BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|120433602 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 18 [Homo sapiens] (2138 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|120433602 calcium channel, voltage-dependent, L type, alpha 1... 4281 0.0 gi|193788528 calcium channel, voltage-dependent, L type, alpha 1... 4269 0.0 gi|193788526 calcium channel, voltage-dependent, L type, alpha 1... 4269 0.0 gi|193788732 calcium channel, voltage-dependent, L type, alpha 1... 4266 0.0 gi|193788542 calcium channel, voltage-dependent, L type, alpha 1... 4264 0.0 gi|193788540 calcium channel, voltage-dependent, L type, alpha 1... 4260 0.0 gi|193788728 calcium channel, voltage-dependent, L type, alpha 1... 4256 0.0 gi|193788724 calcium channel, voltage-dependent, L type, alpha 1... 4254 0.0 gi|193788530 calcium channel, voltage-dependent, L type, alpha 1... 4253 0.0 gi|193794828 calcium channel, voltage-dependent, L type, alpha 1... 4248 0.0 gi|193788544 calcium channel, voltage-dependent, L type, alpha 1... 4248 0.0 gi|193788730 calcium channel, voltage-dependent, L type, alpha 1... 4247 0.0 gi|193788536 calcium channel, voltage-dependent, L type, alpha 1... 4247 0.0 gi|193788538 calcium channel, voltage-dependent, L type, alpha 1... 4244 0.0 gi|193788532 calcium channel, voltage-dependent, L type, alpha 1... 4236 0.0 gi|193788720 calcium channel, voltage-dependent, L type, alpha 1... 4236 0.0 gi|193788548 calcium channel, voltage-dependent, L type, alpha 1... 4232 0.0 gi|193794832 calcium channel, voltage-dependent, L type, alpha 1... 4232 0.0 gi|193788534 calcium channel, voltage-dependent, L type, alpha 1... 4220 0.0 gi|193794830 calcium channel, voltage-dependent, L type, alpha 1... 4217 0.0 gi|192807298 calcium channel, voltage-dependent, L type, alpha 1... 2746 0.0 gi|192807300 calcium channel, voltage-dependent, L type, alpha 1... 2744 0.0 gi|4502527 calcium channel, voltage-dependent, L type, alpha 1D ... 2744 0.0 gi|53832007 calcium channel, voltage-dependent, L type, alpha 1F... 2294 0.0 gi|110349767 calcium channel, voltage-dependent, L type, alpha 1... 2286 0.0 gi|187828880 calcium channel, alpha 1A subunit isoform 3 [Homo s... 776 0.0 gi|4502523 calcium channel, voltage-dependent, N type, alpha 1B ... 768 0.0 gi|187828892 calcium channel, alpha 1A subunit isoform 4 [Homo s... 767 0.0 gi|53832005 calcium channel, voltage-dependent, R type, alpha 1E... 745 0.0 gi|38505290 voltage-dependent calcium channel alpha 1G subunit i... 332 2e-90 >gi|120433602 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 18 [Homo sapiens] Length = 2138 Score = 4281 bits (11102), Expect = 0.0 Identities = 2138/2138 (100%), Positives = 2138/2138 (100%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEEN 1320 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEEN Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEEN 1320 Query: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ Sbjct: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 Query: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS Sbjct: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 Query: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI Sbjct: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 Query: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA Sbjct: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 Query: 1561 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA 1620 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA Sbjct: 1561 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA 1620 Query: 1621 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD 1680 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD Sbjct: 1621 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD 1680 Query: 1681 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT 1740 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT Sbjct: 1681 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT 1740 Query: 1741 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP 1800 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP Sbjct: 1741 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP 1800 Query: 1801 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS 1860 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS Sbjct: 1801 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS 1860 Query: 1861 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL 1920 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL Sbjct: 1861 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL 1920 Query: 1921 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS 1980 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS Sbjct: 1921 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS 1980 Query: 1981 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV 2040 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV Sbjct: 1981 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV 2040 Query: 2041 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC 2100 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC Sbjct: 2041 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC 2100 Query: 2101 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2101 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 >gi|193788528 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 8 [Homo sapiens] Length = 2157 Score = 4269 bits (11072), Expect = 0.0 Identities = 2138/2157 (99%), Positives = 2138/2157 (99%), Gaps = 19/2157 (0%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEEN 1320 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEEN Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEEN 1320 Query: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ Sbjct: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 Query: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS Sbjct: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 Query: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI Sbjct: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 Query: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA Sbjct: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 Query: 1561 TLFALVRTALRIKTE-------------------GNLEQANEELRAIIKKIWKRTSMKLL 1601 TLFALVRTALRIKTE GNLEQANEELRAIIKKIWKRTSMKLL Sbjct: 1561 TLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLEQANEELRAIIKKIWKRTSMKLL 1620 Query: 1602 DQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDI 1661 DQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDI Sbjct: 1621 DQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDI 1680 Query: 1662 GPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQT 1721 GPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQT Sbjct: 1681 GPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQT 1740 Query: 1722 FTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRP 1781 FTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRP Sbjct: 1741 FTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRP 1800 Query: 1782 AGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKM 1841 AGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKM Sbjct: 1801 AGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKM 1860 Query: 1842 NHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHL 1901 NHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHL Sbjct: 1861 NHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHL 1920 Query: 1902 ECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGS 1961 ECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGS Sbjct: 1921 ECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGS 1980 Query: 1962 RGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQ 2021 RGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQ Sbjct: 1981 RGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQ 2040 Query: 2022 AGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNI 2081 AGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNI Sbjct: 2041 AGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNI 2100 Query: 2082 LSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 LSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2101 LSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2157 >gi|193788526 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 6 [Homo sapiens] Length = 2158 Score = 4269 bits (11071), Expect = 0.0 Identities = 2138/2158 (99%), Positives = 2138/2158 (99%), Gaps = 20/2158 (0%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALK--------- 951 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALK Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVF 960 Query: 952 -----------MTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL 1000 MTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL Sbjct: 961 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL 1020 Query: 1001 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD 1060 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD Sbjct: 1021 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD 1080 Query: 1061 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL 1120 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL Sbjct: 1081 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL 1140 Query: 1121 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC 1180 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC Sbjct: 1141 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC 1200 Query: 1181 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH 1240 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH Sbjct: 1201 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH 1260 Query: 1241 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAI 1300 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAI Sbjct: 1261 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAI 1320 Query: 1301 TEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL 1360 TEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL Sbjct: 1321 TEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL 1380 Query: 1361 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD 1420 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD Sbjct: 1381 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD 1440 Query: 1421 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD 1480 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD Sbjct: 1441 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD 1500 Query: 1481 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC 1540 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC Sbjct: 1501 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC 1560 Query: 1541 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKL 1600 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKL Sbjct: 1561 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKL 1620 Query: 1601 LDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHD 1660 LDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHD Sbjct: 1621 LDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHD 1680 Query: 1661 IGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQ 1720 IGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQ Sbjct: 1681 IGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQ 1740 Query: 1721 TFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPR 1780 TFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPR Sbjct: 1741 TFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPR 1800 Query: 1781 PAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVK 1840 PAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVK Sbjct: 1801 PAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVK 1860 Query: 1841 MNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFH 1900 MNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFH Sbjct: 1861 MNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFH 1920 Query: 1901 LECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPG 1960 LECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPG Sbjct: 1921 LECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPG 1980 Query: 1961 SRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPS 2020 SRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPS Sbjct: 1981 SRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPS 2040 Query: 2021 QAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADN 2080 QAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADN Sbjct: 2041 QAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADN 2100 Query: 2081 ILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 ILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2101 ILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2158 >gi|193788732 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 5 [Homo sapiens] Length = 2166 Score = 4266 bits (11063), Expect = 0.0 Identities = 2138/2166 (98%), Positives = 2138/2166 (98%), Gaps = 28/2166 (1%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPK----------------------------HYFCDAWNTFDALIVV 1292 LFTVEMILKLIAFKPK HYFCDAWNTFDALIVV Sbjct: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVV 1320 Query: 1293 GSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1352 GSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT Sbjct: 1321 GSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1380 Query: 1353 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1412 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC Sbjct: 1381 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1440 Query: 1413 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1472 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV Sbjct: 1441 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1500 Query: 1473 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1532 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK Sbjct: 1501 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1560 Query: 1533 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI 1592 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI Sbjct: 1561 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI 1620 Query: 1593 WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ 1652 WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ Sbjct: 1621 WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ 1680 Query: 1653 AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS 1712 AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS Sbjct: 1681 AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS 1740 Query: 1713 DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN 1772 DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN Sbjct: 1741 DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN 1800 Query: 1773 TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS 1832 TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS Sbjct: 1801 TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS 1860 Query: 1833 QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS 1892 QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS Sbjct: 1861 QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS 1920 Query: 1893 LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF 1952 LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF Sbjct: 1921 LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF 1980 Query: 1953 ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR 2012 ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR Sbjct: 1981 ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR 2040 Query: 2013 PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE 2072 PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE Sbjct: 2041 PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE 2100 Query: 2073 EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR 2132 EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR Sbjct: 2101 EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR 2160 Query: 2133 VYVSSL 2138 VYVSSL Sbjct: 2161 VYVSSL 2166 >gi|193788542 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 17 [Homo sapiens] Length = 2138 Score = 4264 bits (11060), Expect = 0.0 Identities = 2131/2138 (99%), Positives = 2133/2138 (99%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL D VFT+IFT+EI LKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEEN 1320 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEEN Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEEN 1320 Query: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ Sbjct: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 Query: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS Sbjct: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 Query: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI Sbjct: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 Query: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA Sbjct: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 Query: 1561 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA 1620 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA Sbjct: 1561 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA 1620 Query: 1621 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD 1680 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD Sbjct: 1621 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD 1680 Query: 1681 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT 1740 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT Sbjct: 1681 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT 1740 Query: 1741 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP 1800 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP Sbjct: 1741 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP 1800 Query: 1801 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS 1860 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS Sbjct: 1801 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS 1860 Query: 1861 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL 1920 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL Sbjct: 1861 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL 1920 Query: 1921 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS 1980 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS Sbjct: 1921 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS 1980 Query: 1981 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV 2040 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV Sbjct: 1981 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV 2040 Query: 2041 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC 2100 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC Sbjct: 2041 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC 2100 Query: 2101 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2101 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 >gi|193788540 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 16 [Homo sapiens] Length = 2138 Score = 4260 bits (11048), Expect = 0.0 Identities = 2126/2138 (99%), Positives = 2131/2138 (99%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEEN 1320 LFTVEMILKLIAFKPK YF D WN FD LIV+GSI+D+ ++E NPAEHTQCSPSMNAEEN Sbjct: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEEN 1320 Query: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ Sbjct: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 Query: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS Sbjct: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 Query: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI Sbjct: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 Query: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA Sbjct: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 Query: 1561 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA 1620 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA Sbjct: 1561 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA 1620 Query: 1621 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD 1680 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD Sbjct: 1621 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD 1680 Query: 1681 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT 1740 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT Sbjct: 1681 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT 1740 Query: 1741 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP 1800 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP Sbjct: 1741 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP 1800 Query: 1801 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS 1860 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS Sbjct: 1801 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS 1860 Query: 1861 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL 1920 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL Sbjct: 1861 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL 1920 Query: 1921 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS 1980 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS Sbjct: 1921 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS 1980 Query: 1981 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV 2040 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV Sbjct: 1981 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV 2040 Query: 2041 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC 2100 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC Sbjct: 2041 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC 2100 Query: 2101 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2101 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 >gi|193788728 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 3 [Homo sapiens] Length = 2179 Score = 4256 bits (11039), Expect = 0.0 Identities = 2138/2179 (98%), Positives = 2138/2179 (98%), Gaps = 41/2179 (1%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSM----- 1315 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSM Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMGPSCS 1320 Query: 1316 -----------------NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ 1358 NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ Sbjct: 1321 HPPLAVLTAPPVADGFQNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ 1380 Query: 1359 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW 1418 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW Sbjct: 1381 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW 1440 Query: 1419 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN 1478 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN Sbjct: 1441 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN 