V + +A  LPA D  GTSDPYVK++LLPD+K K++TKVHRKTL
Sbjct: 141 GKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKTL 200

Query: 282 NPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWK 341
           NP F+E F F VPY +L  + L  ++YDFDRFS+HD+IG+V V   ++  D  +    W+
Sbjct: 201 NPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVP--MNTVDLGQPIEEWR 258

Query: 342 DIEYVTNDNVD-LGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDG 400
           D++    +  + LG++  SL Y+PTAG+LT+ I++A+NLK MD+ G SDPYVK+ LM +G
Sbjct: 259 DLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNG 318

Query: 401 RRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGN 460
           +RLKK+KT+ K+ TLNP +NE+  F++P E I ++ + + V+DYD++G NE IG   VG+
Sbjct: 319 KRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGS 378

Query: 461 EAERLGRDHWSEMLSYPRKPIAHWHSL 487
            A      HWS+ML+ PR+PIA WHSL
Sbjct: 379 NATGTELRHWSDMLANPRRPIAQWHSL 405



 Score = 87.4 bits (215), Expect = 3e-17
 Identities = 49/124 (39%), Positives = 74/124 (59%), Gaps = 4/124 (3%)

Query: 352 DLGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTK 411
           +LG+L FSL Y   A +LT+ +++A  L A+D+ G SDPYVKV L+ D  + KK +T   
Sbjct: 139 NLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPD--KKKKYETKVH 196

Query: 412 RNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGR--DH 469
           R TLNP +NE   F VP + +    L +A+ D+DR   ++IIG  +V      LG+  + 
Sbjct: 197 RKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEE 256

Query: 470 WSEM 473
           W ++
Sbjct: 257 WRDL 260



 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 46/141 (32%), Positives = 74/141 (52%), Gaps = 11/141 (7%)

Query: 209 DNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPD- 267
           D   G +   +  G +   L+Y     +L V I +A NL   D  G SDPYVKI+L+ + 
Sbjct: 259 DLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNG 318

Query: 268 -RKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVD- 325
            R  K +T V +KTLNP F+E F F +P+  ++  ++  +V D+D+  +++ IG++ V  
Sbjct: 319 KRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGS 378

Query: 326 --------HFLDLADFPRECI 338
                   H+ D+   PR  I
Sbjct: 379 NATGTELRHWSDMLANPRRPI 399


>gi|92859638 synaptotagmin V [Homo sapiens]
          Length = 386

 Score =  274 bits (701), Expect = 1e-73
 Identities = 135/295 (45%), Positives = 200/295 (67%), Gaps = 4/295 (1%)

Query: 195 IGRIKPELYKQRSLDNDDGRRSNSK-ACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFS 253
           I +++PE+ +     +  G++   K   G+L + L YD    QL+V I +A+ L A D  
Sbjct: 82  IDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLG 141

Query: 254 GTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRF 313
           G+SDPYV++YLLPD++ +++TKVHR+TLNP F E F F VPY +L  R L  +VYDFDRF
Sbjct: 142 GSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAVYDFDRF 201

Query: 314 SRHDLIGQVVVDHFLDLADFPRECILWKDIEYVTNDNVD-LGELMFSLCYLPTAGRLTIT 372
           SR+D IG+V V   +   D  R    W++++    +  + LG++ FSL Y+PTAG+LT+ 
Sbjct: 202 SRNDAIGEVRVP--MSSVDLGRPVQAWRELQAAPREEQEKLGDICFSLRYVPTAGKLTVI 259

Query: 373 IIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPENI 432
           +++A+NLK MD+ G SDPYVKV L+  G++++K+KT+ K+NTLNP YNEA  F+VP + +
Sbjct: 260 VLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQV 319

Query: 433 DQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGRDHWSEMLSYPRKPIAHWHSL 487
            ++ + + V+DYD++G NE IG   VG  A   G  HW++ML+ PR+PIA WHSL
Sbjct: 320 QKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADMLANPRRPIAQWHSL 374


>gi|38570146 synaptotagmin VII [Homo sapiens]
          Length = 403

 Score =  247 bits (631), Expect = 2e-65
 Identities = 126/267 (47%), Positives = 176/267 (65%), Gaps = 3/267 (1%)

Query: 222 GKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTL 281
           G++ F + Y+     L VKI KA  LPAKDFSGTSDP+VKIYLLPD+K K +TKV RK L
Sbjct: 137 GRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKNL 196

Query: 282 NPVFDEVFLFP-VPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILW 340
           NP ++E FLF   PY  +  R L+  V D+DRFSR+D IG+V +   L+  D  +    W
Sbjct: 197 NPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIP--LNKVDLTQMQTFW 254

Query: 341 KDIEYVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDG 400
           KD++  ++ +   GEL+ SLCY P+A  + + IIKARNLKAMDI G SDPYVKV LM   
Sbjct: 255 KDLKPCSDGSGSRGELLLSLCYNPSANSIIVNIIKARNLKAMDIGGTSDPYVKVWLMYKD 314

Query: 401 RRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGN 460
           +R++K+KT T +  LNP++NE+  FD+P E + +  + I VMD D++  N++IG   +  
Sbjct: 315 KRVEKKKTVTMKRNLNPIFNESFAFDIPTEKLRETTIIITVMDKDKLSRNDVIGKIYLSW 374

Query: 461 EAERLGRDHWSEMLSYPRKPIAHWHSL 487
           ++      HW +M++ PR+P+A WH L
Sbjct: 375 KSGPGEVKHWKDMIARPRQPVAQWHQL 401



