Guide to the Human Genome
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Search of human proteins with 120952755

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|120952755 sperm acrosome associated 5B [Homo sapiens]
         (159 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|118498373 sperm acrosome associated 5 [Homo sapiens]               349   5e-97
gi|120952755 sperm acrosome associated 5B [Homo sapiens]              349   5e-97
gi|27777653 sperm acrosome associated 3 [Homo sapiens]                151   3e-37
gi|9966905 lysozyme-like 6 [Homo sapiens]                             149   1e-36
gi|73390143 lysozyme-like 1 [Homo sapiens]                            149   1e-36
gi|73088987 lysozyme-like 2 [Homo sapiens]                            145   1e-35
gi|4557894 lysozyme precursor [Homo sapiens]                          144   3e-35
gi|21389465 lysozyme-like 4 [Homo sapiens]                            112   2e-25
gi|4504947 lactalbumin, alpha- precursor [Homo sapiens]                82   3e-16
gi|108773804 Fraser syndrome 1 [Homo sapiens]                          31   0.51 
gi|4507467 transforming growth factor, beta-induced, 68kDa precu...    28   3.3  
gi|156416009 regulator of G-protein signalling 16 [Homo sapiens]       28   3.3  
gi|14149987 WD repeat domain 24 [Homo sapiens]                         28   4.3  
gi|187960079 MAD2 homolog [Homo sapiens]                               27   9.6  
gi|187960073 MAD2 homolog [Homo sapiens]                               27   9.6  
gi|31542747 catechol-O-methyltransferase domain containing 1 [Ho...    27   9.6  

>gi|118498373 sperm acrosome associated 5 [Homo sapiens]
          Length = 159

 Score =  349 bits (896), Expect = 5e-97
 Identities = 159/159 (100%), Positives = 159/159 (100%)

Query: 1   MKAWGTVVVTLATLMVVTVDAKIYERCELAARLERAGLNGYKGYGVGDWLCMAHYESGFD 60
           MKAWGTVVVTLATLMVVTVDAKIYERCELAARLERAGLNGYKGYGVGDWLCMAHYESGFD
Sbjct: 1   MKAWGTVVVTLATLMVVTVDAKIYERCELAARLERAGLNGYKGYGVGDWLCMAHYESGFD 60

Query: 61  TAFVDHNPDGSSEYGIFQLNSAWWCDNGITPTKNLCHMDCHDLLNRHILDDIRCAKQIVS 120
           TAFVDHNPDGSSEYGIFQLNSAWWCDNGITPTKNLCHMDCHDLLNRHILDDIRCAKQIVS
Sbjct: 61  TAFVDHNPDGSSEYGIFQLNSAWWCDNGITPTKNLCHMDCHDLLNRHILDDIRCAKQIVS 120

Query: 121 SQNGLSAWTSWRLHCSGHDLSEWLKGCDMHVKIDPKIHP 159
           SQNGLSAWTSWRLHCSGHDLSEWLKGCDMHVKIDPKIHP
Sbjct: 121 SQNGLSAWTSWRLHCSGHDLSEWLKGCDMHVKIDPKIHP 159


>gi|120952755 sperm acrosome associated 5B [Homo sapiens]
          Length = 159

 Score =  349 bits (896), Expect = 5e-97
 Identities = 159/159 (100%), Positives = 159/159 (100%)

Query: 1   MKAWGTVVVTLATLMVVTVDAKIYERCELAARLERAGLNGYKGYGVGDWLCMAHYESGFD 60
           MKAWGTVVVTLATLMVVTVDAKIYERCELAARLERAGLNGYKGYGVGDWLCMAHYESGFD
Sbjct: 1   MKAWGTVVVTLATLMVVTVDAKIYERCELAARLERAGLNGYKGYGVGDWLCMAHYESGFD 60

Query: 61  TAFVDHNPDGSSEYGIFQLNSAWWCDNGITPTKNLCHMDCHDLLNRHILDDIRCAKQIVS 120
           TAFVDHNPDGSSEYGIFQLNSAWWCDNGITPTKNLCHMDCHDLLNRHILDDIRCAKQIVS
Sbjct: 61  TAFVDHNPDGSSEYGIFQLNSAWWCDNGITPTKNLCHMDCHDLLNRHILDDIRCAKQIVS 120

Query: 121 SQNGLSAWTSWRLHCSGHDLSEWLKGCDMHVKIDPKIHP 159
           SQNGLSAWTSWRLHCSGHDLSEWLKGCDMHVKIDPKIHP
Sbjct: 121 SQNGLSAWTSWRLHCSGHDLSEWLKGCDMHVKIDPKIHP 159


>gi|27777653 sperm acrosome associated 3 [Homo sapiens]
          Length = 215

 Score =  151 bits (381), Expect = 3e-37
 Identities = 65/141 (46%), Positives = 92/141 (65%)

