Search of human proteins with 254039650

Search of human proteins with 254039650

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens]
         (730 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens]           1466   0.0  
gi|20270305 synaptotagmin-like 5 isoform 1 [Homo sapiens]            1466   0.0  
gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens]           1453   0.0  
gi|193804862 synaptotagmin-like 4 [Homo sapiens]                      496   e-140
gi|193804860 synaptotagmin-like 4 [Homo sapiens]                      496   e-140
gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens]            271   2e-72
gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens]            271   2e-72
gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens]             263   4e-70
gi|46255064 synaptotagmin-like 2 isoform d [Homo sapiens]             260   4e-69
gi|46255062 synaptotagmin-like 2 isoform c [Homo sapiens]             260   4e-69
gi|15011900 synaptotagmin-like 2 isoform b [Homo sapiens]             259   6e-69
gi|46255066 synaptotagmin-like 2 isoform e [Homo sapiens]             259   6e-69
gi|46255068 synaptotagmin-like 2 isoform f [Homo sapiens]             254   2e-67
gi|244790016 synaptotagmin-like 2 isoform h [Homo sapiens]            251   2e-66
gi|14249614 synaptotagmin-like 1 [Homo sapiens]                       234   2e-61
gi|110227631 synaptotagmin-like 3 [Homo sapiens]                      221   2e-57
gi|92859638 synaptotagmin V [Homo sapiens]                            129   1e-29
gi|211059429 synaptotagmin II [Homo sapiens]                          124   4e-28
gi|31543670 synaptotagmin II [Homo sapiens]                           124   4e-28
gi|6005997 double C2-like domains, beta [Homo sapiens]                117   3e-26
gi|209447073 synaptotagmin I [Homo sapiens]                           116   6e-26
gi|5032139 synaptotagmin I [Homo sapiens]                             116   6e-26
gi|209447070 synaptotagmin I [Homo sapiens]                           116   6e-26
gi|38570146 synaptotagmin VII [Homo sapiens]                          112   9e-25
gi|47078261 double C2-like domains, alpha [Homo sapiens]              108   1e-23
gi|238550198 synaptotagmin III [Homo sapiens]                         108   2e-23
gi|238550196 synaptotagmin III [Homo sapiens]                         108   2e-23
gi|14150054 synaptotagmin III [Homo sapiens]                          108   2e-23
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]            105   1e-22
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]             105   1e-22

>gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens]
          Length = 730

 Score = 1466 bits (3795), Expect = 0.0
 Identities = 730/730 (100%), Positives = 730/730 (100%)

Query: 1   MSKNSEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTQQEA 60
           MSKNSEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTQQEA
Sbjct: 1   MSKNSEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTQQEA 60

Query: 61  SRVCVHCHRNLGLIFDRGDPCQACSLRVCRECRVAGPNGSWKCTVCDKIAQLRIITGEWF 120
           SRVCVHCHRNLGLIFDRGDPCQACSLRVCRECRVAGPNGSWKCTVCDKIAQLRIITGEWF
Sbjct: 61  SRVCVHCHRNLGLIFDRGDPCQACSLRVCRECRVAGPNGSWKCTVCDKIAQLRIITGEWF 120

Query: 121 FEEKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAEKSDTSPVAGKKASHDG 180
           FEEKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAEKSDTSPVAGKKASHDG
Sbjct: 121 FEEKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAEKSDTSPVAGKKASHDG 180

Query: 181 PKRKGFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLND 240
           PKRKGFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLND
Sbjct: 181 PKRKGFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLND 240

Query: 241 QEPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKS 300
           QEPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKS
Sbjct: 241 QEPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKS 300

Query: 301 HRRNTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVSIRSKSVPGALDKDSLEET 360
           HRRNTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVSIRSKSVPGALDKDSLEET
Sbjct: 301 HRRNTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVSIRSKSVPGALDKDSLEET 360

Query: 361 EESIDALVSSQLSTNTHRLASGLSTTSLNSMMSVYSETGDYGNVKVSGEILLHISYCYKT 420
           EESIDALVSSQLSTNTHRLASGLSTTSLNSMMSVYSETGDYGNVKVSGEILLHISYCYKT
Sbjct: 361 EESIDALVSSQLSTNTHRLASGLSTTSLNSMMSVYSETGDYGNVKVSGEILLHISYCYKT 420

Query: 421 GGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRTGTNPEFNETLKYT 480
           GGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRTGTNPEFNETLKYT
Sbjct: 421 GGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRTGTNPEFNETLKYT 480

Query: 481 ISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTDEWFVLQPKVEFAPDIG 540
           ISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTDEWFVLQPKVEFAPDIG
Sbjct: 481 ISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTDEWFVLQPKVEFAPDIG 540

Query: 541 LQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISGGILEVFIKEAKNLT 600
           LQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISGGILEVFIKEAKNLT
Sbjct: 541 LQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISGGILEVFIKEAKNLT 600

Query: 601 AVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLEL 660
           AVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLEL
Sbjct: 601 AVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLEL 660

Query: 661 TIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFEGVLM 720
           TIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFEGVLM
Sbjct: 661 TIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFEGVLM 720

Query: 721 LRSSMGKCRL 730
           LRSSMGKCRL
Sbjct: 721 LRSSMGKCRL 730


>gi|20270305 synaptotagmin-like 5 isoform 1 [Homo sapiens]
          Length = 730

 Score = 1466 bits (3795), Expect = 0.0
 Identities = 730/730 (100%), Positives = 730/730 (100%)

Query: 1   MSKNSEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTQQEA 60
           MSKNSEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTQQEA
Sbjct: 1   MSKNSEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTQQEA 60

Query: 61  SRVCVHCHRNLGLIFDRGDPCQACSLRVCRECRVAGPNGSWKCTVCDKIAQLRIITGEWF 120
           SRVCVHCHRNLGLIFDRGDPCQACSLRVCRECRVAGPNGSWKCTVCDKIAQLRIITGEWF
Sbjct: 61  SRVCVHCHRNLGLIFDRGDPCQACSLRVCRECRVAGPNGSWKCTVCDKIAQLRIITGEWF 120

Query: 121 FEEKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAEKSDTSPVAGKKASHDG 180
           FEEKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAEKSDTSPVAGKKASHDG
Sbjct: 121 FEEKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAEKSDTSPVAGKKASHDG 180

Query: 181 PKRKGFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLND 240
           PKRKGFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLND
Sbjct: 181 PKRKGFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLND 240

Query: 241 QEPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKS 300
           QEPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKS
Sbjct: 241 QEPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKS 300

Query: 301 HRRNTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVSIRSKSVPGALDKDSLEET 360
           HRRNTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVSIRSKSVPGALDKDSLEET
Sbjct: 301 HRRNTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVSIRSKSVPGALDKDSLEET 360

Query: 361 EESIDALVSSQLSTNTHRLASGLSTTSLNSMMSVYSETGDYGNVKVSGEILLHISYCYKT 420
           EESIDALVSSQLSTNTHRLASGLSTTSLNSMMSVYSETGDYGNVKVSGEILLHISYCYKT
Sbjct: 361 EESIDALVSSQLSTNTHRLASGLSTTSLNSMMSVYSETGDYGNVKVSGEILLHISYCYKT 420

Query: 421 GGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRTGTNPEFNETLKYT 480
           GGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRTGTNPEFNETLKYT
Sbjct: 421 GGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRTGTNPEFNETLKYT 480

Query: 481 ISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTDEWFVLQPKVEFAPDIG 540
           ISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTDEWFVLQPKVEFAPDIG
Sbjct: 481 ISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTDEWFVLQPKVEFAPDIG 540

Query: 541 LQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISGGILEVFIKEAKNLT 600
           LQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISGGILEVFIKEAKNLT
Sbjct: 541 LQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISGGILEVFIKEAKNLT 600

Query: 601 AVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLEL 660
           AVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLEL
Sbjct: 601 AVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLEL 660

Query: 661 TIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFEGVLM 720
           TIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFEGVLM
Sbjct: 661 TIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFEGVLM 720

Query: 721 LRSSMGKCRL 730
           LRSSMGKCRL
Sbjct: 721 LRSSMGKCRL 730


>gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens]
          Length = 752

 Score = 1453 bits (3762), Expect = 0.0
 Identities = 730/752 (97%), Positives = 730/752 (97%), Gaps = 22/752 (2%)

Query: 1   MSKNSEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTQQEA 60
           MSKNSEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTQQEA
Sbjct: 1   MSKNSEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTQQEA 60

Query: 61  SRVCVHCHRNLGLIFDRGDPCQACSLRVCRECRVAGPNGSWKCTVCDKIAQLRIITGEWF 120
           SRVCVHCHRNLGLIFDRGDPCQACSLRVCRECRVAGPNGSWKCTVCDKIAQLRIITGEWF
Sbjct: 61  SRVCVHCHRNLGLIFDRGDPCQACSLRVCRECRVAGPNGSWKCTVCDKIAQLRIITGEWF 120

Query: 121 FEEKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAEKSDTSPVAGKKASHDG 180
           FEEKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAEKSDTSPVAGKKASHDG
Sbjct: 121 FEEKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAEKSDTSPVAGKKASHDG 180

Query: 181 PKRKGFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLND 240
           PKRKGFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLND
Sbjct: 181 PKRKGFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLND 240

Query: 241 QEPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKS 300
           QEPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKS
Sbjct: 241 QEPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKS 300

Query: 301 HRRNTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVSIRSKSVPGALDKDSLEET 360
           HRRNTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVSIRSKSVPGALDKDSLEET
Sbjct: 301 HRRNTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVSIRSKSVPGALDKDSLEET 360

Query: 361 EESIDALVSSQLSTNTHRLASGLS----------------------TTSLNSMMSVYSET 398
           EESIDALVSSQLSTNTHRLASGLS                      TTSLNSMMSVYSET
Sbjct: 361 EESIDALVSSQLSTNTHRLASGLSTSSQAGSDRKWTYLNVPDADSDTTSLNSMMSVYSET 420

Query: 399 GDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRN 458
           GDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRN
Sbjct: 421 GDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRN 480

Query: 459 NKRKTKIRTGTNPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWN 518
           NKRKTKIRTGTNPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWN
Sbjct: 481 NKRKTKIRTGTNPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWN 540

