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Search of human proteins with 26892295
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|26892295 methylmalonic aciduria type A precursor [Homo
sapiens]
(418 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|26892295 methylmalonic aciduria type A precursor [Homo sapiens] 835 0.0
gi|30260188 Golgi autoantigen, golgin subfamily a, 5 [Homo sapiens] 36 0.057
gi|54792740 transmembrane and coiled-coil domain family 2 [Homo ... 34 0.22
gi|88759337 ATP binding domain 1 family, member B [Homo sapiens] 33 0.37
gi|14249342 internexin neuronal intermediate filament protein, a... 32 1.1
gi|21396489 mitochondrial lon peptidase 1 [Homo sapiens] 30 3.1
gi|215820660 ATP-binding cassette, subfamily G, member 4 [Homo s... 30 4.1
gi|20143975 ATP-binding cassette, subfamily G, member 4 [Homo sa... 30 4.1
gi|42718017 retinoblastoma binding protein 8 isoform b [Homo sap... 30 5.3
gi|42718015 retinoblastoma binding protein 8 isoform a [Homo sap... 30 5.3
gi|4506441 retinoblastoma binding protein 8 isoform a [Homo sapi... 30 5.3
gi|91992162 mutL homolog 3 isoform 1 [Homo sapiens] 30 5.3
gi|91992160 mutL homolog 3 isoform 2 [Homo sapiens] 30 5.3
gi|156564401 vesicle-fusing ATPase [Homo sapiens] 29 9.1
gi|113426932 PREDICTED: similar to N-ethylmaleimide-sensitive fa... 29 9.1
gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens] 29 9.1
gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens] 29 9.1
gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens] 29 9.1
>gi|26892295 methylmalonic aciduria type A precursor [Homo sapiens]
Length = 418
Score = 835 bits (2156), Expect = 0.0
Identities = 418/418 (100%), Positives = 418/418 (100%)
Query: 1 MPMLLPHPHQHFLKGLLRAPFRCYHFIFHSSTHLGSGIPCAQPFNSLGLHCTKWMLLSDG 60
MPMLLPHPHQHFLKGLLRAPFRCYHFIFHSSTHLGSGIPCAQPFNSLGLHCTKWMLLSDG
Sbjct: 1 MPMLLPHPHQHFLKGLLRAPFRCYHFIFHSSTHLGSGIPCAQPFNSLGLHCTKWMLLSDG 60
Query: 61 LKRKLCVQTTLKDHTEGLSDKEQRFVDKLYTGLIQGQRACLAEAITLVESTHSRKKELAQ 120
LKRKLCVQTTLKDHTEGLSDKEQRFVDKLYTGLIQGQRACLAEAITLVESTHSRKKELAQ
Sbjct: 61 LKRKLCVQTTLKDHTEGLSDKEQRFVDKLYTGLIQGQRACLAEAITLVESTHSRKKELAQ 120
Query: 121 VLLQKVLLYHREQEQSNKGKPLAFRVGLSGPPGAGKSTFIEYFGKMLTERGHKLSVLAVD 180
VLLQKVLLYHREQEQSNKGKPLAFRVGLSGPPGAGKSTFIEYFGKMLTERGHKLSVLAVD
Sbjct: 121 VLLQKVLLYHREQEQSNKGKPLAFRVGLSGPPGAGKSTFIEYFGKMLTERGHKLSVLAVD 180
Query: 181 PSSCTSGGSLLGDKTRMTELSRDMNAYIRPSPTRGTLGGVTRTTNEAILLCEGAGYDIIL 240
PSSCTSGGSLLGDKTRMTELSRDMNAYIRPSPTRGTLGGVTRTTNEAILLCEGAGYDIIL