 Score = 76.3 bits (186), Expect = 6e-14
 Identities = 43/104 (41%), Positives = 62/104 (59%), Gaps = 3/104 (2%)

Query: 352 DLGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTK 411
           +LG + FS+ Y      LT+ I+KA+ L A D +G SDP+VK+ L+ D +   K +T  K
Sbjct: 135 NLGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLLPDKKH--KLETKVK 192

Query: 412 RNTLNPVYNEAIVFD-VPPENIDQIHLSIAVMDYDRVGHNEIIG 454
           R  LNP +NE  +F+  P E + Q  L + V+DYDR   N+ IG
Sbjct: 193 RKNLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIG 236


>gi|24308219 synaptotagmin IV [Homo sapiens]
          Length = 425

 Score =  216 bits (550), Expect = 4e-56
 Identities = 127/345 (36%), Positives = 197/345 (57%), Gaps = 10/345 (2%)

Query: 154 VQRQVTEPTSSARHNSIRRQLNLSNPDFNIQQLQKQEQLTGIGRI----KPELYKQRSLD 209
           V+ +   P +S   +  +R LN + P  N++     +      ++    + E     SL 
Sbjct: 81  VKNKPAVPKNSLHLDLEKRDLNGNFPKTNLKPGSPSDLENATPKLFLEGEKESVSPESLK 140

Query: 210 NDDGRRSNSKA--CGKLNFILKYDCDLEQLIVKIHKAVNLPAKDF-SGTSDPYVKIYLLP 266
           +     S  K    G L F L+Y+ + +  +V I +A  LPA D  S TSDPY+K+ +LP
Sbjct: 141 SSTSLTSEEKQEKLGTLFFSLEYNFERKAFVVNIKEARGLPAMDEQSMTSDPYIKMTILP 200

Query: 267 DRKTKHQTKVHRKTLNPVFDEVFLF-PVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVD 325
           ++K K +T+V RKTL+P FDE F F  +PY  ++   LHF++  FDRFSR D+IG+V++ 
Sbjct: 201 EKKHKVKTRVLRKTLDPAFDETFTFYGIPYTQIQELALHFTILSFDRFSRDDIIGEVLIP 260

Query: 326 -HFLDLADFPRECILWKDIEYVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMDI 384
              ++L++  +  +  + I+     +   GEL+ SLCY  T   LT+ ++KAR+L   D+
Sbjct: 261 LSGIELSE-GKMLMNREIIKRNVRKSSGRGELLISLCYQSTTNTLTVVVLKARHLPKSDV 319

Query: 385 TGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDY 444
           +G SDPYVKV+L    +R+ K+KT  K+ T N V+NE  VFD+P E ++ I +   V+D 
Sbjct: 320 SGLSDPYVKVNLYHAKKRISKKKTHVKKCTPNAVFNELFVFDIPCEGLEDISVEFLVLDS 379

Query: 445 DRVGHNEIIGVCQVGNEAERLGRDHWSEMLSYPRKPIAHWHSLVE 489
           +R   NE+IG   +G  AE  G +HW E+  YPR+ IA WH L +
Sbjct: 380 ERGSRNEVIGQLVLGAAAEGTGGEHWKEICDYPRRQIAKWHVLCD 424


>gi|216548478 synaptotagmin XI [Homo sapiens]
          Length = 431

 Score =  207 bits (527), Expect = 2e-53
 Identities = 115/277 (41%), Positives = 171/277 (61%), Gaps = 14/277 (5%)

Query: 222 GKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGT-SDPYVKIYLLPDRKTKHQTKVHRKT 280
           G L F + Y+   + L+V I +A  LP  D     SDPY+K+ +LPD++ + +T+V RKT
Sbjct: 159 GSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLRKT 218

Query: 281 LNPVFDEVFLF-PVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVV-----DHFLDLADFP 334
           L+PVFDE F F  +PY+ L+   LHF V  FDRFSR D+IG+V+V     D         
Sbjct: 219 LDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGKVQLT 278

Query: 335 RECILWKDIEYVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMDITGAS-DPYVK 393
           R+ I+ ++I+      +  GEL  SL Y P A R+T+ ++KAR+L  MDITG S +PYVK
Sbjct: 279 RD-IIKRNIQKC----ISRGELQVSLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPYVK 333

Query: 394 VSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEII 453
           V++    +R+ K+KT  K+ TLNP++NE+ ++D+P + +  I +   V+D+DR   NE++
Sbjct: 334 VNVYYGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVV 393

Query: 454 GVCQVG-NEAERLGRDHWSEMLSYPRKPIAHWHSLVE 489
           G   +G +     G +HW E+   PRKP+A WHSL E
Sbjct: 394 GRLILGAHSVTASGAEHWREVCESPRKPVAKWHSLSE 430



 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 39/112 (34%), Positives = 61/112 (54%), Gaps = 4/112 (3%)

Query: 349 DNVDLGELMFSLCYLPTAGRLTITIIKARNLKAM-DITGASDPYVKVSLMCDGRRLKKRK 407
           ++V LG L FS+ Y      L +TI +A  L  M D T  SDPY+K++++ D R   + K
Sbjct: 154 EDVMLGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTILPDKRH--RVK 211

Query: 408 TSTKRNTLNPVYNEAIVF-DVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQV 458
           T   R TL+PV++E   F  +P   +  + L   V+ +DR   +++IG   V
Sbjct: 212 TRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMV 263