Query: 519 FENPTDEWFVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKK 578
           FENPTDEWFVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKK
Sbjct: 541 FENPTDEWFVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKK 600

Query: 579 KESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQ 638
           KESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQ
Sbjct: 601 KESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQ 660

Query: 639 WNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQG 698
           WNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQG
Sbjct: 661 WNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQG 720

Query: 699 EEQRLWQKMANNPGTPFEGVLMLRSSMGKCRL 730
           EEQRLWQKMANNPGTPFEGVLMLRSSMGKCRL
Sbjct: 721 EEQRLWQKMANNPGTPFEGVLMLRSSMGKCRL 752


>gi|193804862 synaptotagmin-like 4 [Homo sapiens]
          Length = 671

 Score =  496 bits (1277), Expect = e-140
 Identities = 296/732 (40%), Positives = 420/732 (57%), Gaps = 70/732 (9%)

Query: 5   SEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGK--TQQEASR 62
           SE ++LSFL + EK++IL VL+RDE ++K ++KRIR+LKNELLE KR+  K  +Q  + R
Sbjct: 2   SELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSDR 61

Query: 63  VCVHCHRNLGLIFDRGDPCQACSLRVCRECRVAGPNGSWKCTVCDKIAQLRIITGEWFFE 122
            C  C  +LG +  + + C+ C+  VCR+CR+   NG+W+C VC K  +L+  TG+WF++
Sbjct: 62  TCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFYD 121

Query: 123 EKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQT-RQDAEKSDTSPVAGKKASHDGP 181
           +K  RF      G++++R S LR  P   + ++  Q+     +  D  P  G+K   +  
Sbjct: 122 QKVNRFAYRT--GSEIIRMS-LRHKPAVSKRETVGQSLLHQTQMGDIWP--GRKIIQERQ 176

Query: 182 KRKGFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLNDQ 241
           K    L              PK  +G+S +L+ + +   S      +D  ST   D  D+
Sbjct: 177 KEPSVLFE-----------VPKLKSGKS-ALEAESESLDSFT----ADSDSTSRRDSLDK 220

Query: 242 EPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKSH 301
                       +G+ P  +   AP ++        + G +N + +   E   ++ T+  
Sbjct: 221 ------------SGLFPEWKKMSAPKSQVEKET---QPGGQNVVFVDEGEMIFKKNTRKI 265

Query: 302 RRNTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVSIRSKSVPGALDKDSLEETE 361
            R                S+ ++S +DL          ++  RSKSVPG       EE E
Sbjct: 266 LR---------------PSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGLNVDMEEEEEE 310

Query: 362 ESIDALVS-SQLSTNTHRLASGLSTTSLNSMMSVYSETGDYGNVKVSGEILLHISYCYKT 420
           E ID LV   +       + SG S +++ SMMS+YSE GD+GN+ V+G I   + Y  +T
Sbjct: 311 EDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRIAFSLKYEQQT 370

Query: 421 GGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRTGT-NPEFNETLKY 479
             L + VK C  LA  DE K+R++ YVK+YLLPDKSR  KRKT I+  T NP ++ETL+Y
Sbjct: 371 QSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDETLRY 430

Query: 480 TISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTDEWFVLQPKVEFAPDI 539
            I  + L  RTLQ SVWH+ RFGRN+FLGE EI  DSW  +   D    L  K+      
Sbjct: 431 EIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPLHGKISAESPT 490

Query: 540 GL-QYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISGGILEVFIKEAKN 598
           GL  +KGEL V L+YIP              +KT   G +K+S    GG L+V+IKEAKN
Sbjct: 491 GLPSHKGELVVSLKYIP-------------ASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537

Query: 599 LTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCL 658
           LTA K+GGTSDSFVKGYLLP  +KA+K KT V+KK++NP +NHTF+++G+  +D++++CL
Sbjct: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597

Query: 659 ELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFEGV 718
           ELT+WD+E  +SN FLGGVRL  G+G+S+G+ VDWMDS GEE  LWQKM   PG+  EG 
Sbjct: 598 ELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGT 657

Query: 719 LMLRSSMGKCRL 730
           L LRSSM K +L
Sbjct: 658 LQLRSSMAKQKL 669


>gi|193804860 synaptotagmin-like 4 [Homo sapiens]
          Length = 671

 Score =  496 bits (1277), Expect = e-140
 Identities = 296/732 (40%), Positives = 420/732 (57%), Gaps = 70/732 (9%)

Query: 5   SEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGK--TQQEASR 62
           SE ++LSFL + EK++IL VL+RDE ++K ++KRIR+LKNELLE KR+  K  +Q  + R
Sbjct: 2   SELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSDR 61

Query: 63  VCVHCHRNLGLIFDRGDPCQACSLRVCRECRVAGPNGSWKCTVCDKIAQLRIITGEWFFE 122
            C  C  +LG +  + + C+ C+  VCR+CR+   NG+W+C VC K  +L+  TG+WF++
Sbjct: 62  TCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFYD 121

Query: 123 EKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQT-RQDAEKSDTSPVAGKKASHDGP 181
           +K  RF      G++++R S LR  P   + ++  Q+     +  D  P  G+K   +  
Sbjct: 122 QKVNRFAYRT--GSEIIRMS-LRHKPAVSKRETVGQSLLHQTQMGDIWP--GRKIIQERQ 176

Query: 182 KRKGFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLNDQ 241
           K    L              PK  +G+S +L+ + +   S      +D  ST   D  D+
Sbjct: 177 KEPSVLFE-----------VPKLKSGKS-ALEAESESLDSFT----ADSDSTSRRDSLDK 220

Query: 242 EPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKSH 301
                       +G+ P  +   AP ++        + G +N + +   E   ++ T+  
Sbjct: 221 ------------SGLFPEWKKMSAPKSQVEKET---QPGGQNVVFVDEGEMIFKKNTRKI 265

Query: 302 RRNTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVSIRSKSVPGALDKDSLEETE 361
            R                S+ ++S +DL          ++  RSKSVPG       EE E
Sbjct: 266 LR---------------PSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGLNVDMEEEEEE 310

Query: 362 ESIDALVS-SQLSTNTHRLASGLSTTSLNSMMSVYSETGDYGNVKVSGEILLHISYCYKT 420
           E ID LV   +       + SG S +++ SMMS+YSE GD+GN+ V+G I   + Y  +T
Sbjct: 311 EDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRIAFSLKYEQQT 370

Query: 421 GGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRTGT-NPEFNETLKY 479
             L + VK C  LA  DE K+R++ YVK+YLLPDKSR  KRKT I+  T NP ++ETL+Y
Sbjct: 371 QSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDETLRY 430

Query: 480 TISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTDEWFVLQPKVEFAPDI 539
            I  + L  RTLQ SVWH+ RFGRN+FLGE EI  DSW  +   D    L  K+      
Sbjct: 431 EIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPLHGKISAESPT 490

Query: 540 GL-QYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISGGILEVFIKEAKN 598
           GL  +KGEL V L+YIP              +KT   G +K+S    GG L+V+IKEAKN
Sbjct: 491 GLPSHKGELVVSLKYIP-------------ASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537

Query: 599 LTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCL 658
           LTA K+GGTSDSFVKGYLLP  +KA+K KT V+KK++NP +NHTF+++G+  +D++++CL
Sbjct: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597

Query: 659 ELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFEGV 718
           ELT+WD+E  +SN FLGGVRL  G+G+S+G+ VDWMDS GEE  LWQKM   PG+  EG 
Sbjct: 598 ELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGT 657

Query: 719 LMLRSSMGKCRL 730
           L LRSSM K +L
Sbjct: 658 LQLRSSMAKQKL 669


>gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens]
          Length = 935

 Score =  271 bits (692), Expect = 2e-72
 Identities = 202/622 (32%), Positives = 314/622 (50%), Gaps = 80/622 (12%)

Query: 130 QVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAE-----KSDTSPVAGKKASHDGPKRK 184
           + +VL +D ++   +  +   EE QS  +  Q  +     +S +SP   K  +H      
Sbjct: 356 EFSVLESDRLKNG-MEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSG 414

Query: 185 GFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLNDQEPG 244
            F ++   S    E++T +                +S+++ P  +     SS+L   E  
Sbjct: 415 SFPINGLHS--HSEVLTARP---------------QSMENSPTINEPKDKSSELTRLESV 457

Query: 245 -PRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFEN--SMDLAAIE-GTSQELTKS 300
            PR+P    S+ V P     P  S+R       R+ G E   S  L  +E   ++++   
Sbjct: 458 LPRSPADELSHCVEPEPSQVPGGSSR------DRQQGSEEEPSPVLKTLERSAARKMPSK 511

Query: 301 HRRNTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSE-----DTVSIRSKSVPGALDKD 355
              + S   S      +   +  RS  D+S   T+        D +   SKSVP  L  +
Sbjct: 512 SLEDISSDSSNQAKVDNQPEELVRSAEDVSTVPTQPDNPFSHPDKLKRMSKSVPAFLQDE 571

Query: 356 SLEETEESIDALVSSQLS------TNTHRLASGLSTTSLNSM----MSVYSETGDYGNVK 405
           S ++ E    +  S QLS      ++   L+S    TSL+S+    MSVYS  GD+GN++
Sbjct: 572 S-DDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYS--GDFGNLE 628

Query: 406 VSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKI 465
           V G I   I Y      L++FV  C++LA  D KKQR+D YVK+YLLPDK +  K+KT +
Sbjct: 629 VKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLV 688

Query: 466 RTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTD 524
              T NP +NE L+Y I    L+T+ L LS+WH D F RNSFLGEVE+  ++W+++N  +
Sbjct: 689 VKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQN 748

Query: 525 E---WFVLQPKVEFAP-DIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKE 580
           +   W+ L+ K   AP  +  + +GE+ + L+Y+         PE + G K         
Sbjct: 749 KQLRWYPLKRKT--APVALEAENRGEMKLALQYV---------PEPVPGKK--------- 788

Query: 581 SPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWN 640
             + + G + +++KE  +L  ++ G   +SFVK  +LPD S+ ++ KT  + K+ NP +N
Sbjct: 789 --LPTTGEVHIWVKECLDLPLLR-GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFN 845