Sbjct: 181 PSSCTSGGSLLGDKTRMTELSRDMNAYIRPSPTRGTLGGVTRTTNEAILLCEGAGYDIIL 240
Query: 241 IETVGVGQSEFAVADMVDMFVLLLPPAGGDELQGIKRGIIEMADLVAVTKSDGDLIVPAR 300
IETVGVGQSEFAVADMVDMFVLLLPPAGGDELQGIKRGIIEMADLVAVTKSDGDLIVPAR
Sbjct: 241 IETVGVGQSEFAVADMVDMFVLLLPPAGGDELQGIKRGIIEMADLVAVTKSDGDLIVPAR 300
Query: 301 RIQAEYVSALKLLRKRSQVWKPKVIRISARSGEGISEMWDKMKDFQDLMLASGELTAKRR 360
RIQAEYVSALKLLRKRSQVWKPKVIRISARSGEGISEMWDKMKDFQDLMLASGELTAKRR
Sbjct: 301 RIQAEYVSALKLLRKRSQVWKPKVIRISARSGEGISEMWDKMKDFQDLMLASGELTAKRR 360
Query: 361 KQQKVWMWNLIQESVLEHFRTHPTVREQIPLLEQKVLIGALSPGLAADFLLKAFKSRD 418
KQQKVWMWNLIQESVLEHFRTHPTVREQIPLLEQKVLIGALSPGLAADFLLKAFKSRD
Sbjct: 361 KQQKVWMWNLIQESVLEHFRTHPTVREQIPLLEQKVLIGALSPGLAADFLLKAFKSRD 418
>gi|30260188 Golgi autoantigen, golgin subfamily a, 5 [Homo sapiens]
Length = 731
Score = 36.2 bits (82), Expect = 0.057
Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 2/69 (2%)
Query: 70 TLKDHTEGLSDKEQRFVDKLYTGLIQGQRACLAEAITLVESTHSRKKELAQVLLQKVLLY 129
TLK E + F +L ++ +R LAEAITL E +S +K+ L Q+V LY
Sbjct: 360 TLKREQESYKQMQSEFAARL--NKVEMERQNLAEAITLAERKYSDEKKRVDELQQQVKLY 417
Query: 130 HREQEQSNK 138
E S +
Sbjct: 418 KLNLESSKQ 426
>gi|54792740 transmembrane and coiled-coil domain family 2 [Homo
sapiens]
Length = 709
Score = 34.3 bits (77), Expect = 0.22
Identities = 35/154 (22%), Positives = 64/154 (41%), Gaps = 24/154 (15%)
Query: 132 EQEQSNKGKPLAFRVGLSGPPGAGKSTFIEYFGKMLTERGHKLSVLAVDPSSCTSGGSLL 191
E+E+S + +++ + L P + F ++L + + S+ +SGG
Sbjct: 122 EKERSPEMHRVSYAMSLHDLPARPTA-----FNRVLQQIRSRPSIKRGASLHSSSGGGSS 176
Query: 192 GDKTRMTELS-----RDMNAYIRPSPTRGTLGGV----------TRTTNEAILLCEGAGY 236
G +R T+ S R +R +P +L + + TT+ A+LL +G+
Sbjct: 177 GSSSRRTKSSSLEPQRGSPHLLRKAPQDSSLAAILHQHQCRPRSSSTTDTALLLADGSNV 236
Query: 237 DIILIETVGVGQSEFAVADMVDMFVLLLPPAGGD 270
++ E G+G D D+ L LP GD
Sbjct: 237 YLLAEEAEGIGDK----VDKGDLVALSLPAGHGD 266
>gi|88759337 ATP binding domain 1 family, member B [Homo sapiens]
Length = 310
Score = 33.5 bits (75), Expect = 0.37
Identities = 14/41 (34%), Positives = 26/41 (63%)
Query: 143 AFRVGLSGPPGAGKSTFIEYFGKMLTERGHKLSVLAVDPSS 183
AF + GPPG+GK+T+ + L G +++V+ +DP++
Sbjct: 9 AFGQAVIGPPGSGKTTYCLGMSEFLRALGRRVAVVNLDPAN 49
>gi|14249342 internexin neuronal intermediate filament protein,
alpha [Homo sapiens]
Length = 499
Score = 32.0 bits (71), Expect = 1.1
Identities = 26/122 (21%), Positives = 59/122 (48%), Gaps = 7/122 (5%)
Query: 30 SSTHLGSGIPCAQPFNSLGLHCTKWMLLSDGLKRKLCVQTTLKDHTEGLSDKEQRFVDKL 89
S++ LG G+ +P S GL ++ ++ K ++T K+ +GL+D+ F++K+