>gi|40068038 B/K protein [Homo sapiens]
          Length = 474

 Score =  186 bits (472), Expect = 4e-47
 Identities = 126/393 (32%), Positives = 201/393 (51%), Gaps = 46/393 (11%)

Query: 131 HTSPDIPLSTQTGIQENCAHGVRVQRQVTEPTSSARHNSIRRQLNL-----SNPDFNIQQ 185
           HT+ ++PL+ +T   +         R+ +  TS + ++  RR  +L     S+P  +I+ 
Sbjct: 75  HTASEVPLTPRTNSPDG--------RRSSSDTSKSTYSLTRRISSLESRRPSSPLIDIKP 126

Query: 186 LQ------KQEQLTG------------IGRIKPELYKQRSLDND-----DGRRSNSKACG 222
           ++      K+E +                + +P LY   S  +D     D    +    G
Sbjct: 127 IEFGVLSAKKEPIQPSVLRRTYNPDDYFRKFEPHLYSLDSNSDDVDSLTDEEILSKYQLG 186

Query: 223 KLNFILKYDCDLEQLIVKIHKAVNLP-------AKDFSGTSDPYVKIYLLPDRKTKHQTK 275
            L+F  +YD     L V++ +A +LP       ++     S+PYVKI LLPD+K   QT 
Sbjct: 187 MLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLLPDQKNSKQTG 246

Query: 276 VHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPR 335
           V RKT  PVF+E + F +P+ + + R L  +V DFD+FSRH +IG+V V   L   D  +
Sbjct: 247 VKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSVP--LCEVDLVK 304

Query: 336 ECILWKDIEYVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVS 395
               WK +   + + V+LGEL+ SL YLP+AGRL + +I+A+ L   D++  SDP+VK+ 
Sbjct: 305 GGHWWKALIPSSQNEVELGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGSDPFVKIQ 364

Query: 396 LMCDGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGV 455
           L+   + +K +KTS  R T++P YNE+  F VP E ++   L   V  ++    N+ IG 
Sbjct: 365 LVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSNDFIGR 424

Query: 456 CQVGNEAERLGR-DHWSEMLSYPRKPIAHWHSL 487
             +G  +      +HW  ML+  R  +  WHSL
Sbjct: 425 IVIGQYSSGPSETNHWRRMLNTHRTAVEQWHSL 457


>gi|31881675 synaptotagmin XV isoform a [Homo sapiens]
          Length = 421

 Score =  169 bits (428), Expect = 5e-42
 Identities = 108/299 (36%), Positives = 158/299 (52%), Gaps = 13/299 (4%)

Query: 195 IGRIKPELYKQRSLDNDDGRRSNSKAC-GKLNFILKYDCDLEQLIVKIHKAVNLPAKDFS 253
           +G I PELYK      D         C G+L F ++Y+ + E+L+V + KA +L A   S
Sbjct: 124 VGAINPELYK---FPEDKSETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQAP--S 178

Query: 254 GTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRF 313
            T  P VK+YLLPD +   Q+K  RKT NP FDE F+F V    +  R L FSVY  DR 
Sbjct: 179 ETCSPLVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQ 238

Query: 314 SRHDLIGQVVVDHFLDLADFPREC--ILWKDIEYVT-NDNVDLGELMFSLCYLPTAGRLT 370
            +H L+GQV+    L       +C  ++W+D+E  +     + G+L F L Y     RLT
Sbjct: 239 RKHQLLGQVLFP--LKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLT 296

Query: 371 ITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPE 430
           + +++A+ L+  +  G    +VKVSLM   + +K +KTS    ++NPVYNE   F     
Sbjct: 297 VVVLRAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADAT 356

Query: 431 NIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGR--DHWSEMLSYPRKPIAHWHSL 487
            +D   LS+ V+       ++ +G   VG      GR  +HW EMLS P++ +  WH+L
Sbjct: 357 ELDTASLSLTVVQNMEGDKSQQLGRVVVGPYMYTRGRELEHWDEMLSKPKELVKRWHAL 415


>gi|94536846 synaptotagmin VIII [Homo sapiens]
          Length = 401

 Score =  166 bits (419), Expect = 6e-41
 Identities = 97/284 (34%), Positives = 153/284 (53%), Gaps = 10/284 (3%)

Query: 205 QRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYL 264
           Q  +D  +    +++  G+L   L++D   +++ V + +A +L      GT DPY ++ +
Sbjct: 102 QPDVDGLESSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP---GGTVDPYARVSV 158

Query: 265 LPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVV 324
                 +H+TKVHR TL PVFDE   F +P  +L    L   +++F RFS H+ +G++ +
Sbjct: 159 STQAGHRHETKVHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRL 218

Query: 325 DHFLDLADFPRECILWKDI-EYVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMD 383
              L   D       W  +          +GEL FSL Y+P++GRLT+ +++AR L+   
Sbjct: 219 P--LGTVDLQHVLEHWYLLGPPAATQPEQVGELCFSLRYVPSSGRLTVVVLEARGLRP-- 274

Query: 384 ITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMD 443
             G ++PYVKV LM + R+ KKRKT+TK+ T  P +NEA  F VP   +  + L +AV D
Sbjct: 275 --GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWD 332

Query: 444 YDRVGHNEIIGVCQVGNEAERLGRDHWSEMLSYPRKPIAHWHSL 487
                  E +G   +G  A      HW++ML++ R+PIA  H L
Sbjct: 333 RSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARRPIAQRHPL 376


