Search of human proteins with 254039648

Search of human proteins with 254039648

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens]
         (752 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens]           1511   0.0  
gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens]           1453   0.0  
gi|20270305 synaptotagmin-like 5 isoform 1 [Homo sapiens]            1453   0.0  
gi|193804862 synaptotagmin-like 4 [Homo sapiens]                      489   e-138
gi|193804860 synaptotagmin-like 4 [Homo sapiens]                      489   e-138
gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens]            270   5e-72
gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens]            270   5e-72
gi|46255064 synaptotagmin-like 2 isoform d [Homo sapiens]             258   1e-68
gi|46255062 synaptotagmin-like 2 isoform c [Homo sapiens]             258   1e-68
gi|15011900 synaptotagmin-like 2 isoform b [Homo sapiens]             257   2e-68
gi|46255066 synaptotagmin-like 2 isoform e [Homo sapiens]             257   2e-68
gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens]             256   5e-68
gi|46255068 synaptotagmin-like 2 isoform f [Homo sapiens]             252   1e-66
gi|244790016 synaptotagmin-like 2 isoform h [Homo sapiens]            251   1e-66
gi|14249614 synaptotagmin-like 1 [Homo sapiens]                       232   1e-60
gi|110227631 synaptotagmin-like 3 [Homo sapiens]                      220   4e-57
gi|92859638 synaptotagmin V [Homo sapiens]                            129   1e-29
gi|211059429 synaptotagmin II [Homo sapiens]                          124   4e-28
gi|31543670 synaptotagmin II [Homo sapiens]                           124   4e-28
gi|6005997 double C2-like domains, beta [Homo sapiens]                117   3e-26
gi|209447073 synaptotagmin I [Homo sapiens]                           116   7e-26
gi|5032139 synaptotagmin I [Homo sapiens]                             116   7e-26
gi|209447070 synaptotagmin I [Homo sapiens]                           116   7e-26
gi|38570146 synaptotagmin VII [Homo sapiens]                          112   1e-24
gi|47078261 double C2-like domains, alpha [Homo sapiens]              108   1e-23
gi|238550198 synaptotagmin III [Homo sapiens]                         108   2e-23
gi|238550196 synaptotagmin III [Homo sapiens]                         108   2e-23
gi|14150054 synaptotagmin III [Homo sapiens]                          108   2e-23
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]            105   2e-22
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]             105   2e-22

>gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens]
          Length = 752

 Score = 1511 bits (3913), Expect = 0.0
 Identities = 752/752 (100%), Positives = 752/752 (100%)

Query: 1   MSKNSEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTQQEA 60
           MSKNSEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTQQEA
Sbjct: 1   MSKNSEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTQQEA 60

Query: 61  SRVCVHCHRNLGLIFDRGDPCQACSLRVCRECRVAGPNGSWKCTVCDKIAQLRIITGEWF 120
           SRVCVHCHRNLGLIFDRGDPCQACSLRVCRECRVAGPNGSWKCTVCDKIAQLRIITGEWF
Sbjct: 61  SRVCVHCHRNLGLIFDRGDPCQACSLRVCRECRVAGPNGSWKCTVCDKIAQLRIITGEWF 120

Query: 121 FEEKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAEKSDTSPVAGKKASHDG 180
           FEEKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAEKSDTSPVAGKKASHDG
Sbjct: 121 FEEKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAEKSDTSPVAGKKASHDG 180

Query: 181 PKRKGFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLND 240
           PKRKGFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLND
Sbjct: 181 PKRKGFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLND 240

Query: 241 QEPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKS 300
           QEPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKS
Sbjct: 241 QEPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKS 300

Query: 301 HRRNTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVSIRSKSVPGALDKDSLEET 360
           HRRNTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVSIRSKSVPGALDKDSLEET
Sbjct: 301 HRRNTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVSIRSKSVPGALDKDSLEET 360

Query: 361 EESIDALVSSQLSTNTHRLASGLSTSSQAGSDRKWTYLNVPDADSDTTSLNSMMSVYSET 420
           EESIDALVSSQLSTNTHRLASGLSTSSQAGSDRKWTYLNVPDADSDTTSLNSMMSVYSET
Sbjct: 361 EESIDALVSSQLSTNTHRLASGLSTSSQAGSDRKWTYLNVPDADSDTTSLNSMMSVYSET 420

Query: 421 GDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRN 480
           GDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRN
Sbjct: 421 GDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRN 480

Query: 481 NKRKTKIRTGTNPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWN 540
           NKRKTKIRTGTNPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWN
Sbjct: 481 NKRKTKIRTGTNPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWN 540

Query: 541 FENPTDEWFVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKK 600
           FENPTDEWFVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKK
Sbjct: 541 FENPTDEWFVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKK 600

Query: 601 KESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQ 660
           KESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQ
Sbjct: 601 KESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQ 660

Query: 661 WNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQG 720
           WNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQG
Sbjct: 661 WNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQG 720

Query: 721 EEQRLWQKMANNPGTPFEGVLMLRSSMGKCRL 752
           EEQRLWQKMANNPGTPFEGVLMLRSSMGKCRL
Sbjct: 721 EEQRLWQKMANNPGTPFEGVLMLRSSMGKCRL 752


>gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens]
          Length = 730

 Score = 1453 bits (3762), Expect = 0.0
 Identities = 730/752 (97%), Positives = 730/752 (97%), Gaps = 22/752 (2%)

Query: 1   MSKNSEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTQQEA 60
           MSKNSEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTQQEA
Sbjct: 1   MSKNSEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTQQEA 60

Query: 61  SRVCVHCHRNLGLIFDRGDPCQACSLRVCRECRVAGPNGSWKCTVCDKIAQLRIITGEWF 120
           SRVCVHCHRNLGLIFDRGDPCQACSLRVCRECRVAGPNGSWKCTVCDKIAQLRIITGEWF
Sbjct: 61  SRVCVHCHRNLGLIFDRGDPCQACSLRVCRECRVAGPNGSWKCTVCDKIAQLRIITGEWF 120

Query: 121 FEEKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAEKSDTSPVAGKKASHDG 180
           FEEKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAEKSDTSPVAGKKASHDG
Sbjct: 121 FEEKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAEKSDTSPVAGKKASHDG 180

Query: 181 PKRKGFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLND 240
           PKRKGFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLND
Sbjct: 181 PKRKGFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLND 240

Query: 241 QEPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKS 300
           QEPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKS
Sbjct: 241 QEPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKS 300

Query: 301 HRRNTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVSIRSKSVPGALDKDSLEET 360
           HRRNTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVSIRSKSVPGALDKDSLEET
Sbjct: 301 HRRNTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVSIRSKSVPGALDKDSLEET 360

Query: 361 EESIDALVSSQLSTNTHRLASGLSTSSQAGSDRKWTYLNVPDADSDTTSLNSMMSVYSET 420
           EESIDALVSSQLSTNTHRLASGLS                      TTSLNSMMSVYSET
Sbjct: 361 EESIDALVSSQLSTNTHRLASGLS----------------------TTSLNSMMSVYSET 398

Query: 421 GDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRN 480
           GDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRN
Sbjct: 399 GDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRN 458

Query: 481 NKRKTKIRTGTNPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWN 540
           NKRKTKIRTGTNPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWN
Sbjct: 459 NKRKTKIRTGTNPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWN 518

Query: 541 FENPTDEWFVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKK 600
           FENPTDEWFVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKK
Sbjct: 519 FENPTDEWFVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKK 578

Query: 601 KESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQ 660
           KESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQ
Sbjct: 579 KESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQ 638

Query: 661 WNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQG 720
           WNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQG
Sbjct: 639 WNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQG 698

Query: 721 EEQRLWQKMANNPGTPFEGVLMLRSSMGKCRL 752
           EEQRLWQKMANNPGTPFEGVLMLRSSMGKCRL
Sbjct: 699 EEQRLWQKMANNPGTPFEGVLMLRSSMGKCRL 730


>gi|20270305 synaptotagmin-like 5 isoform 1 [Homo sapiens]
          Length = 730

 Score = 1453 bits (3762), Expect = 0.0
 Identities = 730/752 (97%), Positives = 730/752 (97%), Gaps = 22/752 (2%)

Query: 1   MSKNSEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTQQEA 60
           MSKNSEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTQQEA
Sbjct: 1   MSKNSEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTQQEA 60

Query: 61  SRVCVHCHRNLGLIFDRGDPCQACSLRVCRECRVAGPNGSWKCTVCDKIAQLRIITGEWF 120
           SRVCVHCHRNLGLIFDRGDPCQACSLRVCRECRVAGPNGSWKCTVCDKIAQLRIITGEWF
Sbjct: 61  SRVCVHCHRNLGLIFDRGDPCQACSLRVCRECRVAGPNGSWKCTVCDKIAQLRIITGEWF 120

Query: 121 FEEKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAEKSDTSPVAGKKASHDG 180
           FEEKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAEKSDTSPVAGKKASHDG
Sbjct: 121 FEEKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAEKSDTSPVAGKKASHDG 180

Query: 181 PKRKGFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLND 240
           PKRKGFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLND
Sbjct: 181 PKRKGFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLND 240

Query: 241 QEPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKS 300
           QEPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKS
Sbjct: 241 QEPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKS 300

Query: 301 HRRNTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVSIRSKSVPGALDKDSLEET 360
           HRRNTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVSIRSKSVPGALDKDSLEET
Sbjct: 301 HRRNTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVSIRSKSVPGALDKDSLEET 360

Query: 361 EESIDALVSSQLSTNTHRLASGLSTSSQAGSDRKWTYLNVPDADSDTTSLNSMMSVYSET 420
           EESIDALVSSQLSTNTHRLASGLS                      TTSLNSMMSVYSET
Sbjct: 361 EESIDALVSSQLSTNTHRLASGLS----------------------TTSLNSMMSVYSET 398

Query: 421 GDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRN 480
           GDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRN
Sbjct: 399 GDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRN 458

Query: 481 NKRKTKIRTGTNPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWN 540
           NKRKTKIRTGTNPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWN
Sbjct: 459 NKRKTKIRTGTNPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWN 518

Query: 541 FENPTDEWFVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKK 600
           FENPTDEWFVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKK
Sbjct: 519 FENPTDEWFVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKK 578