Sbjct: 56 SASSLGLGLAYRRPPASDGLDLSQAAARTNEYK---IIRTNEKEQLQGLNDRFAVFIEKV 112
Query: 90 YTGLIQGQRACLAEAITLVESTHSRKKELAQVLLQKV--LLYHREQEQSNKGKPLAFRVG 147
+ ++ Q L + + H+ + ++ +++ L E+ S + + L R G
Sbjct: 113 HQ--LETQNRALEAELAALRQRHAEPSRVGELFQRELRDLRAQLEEASSARSQALLERDG 170
Query: 148 LS 149
L+
Sbjct: 171 LA 172
>gi|21396489 mitochondrial lon peptidase 1 [Homo sapiens]
Length = 959
Score = 30.4 bits (67), Expect = 3.1
Identities = 35/150 (23%), Positives = 58/150 (38%), Gaps = 26/150 (17%)
Query: 92 GLIQGQRACLAEAITLVESTHSRKKELAQVLLQKVLLYHREQEQSNKGKPLAFRVGLSGP 151
G + LA A ++E H +++ + +L+ + + + S +GK L F GP
Sbjct: 471 GKYSNENLDLARAQAVLEEDHYGMEDVKKRILEFIAV--SQLRGSTQGKILCFY----GP 524
Query: 152 PGAGKSTFIEYFGKMLTERGHKLSVLAVDPSSCTSGGSLLGDKTRMTELSRDMNAYIRPS 211
PG GK++ + L + SV G T + E+ Y+
Sbjct: 525 PGVGKTSIARSIARALNREYFRFSV---------------GGMTDVAEIKGHRRTYVGAM 569
Query: 212 PTR-GTLGGVTRTTNEAILLCE----GAGY 236
P + T+T N IL+ E G GY
Sbjct: 570 PGKIIQCLKKTKTENPLILIDEVDKIGRGY 599
>gi|215820660 ATP-binding cassette, subfamily G, member 4 [Homo
sapiens]
Length = 646
Score = 30.0 bits (66), Expect = 4.1
Identities = 20/63 (31%), Positives = 28/63 (44%), Gaps = 14/63 (22%)
Query: 146 VGLSGPPGAGKSTFIEYFGKMLTERGHKLSVLAVDPSSCTSGGSLLGDKTRMTELSRDMN 205
+G+ GP GAGKSTF +++LA S G L+ + R R M+
Sbjct: 98 IGIMGPSGAGKSTF--------------MNILAGYRESGMKGQILVNGRPRELRTFRKMS 143
Query: 206 AYI 208
YI
Sbjct: 144 CYI 146
>gi|20143975 ATP-binding cassette, subfamily G, member 4 [Homo
sapiens]
Length = 646
Score = 30.0 bits (66), Expect = 4.1
Identities = 20/63 (31%), Positives = 28/63 (44%), Gaps = 14/63 (22%)
Query: 146 VGLSGPPGAGKSTFIEYFGKMLTERGHKLSVLAVDPSSCTSGGSLLGDKTRMTELSRDMN 205
+G+ GP GAGKSTF +++LA S G L+ + R R M+
Sbjct: 98 IGIMGPSGAGKSTF--------------MNILAGYRESGMKGQILVNGRPRELRTFRKMS 143
Query: 206 AYI 208
YI
Sbjct: 144 CYI 146
>gi|42718017 retinoblastoma binding protein 8 isoform b [Homo
sapiens]
Length = 867
Score = 29.6 bits (65), Expect = 5.3
Identities = 21/80 (26%), Positives = 39/80 (48%), Gaps = 6/80 (7%)
Query: 328 SARSGEGISEMWDKMKDFQDLMLASGELTAKRRKQQKVWMWNLIQESVLEHFRTHPTVRE 387
SA + ++W K+K+ D + ++ + KQ+++ L + + E F + +RE
Sbjct: 13 SADTSSDFKDLWTKLKECHDREVQGLQVKVTKLKQERI----LDAQRLEEFFTKNQQLRE 68
Query: 388 QIPLLEQ--KVLIGALSPGL 405
Q +L + KVL L GL
Sbjct: 69 QQKVLHETIKVLEDRLRAGL 88
>gi|42718015 retinoblastoma binding protein 8 isoform a [Homo
sapiens]
Length = 897
Score = 29.6 bits (65), Expect = 5.3
Identities = 21/80 (26%), Positives = 39/80 (48%), Gaps = 6/80 (7%)