>gi|29366828 synaptotagmin XII [Homo sapiens]
          Length = 421

 Score =  155 bits (392), Expect = 8e-38
 Identities = 85/267 (31%), Positives = 148/267 (55%), Gaps = 3/267 (1%)

Query: 222 GKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTL 281
           G++   ++YD     L V + +  +L  ++ +     ++++ LLPD +    +++ R   
Sbjct: 154 GQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIVGISRIQRNAY 213

Query: 282 NPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECIL-W 340
           +  FDE F  P+    LE + L FSV+  D   R+   G  VV+  L + D P +    W
Sbjct: 214 SIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTG--VVELKLSVLDLPLQPFSGW 271

Query: 341 KDIEYVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDG 400
             ++        +GE++ SL YLPTA RLT+ ++KA+NL   +    +DP+VKV L+ DG
Sbjct: 272 LYLQDQNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDG 331

Query: 401 RRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGN 460
           R++ K+KT+ KR+  NPV+NEA++F VP   +  + L + V +    G  + +G   +G 
Sbjct: 332 RKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIGP 391

Query: 461 EAERLGRDHWSEMLSYPRKPIAHWHSL 487
            A  +G  HW++ML+  R+P++ WH++
Sbjct: 392 SASGMGTTHWNQMLATLRRPVSMWHAV 418



 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 39/107 (36%), Positives = 58/107 (54%), Gaps = 2/107 (1%)

Query: 220 ACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPD--RKTKHQTKVH 277
           A G++   L Y    E+L V + KA NL   +   T+DP+VK+YLL D  + +K +T V 
Sbjct: 283 AVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDGRKMSKKKTAVK 342

Query: 278 RKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVV 324
           R   NPVF+E  +F VP   L+   L  +V +     R D +G V++
Sbjct: 343 RDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVII 389


>gi|31881667 synaptotagmin XV isoform b [Homo sapiens]
          Length = 390

 Score =  146 bits (368), Expect = 5e-35
 Identities = 93/252 (36%), Positives = 135/252 (53%), Gaps = 11/252 (4%)

Query: 195 IGRIKPELYKQRSLDNDDGRRSNSKAC-GKLNFILKYDCDLEQLIVKIHKAVNLPAKDFS 253
           +G I PELYK      D         C G+L F ++Y+ + E+L+V + KA +L A   S
Sbjct: 124 VGAINPELYK---FPEDKSETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQAP--S 178

Query: 254 GTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRF 313
            T  P VK+YLLPD +   Q+K  RKT NP FDE F+F V    +  R L FSVY  DR 
Sbjct: 179 ETCSPLVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQ 238

Query: 314 SRHDLIGQVVVDHFLDLADFPREC--ILWKDIEYVT-NDNVDLGELMFSLCYLPTAGRLT 370
            +H L+GQV+    L       +C  ++W+D+E  +     + G+L F L Y     RLT
Sbjct: 239 RKHQLLGQVLFP--LKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLT 296

Query: 371 ITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPE 430
           + +++A+ L+  +  G    +VKVSLM   + +K +KTS    ++NPVYNE   F     
Sbjct: 297 VVVLRAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADAT 356

Query: 431 NIDQIHLSIAVM 442
            +D   LS+ V+
Sbjct: 357 ELDTASLSLTVV 368



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 39/102 (38%), Positives = 57/102 (55%), Gaps = 4/102 (3%)

Query: 353 LGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKR 412
           LG L FS+ Y   A RL + +IKA++L+A   T    P VK+ L+ D RR  + KT  KR
Sbjct: 148 LGRLWFSVEYEQEAERLLVGLIKAQHLQAPSET--CSPLVKLYLLPDERRFLQSKT--KR 203

Query: 413 NTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIG 454
            T NP ++E  +F V  + I Q  L  +V   DR   ++++G
Sbjct: 204 KTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLG 245


>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
          Length = 694

 Score =  144 bits (364), Expect = 1e-34
 Identities = 100/308 (32%), Positives = 152/308 (49%), Gaps = 33/308 (10%)

Query: 207 SLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLP 266
           S D+D+     +   G L F L YD D   L   I KA  L   D +G +DPYVK++LLP
Sbjct: 384 SYDSDE-----ATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLP 438

Query: 267 --DRKTKHQTKVHRKTLNPVFDEVFLFP-VPYNDLEARKLHFSVYDFDRFSRHDLIGQ-- 321
              +  K +TK  R T NP+++E  ++  +   D++ + L  SV D D+F  ++ IG+  
Sbjct: 439 GASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETR 498

Query: 322 ---------------VVVDHFLDL-----ADFPRECILWKD--IEYVTNDNVDLGELMFS 359
                          + ++  + +         R   L+++  +E V  D  + G+++ S
Sbjct: 499 FSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERV-GDIEERGKILVS 557

Query: 360 LCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVY 419
           L Y    G L + II+  +L AMD  G SDP+VK+ L  D  +  K KT  K+ TLNP +
Sbjct: 558 LMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEF 617

Query: 420 NEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGRDHWSEMLSYPRK 479
           NE   +D+   ++ +  L I+V DYD    N+ IG CQ+G  A+     HW E L    K
Sbjct: 618 NEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDK 677

Query: 480 PIAHWHSL 487
            I  WH L
Sbjct: 678 KIERWHQL 685


>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
          Length = 690

 Score =  144 bits (364), Expect = 1e-34
 Identities = 100/308 (32%), Positives = 152/308 (49%), Gaps = 33/308 (10%)