Query: 601 KESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQ 660
           KESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQ
Sbjct: 579 KESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQ 638

Query: 661 WNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQG 720
           WNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQG
Sbjct: 639 WNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQG 698

Query: 721 EEQRLWQKMANNPGTPFEGVLMLRSSMGKCRL 752
           EEQRLWQKMANNPGTPFEGVLMLRSSMGKCRL
Sbjct: 699 EEQRLWQKMANNPGTPFEGVLMLRSSMGKCRL 730


>gi|193804862 synaptotagmin-like 4 [Homo sapiens]
          Length = 671

 Score =  489 bits (1258), Expect = e-138
 Identities = 300/753 (39%), Positives = 423/753 (56%), Gaps = 90/753 (11%)

Query: 5   SEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGK--TQQEASR 62
           SE ++LSFL + EK++IL VL+RDE ++K ++KRIR+LKNELLE KR+  K  +Q  + R
Sbjct: 2   SELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSDR 61

Query: 63  VCVHCHRNLGLIFDRGDPCQACSLRVCRECRVAGPNGSWKCTVCDKIAQLRIITGEWFFE 122
            C  C  +LG +  + + C+ C+  VCR+CR+   NG+W+C VC K  +L+  TG+WF++
Sbjct: 62  TCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFYD 121

Query: 123 EKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQTR-QDAEKSDTSPVAGKKASHDGP 181
           +K  RF      G++++R S LR  P   + ++  Q+     +  D  P  G+K   +  
Sbjct: 122 QKVNRFAYRT--GSEIIRMS-LRHKPAVSKRETVGQSLLHQTQMGDIWP--GRKIIQERQ 176

Query: 182 KRKGFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLNDQ 241
           K    L              PK  +G+S +L+ + +   S  +    D  ST   D  D+
Sbjct: 177 KEPSVLFE-----------VPKLKSGKS-ALEAESESLDSFTA----DSDSTSRRDSLDK 220

Query: 242 EPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKSH 301
                       +G+ P  +   AP ++        + G +N + +   E   ++ T+  
Sbjct: 221 ------------SGLFPEWKKMSAPKSQVEKET---QPGGQNVVFVDEGEMIFKKNTRKI 265

Query: 302 RRNTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVSIRSKSVPGALDKDSLEETE 361
            R                S+ ++S +DL          ++  RSKSVPG       EE E
Sbjct: 266 LR---------------PSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGLNVDMEEEEEE 310

Query: 362 ESIDALVSSQLSTNTHRLASGLSTSSQAGSDRKWTYLNVPDADSDTTSLNSMMSVYSETG 421
           E ID LV        HR     S S Q+GS                +++ SMMS+YSE G
Sbjct: 311 EDIDHLVK------LHRQKLARS-SMQSGSSM--------------STIGSMMSIYSEAG 349

Query: 422 DYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNN 481
           D+GN+ V+G I   + Y  +T  L + VK C  LA  DE K+R++ YVK+YLLPDKSR  
Sbjct: 350 DFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQG 409

Query: 482 KRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWN 540
           KRKT I+  T NP ++ETL+Y I  + L  RTLQ SVWH+ RFGRN+FLGE EI  DSW 
Sbjct: 410 KRKTSIKRDTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWK 469

Query: 541 FENPTDEWFVLQPKVEFAPDIGL-QYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGK 599
            +   D    L  K+      GL  +KGEL V L+YIP              +KT   G 
Sbjct: 470 LDKKLDHCLPLHGKISAESPTGLPSHKGELVVSLKYIP-------------ASKTPVGGD 516

Query: 600 KKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNP 659
           +K+S    GG L+V+IKEAKNLTA K+GGTSDSFVKGYLLP  +KA+K KT V+KK++NP
Sbjct: 517 RKKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNP 576

Query: 660 QWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQ 719
            +NHTF+++G+  +D++++CLELT+WD+E  +SN FLGGVRL  G+G+S+G+ VDWMDS 
Sbjct: 577 HYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDST 636

Query: 720 GEEQRLWQKMANNPGTPFEGVLMLRSSMGKCRL 752
           GEE  LWQKM   PG+  EG L LRSSM K +L
Sbjct: 637 GEEVSLWQKMRQYPGSWAEGTLQLRSSMAKQKL 669


>gi|193804860 synaptotagmin-like 4 [Homo sapiens]
          Length = 671

 Score =  489 bits (1258), Expect = e-138
 Identities = 300/753 (39%), Positives = 423/753 (56%), Gaps = 90/753 (11%)

Query: 5   SEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGK--TQQEASR 62
           SE ++LSFL + EK++IL VL+RDE ++K ++KRIR+LKNELLE KR+  K  +Q  + R
Sbjct: 2   SELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSDR 61

Query: 63  VCVHCHRNLGLIFDRGDPCQACSLRVCRECRVAGPNGSWKCTVCDKIAQLRIITGEWFFE 122
            C  C  +LG +  + + C+ C+  VCR+CR+   NG+W+C VC K  +L+  TG+WF++
Sbjct: 62  TCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFYD 121

Query: 123 EKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQTR-QDAEKSDTSPVAGKKASHDGP 181
           +K  RF      G++++R S LR  P   + ++  Q+     +  D  P  G+K   +  
Sbjct: 122 QKVNRFAYRT--GSEIIRMS-LRHKPAVSKRETVGQSLLHQTQMGDIWP--GRKIIQERQ 176

Query: 182 KRKGFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLNDQ 241
           K    L              PK  +G+S +L+ + +   S  +    D  ST   D  D+
Sbjct: 177 KEPSVLFE-----------VPKLKSGKS-ALEAESESLDSFTA----DSDSTSRRDSLDK 220

Query: 242 EPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKSH 301
                       +G+ P  +   AP ++        + G +N + +   E   ++ T+  
Sbjct: 221 ------------SGLFPEWKKMSAPKSQVEKET---QPGGQNVVFVDEGEMIFKKNTRKI 265

Query: 302 RRNTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVSIRSKSVPGALDKDSLEETE 361
            R                S+ ++S +DL          ++  RSKSVPG       EE E
Sbjct: 266 LR---------------PSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGLNVDMEEEEEE 310

Query: 362 ESIDALVSSQLSTNTHRLASGLSTSSQAGSDRKWTYLNVPDADSDTTSLNSMMSVYSETG 421
           E ID LV        HR     S S Q+GS                +++ SMMS+YSE G
Sbjct: 311 EDIDHLVK------LHRQKLARS-SMQSGSSM--------------STIGSMMSIYSEAG 349

Query: 422 DYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNN 481
           D+GN+ V+G I   + Y  +T  L + VK C  LA  DE K+R++ YVK+YLLPDKSR  
Sbjct: 350 DFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQG 409

Query: 482 KRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWN 540
           KRKT I+  T NP ++ETL+Y I  + L  RTLQ SVWH+ RFGRN+FLGE EI  DSW 
Sbjct: 410 KRKTSIKRDTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWK 469

Query: 541 FENPTDEWFVLQPKVEFAPDIGL-QYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGK 599
            +   D    L  K+      GL  +KGEL V L+YIP              +KT   G 
Sbjct: 470 LDKKLDHCLPLHGKISAESPTGLPSHKGELVVSLKYIP-------------ASKTPVGGD 516

Query: 600 KKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNP 659
           +K+S    GG L+V+IKEAKNLTA K+GGTSDSFVKGYLLP  +KA+K KT V+KK++NP
Sbjct: 517 RKKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNP 576

Query: 660 QWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQ 719
            +NHTF+++G+  +D++++CLELT+WD+E  +SN FLGGVRL  G+G+S+G+ VDWMDS 
Sbjct: 577 HYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDST 636

Query: 720 GEEQRLWQKMANNPGTPFEGVLMLRSSMGKCRL 752
           GEE  LWQKM   PG+  EG L LRSSM K +L
Sbjct: 637 GEEVSLWQKMRQYPGSWAEGTLQLRSSMAKQKL 669


>gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens]
          Length = 935

 Score =  270 bits (689), Expect = 5e-72
 Identities = 197/630 (31%), Positives = 307/630 (48%), Gaps = 74/630 (11%)

Query: 130 QVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAE-----KSDTSPVAGKKASHDGPKRK 184
           + +VL +D ++   +  +   EE QS  +  Q  +     +S +SP   K  +H      
Sbjct: 356 EFSVLESDRLKNG-MEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSG 414

Query: 185 GFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLNDQEPG 244
            F ++   S    E++T +                +S+++ P  +     SS+L   E  
Sbjct: 415 SFPINGLHS--HSEVLTARP---------------QSMENSPTINEPKDKSSELTRLESV 457

Query: 245 -PRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKSHRR 303
            PR+P    S+ V P     P  S+R       R+ G E        E  S  L    R 
Sbjct: 458 LPRSPADELSHCVEPEPSQVPGGSSR------DRQQGSE--------EEPSPVLKTLERS 503

Query: 304 NTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVSIRSKSVPGALDKDSLEETEES 363
                PS ++   S  S       +  E     +ED  ++ ++        D L+   +S
Sbjct: 504 AARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAEDVSTVPTQPDNPFSHPDKLKRMSKS 563

Query: 364 IDALVSSQLSTNTHRLASGLSTSSQAGSDRKWTYLNVPDADSDTTSLNSM----MSVYSE 419
           + A +  +        AS  S           +  N+  + S  TSL+S+    MSVYS 
Sbjct: 564 VPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNL-SSSSGMTSLSSVSGSVMSVYS- 621

Query: 420 TGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSR 479
            GD+GN++V G I   I Y      L++FV  C++LA  D KKQR+D YVK+YLLPDK +
Sbjct: 622 -GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGK 680

Query: 480 NNKRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDS 538
             K+KT +   T NP +NE L+Y I    L+T+ L LS+WH D F RNSFLGEVE+  ++
Sbjct: 681 MGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLET 740

Query: 539 WNFENPTDE---WFVLQPKVEFAP-DIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKT 594
           W+++N  ++   W+ L+ K   AP  +  + +GE+ + L+Y+         PE + G K 
Sbjct: 741 WDWDNKQNKQLRWYPLKRKT--APVALEAENRGEMKLALQYV---------PEPVPGKK- 788