Query: 641 HTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEE 700
           HT ++ G  P+D+   C+ELT+WD     +N FLGG+R+  G+G S+G  VDWMDS  EE
Sbjct: 846 HTMVYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEE 904

Query: 701 QRLWQKMANNPGTPFEGVLMLR 722
             LW+KM N+P T  E  L LR
Sbjct: 905 VALWEKMVNSPNTWIEATLPLR 926



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 23/56 (41%), Positives = 36/56 (64%), Gaps = 3/56 (5%)

Query: 8  INLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNEL---LEAKRRSGKTQQEA 60
          I+LSFL + E+E I+ VL+RD  LK+ E++R+R L  ++    + K  SG+   EA
Sbjct: 2  IDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEA 57



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 56/263 (21%), Positives = 112/263 (42%), Gaps = 32/263 (12%)

Query: 111 QLRIITGEWFFEEKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAEKSDTSP 170
           QL+ ++G+WF+E KAKR +   + G D++R S+ ++ P     QS+++    A++S  + 
Sbjct: 45  QLKNMSGQWFYEAKAKRHRD-KIHGADIIRASMRKKRPQIAAEQSKDR-ENGAKESWVNN 102

Query: 171 VAGKKASHDGPKRKGFLLSKFRSAT----RGEIITPKTDTGRSYSLDLDGQHFRSLK-SP 225
           V   K +   P+  G +      A        ++ P +       +D+  ++ R    SP
Sbjct: 103 V--NKDAFLPPELAGVVEEPEEDAAPASPSSSVVNPASSV-----IDMSQENTRKPNVSP 155

Query: 226 PGSDRGSTGSSDLNDQEPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSM 285
               +    SS L +     +T      NG             RT     S+E     S 
Sbjct: 156 EKQRKNPFNSSKLPEGHSSQQTKNEQSKNG-------------RTGLFQTSKEDELSESK 202

Query: 286 DLAAIEGTS-QELTKSHRR---NTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTV 341
           + + +  TS Q+L KS +     ++G+   A    +       ++L+  ++ +   + T 
Sbjct: 203 EKSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARKMIYKSTDLNKDDNQSFPRQRTD 262

Query: 342 SIRSKSVP-GALDKDSLEETEES 363
           S++++  P G L ++S   + +S
Sbjct: 263 SLKARGAPRGILKRNSSSSSTDS 285


>gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens]
          Length = 934

 Score =  271 bits (692), Expect = 2e-72
 Identities = 202/622 (32%), Positives = 314/622 (50%), Gaps = 80/622 (12%)

Query: 130 QVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAE-----KSDTSPVAGKKASHDGPKRK 184
           + +VL +D ++   +  +   EE QS  +  Q  +     +S +SP   K  +H      
Sbjct: 355 EFSVLESDRLKNG-MEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSG 413

Query: 185 GFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLNDQEPG 244
            F ++   S    E++T +                +S+++ P  +     SS+L   E  
Sbjct: 414 SFPINGLHS--HSEVLTARP---------------QSMENSPTINEPKDKSSELTRLESV 456

Query: 245 -PRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFEN--SMDLAAIE-GTSQELTKS 300
            PR+P    S+ V P     P  S+R       R+ G E   S  L  +E   ++++   
Sbjct: 457 LPRSPADELSHCVEPEPSQVPGGSSR------DRQQGSEEEPSPVLKTLERSAARKMPSK 510

Query: 301 HRRNTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSE-----DTVSIRSKSVPGALDKD 355
              + S   S      +   +  RS  D+S   T+        D +   SKSVP  L  +
Sbjct: 511 SLEDISSDSSNQAKVDNQPEELVRSAEDVSTVPTQPDNPFSHPDKLKRMSKSVPAFLQDE 570

Query: 356 SLEETEESIDALVSSQLS------TNTHRLASGLSTTSLNSM----MSVYSETGDYGNVK 405
           S ++ E    +  S QLS      ++   L+S    TSL+S+    MSVYS  GD+GN++
Sbjct: 571 S-DDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYS--GDFGNLE 627

Query: 406 VSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKI 465
           V G I   I Y      L++FV  C++LA  D KKQR+D YVK+YLLPDK +  K+KT +
Sbjct: 628 VKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLV 687

Query: 466 RTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTD 524
              T NP +NE L+Y I    L+T+ L LS+WH D F RNSFLGEVE+  ++W+++N  +
Sbjct: 688 VKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQN 747

Query: 525 E---WFVLQPKVEFAP-DIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKE 580
           +   W+ L+ K   AP  +  + +GE+ + L+Y+         PE + G K         
Sbjct: 748 KQLRWYPLKRKT--APVALEAENRGEMKLALQYV---------PEPVPGKK--------- 787

Query: 581 SPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWN 640
             + + G + +++KE  +L  ++ G   +SFVK  +LPD S+ ++ KT  + K+ NP +N
Sbjct: 788 --LPTTGEVHIWVKECLDLPLLR-GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFN 844

Query: 641 HTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEE 700
           HT ++ G  P+D+   C+ELT+WD     +N FLGG+R+  G+G S+G  VDWMDS  EE
Sbjct: 845 HTMVYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEE 903

Query: 701 QRLWQKMANNPGTPFEGVLMLR 722
             LW+KM N+P T  E  L LR
Sbjct: 904 VALWEKMVNSPNTWIEATLPLR 925



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 55/262 (20%), Positives = 111/262 (42%), Gaps = 31/262 (11%)

Query: 111 QLRIITGEWFFEEKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAEKSDTSP 170
           QL+ ++G+WF+E KAKR +   + G D++R S+ ++ P     QS+++    A++S  + 
Sbjct: 45  QLKNMSGQWFYEAKAKRHRD-KIHGADIIRASMRKKRPQIAAEQSKDR-ENGAKESWVNN 102

Query: 171 VAGKKASHDGPKRKGFLLSKFRSAT----RGEIITPKTDTGRSYSLDLDGQHFRSLKSPP 226
           V   K +   P+  G +      A        ++ P +       +D+  ++ R     P
Sbjct: 103 V--NKDAFLPPELAGVVEEPEEDAAPASPSSSVVNPASSV-----IDMSQENTRKPNVSP 155

Query: 227 GSDRGSTGSSDLNDQEPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMD 286
              +    SS L +     +T      NG             RT     S+E     S +
Sbjct: 156 EKRKNPFNSSKLPEGHSSQQTKNEQSKNG-------------RTGLFQTSKEDELSESKE 202

Query: 287 LAAIEGTS-QELTKSHRR---NTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVS 342
            + +  TS Q+L KS +     ++G+   A    +       ++L+  ++ +   + T S
Sbjct: 203 KSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARKMIYKSTDLNKDDNQSFPRQRTDS 262

Query: 343 IRSKSVP-GALDKDSLEETEES 363
           ++++  P G L ++S   + +S
Sbjct: 263 LKARGAPRGILKRNSSSSSTDS 284



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 23/56 (41%), Positives = 36/56 (64%), Gaps = 3/56 (5%)

Query: 8  INLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNEL---LEAKRRSGKTQQEA 60
          I+LSFL + E+E I+ VL+RD  LK+ E++R+R L  ++    + K  SG+   EA
Sbjct: 2  IDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEA 57


>gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens]
          Length = 910

 Score =  263 bits (672), Expect = 4e-70
 Identities = 191/605 (31%), Positives = 295/605 (48%), Gaps = 70/605 (11%)

Query: 130 QVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAE-----KSDTSPVAGKKASHDGPKRK 184
           + +VL +D ++   +  +   EE QS  +  Q  +     +S +SP   K  +H      
Sbjct: 355 EFSVLESDRLKNG-MEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSG 413

Query: 185 GFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLNDQEPG 244
            F ++   S    E++T +                +S+++ P  +     SS+L   E  
Sbjct: 414 SFPINGLHS--HSEVLTARP---------------QSMENSPTINEPKDKSSELTRLESV 456

Query: 245 -PRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKSHRR 303
            PR+P    S+ V P     P  S+R       R+ G E        E  S  L    R 
Sbjct: 457 LPRSPADELSHCVEPEPSQVPGGSSR------DRQQGSE--------EEPSPVLKTLERS 502

Query: 304 NTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVSIRSKSVPG-ALDKDSLEETEE 362
                PS ++   S  S       +  E     +ED      K V    + + S   T+ 
Sbjct: 503 AARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAEDDEKPDQKPVTNECVPRISTVPTQP 562

Query: 363 SIDALVSSQLSTNTHRLASGLSTTSLNSMMSVYSETGDYGNVKVSGEILLHISYCYKTGG 422
                   +L   +  + + L      S+MSVYS  GD+GN++V G I   I Y      
Sbjct: 563 DNPFSHPDKLKRMSKSVPAFLQDEVSGSVMSVYS--GDFGNLEVKGNIQFAIEYVESLKE 620

Query: 423 LYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRTGT-NPEFNETLKYTI 481
           L++FV  C++LA  D KKQR+D YVK+YLLPDK +  K+KT +   T NP +NE L+Y I
Sbjct: 621 LHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKI 680

Query: 482 SHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTDE---WFVLQPKVEFAP- 537
               L+T+ L LS+WH D F RNSFLGEVE+  ++W+++N  ++   W+ L+ K   AP 
Sbjct: 681 EKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKT--APV 738

Query: 538 DIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISGGILEVFIKEAK 597
            +  + +GE+ + L+Y+         PE + G K           + + G + +++KE  
Sbjct: 739 ALEAENRGEMKLALQYV---------PEPVPGKK-----------LPTTGEVHIWVKECL 778

Query: 598 NLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVC 657
           +L  ++ G   +SFVK  +LPD S+ ++ KT  + K+ NP +NHT ++ G  P+D+   C
Sbjct: 779 DLPLLR-GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEAC 837

Query: 658 LELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFEG 717
           +ELT+WD     +N FLGG+R+  G+G S+G  VDWMDS  EE  LW+KM N+P T  E 
Sbjct: 838 VELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEA 896

Query: 718 VLMLR 722
            L LR
Sbjct: 897 TLPLR 901



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 55/262 (20%), Positives = 111/262 (42%), Gaps = 31/262 (11%)

Query: 111 QLRIITGEWFFEEKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAEKSDTSP 170
           QL+ ++G+WF+E KAKR +   + G D++R S+ ++ P     QS+++    A++S  + 
Sbjct: 45  QLKNMSGQWFYEAKAKRHRD-KIHGADIIRASMRKKRPQIAAEQSKDR-ENGAKESWVNN 102