Query: 8   VVTLATLMVVTVDAKIYERCELAARLERAGLNGYKGYGVGDWLCMAHYESGFDTAFVDHN 67
           +V L + ++ + +AK+Y RCELA  L   GL+GY+GY + DW+C+A++ SGF+ A +D+ 
Sbjct: 74  LVCLLSCLLPSSEAKLYGRCELARVLHDFGLDGYRGYSLADWVCLAYFTSGFNAAALDYE 133

Query: 68  PDGSSEYGIFQLNSAWWCDNGITPTKNLCHMDCHDLLNRHILDDIRCAKQIVSSQNGLSA 127
            DGS+  GIFQ+NS  WC N      N+C M C DLLN ++ D + CA +I     GL  
Sbjct: 134 ADGSTNNGIFQINSRRWCSNLTPNVPNVCRMYCSDLLNPNLKDTVICAMKITQEPQGLGY 193

Query: 128 WTSWRLHCSGHDLSEWLKGCD 148
           W +WR HC G DL+EW+ GCD
Sbjct: 194 WEAWRHHCQGKDLTEWVDGCD 214


>gi|9966905 lysozyme-like 6 [Homo sapiens]
          Length = 148

 Score =  149 bits (375), Expect = 1e-36
 Identities = 63/141 (44%), Positives = 95/141 (67%)

Query: 7   VVVTLATLMVVTVDAKIYERCELAARLERAGLNGYKGYGVGDWLCMAHYESGFDTAFVDH 66
           +++ L +  +    A +  RC+LA  L+   L+G++GY + DWLC+A  ES F+ + ++ 
Sbjct: 5   LLIYLVSSFLALNQASLISRCDLAQVLQLEDLDGFEGYSLSDWLCLAFVESKFNISKINE 64

Query: 67  NPDGSSEYGIFQLNSAWWCDNGITPTKNLCHMDCHDLLNRHILDDIRCAKQIVSSQNGLS 126
           N DGS +YG+FQ+NS +WC++  + ++NLCH+DC DLLN ++L  I CAK+IVS   G++
Sbjct: 65  NADGSFDYGLFQINSHYWCNDYKSYSENLCHVDCQDLLNPNLLAGIHCAKRIVSGARGMN 124

Query: 127 AWTSWRLHCSGHDLSEWLKGC 147
            W  WRLHCSG  L  WL GC
Sbjct: 125 NWVEWRLHCSGRPLFYWLTGC 145


>gi|73390143 lysozyme-like 1 [Homo sapiens]
          Length = 194

 Score =  149 bits (375), Expect = 1e-36
 Identities = 68/149 (45%), Positives = 94/149 (63%), Gaps = 2/149 (1%)

Query: 1   MKAWGTVVVTLATLMVVTVDAKIYERCELAARLERAGLNGYKGYGVGDWLCMAHYESGFD 60
           MKA G  ++TL   +V   ++KIY RC+LA    RAGL+ Y G+ +G+W+CMA+YESG++
Sbjct: 47  MKAAG--ILTLIGCLVTGAESKIYTRCKLAKIFSRAGLDNYWGFSLGNWICMAYYESGYN 104

Query: 61  TAFVDHNPDGSSEYGIFQLNSAWWCDNGITPTKNLCHMDCHDLLNRHILDDIRCAKQIVS 120
           T       DGS +YGIFQ+NS  WC  G     N CH+ C  L+   + D I CA++IV 
Sbjct: 105 TTAQTVLDDGSIDYGIFQINSFAWCRRGKLKENNHCHVACSALITDDLTDAIICARKIVK 164

Query: 121 SQNGLSAWTSWRLHCSGHDLSEWLKGCDM 149
              G++ W  W+ HC G DLSEW KGC++
Sbjct: 165 ETQGMNYWQGWKKHCEGRDLSEWKKGCEV 193


>gi|73088987 lysozyme-like 2 [Homo sapiens]
          Length = 194

 Score =  145 bits (367), Expect = 1e-35
 Identities = 67/149 (44%), Positives = 93/149 (62%), Gaps = 2/149 (1%)

Query: 1   MKAWGTVVVTLATLMVVTVDAKIYERCELAARLERAGLNGYKGYGVGDWLCMAHYESGFD 60
           MKA G  ++TL   +V   ++KIY RC+LA    RAGL+ Y G+ +G+W+CMA+YESG++
Sbjct: 47  MKAAG--ILTLIGCLVTGAESKIYTRCKLAKIFSRAGLDNYWGFSLGNWICMAYYESGYN 104

Query: 61  TAFVDHNPDGSSEYGIFQLNSAWWCDNGITPTKNLCHMDCHDLLNRHILDDIRCAKQIVS 120
           T       DGS +YGIFQ+NS  WC  G     N CH+ C  L+   + D I CAK+IV 
Sbjct: 105 TTAQTVLDDGSIDYGIFQINSFAWCRRGKLKENNHCHVACSALVTDDLTDAIICAKKIVK 164