Query: 595 FKKGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIK 654
                     + + G + +++KE  +L  ++ G   +SFVK  +LPD S+ ++ KT  + 
Sbjct: 789 ----------LPTTGEVHIWVKECLDLPLLR-GSHLNSFVKCTILPDTSRKSRQKTRAVG 837

Query: 655 KSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVD 714
           K+ NP +NHT ++ G  P+D+   C+ELT+WD     +N FLGG+R+  G+G S+G  VD
Sbjct: 838 KTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTEVD 896

Query: 715 WMDSQGEEQRLWQKMANNPGTPFEGVLMLR 744
           WMDS  EE  LW+KM N+P T  E  L LR
Sbjct: 897 WMDSTSEEVALWEKMVNSPNTWIEATLPLR 926



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 23/56 (41%), Positives = 36/56 (64%), Gaps = 3/56 (5%)

Query: 8  INLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNEL---LEAKRRSGKTQQEA 60
          I+LSFL + E+E I+ VL+RD  LK+ E++R+R L  ++    + K  SG+   EA
Sbjct: 2  IDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEA 57



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 56/263 (21%), Positives = 112/263 (42%), Gaps = 32/263 (12%)

Query: 111 QLRIITGEWFFEEKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAEKSDTSP 170
           QL+ ++G+WF+E KAKR +   + G D++R S+ ++ P     QS+++    A++S  + 
Sbjct: 45  QLKNMSGQWFYEAKAKRHRD-KIHGADIIRASMRKKRPQIAAEQSKDR-ENGAKESWVNN 102

Query: 171 VAGKKASHDGPKRKGFLLSKFRSAT----RGEIITPKTDTGRSYSLDLDGQHFRSLK-SP 225
           V   K +   P+  G +      A        ++ P +       +D+  ++ R    SP
Sbjct: 103 V--NKDAFLPPELAGVVEEPEEDAAPASPSSSVVNPASSV-----IDMSQENTRKPNVSP 155

Query: 226 PGSDRGSTGSSDLNDQEPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSM 285
               +    SS L +     +T      NG             RT     S+E     S 
Sbjct: 156 EKQRKNPFNSSKLPEGHSSQQTKNEQSKNG-------------RTGLFQTSKEDELSESK 202

Query: 286 DLAAIEGTS-QELTKSHRR---NTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTV 341
           + + +  TS Q+L KS +     ++G+   A    +       ++L+  ++ +   + T 
Sbjct: 203 EKSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARKMIYKSTDLNKDDNQSFPRQRTD 262

Query: 342 SIRSKSVP-GALDKDSLEETEES 363
           S++++  P G L ++S   + +S
Sbjct: 263 SLKARGAPRGILKRNSSSSSTDS 285


>gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens]
          Length = 934

 Score =  270 bits (689), Expect = 5e-72
 Identities = 197/630 (31%), Positives = 307/630 (48%), Gaps = 74/630 (11%)

Query: 130 QVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAE-----KSDTSPVAGKKASHDGPKRK 184
           + +VL +D ++   +  +   EE QS  +  Q  +     +S +SP   K  +H      
Sbjct: 355 EFSVLESDRLKNG-MEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSG 413

Query: 185 GFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLNDQEPG 244
            F ++   S    E++T +                +S+++ P  +     SS+L   E  
Sbjct: 414 SFPINGLHS--HSEVLTARP---------------QSMENSPTINEPKDKSSELTRLESV 456

Query: 245 -PRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKSHRR 303
            PR+P    S+ V P     P  S+R       R+ G E        E  S  L    R 
Sbjct: 457 LPRSPADELSHCVEPEPSQVPGGSSR------DRQQGSE--------EEPSPVLKTLERS 502

Query: 304 NTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVSIRSKSVPGALDKDSLEETEES 363
                PS ++   S  S       +  E     +ED  ++ ++        D L+   +S
Sbjct: 503 AARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAEDVSTVPTQPDNPFSHPDKLKRMSKS 562

Query: 364 IDALVSSQLSTNTHRLASGLSTSSQAGSDRKWTYLNVPDADSDTTSLNSM----MSVYSE 419
           + A +  +        AS  S           +  N+  + S  TSL+S+    MSVYS 
Sbjct: 563 VPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNL-SSSSGMTSLSSVSGSVMSVYS- 620

Query: 420 TGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSR 479
            GD+GN++V G I   I Y      L++FV  C++LA  D KKQR+D YVK+YLLPDK +
Sbjct: 621 -GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGK 679

Query: 480 NNKRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDS 538
             K+KT +   T NP +NE L+Y I    L+T+ L LS+WH D F RNSFLGEVE+  ++
Sbjct: 680 MGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLET 739

Query: 539 WNFENPTDE---WFVLQPKVEFAP-DIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKT 594
           W+++N  ++   W+ L+ K   AP  +  + +GE+ + L+Y+         PE + G K 
Sbjct: 740 WDWDNKQNKQLRWYPLKRKT--APVALEAENRGEMKLALQYV---------PEPVPGKK- 787

Query: 595 FKKGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIK 654
                     + + G + +++KE  +L  ++ G   +SFVK  +LPD S+ ++ KT  + 
Sbjct: 788 ----------LPTTGEVHIWVKECLDLPLLR-GSHLNSFVKCTILPDTSRKSRQKTRAVG 836

Query: 655 KSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVD 714
           K+ NP +NHT ++ G  P+D+   C+ELT+WD     +N FLGG+R+  G+G S+G  VD
Sbjct: 837 KTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTEVD 895

Query: 715 WMDSQGEEQRLWQKMANNPGTPFEGVLMLR 744
           WMDS  EE  LW+KM N+P T  E  L LR
Sbjct: 896 WMDSTSEEVALWEKMVNSPNTWIEATLPLR 925



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 55/262 (20%), Positives = 111/262 (42%), Gaps = 31/262 (11%)

Query: 111 QLRIITGEWFFEEKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAEKSDTSP 170
           QL+ ++G+WF+E KAKR +   + G D++R S+ ++ P     QS+++    A++S  + 
Sbjct: 45  QLKNMSGQWFYEAKAKRHRD-KIHGADIIRASMRKKRPQIAAEQSKDR-ENGAKESWVNN 102

Query: 171 VAGKKASHDGPKRKGFLLSKFRSAT----RGEIITPKTDTGRSYSLDLDGQHFRSLKSPP 226
           V   K +   P+  G +      A        ++ P +       +D+  ++ R     P
Sbjct: 103 V--NKDAFLPPELAGVVEEPEEDAAPASPSSSVVNPASSV-----IDMSQENTRKPNVSP 155

Query: 227 GSDRGSTGSSDLNDQEPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMD 286
              +    SS L +     +T      NG             RT     S+E     S +
Sbjct: 156 EKRKNPFNSSKLPEGHSSQQTKNEQSKNG-------------RTGLFQTSKEDELSESKE 202

Query: 287 LAAIEGTS-QELTKSHRR---NTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVS 342
            + +  TS Q+L KS +     ++G+   A    +       ++L+  ++ +   + T S
Sbjct: 203 KSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARKMIYKSTDLNKDDNQSFPRQRTDS 262

Query: 343 IRSKSVP-GALDKDSLEETEES 363
           ++++  P G L ++S   + +S
Sbjct: 263 LKARGAPRGILKRNSSSSSTDS 284



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 23/56 (41%), Positives = 36/56 (64%), Gaps = 3/56 (5%)

Query: 8  INLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNEL---LEAKRRSGKTQQEA 60
          I+LSFL + E+E I+ VL+RD  LK+ E++R+R L  ++    + K  SG+   EA
Sbjct: 2  IDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEA 57


>gi|46255064 synaptotagmin-like 2 isoform d [Homo sapiens]
          Length = 1256

 Score =  258 bits (659), Expect = 1e-68
 Identities = 157/411 (38%), Positives = 234/411 (56%), Gaps = 44/411 (10%)

Query: 339  DTVSIRSKSVPGALDKDSLEETEESIDALVSSQLSTNTHRLASGLSTSSQAGSDRKWTYL 398
            D +   SKSVP  L  +S ++ E    +  S QLS +    +S  + SS +G        
Sbjct: 876  DKLKRMSKSVPAFLQDES-DDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMT------ 928

Query: 399  NVPDADSDTTSLNSMMSVYSETGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIG 458
                  S ++   S+MSVYS  GD+GN++V G I   I Y      L++FV  C++LA  
Sbjct: 929  ------SLSSVSGSVMSVYS--GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAA 980

Query: 459  DEKKQRTDAYVKSYLLPDKSRNNKRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSV 517
            D KKQR+D YVK+YLLPDK +  K+KT +   T NP +NE L+Y I    L+T+ L LS+
Sbjct: 981  DVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSI 1040

Query: 518  WHYDRFGRNSFLGEVEIPFDSWNFENPTDE---WFVLQPKVEFAP-DIGLQYKGELTVVL 573
            WH D F RNSFLGEVE+  ++W+++N  ++   W+ L+ K   AP  +  + +GE+ + L
Sbjct: 1041 WHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKT--APVALEAENRGEMKLAL 1098

Query: 574  RYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSF 633
            +Y+         PE + G K           + + G + +++KE  +L  ++ G   +SF
Sbjct: 1099 QYV---------PEPVPGKK-----------LPTTGEVHIWVKECLDLPLLR-GSHLNSF 1137

Query: 634  VKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSN 693
            VK  +LPD S+ ++ KT  + K+ NP +NHT ++ G  P+D+   C+ELT+WD     +N
Sbjct: 1138 VKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TN 1196

Query: 694  IFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFEGVLMLR 744
             FLGG+R+  G+G S+G  VDWMDS  EE  LW+KM N+P T  E  L LR
Sbjct: 1197 QFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLR 1247


>gi|46255062 synaptotagmin-like 2 isoform c [Homo sapiens]
          Length = 1272

 Score =  258 bits (659), Expect = 1e-68
 Identities = 157/411 (38%), Positives = 234/411 (56%), Gaps = 44/411 (10%)

Query: 339  DTVSIRSKSVPGALDKDSLEETEESIDALVSSQLSTNTHRLASGLSTSSQAGSDRKWTYL 398
            D +   SKSVP  L  +S ++ E    +  S QLS +    +S  + SS +G        
Sbjct: 892  DKLKRMSKSVPAFLQDES-DDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMT------ 944