Query: 328 SARSGEGISEMWDKMKDFQDLMLASGELTAKRRKQQKVWMWNLIQESVLEHFRTHPTVRE 387
SA + ++W K+K+ D + ++ + KQ+++ L + + E F + +RE
Sbjct: 13 SADTSSDFKDLWTKLKECHDREVQGLQVKVTKLKQERI----LDAQRLEEFFTKNQQLRE 68
Query: 388 QIPLLEQ--KVLIGALSPGL 405
Q +L + KVL L GL
Sbjct: 69 QQKVLHETIKVLEDRLRAGL 88
>gi|4506441 retinoblastoma binding protein 8 isoform a [Homo
sapiens]
Length = 897
Score = 29.6 bits (65), Expect = 5.3
Identities = 21/80 (26%), Positives = 39/80 (48%), Gaps = 6/80 (7%)
Query: 328 SARSGEGISEMWDKMKDFQDLMLASGELTAKRRKQQKVWMWNLIQESVLEHFRTHPTVRE 387
SA + ++W K+K+ D + ++ + KQ+++ L + + E F + +RE
Sbjct: 13 SADTSSDFKDLWTKLKECHDREVQGLQVKVTKLKQERI----LDAQRLEEFFTKNQQLRE 68
Query: 388 QIPLLEQ--KVLIGALSPGL 405
Q +L + KVL L GL
Sbjct: 69 QQKVLHETIKVLEDRLRAGL 88
>gi|91992162 mutL homolog 3 isoform 1 [Homo sapiens]
Length = 1453
Score = 29.6 bits (65), Expect = 5.3
Identities = 15/36 (41%), Positives = 19/36 (52%), Gaps = 2/36 (5%)
Query: 193 DKTRMTELSRDMNAYIRPSPTRG--TLGGVTRTTNE 226
+KT+ TE Y+RP PTR T G TR + E
Sbjct: 616 EKTKSTETEHSFKNYVRPGPTRAQETFGNRTRHSVE 651
>gi|91992160 mutL homolog 3 isoform 2 [Homo sapiens]
Length = 1429
Score = 29.6 bits (65), Expect = 5.3
Identities = 15/36 (41%), Positives = 19/36 (52%), Gaps = 2/36 (5%)
Query: 193 DKTRMTELSRDMNAYIRPSPTRG--TLGGVTRTTNE 226
+KT+ TE Y+RP PTR T G TR + E
Sbjct: 616 EKTKSTETEHSFKNYVRPGPTRAQETFGNRTRHSVE 651
>gi|156564401 vesicle-fusing ATPase [Homo sapiens]
Length = 744
Score = 28.9 bits (63), Expect = 9.1
Identities = 13/27 (48%), Positives = 15/27 (55%)
Query: 148 LSGPPGAGKSTFIEYFGKMLTERGHKL 174
L GPPG GK+ GKML R K+
Sbjct: 258 LYGPPGCGKTLLARQIGKMLNAREPKV 284
>gi|113426932 PREDICTED: similar to N-ethylmaleimide-sensitive
factor [Homo sapiens]
Length = 563
Score = 28.9 bits (63), Expect = 9.1
Identities = 13/27 (48%), Positives = 15/27 (55%)
Query: 148 LSGPPGAGKSTFIEYFGKMLTERGHKL 174
L GPPG GK+ GKML R K+
Sbjct: 331 LYGPPGCGKTLLARQIGKMLNAREPKV 357
>gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens]
Length = 786
Score = 28.9 bits (63), Expect = 9.1
Identities = 45/205 (21%), Positives = 78/205 (38%), Gaps = 41/205 (20%)
Query: 69 TTLKDHTEGLSDKEQRFVDKLYTGLIQGQRACLAEAITLVESTHSRKKELAQVLLQKVLL 128
T L + + L K+Q ++++Y I+G + A+ + +H+ KEL +L
Sbjct: 360 TLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPIL--FAF 417
Query: 129 YHREQEQSNKGKPLAFRVGLSGPPGAGKSTFIEYFGKMLTERGHKLSVLAVDPSSCTSGG 188
H E G+ + + GP + + F K ++RG + T G
Sbjct: 418 SHLESSDGEAGRDPPAKDVMPGP----RQELLCAFWKSDSDRGGHWA---------TEGC 464