Query: 171 VAGKKASHDGPKRKGFLLSKFRSAT----RGEIITPKTDTGRSYSLDLDGQHFRSLKSPP 226
           V   K +   P+  G +      A        ++ P +       +D+  ++ R     P
Sbjct: 103 V--NKDAFLPPELAGVVEEPEEDAAPASPSSSVVNPASSV-----IDMSQENTRKPNVSP 155

Query: 227 GSDRGSTGSSDLNDQEPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMD 286
              +    SS L +     +T      NG             RT     S+E     S +
Sbjct: 156 EKRKNPFNSSKLPEGHSSQQTKNEQSKNG-------------RTGLFQTSKEDELSESKE 202

Query: 287 LAAIEGTS-QELTKSHRR---NTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVS 342
            + +  TS Q+L KS +     ++G+   A    +       ++L+  ++ +   + T S
Sbjct: 203 KSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARKMIYKSTDLNKDDNQSFPRQRTDS 262

Query: 343 IRSKSVP-GALDKDSLEETEES 363
           ++++  P G L ++S   + +S
Sbjct: 263 LKARGAPRGILKRNSSSSSTDS 284



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 23/56 (41%), Positives = 36/56 (64%), Gaps = 3/56 (5%)

Query: 8  INLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNEL---LEAKRRSGKTQQEA 60
          I+LSFL + E+E I+ VL+RD  LK+ E++R+R L  ++    + K  SG+   EA
Sbjct: 2  IDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEA 57


>gi|46255064 synaptotagmin-like 2 isoform d [Homo sapiens]
          Length = 1256

 Score =  260 bits (664), Expect = 4e-69
 Identities = 157/399 (39%), Positives = 232/399 (58%), Gaps = 42/399 (10%)

Query: 339  DTVSIRSKSVPGALDKDSLEETEESIDALVSSQLS------TNTHRLASGLSTTSLNSM- 391
            D +   SKSVP  L  +S ++ E    +  S QLS      ++   L+S    TSL+S+ 
Sbjct: 876  DKLKRMSKSVPAFLQDES-DDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVS 934

Query: 392  ---MSVYSETGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVK 448
               MSVYS  GD+GN++V G I   I Y      L++FV  C++LA  D KKQR+D YVK
Sbjct: 935  GSVMSVYS--GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVK 992

Query: 449  SYLLPDKSRNNKRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFL 507
            +YLLPDK +  K+KT +   T NP +NE L+Y I    L+T+ L LS+WH D F RNSFL
Sbjct: 993  AYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFL 1052

Query: 508  GEVEIPFDSWNFENPTDE---WFVLQPKVEFAP-DIGLQYKGELTVVLRYIPPEENLMLP 563
            GEVE+  ++W+++N  ++   W+ L+ K   AP  +  + +GE+ + L+Y+         
Sbjct: 1053 GEVELDLETWDWDNKQNKQLRWYPLKRKT--APVALEAENRGEMKLALQYV--------- 1101

Query: 564  PEQLQGNKTFKKGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKA 623
            PE + G K           + + G + +++KE  +L  ++ G   +SFVK  +LPD S+ 
Sbjct: 1102 PEPVPGKK-----------LPTTGEVHIWVKECLDLPLLR-GSHLNSFVKCTILPDTSRK 1149

Query: 624  TKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGS 683
            ++ KT  + K+ NP +NHT ++ G  P+D+   C+ELT+WD     +N FLGG+R+  G+
Sbjct: 1150 SRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGFGT 1208

Query: 684  GVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFEGVLMLR 722
            G S+G  VDWMDS  EE  LW+KM N+P T  E  L LR
Sbjct: 1209 GKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLR 1247


>gi|46255062 synaptotagmin-like 2 isoform c [Homo sapiens]
          Length = 1272

 Score =  260 bits (664), Expect = 4e-69
 Identities = 157/399 (39%), Positives = 232/399 (58%), Gaps = 42/399 (10%)

Query: 339  DTVSIRSKSVPGALDKDSLEETEESIDALVSSQLS------TNTHRLASGLSTTSLNSM- 391
            D +   SKSVP  L  +S ++ E    +  S QLS      ++   L+S    TSL+S+ 
Sbjct: 892  DKLKRMSKSVPAFLQDES-DDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVS 950

Query: 392  ---MSVYSETGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVK 448
               MSVYS  GD+GN++V G I   I Y      L++FV  C++LA  D KKQR+D YVK
Sbjct: 951  GSVMSVYS--GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVK 1008

Query: 449  SYLLPDKSRNNKRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFL 507
            +YLLPDK +  K+KT +   T NP +NE L+Y I    L+T+ L LS+WH D F RNSFL
Sbjct: 1009 AYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFL 1068

Query: 508  GEVEIPFDSWNFENPTDE---WFVLQPKVEFAP-DIGLQYKGELTVVLRYIPPEENLMLP 563
            GEVE+  ++W+++N  ++   W+ L+ K   AP  +  + +GE+ + L+Y+         
Sbjct: 1069 GEVELDLETWDWDNKQNKQLRWYPLKRKT--APVALEAENRGEMKLALQYV--------- 1117

Query: 564  PEQLQGNKTFKKGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKA 623
            PE + G K           + + G + +++KE  +L  ++ G   +SFVK  +LPD S+ 
Sbjct: 1118 PEPVPGKK-----------LPTTGEVHIWVKECLDLPLLR-GSHLNSFVKCTILPDTSRK 1165

Query: 624  TKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGS 683
            ++ KT  + K+ NP +NHT ++ G  P+D+   C+ELT+WD     +N FLGG+R+  G+
Sbjct: 1166 SRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGFGT 1224

Query: 684  GVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFEGVLMLR 722
            G S+G  VDWMDS  EE  LW+KM N+P T  E  L LR
Sbjct: 1225 GKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLR 1263


>gi|15011900 synaptotagmin-like 2 isoform b [Homo sapiens]
          Length = 376

 Score =  259 bits (662), Expect = 6e-69
 Identities = 156/393 (39%), Positives = 230/393 (58%), Gaps = 42/393 (10%)

Query: 345 SKSVPGALDKDSLEETEESIDALVSSQLS------TNTHRLASGLSTTSLNSM----MSV 394
           SKSVP  L  +S ++ E    +  S QLS      ++   L+S    TSL+S+    MSV
Sbjct: 2   SKSVPAFLQDES-DDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV 60

Query: 395 YSETGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPD 454
           YS  GD+GN++V G I   I Y      L++FV  C++LA  D KKQR+D YVK+YLLPD
Sbjct: 61  YS--GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPD 118

Query: 455 KSRNNKRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIP 513
           K +  K+KT +   T NP +NE L+Y I    L+T+ L LS+WH D F RNSFLGEVE+ 
Sbjct: 119 KGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD 178

Query: 514 FDSWNFENPTDE---WFVLQPKVEFAP-DIGLQYKGELTVVLRYIPPEENLMLPPEQLQG 569
            ++W+++N  ++   W+ L+ K   AP  +  + +GE+ + L+Y+         PE + G
Sbjct: 179 LETWDWDNKQNKQLRWYPLKRKT--APVALEAENRGEMKLALQYV---------PEPVPG 227

Query: 570 NKTFKKGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTL 629
            K           + + G + +++KE  +L  ++ G   +SFVK  +LPD S+ ++ KT 
Sbjct: 228 KK-----------LPTTGEVHIWVKECLDLPLLR-GSHLNSFVKCTILPDTSRKSRQKTR 275

Query: 630 VIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGK 689
            + K+ NP +NHT ++ G  P+D+   C+ELT+WD     +N FLGG+R+  G+G S+G 
Sbjct: 276 AVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGT 334

Query: 690 NVDWMDSQGEEQRLWQKMANNPGTPFEGVLMLR 722
            VDWMDS  EE  LW+KM N+P T  E  L LR
Sbjct: 335 EVDWMDSTSEEVALWEKMVNSPNTWIEATLPLR 367


>gi|46255066 synaptotagmin-like 2 isoform e [Homo sapiens]
          Length = 376

 Score =  259 bits (662), Expect = 6e-69
 Identities = 156/393 (39%), Positives = 230/393 (58%), Gaps = 42/393 (10%)

Query: 345 SKSVPGALDKDSLEETEESIDALVSSQLS------TNTHRLASGLSTTSLNSM----MSV 394
           SKSVP  L  +S ++ E    +  S QLS      ++   L+S    TSL+S+    MSV
Sbjct: 2   SKSVPAFLQDES-DDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV 60

Query: 395 YSETGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPD 454
           YS  GD+GN++V G I   I Y      L++FV  C++LA  D KKQR+D YVK+YLLPD
Sbjct: 61  YS--GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPD 118

Query: 455 KSRNNKRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIP 513
           K +  K+KT +   T NP +NE L+Y I    L+T+ L LS+WH D F RNSFLGEVE+ 
Sbjct: 119 KGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD 178

Query: 514 FDSWNFENPTDE---WFVLQPKVEFAP-DIGLQYKGELTVVLRYIPPEENLMLPPEQLQG 569
            ++W+++N  ++   W+ L+ K   AP  +  + +GE+ + L+Y+         PE + G
Sbjct: 179 LETWDWDNKQNKQLRWYPLKRKT--APVALEAENRGEMKLALQYV---------PEPVPG 227

Query: 570 NKTFKKGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTL 629
            K           + + G + +++KE  +L  ++ G   +SFVK  +LPD S+ ++ KT 
Sbjct: 228 KK-----------LPTTGEVHIWVKECLDLPLLR-GSHLNSFVKCTILPDTSRKSRQKTR 275

Query: 630 VIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGK 689
            + K+ NP +NHT ++ G  P+D+   C+ELT+WD     +N FLGG+R+  G+G S+G 
Sbjct: 276 AVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGT 334

Query: 690 NVDWMDSQGEEQRLWQKMANNPGTPFEGVLMLR 722
            VDWMDS  EE  LW+KM N+P T  E  L LR
Sbjct: 335 EVDWMDSTSEEVALWEKMVNSPNTWIEATLPLR 367


>gi|46255068 synaptotagmin-like 2 isoform f [Homo sapiens]
          Length = 365