Query: 399  NVPDADSDTTSLNSMMSVYSETGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIG 458
                  S ++   S+MSVYS  GD+GN++V G I   I Y      L++FV  C++LA  
Sbjct: 945  ------SLSSVSGSVMSVYS--GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAA 996

Query: 459  DEKKQRTDAYVKSYLLPDKSRNNKRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSV 517
            D KKQR+D YVK+YLLPDK +  K+KT +   T NP +NE L+Y I    L+T+ L LS+
Sbjct: 997  DVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSI 1056

Query: 518  WHYDRFGRNSFLGEVEIPFDSWNFENPTDE---WFVLQPKVEFAP-DIGLQYKGELTVVL 573
            WH D F RNSFLGEVE+  ++W+++N  ++   W+ L+ K   AP  +  + +GE+ + L
Sbjct: 1057 WHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKT--APVALEAENRGEMKLAL 1114

Query: 574  RYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSF 633
            +Y+         PE + G K           + + G + +++KE  +L  ++ G   +SF
Sbjct: 1115 QYV---------PEPVPGKK-----------LPTTGEVHIWVKECLDLPLLR-GSHLNSF 1153

Query: 634  VKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSN 693
            VK  +LPD S+ ++ KT  + K+ NP +NHT ++ G  P+D+   C+ELT+WD     +N
Sbjct: 1154 VKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TN 1212

Query: 694  IFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFEGVLMLR 744
             FLGG+R+  G+G S+G  VDWMDS  EE  LW+KM N+P T  E  L LR
Sbjct: 1213 QFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLR 1263


>gi|15011900 synaptotagmin-like 2 isoform b [Homo sapiens]
          Length = 376

 Score =  257 bits (657), Expect = 2e-68
 Identities = 156/405 (38%), Positives = 232/405 (57%), Gaps = 44/405 (10%)

Query: 345 SKSVPGALDKDSLEETEESIDALVSSQLSTNTHRLASGLSTSSQAGSDRKWTYLNVPDAD 404
           SKSVP  L  +S ++ E    +  S QLS +    +S  + SS +G              
Sbjct: 2   SKSVPAFLQDES-DDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMT------------ 48

Query: 405 SDTTSLNSMMSVYSETGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQR 464
           S ++   S+MSVYS  GD+GN++V G I   I Y      L++FV  C++LA  D KKQR
Sbjct: 49  SLSSVSGSVMSVYS--GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQR 106

Query: 465 TDAYVKSYLLPDKSRNNKRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRF 523
           +D YVK+YLLPDK +  K+KT +   T NP +NE L+Y I    L+T+ L LS+WH D F
Sbjct: 107 SDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTF 166

Query: 524 GRNSFLGEVEIPFDSWNFENPTDE---WFVLQPKVEFAP-DIGLQYKGELTVVLRYIPPE 579
            RNSFLGEVE+  ++W+++N  ++   W+ L+ K   AP  +  + +GE+ + L+Y+   
Sbjct: 167 KRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKT--APVALEAENRGEMKLALQYV--- 221

Query: 580 ENLMLPPEQLQGNKTFKKGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLL 639
                 PE + G K           + + G + +++KE  +L  ++ G   +SFVK  +L
Sbjct: 222 ------PEPVPGKK-----------LPTTGEVHIWVKECLDLPLLR-GSHLNSFVKCTIL 263

Query: 640 PDDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGV 699
           PD S+ ++ KT  + K+ NP +NHT ++ G  P+D+   C+ELT+WD     +N FLGG+
Sbjct: 264 PDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGL 322

Query: 700 RLNSGSGVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFEGVLMLR 744
           R+  G+G S+G  VDWMDS  EE  LW+KM N+P T  E  L LR
Sbjct: 323 RIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLR 367


>gi|46255066 synaptotagmin-like 2 isoform e [Homo sapiens]
          Length = 376

 Score =  257 bits (657), Expect = 2e-68
 Identities = 156/405 (38%), Positives = 232/405 (57%), Gaps = 44/405 (10%)

Query: 345 SKSVPGALDKDSLEETEESIDALVSSQLSTNTHRLASGLSTSSQAGSDRKWTYLNVPDAD 404
           SKSVP  L  +S ++ E    +  S QLS +    +S  + SS +G              
Sbjct: 2   SKSVPAFLQDES-DDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMT------------ 48

Query: 405 SDTTSLNSMMSVYSETGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQR 464
           S ++   S+MSVYS  GD+GN++V G I   I Y      L++FV  C++LA  D KKQR
Sbjct: 49  SLSSVSGSVMSVYS--GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQR 106

Query: 465 TDAYVKSYLLPDKSRNNKRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRF 523
           +D YVK+YLLPDK +  K+KT +   T NP +NE L+Y I    L+T+ L LS+WH D F
Sbjct: 107 SDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTF 166

Query: 524 GRNSFLGEVEIPFDSWNFENPTDE---WFVLQPKVEFAP-DIGLQYKGELTVVLRYIPPE 579
            RNSFLGEVE+  ++W+++N  ++   W+ L+ K   AP  +  + +GE+ + L+Y+   
Sbjct: 167 KRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKT--APVALEAENRGEMKLALQYV--- 221

Query: 580 ENLMLPPEQLQGNKTFKKGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLL 639
                 PE + G K           + + G + +++KE  +L  ++ G   +SFVK  +L
Sbjct: 222 ------PEPVPGKK-----------LPTTGEVHIWVKECLDLPLLR-GSHLNSFVKCTIL 263

Query: 640 PDDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGV 699
           PD S+ ++ KT  + K+ NP +NHT ++ G  P+D+   C+ELT+WD     +N FLGG+
Sbjct: 264 PDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGL 322

Query: 700 RLNSGSGVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFEGVLMLR 744
           R+  G+G S+G  VDWMDS  EE  LW+KM N+P T  E  L LR
Sbjct: 323 RIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLR 367


>gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens]
          Length = 910

 Score =  256 bits (654), Expect = 5e-68
 Identities = 197/626 (31%), Positives = 301/626 (48%), Gaps = 90/626 (14%)

Query: 130 QVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAE-----KSDTSPVAGKKASHDGPKRK 184
           + +VL +D ++   +  +   EE QS  +  Q  +     +S +SP   K  +H      
Sbjct: 355 EFSVLESDRLKNG-MEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSG 413

Query: 185 GFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLNDQEPG 244
            F ++   S    E++T +                +S+++ P  +     SS+L   E  
Sbjct: 414 SFPINGLHS--HSEVLTARP---------------QSMENSPTINEPKDKSSELTRLESV 456

Query: 245 -PRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKSHRR 303
            PR+P    S+ V P     P  S+R       R+ G E        E  S  L    R 
Sbjct: 457 LPRSPADELSHCVEPEPSQVPGGSSR------DRQQGSE--------EEPSPVLKTLERS 502

Query: 304 NTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVSIRSKSVPGALDKDSLEETEES 363
                PS ++   S  S       +  E     +ED      K V           T E 
Sbjct: 503 AARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAEDDEKPDQKPV-----------TNEC 551

Query: 364 IDALVSSQLSTNTHRLASGLSTSSQAGSDRKWTYLNVPDADSDTTSLNSMMSVYSETGDY 423
           +      ++ST   +  +  S   +     K    +VP    D  S  S+MSVYS  GD+
Sbjct: 552 VP-----RISTVPTQPDNPFSHPDKLKRMSK----SVPAFLQDEVS-GSVMSVYS--GDF 599

Query: 424 GNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKR 483
           GN++V G I   I Y      L++FV  C++LA  D KKQR+D YVK+YLLPDK +  K+
Sbjct: 600 GNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKK 659

Query: 484 KTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFE 542
           KT +   T NP +NE L+Y I    L+T+ L LS+WH D F RNSFLGEVE+  ++W+++
Sbjct: 660 KTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWD 719

Query: 543 NPTDE---WFVLQPKVEFAP-DIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKG 598
           N  ++   W+ L+ K   AP  +  + +GE+ + L+Y+         PE + G K     
Sbjct: 720 NKQNKQLRWYPLKRKT--APVALEAENRGEMKLALQYV---------PEPVPGKK----- 763

Query: 599 KKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVN 658
                 + + G + +++KE  +L  ++ G   +SFVK  +LPD S+ ++ KT  + K+ N
Sbjct: 764 ------LPTTGEVHIWVKECLDLPLLR-GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTN 816

Query: 659 PQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDS 718
           P +NHT ++ G  P+D+   C+ELT+WD     +N FLGG+R+  G+G S+G  VDWMDS
Sbjct: 817 PIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDS 875

Query: 719 QGEEQRLWQKMANNPGTPFEGVLMLR 744
             EE  LW+KM N+P T  E  L LR
Sbjct: 876 TSEEVALWEKMVNSPNTWIEATLPLR 901



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 55/262 (20%), Positives = 111/262 (42%), Gaps = 31/262 (11%)

Query: 111 QLRIITGEWFFEEKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAEKSDTSP 170
           QL+ ++G+WF+E KAKR +   + G D++R S+ ++ P     QS+++    A++S  + 
Sbjct: 45  QLKNMSGQWFYEAKAKRHRD-KIHGADIIRASMRKKRPQIAAEQSKDR-ENGAKESWVNN 102

Query: 171 VAGKKASHDGPKRKGFLLSKFRSAT----RGEIITPKTDTGRSYSLDLDGQHFRSLKSPP 226
           V   K +   P+  G +      A        ++ P +       +D+  ++ R     P
Sbjct: 103 V--NKDAFLPPELAGVVEEPEEDAAPASPSSSVVNPASSV-----IDMSQENTRKPNVSP 155

Query: 227 GSDRGSTGSSDLNDQEPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMD 286
              +    SS L +     +T      NG             RT     S+E     S +
Sbjct: 156 EKRKNPFNSSKLPEGHSSQQTKNEQSKNG-------------RTGLFQTSKEDELSESKE 202

Query: 287 LAAIEGTS-QELTKSHRR---NTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVS 342
            + +  TS Q+L KS +     ++G+   A    +       ++L+  ++ +   + T S
Sbjct: 203 KSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARKMIYKSTDLNKDDNQSFPRQRTDS 262