Query: 189 SLLGDKTRMTELSRDMNAYIRPSPTRGTLGGVTRTTNEAILLCEGAGYDI-----ILIET 243
+LG K T + ++ AIL+ A YD+ LI
Sbjct: 465 QVLGSKNGSTTCQ------------------CSHLSSFAILM---AHYDVEDWKLTLITR 503
Query: 244 VGVGQSEFAVADMVDMFVLLLPPAG 268
VG+ S F + + F+L+ P G
Sbjct: 504 VGLALSLFCLLLCILTFLLVRPIQG 528
>gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens]
Length = 742
Score = 28.9 bits (63), Expect = 9.1
Identities = 45/205 (21%), Positives = 78/205 (38%), Gaps = 41/205 (20%)
Query: 69 TTLKDHTEGLSDKEQRFVDKLYTGLIQGQRACLAEAITLVESTHSRKKELAQVLLQKVLL 128
T L + + L K+Q ++++Y I+G + A+ + +H+ KEL +L
Sbjct: 316 TLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPIL--FAF 373
Query: 129 YHREQEQSNKGKPLAFRVGLSGPPGAGKSTFIEYFGKMLTERGHKLSVLAVDPSSCTSGG 188
H E G+ + + GP + + F K ++RG + T G
Sbjct: 374 SHLESSDGEAGRDPPAKDVMPGP----RQELLCAFWKSDSDRGGHWA---------TEGC 420
Query: 189 SLLGDKTRMTELSRDMNAYIRPSPTRGTLGGVTRTTNEAILLCEGAGYDI-----ILIET 243
+LG K T + ++ AIL+ A YD+ LI
Sbjct: 421 QVLGSKNGSTTCQ------------------CSHLSSFAILM---AHYDVEDWKLTLITR 459
Query: 244 VGVGQSEFAVADMVDMFVLLLPPAG 268
VG+ S F + + F+L+ P G
Sbjct: 460 VGLALSLFCLLLCILTFLLVRPIQG 484
>gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens]
Length = 835
Score = 28.9 bits (63), Expect = 9.1
Identities = 45/205 (21%), Positives = 78/205 (38%), Gaps = 41/205 (20%)
Query: 69 TTLKDHTEGLSDKEQRFVDKLYTGLIQGQRACLAEAITLVESTHSRKKELAQVLLQKVLL 128
T L + + L K+Q ++++Y I+G + A+ + +H+ KEL +L
Sbjct: 409 TLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPIL--FAF 466
Query: 129 YHREQEQSNKGKPLAFRVGLSGPPGAGKSTFIEYFGKMLTERGHKLSVLAVDPSSCTSGG 188
H E G+ + + GP + + F K ++RG + T G
Sbjct: 467 SHLESSDGEAGRDPPAKDVMPGP----RQELLCAFWKSDSDRGGHWA---------TEGC 513
Query: 189 SLLGDKTRMTELSRDMNAYIRPSPTRGTLGGVTRTTNEAILLCEGAGYDI-----ILIET 243
+LG K T + ++ AIL+ A YD+ LI
Sbjct: 514 QVLGSKNGSTTCQ------------------CSHLSSFAILM---AHYDVEDWKLTLITR 552
Query: 244 VGVGQSEFAVADMVDMFVLLLPPAG 268
VG+ S F + + F+L+ P G
Sbjct: 553 VGLALSLFCLLLCILTFLLVRPIQG 577
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,171,566
Number of Sequences: 37866
Number of extensions: 721175
Number of successful extensions: 1909
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 1899
Number of HSP's gapped (non-prelim): 20
length of query: 418
length of database: 18,247,518
effective HSP length: 105
effective length of query: 313
effective length of database: 14,271,588
effective search space: 4467007044
effective search space used: 4467007044
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.