 Score =  254 bits (650), Expect = 2e-67
 Identities = 147/379 (38%), Positives = 222/379 (58%), Gaps = 35/379 (9%)

Query: 353 DKDSLEETEESIDALVSSQLSTNTHRLASGLSTTSLNSM----MSVYSETGDYGNVKVSG 408
           D+++   +E S       +  ++   L+S    TSL+S+    MSVYS  GD+GN++V G
Sbjct: 4   DRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYS--GDFGNLEVKG 61

Query: 409 EILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRTG 468
            I   I Y      L++FV  C++LA  D KKQR+D YVK+YLLPDK +  K+KT +   
Sbjct: 62  NIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKK 121

Query: 469 T-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTDE-- 525
           T NP +NE L+Y I    L+T+ L LS+WH D F RNSFLGEVE+  ++W+++N  ++  
Sbjct: 122 TLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL 181

Query: 526 -WFVLQPKVEFAP-DIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPV 583
            W+ L+ K   AP  +  + +GE+ + L+Y+         PE + G K           +
Sbjct: 182 RWYPLKRKT--APVALEAENRGEMKLALQYV---------PEPVPGKK-----------L 219

Query: 584 ISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTF 643
            + G + +++KE  +L  ++ G   +SFVK  +LPD S+ ++ KT  + K+ NP +NHT 
Sbjct: 220 PTTGEVHIWVKECLDLPLLR-GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTM 278

Query: 644 MFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRL 703
           ++ G  P+D+   C+ELT+WD     +N FLGG+R+  G+G S+G  VDWMDS  EE  L
Sbjct: 279 VYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVAL 337

Query: 704 WQKMANNPGTPFEGVLMLR 722
           W+KM N+P T  E  L LR
Sbjct: 338 WEKMVNSPNTWIEATLPLR 356


>gi|244790016 synaptotagmin-like 2 isoform h [Homo sapiens]
          Length = 336

 Score =  251 bits (641), Expect = 2e-66
 Identities = 139/338 (41%), Positives = 205/338 (60%), Gaps = 31/338 (9%)

Query: 390 SMMSVYSETGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKS 449
           S+MSVYS  GD+GN++V G I   I Y      L++FV  C++LA  D KKQR+D YVK+
Sbjct: 16  SVMSVYS--GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKA 73

Query: 450 YLLPDKSRNNKRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLG 508
           YLLPDK +  K+KT +   T NP +NE L+Y I    L+T+ L LS+WH D F RNSFLG
Sbjct: 74  YLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLG 133

Query: 509 EVEIPFDSWNFENPTDE---WFVLQPKVEFAP-DIGLQYKGELTVVLRYIPPEENLMLPP 564
           EVE+  ++W+++N  ++   W+ L+ K   AP  +  + +GE+ + L+Y+         P
Sbjct: 134 EVELDLETWDWDNKQNKQLRWYPLKRKT--APVALEAENRGEMKLALQYV---------P 182

Query: 565 EQLQGNKTFKKGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKAT 624
           E + G K           + + G + +++KE  +L  ++ G   +SFVK  +LPD S+ +
Sbjct: 183 EPVPGKK-----------LPTTGEVHIWVKECLDLPLLR-GSHLNSFVKCTILPDTSRKS 230

Query: 625 KHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSG 684
           + KT  + K+ NP +NHT ++ G  P+D+   C+ELT+WD     +N FLGG+R+  G+G
Sbjct: 231 RQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGFGTG 289

Query: 685 VSHGKNVDWMDSQGEEQRLWQKMANNPGTPFEGVLMLR 722
            S+G  VDWMDS  EE  LW+KM N+P T  E  L LR
Sbjct: 290 KSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLR 327


>gi|14249614 synaptotagmin-like 1 [Homo sapiens]
          Length = 550

 Score =  234 bits (597), Expect = 2e-61
 Identities = 139/353 (39%), Positives = 211/353 (59%), Gaps = 36/353 (10%)

Query: 379 LASGLSTTSLNSMM---SVYSETGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAI 435
           L+S  S +SLNS     S  S +GD   V+V G +   + Y      L + V  C+ LA 
Sbjct: 224 LSSSSSVSSLNSSTLSGSQMSLSGDAEAVQVRGSVHFALHYEPGAAELRVHVIQCQGLAA 283

Query: 436 GDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRT-GTNPEFNETLKYTISHTQLETRTLQLS 494
              +++R+D YVKSYLLPDK   +KRKT ++    NP FNETL+Y++   +L+ R L LS
Sbjct: 284 A--RRRRSDPYVKSYLLPDKQ--SKRKTAVKKRNLNPVFNETLRYSVPQAELQGRVLSLS 339

Query: 495 VWHYDRFGRNSFLGEVEIPFDSWNF-ENPTDEWFVLQPKVEFAPDIGLQYKGELTVVLRY 553
           VWH +  GRN FLGEVE+P D+W++   PT  W  LQP+V  +PD  L  +G L + L+Y
Sbjct: 340 VWHRESLGRNIFLGEVEVPLDTWDWGSEPT--WLPLQPRVPPSPD-DLPSRGLLALSLKY 396

Query: 554 IPP-EENLMLPPEQLQGNKTFKKGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFV 612
           +P   E   LPP                      G L  ++KEA++L  +++ G+ D++V
Sbjct: 397 VPAGSEGAGLPP---------------------SGELHFWVKEARDLLPLRA-GSLDTYV 434

Query: 613 KGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNI 672
           + ++LPDDS+A++ +T V+++S++P +NHT ++ G  P D++  C EL++WD  A  +N 
Sbjct: 435 QCFVLPDDSQASRQRTRVVRRSLSPVFNHTMVYDGFGPADLRQACAELSLWDHGAL-ANR 493

Query: 673 FLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFEGVLMLRSSM 725
            LGG RL+ G+G S+G  V WMDS  EE++LWQ +   P    +G+L LR+++
Sbjct: 494 QLGGTRLSLGTGSSYGLQVPWMDSTPEEKQLWQALLEQPCEWVDGLLPLRTNL 546



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 40/182 (21%), Positives = 81/182 (44%), Gaps = 21/182 (11%)

Query: 86  LRVCRECRVAGPNGSWKCTVCDKIAQLRIITGEWFFEEKAKRFKQVNVLGTDVVRQSILR 145
           LR   E RV+      + +V D   QL+I+TG+WF E +++R    +  G+D+VR S+ R
Sbjct: 55  LRQLEEGRVS----KLRASVADP-GQLKILTGDWFQEARSQRHHNAH-FGSDLVRASMRR 108

Query: 146 -RSPGAEEVQSQEQTRQDAEKSDTSPVAGKKASHDGPKRKGFLLSKFRSATRGEIITPKT 204
            +S   ++    ++  + A K        +    + P+ +   L +  ++   E    + 
Sbjct: 109 KKSTRGDQAPGHDREAEAAVKEKEEGPEPRLTIDEAPQER---LRETEASDPEEASQAQE 165

Query: 205 DTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLNDQEPGPRTPKSSRSNGVTPGTQSSP 264
           D G+        Q   + ++ P  +  S G     +QEP P+  ++  ++ +    + +P
Sbjct: 166 DPGQG------DQQVCAEEADPELEPASGG-----EQEPRPQQAQTKAASQILENGEEAP 214

Query: 265 AP 266
            P
Sbjct: 215 GP 216



 Score = 38.9 bits (89), Expect = 0.017
 Identities = 17/36 (47%), Positives = 28/36 (77%)

Query: 8  INLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLK 43
          ++LSFL + E+E I GVL+RD  L+++E+ R+ KL+
Sbjct: 32 LDLSFLTEEEQEAIAGVLQRDARLRQLEEGRVSKLR 67


>gi|110227631 synaptotagmin-like 3 [Homo sapiens]
          Length = 542

 Score =  221 bits (563), Expect = 2e-57
 Identities = 144/387 (37%), Positives = 209/387 (54%), Gaps = 26/387 (6%)

Query: 344 RSKSVPGALDKDSLEETEESIDALVSSQLSTNTHR----LASGLSTTSLNSMMSVYSETG 399
           R  S P  L   + E+ + S + ++  Q   ++       + G    SL S+ S  +E G
Sbjct: 172 RKVSAPDILKPLNQEDPKCSTNPILKQQNLPSSPAPSTIFSGGFRHGSLISIDSTCTEMG 231

Query: 400 DYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNN 459
           ++ N  V+GEI   I YC+KT  L I +K C+NLA G+EKK++ + YVK+YLLPD+S   
Sbjct: 232 NFDNANVTGEIEFAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPYVKTYLLPDRSSQG 291

Query: 460 KRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWN 518
           KRKT ++  T +P F ETLKY ++  QL TR LQ+SVWH     R  FLGEV IP  +W+
Sbjct: 292 KRKTGVQRNTVDPTFQETLKYQVAPAQLVTRQLQVSVWHLGTLARRVFLGEVIIPLATWD 351

Query: 519 FENPTDE---WFVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKK 575
           FE+ T +   W  L+ K E   D   Q  GELTV  + + P       P +LQ     + 
Sbjct: 352 FEDSTTQSFRWHPLRAKAEKYEDSVPQSNGELTVRAKLVLPSR-----PRKLQ-----EA 401

Query: 576 GKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSV 635
            +  + P + G +  V +  AKNL  V+  GT +SFVKG L   D +  + K+ V++K  
Sbjct: 402 QEGTDQPSLHGQLCLV-VLGAKNL-PVRPDGTLNSFVKGCLTLPDQQKLRLKSPVLRKQA 459

Query: 636 NPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSN-IFLGGVRLNSGSGVSHGKNVDWM 694
            PQW H+F+FSG+ P  ++   LELT+WD+  F  N   LGG RL S    + G      
Sbjct: 460 CPQWKHSFVFSGVTPAQLRQSSLELTVWDQALFGMNDRLLGGTRLGSKGDTAVGG----- 514

Query: 695 DSQGEEQRLWQKMANNPGTPFEGVLML 721
           D+    +  WQK+ ++P    +  L+L
Sbjct: 515 DACSLSKLQWQKVLSSPNLWTDMTLVL 541



 Score =  102 bits (254), Expect = 1e-21
 Identities = 72/237 (30%), Positives = 110/237 (46%), Gaps = 27/237 (11%)