Query: 343 IRSKSVP-GALDKDSLEETEES 363
           ++++  P G L ++S   + +S
Sbjct: 263 LKARGAPRGILKRNSSSSSTDS 284



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 23/56 (41%), Positives = 36/56 (64%), Gaps = 3/56 (5%)

Query: 8  INLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNEL---LEAKRRSGKTQQEA 60
          I+LSFL + E+E I+ VL+RD  LK+ E++R+R L  ++    + K  SG+   EA
Sbjct: 2  IDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEA 57


>gi|46255068 synaptotagmin-like 2 isoform f [Homo sapiens]
          Length = 365

 Score =  252 bits (643), Expect = 1e-66
 Identities = 143/351 (40%), Positives = 211/351 (60%), Gaps = 35/351 (9%)

Query: 403 ADSDTTSLNSM----MSVYSETGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIG 458
           + S  TSL+S+    MSVYS  GD+GN++V G I   I Y      L++FV  C++LA  
Sbjct: 32  SSSGMTSLSSVSGSVMSVYS--GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAA 89

Query: 459 DEKKQRTDAYVKSYLLPDKSRNNKRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSV 517
           D KKQR+D YVK+YLLPDK +  K+KT +   T NP +NE L+Y I    L+T+ L LS+
Sbjct: 90  DVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSI 149

Query: 518 WHYDRFGRNSFLGEVEIPFDSWNFENPTDE---WFVLQPKVEFAP-DIGLQYKGELTVVL 573
           WH D F RNSFLGEVE+  ++W+++N  ++   W+ L+ K   AP  +  + +GE+ + L
Sbjct: 150 WHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKT--APVALEAENRGEMKLAL 207

Query: 574 RYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSF 633
           +Y+         PE + G K           + + G + +++KE  +L  ++ G   +SF
Sbjct: 208 QYV---------PEPVPGKK-----------LPTTGEVHIWVKECLDLPLLR-GSHLNSF 246

Query: 634 VKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSN 693
           VK  +LPD S+ ++ KT  + K+ NP +NHT ++ G  P+D+   C+ELT+WD     +N
Sbjct: 247 VKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TN 305

Query: 694 IFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFEGVLMLR 744
            FLGG+R+  G+G S+G  VDWMDS  EE  LW+KM N+P T  E  L LR
Sbjct: 306 QFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLR 356


>gi|244790016 synaptotagmin-like 2 isoform h [Homo sapiens]
          Length = 336

 Score =  251 bits (642), Expect = 1e-66
 Identities = 143/351 (40%), Positives = 210/351 (59%), Gaps = 32/351 (9%)

Query: 399 NVPDADSDTTSLNSMMSVYSETGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIG 458
           +VP    D  S  S+MSVYS  GD+GN++V G I   I Y      L++FV  C++LA  
Sbjct: 4   SVPAFLQDEVS-GSVMSVYS--GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAA 60

Query: 459 DEKKQRTDAYVKSYLLPDKSRNNKRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSV 517
           D KKQR+D YVK+YLLPDK +  K+KT +   T NP +NE L+Y I    L+T+ L LS+
Sbjct: 61  DVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSI 120

Query: 518 WHYDRFGRNSFLGEVEIPFDSWNFENPTDE---WFVLQPKVEFAP-DIGLQYKGELTVVL 573
           WH D F RNSFLGEVE+  ++W+++N  ++   W+ L+ K   AP  +  + +GE+ + L
Sbjct: 121 WHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKT--APVALEAENRGEMKLAL 178

Query: 574 RYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSF 633
           +Y+         PE + G K           + + G + +++KE  +L  ++ G   +SF
Sbjct: 179 QYV---------PEPVPGKK-----------LPTTGEVHIWVKECLDLPLLR-GSHLNSF 217

Query: 634 VKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSN 693
           VK  +LPD S+ ++ KT  + K+ NP +NHT ++ G  P+D+   C+ELT+WD     +N
Sbjct: 218 VKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TN 276

Query: 694 IFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFEGVLMLR 744
            FLGG+R+  G+G S+G  VDWMDS  EE  LW+KM N+P T  E  L LR
Sbjct: 277 QFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLR 327


>gi|14249614 synaptotagmin-like 1 [Homo sapiens]
          Length = 550

 Score =  232 bits (591), Expect = 1e-60
 Identities = 137/351 (39%), Positives = 209/351 (59%), Gaps = 36/351 (10%)

Query: 403 ADSDTTSLNSMM---SVYSETGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGD 459
           + S  +SLNS     S  S +GD   V+V G +   + Y      L + V  C+ LA   
Sbjct: 226 SSSSVSSLNSSTLSGSQMSLSGDAEAVQVRGSVHFALHYEPGAAELRVHVIQCQGLAAA- 284

Query: 460 EKKQRTDAYVKSYLLPDKSRNNKRKTKIRT-GTNPEFNETLKYTISHTQLETRTLQLSVW 518
            +++R+D YVKSYLLPDK   +KRKT ++    NP FNETL+Y++   +L+ R L LSVW
Sbjct: 285 -RRRRSDPYVKSYLLPDKQ--SKRKTAVKKRNLNPVFNETLRYSVPQAELQGRVLSLSVW 341

Query: 519 HYDRFGRNSFLGEVEIPFDSWNF-ENPTDEWFVLQPKVEFAPDIGLQYKGELTVVLRYIP 577
           H +  GRN FLGEVE+P D+W++   PT  W  LQP+V  +PD  L  +G L + L+Y+P
Sbjct: 342 HRESLGRNIFLGEVEVPLDTWDWGSEPT--WLPLQPRVPPSPD-DLPSRGLLALSLKYVP 398

Query: 578 P-EENLMLPPEQLQGNKTFKKGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKG 636
              E   LPP                      G L  ++KEA++L  +++ G+ D++V+ 
Sbjct: 399 AGSEGAGLPP---------------------SGELHFWVKEARDLLPLRA-GSLDTYVQC 436

Query: 637 YLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFL 696
           ++LPDDS+A++ +T V+++S++P +NHT ++ G  P D++  C EL++WD  A  +N  L
Sbjct: 437 FVLPDDSQASRQRTRVVRRSLSPVFNHTMVYDGFGPADLRQACAELSLWDHGAL-ANRQL 495

Query: 697 GGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFEGVLMLRSSM 747
           GG RL+ G+G S+G  V WMDS  EE++LWQ +   P    +G+L LR+++
Sbjct: 496 GGTRLSLGTGSSYGLQVPWMDSTPEEKQLWQALLEQPCEWVDGLLPLRTNL 546



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 40/182 (21%), Positives = 81/182 (44%), Gaps = 21/182 (11%)

Query: 86  LRVCRECRVAGPNGSWKCTVCDKIAQLRIITGEWFFEEKAKRFKQVNVLGTDVVRQSILR 145
           LR   E RV+      + +V D   QL+I+TG+WF E +++R    +  G+D+VR S+ R
Sbjct: 55  LRQLEEGRVS----KLRASVADP-GQLKILTGDWFQEARSQRHHNAH-FGSDLVRASMRR 108

Query: 146 -RSPGAEEVQSQEQTRQDAEKSDTSPVAGKKASHDGPKRKGFLLSKFRSATRGEIITPKT 204
            +S   ++    ++  + A K        +    + P+ +   L +  ++   E    + 
Sbjct: 109 KKSTRGDQAPGHDREAEAAVKEKEEGPEPRLTIDEAPQER---LRETEASDPEEASQAQE 165

Query: 205 DTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLNDQEPGPRTPKSSRSNGVTPGTQSSP 264
           D G+        Q   + ++ P  +  S G     +QEP P+  ++  ++ +    + +P
Sbjct: 166 DPGQG------DQQVCAEEADPELEPASGG-----EQEPRPQQAQTKAASQILENGEEAP 214

Query: 265 AP 266
            P
Sbjct: 215 GP 216



 Score = 38.9 bits (89), Expect = 0.018
 Identities = 17/36 (47%), Positives = 28/36 (77%)

Query: 8  INLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLK 43
          ++LSFL + E+E I GVL+RD  L+++E+ R+ KL+
Sbjct: 32 LDLSFLTEEEQEAIAGVLQRDARLRQLEEGRVSKLR 67


>gi|110227631 synaptotagmin-like 3 [Homo sapiens]
          Length = 542

 Score =  220 bits (560), Expect = 4e-57
 Identities = 136/340 (40%), Positives = 192/340 (56%), Gaps = 22/340 (6%)

Query: 409 SLNSMMSVYSETGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAY 468
           SL S+ S  +E G++ N  V+GEI   I YC+KT  L I +K C+NLA G+EKK++ + Y
Sbjct: 219 SLISIDSTCTEMGNFDNANVTGEIEFAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPY 278

Query: 469 VKSYLLPDKSRNNKRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNS 527
           VK+YLLPD+S   KRKT ++  T +P F ETLKY ++  QL TR LQ+SVWH     R  
Sbjct: 279 VKTYLLPDRSSQGKRKTGVQRNTVDPTFQETLKYQVAPAQLVTRQLQVSVWHLGTLARRV 338

Query: 528 FLGEVEIPFDSWNFENPTDE---WFVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLML 584
           FLGEV IP  +W+FE+ T +   W  L+ K E   D   Q  GELTV  + + P      
Sbjct: 339 FLGEVIIPLATWDFEDSTTQSFRWHPLRAKAEKYEDSVPQSNGELTVRAKLVLPSR---- 394

Query: 585 PPEQLQGNKTFKKGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSK 644
            P +LQ     +  +  + P + G +  V +  AKNL  V+  GT +SFVKG L   D +
Sbjct: 395 -PRKLQ-----EAQEGTDQPSLHGQLCLV-VLGAKNL-PVRPDGTLNSFVKGCLTLPDQQ 446

Query: 645 ATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSN-IFLGGVRLNS 703
             + K+ V++K   PQW H+F+FSG+ P  ++   LELT+WD+  F  N   LGG RL S
Sbjct: 447 KLRLKSPVLRKQACPQWKHSFVFSGVTPAQLRQSSLELTVWDQALFGMNDRLLGGTRLGS 506

Query: 704 GSGVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFEGVLML 743
               + G      D+    +  WQK+ ++P    +  L+L
Sbjct: 507 KGDTAVGG-----DACSLSKLQWQKVLSSPNLWTDMTLVL 541