Query: 121 SQNGLSAWTSWRLHCSGHDLSEWLKGCDM 149
              G++ W  W+ HC G DLS+W K C++
Sbjct: 165 ETQGMNYWQGWKKHCEGRDLSDWKKDCEV 193


>gi|4557894 lysozyme precursor [Homo sapiens]
          Length = 148

 Score =  144 bits (363), Expect = 3e-35
 Identities = 61/143 (42%), Positives = 97/143 (67%), Gaps = 2/143 (1%)

Query: 7   VVVTLATLMVVTVDAKIYERCELAARLERAGLNGYKGYGVGDWLCMAHYESGFDTAFVDH 66
           ++V    L+ VTV  K++ERCELA  L+R G++GY+G  + +W+C+A +ESG++T   ++
Sbjct: 4   LIVLGLVLLSVTVQGKVFERCELARTLKRLGMDGYRGISLANWMCLAKWESGYNTRATNY 63

Query: 67  NP-DGSSEYGIFQLNSAWWCDNGITP-TKNLCHMDCHDLLNRHILDDIRCAKQIVSSQNG 124
           N  D S++YGIFQ+NS +WC++G TP   N CH+ C  LL  +I D + CAK++V    G
Sbjct: 64  NAGDRSTDYGIFQINSRYWCNDGKTPGAVNACHLSCSALLQDNIADAVACAKRVVRDPQG 123

Query: 125 LSAWTSWRLHCSGHDLSEWLKGC 147
           + AW +WR  C   D+ ++++GC
Sbjct: 124 IRAWVAWRNRCQNRDVRQYVQGC 146


>gi|21389465 lysozyme-like 4 [Homo sapiens]
          Length = 146

 Score =  112 bits (279), Expect = 2e-25
 Identities = 58/152 (38%), Positives = 93/152 (61%), Gaps = 9/152 (5%)

Query: 1   MKAWGTVVVTLATLMVVTVDAKIYERCELAARLERAGLNGYKGYGVGDWLCMAHYESGFD 60
           MKA  +VV++L   +VV   A I  RC +A +L   GL+ ++GY + +W+C+A++ES F+
Sbjct: 1   MKA--SVVLSLLGYLVVPSGAYILGRCTVAKKLHDGGLDYFEGYSLENWVCLAYFESKFN 58

Query: 61  T-AFVDHNPDGSSEYGIFQLNSAWWC-DNGITPTKNLCHMDCHDLLNRHILDDIRCAKQI 118
             A  ++  +G + +G+FQ+  + WC D+G    +N CHM C  LLN ++   I+CAK I
Sbjct: 59  PMAIYENTREGYTGFGLFQMRGSDWCGDHG----RNRCHMSCSALLNPNLEKTIKCAKTI 114

Query: 119 VSSQNGLSAWTSWRLHCSGHD-LSEWLKGCDM 149
           V  + G+ AW +W  +C   D L+ WL GC +
Sbjct: 115 VKGKEGMGAWPTWSRYCQYSDTLARWLDGCKL 146


>gi|4504947 lactalbumin, alpha- precursor [Homo sapiens]
          Length = 142

 Score = 81.6 bits (200), Expect = 3e-16
 Identities = 44/139 (31%), Positives = 80/139 (57%), Gaps = 6/139 (4%)

Query: 7   VVVTLATLMVVTVDAKIYERCELAARLERAGLNGYKGYGVGDWLCMAHYESGFDTAFVDH 66
           V + L  ++   + AK + +CEL+  L+   ++GY G  + + +C   + SG+DT  +  
Sbjct: 5   VPLFLVGILFPAILAKQFTKCELSQLLK--DIDGYGGIALPELICTMFHTSGYDTQAIVE 62

Query: 67  NPDGSSEYGIFQLNSAWWCDNGITP-TKNLCHMDCHDLLNRHILDDIRCAKQIVSSQNGL 125
           N + S+EYG+FQ+++  WC +   P ++N+C + C   L+  I DDI CAK+I+  + G+
Sbjct: 63  NNE-STEYGLFQISNKLWCKSSQVPQSRNICDISCDKFLDDDITDDIMCAKKILDIK-GI 120

Query: 126 SAWTSWRLHCSGHDLSEWL 144
             W + +  C+   L +WL
Sbjct: 121 DYWLAHKALCT-EKLEQWL 138


>gi|108773804 Fraser syndrome 1 [Homo sapiens]
          Length = 4011

 Score = 30.8 bits (68), Expect = 0.51
 Identities = 18/64 (28%), Positives = 28/64 (43%), Gaps = 3/64 (4%)