Query: 8   INLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTQ--QEASRVCV 65
           I+LS L + E+E IL VL RD+ ++  E++R RKLK  L   + +  K    +   + C 
Sbjct: 5   IDLSALKELEREAILQVLYRDQAVQNTEEERTRKLKTHLQHLRWKGAKNTDWEHKEKCCA 64

Query: 66  HCHRNLGLIFDRGDPCQACSLRVCRECRV-AGPNGSWKCTVCDKIAQLRIITGEWFFEEK 124
            C + LG +  RG  C+ CS RVC +CRV      +WKCTVC +   ++I TGEWF+EE+
Sbjct: 65  RCQQVLGFLLHRGAVCRGCSHRVCAQCRVFLRGTHAWKCTVCFEDRNVKIKTGEWFYEER 124

Query: 125 AKRF----KQVNVLG------------------TDVVRQSILRRSPGAEEVQSQ--EQTR 160
           AK+F    K   V G                     V +S   RSPG +       +   
Sbjct: 125 AKKFPTGGKHETVGGQLLQSYQKLSKISVVPPTPPPVSESQCSRSPGRKVSAPDILKPLN 184

Query: 161 QDAEKSDTSPVAGKKASHDGPKRKGFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQ 217
           Q+  K  T+P+  ++     P         FR  +   I +  T+ G   + ++ G+
Sbjct: 185 QEDPKCSTNPILKQQNLPSSPAPSTIFSGGFRHGSLISIDSTCTEMGNFDNANVTGE 241


>gi|92859638 synaptotagmin V [Homo sapiens]
          Length = 386

 Score =  129 bits (323), Expect = 1e-29
 Identities = 91/307 (29%), Positives = 136/307 (44%), Gaps = 49/307 (15%)

Query: 408 GEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRT 467
           G +   + Y +++G L + +     LA  D     +D YV+ YLLPDK R  + K   +T
Sbjct: 110 GRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGS-SDPYVRVYLLPDKRRRYETKVHRQT 168

Query: 468 GTNPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTDEWF 527
             NP F ET  + + + +L  R L ++V+ +DRF RN  +GEV +P  S +   P   W 
Sbjct: 169 -LNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWR 227

Query: 528 VLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISGG 587
            LQ     AP    +  G++   LRY+P                             + G
Sbjct: 228 ELQA----APREEQEKLGDICFSLRYVP-----------------------------TAG 254

Query: 588 ILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSG 647
            L V + EAKNL  +  GG SD +VK +LL    K  K KT + K ++NP +N  F F  
Sbjct: 255 KLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFE- 313

Query: 648 IHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQKM 707
           +    ++ V +ELT+ D +    N  +G V + + +G             G   R W  M
Sbjct: 314 VPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAG-------------GAGLRHWADM 360

Query: 708 ANNPGTP 714
             NP  P
Sbjct: 361 LANPRRP 367


>gi|211059429 synaptotagmin II [Homo sapiens]
          Length = 419

 Score =  124 bits (310), Expect = 4e-28
 Identities = 89/308 (28%), Positives = 146/308 (47%), Gaps = 51/308 (16%)

Query: 408 GEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRT 467
           G++   + Y ++   L + V     L   D     +D YVK +LLPDK +  K +TK+  
Sbjct: 141 GKLQFSLDYDFQANQLTVGVLQAAELPALD-MGGTSDPYVKVFLLPDKKK--KYETKVHR 197

Query: 468 GT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTDEW 526
            T NP FNET  + + + +L  +TL ++++ +DRF ++  +GEV++P ++ +   P +EW
Sbjct: 198 KTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEW 257

Query: 527 FVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISG 586
             LQ   +  P    +  G++   LRY+P                             + 
Sbjct: 258 RDLQGGEKEEP----EKLGDICTSLRYVP-----------------------------TA 284

Query: 587 GILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFS 646
           G L V I EAKNL  +  GG SD +VK +L+ +  +  K KT V KK++NP +N +F F 
Sbjct: 285 GKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFE 344

Query: 647 GIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQK 706
            I  + I+ V + +T+ D +    N  +G + + S             ++ G E R W  
Sbjct: 345 -IPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGS-------------NATGTELRHWSD 390

Query: 707 MANNPGTP 714
           M  NP  P
Sbjct: 391 MLANPRRP 398


>gi|31543670 synaptotagmin II [Homo sapiens]
          Length = 419

 Score =  124 bits (310), Expect = 4e-28
 Identities = 89/308 (28%), Positives = 146/308 (47%), Gaps = 51/308 (16%)

Query: 408 GEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRT 467
           G++   + Y ++   L + V     L   D     +D YVK +LLPDK +  K +TK+  
Sbjct: 141 GKLQFSLDYDFQANQLTVGVLQAAELPALD-MGGTSDPYVKVFLLPDKKK--KYETKVHR 197

Query: 468 GT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTDEW 526
            T NP FNET  + + + +L  +TL ++++ +DRF ++  +GEV++P ++ +   P +EW
Sbjct: 198 KTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEW 257

Query: 527 FVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISG 586
             LQ   +  P    +  G++   LRY+P                             + 
Sbjct: 258 RDLQGGEKEEP----EKLGDICTSLRYVP-----------------------------TA 284

Query: 587 GILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFS 646
           G L V I EAKNL  +  GG SD +VK +L+ +  +  K KT V KK++NP +N +F F 
Sbjct: 285 GKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFE 344

Query: 647 GIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQK 706
            I  + I+ V + +T+ D +    N  +G + + S             ++ G E R W  
Sbjct: 345 -IPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGS-------------NATGTELRHWSD 390

Query: 707 MANNPGTP 714
           M  NP  P
Sbjct: 391 MLANPRRP 398


>gi|6005997 double C2-like domains, beta [Homo sapiens]
          Length = 412

 Score =  117 bits (294), Expect = 3e-26
 Identities = 81/241 (33%), Positives = 120/241 (49%), Gaps = 36/241 (14%)

Query: 444 DAYVKSYLLPDKSRNNKRKTK-IRTGTNPEFNETLKYT-ISHTQLETRTLQLSVWHYDRF 501
           D YVK +LLP  S+ NK +TK +R   NP +NETL Y  I+   +  +TL++SV   D+F
Sbjct: 163 DPYVKLHLLPGASKANKLRTKTLRNTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKF 222

Query: 502 GRNSFLGEVEIPFDSWNFENPTDEWFVLQPK---VEFAPDIGLQYKGELTVVLRYIPPEE 558
             N F+GE  +P       N T  + +   K   V+   D  L+ +G + + L+Y   ++
Sbjct: 223 RHNEFIGETRVPLKKLK-PNHTKTFNICLEKQLPVDKTEDKSLEERGRILISLKYSSQKQ 281

Query: 559 NLMLPPEQLQGNKTFKKGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLP 618
            L+                             V I    +L A+ + G SD +VK YL P
Sbjct: 282 GLL-----------------------------VGIVRCAHLAAMDANGYSDPYVKTYLRP 312

Query: 619 DDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVR 678
           D  K +KHKT V KK++NP++N  F +  I   D+    LE+T+WD +   SN F+GGV 
Sbjct: 313 DVDKKSKHKTAVKKKTLNPEFNEEFCYE-IKHGDLAKKSLEVTVWDYDIGKSNDFIGGVV 371

Query: 679 L 679
           L
Sbjct: 372 L 372



 Score = 76.6 bits (187), Expect = 7e-14
 Identities = 41/104 (39%), Positives = 59/104 (56%), Gaps = 2/104 (1%)

Query: 408 GEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRT 467
           G IL+ + Y  +  GL + +  C +LA  D     +D YVK+YL PD  + +K KT ++ 
Sbjct: 268 GRILISLKYSSQKQGLLVGIVRCAHLAAMDANGY-SDPYVKTYLRPDVDKKSKHKTAVKK 326

Query: 468 GT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEV 510
            T NPEFNE   Y I H  L  ++L+++VW YD    N F+G V
Sbjct: 327 KTLNPEFNEEFCYEIKHGDLAKKSLEVTVWDYDIGKSNDFIGGV 370



 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 32/91 (35%), Positives = 52/91 (57%)

Query: 589 LEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSGI 648
           L   I +AK L  +   G +D +VK +LLP  SKA K +T  ++ ++NP WN T  + GI
Sbjct: 143 LHCTITKAKGLKPMDHNGLADPYVKLHLLPGASKANKLRTKTLRNTLNPTWNETLTYYGI 202

Query: 649 HPQDIKNVCLELTIWDKEAFSSNIFLGGVRL 679
             +D+    L +++ D++ F  N F+G  R+
Sbjct: 203 TDEDMIRKTLRISVCDEDKFRHNEFIGETRV 233


>gi|209447073 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  116 bits (291), Expect = 6e-26
 Identities = 86/308 (27%), Positives = 144/308 (46%), Gaps = 51/308 (16%)

Query: 408 GEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRT 467
           G++   + Y ++   L + +     L   D     +D YVK +LLPDK +  K +TK+  
Sbjct: 144 GKLQYSLDYDFQNNQLLVGIIQAAELPALD-MGGTSDPYVKVFLLPDKKK--KFETKVHR 200

Query: 468 GT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTDEW 526
            T NP FNE   + + +++L  +TL ++V+ +DRF ++  +GE ++P ++ +F + T+EW
Sbjct: 201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEW 260

Query: 527 FVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISG 586
             LQ     A     +  G++   LRY+P                             + 
Sbjct: 261 RDLQS----AEKEEQEKLGDICFSLRYVP-----------------------------TA 287

Query: 587 GILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFS 646
           G L V I EAKNL  +  GG SD +VK +L+ +  +  K KT + K ++NP +N +F F 
Sbjct: 288 GKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFE 347

Query: 647 GIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQK 706
            +  + I+ V + +T+ D +    N  +G V +               +S G E R W  
Sbjct: 348 -VPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVG-------------YNSTGAELRHWSD 393

Query: 707 MANNPGTP 714
           M  NP  P
Sbjct: 394 MLANPRRP 401


>gi|5032139 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  116 bits (291), Expect = 6e-26
 Identities = 86/308 (27%), Positives = 144/308 (46%), Gaps = 51/308 (16%)

Query: 408 GEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRT 467
           G++   + Y ++   L + +     L   D     +D YVK +LLPDK +  K +TK+  
Sbjct: 144 GKLQYSLDYDFQNNQLLVGIIQAAELPALD-MGGTSDPYVKVFLLPDKKK--KFETKVHR 200