 Score =  102 bits (254), Expect = 1e-21
 Identities = 72/237 (30%), Positives = 110/237 (46%), Gaps = 27/237 (11%)

Query: 8   INLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTQ--QEASRVCV 65
           I+LS L + E+E IL VL RD+ ++  E++R RKLK  L   + +  K    +   + C 
Sbjct: 5   IDLSALKELEREAILQVLYRDQAVQNTEEERTRKLKTHLQHLRWKGAKNTDWEHKEKCCA 64

Query: 66  HCHRNLGLIFDRGDPCQACSLRVCRECRV-AGPNGSWKCTVCDKIAQLRIITGEWFFEEK 124
            C + LG +  RG  C+ CS RVC +CRV      +WKCTVC +   ++I TGEWF+EE+
Sbjct: 65  RCQQVLGFLLHRGAVCRGCSHRVCAQCRVFLRGTHAWKCTVCFEDRNVKIKTGEWFYEER 124

Query: 125 AKRF----KQVNVLG------------------TDVVRQSILRRSPGAEEVQSQ--EQTR 160
           AK+F    K   V G                     V +S   RSPG +       +   
Sbjct: 125 AKKFPTGGKHETVGGQLLQSYQKLSKISVVPPTPPPVSESQCSRSPGRKVSAPDILKPLN 184

Query: 161 QDAEKSDTSPVAGKKASHDGPKRKGFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQ 217
           Q+  K  T+P+  ++     P         FR  +   I +  T+ G   + ++ G+
Sbjct: 185 QEDPKCSTNPILKQQNLPSSPAPSTIFSGGFRHGSLISIDSTCTEMGNFDNANVTGE 241


>gi|92859638 synaptotagmin V [Homo sapiens]
          Length = 386

 Score =  129 bits (323), Expect = 1e-29
 Identities = 91/307 (29%), Positives = 136/307 (44%), Gaps = 49/307 (15%)

Query: 430 GEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRT 489
           G +   + Y +++G L + +     LA  D     +D YV+ YLLPDK R  + K   +T
Sbjct: 110 GRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGS-SDPYVRVYLLPDKRRRYETKVHRQT 168

Query: 490 GTNPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTDEWF 549
             NP F ET  + + + +L  R L ++V+ +DRF RN  +GEV +P  S +   P   W 
Sbjct: 169 -LNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWR 227

Query: 550 VLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISGG 609
            LQ     AP    +  G++   LRY+P                             + G
Sbjct: 228 ELQA----APREEQEKLGDICFSLRYVP-----------------------------TAG 254

Query: 610 ILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSG 669
            L V + EAKNL  +  GG SD +VK +LL    K  K KT + K ++NP +N  F F  
Sbjct: 255 KLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFE- 313

Query: 670 IHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQKM 729
           +    ++ V +ELT+ D +    N  +G V + + +G             G   R W  M
Sbjct: 314 VPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAG-------------GAGLRHWADM 360

Query: 730 ANNPGTP 736
             NP  P
Sbjct: 361 LANPRRP 367


>gi|211059429 synaptotagmin II [Homo sapiens]
          Length = 419

 Score =  124 bits (310), Expect = 4e-28
 Identities = 89/308 (28%), Positives = 146/308 (47%), Gaps = 51/308 (16%)

Query: 430 GEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRT 489
           G++   + Y ++   L + V     L   D     +D YVK +LLPDK +  K +TK+  
Sbjct: 141 GKLQFSLDYDFQANQLTVGVLQAAELPALD-MGGTSDPYVKVFLLPDKKK--KYETKVHR 197

Query: 490 GT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTDEW 548
            T NP FNET  + + + +L  +TL ++++ +DRF ++  +GEV++P ++ +   P +EW
Sbjct: 198 KTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEW 257

Query: 549 FVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISG 608
             LQ   +  P    +  G++   LRY+P                             + 
Sbjct: 258 RDLQGGEKEEP----EKLGDICTSLRYVP-----------------------------TA 284

Query: 609 GILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFS 668
           G L V I EAKNL  +  GG SD +VK +L+ +  +  K KT V KK++NP +N +F F 
Sbjct: 285 GKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFE 344

Query: 669 GIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQK 728
            I  + I+ V + +T+ D +    N  +G + + S             ++ G E R W  
Sbjct: 345 -IPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGS-------------NATGTELRHWSD 390

Query: 729 MANNPGTP 736
           M  NP  P
Sbjct: 391 MLANPRRP 398


>gi|31543670 synaptotagmin II [Homo sapiens]
          Length = 419

 Score =  124 bits (310), Expect = 4e-28
 Identities = 89/308 (28%), Positives = 146/308 (47%), Gaps = 51/308 (16%)

Query: 430 GEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRT 489
           G++   + Y ++   L + V     L   D     +D YVK +LLPDK +  K +TK+  
Sbjct: 141 GKLQFSLDYDFQANQLTVGVLQAAELPALD-MGGTSDPYVKVFLLPDKKK--KYETKVHR 197

Query: 490 GT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTDEW 548
            T NP FNET  + + + +L  +TL ++++ +DRF ++  +GEV++P ++ +   P +EW
Sbjct: 198 KTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEW 257

Query: 549 FVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISG 608
             LQ   +  P    +  G++   LRY+P                             + 
Sbjct: 258 RDLQGGEKEEP----EKLGDICTSLRYVP-----------------------------TA 284

Query: 609 GILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFS 668
           G L V I EAKNL  +  GG SD +VK +L+ +  +  K KT V KK++NP +N +F F 
Sbjct: 285 GKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFE 344

Query: 669 GIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQK 728
            I  + I+ V + +T+ D +    N  +G + + S             ++ G E R W  
Sbjct: 345 -IPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGS-------------NATGTELRHWSD 390

Query: 729 MANNPGTP 736
           M  NP  P
Sbjct: 391 MLANPRRP 398


>gi|6005997 double C2-like domains, beta [Homo sapiens]
          Length = 412

 Score =  117 bits (294), Expect = 3e-26
 Identities = 81/241 (33%), Positives = 120/241 (49%), Gaps = 36/241 (14%)

Query: 466 DAYVKSYLLPDKSRNNKRKTK-IRTGTNPEFNETLKYT-ISHTQLETRTLQLSVWHYDRF 523
           D YVK +LLP  S+ NK +TK +R   NP +NETL Y  I+   +  +TL++SV   D+F
Sbjct: 163 DPYVKLHLLPGASKANKLRTKTLRNTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKF 222

Query: 524 GRNSFLGEVEIPFDSWNFENPTDEWFVLQPK---VEFAPDIGLQYKGELTVVLRYIPPEE 580
             N F+GE  +P       N T  + +   K   V+   D  L+ +G + + L+Y   ++
Sbjct: 223 RHNEFIGETRVPLKKLK-PNHTKTFNICLEKQLPVDKTEDKSLEERGRILISLKYSSQKQ 281

Query: 581 NLMLPPEQLQGNKTFKKGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLP 640
            L+                             V I    +L A+ + G SD +VK YL P
Sbjct: 282 GLL-----------------------------VGIVRCAHLAAMDANGYSDPYVKTYLRP 312

Query: 641 DDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVR 700
           D  K +KHKT V KK++NP++N  F +  I   D+    LE+T+WD +   SN F+GGV 
Sbjct: 313 DVDKKSKHKTAVKKKTLNPEFNEEFCYE-IKHGDLAKKSLEVTVWDYDIGKSNDFIGGVV 371

Query: 701 L 701
           L
Sbjct: 372 L 372



 Score = 76.6 bits (187), Expect = 8e-14
 Identities = 41/104 (39%), Positives = 59/104 (56%), Gaps = 2/104 (1%)

Query: 430 GEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRT 489
           G IL+ + Y  +  GL + +  C +LA  D     +D YVK+YL PD  + +K KT ++ 
Sbjct: 268 GRILISLKYSSQKQGLLVGIVRCAHLAAMDANGY-SDPYVKTYLRPDVDKKSKHKTAVKK 326

Query: 490 GT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEV 532
            T NPEFNE   Y I H  L  ++L+++VW YD    N F+G V
Sbjct: 327 KTLNPEFNEEFCYEIKHGDLAKKSLEVTVWDYDIGKSNDFIGGV 370



 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 32/91 (35%), Positives = 52/91 (57%)

Query: 611 LEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSGI 670
           L   I +AK L  +   G +D +VK +LLP  SKA K +T  ++ ++NP WN T  + GI
Sbjct: 143 LHCTITKAKGLKPMDHNGLADPYVKLHLLPGASKANKLRTKTLRNTLNPTWNETLTYYGI 202

Query: 671 HPQDIKNVCLELTIWDKEAFSSNIFLGGVRL 701
             +D+    L +++ D++ F  N F+G  R+
Sbjct: 203 TDEDMIRKTLRISVCDEDKFRHNEFIGETRV 233


>gi|209447073 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  116 bits (291), Expect = 7e-26
 Identities = 86/308 (27%), Positives = 144/308 (46%), Gaps = 51/308 (16%)

Query: 430 GEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRT 489
           G++   + Y ++   L + +     L   D     +D YVK +LLPDK +  K +TK+  
Sbjct: 144 GKLQYSLDYDFQNNQLLVGIIQAAELPALD-MGGTSDPYVKVFLLPDKKK--KFETKVHR 200

Query: 490 GT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTDEW 548
            T NP FNE   + + +++L  +TL ++V+ +DRF ++  +GE ++P ++ +F + T+EW
Sbjct: 201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEW 260

Query: 549 FVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISG 608
             LQ     A     +  G++   LRY+P                             + 
Sbjct: 261 RDLQS----AEKEEQEKLGDICFSLRYVP-----------------------------TA 287

Query: 609 GILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFS 668
           G L V I EAKNL  +  GG SD +VK +L+ +  +  K KT + K ++NP +N +F F 
Sbjct: 288 GKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFE 347

Query: 669 GIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQK 728
            +  + I+ V + +T+ D +    N  +G V +               +S G E R W  
Sbjct: 348 -VPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVG-------------YNSTGAELRHWSD 393

Query: 729 MANNPGTP 736
           M  NP  P
Sbjct: 394 MLANPRRP 401


>gi|5032139 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  116 bits (291), Expect = 7e-26
 Identities = 86/308 (27%), Positives = 144/308 (46%), Gaps = 51/308 (16%)