Query: 207 SLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLP 266
           S D+D+     +   G L F L YD D   L   I KA  L   D +G +DPYVK++LLP
Sbjct: 380 SYDSDE-----ATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLP 434

Query: 267 --DRKTKHQTKVHRKTLNPVFDEVFLFP-VPYNDLEARKLHFSVYDFDRFSRHDLIGQ-- 321
              +  K +TK  R T NP+++E  ++  +   D++ + L  SV D D+F  ++ IG+  
Sbjct: 435 GASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETR 494

Query: 322 ---------------VVVDHFLDL-----ADFPRECILWKD--IEYVTNDNVDLGELMFS 359
                          + ++  + +         R   L+++  +E V  D  + G+++ S
Sbjct: 495 FSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERV-GDIEERGKILVS 553

Query: 360 LCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVY 419
           L Y    G L + II+  +L AMD  G SDP+VK+ L  D  +  K KT  K+ TLNP +
Sbjct: 554 LMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEF 613

Query: 420 NEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGRDHWSEMLSYPRK 479
           NE   +D+   ++ +  L I+V DYD    N+ IG CQ+G  A+     HW E L    K
Sbjct: 614 NEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDK 673

Query: 480 PIAHWHSL 487
            I  WH L
Sbjct: 674 KIERWHQL 681


>gi|47078261 double C2-like domains, alpha [Homo sapiens]
          Length = 400

 Score =  140 bits (352), Expect = 3e-33
 Identities = 100/315 (31%), Positives = 147/315 (46%), Gaps = 37/315 (11%)

Query: 207 SLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLP 266
           S D+DD     + A G L F L YD     L   I +A  L   DF+G +DPYVK++LLP
Sbjct: 81  SYDSDD-----ATALGTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLLP 135

Query: 267 D--RKTKHQTKVHRKTLNPVFDEVFLFP-VPYNDLEARKLHFSVYDFDRFSRHDLIGQVV 323
              +  K +TK  R TLNPV++E   +  +  +D+  + L  +V D D+ S ++ IG++ 
Sbjct: 136 GACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGEIR 195

Query: 324 VD----------HF---------------LDLADFPRECILWKDIEYVTNDN---VDLGE 355
           V           HF               +  A     C L K++E          + G 
Sbjct: 196 VPLRRLKPSQKKHFNICLERQVPLASPSSMSAALRGISCYL-KELEQAEQGQGLLEERGR 254

Query: 356 LMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTL 415
           ++ SL Y      L + I++  +L AMD+ G SDPYVK  L  D  +  K KT  K+ TL
Sbjct: 255 ILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTL 314

Query: 416 NPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGRDHWSEMLS 475
           NP +NE   +++    +    L + V DYD    N+ IG   +G  A    R HWS+ L 
Sbjct: 315 NPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEARKHWSDCLQ 374

Query: 476 YPRKPIAHWHSLVEK 490
            P   +  WH+L  +
Sbjct: 375 QPDAALERWHTLTSE 389


>gi|24308233 synaptotagmin XIII [Homo sapiens]
          Length = 426

 Score =  139 bits (349), Expect = 8e-33
 Identities = 115/437 (26%), Positives = 197/437 (45%), Gaps = 30/437 (6%)

Query: 56  TLVVTACGLALFGVSLFVSWKLCWVPWRERGLPSGSKDNNQEPLNYMDTETNEQENSEDF 115
           TL      LAL GV+      LC     ++GL    +D + E        + +Q N +  
Sbjct: 13  TLGTATSILALCGVTC-----LCRHMHPKKGLLPRDQDPDLEKAKPSLLGSAQQFNVKKS 67

Query: 116 LDPPTPCPDSSMKISHTSPDIPLSTQTGIQENCAHGVRVQRQVTEPTSSARHNSIRRQLN 175
            +P  P   + +K        P  T   +     + +R   + T P S    N  R +  
Sbjct: 68  TEPVQP--RALLKFPDIYGPRPAVTAPEVINYADYSLRSTEEPTAPASPQPPNDSRLKRQ 125

Query: 176 LSNPDFNIQQLQKQEQLTGIGRIKPELYKQRSLDNDDGRRSNSKACGKLNFILKYDCDLE 235
           ++   F + Q    E +  +    PE            + ++     KL++ L YDC   
Sbjct: 126 VTEELFILPQNGVVEDVCVMETWNPE------------KAASWNQAPKLHYCLDYDCQKA 173

Query: 236 QLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDR-KTKHQTKVHRKTLNPVFDEVFLFPVP 294
           +L V   +AV     +  G  D YV+  +       + QT + ++ L+  ++E  + P+ 
Sbjct: 174 ELFVTRLEAVT---SNHDGGCDCYVQGSVANRTGSVEAQTALKKRQLHTTWEEGLVLPLA 230

Query: 295 YNDLEARKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWKDIEYVTND-NVDL 353
             +L    L  ++   DRFSRH + G++ +   LD    P     W +++    + +   
Sbjct: 231 EEELPTATLTLTLRTCDRFSRHSVAGELRLG--LDGTSVPLGAAQWGELKTSAKEPSAGA 288