Query: 468 GT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTDEW 526
            T NP FNE   + + +++L  +TL ++V+ +DRF ++  +GE ++P ++ +F + T+EW
Sbjct: 201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEW 260

Query: 527 FVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISG 586
             LQ     A     +  G++   LRY+P                             + 
Sbjct: 261 RDLQS----AEKEEQEKLGDICFSLRYVP-----------------------------TA 287

Query: 587 GILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFS 646
           G L V I EAKNL  +  GG SD +VK +L+ +  +  K KT + K ++NP +N +F F 
Sbjct: 288 GKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFE 347

Query: 647 GIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQK 706
            +  + I+ V + +T+ D +    N  +G V +               +S G E R W  
Sbjct: 348 -VPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVG-------------YNSTGAELRHWSD 393

Query: 707 MANNPGTP 714
           M  NP  P
Sbjct: 394 MLANPRRP 401


>gi|209447070 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  116 bits (291), Expect = 6e-26
 Identities = 86/308 (27%), Positives = 144/308 (46%), Gaps = 51/308 (16%)

Query: 408 GEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRT 467
           G++   + Y ++   L + +     L   D     +D YVK +LLPDK +  K +TK+  
Sbjct: 144 GKLQYSLDYDFQNNQLLVGIIQAAELPALD-MGGTSDPYVKVFLLPDKKK--KFETKVHR 200

Query: 468 GT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTDEW 526
            T NP FNE   + + +++L  +TL ++V+ +DRF ++  +GE ++P ++ +F + T+EW
Sbjct: 201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEW 260

Query: 527 FVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISG 586
             LQ     A     +  G++   LRY+P                             + 
Sbjct: 261 RDLQS----AEKEEQEKLGDICFSLRYVP-----------------------------TA 287

Query: 587 GILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFS 646
           G L V I EAKNL  +  GG SD +VK +L+ +  +  K KT + K ++NP +N +F F 
Sbjct: 288 GKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFE 347

Query: 647 GIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQK 706
            +  + I+ V + +T+ D +    N  +G V +               +S G E R W  
Sbjct: 348 -VPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVG-------------YNSTGAELRHWSD 393

Query: 707 MANNPGTP 714
           M  NP  P
Sbjct: 394 MLANPRRP 401


>gi|38570146 synaptotagmin VII [Homo sapiens]
          Length = 403

 Score =  112 bits (281), Expect = 9e-25
 Identities = 98/355 (27%), Positives = 155/355 (43%), Gaps = 48/355 (13%)

Query: 342 SIRSKSVPGALDKDSLEETEESIDALVSSQLSTNTHRLASGLSTTSLNSMMSVYSETGDY 401
           ++ +  VPG    D  +   E       S +S   + L S +   S  S      E    
Sbjct: 79  AVNTAPVPGQTPHDESDRRTEP-----RSSVSDLVNSLTSEMLMLSPGSEEDEAHEGCSR 133

Query: 402 GNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKR 461
            N+   G I   + Y ++   L + +   + L   D     +D +VK YLLPDK    + 
Sbjct: 134 ENL---GRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGT-SDPFVKIYLLPDKKHKLET 189

Query: 462 KTKIRTGTNPEFNETLKYT-ISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFE 520
           K K R   NP +NET  +    + ++  R L L V  YDRF RN  +GEV IP +  +  
Sbjct: 190 KVK-RKNLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIPLNKVDLT 248

Query: 521 NPTDEWFVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKE 580
                W  L+P  +     G   +GEL + L Y P   +++                   
Sbjct: 249 QMQTFWKDLKPCSD-----GSGSRGELLLSLCYNPSANSII------------------- 284

Query: 581 SPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWN 640
                     V I +A+NL A+  GGTSD +VK +L+  D +  K KT+ +K+++NP +N
Sbjct: 285 ----------VNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTMKRNLNPIFN 334

Query: 641 HTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMD 695
            +F F  I  + ++   + +T+ DK+  S N  +G + L+  SG    K+  W D
Sbjct: 335 ESFAFD-IPTEKLRETTIIITVMDKDKLSRNDVIGKIYLSWKSGPGEVKH--WKD 386


>gi|47078261 double C2-like domains, alpha [Homo sapiens]
          Length = 400

 Score =  108 bits (271), Expect = 1e-23
 Identities = 87/278 (31%), Positives = 129/278 (46%), Gaps = 27/278 (9%)

Query: 444 DAYVKSYLLPDKSRNNKRKTKIRTGT-NPEFNETLKYT-ISHTQLETRTLQLSVWHYDRF 501
           D YVK +LLP   + NK KTK +  T NP +NE L Y+ I+   +  + L+++V   D+ 
Sbjct: 126 DPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKL 185

Query: 502 GRNSFLGEVEIPFDSWNFENPTDEWFVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLM 561
             N F+GE+ +P               L+ +V  A          ++  LR I      +
Sbjct: 186 SHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLASP------SSMSAALRGISCYLKEL 239

Query: 562 LPPEQLQGNKTFKKGKKKESPVISG---GILEVFIKEAKNLTAVKSGGTSDSFVKGYLLP 618
              EQ QG    ++G+   S   S    G+L V I    +L A+   G SD +VK YL P
Sbjct: 240 EQAEQGQGLLE-ERGRILLSLSYSSRRRGLL-VGILRCAHLAAMDVNGYSDPYVKTYLRP 297

Query: 619 DDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVR 678
           D  K +KHKT V KK++NP++N  F +  I    +    LE+T+WD +   SN F+GGV 
Sbjct: 298 DVDKKSKHKTCVKKKTLNPEFNEEFFYE-IELSTLATKTLEVTVWDYDIGKSNDFIGGVS 356

Query: 679 LNSGSGVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFE 716
           L  G             ++GE ++ W      P    E
Sbjct: 357 LGPG-------------ARGEARKHWSDCLQQPDAALE 381



 Score = 80.1 bits (196), Expect = 7e-15
 Identities = 45/112 (40%), Positives = 65/112 (58%), Gaps = 2/112 (1%)

Query: 402 GNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKR 461
           G ++  G ILL +SY  +  GL + +  C +LA  D     +D YVK+YL PD  + +K 
Sbjct: 247 GLLEERGRILLSLSYSSRRRGLLVGILRCAHLAAMDVNGY-SDPYVKTYLRPDVDKKSKH 305

Query: 462 KTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEI 512
           KT ++  T NPEFNE   Y I  + L T+TL+++VW YD    N F+G V +
Sbjct: 306 KTCVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSL 357



 Score = 63.5 bits (153), Expect = 6e-10
 Identities = 33/91 (36%), Positives = 49/91 (53%)

Query: 589 LEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSGI 648
           L   I  AK L  +   G +D +VK +LLP   KA K KT   + ++NP WN    +SGI
Sbjct: 106 LHCSILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGI 165

Query: 649 HPQDIKNVCLELTIWDKEAFSSNIFLGGVRL 679
              DI +  L + + D++  S N F+G +R+
Sbjct: 166 TDDDITHKVLRIAVCDEDKLSHNEFIGEIRV 196


>gi|238550198 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  108 bits (269), Expect = 2e-23
 Identities = 89/322 (27%), Positives = 137/322 (42%), Gaps = 53/322 (16%)

Query: 398 TGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSR 457
           +G+ G     G I   + Y Y +  L + +    +L   D     +D YVK YLLPD  R
Sbjct: 291 SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGF-SDPYVKIYLLPD--R 347

Query: 458 NNKRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDS 516
             K +TK+   T NP FNET ++++   +L  R L  SV+ +DRF R+  +G+V +    
Sbjct: 348 KKKFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLL 407

Query: 517 WNFENPTDE--WFVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFK 574
              E P D   W  +        D+     GEL   L Y+P                   
Sbjct: 408 ELAEQPPDRPLWRDIVEGGSEKADL-----GELNFSLCYLP------------------- 443

Query: 575 KGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKS 634
                     + G L V I +A NL A+   G SD +VK  L+ +  +  K KT + K +
Sbjct: 444 ----------TAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNT 493

Query: 635 VNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWM 694
           +NP +N   +F  + P+ ++NV L + + D +    N  +G  R+   +   HG+     
Sbjct: 494 LNPTYNEALVFD-VAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGR----- 547

Query: 695 DSQGEEQRLWQKMANNPGTPFE 716
                    W +M  NP  P E
Sbjct: 548 -------EHWAEMLANPRKPVE 562


>gi|238550196 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  108 bits (269), Expect = 2e-23
 Identities = 89/322 (27%), Positives = 137/322 (42%), Gaps = 53/322 (16%)

Query: 398 TGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSR 457
           +G+ G     G I   + Y Y +  L + +    +L   D     +D YVK YLLPD  R
Sbjct: 291 SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGF-SDPYVKIYLLPD--R 347

Query: 458 NNKRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDS 516
             K +TK+   T NP FNET ++++   +L  R L  SV+ +DRF R+  +G+V +    
Sbjct: 348 KKKFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLL 407

Query: 517 WNFENPTDE--WFVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFK 574
              E P D   W  +        D+     GEL   L Y+P                   
Sbjct: 408 ELAEQPPDRPLWRDIVEGGSEKADL-----GELNFSLCYLP------------------- 443

Query: 575 KGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKS 634
                     + G L V I +A NL A+   G SD +VK  L+ +  +  K KT + K +
Sbjct: 444 ----------TAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNT 493

Query: 635 VNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWM 694
           +NP +N   +F  + P+ ++NV L + + D +    N  +G  R+   +   HG+     
Sbjct: 494 LNPTYNEALVFD-VAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGR----- 547

Query: 695 DSQGEEQRLWQKMANNPGTPFE 716
                    W +M  NP  P E
Sbjct: 548 -------EHWAEMLANPRKPVE 562


>gi|14150054 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  108 bits (269), Expect = 2e-23
 Identities = 89/322 (27%), Positives = 137/322 (42%), Gaps = 53/322 (16%)

Query: 398 TGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSR 457
           +G+ G     G I   + Y Y +  L + +    +L   D     +D YVK YLLPD  R
Sbjct: 291 SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGF-SDPYVKIYLLPD--R 347