Query: 430 GEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRT 489
           G++   + Y ++   L + +     L   D     +D YVK +LLPDK +  K +TK+  
Sbjct: 144 GKLQYSLDYDFQNNQLLVGIIQAAELPALD-MGGTSDPYVKVFLLPDKKK--KFETKVHR 200

Query: 490 GT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTDEW 548
            T NP FNE   + + +++L  +TL ++V+ +DRF ++  +GE ++P ++ +F + T+EW
Sbjct: 201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEW 260

Query: 549 FVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISG 608
             LQ     A     +  G++   LRY+P                             + 
Sbjct: 261 RDLQS----AEKEEQEKLGDICFSLRYVP-----------------------------TA 287

Query: 609 GILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFS 668
           G L V I EAKNL  +  GG SD +VK +L+ +  +  K KT + K ++NP +N +F F 
Sbjct: 288 GKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFE 347

Query: 669 GIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQK 728
            +  + I+ V + +T+ D +    N  +G V +               +S G E R W  
Sbjct: 348 -VPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVG-------------YNSTGAELRHWSD 393

Query: 729 MANNPGTP 736
           M  NP  P
Sbjct: 394 MLANPRRP 401


>gi|209447070 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  116 bits (291), Expect = 7e-26
 Identities = 86/308 (27%), Positives = 144/308 (46%), Gaps = 51/308 (16%)

Query: 430 GEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRT 489
           G++   + Y ++   L + +     L   D     +D YVK +LLPDK +  K +TK+  
Sbjct: 144 GKLQYSLDYDFQNNQLLVGIIQAAELPALD-MGGTSDPYVKVFLLPDKKK--KFETKVHR 200

Query: 490 GT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTDEW 548
            T NP FNE   + + +++L  +TL ++V+ +DRF ++  +GE ++P ++ +F + T+EW
Sbjct: 201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEW 260

Query: 549 FVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISG 608
             LQ     A     +  G++   LRY+P                             + 
Sbjct: 261 RDLQS----AEKEEQEKLGDICFSLRYVP-----------------------------TA 287

Query: 609 GILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFS 668
           G L V I EAKNL  +  GG SD +VK +L+ +  +  K KT + K ++NP +N +F F 
Sbjct: 288 GKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFE 347

Query: 669 GIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQK 728
            +  + I+ V + +T+ D +    N  +G V +               +S G E R W  
Sbjct: 348 -VPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVG-------------YNSTGAELRHWSD 393

Query: 729 MANNPGTP 736
           M  NP  P
Sbjct: 394 MLANPRRP 401


>gi|38570146 synaptotagmin VII [Homo sapiens]
          Length = 403

 Score =  112 bits (280), Expect = 1e-24
 Identities = 85/289 (29%), Positives = 134/289 (46%), Gaps = 40/289 (13%)

Query: 430 GEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRT 489
           G I   + Y ++   L + +   + L   D     +D +VK YLLPDK    + K K R 
Sbjct: 137 GRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGT-SDPFVKIYLLPDKKHKLETKVK-RK 194

Query: 490 GTNPEFNETLKYT-ISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTDEW 548
             NP +NET  +    + ++  R L L V  YDRF RN  +GEV IP +  +       W
Sbjct: 195 NLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTFW 254

Query: 549 FVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISG 608
             L+P  +     G   +GEL + L Y P   +++                         
Sbjct: 255 KDLKPCSD-----GSGSRGELLLSLCYNPSANSII------------------------- 284

Query: 609 GILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFS 668
               V I +A+NL A+  GGTSD +VK +L+  D +  K KT+ +K+++NP +N +F F 
Sbjct: 285 ----VNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTMKRNLNPIFNESFAFD 340

Query: 669 GIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMD 717
            I  + ++   + +T+ DK+  S N  +G + L+  SG    K+  W D
Sbjct: 341 -IPTEKLRETTIIITVMDKDKLSRNDVIGKIYLSWKSGPGEVKH--WKD 386


>gi|47078261 double C2-like domains, alpha [Homo sapiens]
          Length = 400

 Score =  108 bits (271), Expect = 1e-23
 Identities = 87/278 (31%), Positives = 129/278 (46%), Gaps = 27/278 (9%)

Query: 466 DAYVKSYLLPDKSRNNKRKTKIRTGT-NPEFNETLKYT-ISHTQLETRTLQLSVWHYDRF 523
           D YVK +LLP   + NK KTK +  T NP +NE L Y+ I+   +  + L+++V   D+ 
Sbjct: 126 DPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKL 185

Query: 524 GRNSFLGEVEIPFDSWNFENPTDEWFVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLM 583
             N F+GE+ +P               L+ +V  A          ++  LR I      +
Sbjct: 186 SHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLASP------SSMSAALRGISCYLKEL 239

Query: 584 LPPEQLQGNKTFKKGKKKESPVISG---GILEVFIKEAKNLTAVKSGGTSDSFVKGYLLP 640
              EQ QG    ++G+   S   S    G+L V I    +L A+   G SD +VK YL P
Sbjct: 240 EQAEQGQGLLE-ERGRILLSLSYSSRRRGLL-VGILRCAHLAAMDVNGYSDPYVKTYLRP 297

Query: 641 DDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVR 700
           D  K +KHKT V KK++NP++N  F +  I    +    LE+T+WD +   SN F+GGV 
Sbjct: 298 DVDKKSKHKTCVKKKTLNPEFNEEFFYE-IELSTLATKTLEVTVWDYDIGKSNDFIGGVS 356

Query: 701 LNSGSGVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFE 738
           L  G             ++GE ++ W      P    E
Sbjct: 357 LGPG-------------ARGEARKHWSDCLQQPDAALE 381



 Score = 80.1 bits (196), Expect = 7e-15
 Identities = 45/112 (40%), Positives = 65/112 (58%), Gaps = 2/112 (1%)

Query: 424 GNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKR 483
           G ++  G ILL +SY  +  GL + +  C +LA  D     +D YVK+YL PD  + +K 
Sbjct: 247 GLLEERGRILLSLSYSSRRRGLLVGILRCAHLAAMDVNGY-SDPYVKTYLRPDVDKKSKH 305

Query: 484 KTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEI 534
           KT ++  T NPEFNE   Y I  + L T+TL+++VW YD    N F+G V +
Sbjct: 306 KTCVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSL 357



 Score = 63.5 bits (153), Expect = 7e-10
 Identities = 33/91 (36%), Positives = 49/91 (53%)

Query: 611 LEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSGI 670
           L   I  AK L  +   G +D +VK +LLP   KA K KT   + ++NP WN    +SGI
Sbjct: 106 LHCSILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGI 165

Query: 671 HPQDIKNVCLELTIWDKEAFSSNIFLGGVRL 701
              DI +  L + + D++  S N F+G +R+
Sbjct: 166 TDDDITHKVLRIAVCDEDKLSHNEFIGEIRV 196


>gi|238550198 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  108 bits (269), Expect = 2e-23
 Identities = 89/322 (27%), Positives = 137/322 (42%), Gaps = 53/322 (16%)

Query: 420 TGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSR 479
           +G+ G     G I   + Y Y +  L + +    +L   D     +D YVK YLLPD  R
Sbjct: 291 SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGF-SDPYVKIYLLPD--R 347

Query: 480 NNKRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDS 538
             K +TK+   T NP FNET ++++   +L  R L  SV+ +DRF R+  +G+V +    
Sbjct: 348 KKKFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLL 407

Query: 539 WNFENPTDE--WFVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFK 596
              E P D   W  +        D+     GEL   L Y+P                   
Sbjct: 408 ELAEQPPDRPLWRDIVEGGSEKADL-----GELNFSLCYLP------------------- 443

Query: 597 KGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKS 656
                     + G L V I +A NL A+   G SD +VK  L+ +  +  K KT + K +
Sbjct: 444 ----------TAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNT 493

Query: 657 VNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWM 716
           +NP +N   +F  + P+ ++NV L + + D +    N  +G  R+   +   HG+     
Sbjct: 494 LNPTYNEALVFD-VAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGR----- 547

Query: 717 DSQGEEQRLWQKMANNPGTPFE 738
                    W +M  NP  P E
Sbjct: 548 -------EHWAEMLANPRKPVE 562


>gi|238550196 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  108 bits (269), Expect = 2e-23
 Identities = 89/322 (27%), Positives = 137/322 (42%), Gaps = 53/322 (16%)

Query: 420 TGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSR 479
           +G+ G     G I   + Y Y +  L + +    +L   D     +D YVK YLLPD  R
Sbjct: 291 SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGF-SDPYVKIYLLPD--R 347

Query: 480 NNKRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDS 538
             K +TK+   T NP FNET ++++   +L  R L  SV+ +DRF R+  +G+V +    
Sbjct: 348 KKKFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLL 407

Query: 539 WNFENPTDE--WFVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFK 596
              E P D   W  +        D+     GEL   L Y+P                   
Sbjct: 408 ELAEQPPDRPLWRDIVEGGSEKADL-----GELNFSLCYLP------------------- 443

Query: 597 KGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKS 656
                     + G L V I +A NL A+   G SD +VK  L+ +  +  K KT + K +
Sbjct: 444 ----------TAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNT 493

Query: 657 VNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWM 716
           +NP +N   +F  + P+ ++NV L + + D +    N  +G  R+   +   HG+     
Sbjct: 494 LNPTYNEALVFD-VAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGR----- 547

Query: 717 DSQGEEQRLWQKMANNPGTPFE 738
                    W +M  NP  P E
Sbjct: 548 -------EHWAEMLANPRKPVE 562


>gi|14150054 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  108 bits (269), Expect = 2e-23
 Identities = 89/322 (27%), Positives = 137/322 (42%), Gaps = 53/322 (16%)

Query: 420 TGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSR 479
           +G+ G     G I   + Y Y +  L + +    +L   D     +D YVK YLLPD  R
Sbjct: 291 SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGF-SDPYVKIYLLPD--R 347

Query: 480 NNKRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDS 538
             K +TK+   T NP FNET ++++   +L  R L  SV+ +DRF R+  +G+V +    
Sbjct: 348 KKKFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLL 407

Query: 539 WNFENPTDE--WFVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFK 596
              E P D   W  +        D+     GEL   L Y+P                   
Sbjct: 408 ELAEQPPDRPLWRDIVEGGSEKADL-----GELNFSLCYLP------------------- 443