Query: 354 GELMFSLCYLPTAGRLTITIIKARNL---KAMDITGASDPYVKVSLMCDGRRLKKRKTST 410
           GE++ S+ YLP A RL + +IKA+NL   ++ ++ G  D  VKV+L    R+LKK++T  
Sbjct: 289 GEVLLSISYLPAANRLLVVLIKAKNLHSNQSKELLG-KDVSVKVTLKHQARKLKKKQTKR 347

Query: 411 KRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGRDHW 470
            ++ +NPV+NE I+F++P + +    + + V+  D  G +  +G C +G       R HW
Sbjct: 348 AKHKINPVWNEMIMFELPDDLLQASSVELEVLGQDDSGQSCALGHCSLGLHTSGSERSHW 407

Query: 471 SEMLSYPRKPIAHWHSL 487
            EML  PR+ IA WH L
Sbjct: 408 EEMLKNPRRQIAMWHQL 424


>gi|6005997 double C2-like domains, beta [Homo sapiens]
          Length = 412

 Score =  136 bits (343), Expect = 4e-32
 Identities = 93/290 (32%), Positives = 140/290 (48%), Gaps = 8/290 (2%)

Query: 209 DNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLP-- 266
           D D     +  A G L+F L YD +   L   I KA  L   D +G +DPYVK++LLP  
Sbjct: 115 DADGYESDDCTALGTLDFSLLYDQENNALHCTITKAKGLKPMDHNGLADPYVKLHLLPGA 174

Query: 267 DRKTKHQTKVHRKTLNPVFDEVFLF-PVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVD 325
            +  K +TK  R TLNP ++E   +  +   D+  + L  SV D D+F  ++ IG+  V 
Sbjct: 175 SKANKLRTKTLRNTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGETRVP 234

Query: 326 HFLDLADFPR--ECILWKDIEYVTNDNVDL---GELMFSLCYLPTAGRLTITIIKARNLK 380
                 +  +     L K +     ++  L   G ++ SL Y      L + I++  +L 
Sbjct: 235 LKKLKPNHTKTFNICLEKQLPVDKTEDKSLEERGRILISLKYSSQKQGLLVGIVRCAHLA 294

Query: 381 AMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIA 440
           AMD  G SDPYVK  L  D  +  K KT+ K+ TLNP +NE   +++   ++ +  L + 
Sbjct: 295 AMDANGYSDPYVKTYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYEIKHGDLAKKSLEVT 354

Query: 441 VMDYDRVGHNEIIGVCQVGNEAERLGRDHWSEMLSYPRKPIAHWHSLVEK 490
           V DYD    N+ IG   +G  A+     HW + L    K I  WH+L  +
Sbjct: 355 VWDYDIGKSNDFIGGVVLGIHAKGERLKHWFDCLKNKDKRIERWHTLTSE 404



 Score = 89.0 bits (219), Expect = 9e-18
 Identities = 49/125 (39%), Positives = 74/125 (59%), Gaps = 4/125 (3%)

Query: 202 LYKQRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVK 261
           L KQ  +D  + +    +  G++   LKY    + L+V I +  +L A D +G SDPYVK
Sbjct: 250 LEKQLPVDKTEDKSLEER--GRILISLKYSSQKQGLLVGIVRCAHLAAMDANGYSDPYVK 307

Query: 262 IYLLP--DRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLI 319
            YL P  D+K+KH+T V +KTLNP F+E F + + + DL  + L  +V+D+D    +D I
Sbjct: 308 TYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYEIKHGDLAKKSLEVTVWDYDIGKSNDFI 367

Query: 320 GQVVV 324
           G VV+
Sbjct: 368 GGVVL 372


>gi|193804862 synaptotagmin-like 4 [Homo sapiens]
          Length = 671

 Score =  117 bits (294), Expect = 2e-26
 Identities = 87/284 (30%), Positives = 135/284 (47%), Gaps = 38/284 (13%)

Query: 207 SLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLP-AKDFSGTSDPYVKIYLL 265
           S+ ++ G   N    G++ F LKY+   + L+V + +   L  A +    S+PYVK YLL
Sbjct: 343 SIYSEAGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLL 402

Query: 266 PD--RKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVV 323
           PD  R+ K +T + R T+NP++DE   + +P + L  R L FSV+   RF R+  +G+  
Sbjct: 403 PDKSRQGKRKTSIKRDTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAE 462

Query: 324 V-----------DHFLDLADFPRECILWKDIEYVTNDNVDLGELMFSLCYLPTA------ 366
           +           DH L L             E  T      GEL+ SL Y+P +      
Sbjct: 463 IQMDSWKLDKKLDHCLPLHG-------KISAESPTGLPSHKGELVVSLKYIPASKTPVGG 515

Query: 367 ----------GRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLN 416
                     G L + I +A+NL A    G SD +VK  L+    +  KRKT   + TLN
Sbjct: 516 DRKKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLN 575

Query: 417 PVYNEAIVFD-VPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVG 459
           P YN   V++ V  E++  + L + V D + +  N+ +G  ++G
Sbjct: 576 PHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLG 619



 Score = 66.6 bits (161), Expect = 5e-11
 Identities = 39/119 (32%), Positives = 63/119 (52%), Gaps = 3/119 (2%)

Query: 354 GELMFSLCYLPTAGRLTITIIKARNLKAMD-ITGASDPYVKVSLMCDGRRLKKRKTSTKR 412
           G + FSL Y      L + + +   L   D     S+PYVK  L+ D  R  KRKTS KR
Sbjct: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417

Query: 413 NTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGR--DH 469
           +T+NP+Y+E + +++P   + Q  L  +V  + R G N  +G  ++  ++ +L +  DH
Sbjct: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDH 476