Query: 77   FQLNSAWWCDNGITPTKNLCHMDCHDLLNRHILDDIRCAKQIVSS---QNGLSAWTSWRL 133
            F  N+   CD   +        DC   ++ ++L D  C +Q +SS    +GL    S+ L
Sbjct: 950  FSTNTCKECDWSCSACSGPLKTDCLQCMDGYVLQDGACVEQCLSSFYQDSGLCKCDSYCL 1009

Query: 134  HCSG 137
             C G
Sbjct: 1010 QCQG 1013


>gi|4507467 transforming growth factor, beta-induced, 68kDa
           precursor [Homo sapiens]
          Length = 683

 Score = 28.1 bits (61), Expect = 3.3
 Identities = 19/44 (43%), Positives = 24/44 (54%), Gaps = 7/44 (15%)

Query: 102 DLLNRHILDDIRCAKQIVSSQNGLSA----WTSWRLHCSGHDLS 141
           DLLN HIL    CA+ IV+   GLS      T+  + CSG  L+
Sbjct: 305 DLLNNHILKSAMCAEAIVA---GLSVETLEGTTLEVGCSGDMLT 345


>gi|156416009 regulator of G-protein signalling 16 [Homo sapiens]
          Length = 202

 Score = 28.1 bits (61), Expect = 3.3
 Identities = 26/102 (25%), Positives = 47/102 (46%), Gaps = 8/102 (7%)

Query: 57  SGFDTAFVDHNPDGSSEYGIFQLNSAWWCDNGITPTKNLCHMDCHDLLNRHILDDIRCAK 116
           + F T  ++   +  +  GIF   S   CD G   T        H   NR+  +D+   +
Sbjct: 6   AAFPTTCLERAKEFKTRLGIFLHKSELGCDTG--STGKFEWGSKHSKENRNFSEDVLGWR 63

Query: 117 Q----IVSSQNGLSAWTSW-RLHCSGHDLSEWLKGCDMHVKI 153
           +    ++SS+NG++A+ ++ +   S  +L  WL  C+   KI
Sbjct: 64  ESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWL-ACEEFKKI 104


>gi|14149987 WD repeat domain 24 [Homo sapiens]
          Length = 790

 Score = 27.7 bits (60), Expect = 4.3
 Identities = 14/39 (35%), Positives = 18/39 (46%), Gaps = 6/39 (15%)

Query: 65  DHNPDGSSEYGIFQLNSAW------WCDNGITPTKNLCH 97
           DHN   + E G  Q+   W      +C  G+ PT NL H
Sbjct: 431 DHNAKVARELGRNQVAQTWTMLRIIYCSPGLVPTANLNH 469


>gi|187960079 MAD2 homolog [Homo sapiens]
          Length = 211

 Score = 26.6 bits (57), Expect = 9.6
 Identities = 9/26 (34%), Positives = 15/26 (57%)

Query: 98  MDCHDLLNRHILDDIRCAKQIVSSQN 123
           M CH  LN++I D + C K ++   +
Sbjct: 54  MSCHPELNQYIQDTLHCVKPLLEKND 79


>gi|187960073 MAD2 homolog [Homo sapiens]
          Length = 211

 Score = 26.6 bits (57), Expect = 9.6
 Identities = 9/26 (34%), Positives = 15/26 (57%)

Query: 98  MDCHDLLNRHILDDIRCAKQIVSSQN 123
           M CH  LN++I D + C K ++   +
Sbjct: 54  MSCHPELNQYIQDTLHCVKPLLEKND 79


>gi|31542747 catechol-O-methyltransferase domain containing 1 [Homo
           sapiens]
          Length = 262

 Score = 26.6 bits (57), Expect = 9.6
 Identities = 23/90 (25%), Positives = 33/90 (36%), Gaps = 11/90 (12%)

Query: 48  DWLCMAHYESGFDTAFVDHNPDGSSEY-----------GIFQLNSAWWCDNGITPTKNLC 96
           D L  A     FD A VD + +  S Y           GI  +    W    + P K   
Sbjct: 168 DELLAAGEAGTFDVAVVDADKENCSAYYERCLQLLRPGGILAVLRVLWRGKVLQPPKGDV 227

Query: 97  HMDCHDLLNRHILDDIRCAKQIVSSQNGLS 126
             +C   LN  I  D+R    ++   +GL+
Sbjct: 228 AAECVRNLNERIRRDVRVYISLLPLGDGLT 257


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.137    0.473 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,335,054
Number of Sequences: 37866
Number of extensions: 260997
Number of successful extensions: 424
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 407
Number of HSP's gapped (non-prelim): 16
length of query: 159
length of database: 18,247,518
effective HSP length: 94
effective length of query: 65
effective length of database: 14,688,114
effective search space: 954727410
effective search space used: 954727410
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 57 (26.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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