Query: 597 KGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKS 656
                     + G L V I +A NL A+   G SD +VK  L+ +  +  K KT + K +
Sbjct: 444 ----------TAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNT 493

Query: 657 VNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWM 716
           +NP +N   +F  + P+ ++NV L + + D +    N  +G  R+   +   HG+     
Sbjct: 494 LNPTYNEALVFD-VAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGR----- 547

Query: 717 DSQGEEQRLWQKMANNPGTPFE 738
                    W +M  NP  P E
Sbjct: 548 -------EHWAEMLANPRKPVE 562


>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
          Length = 694

 Score =  105 bits (262), Expect = 2e-22
 Identities = 86/278 (30%), Positives = 136/278 (48%), Gaps = 31/278 (11%)

Query: 466 DAYVKSYLLPDKSRNNKRKTK-IRTGTNPEFNETLKYT-ISHTQLETRTLQLSVWHYDRF 523
           D YVK +LLP  S++NK +TK +R   NP +NETL Y  I+   ++ +TL++SV   D+F
Sbjct: 429 DPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKF 488

Query: 524 GRNSFLGEVEIPFDSWNFENPTDEWFVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLM 583
           G N F+GE           N    + +   +V     I ++  G           EE  +
Sbjct: 489 GHNEFIGETRFSLKKLK-PNQRKNFNICLERV-----IPMKRAGTTGSARGMALYEEEQV 542

Query: 584 LPPEQLQGNKTFKKGKKKESPVIS---GGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLP 640
                ++     ++GK   S + S   GG++ V I    +L A+ + G SD FVK +L P
Sbjct: 543 ERVGDIE-----ERGKILVSLMYSTQQGGLI-VGIIRCVHLAAMDANGYSDPFVKLWLKP 596

Query: 641 DDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVR 700
           D  K  KHKT + KK++NP++N  F F  I   D+    L++++WD +   SN ++GG +
Sbjct: 597 DMGKKAKHKTQIKKKTLNPEFNEEF-FYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQ 655

Query: 701 LNSGSGVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFE 738
           L    G+S         ++GE  + W +   N     E
Sbjct: 656 L----GIS---------AKGERLKHWYECLKNKDKKIE 680



 Score = 80.1 bits (196), Expect = 7e-15
 Identities = 47/138 (34%), Positives = 75/138 (54%), Gaps = 4/138 (2%)

Query: 400 VPDADSDTTSLNSMMSVYSE--TGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAI 457
           +P   + TT     M++Y E      G+++  G+IL+ + Y  + GGL + +  C +LA 
Sbjct: 520 IPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAA 579

Query: 458 GDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLS 516
            D     +D +VK +L PD  +  K KT+I+  T NPEFNE   Y I H+ L  ++L +S
Sbjct: 580 MDANGY-SDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDIS 638

Query: 517 VWHYDRFGRNSFLGEVEI 534
           VW YD    N ++G  ++
Sbjct: 639 VWDYDIGKSNDYIGGCQL 656



 Score = 67.4 bits (163), Expect = 5e-11
 Identities = 32/92 (34%), Positives = 55/92 (59%)

Query: 611 LEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSGI 670
           L+  I +AK L  + S G +D +VK +LLP  SK+ K +T  ++ + NP WN T ++ GI
Sbjct: 409 LQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGI 468

Query: 671 HPQDIKNVCLELTIWDKEAFSSNIFLGGVRLN 702
             +D++   L +++ D++ F  N F+G  R +
Sbjct: 469 TDEDMQRKTLRISVCDEDKFGHNEFIGETRFS 500



 Score = 63.2 bits (152), Expect = 9e-10
 Identities = 66/275 (24%), Positives = 109/275 (39%), Gaps = 33/275 (12%)

Query: 13  LLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTQQEASRVCVHCHRNLG 72
           L D EKE+I  V+ R E ++++E +RI +L + L   ++       +    C+ C   LG
Sbjct: 50  LTDEEKEIINRVIARAEKMEEMEQERIGRLVDRLENMRK---NVAGDGVNRCILCGEQLG 106

Query: 73  LIFDRGDPCQACSLRVCRECRVAGPN---GSWKCTVCDKIAQLRIITGEWFFEEKAKRFK 129
           ++      C+ C   VC +C V   N     W C +C +  ++   +G WFF+   K+  
Sbjct: 107 MLGSACVVCEDCKKNVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQ-- 164

Query: 130 QVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAEKSDTSPVAGKKASHDGPKRK----- 184
              VL   +  +    + P   E  + EQ   + +    +P  G      GP +K     
Sbjct: 165 ---VLPQPMPIKKTKPQQP-VSEPAAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDP 220

Query: 185 ------GFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDL 238
                 G      R A+   + +   D   S S D  G    S +SP G  R ++  +  
Sbjct: 221 ASAPGRGNYGPPVRRASEARMSSSSRD---SESWDHSGGAGDSSRSPAGLRRANSVQASR 277

Query: 239 ----NDQEPGPRTPKSSRSNGVTPGTQSSPAPSTR 269
               + Q P P  P      G   G++  P P+ R
Sbjct: 278 PAPGSVQSPAPPQPGQP---GTPGGSRPGPGPAGR 309


>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
          Length = 690

 Score =  105 bits (262), Expect = 2e-22
 Identities = 86/278 (30%), Positives = 136/278 (48%), Gaps = 31/278 (11%)

Query: 466 DAYVKSYLLPDKSRNNKRKTK-IRTGTNPEFNETLKYT-ISHTQLETRTLQLSVWHYDRF 523
           D YVK +LLP  S++NK +TK +R   NP +NETL Y  I+   ++ +TL++SV   D+F
Sbjct: 425 DPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKF 484

Query: 524 GRNSFLGEVEIPFDSWNFENPTDEWFVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLM 583
           G N F+GE           N    + +   +V     I ++  G           EE  +
Sbjct: 485 GHNEFIGETRFSLKKLK-PNQRKNFNICLERV-----IPMKRAGTTGSARGMALYEEEQV 538

Query: 584 LPPEQLQGNKTFKKGKKKESPVIS---GGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLP 640
                ++     ++GK   S + S   GG++ V I    +L A+ + G SD FVK +L P
Sbjct: 539 ERVGDIE-----ERGKILVSLMYSTQQGGLI-VGIIRCVHLAAMDANGYSDPFVKLWLKP 592

Query: 641 DDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVR 700
           D  K  KHKT + KK++NP++N  F F  I   D+    L++++WD +   SN ++GG +
Sbjct: 593 DMGKKAKHKTQIKKKTLNPEFNEEF-FYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQ 651

Query: 701 LNSGSGVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFE 738
           L    G+S         ++GE  + W +   N     E
Sbjct: 652 L----GIS---------AKGERLKHWYECLKNKDKKIE 676



 Score = 80.1 bits (196), Expect = 7e-15
 Identities = 47/138 (34%), Positives = 75/138 (54%), Gaps = 4/138 (2%)

Query: 400 VPDADSDTTSLNSMMSVYSE--TGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAI 457
           +P   + TT     M++Y E      G+++  G+IL+ + Y  + GGL + +  C +LA 
Sbjct: 516 IPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAA 575

Query: 458 GDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLS 516
            D     +D +VK +L PD  +  K KT+I+  T NPEFNE   Y I H+ L  ++L +S
Sbjct: 576 MDANGY-SDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDIS 634

Query: 517 VWHYDRFGRNSFLGEVEI 534
           VW YD    N ++G  ++
Sbjct: 635 VWDYDIGKSNDYIGGCQL 652



 Score = 67.4 bits (163), Expect = 5e-11
 Identities = 32/92 (34%), Positives = 55/92 (59%)

Query: 611 LEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSGI 670
           L+  I +AK L  + S G +D +VK +LLP  SK+ K +T  ++ + NP WN T ++ GI
Sbjct: 405 LQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGI 464

Query: 671 HPQDIKNVCLELTIWDKEAFSSNIFLGGVRLN 702
             +D++   L +++ D++ F  N F+G  R +
Sbjct: 465 TDEDMQRKTLRISVCDEDKFGHNEFIGETRFS 496



 Score = 63.2 bits (152), Expect = 9e-10
 Identities = 66/275 (24%), Positives = 109/275 (39%), Gaps = 33/275 (12%)

Query: 13  LLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTQQEASRVCVHCHRNLG 72
           L D EKE+I  V+ R E ++++E +RI +L + L   ++       +    C+ C   LG
Sbjct: 46  LTDEEKEIINRVIARAEKMEEMEQERIGRLVDRLENMRK---NVAGDGVNRCILCGEQLG 102

Query: 73  LIFDRGDPCQACSLRVCRECRVAGPN---GSWKCTVCDKIAQLRIITGEWFFEEKAKRFK 129
           ++      C+ C   VC +C V   N     W C +C +  ++   +G WFF+   K+  
Sbjct: 103 MLGSACVVCEDCKKNVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQ-- 160

Query: 130 QVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAEKSDTSPVAGKKASHDGPKRK----- 184
              VL   +  +    + P   E  + EQ   + +    +P  G      GP +K     
Sbjct: 161 ---VLPQPMPIKKTKPQQP-VSEPAAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDP 216

Query: 185 ------GFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDL 238
                 G      R A+   + +   D   S S D  G    S +SP G  R ++  +  
Sbjct: 217 ASAPGRGNYGPPVRRASEARMSSSSRD---SESWDHSGGAGDSSRSPAGLRRANSVQASR 273

Query: 239 ----NDQEPGPRTPKSSRSNGVTPGTQSSPAPSTR 269
               + Q P P  P      G   G++  P P+ R
Sbjct: 274 PAPGSVQSPAPPQPGQP---GTPGGSRPGPGPAGR 305


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.130    0.376 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,821,040
Number of Sequences: 37866
Number of extensions: 1441452
Number of successful extensions: 6013
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 103
Number of HSP's successfully gapped in prelim test: 208
Number of HSP's that attempted gapping in prelim test: 5111
Number of HSP's gapped (non-prelim): 815
length of query: 752
length of database: 18,247,518
effective HSP length: 110
effective length of query: 642
effective length of database: 14,082,258
effective search space: 9040809636
effective search space used: 9040809636
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.