>gi|193804860 synaptotagmin-like 4 [Homo sapiens]
          Length = 671

 Score =  117 bits (294), Expect = 2e-26
 Identities = 87/284 (30%), Positives = 135/284 (47%), Gaps = 38/284 (13%)

Query: 207 SLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLP-AKDFSGTSDPYVKIYLL 265
           S+ ++ G   N    G++ F LKY+   + L+V + +   L  A +    S+PYVK YLL
Sbjct: 343 SIYSEAGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLL 402

Query: 266 PD--RKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVV 323
           PD  R+ K +T + R T+NP++DE   + +P + L  R L FSV+   RF R+  +G+  
Sbjct: 403 PDKSRQGKRKTSIKRDTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAE 462

Query: 324 V-----------DHFLDLADFPRECILWKDIEYVTNDNVDLGELMFSLCYLPTA------ 366
           +           DH L L             E  T      GEL+ SL Y+P +      
Sbjct: 463 IQMDSWKLDKKLDHCLPLHG-------KISAESPTGLPSHKGELVVSLKYIPASKTPVGG 515

Query: 367 ----------GRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLN 416
                     G L + I +A+NL A    G SD +VK  L+    +  KRKT   + TLN
Sbjct: 516 DRKKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLN 575

Query: 417 PVYNEAIVFD-VPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVG 459
           P YN   V++ V  E++  + L + V D + +  N+ +G  ++G
Sbjct: 576 PHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLG 619



 Score = 66.6 bits (161), Expect = 5e-11
 Identities = 39/119 (32%), Positives = 63/119 (52%), Gaps = 3/119 (2%)

Query: 354 GELMFSLCYLPTAGRLTITIIKARNLKAMD-ITGASDPYVKVSLMCDGRRLKKRKTSTKR 412
           G + FSL Y      L + + +   L   D     S+PYVK  L+ D  R  KRKTS KR
Sbjct: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417

Query: 413 NTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGR--DH 469
           +T+NP+Y+E + +++P   + Q  L  +V  + R G N  +G  ++  ++ +L +  DH
Sbjct: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDH 476


>gi|123173752 synaptotagmin XIV-like [Homo sapiens]
          Length = 645

 Score =  115 bits (288), Expect = 9e-26
 Identities = 105/391 (26%), Positives = 166/391 (42%), Gaps = 29/391 (7%)

Query: 126 SMKISHTSPD-IPLSTQTGIQENCAHGVRVQRQVTEPTSSARHNSIRRQLNLSNPDFNIQ 184
           S  +S+   D IP  +Q+  +   A       Q +    S R  S    L +    FN +
Sbjct: 256 SENLSYGEDDHIPAHSQSPCERGDAKHHGTSHQESSVVQSLRRQSTEGSLEMETA-FNSR 314

Query: 185 QLQKQEQLTGIGRIKPELYKQRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKA 244
             +            PE   + +L    G       CG L+ I +Y    ++L V I +A
Sbjct: 315 GFEDSYATDSSSMWSPEEQDRTNLQVPSGVSEPISKCGDLDVIFEYRAASQKLTVTIVRA 374

Query: 245 VNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFP-VPYNDLEARKL 303
             LP KD SG +   V + LLP +K + +T + R   NPVF E   F  +   D+ A  +
Sbjct: 375 QGLPDKDRSGVNSWQVHVVLLPGKKHRGRTNIQRGP-NPVFREKVTFAKLEPRDVAACAV 433

Query: 304 HFSVYDFDRFSRHDLIGQVV--VDHF-------LDLADFPRE------------CILWKD 342
            F +Y   + +R  ++G+ +  + H        + L   PR              +   D
Sbjct: 434 RFRLYAARKMTRERMMGEKLFYLSHLHPEGEMKVTLVLEPRSNISSGGSPLSPSAVSHSD 493

Query: 343 IEYVTNDNVDLG--ELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCD- 399
               T      G  EL+  L Y  T GRL++ +IK  + + + +  A D Y K+ L+   
Sbjct: 494 STSSTQSLSHGGAPELLVGLSYNATTGRLSVEMIKGSHFRNLAVNRAPDTYGKLFLLNSV 553

Query: 400 GRRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVG 459
           G+ + + KTS +R   NPVY E  VF V    +  + L I+V +   +   E+IG   +G
Sbjct: 554 GQEMSRCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLMISVYNRRTMKRKEMIGWIALG 613

Query: 460 -NEAERLGRDHWSEMLSYPRKPIAHWHSLVE 489
            N +    +DHW EM     + I  WH+L+E
Sbjct: 614 QNSSGEEEQDHWEEMKETKGQQICRWHTLLE 644


>gi|239744413 PREDICTED: hypothetical protein LOC390213 [Homo
           sapiens]
          Length = 431

 Score =  108 bits (269), Expect = 1e-23
 Identities = 86/297 (28%), Positives = 133/297 (44%), Gaps = 19/297 (6%)

Query: 212 DGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTK 271
           +G   +S A G L F L ++ D   L    H+A  L     SG++D YVK  LLP     
Sbjct: 130 EGDSDDSTALGTLEFTLLFEADNSALHCTAHRAKGLKPLA-SGSADAYVKANLLPGASKA 188