Query: 458 NNKRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDS 516
             K +TK+   T NP FNET ++++   +L  R L  SV+ +DRF R+  +G+V +    
Sbjct: 348 KKKFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLL 407

Query: 517 WNFENPTDE--WFVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFK 574
              E P D   W  +        D+     GEL   L Y+P                   
Sbjct: 408 ELAEQPPDRPLWRDIVEGGSEKADL-----GELNFSLCYLP------------------- 443

Query: 575 KGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKS 634
                     + G L V I +A NL A+   G SD +VK  L+ +  +  K KT + K +
Sbjct: 444 ----------TAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNT 493

Query: 635 VNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWM 694
           +NP +N   +F  + P+ ++NV L + + D +    N  +G  R+   +   HG+     
Sbjct: 494 LNPTYNEALVFD-VAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGR----- 547

Query: 695 DSQGEEQRLWQKMANNPGTPFE 716
                    W +M  NP  P E
Sbjct: 548 -------EHWAEMLANPRKPVE 562


>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
          Length = 694

 Score =  105 bits (262), Expect = 1e-22
 Identities = 86/278 (30%), Positives = 136/278 (48%), Gaps = 31/278 (11%)

Query: 444 DAYVKSYLLPDKSRNNKRKTK-IRTGTNPEFNETLKYT-ISHTQLETRTLQLSVWHYDRF 501
           D YVK +LLP  S++NK +TK +R   NP +NETL Y  I+   ++ +TL++SV   D+F
Sbjct: 429 DPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKF 488

Query: 502 GRNSFLGEVEIPFDSWNFENPTDEWFVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLM 561
           G N F+GE           N    + +   +V     I ++  G           EE  +
Sbjct: 489 GHNEFIGETRFSLKKLK-PNQRKNFNICLERV-----IPMKRAGTTGSARGMALYEEEQV 542

Query: 562 LPPEQLQGNKTFKKGKKKESPVIS---GGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLP 618
                ++     ++GK   S + S   GG++ V I    +L A+ + G SD FVK +L P
Sbjct: 543 ERVGDIE-----ERGKILVSLMYSTQQGGLI-VGIIRCVHLAAMDANGYSDPFVKLWLKP 596

Query: 619 DDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVR 678
           D  K  KHKT + KK++NP++N  F F  I   D+    L++++WD +   SN ++GG +
Sbjct: 597 DMGKKAKHKTQIKKKTLNPEFNEEF-FYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQ 655

Query: 679 LNSGSGVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFE 716
           L    G+S         ++GE  + W +   N     E
Sbjct: 656 L----GIS---------AKGERLKHWYECLKNKDKKIE 680



 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 46/131 (35%), Positives = 72/131 (54%), Gaps = 4/131 (3%)

Query: 385 TTSLNSMMSVYSE--TGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQR 442
           TT     M++Y E      G+++  G+IL+ + Y  + GGL + +  C +LA  D     
Sbjct: 527 TTGSARGMALYEEEQVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGY- 585

Query: 443 TDAYVKSYLLPDKSRNNKRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRF 501
           +D +VK +L PD  +  K KT+I+  T NPEFNE   Y I H+ L  ++L +SVW YD  
Sbjct: 586 SDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIG 645

Query: 502 GRNSFLGEVEI 512
             N ++G  ++
Sbjct: 646 KSNDYIGGCQL 656



 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 32/92 (34%), Positives = 55/92 (59%)

Query: 589 LEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSGI 648
           L+  I +AK L  + S G +D +VK +LLP  SK+ K +T  ++ + NP WN T ++ GI
Sbjct: 409 LQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGI 468

Query: 649 HPQDIKNVCLELTIWDKEAFSSNIFLGGVRLN 680
             +D++   L +++ D++ F  N F+G  R +
Sbjct: 469 TDEDMQRKTLRISVCDEDKFGHNEFIGETRFS 500



 Score = 63.2 bits (152), Expect = 8e-10
 Identities = 66/275 (24%), Positives = 109/275 (39%), Gaps = 33/275 (12%)

Query: 13  LLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTQQEASRVCVHCHRNLG 72
           L D EKE+I  V+ R E ++++E +RI +L + L   ++       +    C+ C   LG
Sbjct: 50  LTDEEKEIINRVIARAEKMEEMEQERIGRLVDRLENMRK---NVAGDGVNRCILCGEQLG 106

Query: 73  LIFDRGDPCQACSLRVCRECRVAGPN---GSWKCTVCDKIAQLRIITGEWFFEEKAKRFK 129
           ++      C+ C   VC +C V   N     W C +C +  ++   +G WFF+   K+  
Sbjct: 107 MLGSACVVCEDCKKNVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQ-- 164

Query: 130 QVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAEKSDTSPVAGKKASHDGPKRK----- 184
              VL   +  +    + P   E  + EQ   + +    +P  G      GP +K     
Sbjct: 165 ---VLPQPMPIKKTKPQQP-VSEPAAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDP 220

Query: 185 ------GFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDL 238
                 G      R A+   + +   D   S S D  G    S +SP G  R ++  +  
Sbjct: 221 ASAPGRGNYGPPVRRASEARMSSSSRD---SESWDHSGGAGDSSRSPAGLRRANSVQASR 277

Query: 239 ----NDQEPGPRTPKSSRSNGVTPGTQSSPAPSTR 269
               + Q P P  P      G   G++  P P+ R
Sbjct: 278 PAPGSVQSPAPPQPGQP---GTPGGSRPGPGPAGR 309


>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
          Length = 690

 Score =  105 bits (262), Expect = 1e-22
 Identities = 86/278 (30%), Positives = 136/278 (48%), Gaps = 31/278 (11%)

Query: 444 DAYVKSYLLPDKSRNNKRKTK-IRTGTNPEFNETLKYT-ISHTQLETRTLQLSVWHYDRF 501
           D YVK +LLP  S++NK +TK +R   NP +NETL Y  I+   ++ +TL++SV   D+F
Sbjct: 425 DPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKF 484

Query: 502 GRNSFLGEVEIPFDSWNFENPTDEWFVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLM 561
           G N F+GE           N    + +   +V     I ++  G           EE  +
Sbjct: 485 GHNEFIGETRFSLKKLK-PNQRKNFNICLERV-----IPMKRAGTTGSARGMALYEEEQV 538

Query: 562 LPPEQLQGNKTFKKGKKKESPVIS---GGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLP 618
                ++     ++GK   S + S   GG++ V I    +L A+ + G SD FVK +L P
Sbjct: 539 ERVGDIE-----ERGKILVSLMYSTQQGGLI-VGIIRCVHLAAMDANGYSDPFVKLWLKP 592

Query: 619 DDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVR 678
           D  K  KHKT + KK++NP++N  F F  I   D+    L++++WD +   SN ++GG +
Sbjct: 593 DMGKKAKHKTQIKKKTLNPEFNEEF-FYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQ 651

Query: 679 LNSGSGVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFE 716
           L    G+S         ++GE  + W +   N     E
Sbjct: 652 L----GIS---------AKGERLKHWYECLKNKDKKIE 676



 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 46/131 (35%), Positives = 72/131 (54%), Gaps = 4/131 (3%)

Query: 385 TTSLNSMMSVYSE--TGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQR 442
           TT     M++Y E      G+++  G+IL+ + Y  + GGL + +  C +LA  D     
Sbjct: 523 TTGSARGMALYEEEQVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGY- 581

Query: 443 TDAYVKSYLLPDKSRNNKRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRF 501
           +D +VK +L PD  +  K KT+I+  T NPEFNE   Y I H+ L  ++L +SVW YD  
Sbjct: 582 SDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIG 641

Query: 502 GRNSFLGEVEI 512
             N ++G  ++
Sbjct: 642 KSNDYIGGCQL 652



 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 32/92 (34%), Positives = 55/92 (59%)

Query: 589 LEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSGI 648
           L+  I +AK L  + S G +D +VK +LLP  SK+ K +T  ++ + NP WN T ++ GI
Sbjct: 405 LQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGI 464

Query: 649 HPQDIKNVCLELTIWDKEAFSSNIFLGGVRLN 680
             +D++   L +++ D++ F  N F+G  R +
Sbjct: 465 TDEDMQRKTLRISVCDEDKFGHNEFIGETRFS 496



 Score = 63.2 bits (152), Expect = 8e-10
 Identities = 66/275 (24%), Positives = 109/275 (39%), Gaps = 33/275 (12%)

Query: 13  LLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTQQEASRVCVHCHRNLG 72
           L D EKE+I  V+ R E ++++E +RI +L + L   ++       +    C+ C   LG
Sbjct: 46  LTDEEKEIINRVIARAEKMEEMEQERIGRLVDRLENMRK---NVAGDGVNRCILCGEQLG 102

Query: 73  LIFDRGDPCQACSLRVCRECRVAGPN---GSWKCTVCDKIAQLRIITGEWFFEEKAKRFK 129
           ++      C+ C   VC +C V   N     W C +C +  ++   +G WFF+   K+  
Sbjct: 103 MLGSACVVCEDCKKNVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQ-- 160

Query: 130 QVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAEKSDTSPVAGKKASHDGPKRK----- 184
              VL   +  +    + P   E  + EQ   + +    +P  G      GP +K     
Sbjct: 161 ---VLPQPMPIKKTKPQQP-VSEPAAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDP 216

Query: 185 ------GFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDL 238
                 G      R A+   + +   D   S S D  G    S +SP G  R ++  +  
Sbjct: 217 ASAPGRGNYGPPVRRASEARMSSSSRD---SESWDHSGGAGDSSRSPAGLRRANSVQASR 273

Query: 239 ----NDQEPGPRTPKSSRSNGVTPGTQSSPAPSTR 269
               + Q P P  P      G   G++  P P+ R
Sbjct: 274 PAPGSVQSPAPPQPGQP---GTPGGSRPGPGPAGR 305


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.130    0.377 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,958,719
Number of Sequences: 37866
Number of extensions: 1402545
Number of successful extensions: 5941
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 103
Number of HSP's successfully gapped in prelim test: 205
Number of HSP's that attempted gapping in prelim test: 5063
Number of HSP's gapped (non-prelim): 887
length of query: 730
length of database: 18,247,518
effective HSP length: 110
effective length of query: 620
effective length of database: 14,082,258
effective search space: 8730999960
effective search space used: 8730999960
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.