Query: 272 HQTKVH--RKTLNPVFDEVFLFP-VPYNDLEARKLHFSVYDFD----------RFSRHDL 318
            Q + H  R T  PV++E   +      D E + L   +              R  +   
Sbjct: 189 SQLRTHTVRGTRVPVWEETLTYHGFTRQDAECKTLRSDLGGHQAVCVRGPMVQRQWQAPS 248

Query: 319 IGQVVVDHFLDLADFPRE---CILWKDIEYVTNDNV--DLGELMFSLCYLPTAGRLTITI 373
           +G++ V     + +  R    C+  + +E V  +    + G ++ SLCY    G L + +
Sbjct: 249 LGELRVPLRKLVPNRARSFDICLEKRRLEEVETEVAWEECGHVLLSLCYSSQQGGLLVGV 308

Query: 374 IKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPENID 433
           ++  +L  MD  G SDP+V++ L  +  +  K KTS  R TLNP +NE   +  P E + 
Sbjct: 309 LRCAHLAPMDANGYSDPFVRLFLHPNAGKKSKFKTSVHRKTLNPEFNEEFFYSGPREELA 368

Query: 434 QIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGRDHWSEMLSYPRKPIAHWHSLVEK 490
           Q  L ++V DYD    ++ IG  Q+G+ A      HW E L +    +  WH L  K
Sbjct: 369 QKTLLVSVWDYDLGTADDFIGGVQLGSHASGERLRHWLECLGHSDHRLKLWHPLDSK 425



 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 55/182 (30%), Positives = 88/182 (48%), Gaps = 21/182 (11%)

Query: 143 GIQENCAHGVRVQRQVTEPTSSARHNSIRRQLNLSNPDFNIQQLQKQEQLTGIGRIKPEL 202
           G Q  C  G  VQRQ   P+       +R+ +      F+I  L+K+     +  ++ E+
Sbjct: 229 GHQAVCVRGPMVQRQWQAPSLGELRVPLRKLVPNRARSFDIC-LEKRR----LEEVETEV 283

Query: 203 YKQRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKI 262
             +               CG +   L Y      L+V + +  +L   D +G SDP+V++
Sbjct: 284 AWEE--------------CGHVLLSLCYSSQQGGLLVGVLRCAHLAPMDANGYSDPFVRL 329

Query: 263 YLLPD--RKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIG 320
           +L P+  +K+K +T VHRKTLNP F+E F +  P  +L  + L  SV+D+D  +  D IG
Sbjct: 330 FLHPNAGKKSKFKTSVHRKTLNPEFNEEFFYSGPREELAQKTLLVSVWDYDLGTADDFIG 389

Query: 321 QV 322
            V
Sbjct: 390 GV 391


>gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens]
          Length = 935

 Score =  102 bits (255), Expect = 6e-22
 Identities = 103/432 (23%), Positives = 198/432 (45%), Gaps = 53/432 (12%)

Query: 85  RGLPSGS-KDNNQEPLNYMDTETNEQE---NSEDFLDPPTPCPDSSM----KISHTSPDI 136
           R +PS S +D + +  N    +   +E   ++ED    PT  PD+      K+   S  +
Sbjct: 506 RKMPSKSLEDISSDSSNQAKVDNQPEELVRSAEDVSTVPTQ-PDNPFSHPDKLKRMSKSV 564

Query: 137 PLSTQTGIQENCAHGVRVQRQVTEPTSSARHNSIRRQLNLSNPDFNIQQLQKQEQLTGIG 196
           P   Q    +               T +A  +S +   +  +P  ++  L     +T + 
Sbjct: 565 PAFLQDESDDR-------------ETDTASESSYQLSRHKKSPS-SLTNLSSSSGMTSLS 610

Query: 197 RIKPELYKQRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGT- 255
            +   +    S     G   N +  G + F ++Y   L++L V + +  +L A D     
Sbjct: 611 SVSGSVMSVYS-----GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQR 665

Query: 256 SDPYVKIYLLPDRKT--KHQTKVHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRF 313
           SDPYVK YLLPD+    K +T V +KTLNPV++E+  + +    L+ +KL+ S++  D F
Sbjct: 666 SDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTF 725

Query: 314 SRHDLIGQVVVD-HFLDLADFPRECILWKDIEY----VTNDNVDLGELMFSLCY------ 362
            R+  +G+V +D    D  +   + + W  ++     V  +  + GE+  +L Y      
Sbjct: 726 KRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVP 785

Query: 363 ---LPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVY 419
              LPT G + I + +  +L  +  +  +  +VK +++ D  R  ++KT     T NP++
Sbjct: 786 GKKLPTTGEVHIWVKECLDLPLLRGSHLNS-FVKCTILPDTSRKSRQKTRAVGKTTNPIF 844

Query: 420 NEAIVFD-VPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGRDHWSEM--LSY 476
           N  +V+D   PE++ +  + + V D+ ++  N+ +G  ++G      G+ + +E+  +  
Sbjct: 845 NHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGFGT---GKSYGTEVDWMDS 900

Query: 477 PRKPIAHWHSLV 488
             + +A W  +V
Sbjct: 901 TSEEVALWEKMV 912


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,772,346
Number of Sequences: 37866
Number of extensions: 905759
Number of successful extensions: 3225
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 116
Number of HSP's successfully gapped in prelim test: 72
Number of HSP's that attempted gapping in prelim test: 2395
Number of HSP's gapped (non-prelim): 524
length of query: 491
length of database: 18,247,518
effective HSP length: 106
effective length of query: 385
effective length of database: 14,233,722
effective search space: 5479982970
effective search space used: 5479982970
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.