1500 Query: 1479 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV 1538 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV Sbjct: 1501 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV 1560 Query: 1539 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE-------------------GNLE 1579 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE GNLE Sbjct: 1561 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLE 1620 Query: 1580 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL 1639 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL Sbjct: 1621 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL 1680 Query: 1640 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA 1699 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA Sbjct: 1681 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA 1740 Query: 1700 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS 1759 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS Sbjct: 1741 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS 1800 Query: 1760 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR 1819 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR Sbjct: 1801 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR 1860 Query: 1820 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI 1879 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI Sbjct: 1861 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI 1920 Query: 1880 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL 1939 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL Sbjct: 1921 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL 1980 Query: 1940 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT 1999 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT Sbjct: 1981 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT 2040 Query: 2000 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT 2059 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT Sbjct: 2041 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT 2100 Query: 2060 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA 2119 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA Sbjct: 2101 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA 2160 Query: 2120 RGRPSEEELQDSRVYVSSL 2138 RGRPSEEELQDSRVYVSSL Sbjct: 2161 RGRPSEEELQDSRVYVSSL 2179 >gi|193788724 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 2 [Homo sapiens] Length = 2186 Score = 4254 bits (11032), Expect = 0.0 Identities = 2138/2186 (97%), Positives = 2138/2186 (97%), Gaps = 48/2186 (2%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALK--------- 951 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALK Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVF 960 Query: 952 -----------MTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL 1000 MTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL Sbjct: 961 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL 1020 Query: 1001 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD 1060 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD Sbjct: 1021 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD 1080 Query: 1061 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL 1120 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL Sbjct: 1081 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL 1140 Query: 1121 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC 1180 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC Sbjct: 1141 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC 1200 Query: 1181 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH 1240 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH Sbjct: 1201 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH 1260 Query: 1241 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPK------------------------ 1276 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPK Sbjct: 1261 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL 1320 Query: 1277 ----HYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR 1332 HYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR Sbjct: 1321 SETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR 1380 Query: 1333 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE 1392 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE Sbjct: 1381 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE 1440 Query: 1393 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA 1452 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA Sbjct: 1441 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA 1500 Query: 1453 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI 1512 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI Sbjct: 1501 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI 1560 Query: 1513 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI 1572 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI Sbjct: 1561 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI 1620 Query: 1573 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK 1632 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK Sbjct: 1621 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK 1680 Query: 1633 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE 1692 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE Sbjct: 1681 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE 1740 Query: 1693 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST 1752 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST Sbjct: 1741 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST 1800 Query: 1753 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS 1812 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS Sbjct: 1801 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS 1860 Query: 1813 SNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLP 1872 SNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLP Sbjct: 1861 SNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLP 1920 Query: 1873 EEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAV 1932 EEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAV Sbjct: 1921 EEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAV 1980 Query: 1933 AGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHC 1992 AGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHC Sbjct: 1981 AGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHC 2040 Query: 1993 GSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQD 2052 GSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQD Sbjct: 2041 GSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQD 2100 Query: 2053 PKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEE 2112 PKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEE Sbjct: 2101 PKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEE 2160 Query: 2113 DAGCVRARGRPSEEELQDSRVYVSSL 2138 DAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2161 DAGCVRARGRPSEEELQDSRVYVSSL 2186 >gi|193788530 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 9 [Homo sapiens] Length = 2157 Score = 4253 bits (11030), Expect = 0.0 Identities = 2131/2157 (98%), Positives = 2133/2157 (98%), Gaps = 19/2157 (0%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL D VFT+IFT+EI LKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEEN 1320 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEEN Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEEN 1320 Query: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ Sbjct: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 Query: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS Sbjct: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 Query: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI Sbjct: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 Query: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA Sbjct: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 Query: 1561 TLFALVRTALRIKTE-------------------GNLEQANEELRAIIKKIWKRTSMKLL 1601 TLFALVRTALRIKTE GNLEQANEELRAIIKKIWKRTSMKLL Sbjct: 1561 TLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLEQANEELRAIIKKIWKRTSMKLL 1620 Query: 1602 DQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDI 1661 DQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDI Sbjct: 1621 DQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDI 1680 Query: 1662 GPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQT 1721 GPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQT Sbjct: 1681 GPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQT 1740 Query: 1722 FTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRP 1781 FTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRP Sbjct: 1741 FTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRP 1800 Query: 1782 AGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKM 1841 AGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKM Sbjct: 1801 AGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKM 1860 Query: 1842 NHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHL 1901 NHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHL Sbjct: 1861 NHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHL 1920 Query: 1902 ECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGS 1961 ECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGS Sbjct: 1921 ECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGS 1980 Query: 1962 RGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQ 2021 RGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQ Sbjct: 1981 RGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQ 2040 Query: 2022 AGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNI 2081 AGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNI Sbjct: 2041 AGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNI 2100 Query: 2082 LSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 LSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2101 LSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2157 >gi|193794828 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 7 [Homo sapiens] Length = 2157 Score = 4248 bits (11018), Expect = 0.0 Identities = 2126/2157 (98%), Positives = 2131/2157 (98%), Gaps = 19/2157 (0%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEEN 1320 LFTVEMILKLIAFKPK YF D WN FD LIV+GSI+D+ ++E NPAEHTQCSPSMNAEEN Sbjct: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEEN 1320 Query: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ Sbjct: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 Query: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS Sbjct: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 Query: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI Sbjct: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 Query: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA Sbjct: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 Query: 1561 TLFALVRTALRIKTE-------------------GNLEQANEELRAIIKKIWKRTSMKLL 1601 TLFALVRTALRIKTE GNLEQANEELRAIIKKIWKRTSMKLL Sbjct: 1561 TLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLEQANEELRAIIKKIWKRTSMKLL 1620 Query: 1602 DQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDI 1661 DQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDI Sbjct: 1621 DQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDI 1680 Query: 1662 GPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQT 1721 GPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQT Sbjct: 1681 GPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQT 1740 Query: 1722 FTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRP 1781 FTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRP Sbjct: 1741 FTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRP 1800 Query: 1782 AGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKM 1841 AGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKM Sbjct: 1801 AGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKM 1860 Query: 1842 NHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHL 1901 NHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHL Sbjct: 1861 NHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHL 1920 Query: 1902 ECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGS 1961 ECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGS Sbjct: 1921 ECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGS 1980 Query: 1962 RGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQ 2021 RGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQ Sbjct: 1981 RGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQ 2040 Query: 2022 AGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNI 2081 AGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNI Sbjct: 2041 AGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNI 2100 Query: 2082 LSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 LSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2101 LSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2157 >gi|193788544 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 19 [Homo sapiens] Length = 2135 Score = 4248 bits (11017), Expect = 0.0 Identities = 2123/2138 (99%), Positives = 2128/2138 (99%), Gaps = 3/2138 (0%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIA AEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIA---AEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 357 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 358 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 417 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 418 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 477 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 478 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 537 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 538 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 597 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 598 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 657 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 658 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 717 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 718 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 777 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 778 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 837 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 838 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 897 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH Sbjct: 898 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 957 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 958 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1017 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1018 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1077 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1078 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1137 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1138 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1197 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1198 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1257 Query: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEEN 1320 LFTVEMILKLIAFKPK YF D WN FD LIV+GSI+D+ ++E NPAEHTQCSPSMNAEEN Sbjct: 1258 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEEN 1317 Query: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ Sbjct: 1318 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1377 Query: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS Sbjct: 1378 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1437 Query: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI Sbjct: 1438 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1497 Query: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA Sbjct: 1498 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1557 Query: 1561 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA 1620 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA Sbjct: 1558 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA 1617 Query: 1621 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD 1680 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD Sbjct: 1618 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD 1677 Query: 1681 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT 1740 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT Sbjct: 1678 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT 1737 Query: 1741 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP 1800 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP Sbjct: 1738 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP 1797 Query: 1801 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS 1860 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS Sbjct: 1798 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS 1857 Query: 1861 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL 1920 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL Sbjct: 1858 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL 1917 Query: 1921 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS 1980 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS Sbjct: 1918 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS 1977 Query: 1981 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV 2040 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV Sbjct: 1978 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV 2037 Query: 2041 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC 2100 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC Sbjct: 2038 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC 2097 Query: 2101 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2098 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2135 >gi|193788730 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 4 [Homo sapiens] Length = 2173 Score = 4247 bits (11014), Expect = 0.0 Identities = 2131/2173 (98%), Positives = 2133/2173 (98%), Gaps = 35/2173 (1%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL D VFT+IFT+EI LKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEEN 1320 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEEN Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEEN 1320 Query: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ Sbjct: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 Query: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS Sbjct: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 Query: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI Sbjct: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 Query: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA Sbjct: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 Query: 1561 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA 1620 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA Sbjct: 1561 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA 1620 Query: 1621 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD 1680 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD Sbjct: 1621 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD 1680 Query: 1681 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT 1740 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT Sbjct: 1681 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT 1740 Query: 1741 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP 1800 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP Sbjct: 1741 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP 1800 Query: 1801 AIRVQEVAWKLSSN-----------------------------------RCHSRESQAAM 1825 AIRVQEVAWKLSSN RCHSRESQAAM Sbjct: 1801 AIRVQEVAWKLSSNRERHVPMCEDLELRRDSGSAGTQAHCLLLRKANPSRCHSRESQAAM 1860 Query: 1826 AGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKR 1885 AGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKR Sbjct: 1861 AGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKR 1920 Query: 1886 GFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSP 1945 GFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSP Sbjct: 1921 GFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSP 1980 Query: 1946 ASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGS 2005 ASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGS Sbjct: 1981 ASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGS 2040 Query: 2006 SAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELAD 2065 SAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELAD Sbjct: 2041 SAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELAD 2100 Query: 2066 ACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSE 2125 ACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSE Sbjct: 2101 ACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSE 2160 Query: 2126 EELQDSRVYVSSL 2138 EELQDSRVYVSSL Sbjct: 2161 EELQDSRVYVSSL 2173 >gi|193788536 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 14 [Homo sapiens] Length = 2138 Score = 4247 bits (11014), Expect = 0.0 Identities = 2121/2138 (99%), Positives = 2129/2138 (99%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYW+ DA+G + PW+YFV+L+I GSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL D VFT+IFT+EI LKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEEN 1320 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEEN Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEEN 1320 Query: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ Sbjct: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 Query: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS Sbjct: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 Query: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI Sbjct: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 Query: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA Sbjct: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 Query: 1561 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA 1620 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA Sbjct: 1561 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA 1620 Query: 1621 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD 1680 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD Sbjct: 1621 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD 1680 Query: 1681 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT 1740 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT Sbjct: 1681 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT 1740 Query: 1741 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP 1800 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP Sbjct: 1741 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP 1800 Query: 1801 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS 1860 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS Sbjct: 1801 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS 1860 Query: 1861 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL 1920 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL Sbjct: 1861 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL 1920 Query: 1921 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS 1980 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS Sbjct: 1921 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS 1980 Query: 1981 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV 2040 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV Sbjct: 1981 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV 2040 Query: 2041 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC 2100 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC Sbjct: 2041 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC 2100 Query: 2101 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2101 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 >gi|193788538 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 15 [Homo sapiens] Length = 2138 Score = 4244 bits (11006), Expect = 0.0 Identities = 2119/2138 (99%), Positives = 2126/2138 (99%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL D VFT+IFT+EI LKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEEN 1320 LFTVEMILKLIAFKPK YF D WN FD LIV+GSI+D+ ++E NPAEHTQCSPSMNAEEN Sbjct: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEEN 1320 Query: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ Sbjct: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 Query: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS Sbjct: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 Query: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI Sbjct: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 Query: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA Sbjct: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 Query: 1561 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA 1620 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA Sbjct: 1561 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA 1620 Query: 1621 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD 1680 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD Sbjct: 1621 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD 1680 Query: 1681 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT 1740 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT Sbjct: 1681 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT 1740 Query: 1741 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP 1800 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP Sbjct: 1741 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP 1800 Query: 1801 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS 1860 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS Sbjct: 1801 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS 1860 Query: 1861 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL 1920 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL Sbjct: 1861 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL 1920 Query: 1921 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS 1980 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS Sbjct: 1921 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS 1980 Query: 1981 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV 2040 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV Sbjct: 1981 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV 2040 Query: 2041 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC 2100 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC Sbjct: 2041 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC 2100 Query: 2101 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2101 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 >gi|193788532 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 11 [Homo sapiens] Length = 2146 Score = 4236 bits (10987), Expect = 0.0 Identities = 2127/2157 (98%), Positives = 2127/2157 (98%), Gaps = 30/2157 (1%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEEN 1320 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVN NAEEN Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVN-----------NAEEN 1309 Query: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ Sbjct: 1310 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1369 Query: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS Sbjct: 1370 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1429 Query: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI Sbjct: 1430 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1489 Query: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA Sbjct: 1490 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1549 Query: 1561 TLFALVRTALRIKTE-------------------GNLEQANEELRAIIKKIWKRTSMKLL 1601 TLFALVRTALRIKTE GNLEQANEELRAIIKKIWKRTSMKLL Sbjct: 1550 TLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLEQANEELRAIIKKIWKRTSMKLL 1609 Query: 1602 DQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDI 1661 DQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDI Sbjct: 1610 DQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDI 1669 Query: 1662 GPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQT 1721 GPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQT Sbjct: 1670 GPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQT 1729 Query: 1722 FTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRP 1781 FTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRP Sbjct: 1730 FTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRP 1789 Query: 1782 AGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKM 1841 AGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKM Sbjct: 1790 AGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKM 1849 Query: 1842 NHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHL 1901 NHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHL Sbjct: 1850 NHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHL 1909 Query: 1902 ECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGS 1961 ECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGS Sbjct: 1910 ECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGS 1969 Query: 1962 RGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQ 2021 RGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQ Sbjct: 1970 RGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQ 2029 Query: 2022 AGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNI 2081 AGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNI Sbjct: 2030 AGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNI 2089 Query: 2082 LSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 LSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2090 LSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2146 >gi|193788720 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 1 [Homo sapiens] Length = 2221 Score = 4236 bits (10986), Expect = 0.0 Identities = 2138/2221 (96%), Positives = 2138/2221 (96%), Gaps = 83/2221 (3%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALK--------- 951 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALK Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVF 960 Query: 952 -----------MTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL 1000 MTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL Sbjct: 961 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL 1020 Query: 1001 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD 1060 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD Sbjct: 1021 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD 1080 Query: 1061 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL 1120 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL Sbjct: 1081 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL 1140 Query: 1121 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC 1180 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC Sbjct: 1141 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC 1200 Query: 1181 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH 1240 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH Sbjct: 1201 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH 1260 Query: 1241 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPK------------------------ 1276 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPK Sbjct: 1261 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL 1320 Query: 1277 ----HYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR 1332 HYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR Sbjct: 1321 SETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR 1380 Query: 1333 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE 1392 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE Sbjct: 1381 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE 1440 Query: 1393 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA 1452 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA Sbjct: 1441 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA 1500 Query: 1453 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI 1512 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI Sbjct: 1501 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI 1560 Query: 1513 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI 1572 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI Sbjct: 1561 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI 1620 Query: 1573 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK 1632 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK Sbjct: 1621 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK 1680 Query: 1633 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE 1692 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE Sbjct: 1681 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE 1740 Query: 1693 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST 1752 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST Sbjct: 1741 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST 1800 Query: 1753 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS 1812 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS Sbjct: 1801 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS 1860 Query: 1813 SN-----------------------------------RCHSRESQAAMAGQEETSQDETY 1837 SN RCHSRESQAAMAGQEETSQDETY Sbjct: 1861 SNRERHVPMCEDLELRRDSGSAGTQAHCLLLRKANPSRCHSRESQAAMAGQEETSQDETY 1920 Query: 1838 EVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRA 1897 EVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRA Sbjct: 1921 EVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRA 1980 Query: 1898 SFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPA 1957 SFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPA Sbjct: 1981 SFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPA 2040 Query: 1958 TPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLM 2017 TPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLM Sbjct: 2041 TPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLM 2100 Query: 2018 VPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESA 2077 VPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESA Sbjct: 2101 VPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESA 2160 Query: 2078 ADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSS 2137 ADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSS Sbjct: 2161 ADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSS 2220 Query: 2138 L 2138 L Sbjct: 2221 L 2221 >gi|193788548 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 20 [Homo sapiens] Length = 2127 Score = 4232 bits (10975), Expect = 0.0 Identities = 2120/2138 (99%), Positives = 2122/2138 (99%), Gaps = 11/2138 (0%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL D VFT+IFT+EI LKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEEN 1320 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVN NAEEN Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVN-----------NAEEN 1309 Query: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ Sbjct: 1310 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1369 Query: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS Sbjct: 1370 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1429 Query: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI Sbjct: 1430 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1489 Query: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA Sbjct: 1490 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1549 Query: 1561 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA 1620 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA Sbjct: 1550 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA 1609 Query: 1621 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD 1680 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD Sbjct: 1610 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD 1669 Query: 1681 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT 1740 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT Sbjct: 1670 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT 1729 Query: 1741 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP 1800 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP Sbjct: 1730 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP 1789 Query: 1801 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS 1860 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS Sbjct: 1790 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS 1849 Query: 1861 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL 1920 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL Sbjct: 1850 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL 1909 Query: 1921 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS 1980 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS Sbjct: 1910 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS 1969 Query: 1981 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV 2040 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV Sbjct: 1970 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV 2029 Query: 2041 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC 2100 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC Sbjct: 2030 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC 2089 Query: 2101 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2090 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2127 >gi|193794832 calcium channel, voltage-dependent, L type, alpha 1C subunit isoforom 13 [Homo sapiens] Length = 2144 Score = 4232 bits (10975), Expect = 0.0 Identities = 2125/2157 (98%), Positives = 2125/2157 (98%), Gaps = 32/2157 (1%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEEN 1320 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITE NAEEN Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITE-------------NAEEN 1307 Query: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ Sbjct: 1308 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1367 Query: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS Sbjct: 1368 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1427 Query: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI Sbjct: 1428 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1487 Query: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA Sbjct: 1488 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1547 Query: 1561 TLFALVRTALRIKTE-------------------GNLEQANEELRAIIKKIWKRTSMKLL 1601 TLFALVRTALRIKTE GNLEQANEELRAIIKKIWKRTSMKLL Sbjct: 1548 TLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLEQANEELRAIIKKIWKRTSMKLL 1607 Query: 1602 DQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDI 1661 DQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDI Sbjct: 1608 DQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDI 1667 Query: 1662 GPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQT 1721 GPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQT Sbjct: 1668 GPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQT 1727 Query: 1722 FTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRP 1781 FTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRP Sbjct: 1728 FTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRP 1787 Query: 1782 AGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKM 1841 AGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKM Sbjct: 1788 AGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKM 1847 Query: 1842 NHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHL 1901 NHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHL Sbjct: 1848 NHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHL 1907 Query: 1902 ECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGS 1961 ECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGS Sbjct: 1908 ECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGS 1967 Query: 1962 RGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQ 2021 RGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQ Sbjct: 1968 RGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQ 2027 Query: 2022 AGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNI 2081 AGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNI Sbjct: 2028 AGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNI 2087 Query: 2082 LSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 LSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2088 LSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2144 >gi|193788534 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 12 [Homo sapiens] Length = 2146 Score = 4220 bits (10945), Expect = 0.0 Identities = 2120/2157 (98%), Positives = 2122/2157 (98%), Gaps = 30/2157 (1%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL D VFT+IFT+EI LKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEEN 1320 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVN NAEEN Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVN-----------NAEEN 1309 Query: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ Sbjct: 1310 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1369 Query: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS Sbjct: 1370 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1429 Query: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI Sbjct: 1430 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1489 Query: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA Sbjct: 1490 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1549 Query: 1561 TLFALVRTALRIKTE-------------------GNLEQANEELRAIIKKIWKRTSMKLL 1601 TLFALVRTALRIKTE GNLEQANEELRAIIKKIWKRTSMKLL Sbjct: 1550 TLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLEQANEELRAIIKKIWKRTSMKLL 1609 Query: 1602 DQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDI 1661 DQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDI Sbjct: 1610 DQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDI 1669 Query: 1662 GPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQT 1721 GPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQT Sbjct: 1670 GPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQT 1729 Query: 1722 FTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRP 1781 FTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRP Sbjct: 1730 FTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRP 1789 Query: 1782 AGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKM 1841 AGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKM Sbjct: 1790 AGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKM 1849 Query: 1842 NHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHL 1901 NHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHL Sbjct: 1850 NHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHL 1909 Query: 1902 ECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGS 1961 ECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGS Sbjct: 1910 ECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGS 1969 Query: 1962 RGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQ 2021 RGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQ Sbjct: 1970 RGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQ 2029 Query: 2022 AGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNI 2081 AGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNI Sbjct: 2030 AGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNI 2089 Query: 2082 LSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 LSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2090 LSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2146 >gi|193794830 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 10 [Homo sapiens] Length = 2155 Score = 4217 bits (10936), Expect = 0.0 Identities = 2120/2166 (97%), Positives = 2122/2166 (97%), Gaps = 39/2166 (1%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL D VFT+IFT+EI LKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPK----------------------------HYFCDAWNTFDALIVV 1292 LFTVEMILKLIAFKPK HYFCDAWNTFDALIVV Sbjct: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVV 1320 Query: 1293 GSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1352 GSIVDIAITEVN NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT Sbjct: 1321 GSIVDIAITEVN-----------NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1369 Query: 1353 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1412 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC Sbjct: 1370 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1429 Query: 1413 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1472 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV Sbjct: 1430 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1489 Query: 1473 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1532 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK Sbjct: 1490 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1549 Query: 1533 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI 1592 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI Sbjct: 1550 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI 1609 Query: 1593 WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ 1652 WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ Sbjct: 1610 WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ 1669 Query: 1653 AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS 1712 AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS Sbjct: 1670 AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS 1729 Query: 1713 DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN 1772 DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN Sbjct: 1730 DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN 1789 Query: 1773 TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS 1832 TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS Sbjct: 1790 TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS 1849 Query: 1833 QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS 1892 QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS Sbjct: 1850 QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS 1909 Query: 1893 LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF 1952 LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF Sbjct: 1910 LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF 1969 Query: 1953 ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR 2012 ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR Sbjct: 1970 ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR 2029 Query: 2013 PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE 2072 PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE Sbjct: 2030 PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE 2089 Query: 2073 EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR 2132 EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR Sbjct: 2090 EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR 2149 Query: 2133 VYVSSL 2138 VYVSSL Sbjct: 2150 VYVSSL 2155 >gi|192807298 calcium channel, voltage-dependent, L type, alpha 1D subunit isoform c [Homo sapiens] Length = 2137 Score = 2746 bits (7117), Expect = 0.0 Identities = 1453/2156 (67%), Positives = 1659/2156 (76%), Gaps = 136/2156 (6%) Query: 50 LSWQAAIDAARQAKLMGSAGNATISTVSS-TQRKRQQYGKPKKQGSTTATRPPRALLCLT 108 LSWQAAIDAARQAK + + V S +QRKRQQY K KKQG+++ +RP RAL CL+ Sbjct: 51 LSWQAAIDAARQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLS 110 Query: 109 LKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLI 168 L NPIRRACISIVEWKPF+I ILL IFANCVALAIYIPFPEDDSN+TN NLE+VEY FLI Sbjct: 111 LNNPIRRACISIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLI 170 Query: 169 IFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATK-ADGANALGGK 227 IFTVE FLK+IAYGLL HPNAY+RNGWNLLDF+IV+VGLFS ILEQ TK +G N GK Sbjct: 171 IFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGK 230 Query: 228 GAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL 287 GFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL Sbjct: 231 SGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL 290 Query: 288 ELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQ-NGTVCKPGWDGPKHGITNF 346 ELF+GKMHKTC+ + +D+ AE+DP+PCA +G+GRQC NGT C+ GW GP GITNF Sbjct: 291 ELFIGKMHKTCFFAD--SDIVAEEDPAPCAF-SGNGRQCTANGTECRSGWVGPNGGITNF 347 Query: 347 DNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSG 406 DNFAFAMLTVFQCITMEGWTDVLYW+NDA+G + PW+YFV+L+I GSFFVLNLVLGVLSG Sbjct: 348 DNFAFAMLTVFQCITMEGWTDVLYWMNDAMGFELPWVYFVSLVIFGSFFVLNLVLGVLSG 407 Query: 407 EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSM 466 EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENE+EG +E K RN SM Sbjct: 408 EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEEGK-RNTSM 466 Query: 467 PTSETESVNTENVAGGDIEGEN--CGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSN 524 PTSETESVNTENV+G EGEN C L ISKSK SR WRRWNRF RR+CRAAVKS Sbjct: 467 PTSETESVNTENVSG---EGENRGCCGSLCQAISKSKLSRRWRRWNRFNRRRCRAAVKSV 523 Query: 525 VFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYF 584 FYWLVI LVFLNTLTI+SEHYNQP+WLT++QD ANK LLALFT EML+KMYSLGLQAYF Sbjct: 524 TFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYF 583 Query: 585 VSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASL 644 VSLFNRFDCFVVCGGI ETILVE +IMSPLGISV RCVRLLRIFK+TR+W SLSNLVASL Sbjct: 584 VSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLVASL 643 Query: 645 LNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILT 704 LNS++SIASLLLLLFLFIIIFSLLGMQLFGGKFNFDE QT+RSTFDNFPQ+LLTVFQILT Sbjct: 644 LNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQILT 703 Query: 705 GEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTS 764 GEDWN+VMYDGIMAYGGPS GM+VCIYFIILFICGNYILLNVFLAIAVDNLADAESL + Sbjct: 704 GEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNT 763 Query: 765 AQKEEEEEKERKKLARTASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMD 824 AQKEE EEKERKK+AR S E K+ KP V + K+ +D Sbjct: 764 AQKEEAEEKERKKIARKESLENKKN--NKPEVNQIANSD---------------NKVTID 806 Query: 825 DLQPNENEDKSPYPN-----PETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASA 879 D + E+EDK PYP E EE+E+EPE+P GPRPR +SEL++KEK P+PE SA Sbjct: 807 DYR-EEDEDKDPYPPCDVPVGEEEEEEEEDEPEVPAGPRPRRISELNMKEKIAPIPEGSA 865 Query: 880 FFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIV 939 FFI S N R+ CH+++N IFTNLIL FI+LSS +LAAEDP++ SFRN IL YFD Sbjct: 866 FFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYA 925 Query: 940 FTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRV 999 FT IFT+EI LKMT +GAFLHKG+FCRNYFN+LD+LVV VSL+SFGIQSSAI+VVKILRV Sbjct: 926 FTAIFTVEILLKMTTFGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRV 985 Query: 1000 LRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCS 1059 LRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNI+IVTTLLQFMFACIGVQLFKGK Y C+ Sbjct: 986 LRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCT 1045 Query: 1060 DSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPE 1119 D +K EC+G +I YKDG+VD P+++ R W+NS F+FDNVL+AMMALFTVSTFEGWP Sbjct: 1046 DEAKSNPEECRGLFILYKDGDVDSPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPA 1105 Query: 1120 LLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKN 1179 LLY++IDS+ E+ GPIYN+RVEISIFFIIYIII+AFFMMNIFVGFVIVTFQEQGE+EYKN Sbjct: 1106 LLYKAIDSNGENIGPIYNHRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKN 1165 Query: 1180 CELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQ 1239 CELDKNQRQCVEYALKARPLRRYIPKN +QYK WYVVNS+ FEY+MFVLI+LNT+CLAMQ Sbjct: 1166 CELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQ 1225 Query: 1240 HYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIA 1299 HY QS +F AM+ILNM+FTG+FTVEM+LK+IAFKPK YF DAWNTFD+LIV+GSI+D+A Sbjct: 1226 HYEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIIDVA 1285 Query: 1300 ITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQA 1359 ++E + N+EE++RISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQA Sbjct: 1286 LSEAD-----------NSEESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQA 1334 Query: 1360 LPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQ 1419 LPYVALLI MLFFIYAVIGMQ+FGK+A+ D +INRNNNFQTFPQAVLLLFRCATGEAWQ Sbjct: 1335 LPYVALLIAMLFFIYAVIGMQMFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQ 1394 Query: 1420 DIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNF 1479 +IMLAC+PGK C PES+ + E CGS+FA+ YFISFYMLCAFLIINLFVAVIMDNF Sbjct: 1395 EIMLACLPGKLCDPESDYNPGE--EYTCGSNFAIVYFISFYMLCAFLIINLFVAVIMDNF 1452 Query: 1480 DYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVA 1539 DYLTRDWSILGPHHLDEFKRIW+EYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVA Sbjct: 1453 DYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVA 1512 Query: 1540 CKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMK 1599 CKRLV+MNMPLNSDGTVMFNATLFALVRTAL+IKTEGNLEQANEELRA+IKKIWK+TSMK Sbjct: 1513 CKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMK 1572 Query: 1600 LLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGK-PSQRNALSLQAGLRTL 1658 LLDQVVPPAGDDEVTVGKFYATFLIQ+YFRKFKKRKEQGLVGK P++ ++LQAGLRTL Sbjct: 1573 LLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRTL 1632 Query: 1659 HDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAF 1718 HDIGPEIRRAIS DL +E E EDD+F+R G L GNHV++ SD R + Sbjct: 1633 HDIGPEIRRAISCDLQDDE------PEETKREEEDDVFKRNGALLGNHVNHVNSDRRDSL 1686 Query: 1719 PQTFTTQRPLHINKAG-SSQGDTESPSHEKLVDST-FTPSSYSS------TGSNANINNA 1770 QT TT RPLH+ + DTE P +S +++S T +NAN+NNA Sbjct: 1687 QQTNTTHRPLHVQRPSIPPASDTEKPLFPPAGNSVCHNHHNHNSIGKQVPTSTNANLNNA 1746 Query: 1771 NNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEE 1830 N + RP+ + GH S+ H RE Q + + Sbjct: 1747 NMSKAAHGKRPSIGNLEHVSENGH-----------------HSSHKHDREPQRRSSVKRS 1789 Query: 1831 TSQDETYEVKMNHDTE---------ACSEPSLLSTEMLSYQDD----------------- 1864 S DE D E E S+E Y+DD Sbjct: 1790 DSGDEQLPTICREDPEIHGYFRDPHCLGEQEYFSSEE-CYEDDSSPTWSRQNYGYYSRYP 1848 Query: 1865 ------------ENRQLTLPEEDK---RDIRQSPKRGFL-RSASLGRRASFHLECLKRQK 1908 + Q L ++D D R+SP+R L + + RR+SF+ ECL+RQ Sbjct: 1849 GRNIDSERPRGYHHPQGFLEDDDSPVCYDSRRSPRRRLLPPTPASHRRSSFNFECLRRQS 1908 Query: 1909 DR-----GGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRG 1963 + +T LPLHL+ Q +AVAGL + +SP+ R +ATPPATP R Sbjct: 1909 SQEEVPSSPIFPHRTALPLHLMQQQIMAVAGLDSSKAQKYSPSHSTRSWATPPATPPYRD 1968 Query: 1964 WPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAG 2023 W P P +++E E+ +++N S PS+H SW P + R P SL VPS Sbjct: 1969 WTPCYTPLIQVEQSEALDQVNGSLPSLHRSSWYTDEP----DISYRTFTPASLTVPSSFR 2024 Query: 2024 APGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILS 2083 SA SLVEAVLISEGLG++A+DPKF+ T E+ADACD+TI+EMESAA +L+ Sbjct: 2025 NKNSDKQRSADSLVEAVLISEGLGRYARDPKFVSATKHEIADACDLTIDEMESAASTLLN 2084 Query: 2084 GGAPQSPNGALLPFVNCRDAG-QDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 G NG + P + +D QD G D R EE+L D + +++L Sbjct: 2085 GNVRPRANGDVGPLSHRQDYELQDFGPGYSDEEPDPGR---DEEDLADEMICITTL 2137 >gi|192807300 calcium channel, voltage-dependent, L type, alpha 1D subunit isoform b [Homo sapiens] Length = 2161 Score = 2744 bits (7114), Expect = 0.0 Identities = 1453/2157 (67%), Positives = 1664/2157 (77%), Gaps = 114/2157 (5%) Query: 50 LSWQAAIDAARQAKLMGSAGNATISTVSS-TQRKRQQYGKPKKQGSTTATRPPRALLCLT 108 LSWQAAIDAARQAK + + V S +QRKRQQY K KKQG+++ +RP RAL CL+ Sbjct: 51 LSWQAAIDAARQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLS 110 Query: 109 LKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLI 168 L NPIRRACISIVEWKPF+I ILL IFANCVALAIYIPFPEDDSN+TN NLE+VEY FLI Sbjct: 111 LNNPIRRACISIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLI 170 Query: 169 IFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATK-ADGANALGGK 227 IFTVE FLK+IAYGLL HPNAY+RNGWNLLDF+IV+VGLFS ILEQ TK +G N GK Sbjct: 171 IFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGK 230 Query: 228 GAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL 287 GFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL Sbjct: 231 SGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL 290 Query: 288 ELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQ-NGTVCKPGWDGPKHGITNF 346 ELF+GKMHKTC+ + +D+ AE+DP+PCA +G+GRQC NGT C+ GW GP GITNF Sbjct: 291 ELFIGKMHKTCFFAD--SDIVAEEDPAPCAF-SGNGRQCTANGTECRSGWVGPNGGITNF 347 Query: 347 DNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSG 406 DNFAFAMLTVFQCITMEGWTDVLYW+NDA+G + PW+YFV+L+I GSFFVLNLVLGVLSG Sbjct: 348 DNFAFAMLTVFQCITMEGWTDVLYWMNDAMGFELPWVYFVSLVIFGSFFVLNLVLGVLSG 407 Query: 407 EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSM 466 EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENE+EG +E K RN SM Sbjct: 408 EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEEGK-RNTSM 466 Query: 467 PTSETESVNTENVAGGDIEGEN--CGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSN 524 PTSETESVNTENV+G EGEN C L ISKSK SR WRRWNRF RR+CRAAVKS Sbjct: 467 PTSETESVNTENVSG---EGENRGCCGSLCQAISKSKLSRRWRRWNRFNRRRCRAAVKSV 523 Query: 525 VFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYF 584 FYWLVI LVFLNTLTI+SEHYNQP+WLT++QD ANK LLALFT EML+KMYSLGLQAYF Sbjct: 524 TFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYF 583 Query: 585 VSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASL 644 VSLFNRFDCFVVCGGI ETILVE +IMSPLGISV RCVRLLRIFK+TR+W SLSNLVASL Sbjct: 584 VSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLVASL 643 Query: 645 LNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILT 704 LNS++SIASLLLLLFLFIIIFSLLGMQLFGGKFNFDE QT+RSTFDNFPQ+LLTVFQILT Sbjct: 644 LNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQILT 703 Query: 705 GEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTS 764 GEDWN+VMYDGIMAYGGPS GM+VCIYFIILFICGNYILLNVFLAIAVDNLADAESL + Sbjct: 704 GEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNT 763 Query: 765 AQKEEEEEKERKKLARTASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMD 824 AQKEE EEKERKK+AR S E K+ KP V + K+ +D Sbjct: 764 AQKEEAEEKERKKIARKESLENKKN--NKPEVNQIANSD---------------NKVTID 806 Query: 825 DLQPNENEDKSPYPN-----PETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASA 879 D + E+EDK PYP E EE+E+EPE+P GPRPR +SEL++KEK P+PE SA Sbjct: 807 DYR-EEDEDKDPYPPCDVPVGEEEEEEEEDEPEVPAGPRPRRISELNMKEKIAPIPEGSA 865 Query: 880 FFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIV 939 FFI S N R+ CH+++N IFTNLIL FI+LSS +LAAEDP++ SFRN IL YFD Sbjct: 866 FFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYA 925 Query: 940 FTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRV 999 FT IFT+EI LKMT +GAFLHKG+FCRNYFN+LD+LVV VSL+SFGIQSSAI+VVKILRV Sbjct: 926 FTAIFTVEILLKMTTFGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRV 985 Query: 1000 LRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCS 1059 LRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNI+IVTTLLQFMFACIGVQLFKGK Y C+ Sbjct: 986 LRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCT 1045 Query: 1060 DSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPE 1119 D +K EC+G +I YKDG+VD P+++ R W+NS F+FDNVL+AMMALFTVSTFEGWP Sbjct: 1046 DEAKSNPEECRGLFILYKDGDVDSPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPA 1105 Query: 1120 LLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKN 1179 LLY++IDS+ E+ GPIYN+RVEISIFFIIYIII+AFFMMNIFVGFVIVTFQEQGE+EYKN Sbjct: 1106 LLYKAIDSNGENIGPIYNHRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKN 1165 Query: 1180 CELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQ 1239 CELDKNQRQCVEYALKARPLRRYIPKN +QYK WYVVNS+ FEY+MFVLI+LNT+CLAMQ Sbjct: 1166 CELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQ 1225 Query: 1240 HYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIA 1299 HY QS +F AM+ILNM+FTG+FTVEM+LK+IAFKPK YF DAWNTFD+LIV+GSI+D+A Sbjct: 1226 HYEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIIDVA 1285 Query: 1300 ITEVNPAEH----TQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIK 1355 ++E +P E + N+EE++RISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIK Sbjct: 1286 LSEADPTESENVPVPTATPGNSEESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIK 1345 Query: 1356 SFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATG 1415 SFQALPYVALLI MLFFIYAVIGMQ+FGK+A+ D +INRNNNFQTFPQAVLLLFRCATG Sbjct: 1346 SFQALPYVALLIAMLFFIYAVIGMQMFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATG 1405 Query: 1416 EAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVI 1475 EAWQ+IMLAC+PGK C PES+ + E CGS+FA+ YFISFYMLCAFLIINLFVAVI Sbjct: 1406 EAWQEIMLACLPGKLCDPESDYNPGE--EYTCGSNFAIVYFISFYMLCAFLIINLFVAVI 1463 Query: 1476 MDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCP 1535 MDNFDYLTRDWSILGPHHLDEFKRIW+EYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCP Sbjct: 1464 MDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCP 1523 Query: 1536 HRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKR 1595 HRVACKRLV+MNMPLNSDGTVMFNATLFALVRTAL+IKTEGNLEQANEELRA+IKKIWK+ Sbjct: 1524 HRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKK 1583 Query: 1596 TSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGK-PSQRNALSLQAG 1654 TSMKLLDQVVPPAGDDEVTVGKFYATFLIQ+YFRKFKKRKEQGLVGK P++ ++LQAG Sbjct: 1584 TSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAG 1643 Query: 1655 LRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDG 1714 LRTLHDIGPEIRRAIS DL +E E EDD+F+R G L GNHV++ SD Sbjct: 1644 LRTLHDIGPEIRRAISCDLQDDE------PEETKREEEDDVFKRNGALLGNHVNHVNSDR 1697 Query: 1715 RSAFPQTFTTQRPLHINKAG-SSQGDTESPSHEKLVDST-FTPSSYSS------TGSNAN 1766 R + QT TT RPLH+ + DTE P +S +++S T +NAN Sbjct: 1698 RDSLQQTNTTHRPLHVQRPSIPPASDTEKPLFPPAGNSVCHNHHNHNSIGKQVPTSTNAN 1757 Query: 1767 INNANNTALGRLPRPA----GYPSTVSTVEGHGPPLSPAIR--VQEVAWKLSSNRCHSRE 1820 +NNAN + RP+ + S H P R V+ + + R S + Sbjct: 1758 LNNANMSKAAHGKRPSIGNLEHVSENGHHSSHKHDREPQRRSSVKRTRYYETYIRSDSGD 1817 Query: 1821 SQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDD---------------- 1864 Q +E+ + D E S+E Y+DD Sbjct: 1818 EQLPTICREDPEIHGYF-----RDPHCLGEQEYFSSEE-CYEDDSSPTWSRQNYGYYSRY 1871 Query: 1865 -------------ENRQLTLPEEDK---RDIRQSPKRGFL-RSASLGRRASFHLECLKRQ 1907 + Q L ++D D R+SP+R L + + RR+SF+ ECL+RQ Sbjct: 1872 PGRNIDSERPRGYHHPQGFLEDDDSPVCYDSRRSPRRRLLPPTPASHRRSSFNFECLRRQ 1931 Query: 1908 KDR-----GGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSR 1962 + +T LPLHL+ Q +AVAGL + +SP+ R +ATPPATP R Sbjct: 1932 SSQEEVPSSPIFPHRTALPLHLMQQQIMAVAGLDSSKAQKYSPSHSTRSWATPPATPPYR 1991 Query: 1963 GWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQA 2022 W P P +++E E+ +++N S PS+H SW P + R P SL VPS Sbjct: 1992 DWTPCYTPLIQVEQSEALDQVNGSLPSLHRSSWYTDEP----DISYRTFTPASLTVPSSF 2047 Query: 2023 GAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNIL 2082 SA SLVEAVLISEGLG++A+DPKF+ T E+ADACD+TI+EMESAA +L Sbjct: 2048 RNKNSDKQRSADSLVEAVLISEGLGRYARDPKFVSATKHEIADACDLTIDEMESAASTLL 2107 Query: 2083 SGGAPQSPNGALLPFVNCRDAG-QDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 +G NG + P + +D QD G D R EE+L D + +++L Sbjct: 2108 NGNVRPRANGDVGPLSHRQDYELQDFGPGYSDEEPDPGR---DEEDLADEMICITTL 2161 >gi|4502527 calcium channel, voltage-dependent, L type, alpha 1D subunit isoform a [Homo sapiens] Length = 2181 Score = 2744 bits (7114), Expect = 0.0 Identities = 1457/2177 (66%), Positives = 1668/2177 (76%), Gaps = 134/2177 (6%) Query: 50 LSWQAAIDAARQAKLMGSAGNATISTVSS-TQRKRQQYGKPKKQGSTTATRPPRALLCLT 108 LSWQAAIDAARQAK + + V S +QRKRQQY K KKQG+++ +RP RAL CL+ Sbjct: 51 LSWQAAIDAARQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLS 110 Query: 109 LKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLI 168 L NPIRRACISIVEWKPF+I ILL IFANCVALAIYIPFPEDDSN+TN NLE+VEY FLI Sbjct: 111 LNNPIRRACISIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLI 170 Query: 169 IFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATK-ADGANALGGK 227 IFTVE FLK+IAYGLL HPNAY+RNGWNLLDF+IV+VGLFS ILEQ TK +G N GK Sbjct: 171 IFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGK 230 Query: 228 GAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL 287 GFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL Sbjct: 231 SGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL 290 Query: 288 ELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQ-NGTVCKPGWDGPKHGITNF 346 ELF+GKMHKTC+ + +D+ AE+DP+PCA +G+GRQC NGT C+ GW GP GITNF Sbjct: 291 ELFIGKMHKTCFFAD--SDIVAEEDPAPCAF-SGNGRQCTANGTECRSGWVGPNGGITNF 347 Query: 347 DNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSG 406 DNFAFAMLTVFQCITMEGWTDVLYWVNDA+G +WPW+YFV+LII+GSFFVLNLVLGVLSG Sbjct: 348 DNFAFAMLTVFQCITMEGWTDVLYWVNDAIGWEWPWVYFVSLIILGSFFVLNLVLGVLSG 407 Query: 407 EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSM 466 EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENE+EG +E K RN SM Sbjct: 408 EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEEGK-RNTSM 466 Query: 467 PTSETESVNTENVAGGDIEGEN---CGA-------------------RLAHRISKSKFSR 504 PTSETESVNTENV+G EGEN CG+ R ISKSK SR Sbjct: 467 PTSETESVNTENVSG---EGENRGCCGSLWCWWRRRGAAKAGPSGCRRWGQAISKSKLSR 523 Query: 505 YWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALL 564 WRRWNRF RR+CRAAVKS FYWLVI LVFLNTLTI+SEHYNQP+WLT++QD ANK LL Sbjct: 524 RWRRWNRFNRRRCRAAVKSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLL 583 Query: 565 ALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRL 624 ALFT EML+KMYSLGLQAYFVSLFNRFDCFVVCGGI ETILVE +IMSPLGISV RCVRL Sbjct: 584 ALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRL 643 Query: 625 LRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQT 684 LRIFK+TR+W SLSNLVASLLNS++SIASLLLLLFLFIIIFSLLGMQLFGGKFNFDE QT Sbjct: 644 LRIFKVTRHWTSLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQT 703 Query: 685 RRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYIL 744 +RSTFDNFPQ+LLTVFQILTGEDWN+VMYDGIMAYGGPS GM+VCIYFIILFICGNYIL Sbjct: 704 KRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYIL 763 Query: 745 LNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQELVEKPAVGESKEEKI 804 LNVFLAIAVDNLADAESL +AQKEE EEKERKK+AR S E K+ KP V + Sbjct: 764 LNVFLAIAVDNLADAESLNTAQKEEAEEKERKKIARKESLENKKN--NKPEVNQIANSD- 820 Query: 805 ELKSITADGESPPATKINMDDLQPNENEDKSPYPN-----PETTGEEDEEEPEMPVGPRP 859 K+ +DD + E+EDK PYP E EE+E+EPE+P GPRP Sbjct: 821 --------------NKVTIDDYR-EEDEDKDPYPPCDVPVGEEEEEEEEDEPEVPAGPRP 865 Query: 860 RPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAA 919 R +SEL++KEK P+PE SAFFI S N R+ CH+++N IFTNLIL FI+LSS +LAA Sbjct: 866 RRISELNMKEKIAPIPEGSAFFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSSAALAA 925 Query: 920 EDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSV 979 EDP++ SFRN IL YFD FT IFT+EI LKMT +GAFLHKG+FCRNYFN+LD+LVV V Sbjct: 926 EDPIRSHSFRNTILGYFDYAFTAIFTVEILLKMTTFGAFLHKGAFCRNYFNLLDMLVVGV 985 Query: 980 SLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLL 1039 SL+SFGIQSSAI+VVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNI+IVTTLL Sbjct: 986 SLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLL 1045 Query: 1040 QFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFD 1099 QFMFACIGVQLFKGK Y C+D +K EC+G +I YKDG+VD P+++ R W+NS F+FD Sbjct: 1046 QFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLFILYKDGDVDSPVVRERIWQNSDFNFD 1105 Query: 1100 NVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMN 1159 NVL+AMMALFTVSTFEGWP LLY++IDS+ E+ GPIYN+RVEISIFFIIYIII+AFFMMN Sbjct: 1106 NVLSAMMALFTVSTFEGWPALLYKAIDSNGENIGPIYNHRVEISIFFIIYIIIVAFFMMN 1165 Query: 1160 IFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNST 1219 IFVGFVIVTFQEQGE+EYKNCELDKNQRQCVEYALKARPLRRYIPKN +QYK WYVVNS+ Sbjct: 1166 IFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSS 1225 Query: 1220 YFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKHYF 1279 FEY+MFVLI+LNT+CLAMQHY QS +F AM+ILNM+FTG+FTVEM+LK+IAFKPK YF Sbjct: 1226 PFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFKPKGYF 1285 Query: 1280 CDAWNTFDALIVVGSIVDIAITEVNPAEH----TQCSPSMNAEENSRISITFFRLFRVMR 1335 DAWNTFD+LIV+GSI+D+A++E +P E + N+EE++RISITFFRLFRVMR Sbjct: 1286 SDAWNTFDSLIVIGSIIDVALSEADPTESENVPVPTATPGNSEESNRISITFFRLFRVMR 1345 Query: 1336 LVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINR 1395 LVKLLSRGEGIRTLLWTFIKSFQALPYVALLI MLFFIYAVIGMQ+FGK+A+ D +INR Sbjct: 1346 LVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQMFGKVAMRDNNQINR 1405 Query: 1396 NNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFY 1455 NNNFQTFPQAVLLLFRCATGEAWQ+IMLAC+PGK C PES+ + E CGS+FA+ Y Sbjct: 1406 NNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKLCDPESDYNPGE--EYTCGSNFAIVY 1463 Query: 1456 FISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHL 1515 FISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIW+EYDPEAKGRIKHL Sbjct: 1464 FISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHL 1523 Query: 1516 DVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE 1575 DVVTLLRRIQPPLGFGKLCPHRVACKRLV+MNMPLNSDGTVMFNATLFALVRTAL+IKTE Sbjct: 1524 DVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTE 1583 Query: 1576 GNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRK 1635 GNLEQANEELRA+IKKIWK+TSMKLLDQVVPPAGDDEVTVGKFYATFLIQ+YFRKFKKRK Sbjct: 1584 GNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRK 1643 Query: 1636 EQGLVGK-PSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDD 1694 EQGLVGK P++ ++LQAGLRTLHDIGPEIRRAIS DL +E E EDD Sbjct: 1644 EQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAISCDLQDDE------PEETKREEEDD 1697 Query: 1695 IFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAG-SSQGDTESPSHEKLVDST- 1752 +F+R G L GNHV++ SD R + QT TT RPLH+ + DTE P +S Sbjct: 1698 VFKRNGALLGNHVNHVNSDRRDSLQQTNTTHRPLHVQRPSIPPASDTEKPLFPPAGNSVC 1757 Query: 1753 FTPSSYSS------TGSNANINNANNTALGRLPRPA----GYPSTVSTVEGHGPPLSPAI 1802 +++S T +NAN+NNAN + RP+ + S H P Sbjct: 1758 HNHHNHNSIGKQVPTSTNANLNNANMSKAAHGKRPSIGNLEHVSENGHHSSHKHDREPQR 1817 Query: 1803 R--VQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS 1860 R V+ + + R S + Q +E+ + D E S+E Sbjct: 1818 RSSVKRTRYYETYIRSDSGDEQLPTICREDPEIHGYF-----RDPHCLGEQEYFSSEE-C 1871 Query: 1861 YQDD-----------------------------ENRQLTLPEEDK---RDIRQSPKRGFL 1888 Y+DD + Q L ++D D R+SP+R L Sbjct: 1872 YEDDSSPTWSRQNYGYYSRYPGRNIDSERPRGYHHPQGFLEDDDSPVCYDSRRSPRRRLL 1931 Query: 1889 -RSASLGRRASFHLECLKRQKDR-----GGDISQKTVLPLHLVHHQALAVAGLSPLLQRS 1942 + + RR+SF+ ECL+RQ + +T LPLHL+ Q +AVAGL + Sbjct: 1932 PPTPASHRRSSFNFECLRRQSSQEEVPSSPIFPHRTALPLHLMQQQIMAVAGLDSSKAQK 1991 Query: 1943 HSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGG 2002 +SP+ R +ATPPATP R W P P +++E E+ +++N S PS+H SW P Sbjct: 1992 YSPSHSTRSWATPPATPPYRDWTPCYTPLIQVEQSEALDQVNGSLPSLHRSSWYTDEP-- 2049 Query: 2003 GGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQE 2062 + R P SL VPS SA SLVEAVLISEGLG++A+DPKF+ T E Sbjct: 2050 --DISYRTFTPASLTVPSSFRNKNSDKQRSADSLVEAVLISEGLGRYARDPKFVSATKHE 2107 Query: 2063 LADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAG-QDRAGGEEDAGCVRARG 2121 +ADACD+TI+EMESAA +L+G NG + P + +D QD G D R Sbjct: 2108 IADACDLTIDEMESAASTLLNGNVRPRANGDVGPLSHRQDYELQDFGPGYSDEEPDPGR- 2166 Query: 2122 RPSEEELQDSRVYVSSL 2138 EE+L D + +++L Sbjct: 2167 --DEEDLADEMICITTL 2181 >gi|53832007 calcium channel, voltage-dependent, L type, alpha 1F subunit [Homo sapiens] Length = 1977 Score = 2294 bits (5944), Expect = 0.0 Identities = 1265/2148 (58%), Positives = 1496/2148 (69%), Gaps = 235/2148 (10%) Query: 16 QGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATIST 75 +G +P P+ AN AG PE PG A + + G++G Sbjct: 5 EGGKDTTPEPSPAN-----GAGPGPEWGLCPGPP---------AVEGESSGASG------ 44 Query: 76 VSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIF 135 T ++R Q+ K K +A R PRAL CLTL NP+RR+CISIVEWKPF+I+ILLTIF Sbjct: 45 -LGTPKRRNQHSKHKTVAVASAQRSPRALFCLTLANPLRRSCISIVEWKPFDILILLTIF 103 Query: 136 ANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGW 195 ANCVAL +YIPFPEDDSN N NLE+VEY+FL+IFTVE LK++AYGL+ HP+AY+RNGW Sbjct: 104 ANCVALGVYIPFPEDDSNTANHNLEQVEYVFLVIFTVETVLKIVAYGLVLHPSAYIRNGW 163 Query: 196 NLLDFIIVVVGLFSAILEQATKADG-ANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSL 254 NLLDFIIVVVGLFS +LEQ G A GGK GFDVKALRAFRVLRPLRLVSGVPSL Sbjct: 164 NLLDFIIVVVGLFSVLLEQGPGRPGDAPHTGGKPGGFDVKALRAFRVLRPLRLVSGVPSL 223 Query: 255 QVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDPS 314 +VLNSI+KA+VPLLHIALLVLFVIIIYAIIGLELF+G+MHKTCY +D+ AE+DPS Sbjct: 224 HIVLNSIMKALVPLLHIALLVLFVIIIYAIIGLELFLGRMHKTCYFLG--SDMEAEEDPS 281 Query: 315 PCALETGHGRQCQ-NGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVN 373 PCA +G GR C N T C+ W GP GITNFDNF FAMLTVFQC+TMEGWTDVLYW+ Sbjct: 282 PCA-SSGSGRACTLNQTECRGRWPGPNGGITNFDNFFFAMLTVFQCVTMEGWTDVLYWMQ 340 Query: 374 DAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEED 433 DA+G + PW+YFV+L+I GSFFVLNLVLGVLSGEFSKEREKAKARGDFQK REKQQ+EED Sbjct: 341 DAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKQREKQQMEED 400 Query: 434 LKGYLDWITQAEDIDPEN----------EDEGMDEEKPR--------------------- 462 L+GYLDWITQAE++D E+ +EG +P+ Sbjct: 401 LRGYLDWITQAEELDMEDPSADDNLGSMAEEGRAGHRPQLAELTNRRRGRLRWFSHSTRS 460 Query: 463 ------NMSMPTSETESVNTENVAGGDIEG--ENCGARLAHRISKSKFSRYWRRWNRFCR 514 + S+P S+T S+ + EG +C R ++I K++ R RR NR R Sbjct: 461 THSTSSHASLPASDTGSMTETQGDEDEEEGALASC-TRCLNKIMKTRVCRRLRRANRVLR 519 Query: 515 RKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLK 574 +CR AVKSN YW V+ LVFLNTLTIASEH+ QP WLT++Q+ ANK LL LFT EMLLK Sbjct: 520 ARCRRAVKSNACYWAVLLLVFLNTLTIASEHHGQPVWLTQIQEYANKVLLCLFTVEMLLK 579 Query: 575 MYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYW 634 +Y LG AY S FNRFDCFVVCGGILET LVE M PLGISVLRCVRLLRIFK+TR+W Sbjct: 580 LYGLGPSAYVSSFFNRFDCFVVCGGILETTLVEVGAMQPLGISVLRCVRLLRIFKVTRHW 639 Query: 635 NSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQ 694 SLSNLVASLLNS++SIASLLLLLFLFIIIFSLLGMQLFGGKFNFD+ T+RSTFD FPQ Sbjct: 640 ASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDQTHTKRSTFDTFPQ 699 Query: 695 SLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVD 754 +LLTVFQILTGEDWN VMYDGIMAYGGP FPGMLVCIYFIILFICGNYILLNVFLAIAVD Sbjct: 700 ALLTVFQILTGEDWNVVMYDGIMAYGGPFFPGMLVCIYFIILFICGNYILLNVFLAIAVD 759 Query: 755 NLADAESLTSAQKEEEEEKERKKLARTASPEKKQELVEKPAVGESKEEKIELKSITADGE 814 NLA ++ T+ K E+ E+ P++ + LV P V + +EE + Sbjct: 760 NLASGDAGTAKDKGGEKSNEKD------LPQENEGLV--PGVEKEEEEGARREGA----- 806 Query: 815 SPPATKINMDDLQPNENEDKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPM 874 D++ E E+ EE+EEE E L E+ KEK VP+ Sbjct: 807 ----------DMEEEEEEE-----------EEEEEEEEEEGAGGVELLQEVVPKEKVVPI 845 Query: 875 PEASAFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILF 934 PE SAFF S N R CH +++ +FTNLIL FI+LSS+SLAAEDP++ SFRNHIL Sbjct: 846 PEGSAFFCLSQTNPLRKGCHTLIHHHVFTNLILVFIILSSVSLAAEDPIRAHSFRNHILG 905 Query: 935 YFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVV 994 YFD FT+IFT+EI LKMT +GAFLH+GSFCR++FN+LDLLVVSVSLISFGI SSAI+VV Sbjct: 906 YFDYAFTSIFTVEILLKMTVFGAFLHRGSFCRSWFNMLDLLVVSVSLISFGIHSSAISVV 965 Query: 995 KILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGK 1054 KILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNI+IVTTLLQFMFACIGVQLFKGK Sbjct: 966 KILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGK 1025 Query: 1055 LYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTF 1114 YTC+D +K T ECKG+++ Y DG+V P+++ R W NS F+FDNVL+AMMALFTVSTF Sbjct: 1026 FYTCTDEAKHTPQECKGSFLVYPDGDVSRPLVRERLWVNSDFNFDNVLSAMMALFTVSTF 1085 Query: 1115 EGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGE 1174 EGWP LLY++ID++ ED GPIYNYRVEIS+FFI+YIIIIAFFMMNIFVGFVI+TF+ QGE Sbjct: 1086 EGWPALLYKAIDAYAEDHGPIYNYRVEISVFFIVYIIIIAFFMMNIFVGFVIITFRAQGE 1145 Query: 1175 QEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTI 1234 QEY+NCELDKNQRQCVEYALKA+PLRRYIPKN HQY+VW VNS FEYLMF+LILLNT+ Sbjct: 1146 QEYQNCELDKNQRQCVEYALKAQPLRRYIPKNPHQYRVWATVNSAAFEYLMFLLILLNTV 1205 Query: 1235 CLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGS 1294 LAMQHY Q+ F AM+ILNM+FTGLFT+EM+LK+IAFKPKHYF DAWNTFDALIVVGS Sbjct: 1206 ALAMQHYEQTAPFNYAMDILNMVFTGLFTIEMVLKIIAFKPKHYFTDAWNTFDALIVVGS 1265 Query: 1295 IVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFI 1354 IVDIA+TEVN H ++E++SRISITFFRLFRVMRLVKLLS+GEGIRTLLWTFI Sbjct: 1266 IVDIAVTEVNNGGHL----GESSEDSSRISITFFRLFRVMRLVKLLSKGEGIRTLLWTFI 1321 Query: 1355 KSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCAT 1414 KSFQALPYVALLI M+FFIYAVIGMQ+FGK+AL D T+INRNNNFQTFPQAVLLLFRCAT Sbjct: 1322 KSFQALPYVALLIAMIFFIYAVIGMQMFGKVALQDGTQINRNNNFQTFPQAVLLLFRCAT 1381 Query: 1415 GEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAV 1474 GEAWQ+IMLA +PG +C PES+ E CGS+FA+ YFISF+MLCAFLIINLFVAV Sbjct: 1382 GEAWQEIMLASLPGNRCDPESDFGPGE--EFTCGSNFAIAYFISFFMLCAFLIINLFVAV 1439 Query: 1475 IMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLC 1534 IMDNFDYLTRDWSILGPHHLDEFKRIW+EYDP AKGRIKHLDVV LLRRIQPPLGFGKLC Sbjct: 1440 IMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPGAKGRIKHLDVVALLRRIQPPLGFGKLC 1499 Query: 1535 PHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWK 1594 PHRVACKRLV+MNMPLNSDGTV FNATLFALVRT+L+IKTEGNLEQAN+ELR +IKKIWK Sbjct: 1500 PHRVACKRLVAMNMPLNSDGTVTFNATLFALVRTSLKIKTEGNLEQANQELRIVIKKIWK 1559 Query: 1595 RTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALS-LQA 1653 R KLLD+V+PP ++EVTVGKFYATFLIQ+YFRKF++RKE+GL+G + + S LQA Sbjct: 1560 RMKQKLLDEVIPPPDEEEVTVGKFYATFLIQDYFRKFRRRKEKGLLGNDAAPSTSSALQA 1619 Query: 1654 GLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSD 1713 GLR+L D+GPE+R+A++ D EEE +E V E D+ Sbjct: 1620 GLRSLQDLGPEMRQALTCDTEEEEE---EGQEGVEEEDEKDL------------------ 1658 Query: 1714 GRSAFPQTFTTQRPLHINKAGSSQGDTES---PSHEKLVDS-TFTPSS---YSSTGSNAN 1766 T + +++ + +G S P ++L DS +F PS + T S + Sbjct: 1659 ---------ETNKATMVSQPSARRGSGISVSLPVGDRLPDSLSFGPSDDDRGTPTSSQPS 1709 Query: 1767 INNANNTALGRLPRPAGYPSTVSTV--EGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAA 1824 + A + R G + + T+ EG+ P Sbjct: 1710 VPQAGSNTHRR-----GSGALIFTIPEEGNSQP-------------------------KG 1739 Query: 1825 MAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKR--DIRQS 1882 GQ + +DE ++++ E P L P +R D Sbjct: 1740 TKGQNKQDEDEEVPDRLSYLDEQAGTPPC-------------SVLLPPHRAQRYMDGHLV 1786 Query: 1883 PKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRS 1942 P+R L GR+ SF ++CL+RQ G LP+ +H+ R+ Sbjct: 1787 PRRRLLPPTPAGRKPSFTIQCLQRQ----GSCED---LPIPGTYHRG-----------RN 1828 Query: 1943 HSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGG 2002 P +ATPP RG L EG L Sbjct: 1829 SGPNRAQGSWATPP----QRGRLLYAPLLLVEEGAAGEGYL------------------- 1865 Query: 2003 GGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQE 2062 G SS R L VP P GSA SLVEAVLISEGLG FA+DP+F+ + QE Sbjct: 1866 GRSSGPLRTF-TCLHVPGTHSDPSHGKRGSADSLVEAVLISEGLGLFARDPRFVALAKQE 1924 Query: 2063 LADACDMTIEEMESAADNILSGGAPQ--SPNGALLPFVNCRDAGQDRA 2108 +ADAC +T++EM++AA ++L+ G S ++L + D G + A Sbjct: 1925 IADACRLTLDEMDNAASDLLAQGTSSLYSDEESILSRFDEEDLGDEMA 1972 >gi|110349767 calcium channel, voltage-dependent, L type, alpha 1S subunit [Homo sapiens] Length = 1873 Score = 2286 bits (5923), Expect = 0.0 Identities = 1168/1714 (68%), Positives = 1381/1714 (80%), Gaps = 60/1714 (3%) Query: 77 SSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFA 136 SS Q + + +PKK RPPRAL CLTL+NP+R+ACISIVEWKPFE IILLTIFA Sbjct: 4 SSPQDEGLRKKQPKKPVPEILPRPPRALFCLTLENPLRKACISIVEWKPFETIILLTIFA 63 Query: 137 NCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWN 196 NCVALA+Y+P PEDD+N+ N LE++EY FLI+F++EA +K+IAYG LFH +AYLR+GWN Sbjct: 64 NCVALAVYLPMPEDDNNSLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRSGWN 123 Query: 197 LLDFIIVVVGLFSAILEQATKADGANA-LGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQ 255 +LDF IV +G+F+ ILEQ A + KGAG DVKALRAFRVLRPLRLVSGVPSLQ Sbjct: 124 VLDFTIVFLGVFTVILEQVNVIQSHTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVPSLQ 183 Query: 256 VVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCY--NQEGIADVPAEDDP 313 VVLNSI KAM+PL HIALLVLF++IIYAIIGLELF GKMHKTCY + +A V E+ P Sbjct: 184 VVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENEE-P 242 Query: 314 SPCALETGHGRQCQ-NGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWV 372 SPCA TG GR+C NG+ C+ GW GP HGIT+FDNF F+MLTV+QCITMEGWTDVLYWV Sbjct: 243 SPCA-RTGSGRRCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYWV 301 Query: 373 NDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEE 432 NDA+G +WPWIYFVTLI++GSFF+LNLVLGVLSGEF+KEREKAK+RG FQKLREKQQL+E Sbjct: 302 NDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLDE 361 Query: 433 DLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVAGGDIEGENCGAR 492 DL+GY+ WITQ E +D E+ EG ++ S+TES+ +I G N Sbjct: 362 DLRGYMSWITQGEVMDVEDFREGK-----LSLDEGGSDTESLY-------EIAGLN---- 405 Query: 493 LAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPNWL 552 +F R+WR+WNR R KC VKS VFYWLVI +V LNTL+IASEH+NQP WL Sbjct: 406 -----KIIQFIRHWRQWNRIFRWKCHDIVKSKVFYWLVILIVALNTLSIASEHHNQPLWL 460 Query: 553 TEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMS 612 T +QD AN+ LL+LFT EML+KMY LGL+ YF+S+FNRFDCFVVC GILE +LVE+ M+ Sbjct: 461 TRLQDIANRVLLSLFTTEMLMKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMT 520 Query: 613 PLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQL 672 PLGISVLRC+RLLRIFKIT+YW SLSNLVASLLNS+RSIASLLLLLFLFI+IF+LLGMQL Sbjct: 521 PLGISVLRCIRLLRIFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFIVIFALLGMQL 580 Query: 673 FGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIY 732 FGG+++F++ + RRS FDNFPQ+L++VFQ+LTGEDW S+MY+GIMAYGGPS+PGMLVCIY Sbjct: 581 FGGRYDFEDTEVRRSNFDNFPQALISVFQVLTGEDWTSMMYNGIMAYGGPSYPGMLVCIY 640 Query: 733 FIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQELVE 792 FIILF+CGNYILLNVFLAIAVDNLA+AESLTSAQK + EEK+R+K+++ P+K +E E Sbjct: 641 FIILFVCGNYILLNVFLAIAVDNLAEAESLTSAQKAKAEEKKRRKMSK-GLPDKSEE--E 697 Query: 793 KPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNPETTGEEDEEEPE 852 K + + E+K + + I P K+ +D+ + N NE K PYP+ + G+++E+EPE Sbjct: 698 KSTMAKKLEQKPKGEGI------PTTAKLKIDEFESNVNEVKDPYPSADFPGDDEEDEPE 751 Query: 853 MPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILL 912 +P+ PRPRPL+EL LKEKAVP+PEAS+FFIFS N+ R+ CHRIVN T FTN IL FILL Sbjct: 752 IPLSPRPRPLAELQLKEKAVPIPEASSFFIFSPTNKIRVLCHRIVNATWFTNFILLFILL 811 Query: 913 SSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNIL 972 SS +LAAEDP++ S RN IL +FDI FT++FT+EI LKMT YGAFLHKGSFCRNYFN+L Sbjct: 812 SSAALAAEDPIRADSMRNQILKHFDIGFTSVFTVEIVLKMTTYGAFLHKGSFCRNYFNML 871 Query: 973 DLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNI 1032 DLLVV+VSLIS G++SSAI+VVKILRVLRVLRPLRAINRAKGLKHVVQC+FVAI TIGNI Sbjct: 872 DLLVVAVSLISMGLESSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCMFVAISTIGNI 931 Query: 1033 VIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWE 1092 V+VTTLLQFMFACIGVQLFKGK + C+D SK TE EC+G Y YKDG+ ++ R W Sbjct: 932 VLVTTLLQFMFACIGVQLFKGKFFRCTDLSKMTEEECRGYYYVYKDGDPMQIELRHREWV 991 Query: 1093 NSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIII 1152 +S F FDNVL+AMM+LFTVSTFEGWP+LLY++IDS+ ED GPIYN RVE++IFFIIYII+ Sbjct: 992 HSDFHFDNVLSAMMSLFTVSTFEGWPQLLYKAIDSNAEDVGPIYNNRVEMAIFFIIYIIL 1051 Query: 1153 IAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKV 1212 IAFFMMNIFVGFVIVTFQEQGE EYKNCELDKNQRQCV+YALKARPLR YIPKN +QY+V Sbjct: 1052 IAFFMMNIFVGFVIVTFQEQGETEYKNCELDKNQRQCVQYALKARPLRCYIPKNPYQYQV 1111 Query: 1213 WYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIA 1272 WY+V S+YFEYLMF LI+LNTICL MQHY QS +ILN+ FT +FT+EMILKL+A Sbjct: 1112 WYIVTSSYFEYLMFALIMLNTICLGMQHYNQSEQMNHISDILNVAFTIIFTLEMILKLMA 1171 Query: 1273 FKPKHYFCDAWNTFDALIVVGSIVDIAITEVN----PAEHTQC----SPSMNAEENSRIS 1324 FK + YF D WN FD LIV+GSI+D+ ++E++ + C +++ +E++RIS Sbjct: 1172 FKARGYFGDPWNVFDFLIVIGSIIDVILSEIDTFLASSGGLYCLGGGCGNVDPDESARIS 1231 Query: 1325 ITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGK 1384 FFRLFRVMRL+KLLSR EG+RTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ+FGK Sbjct: 1232 SAFFRLFRVMRLIKLLSRAEGVRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGK 1291 Query: 1385 IALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGE 1444 IAL D T+INRNNNFQTFPQAVLLLFRCATGEAWQ+I+LAC GK C PES+ + E Sbjct: 1292 IALVDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEILLACSYGKLCDPESDYAPGE--E 1349 Query: 1445 TPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEY 1504 CG++FA +YFISFYMLCAFL+INLFVAVIMDNFDYLTRDWSILGPHHLDEFK IWAEY Sbjct: 1350 YTCGTNFAYYYFISFYMLCAFLVINLFVAVIMDNFDYLTRDWSILGPHHLDEFKAIWAEY 1409 Query: 1505 DPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFA 1564 DPEAKGRIKHLDVVTLLRRIQPPLGFGK CPHRVACKRLV MNMPLNSDGTV FNATLFA Sbjct: 1410 DPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLVGMNMPLNSDGTVTFNATLFA 1469 Query: 1565 LVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLI 1624 LVRTAL+IKTEGN EQANEELRAIIKKIWKRTSMKLLDQV+PP GDDEVTVGKFYATFLI Sbjct: 1470 LVRTALKIKTEGNFEQANEELRAIIKKIWKRTSMKLLDQVIPPIGDDEVTVGKFYATFLI 1529 Query: 1625 QEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTL-HDIGPEIRRAISGDLTAEEELDKAM 1683 QE+FRKF KR+E+ G +++ + +QAGLRT+ + PEI R +SGDL AEEEL++AM Sbjct: 1530 QEHFRKFMKRQEE-YYGYRPKKDIVQIQAGLRTIEEEAAPEICRTVSGDLAAEEELERAM 1588 Query: 1684 KEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESP 1743 V AA E+ IFRR GGLFG ++ + ++ P QRPL A + ESP Sbjct: 1589 ---VEAAMEEGIFRRTGGLFGQVDNFLER--TNSLPPVMANQRPLQF--AEIEMEEMESP 1641 Query: 1744 SHEKLVDSTFTPSSYSSTGSNANINNAN-NTALG 1776 + F ++ + AN NNAN N A G Sbjct: 1642 ----VFLEDFPQDPRTNPLARANTNNANANVAYG 1671 Score = 49.7 bits (117), Expect = 3e-05 Identities = 44/151 (29%), Positives = 67/151 (44%), Gaps = 24/151 (15%) Query: 1965 PPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGA 2024 PP P R+E ++ +S+ S+H E TP +R R + S+ A Sbjct: 1737 PPAPCQCPRVESSMPEDRKSSTPGSLH-----EETPH------SRSTRENT----SRCSA 1781 Query: 2025 PGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSG 2084 P + + L++ L+ GLG A D FI T Q LADAC M EE+E A +L G Sbjct: 1782 P------ATALLIQKALVRGGLGTLAADANFIMATGQALADACQMEPEEVEIMATELLKG 1835 Query: 2085 GAPQSPNGALLPFVNCRDAGQDRAGGEEDAG 2115 ++P G + + C + G ++ G Sbjct: 1836 --REAPEG-MASSLGCLNLGSSLGSLDQHQG 1863 >gi|187828880 calcium channel, alpha 1A subunit isoform 3 [Homo sapiens] Length = 2261 Score = 776 bits (2003), Expect = 0.0 Identities = 408/869 (46%), Positives = 564/869 (64%), Gaps = 56/869 (6%) Query: 790 LVEKPAVGESKEEKIELKSITADGESPPATK--INMDDLQPNENEDKSPYPNPETTGEED 847 +V P+ ++ K K + PPA +N +Q N+N + P P E +E+ Sbjct: 1146 IVTNPSGTQTNSAKTARKPDHTTVDIPPACPPPLNHTVVQVNKNANPDPLPKKEEEKKEE 1205 Query: 848 EEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDTIFTNLIL 907 EE+ GP+P MP S+ FI S+ N R CH I+N F IL Sbjct: 1206 EEDDRGEDGPKP--------------MPPYSSMFILSTTNPLRRLCHYILNLRYFEMCIL 1251 Query: 908 FFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRN 967 I +SSI+LAAEDPVQ + RN++L YFD VFT +FT E+ +KM G LH+G++ R+ Sbjct: 1252 MVIAMSSIALAAEDPVQPNAPRNNVLRYFDYVFTGVFTFEMVIKMIDLGLVLHQGAYFRD 1311 Query: 968 YFNILDLLVVSVSLISFGIQSSA----INVVKILRVLRVLRPLRAINRAKGLKHVVQCVF 1023 +NILD +VVS +L++F ++ IN +K LRVLRVLRPL+ I R LK V CV Sbjct: 1312 LWNILDFIVVSGALVAFAFTGNSKGKDINTIKSLRVLRVLRPLKTIKRLPKLKAVFDCVV 1371 Query: 1024 VAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDH 1083 +++ + NI+IV L F+FA + VQLFKGK + C+D SK+ E +C+G Y+ Y+ EV Sbjct: 1372 NSLKNVFNILIVYMLFMFIFAVVAVQLFKGKFFHCTDESKEFEKDCRGKYLLYEKNEVK- 1430 Query: 1084 PIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEIS 1143 + R W+ +F +DNVL A++ LFTVST EGWP++L S+D+ E++GP YR+E+S Sbjct: 1431 --ARDREWKKYEFHYDNVLWALLTLFTVSTGEGWPQVLKHSVDATFENQGPSPGYRMEMS 1488 Query: 1144 IFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYI 1203 IF+++Y ++ FF +NIFV +I+TFQEQG++ + L+KN+R C+++A+ A+PL R++ Sbjct: 1489 IFYVVYFVVFPFFFVNIFVALIIITFQEQGDKMMEEYSLEKNERACIDFAISAKPLTRHM 1548 Query: 1204 PKNQH--QYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGL 1261 P+N+ QY++W V S FEY + +I LNTI L M+ YG S ++ A+ + N++FT L Sbjct: 1549 PQNKQSFQYRMWQFVVSPPFEYTIMAMIALNTIVLMMKFYGASVAYENALRVFNIVFTSL 1608 Query: 1262 FTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENS 1321 F++E +LK++AF +YF DAWN FD + V+GSI DI +TE N+ Sbjct: 1609 FSLECVLKVMAFGILNYFRDAWNIFDFVTVLGSITDILVTEFG---------------NN 1653 Query: 1322 RISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQV 1381 I+++F RLFR RL+KLL +G IR LLWTF++SF+ALPYV LLI MLFFIYA+IGMQV Sbjct: 1654 FINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQV 1713 Query: 1382 FGKIALN--------DTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAP 1433 FG I ++ D +I +NNF+TF QA++LLFR ATGEAW +IML+C+ GK C Sbjct: 1714 FGNIGIDVEDEDSDEDEFQITEHNNFRTFFQALMLLFRSATGEAWHNIMLSCLSGKPC-- 1771 Query: 1434 ESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHH 1493 NS CG+ FA FYF+SF LC+FL++NLFVAVIMDNF+YLTRD SILGPHH Sbjct: 1772 ---DKNSGILTRECGNEFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHH 1828 Query: 1494 LDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSD 1553 LDE+ R+WAEYDP A GRI + D+ +LLR I PPLG GK CPHRVACKRL+ M++P+ D Sbjct: 1829 LDEYVRVWAEYDPAACGRIHYKDMYSLLRVISPPLGLGKKCPHRVACKRLLRMDLPVADD 1888 Query: 1554 GTVMFNATLFALVRTALRIKTE---GNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGD 1610 TV FN+TL AL+RTAL IK + +Q + ELR + IW S K LD +V P Sbjct: 1889 NTVHFNSTLMALIRTALDIKIAKGGADKQQMDAELRKEMMAIWPNLSQKTLDLLVTPHKS 1948 Query: 1611 DEVTVGKFYATFLIQEYFRKFKKRKEQGL 1639 ++TVGK YA +I EY+R+ K +K Q + Sbjct: 1949 TDLTVGKIYAAMMIMEYYRQSKAKKLQAM 1977 Score = 671 bits (1730), Expect = 0.0 Identities = 383/827 (46%), Positives = 507/827 (61%), Gaps = 64/827 (7%) Query: 18 SNYGSPRPA-HANMNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTV 76 + +G PA + + AAAG+ GA S Q G G + Sbjct: 2 ARFGDEMPARYGGGGSGAAAGVVVGSGGGRGAGGSRQG-----------GQPGAQRMYKQ 50 Query: 77 SSTQRKRQQ--YGK-PKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLT 133 S QR R Y P +Q T R +L + N +R+ I EW PFE +IL T Sbjct: 51 SMAQRARTMALYNPIPVRQNCLTVNR---SLFLFSEDNVVRKYAKKITEWPPFEYMILAT 107 Query: 134 IFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRN 193 I ANC+ LA+ P+DD + L+ E F+ IF EA +K+IA G FH +YLRN Sbjct: 108 IIANCIVLALEQHLPDDDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFAFHKGSYLRN 167 Query: 194 GWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPS 253 GWN++DF++V+ G+ + + G FD++ LRA RVLRPL+LVSG+PS Sbjct: 168 GWNVMDFVVVLTGILATV----------------GTEFDLRTLRAVRVLRPLKLVSGIPS 211 Query: 254 LQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDP 313 LQVVL SI+KAM+PLL I LL+ F I+I+AIIGLE +MGK H TC+ +EG D+ E P Sbjct: 212 LQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKFHTTCF-EEGTDDIQGES-P 269 Query: 314 SPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVN 373 +PC E R C NGT C+P W+GP +GIT FDN FA+LTVFQCITMEGWTD+LY N Sbjct: 270 APCGTEEP-ARTCPNGTKCQPYWEGPNNGITQFDNILFAVLTVFQCITMEGWTDLLYNSN 328 Query: 374 DAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEED 433 DA G W W+YF+ LIIIGSFF+LNLVLGVLSGEF+KERE+ + R F KLR +QQ+E + Sbjct: 329 DASGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFAKERERVENRRAFLKLRRQQQIERE 388 Query: 434 LKGYLDWITQAEDIDPENEDEGMDEEKP-----RNMSMPTSETESVNTENVAGGDIEGEN 488 L GY++WI++AE++ ++ ++ P R ++ S+T+ +N E + + Sbjct: 389 LNGYMEWISKAEEVILAEDETDGEQRHPFDGALRRTTIKKSKTDLLNPEEAEDQLADIAS 448 Query: 489 CG---ARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEH 545 G AR + + +K + S ++ + R R R VK+ FYW V+ LV LNTL +A H Sbjct: 449 VGSPFARASIKSAKLENSTFFHKKERRMRFYIRRMVKTQAFYWTVLSLVALNTLCVAIVH 508 Query: 546 YNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETIL 605 YNQP WL++ A L LF +EM +KMY LG + YF S FN FDC V+ G I E I Sbjct: 509 YNQPEWLSDFLYYAEFIFLGLFMSEMFIKMYGLGTRPYFHSSFNCFDCGVIIGSIFEVIW 568 Query: 606 VETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIF 665 K + GISVLR +RLLRIFK+T+YW SL NLV SLLNS++SI SLL LLFLFI++F Sbjct: 569 AVIKPGTSFGISVLRALRLLRIFKVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVF 628 Query: 666 SLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFP 725 +LLGMQLFGG+FNFDE T + FD FP +++TVFQILTGEDWN VMYDGI + GG Sbjct: 629 ALLGMQLFGGQFNFDE-GTPPTNFDTFPAAIMTVFQILTGEDWNEVMYDGIKSQGGVQ-G 686 Query: 726 GMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERK--------- 776 GM+ IYFI+L + GNY LLNVFLAIAVDNLA+A+ LT ++EEEE +K Sbjct: 687 GMVFSIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEEEEAANQKLALQKAKEV 746 Query: 777 ------KLARTASPEKKQELVEKPA--VGESKEEKIELKSITADGES 815 A + K+Q+ +KPA V E + ++ +++ A E+ Sbjct: 747 AEVSPLSAANMSIAVKEQQKNQKPAKSVWEQRTSEMRKQNLLASREA 793 Score = 202 bits (513), Expect = 4e-51 Identities = 176/705 (24%), Positives = 317/705 (44%), Gaps = 120/705 (17%) Query: 80 QRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCV 139 + K+++ + + P ++ L+ NP+RR C I+ + FE+ IL+ I + + Sbjct: 1200 EEKKEEEEDDRGEDGPKPMPPYSSMFILSTTNPLRRLCHYILNLRYFEMCILMVIAMSSI 1259 Query: 140 ALAIYIPFPEDDSNATNSNLERV-EYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLL 198 ALA P NA +N+ R +Y+F +FT E +K+I GL+ H AY R+ WN+L Sbjct: 1260 ALAAEDPV---QPNAPRNNVLRYFDYVFTGVFTFEMVIKMIDLGLVLHQGAYFRDLWNIL 1316 Query: 199 DFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVL 258 DFI+V L + +K N +K+LR RVLRPL+ + +P L+ V Sbjct: 1317 DFIVVSGALVAFAFTGNSKGKDINT---------IKSLRVLRVLRPLKTIKRLPKLKAVF 1367 Query: 259 NSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGK-MHKTCYNQEGIADVPAEDDPSPCA 317 + ++ ++ + +I ++ + + I+A++ ++LF GK H T ++E D Sbjct: 1368 DCVVNSLKNVFNILIVYMLFMFIFAVVAVQLFKGKFFHCTDESKEFEKDC---------- 1417 Query: 318 LETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAV- 376 G + V + K+ ++DN +A+LT+F T EGW VL DA Sbjct: 1418 --RGKYLLYEKNEVKARDREWKKYEF-HYDNVLWALLTLFTVSTGEGWPQVLKHSVDATF 1474 Query: 377 --------GRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQ 428 R I++V ++ FF +N+ + ++ F ++ GD K+ E+ Sbjct: 1475 ENQGPSPGYRMEMSIFYVVYFVVFPFFFVNIFVALIIITFQEQ-------GD--KMMEEY 1525 Query: 429 QLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVAGGDIEGEN 488 LE++ + +D+ A KP MP Sbjct: 1526 SLEKNERACIDFAISA---------------KPLTRHMP--------------------- 1549 Query: 489 CGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQ 548 ++K S +R W V S F + ++ ++ LNT+ + + Y Sbjct: 1550 ----------QNKQSFQYRMWQ---------FVVSPPFEYTIMAMIALNTIVLMMKFYGA 1590 Query: 549 PNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVET 608 N +LF+ E +LK+ + G+ YF +N FD V G I + ILV Sbjct: 1591 SVAYENALRVFNIVFTSLFSLECVLKVMAFGILNYFRDAWNIFDFVTVLGSITD-ILVTE 1649 Query: 609 KIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLL 668 + + +S LR R R+ K+ R ++ L+ + + S +++ + LL+ + I++++ Sbjct: 1650 FGNNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAII 1709 Query: 669 GMQLFGG--------KFNFDEMQ-TRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAY 719 GMQ+FG + DE Q T + F F Q+L+ +F+ TGE W+++M + Sbjct: 1710 GMQVFGNIGIDVEDEDSDEDEFQITEHNNFRTFFQALMLLFRSATGEAWHNIMLSCLSGK 1769 Query: 720 GGPSFPGML--------VCIYFI-ILFICGNYILLNVFLAIAVDN 755 G+L YF+ +F+C ++++LN+F+A+ +DN Sbjct: 1770 PCDKNSGILTRECGNEFAYFYFVSFIFLC-SFLMLNLFVAVIMDN 1813 Score = 144 bits (362), Expect = 1e-33 Identities = 179/785 (22%), Positives = 325/785 (41%), Gaps = 161/785 (20%) Query: 480 AGGDIEGENCGARLAHRISKSKFSRYWRRWNRF-CRRKCRAAVKS-------NV------ 525 AGG +G GA+ ++ S ++ +R +N R+ C +S NV Sbjct: 33 AGGSRQGGQPGAQRMYKQSMAQRARTMALYNPIPVRQNCLTVNRSLFLFSEDNVVRKYAK 92 Query: 526 -------FYWLVIFLVFLNTLTIASEHY---NQPNWLTEVQDTANKALLALFTAEMLLKM 575 F ++++ + N + +A E + + ++E D + +F E +K+ Sbjct: 93 KITEWPPFEYMILATIIANCIVLALEQHLPDDDKTPMSERLDDTEPYFIGIFCFEAGIKI 152 Query: 576 YSLGLQ----AYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKIT 631 +LG +Y + +N D VV GIL T+ E + LR VR+LR K+ Sbjct: 153 IALGFAFHKGSYLRNGWNVMDFVVVLTGILATVGTE------FDLRTLRAVRVLRPLKLV 206 Query: 632 RYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNF-------DEMQT 684 SL ++ S++ ++ + + LLLF I+IF+++G++ + GKF+ D++Q Sbjct: 207 SGIPSLQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKFHTTCFEEGTDDIQG 266 Query: 685 RR------------------------------STFDNFPQSLLTVFQILTGEDWNSVMYD 714 + FDN ++LTVFQ +T E W ++Y+ Sbjct: 267 ESPAPCGTEEPARTCPNGTKCQPYWEGPNNGITQFDNILFAVLTVFQCITMEGWTDLLYN 326 Query: 715 GIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKE 774 A G +YFI L I G++ +LN+ L + A +E+E Sbjct: 327 SNDASGNT-----WNWLYFIPLIIIGSFFMLNLVLGVLSGEFA-------------KERE 368 Query: 775 RKKLARTASPEKKQELVEKPAVGE----SKEEKIELKSITADGES--PPATKINMDDLQP 828 R + R ++Q+ +E+ G SK E++ L DGE P + ++ Sbjct: 369 RVENRRAFLKLRRQQQIERELNGYMEWISKAEEVILAEDETDGEQRHPFDGALRRTTIK- 427 Query: 829 NENEDKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNR 888 + K+ NPE ED+ VG P + +K + E S FF R Sbjct: 428 ---KSKTDLLNPEEA--EDQLADIASVGS---PFARASIKSAKL---ENSTFF-HKKERR 475 Query: 889 FRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEI 948 R R+V F +L + L+++ +A Q + + L+Y + +F +F E+ Sbjct: 476 MRFYIRRMVKTQAFYWTVLSLVALNTLCVAIVHYNQ-PEWLSDFLYYAEFIFLGLFMSEM 534 Query: 949 ALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISF---GIQSSAINVVKILRVLRVLRP 1005 +KM G + + FN D V+ S+ I+ + +LR LR+LR Sbjct: 535 FIKMYGLGT----RPYFHSSFNCFDCGVIIGSIFEVIWAVIKPGTSFGISVLRALRLLRI 590 Query: 1006 LRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQT 1065 + L+++V + ++++I +++ + L +FA +G+QLF G+ + + + T Sbjct: 591 FKVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQ-FNFDEGTPPT 649 Query: 1066 EAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSI 1125 +FD AA+M +F + T E W E++Y I Sbjct: 650 -------------------------------NFDTFPAAIMTVFQILTGEDWNEVMYDGI 678 Query: 1126 DSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVI--------VTFQEQGEQEY 1177 S +G + SI+FI+ + + ++N+F+ + +T EQ E+E Sbjct: 679 KSQGGVQGGMV-----FSIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEEEEA 733 Query: 1178 KNCEL 1182 N +L Sbjct: 734 ANQKL 738 Score = 114 bits (285), Expect = 1e-24 Identities = 96/331 (29%), Positives = 162/331 (48%), Gaps = 33/331 (9%) Query: 879 AFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAED--PVQHTSFRNHILFYF 936 + F+FS +N R +I F +IL I+ + I LA E P + + L Sbjct: 77 SLFLFSEDNVVRKYAKKITEWPPFEYMILATIIANCIVLALEQHLPDDDKTPMSERLDDT 136 Query: 937 DIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLI-SFGIQSSAINVVK 995 + F IF E +K+ A G HKGS+ RN +N++D +VV ++ + G + ++ Sbjct: 137 EPYFIGIFCFEAGIKIIALGFAFHKGSYLRNGWNVMDFVVVLTGILATVGTEFD----LR 192 Query: 996 ILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKL 1055 LR +RVLRPL+ ++ L+ V++ + A+ + I ++ +FA IG++ + GK Sbjct: 193 TLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKF 252 Query: 1056 YT------CSDSSKQTEAEC--KGNYITYKDGEVDHPIIQPRSWE---NSKFDFDNVLAA 1104 +T D ++ A C + T +G P WE N FDN+L A Sbjct: 253 HTTCFEEGTDDIQGESPAPCGTEEPARTCPNGTKCQPY-----WEGPNNGITQFDNILFA 307 Query: 1105 MMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGF 1164 ++ +F T EGW +LLY S D+ G +N+ ++FI III +FFM+N+ +G Sbjct: 308 VLTVFQCITMEGWTDLLYNSNDA----SGNTWNW-----LYFIPLIIIGSFFMLNLVLGV 358 Query: 1165 VIVTFQEQGEQ-EYKNCELDKNQRQCVEYAL 1194 + F ++ E+ E + L ++Q +E L Sbjct: 359 LSGEFAKERERVENRRAFLKLRRQQQIEREL 389 Score = 113 bits (282), Expect = 2e-24 Identities = 74/294 (25%), Positives = 138/294 (46%), Gaps = 42/294 (14%) Query: 1195 KARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNIL 1254 K R +R YI + +V + F + + L+ LNT+C+A+ HY Q + Sbjct: 472 KERRMRFYIRR---------MVKTQAFYWTVLSLVALNTLCVAIVHYNQPEWLSDFLYYA 522 Query: 1255 NMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPS 1314 +F GLF EM +K+ + YF ++N FD +++GSI ++ + P Sbjct: 523 EFIFLGLFMSEMFIKMYGLGTRPYFHSSFNCFDCGVIIGSIFEVIWAVIKP--------- 573 Query: 1315 MNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIY 1374 + I+ R R++R+ K+ +R L+ + + S +++ + L+ + ++ Sbjct: 574 -----GTSFGISVLRALRLLRIFKVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVF 628 Query: 1375 AVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPE 1434 A++GMQ+FG + E NF TFP A++ +F+ TGE W ++M Sbjct: 629 ALLGMQLFG--GQFNFDEGTPPTNFDTFPAAIMTVFQILTGEDWNEVMY----------- 675 Query: 1435 SEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNF---DYLTRD 1485 ++G G F++ YFI + + ++N+F+A+ +DN LT+D Sbjct: 676 --DGIKSQGGVQGGMVFSI-YFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKD 726 Score = 82.0 bits (201), Expect = 6e-15 Identities = 73/297 (24%), Positives = 130/297 (43%), Gaps = 62/297 (20%) Query: 125 PFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLL 184 PFE I+ I N + L + S A + L +F +F++E LKV+A+G+L Sbjct: 1567 PFEYTIMAMIALNTIVLMMKF---YGASVAYENALRVFNIVFTSLFSLECVLKVMAFGIL 1623 Query: 185 FHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRP 244 Y R+ WN+ DF+ V+ + ++ + G N + ++ LR FR R Sbjct: 1624 ----NYFRDAWNIFDFVTVLGSITDILVTEF----GNNFI-------NLSFLRLFRAARL 1668 Query: 245 LRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGI 304 ++L+ +++++L + +++ L ++ LL+ + IYAIIG+++F GI Sbjct: 1669 IKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVF---------GNIGI 1719 Query: 305 ADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEG 364 DV ED T H NF F A++ +F+ T E Sbjct: 1720 -DVEDEDSDEDEFQITEH---------------------NNFRTFFQALMLLFRSATGEA 1757 Query: 365 WTDVLY-------------WVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEF 408 W +++ + G ++ + YFV+ I + SF +LNL + V+ F Sbjct: 1758 WHNIMLSCLSGKPCDKNSGILTRECGNEFAYFYFVSFIFLCSFLMLNLFVAVIMDNF 1814 Score = 62.0 bits (149), Expect = 6e-09 Identities = 69/302 (22%), Positives = 118/302 (39%), Gaps = 81/302 (26%) Query: 1221 FEYLMFVLILLNTICLAMQHY---GQSCLFKIAMNILNMLFTGLFTVEMILKLIA----F 1273 FEY++ I+ N I LA++ + ++ F G+F E +K+IA F Sbjct: 100 FEYMILATIIANCIVLALEQHLPDDDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFAF 159 Query: 1274 KPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRV 1333 Y + WN D ++V+ I+ TE + + R RV Sbjct: 160 HKGSYLRNGWNVMDFVVVLTGILATVGTEFD--------------------LRTLRAVRV 199 Query: 1334 MRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVF-GKI------- 1385 +R +KL+S ++ +L + +K+ L + LL+ I+A+IG++ + GK Sbjct: 200 LRPLKLVSGIPSLQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKFHTTCFEE 259 Query: 1386 ----------ALNDTTEINR---------------NNNFQTFPQ---AVLLLFRCATGEA 1417 A T E R NN F AVL +F+C T E Sbjct: 260 GTDDIQGESPAPCGTEEPARTCPNGTKCQPYWEGPNNGITQFDNILFAVLTVFQCITMEG 319 Query: 1418 WQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMD 1477 W D++ NS + G+++ YFI ++ +F ++NL + V+ Sbjct: 320 WTDLLY---------------NSNDAS---GNTWNWLYFIPLIIIGSFFMLNLVLGVLSG 361 Query: 1478 NF 1479 F Sbjct: 362 EF 363 >gi|4502523 calcium channel, voltage-dependent, N type, alpha 1B subunit [Homo sapiens] Length = 2339 Score = 768 bits (1982), Expect = 0.0 Identities = 430/947 (45%), Positives = 589/947 (62%), Gaps = 74/947 (7%) Query: 764 SAQKEEEEEKERKKLARTASPEKKQELVEKPAVGESKEEKIELKSITADGESP----PAT 819 + +KE E++ +K A +K++EL + +E +L++ P P+T Sbjct: 991 AVEKETTEKEATEKEAEIVEADKEKELRNH----QPREPHCDLETSGTVTVGPMHTLPST 1046 Query: 820 KINMDDLQPNENEDK-------SPYPNPETTGEEDEEEPEMPVGPRPR----PLSELHLK 868 + + QP + +++ S P+P T P M GP P + L+ Sbjct: 1047 CLQKVEEQPEDADNQRNVTRMGSQPPDPNTI----VHIPVMLTGPLGEATVVPSGNVDLE 1102 Query: 869 EKAV----------------PMPEASAFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILL 912 +A P+ S+ F S N R CH IV F +IL I L Sbjct: 1103 SQAEGKKEVEADDVMRSGPRPIVPYSSMFCLSPTNLLRRFCHYIVTMRYFEVVILVVIAL 1162 Query: 913 SSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNIL 972 SSI+LAAEDPV+ S RN+ L Y D +FT +FT E+ +KM G LH G++ R+ +NIL Sbjct: 1163 SSIALAAEDPVRTDSPRNNALKYLDYIFTGVFTFEMVIKMIDLGLLLHPGAYFRDLWNIL 1222 Query: 973 DLLVVSVSLISFGIQSSA---INVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTI 1029 D +VVS +L++F S IN +K LRVLRVLRPL+ I R LK V CV +++ + Sbjct: 1223 DFIVVSGALVAFAFSGSKGKDINTIKSLRVLRVLRPLKTIKRLPKLKAVFDCVVNSLKNV 1282 Query: 1030 GNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPR 1089 NI+IV L F+FA I VQLFKGK + C+D SK+ E +C+G Y+ Y+ EV+ QPR Sbjct: 1283 LNILIVYMLFMFIFAVIAVQLFKGKFFYCTDESKELERDCRGQYLDYEKEEVE---AQPR 1339 Query: 1090 SWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIY 1149 W+ F +DNVL A++ LFTVST EGWP +L S+D+ E++GP YR+E+SIF+++Y Sbjct: 1340 QWKKYDFHYDNVLWALLTLFTVSTGEGWPMVLKHSVDATYEEQGPSPGYRMELSIFYVVY 1399 Query: 1150 IIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQH- 1208 ++ FF +NIFV +I+TFQEQG++ C L+KN+R C+++A+ A+PL RY+P+N+ Sbjct: 1400 FVVFPFFFVNIFVALIIITFQEQGDKVMSECSLEKNERACIDFAISAKPLTRYMPQNRQS 1459 Query: 1209 -QYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMI 1267 QYK W V S FEY + +I LNT+ L M+ Y +++ + LN++FT +F++E + Sbjct: 1460 FQYKTWTFVVSPPFEYFIMAMIALNTVVLMMKFYDAPYEYELMLKCLNIVFTSMFSMECV 1519 Query: 1268 LKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITF 1327 LK+IAF +YF DAWN FD + V+GSI DI +TE+ AE N+ I+++F Sbjct: 1520 LKIIAFGVLNYFRDAWNVFDFVTVLGSITDILVTEI-------------AETNNFINLSF 1566 Query: 1328 FRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIAL 1387 RLFR RL+KLL +G IR LLWTF++SF+ALPYV LLI MLFFIYA+IGMQVFG IAL Sbjct: 1567 LRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIAL 1626 Query: 1388 NDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPC 1447 +D T INR+NNF+TF QA++LLFR ATGEAW +IML+C+ + C E +N+TE C Sbjct: 1627 DDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQAC---DEQANATE----C 1679 Query: 1448 GSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPE 1507 GS FA FYF+SF LC+FL++NLFVAVIMDNF+YLTRD SILGPHHLDEF R+WAEYDP Sbjct: 1680 GSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPA 1739 Query: 1508 AKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPL-NSDGTVMFNATLFALV 1566 A GRI + D+ +L+ + PPLG GK CP RVA KRLV MNMP+ N D TV F +TL AL+ Sbjct: 1740 ACGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTLMALI 1799 Query: 1567 RTALRIK---TEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFL 1623 RTAL IK Q + ELR I +W K LD +VPP DE+TVGK YA + Sbjct: 1800 RTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVYAALM 1859 Query: 1624 IQEYFRKFKKRKE--QGLVGKPSQRNALSLQAGLR-TLHDIGPEIRR 1667 I +++++ K ++ Q G SQ +SL L+ TL P + R Sbjct: 1860 IFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLR 1906 Score = 648 bits (1671), Expect = 0.0 Identities = 371/803 (46%), Positives = 486/803 (60%), Gaps = 59/803 (7%) Query: 89 PKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFP 148 P KQ T R +L + N +R+ I EW PFE +IL TI ANC+ LA+ P Sbjct: 63 PVKQNCFTVNR---SLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLP 119 Query: 149 EDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLF 208 + D + L+ E F+ IF EA +K+IA G +FH +YLRNGWN++DF++V+ G+ Sbjct: 120 DGDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGI- 178 Query: 209 SAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPL 268 L G FD++ LRA RVLRPL+LVSG+PSLQVVL SI+KAMVPL Sbjct: 179 ---------------LATAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPL 223 Query: 269 LHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQN 328 L I LL+ F I+++AIIGLE +MGK HK C+ A+ P D PC E R C+ Sbjct: 224 LQIGLLLFFAILMFAIIGLEFYMGKFHKACFPNSTDAE-PVGD--FPCGKEAP-ARLCEG 279 Query: 329 GTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTL 388 T C+ W GP GITNFDN FA+LTVFQCITMEGWTD+LY NDA G W W+YF+ L Sbjct: 280 DTECREYWPGPNFGITNFDNILFAILTVFQCITMEGWTDILYNTNDAAGNTWNWLYFIPL 339 Query: 389 IIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDID 448 IIIGSFF+LNLVLGVLSGEF+KERE+ + R F KLR +QQ+E +L GYL+WI +AE++ Sbjct: 340 IIIGSFFMLNLVLGVLSGEFAKERERVENRRAFLKLRRQQQIERELNGYLEWIFKAEEVM 399 Query: 449 PENEDEGMDEEKP----RNMSMPTSETESVNTENVAGGDIEGENCG-----ARLAHRISK 499 ED +E+ P + + S + ++ E G D + C AR + + K Sbjct: 400 LAEEDRNAEEKSPLDVLKRAATKKSRNDLIHAEE--GEDRFADLCAVGSPFARASLKSGK 457 Query: 500 SKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTA 559 ++ S Y+RR + R R VK+ FYW+V+ +V LNTL +A HYNQP LT A Sbjct: 458 TESSSYFRRKEKMFRFFIRRMVKAQSFYWVVLCVVALNTLCVAMVHYNQPRRLTTTLYFA 517 Query: 560 NKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVL 619 L LF EM LKMY LG ++YF S FN FD V+ G + E + K S GISVL Sbjct: 518 EFVFLGLFLTEMSLKMYGLGPRSYFRSSFNCFDFGVIVGSVFEVVWAAIKPGSSFGISVL 577 Query: 620 RCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNF 679 R +RLLRIFK+T+YW+SL NLV SLLNS++SI SLL LLFLFI++F+LLGMQLFGG+FNF Sbjct: 578 RALRLLRIFKVTKYWSSLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNF 637 Query: 680 DEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFIC 739 + +T + FD FP ++LTVFQILTGEDWN+VMY GI + GG S GM YFI+L + Sbjct: 638 QD-ETPTTNFDTFPAAILTVFQILTGEDWNAVMYHGIESQGGVS-KGMFSSFYFIVLTLF 695 Query: 740 GNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPE-------------- 785 GNY LLNVFLAIAVDNLA+A+ LT +EE EE +KLA + E Sbjct: 696 GNYTLLNVFLAIAVDNLANAQELTK-DEEEMEEAANQKLALQKAKEVAEVSPMSAANISI 754 Query: 786 --KKQELVEKPAVGESKEEKIELKSITAD-----GESPPATKINMDDLQPNENEDKSPYP 838 ++Q + +V E + ++ L+++ A E P ++ + + K+ Sbjct: 755 AARQQNSAKARSVWEQRASQLRLQNLRASCEALYSEMDPEERLRFATTRHLRPDMKTHLD 814 Query: 839 NPETTGEEDEEEPEMPVGPRPRP 861 P E + PVG + RP Sbjct: 815 RPLVV-ELGRDGARGPVGGKARP 836 Score = 216 bits (550), Expect = 2e-55 Identities = 179/716 (25%), Positives = 322/716 (44%), Gaps = 113/716 (15%) Query: 64 LMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPR------ALLCLTLKNPIRRAC 117 L G G AT+ + + Q GK + + PR ++ CL+ N +RR C Sbjct: 1084 LTGPLGEATVVPSGNVDLESQAEGKKEVEADDVMRSGPRPIVPYSSMFCLSPTNLLRRFC 1143 Query: 118 ISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLK 177 IV + FE++IL+ I + +ALA P D N+ L+ ++Y+F +FT E +K Sbjct: 1144 HYIVTMRYFEVVILVVIALSSIALAAEDPVRTDSPR--NNALKYLDYIFTGVFTFEMVIK 1201 Query: 178 VIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALR 237 +I GLL HP AY R+ WN+LDF IVV G A +K N +K+LR Sbjct: 1202 MIDLGLLLHPGAYFRDLWNILDF-IVVSGALVAFAFSGSKGKDINT---------IKSLR 1251 Query: 238 AFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKT 297 RVLRPL+ + +P L+ V + ++ ++ +L+I ++ + + I+A+I ++LF GK Sbjct: 1252 VLRVLRPLKTIKRLPKLKAVFDCVVNSLKNVLNILIVYMLFMFIFAVIAVQLFKGKFF-Y 1310 Query: 298 CYNQEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVF 357 C ++ + E + Q W K ++DN +A+LT+F Sbjct: 1311 CTDESKELERDCRGQYLDYEKEEVEAQPRQ--------W---KKYDFHYDNVLWALLTLF 1359 Query: 358 QCITMEGWTDVLYWVNDAVGRDWP---------WIYFVTLIIIGSFFVLNLVLGVLSGEF 408 T EGW VL DA + I++V ++ FF +N+ + ++ F Sbjct: 1360 TVSTGEGWPMVLKHSVDATYEEQGPSPGYRMELSIFYVVYFVVFPFFFVNIFVALIIITF 1419 Query: 409 SKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPT 468 ++ GD K+ + LE++ + +D+ A KP MP Sbjct: 1420 QEQ-------GD--KVMSECSLEKNERACIDFAISA---------------KPLTRYMP- 1454 Query: 469 SETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYW 528 +++ S ++ W V S F + Sbjct: 1455 ------------------------------QNRQSFQYKTW---------TFVVSPPFEY 1475 Query: 529 LVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLF 588 ++ ++ LNT+ + + Y+ P + N ++F+ E +LK+ + G+ YF + Sbjct: 1476 FIMAMIALNTVVLMMKFYDAPYEYELMLKCLNIVFTSMFSMECVLKIIAFGVLNYFRDAW 1535 Query: 589 NRFDCFVVCGGILETILVE-TKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNS 647 N FD V G I + ++ E + + + +S LR R R+ K+ R ++ L+ + + S Sbjct: 1536 NVFDFVTVLGSITDILVTEIAETNNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQS 1595 Query: 648 VRSIASLLLLLFLFIIIFSLLGMQLFGG-KFNFDEMQTRRSTFDNFPQSLLTVFQILTGE 706 +++ + LL+ + I++++GMQ+FG + D R + F F Q+L+ +F+ TGE Sbjct: 1596 FKALPYVCLLIAMLFFIYAIIGMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGE 1655 Query: 707 DWNSVMYDGIMAYGGPSFPGMLVC------IYFI-ILFICGNYILLNVFLAIAVDN 755 W+ +M + C YF+ +F+C ++++LN+F+A+ +DN Sbjct: 1656 AWHEIMLSCLSNQACDEQANATECGSDFAYFYFVSFIFLC-SFLMLNLFVAVIMDN 1710 Score = 127 bits (319), Expect = 1e-28 Identities = 160/728 (21%), Positives = 303/728 (41%), Gaps = 146/728 (20%) Query: 526 FYWLVIFLVFLNTLTIASEHY---NQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQ- 581 F ++++ + N + +A E + ++E D + +F E +K+ +LG Sbjct: 97 FEYMILATIIANCIVLALEQHLPDGDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVF 156 Query: 582 ---AYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLS 638 +Y + +N D VV GIL T + + LR VR+LR K+ SL Sbjct: 157 HKGSYLRNGWNVMDFVVVLTGILATAGTD------FDLRTLRAVRVLRPLKLVSGIPSLQ 210 Query: 639 NLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNF------------------- 679 ++ S++ ++ + + LLLF I++F+++G++ + GKF+ Sbjct: 211 VVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYMGKFHKACFPNSTDAEPVGDFPCGK 270 Query: 680 --------DEMQTRR---------STFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGP 722 + + R + FDN ++LTVFQ +T E W ++Y+ A G Sbjct: 271 EAPARLCEGDTECREYWPGPNFGITNFDNILFAILTVFQCITMEGWTDILYNTNDAAGNT 330 Query: 723 SFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTA 782 +YFI L I G++ +LN+ L + A +E+ER + R Sbjct: 331 -----WNWLYFIPLIIIGSFFMLNLVLGVLSGEFA-------------KERERVENRRAF 372 Query: 783 SPEKKQELVEKPAVG------ESKEEKIELKSITADGESP------PATKINMDDLQPNE 830 ++Q+ +E+ G +++E + + A+ +SP ATK + +DL E Sbjct: 373 LKLRRQQQIERELNGYLEWIFKAEEVMLAEEDRNAEEKSPLDVLKRAATKKSRNDLIHAE 432 Query: 831 NEDKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFR 890 ED VG P + LK E+S++F FR Sbjct: 433 EG-------------EDRFADLCAVGS---PFARASLKSGKT---ESSSYFR-RKEKMFR 472 Query: 891 LQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIAL 950 R+V F ++L + L+++ +A Q L++ + VF +F E++L Sbjct: 473 FFIRRMVKAQSFYWVVLCVVALNTLCVAMVHYNQPRRLTT-TLYFAEFVFLGLFLTEMSL 531 Query: 951 KMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISF---GIQSSAINVVKILRVLRVLRPLR 1007 KM YG L S+ R+ FN D V+ S+ I+ + + +LR LR+LR + Sbjct: 532 KM--YG--LGPRSYFRSSFNCFDFGVIVGSVFEVVWAAIKPGSSFGISVLRALRLLRIFK 587 Query: 1008 AINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEA 1067 L+++V + ++++I +++ + L +FA +G+QLF G+ Sbjct: 588 VTKYWSSLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQF------------ 635 Query: 1068 ECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDS 1127 ++D E +FD AA++ +F + T E W ++Y I+S Sbjct: 636 -------NFQD-------------ETPTTNFDTFPAAILTVFQILTGEDWNAVMYHGIES 675 Query: 1128 HTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGE--QEYKNCELDKN 1185 +++ S +FI+ + + ++N+F+ + E ++ + E N Sbjct: 676 QGGVSKGMFS-----SFYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEEEMEEAAN 730 Query: 1186 QRQCVEYA 1193 Q+ ++ A Sbjct: 731 QKLALQKA 738 Score = 123 bits (309), Expect = 2e-27 Identities = 76/275 (27%), Positives = 134/275 (48%), Gaps = 35/275 (12%) Query: 1215 VVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFK 1274 +V + F +++ ++ LNT+C+AM HY Q + +F GLF EM LK+ Sbjct: 478 MVKAQSFYWVVLCVVALNTLCVAMVHYNQPRRLTTTLYFAEFVFLGLFLTEMSLKMYGLG 537 Query: 1275 PKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVM 1334 P+ YF ++N FD ++VGS+ ++ + P S I+ R R++ Sbjct: 538 PRSYFRSSFNCFDFGVIVGSVFEVVWAAIKP--------------GSSFGISVLRALRLL 583 Query: 1335 RLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVF-GKIALNDTTEI 1393 R+ K+ +R L+ + + S +++ + L+ + ++A++GMQ+F G+ D T Sbjct: 584 RIFKVTKYWSSLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFQDETP- 642 Query: 1394 NRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAV 1453 NF TFP A+L +F+ TGE W +M + ES+ S F+ Sbjct: 643 --TTNFDTFPAAILTVFQILTGEDWNAVMYHGI-------ESQGGVSK-------GMFSS 686 Query: 1454 FYFISFYMLCAFLIINLFVAVIMDNF---DYLTRD 1485 FYFI + + ++N+F+A+ +DN LT+D Sbjct: 687 FYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKD 721 Score = 116 bits (290), Expect = 3e-25 Identities = 94/326 (28%), Positives = 163/326 (50%), Gaps = 24/326 (7%) Query: 879 AFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAED--PVQHTSFRNHILFYF 936 + F+FS +N R RI F +IL I+ + I LA E P + + L Sbjct: 74 SLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLPDGDKTPMSERLDDT 133 Query: 937 DIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKI 996 + F IF E +K+ A G HKGS+ RN +N++D +VV +++ + ++ Sbjct: 134 EPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGILA---TAGTDFDLRT 190 Query: 997 LRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLY 1056 LR +RVLRPL+ ++ L+ V++ + A+ + I ++ MFA IG++ + GK + Sbjct: 191 LRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYMGKFH 250 Query: 1057 -TCSDSSKQTEAECKGNYITYKDGEV---DHPIIQPRSWENSKF---DFDNVLAAMMALF 1109 C +S T+AE G++ K+ + W F +FDN+L A++ +F Sbjct: 251 KACFPNS--TDAEPVGDFPCGKEAPARLCEGDTECREYWPGPNFGITNFDNILFAILTVF 308 Query: 1110 TVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTF 1169 T EGW ++LY + D+ G +N+ ++FI III +FFM+N+ +G + F Sbjct: 309 QCITMEGWTDILYNTNDA----AGNTWNW-----LYFIPLIIIGSFFMLNLVLGVLSGEF 359 Query: 1170 QEQGEQ-EYKNCELDKNQRQCVEYAL 1194 ++ E+ E + L ++Q +E L Sbjct: 360 AKERERVENRRAFLKLRRQQQIEREL 385 Score = 83.2 bits (204), Expect = 3e-15 Identities = 70/295 (23%), Positives = 130/295 (44%), Gaps = 66/295 (22%) Query: 125 PFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLL 184 PFE I+ I N V L + D L+ + +F +F++E LK+IA+G+L Sbjct: 1472 PFEYFIMAMIALNTVVLMMKF---YDAPYEYELMLKCLNIVFTSMFSMECVLKIIAFGVL 1528 Query: 185 FHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRP 244 Y R+ WN+ DF+ V+ + ++ + + + ++ LR FR R Sbjct: 1529 ----NYFRDAWNVFDFVTVLGSITDILVTEIAETNNF---------INLSFLRLFRAARL 1575 Query: 245 LRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGI 304 ++L+ +++++L + +++ L ++ LL+ + IYAIIG+++F Sbjct: 1576 IKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVF-------------- 1621 Query: 305 ADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEG 364 ++ +DD S +H NF F A++ +F+ T E Sbjct: 1622 GNIALDDDTSI-----------------------NRHN--NFRTFLQALMLLFRSATGEA 1656 Query: 365 WTDVLYWV--NDAV---------GRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEF 408 W +++ N A G D+ + YFV+ I + SF +LNL + V+ F Sbjct: 1657 WHEIMLSCLSNQACDEQANATECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNF 1711 Score = 64.7 bits (156), Expect = 9e-10 Identities = 64/301 (21%), Positives = 118/301 (39%), Gaps = 80/301 (26%) Query: 1221 FEYLMFVLILLNTICLAMQHY---GQSCLFKIAMNILNMLFTGLFTVEMILKLIA----F 1273 FEY++ I+ N I LA++ + G ++ F G+F E +K+IA F Sbjct: 97 FEYMILATIIANCIVLALEQHLPDGDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVF 156 Query: 1274 KPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRV 1333 Y + WN D ++V+ I+ A T+ + + R RV Sbjct: 157 HKGSYLRNGWNVMDFVVVLTGILATAGTDFD--------------------LRTLRAVRV 196 Query: 1334 MRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQV----FGKIALND 1389 +R +KL+S ++ +L + +K+ L + LL+ ++A+IG++ F K + Sbjct: 197 LRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYMGKFHKACFPN 256 Query: 1390 TTEINRNN-------------------------------NFQTFPQAVLLLFRCATGEAW 1418 +T+ NF A+L +F+C T E W Sbjct: 257 STDAEPVGDFPCGKEAPARLCEGDTECREYWPGPNFGITNFDNILFAILTVFQCITMEGW 316 Query: 1419 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN 1478 DI+ N+ + G+++ YFI ++ +F ++NL + V+ Sbjct: 317 TDILY---------------NTNDA---AGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGE 358 Query: 1479 F 1479 F Sbjct: 359 F 359 >gi|187828892 calcium channel, alpha 1A subunit isoform 4 [Homo sapiens] Length = 2506 Score = 767 bits (1981), Expect = 0.0 Identities = 404/869 (46%), Positives = 562/869 (64%), Gaps = 56/869 (6%) Query: 790 LVEKPAVGESKEEKIELKSITADGESPPATK--INMDDLQPNENEDKSPYPNPETTGEED 847 +V P+ ++ K K + PPA +N +Q N+N + P P E +E+ Sbjct: 1145 IVTNPSGTQTNSAKTARKPDHTTVDIPPACPPPLNHTVVQVNKNANPDPLPKKEEEKKEE 1204 Query: 848 EEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDTIFTNLIL 907 EE+ GP+P MP S+ FI S+ N R CH I+N F IL Sbjct: 1205 EEDDRGEDGPKP--------------MPPYSSMFILSTTNPLRRLCHYILNLRYFEMCIL 1250 Query: 908 FFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRN 967 I +SSI+LAAEDPVQ + RN++L YFD VFT +FT E+ +KM G LH+G++ R+ Sbjct: 1251 MVIAMSSIALAAEDPVQPNAPRNNVLRYFDYVFTGVFTFEMVIKMIDLGLVLHQGAYFRD 1310 Query: 968 YFNILDLLVVSVSLISFGIQSSA----INVVKILRVLRVLRPLRAINRAKGLKHVVQCVF 1023 +NILD +VVS +L++F ++ IN +K LRVLRVLRPL+ I R LK V CV Sbjct: 1311 LWNILDFIVVSGALVAFAFTGNSKGKDINTIKSLRVLRVLRPLKTIKRLPKLKAVFDCVV 1370 Query: 1024 VAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDH 1083 +++ + NI+IV L F+FA + VQLFKGK + C+D SK+ E +C+G Y+ Y+ EV Sbjct: 1371 NSLKNVFNILIVYMLFMFIFAVVAVQLFKGKFFHCTDESKEFEKDCRGKYLLYEKNEVK- 1429 Query: 1084 PIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEIS 1143 + R W+ +F +DNVL A++ LFTVST EGWP++L S+D+ E++GP YR+E+S Sbjct: 1430 --ARDREWKKYEFHYDNVLWALLTLFTVSTGEGWPQVLKHSVDATFENQGPSPGYRMEMS 1487 Query: 1144 IFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYI 1203 IF+++Y ++ FF +NIFV +I+TFQEQG++ + L+KN+R C+++A+ A+PL R++ Sbjct: 1488 IFYVVYFVVFPFFFVNIFVALIIITFQEQGDKMMEEYSLEKNERACIDFAISAKPLTRHM 1547 Query: 1204 PKNQH--QYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGL 1261 P+N+ QY++W V S FEY + +I LNTI L M+ YG S ++ A+ + N++FT L Sbjct: 1548 PQNKQSFQYRMWQFVVSPPFEYTIMAMIALNTIVLMMKFYGASVAYENALRVFNIVFTSL 1607 Query: 1262 FTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENS 1321 F++E +LK++AF +YF DAWN FD + V+GSI DI +TE N+ Sbjct: 1608 FSLECVLKVMAFGILNYFRDAWNIFDFVTVLGSITDILVTEFG---------------NN 1652 Query: 1322 RISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQV 1381 I+++F RLFR RL+KLL +G IR LLWTF++SF+ALPYV LLI MLFFIYA+IGMQV Sbjct: 1653 FINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQV 1712 Query: 1382 FGKIALN--------DTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAP 1433 FG I ++ D +I +NNF+TF QA++LLFR ATGEAW +IML+C+ GK C Sbjct: 1713 FGNIGIDVEDEDSDEDEFQITEHNNFRTFFQALMLLFRSATGEAWHNIMLSCLSGKPC-- 1770 Query: 1434 ESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHH 1493 NS CG+ FA FYF+SF LC+FL++NLFVAVIMDNF+YLTRD SILGPHH Sbjct: 1771 ---DKNSGILTRECGNEFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHH 1827 Query: 1494 LDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSD 1553 LDE+ R+WAEYDP A GR+ +LD+ +LR + PPLG GK CP RVA KRL+ M++P+ D Sbjct: 1828 LDEYVRVWAEYDPAAWGRMPYLDMYQMLRHMSPPLGLGKKCPARVAYKRLLRMDLPVADD 1887 Query: 1554 GTVMFNATLFALVRTALRIKTE---GNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGD 1610 TV FN+TL AL+RTAL IK + +Q + ELR + IW S K LD +V P Sbjct: 1888 NTVHFNSTLMALIRTALDIKIAKGGADKQQMDAELRKEMMAIWPNLSQKTLDLLVTPHKS 1947 Query: 1611 DEVTVGKFYATFLIQEYFRKFKKRKEQGL 1639 ++TVGK YA +I EY+R+ K +K Q + Sbjct: 1948 TDLTVGKIYAAMMIMEYYRQSKAKKLQAM 1976 Score = 671 bits (1731), Expect = 0.0 Identities = 383/826 (46%), Positives = 507/826 (61%), Gaps = 63/826 (7%) Query: 18 SNYGSPRPA-HANMNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTV 76 + +G PA + + AAAG+ GA S Q G G + Sbjct: 2 ARFGDEMPARYGGGGSGAAAGVVVGSGGGRGAGGSRQG-----------GQPGAQRMYKQ 50 Query: 77 SSTQRKRQQ--YGK-PKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLT 133 S QR R Y P +Q T R +L + N +R+ I EW PFE +IL T Sbjct: 51 SMAQRARTMALYNPIPVRQNCLTVNR---SLFLFSEDNVVRKYAKKITEWPPFEYMILAT 107 Query: 134 IFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRN 193 I ANC+ LA+ P+DD + L+ E F+ IF EA +K+IA G FH +YLRN Sbjct: 108 IIANCIVLALEQHLPDDDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFAFHKGSYLRN 167 Query: 194 GWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPS 253 GWN++DF++V+ G+ + + G FD++ LRA RVLRPL+LVSG+PS Sbjct: 168 GWNVMDFVVVLTGILATV----------------GTEFDLRTLRAVRVLRPLKLVSGIPS 211 Query: 254 LQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDP 313 LQVVL SI+KAM+PLL I LL+ F I+I+AIIGLE +MGK H TC+ +EG D+ E P Sbjct: 212 LQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKFHTTCF-EEGTDDIQGES-P 269 Query: 314 SPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVN 373 +PC E R C NGT C+P W+GP +GIT FDN FA+LTVFQCITMEGWTD+LY N Sbjct: 270 APCGTEEP-ARTCPNGTKCQPYWEGPNNGITQFDNILFAVLTVFQCITMEGWTDLLYNSN 328 Query: 374 DAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEED 433 DA G W W+YF+ LIIIGSFF+LNLVLGVLSGEF+KERE+ + R F KLR +QQ+E + Sbjct: 329 DASGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFAKERERVENRRAFLKLRRQQQIERE 388 Query: 434 LKGYLDWITQAEDIDPENEDEGMDEEKP----RNMSMPTSETESVNTENVAGGDIEGENC 489 L GY++WI++AE++ ++ ++ P R ++ S+T+ +N E + + Sbjct: 389 LNGYMEWISKAEEVILAEDETDGEQRHPFDALRRTTIKKSKTDLLNPEEAEDQLADIASV 448 Query: 490 G---ARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHY 546 G AR + + +K + S ++ + R R R VK+ FYW V+ LV LNTL +A HY Sbjct: 449 GSPFARASIKSAKLENSTFFHKKERRMRFYIRRMVKTQAFYWTVLSLVALNTLCVAIVHY 508 Query: 547 NQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILV 606 NQP WL++ A L LF +EM +KMY LG + YF S FN FDC V+ G I E I Sbjct: 509 NQPEWLSDFLYYAEFIFLGLFMSEMFIKMYGLGTRPYFHSSFNCFDCGVIIGSIFEVIWA 568 Query: 607 ETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFS 666 K + GISVLR +RLLRIFK+T+YW SL NLV SLLNS++SI SLL LLFLFI++F+ Sbjct: 569 VIKPGTSFGISVLRALRLLRIFKVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVFA 628 Query: 667 LLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPG 726 LLGMQLFGG+FNFDE T + FD FP +++TVFQILTGEDWN VMYDGI + GG G Sbjct: 629 LLGMQLFGGQFNFDE-GTPPTNFDTFPAAIMTVFQILTGEDWNEVMYDGIKSQGGVQ-GG 686 Query: 727 MLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERK---------- 776 M+ IYFI+L + GNY LLNVFLAIAVDNLA+A+ LT ++EEEE +K Sbjct: 687 MVFSIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEEEEAANQKLALQKAKEVA 746 Query: 777 -----KLARTASPEKKQELVEKPA--VGESKEEKIELKSITADGES 815 A + K+Q+ +KPA V E + ++ +++ A E+ Sbjct: 747 EVSPLSAANMSIAVKEQQKNQKPAKSVWEQRTSEMRKQNLLASREA 792 Score = 202 bits (513), Expect = 4e-51 Identities = 176/705 (24%), Positives = 317/705 (44%), Gaps = 120/705 (17%) Query: 80 QRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCV 139 + K+++ + + P ++ L+ NP+RR C I+ + FE+ IL+ I + + Sbjct: 1199 EEKKEEEEDDRGEDGPKPMPPYSSMFILSTTNPLRRLCHYILNLRYFEMCILMVIAMSSI 1258 Query: 140 ALAIYIPFPEDDSNATNSNLERV-EYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLL 198 ALA P NA +N+ R +Y+F +FT E +K+I GL+ H AY R+ WN+L Sbjct: 1259 ALAAEDPV---QPNAPRNNVLRYFDYVFTGVFTFEMVIKMIDLGLVLHQGAYFRDLWNIL 1315 Query: 199 DFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVL 258 DFI+V L + +K N +K+LR RVLRPL+ + +P L+ V Sbjct: 1316 DFIVVSGALVAFAFTGNSKGKDINT---------IKSLRVLRVLRPLKTIKRLPKLKAVF 1366 Query: 259 NSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGK-MHKTCYNQEGIADVPAEDDPSPCA 317 + ++ ++ + +I ++ + + I+A++ ++LF GK H T ++E D Sbjct: 1367 DCVVNSLKNVFNILIVYMLFMFIFAVVAVQLFKGKFFHCTDESKEFEKDC---------- 1416 Query: 318 LETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAV- 376 G + V + K+ ++DN +A+LT+F T EGW VL DA Sbjct: 1417 --RGKYLLYEKNEVKARDREWKKYEF-HYDNVLWALLTLFTVSTGEGWPQVLKHSVDATF 1473 Query: 377 --------GRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQ 428 R I++V ++ FF +N+ + ++ F ++ GD K+ E+ Sbjct: 1474 ENQGPSPGYRMEMSIFYVVYFVVFPFFFVNIFVALIIITFQEQ-------GD--KMMEEY 1524 Query: 429 QLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVAGGDIEGEN 488 LE++ + +D+ A KP MP Sbjct: 1525 SLEKNERACIDFAISA---------------KPLTRHMP--------------------- 1548 Query: 489 CGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQ 548 ++K S +R W V S F + ++ ++ LNT+ + + Y Sbjct: 1549 ----------QNKQSFQYRMWQ---------FVVSPPFEYTIMAMIALNTIVLMMKFYGA 1589 Query: 549 PNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVET 608 N +LF+ E +LK+ + G+ YF +N FD V G I + ILV Sbjct: 1590 SVAYENALRVFNIVFTSLFSLECVLKVMAFGILNYFRDAWNIFDFVTVLGSITD-ILVTE 1648 Query: 609 KIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLL 668 + + +S LR R R+ K+ R ++ L+ + + S +++ + LL+ + I++++ Sbjct: 1649 FGNNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAII 1708 Query: 669 GMQLFGG--------KFNFDEMQ-TRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAY 719 GMQ+FG + DE Q T + F F Q+L+ +F+ TGE W+++M + Sbjct: 1709 GMQVFGNIGIDVEDEDSDEDEFQITEHNNFRTFFQALMLLFRSATGEAWHNIMLSCLSGK 1768 Query: 720 GGPSFPGML--------VCIYFI-ILFICGNYILLNVFLAIAVDN 755 G+L YF+ +F+C ++++LN+F+A+ +DN Sbjct: 1769 PCDKNSGILTRECGNEFAYFYFVSFIFLC-SFLMLNLFVAVIMDN 1812 Score = 145 bits (366), Expect = 4e-34 Identities = 179/784 (22%), Positives = 325/784 (41%), Gaps = 160/784 (20%) Query: 480 AGGDIEGENCGARLAHRISKSKFSRYWRRWNRF-CRRKCRAAVKS-------NV------ 525 AGG +G GA+ ++ S ++ +R +N R+ C +S NV Sbjct: 33 AGGSRQGGQPGAQRMYKQSMAQRARTMALYNPIPVRQNCLTVNRSLFLFSEDNVVRKYAK 92 Query: 526 -------FYWLVIFLVFLNTLTIASEHY---NQPNWLTEVQDTANKALLALFTAEMLLKM 575 F ++++ + N + +A E + + ++E D + +F E +K+ Sbjct: 93 KITEWPPFEYMILATIIANCIVLALEQHLPDDDKTPMSERLDDTEPYFIGIFCFEAGIKI 152 Query: 576 YSLGLQ----AYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKIT 631 +LG +Y + +N D VV GIL T+ E + LR VR+LR K+ Sbjct: 153 IALGFAFHKGSYLRNGWNVMDFVVVLTGILATVGTE------FDLRTLRAVRVLRPLKLV 206 Query: 632 RYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNF-------DEMQT 684 SL ++ S++ ++ + + LLLF I+IF+++G++ + GKF+ D++Q Sbjct: 207 SGIPSLQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKFHTTCFEEGTDDIQG 266 Query: 685 RR------------------------------STFDNFPQSLLTVFQILTGEDWNSVMYD 714 + FDN ++LTVFQ +T E W ++Y+ Sbjct: 267 ESPAPCGTEEPARTCPNGTKCQPYWEGPNNGITQFDNILFAVLTVFQCITMEGWTDLLYN 326 Query: 715 GIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKE 774 A G +YFI L I G++ +LN+ L + A +E+E Sbjct: 327 SNDASGNT-----WNWLYFIPLIIIGSFFMLNLVLGVLSGEFA-------------KERE 368 Query: 775 RKKLARTASPEKKQELVEKPAVGE----SKEEKIELKSITADGESP-PATKINMDDLQPN 829 R + R ++Q+ +E+ G SK E++ L DGE P + ++ Sbjct: 369 RVENRRAFLKLRRQQQIERELNGYMEWISKAEEVILAEDETDGEQRHPFDALRRTTIK-- 426 Query: 830 ENEDKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRF 889 + K+ NPE ED+ VG P + +K + E S FF R Sbjct: 427 --KSKTDLLNPEEA--EDQLADIASVGS---PFARASIKSAKL---ENSTFF-HKKERRM 475 Query: 890 RLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIA 949 R R+V F +L + L+++ +A Q + + L+Y + +F +F E+ Sbjct: 476 RFYIRRMVKTQAFYWTVLSLVALNTLCVAIVHYNQ-PEWLSDFLYYAEFIFLGLFMSEMF 534 Query: 950 LKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISF---GIQSSAINVVKILRVLRVLRPL 1006 +KM G + + FN D V+ S+ I+ + +LR LR+LR Sbjct: 535 IKMYGLGT----RPYFHSSFNCFDCGVIIGSIFEVIWAVIKPGTSFGISVLRALRLLRIF 590 Query: 1007 RAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTE 1066 + L+++V + ++++I +++ + L +FA +G+QLF G+ + + + T Sbjct: 591 KVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQ-FNFDEGTPPT- 648 Query: 1067 AECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSID 1126 +FD AA+M +F + T E W E++Y I Sbjct: 649 ------------------------------NFDTFPAAIMTVFQILTGEDWNEVMYDGIK 678 Query: 1127 SHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVI--------VTFQEQGEQEYK 1178 S +G + SI+FI+ + + ++N+F+ + +T EQ E+E Sbjct: 679 SQGGVQGGMV-----FSIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEEEEAA 733 Query: 1179 NCEL 1182 N +L Sbjct: 734 NQKL 737 Score = 114 bits (285), Expect = 1e-24 Identities = 96/331 (29%), Positives = 162/331 (48%), Gaps = 33/331 (9%) Query: 879 AFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAED--PVQHTSFRNHILFYF 936 + F+FS +N R +I F +IL I+ + I LA E P + + L Sbjct: 77 SLFLFSEDNVVRKYAKKITEWPPFEYMILATIIANCIVLALEQHLPDDDKTPMSERLDDT 136 Query: 937 DIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLI-SFGIQSSAINVVK 995 + F IF E +K+ A G HKGS+ RN +N++D +VV ++ + G + ++ Sbjct: 137 EPYFIGIFCFEAGIKIIALGFAFHKGSYLRNGWNVMDFVVVLTGILATVGTEFD----LR 192 Query: 996 ILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKL 1055 LR +RVLRPL+ ++ L+ V++ + A+ + I ++ +FA IG++ + GK Sbjct: 193 TLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKF 252 Query: 1056 YT------CSDSSKQTEAEC--KGNYITYKDGEVDHPIIQPRSWE---NSKFDFDNVLAA 1104 +T D ++ A C + T +G P WE N FDN+L A Sbjct: 253 HTTCFEEGTDDIQGESPAPCGTEEPARTCPNGTKCQPY-----WEGPNNGITQFDNILFA 307 Query: 1105 MMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGF 1164 ++ +F T EGW +LLY S D+ G +N+ ++FI III +FFM+N+ +G Sbjct: 308 VLTVFQCITMEGWTDLLYNSNDA----SGNTWNW-----LYFIPLIIIGSFFMLNLVLGV 358 Query: 1165 VIVTFQEQGEQ-EYKNCELDKNQRQCVEYAL 1194 + F ++ E+ E + L ++Q +E L Sbjct: 359 LSGEFAKERERVENRRAFLKLRRQQQIEREL 389 Score = 113 bits (282), Expect = 2e-24 Identities = 74/294 (25%), Positives = 138/294 (46%), Gaps = 42/294 (14%) Query: 1195 KARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNIL 1254 K R +R YI + +V + F + + L+ LNT+C+A+ HY Q + Sbjct: 471 KERRMRFYIRR---------MVKTQAFYWTVLSLVALNTLCVAIVHYNQPEWLSDFLYYA 521 Query: 1255 NMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPS 1314 +F GLF EM +K+ + YF ++N FD +++GSI ++ + P Sbjct: 522 EFIFLGLFMSEMFIKMYGLGTRPYFHSSFNCFDCGVIIGSIFEVIWAVIKP--------- 572 Query: 1315 MNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIY 1374 + I+ R R++R+ K+ +R L+ + + S +++ + L+ + ++ Sbjct: 573 -----GTSFGISVLRALRLLRIFKVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVF 627 Query: 1375 AVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPE 1434 A++GMQ+FG + E NF TFP A++ +F+ TGE W ++M Sbjct: 628 ALLGMQLFG--GQFNFDEGTPPTNFDTFPAAIMTVFQILTGEDWNEVMY----------- 674 Query: 1435 SEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNF---DYLTRD 1485 ++G G F++ YFI + + ++N+F+A+ +DN LT+D Sbjct: 675 --DGIKSQGGVQGGMVFSI-YFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKD 725 Score = 94.4 bits (233), Expect = 1e-18 Identities = 79/311 (25%), Positives = 143/311 (45%), Gaps = 41/311 (13%) Query: 514 RRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPNW-LTEVQDTANKALLALFTAEML 572 RR C + F ++ ++ ++++ +A+E QPN V + +FT EM+ Sbjct: 1233 RRLCHYILNLRYFEMCILMVIAMSSIALAAEDPVQPNAPRNNVLRYFDYVFTGVFTFEMV 1292 Query: 573 LKMYSLGLQ----AYFVSLFNRFDCFVVCGGILETILVETKIMSPLG-ISVLRCVRLLRI 627 +KM LGL AYF L+N D VV G ++ + I LR +R+LR Sbjct: 1293 IKMIDLGLVLHQGAYFRDLWNILDFIVVSGALVAFAFTGNSKGKDINTIKSLRVLRVLRP 1352 Query: 628 FKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKF---------- 677 K + L + ++NS++++ ++L++ LF+ IF+++ +QLF GKF Sbjct: 1353 LKTIKRLPKLKAVFDCVVNSLKNVFNILIVYMLFMFIFAVVAVQLFKGKFFHCTDESKEF 1412 Query: 678 -----------NFDEMQTRRST-------FDNFPQSLLTVFQILTGEDWNSVM---YDGI 716 +E++ R +DN +LLT+F + TGE W V+ D Sbjct: 1413 EKDCRGKYLLYEKNEVKARDREWKKYEFHYDNVLWALLTLFTVSTGEGWPQVLKHSVDAT 1472 Query: 717 MAYGGPSFPG--MLVCIYFIILFICGNYILLNVFLAIAVDNLAD-AESLTSAQKEEEEEK 773 GPS PG M + I++++ F+ + +N+F+A+ + + + + E+ E+ Sbjct: 1473 FENQGPS-PGYRMEMSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKMMEEYSLEKNER 1531 Query: 774 ERKKLARTASP 784 A +A P Sbjct: 1532 ACIDFAISAKP 1542 Score = 82.0 bits (201), Expect = 6e-15 Identities = 73/297 (24%), Positives = 130/297 (43%), Gaps = 62/297 (20%) Query: 125 PFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLL 184 PFE I+ I N + L + S A + L +F +F++E LKV+A+G+L Sbjct: 1566 PFEYTIMAMIALNTIVLMMKF---YGASVAYENALRVFNIVFTSLFSLECVLKVMAFGIL 1622 Query: 185 FHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRP 244 Y R+ WN+ DF+ V+ + ++ + G N + ++ LR FR R Sbjct: 1623 ----NYFRDAWNIFDFVTVLGSITDILVTEF----GNNFI-------NLSFLRLFRAARL 1667 Query: 245 LRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGI 304 ++L+ +++++L + +++ L ++ LL+ + IYAIIG+++F GI Sbjct: 1668 IKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVF---------GNIGI 1718 Query: 305 ADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEG 364 DV ED T H NF F A++ +F+ T E Sbjct: 1719 -DVEDEDSDEDEFQITEH---------------------NNFRTFFQALMLLFRSATGEA 1756 Query: 365 WTDVLY-------------WVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEF 408 W +++ + G ++ + YFV+ I + SF +LNL + V+ F Sbjct: 1757 WHNIMLSCLSGKPCDKNSGILTRECGNEFAYFYFVSFIFLCSFLMLNLFVAVIMDNF 1813 Score = 62.0 bits (149), Expect = 6e-09 Identities = 69/302 (22%), Positives = 118/302 (39%), Gaps = 81/302 (26%) Query: 1221 FEYLMFVLILLNTICLAMQHY---GQSCLFKIAMNILNMLFTGLFTVEMILKLIA----F 1273 FEY++ I+ N I LA++ + ++ F G+F E +K+IA F Sbjct: 100 FEYMILATIIANCIVLALEQHLPDDDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFAF 159 Query: 1274 KPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRV 1333 Y + WN D ++V+ I+ TE + + R RV Sbjct: 160 HKGSYLRNGWNVMDFVVVLTGILATVGTEFD--------------------LRTLRAVRV 199 Query: 1334 MRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVF-GKI------- 1385 +R +KL+S ++ +L + +K+ L + LL+ I+A+IG++ + GK Sbjct: 200 LRPLKLVSGIPSLQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKFHTTCFEE 259 Query: 1386 ----------ALNDTTEINR---------------NNNFQTFPQ---AVLLLFRCATGEA 1417 A T E R NN F AVL +F+C T E Sbjct: 260 GTDDIQGESPAPCGTEEPARTCPNGTKCQPYWEGPNNGITQFDNILFAVLTVFQCITMEG 319 Query: 1418 WQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMD 1477 W D++ NS + G+++ YFI ++ +F ++NL + V+ Sbjct: 320 WTDLLY---------------NSNDAS---GNTWNWLYFIPLIIIGSFFMLNLVLGVLSG 361 Query: 1478 NF 1479 F Sbjct: 362 EF 363 >gi|53832005 calcium channel, voltage-dependent, R type, alpha 1E subunit [Homo sapiens] Length = 2270 Score = 745 bits (1923), Expect = 0.0 Identities = 391/833 (46%), Positives = 546/833 (65%), Gaps = 38/833 (4%) Query: 833 DKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQ 892 D P E EDEEE E + + +E M S+ FIFS+ N R Sbjct: 1093 DGEASPLKEAEIREDEEEVEKKKQKKEK-------RETGKAMVPHSSMFIFSTTNPIRRA 1145 Query: 893 CHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKM 952 CH IVN F IL I SSI+LAAEDPV S RN +L YFD VFT +FT E+ +KM Sbjct: 1146 CHYIVNLRYFEMCILLVIAASSIALAAEDPVLTNSERNKVLRYFDYVFTGVFTFEMVIKM 1205 Query: 953 TAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSA-------INVVKILRVLRVLRP 1005 G L GS+ R+ +NILD +VV +L++F + ++ I +K LRVLRVLRP Sbjct: 1206 IDQGLILQDGSYFRDLWNILDFVVVVGALVAFALANALGTNKGRDIKTIKSLRVLRVLRP 1265 Query: 1006 LRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQT 1065 L+ I R LK V CV +++ + NI+IV L F+FA I VQLFKGK + C+DSSK T Sbjct: 1266 LKTIKRLPKLKAVFDCVVTSLKNVFNILIVYKLFMFIFAVIAVQLFKGKFFYCTDSSKDT 1325 Query: 1066 EAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSI 1125 E EC GNY+ ++ +++ ++ R W+ +F +DN++ A++ LFTVST EGWP++L S+ Sbjct: 1326 EKECIGNYVDHEKNKME---VKGREWKRHEFHYDNIIWALLTLFTVSTGEGWPQVLQHSV 1382 Query: 1126 DSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKN 1185 D ED+GP + R+E+SIF+++Y ++ FF +NIFV +I+TFQEQG++ + C L+KN Sbjct: 1383 DVTEEDRGPSRSNRMEMSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKMMEECSLEKN 1442 Query: 1186 QRQCVEYALKARPLRRYIPKNQH--QYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQ 1243 +R C+++A+ A+PL RY+P+N+H QY+VW+ V S FEY + +I LNT+ L M++Y Sbjct: 1443 ERACIDFAISAKPLTRYMPQNRHTFQYRVWHFVVSPSFEYTIMAMIALNTVVLMMKYYSA 1502 Query: 1244 SCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEV 1303 C +++A+ LN+ FT +F++E +LK+IAF +YF D WN FD + V+GSI +I +T+ Sbjct: 1503 PCTYELALKYLNIAFTMVFSLECVLKVIAFGFLNYFRDTWNIFDFITVIGSITEIILTD- 1561 Query: 1304 NPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYV 1363 S +N S +++F +LFR RL+KLL +G IR LLWTF++SF+ALPYV Sbjct: 1562 --------SKLVNT---SGFNMSFLKLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYV 1610 Query: 1364 ALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIML 1423 LLI MLFFIYA+IGMQVFG I L++ + INR+NNF++F +++LLFR ATGEAWQ+IML Sbjct: 1611 CLLIAMLFFIYAIIGMQVFGNIKLDEESHINRHNNFRSFFGSLMLLFRSATGEAWQEIML 1670 Query: 1424 ACMPGKKCAPESE-PSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYL 1482 +C+ K C P++ PS E E CG+ A YF+SF C+FL++NLFVAVIMDNF+YL Sbjct: 1671 SCLGEKGCEPDTTAPSGQNENER-CGTDLAYVYFVSFIFFCSFLMLNLFVAVIMDNFEYL 1729 Query: 1483 TRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKR 1542 TRD SILGPHHLDEF R+WAEYD A GRI + ++ +L + PPLG GK CP +VA KR Sbjct: 1730 TRDSSILGPHHLDEFVRVWAEYDRAACGRIHYTEMYEMLTLMSPPLGLGKRCPSKVAYKR 1789 Query: 1543 LVSMNMPLNSDGTVMFNATLFALVRTALRIKTE---GNLEQANEELRAIIKKIWKRTSMK 1599 LV MNMP+ D TV F +TL AL+RTAL IK + +Q + EL+ IW S K Sbjct: 1790 LVLMNMPVAEDMTVHFTSTLMALIRTALDIKIAKGGADRQQLDSELQKETLAIWPHLSQK 1849 Query: 1600 LLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ 1652 +LD +VP ++TVGK YA +I +Y+++ K +K++ + Q+NA Q Sbjct: 1850 MLDLLVPMPKASDLTVGKIYAAMMIMDYYKQSKVKKQRQQL--EEQKNAPMFQ 1900 Score = 630 bits (1626), Expect = e-180 Identities = 359/754 (47%), Positives = 468/754 (62%), Gaps = 35/754 (4%) Query: 60 RQAKLMGSAGNATISTVSSTQRKRQQ--YGK-PKKQGSTTATRPPRALLCLTLKNPIRRA 116 RQ + ++G A + QR R Y P +Q T R +L N +R+ Sbjct: 25 RQGTPVPASGQAAAYKQTKAQRARTMALYNPIPVRQNCFTVNR---SLFIFGEDNIVRKY 81 Query: 117 CISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFL 176 +++W PFE +IL TI ANC+ LA+ PEDD + LE+ E F+ IF EA + Sbjct: 82 AKKLIDWPPFEYMILATIIANCIVLALEQHLPEDDKTPMSRRLEKTEPYFIGIFCFEAGI 141 Query: 177 KVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKAL 236 K++A G +FH +YLRNGWN++DFI+V+ G+ AT N D++ L Sbjct: 142 KIVALGFIFHKGSYLRNGWNVMDFIVVLSGIL------ATAGTHFNT------HVDLRTL 189 Query: 237 RAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHK 296 RA RVLRPL+LVSG+PSLQ+VL SI+KAMVPLL I LL+ F I+++AIIGLE + GK+H+ Sbjct: 190 RAVRVLRPLKLVSGIPSLQIVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYSGKLHR 249 Query: 297 TCY-NQEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLT 355 C+ N GI + D P PC ++ C G CK W GP GIT FDN FA+LT Sbjct: 250 ACFMNNSGILE--GFDPPHPCGVQG-----CPAGYECKD-WIGPNDGITQFDNILFAVLT 301 Query: 356 VFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKA 415 VFQCITMEGWT VLY NDA+G W W+YF+ LIIIGSFFVLNLVLGVLSGEF+KERE+ Sbjct: 302 VFQCITMEGWTTVLYNTNDALGATWNWLYFIPLIIIGSFFVLNLVLGVLSGEFAKERERV 361 Query: 416 KARGDFQKLREKQQLEEDLKGYLDWITQAEDI--DPENEDEGMDE-EKPRNMSMPTSETE 472 + R F KLR +QQ+E +L GY WI +AE++ EN++ G E R ++ S TE Sbjct: 362 ENRRAFMKLRRQQQIERELNGYRAWIDKAEEVMLAEENKNAGTSALEVLRRATIKRSRTE 421 Query: 473 SVNTENVAGGDIEGENCGARLAHRISKSKFS---RYWRRWNRFCRRKCRAAVKSNVFYWL 529 ++ ++ ++ + G LA KS Y+R R R R VKS VFYW+ Sbjct: 422 AMTRDSSDEHCVDISSVGTPLARASIKSAKVDGVSYFRHKERLLRISIRHMVKSQVFYWI 481 Query: 530 VIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFN 589 V+ LV LNT +A H+NQP WLT + A L LF EM LKMY +G + YF S FN Sbjct: 482 VLSLVALNTACVAIVHHNQPQWLTHLLYYAEFLFLGLFLLEMSLKMYGMGPRLYFHSSFN 541 Query: 590 RFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVR 649 FD V G I E + + + GISVLR +RLLRIFKIT+YW SL NLV SL++S++ Sbjct: 542 CFDFGVTVGSIFEVVWAIFRPGTSFGISVLRALRLLRIFKITKYWASLRNLVVSLMSSMK 601 Query: 650 SIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWN 709 SI SLL LLFLFI++F+LLGMQLFGG+FNF++ T + FD FP +++TVFQILTGEDWN Sbjct: 602 SIISLLFLLFLFIVVFALLGMQLFGGRFNFND-GTPSANFDTFPAAIMTVFQILTGEDWN 660 Query: 710 SVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEE 769 VMY+GI + GG S GM IYFI+L + GNY LLNVFLAIAVDNLA+A+ LT ++EE Sbjct: 661 EVMYNGIRSQGGVS-SGMWSAIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEE 719 Query: 770 EEEKERKKLARTASPEKKQELVEKPAVGESKEEK 803 EE +K + A P++ + + Sbjct: 720 EEAFNQKHALQKAKEVSPMSAPNMPSIERDRRRR 753 Score = 220 bits (561), Expect = 1e-56 Identities = 185/707 (26%), Positives = 329/707 (46%), Gaps = 124/707 (17%) Query: 80 QRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCV 139 ++K+Q K +K+ + A P ++ + NPIRRAC IV + FE+ ILL I A+ + Sbjct: 1112 EKKKQ---KKEKRETGKAMVPHSSMFIFSTTNPIRRACHYIVNLRYFEMCILLVIAASSI 1168 Query: 140 ALAIYIPFPEDDSNATNSNLERV----EYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGW 195 ALA +D TNS +V +Y+F +FT E +K+I GL+ +Y R+ W Sbjct: 1169 ALAA------EDPVLTNSERNKVLRYFDYVFTGVFTFEMVIKMIDQGLILQDGSYFRDLW 1222 Query: 196 NLLDFIIVVVGLFSAILEQATKADGANALG-GKGAGF-DVKALRAFRVLRPLRLVSGVPS 253 N+LDF++VV L + L ANALG KG +K+LR RVLRPL+ + +P Sbjct: 1223 NILDFVVVVGALVAFAL--------ANALGTNKGRDIKTIKSLRVLRVLRPLKTIKRLPK 1274 Query: 254 LQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDP 313 L+ V + ++ ++ + +I ++ + I+A+I ++LF GK C + ++D Sbjct: 1275 LKAVFDCVVTSLKNVFNILIVYKLFMFIFAVIAVQLFKGKFF-YCTDS-------SKDTE 1326 Query: 314 SPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVN 373 C G+ + + G + +H ++DN +A+LT+F T EGW VL Sbjct: 1327 KEC---IGNYVDHEKNKMEVKGREWKRHEF-HYDNIIWALLTLFTVSTGEGWPQVLQHSV 1382 Query: 374 DAVGRD---------WPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKL 424 D D I++V ++ FF +N+ + ++ F ++ GD K+ Sbjct: 1383 DVTEEDRGPSRSNRMEMSIFYVVYFVVFPFFFVNIFVALIIITFQEQ-------GD--KM 1433 Query: 425 REKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVAGGDI 484 E+ LE++ + +D+ A KP MP Sbjct: 1434 MEECSLEKNERACIDFAISA---------------KPLTRYMP----------------- 1461 Query: 485 EGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASE 544 +++ + +R W+ V S F + ++ ++ LNT+ + + Sbjct: 1462 --------------QNRHTFQYRVWH---------FVVSPSFEYTIMAMIALNTVVLMMK 1498 Query: 545 HYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETI 604 +Y+ P N A +F+ E +LK+ + G YF +N FD V G I E I Sbjct: 1499 YYSAPCTYELALKYLNIAFTMVFSLECVLKVIAFGFLNYFRDTWNIFDFITVIGSITEII 1558 Query: 605 LVETKIMSPLG--ISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFI 662 L ++K+++ G +S L+ R R+ K+ R ++ L+ + + S +++ + LL+ + Sbjct: 1559 LTDSKLVNTSGFNMSFLKLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLF 1618 Query: 663 IIFSLLGMQLFGG-KFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG- 720 I++++GMQ+FG K + + R + F +F SL+ +F+ TGE W +M + G Sbjct: 1619 FIYAIIGMQVFGNIKLDEESHINRHNNFRSFFGSLMLLFRSATGEAWQEIMLSCLGEKGC 1678 Query: 721 -----GPSFPGM-------LVCIYFIILFICGNYILLNVFLAIAVDN 755 PS L +YF+ ++++LN+F+A+ +DN Sbjct: 1679 EPDTTAPSGQNENERCGTDLAYVYFVSFIFFCSFLMLNLFVAVIMDN 1725 Score = 195 bits (495), Expect = 5e-49 Identities = 172/698 (24%), Positives = 305/698 (43%), Gaps = 141/698 (20%) Query: 879 AFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAED--PVQHTSFRNHILFYF 936 + FIF +N R ++++ F +IL I+ + I LA E P + + L Sbjct: 68 SLFIFGEDNIVRKYAKKLIDWPPFEYMILATIIANCIVLALEQHLPEDDKTPMSRRLEKT 127 Query: 937 DIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVV-SVSLISFGIQSSAINVVK 995 + F IF E +K+ A G HKGS+ RN +N++D +VV S L + G + ++ Sbjct: 128 EPYFIGIFCFEAGIKIVALGFIFHKGSYLRNGWNVMDFIVVLSGILATAGTHFNTHVDLR 187 Query: 996 ILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKL 1055 LR +RVLRPL+ ++ L+ V++ + A+ + I ++ MFA IG++ + GKL Sbjct: 188 TLRAVRVLRPLKLVSGIPSLQIVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYSGKL 247 Query: 1056 YTCSDSSKQTEAECKGNYITYKDG-EVDHPI--------IQPRSW---ENSKFDFDNVLA 1103 + C N +G + HP + + W + FDN+L Sbjct: 248 HRA----------CFMNNSGILEGFDPPHPCGVQGCPAGYECKDWIGPNDGITQFDNILF 297 Query: 1104 AMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVG 1163 A++ +F T EGW +LY + D+ G +N+ ++FI III +FF++N+ +G Sbjct: 298 AVLTVFQCITMEGWTTVLYNTNDA----LGATWNW-----LYFIPLIIIGSFFVLNLVLG 348 Query: 1164 ------------------FVIVTFQEQGEQEYKNCEL----------------------- 1182 F+ + Q+Q E+E Sbjct: 349 VLSGEFAKERERVENRRAFMKLRRQQQIERELNGYRAWIDKAEEVMLAEENKNAGTSALE 408 Query: 1183 -----------------DKNQRQCVEYALKARPLRRYIPKN---------QHQYK----- 1211 D + CV+ + PL R K+ +H+ + Sbjct: 409 VLRRATIKRSRTEAMTRDSSDEHCVDISSVGTPLARASIKSAKVDGVSYFRHKERLLRIS 468 Query: 1212 VWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLI 1271 + ++V S F +++ L+ LNT C+A+ H+ Q + LF GLF +EM LK+ Sbjct: 469 IRHMVKSQVFYWIVLSLVALNTACVAIVHHNQPQWLTHLLYYAEFLFLGLFLLEMSLKMY 528 Query: 1272 AFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLF 1331 P+ YF ++N FD + VGSI ++ P + I+ R Sbjct: 529 GMGPRLYFHSSFNCFDFGVTVGSIFEVVWAIFRP--------------GTSFGISVLRAL 574 Query: 1332 RVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVF-GKIALNDT 1390 R++R+ K+ +R L+ + + S +++ + L+ + ++A++GMQ+F G+ ND Sbjct: 575 RLLRIFKITKYWASLRNLVVSLMSSMKSIISLLFLLFLFIVVFALLGMQLFGGRFNFNDG 634 Query: 1391 TEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSS 1450 T + NF TFP A++ +F+ TGE W ++M + ++G G Sbjct: 635 TP---SANFDTFPAAIMTVFQILTGEDWNEVMYNGI-------------RSQGGVSSG-M 677 Query: 1451 FAVFYFISFYMLCAFLIINLFVAVIMDNF---DYLTRD 1485 ++ YFI + + ++N+F+A+ +DN LT+D Sbjct: 678 WSAIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKD 715 Score = 135 bits (340), Expect = 4e-31 Identities = 154/731 (21%), Positives = 303/731 (41%), Gaps = 140/731 (19%) Query: 526 FYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKA---LLALFTAEMLLKMYSLGL-- 580 F ++++ + N + +A E + + T + K + +F E +K+ +LG Sbjct: 91 FEYMILATIIANCIVLALEQHLPEDDKTPMSRRLEKTEPYFIGIFCFEAGIKIVALGFIF 150 Query: 581 --QAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLS 638 +Y + +N D VV GIL T T + + + LR VR+LR K+ SL Sbjct: 151 HKGSYLRNGWNVMDFIVVLSGILAT--AGTHFNTHVDLRTLRAVRVLRPLKLVSGIPSLQ 208 Query: 639 NLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFN-------------FDEMQTR 685 ++ S++ ++ + + LLLF I++F+++G++ + GK + FD Sbjct: 209 IVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYSGKLHRACFMNNSGILEGFDPPHPC 268 Query: 686 R--------------------STFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFP 725 + FDN ++LTVFQ +T E W +V+Y+ A G Sbjct: 269 GVQGCPAGYECKDWIGPNDGITQFDNILFAVLTVFQCITMEGWTTVLYNTNDALGAT--- 325 Query: 726 GMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPE 785 +YFI L I G++ +LN+ L + A +E+ER + R Sbjct: 326 --WNWLYFIPLIIIGSFFVLNLVLGVLSGEFA-------------KERERVENRRAFMKL 370 Query: 786 KKQELVEKPAVGE----SKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNPE 841 ++Q+ +E+ G K E++ L + + + ++ + E + Sbjct: 371 RRQQQIERELNGYRAWIDKAEEVMLAEENKNAGTSALEVLRRATIKRSRTEAMT------ 424 Query: 842 TTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDTI 901 + +E + + PL+ +K V + R+ +V + Sbjct: 425 ---RDSSDEHCVDISSVGTPLARASIKSAKVD----GVSYFRHKERLLRISIRHMVKSQV 477 Query: 902 FTNLILFFILLSSISLAAEDPVQHTS--FRNHILFYFDIVFTTIFTIEIALKMTAYGAFL 959 F ++L + L++ +A V H + H+L+Y + +F +F +E++LKM G L Sbjct: 478 FYWIVLSLVALNTACVAI---VHHNQPQWLTHLLYYAEFLFLGLFLLEMSLKMYGMGPRL 534 Query: 960 HKGSFCRNYFNILD--LLVVSVSLISFGIQSSAINV-VKILRVLRVLRPLRAINRAKGLK 1016 + + FN D + V S+ + + I + + +LR LR+LR + L+ Sbjct: 535 ----YFHSSFNCFDFGVTVGSIFEVVWAIFRPGTSFGISVLRALRLLRIFKITKYWASLR 590 Query: 1017 HVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITY 1076 ++V + ++++I +++ + L +FA +G+QLF G+ + Sbjct: 591 NLVVSLMSSMKSIISLLFLLFLFIVVFALLGMQLFGGRF-------------------NF 631 Query: 1077 KDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIY 1136 DG +FD AA+M +F + T E W E++Y I S ++ Sbjct: 632 NDG-------------TPSANFDTFPAAIMTVFQILTGEDWNEVMYNGIRSQGGVSSGMW 678 Query: 1137 NYRVEISIFFIIYIIIIAFFMMNIFVGFVI--------VTFQEQGEQEYKNCELDKNQRQ 1188 + +I+FI+ + + ++N+F+ + +T EQ E+E NQ+ Sbjct: 679 S-----AIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEEEE------AFNQKH 727 Query: 1189 CVEYALKARPL 1199 ++ A + P+ Sbjct: 728 ALQKAKEVSPM 738 Score = 81.3 bits (199), Expect = 1e-14 Identities = 72/302 (23%), Positives = 131/302 (43%), Gaps = 74/302 (24%) Query: 126 FEIIILLTIFANCVALAI-YIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLL 184 FE I+ I N V L + Y P A L+ + F ++F++E LKVIA+G L Sbjct: 1480 FEYTIMAMIALNTVVLMMKYYSAPCTYELA----LKYLNIAFTMVFSLECVLKVIAFGFL 1535 Query: 185 FHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRP 244 Y R+ WN+ DFI V+ + IL + + + GF++ L+ FR R Sbjct: 1536 ----NYFRDTWNIFDFITVIGSITEIILTDSKLVNTS--------GFNMSFLKLFRAARL 1583 Query: 245 LRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGI 304 ++L+ +++++L + +++ L ++ LL+ + IYAIIG+++F Sbjct: 1584 IKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVF-------------- 1629 Query: 305 ADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEG 364 ++ ++ E+ R NF +F +++ +F+ T E Sbjct: 1630 GNIKLDE-------ESHINRH------------------NNFRSFFGSLMLLFRSATGEA 1664 Query: 365 WTDVLYWV------------------NDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSG 406 W +++ N+ G D ++YFV+ I SF +LNL + V+ Sbjct: 1665 WQEIMLSCLGEKGCEPDTTAPSGQNENERCGTDLAYVYFVSFIFFCSFLMLNLFVAVIMD 1724 Query: 407 EF 408 F Sbjct: 1725 NF 1726 >gi|38505290 voltage-dependent calcium channel alpha 1G subunit isoform 13 [Homo sapiens] Length = 2243 Score = 332 bits (851), Expect = 2e-90 Identities = 225/787 (28%), Positives = 407/787 (51%), Gaps = 69/787 (8%) Query: 767 KEEEEEKERKKLARTASPEKKQELVEKPAVGE-SKEEKIELKSI--TADGESPPATKINM 823 ++EEE E ++ + S + + +E+ A + +++ + TA G + + Sbjct: 1117 QDEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDC 1176 Query: 824 DDLQPNENEDKSPYPN-PETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFI 882 + + ++ P+ P G++ ++E + G R R L + SA+ I Sbjct: 1177 NGKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAY-I 1235 Query: 883 FSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDP-VQHTSFRNHILFYFDIVFT 941 F +RFRL CHRI+ +F +++L I L+ I++A E P + S L + +FT Sbjct: 1236 FPPQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFT 1295 Query: 942 TIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQ------SSAINVVK 995 +F E+ +K+ A G + ++ R+ +N+LD L+V +S+I + + + +++ Sbjct: 1296 AVFLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLR 1355 Query: 996 ILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKL 1055 +LR+LR LRPLR I+RA+GLK VV+ + +++ IGNIV++ +F +GVQLFKGK Sbjct: 1356 VLRLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKF 1415 Query: 1056 YTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFE 1115 + C + IT K + W K++FDN+ A+M+LF +++ + Sbjct: 1416 FVCQGEDTRN--------ITNKSDCAEASY----RWVRHKYNFDNLGQALMSLFVLASKD 1463 Query: 1116 GWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTF----QE 1171 GW +++Y +D+ D+ PI N+ + ++FI +++I+AFF++N+FVG V+ F Q Sbjct: 1464 GWVDIMYDGLDAVGVDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQH 1523 Query: 1172 QGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILL 1231 Q E+E + E +K R+ + KA+ Y ++ + V ++ S Y + + +I L Sbjct: 1524 QEEEEARRRE-EKRLRRLEKKRRKAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGVIGL 1582 Query: 1232 NTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIV 1291 N + +AM+HY Q + A+ I N +FT +F +E + KL+AF + +F D WN D IV Sbjct: 1583 NVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDLAIV 1642 Query: 1292 VGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLW 1351 + SI+ I + E+ +P++ I R+ R+ R++KLL G+R LL Sbjct: 1643 LLSIMGITLEEIEVNASLPINPTI---------IRIMRVLRIARVLKLLKMAVGMRALLD 1693 Query: 1352 TFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDT---TEINRNNNFQTFPQAVLL 1408 T +++ + + LL ++LFFI+A +G+++FG + ++T + R+ F+ F A L Sbjct: 1694 TVMQALPQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLT 1753 Query: 1409 LFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLII 1468 LFR +TG+ W IM + + C ES N+ + YF+SF + F+++ Sbjct: 1754 LFRVSTGDNWNGIMKDTL--RDCDQESTCYNTV---------ISPIYFVSFVLTAQFVLV 1802 Query: 1469 NLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPL 1528 N+ +AV+M HL+E + A+ + E + ++ L++ TL + PL Sbjct: 1803 NVVIAVLM---------------KHLEESNK-EAKEEAELEAELE-LEMKTLSPQPHSPL 1845 Query: 1529 GFGKLCP 1535 G L P Sbjct: 1846 GSPFLWP 1852 Score = 240 bits (613), Expect = 9e-63 Identities = 183/698 (26%), Positives = 325/698 (46%), Gaps = 116/698 (16%) Query: 114 RRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVE 173 R C I+ K F+ ++L+ IF NC+ +A+ P D +A L Y+F +F E Sbjct: 1243 RLLCHRIITHKMFDHVVLVIIFLNCITIAMERP-KIDPHSAERIFLTLSNYIFTAVFLAE 1301 Query: 174 AFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDV 233 +KV+A G F AYLR+ WN+LD ++V++ + ++ + + G LG + Sbjct: 1302 MTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDS-GTKILGM------L 1354 Query: 234 KALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGK 293 + LR R LRPLR++S L++V+ +++ ++ P+ +I ++ II+ I+G++LF GK Sbjct: 1355 RVLRLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGK 1414 Query: 294 MHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAM 353 C + D + S CA + W K+ NFDN A+ Sbjct: 1415 FF-VCQGE----DTRNITNKSDCAEASYR-------------WVRHKY---NFDNLGQAL 1453 Query: 354 LTVFQCITMEGWTDVLYWVNDAVGRD---------WPWIYFVTLIIIGSFFVLNLVLGVL 404 +++F + +GW D++Y DAVG D W +YF++ ++I +FFVLN+ +GV+ Sbjct: 1454 MSLFVLASKDGWVDIMYDGLDAVGVDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVV 1513 Query: 405 SGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNM 464 +F K R+ Q+ E E +E++ R Sbjct: 1514 VE-------------NFHKCRQHQE--------------------EEEARRREEKRLR-- 1538 Query: 465 SMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSN 524 RL + K++ Y+ ++RF R S+ Sbjct: 1539 ---------------------------RLEKKRRKAQCKPYYSDYSRF-RLLVHHLCTSH 1570 Query: 525 VFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYF 584 + ++ LN +T+A EHY QP L E N +F E + K+ + G + +F Sbjct: 1571 YLDLFITGVIGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFF 1630 Query: 585 VSLFNRFDCFVVCGGILETILVETKI-----MSPLGISVLRCVRLLRIFKITRYWNSLSN 639 +N+ D +V I+ L E ++ ++P I ++R +R+ R+ K+ + + Sbjct: 1631 QDRWNQLDLAIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRA 1690 Query: 640 LVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQT-----RRSTFDNFPQ 694 L+ +++ ++ + +L LL L IF+ LG++LF G DE R +TF NF Sbjct: 1691 LLDTVMQALPQVGNLGLLFMLLFFIFAALGVELF-GDLECDETHPCEGLGRHATFRNFGM 1749 Query: 695 SLLTVFQILTGEDWNSVMYDGIMAYGGPS--FPGMLVCIYFIILFICGNYILLNVFLAIA 752 + LT+F++ TG++WN +M D + S + ++ IYF+ + ++L+NV +A+ Sbjct: 1750 AFLTLFRVSTGDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVL 1809 Query: 753 VDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQEL 790 + +L ES A++E E E E + +T SP+ L Sbjct: 1810 MKHL--EESNKEAKEEAELEAELELEMKTLSPQPHSPL 1845 Score = 148 bits (374), Expect = 5e-35 Identities = 104/361 (28%), Positives = 166/361 (45%), Gaps = 65/361 (18%) Query: 114 RRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSN-LERVEYLFLIIFTV 172 R C+ V FE I +L I NCV L ++ P + ++ L+ + F V Sbjct: 71 RSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAFDDFIFAFFAV 130 Query: 173 EAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFD 232 E +K++A G+ F YL + WN LDF IV+ G+ L+ + Sbjct: 131 EMVVKMVALGI-FGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVS-------------- 175 Query: 233 VKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMG 292 A+R RVLRPLR ++ VPS+++++ ++ + L ++ LL FV I+ I+G++L+ G Sbjct: 176 FSAVRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAG 235 Query: 293 KMHKTCYNQEG-----------------------IADVPAEDDPSPCAL------ETGHG 323 + C+ E I P E+ C + G G Sbjct: 236 LLRNRCFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGG 295 Query: 324 RQC-------------------QNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEG 364 C Q T C G P G NFDN +A + +FQ IT+EG Sbjct: 296 PPCGLDYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEG 355 Query: 365 WTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKL 424 W D++Y+V DA + +IYF+ LII+GSFF++NL L V++ +FS+ +++ Q++ Sbjct: 356 WVDIMYFVMDA-HSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRV 414 Query: 425 R 425 R Sbjct: 415 R 415 Score = 147 bits (370), Expect = 1e-34 Identities = 111/377 (29%), Positives = 182/377 (48%), Gaps = 34/377 (9%) Query: 455 GMDEEKPRNMSMPTSETESVN--TENVAGGDIEGENCGAR--LAHRISKSKFSRYWRRWN 510 G E + + MP S++E+V T++ D+ + + L S +WR Sbjct: 674 GAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDAEPSSVLAFWRL-- 731 Query: 511 RFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAE 570 C R V S F ++ + +NTL++ E++ QP LT + +N +LF E Sbjct: 732 -ICDT-FRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNIVFTSLFALE 789 Query: 571 MLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKI 630 MLLK+ G Y + +N FD +V + E + + G+SVLR RL+R+ K+ Sbjct: 790 MLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGG-----GLSVLRTFRLMRVLKL 844 Query: 631 TRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFD---EMQTRRS 687 R+ +L + L+ ++ ++A+ +LL LFI IFS+LGM LFG KF + + R Sbjct: 845 VRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTLPDRK 904 Query: 688 TFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNV 747 FD+ +++TVFQILT EDWN V+Y+G+ + +YFI L GNY+L N+ Sbjct: 905 NFDSLLWAIVTVFQILTQEDWNKVLYNGMAS------TSSWAALYFIALMTFGNYVLFNL 958 Query: 748 FLAIAVDNLADAESLTSAQKEE-------EEEKERKKLARTAS----PEKKQELVEKPAV 796 +AI V+ ++ E + + +RKK S PE ++ L+ P + Sbjct: 959 LVAILVEGFQAEGDANKSESEPDFFSPSLDGDGDRKKCLALVSLGEHPELRKSLL-PPLI 1017 Query: 797 GESKEEKIELKSITADG 813 + + L T+ G Sbjct: 1018 IHTAATPMSLPKSTSTG 1034 Score = 112 bits (281), Expect = 3e-24 Identities = 95/369 (25%), Positives = 165/369 (44%), Gaps = 74/369 (20%) Query: 870 KAVPMPEAS--AFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHT- 926 + +P P + FF S ++R R C R V + F + + ILL+ ++L P + Sbjct: 49 EGLPYPALAPVVFFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIA 108 Query: 927 --SFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISF 984 S R IL FD F +E+ +KM A G F K + + +N LD +V ++ + Sbjct: 109 CDSQRCRILQAFDDFIFAFFAVEMVVKMVALGIF-GKKCYLGDTWNRLDFFIVIAGMLEY 167 Query: 985 GIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFA 1044 + ++ + R +RVLRPLRAINR ++ +V + + +GN++++ + F+F Sbjct: 168 SLDLQNVSFSAV-RTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFG 226 Query: 1045 CIGVQLFKGKL----YTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPR----------- 1089 +GVQL+ G L + + S + + Y T + E QPR Sbjct: 227 IVGVQLWAGLLRNRCFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVP 286 Query: 1090 ----------------------------SW----------ENSKF----DFDNVLAAMMA 1107 +W E++ F +FDN+ A +A Sbjct: 287 TLRGDGGGGPPCGLDYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIA 346 Query: 1108 LFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIV 1167 +F V T EGW +++Y +D+H+ YN+ I+FI+ II+ +FFM+N+ + + Sbjct: 347 IFQVITLEGWVDIMYFVMDAHS-----FYNF-----IYFILLIIVGSFFMINLCLVVIAT 396 Query: 1168 TFQEQGEQE 1176 F E ++E Sbjct: 397 QFSETKQRE 405 Score = 105 bits (261), Expect = 6e-22 Identities = 84/302 (27%), Positives = 140/302 (46%), Gaps = 62/302 (20%) Query: 120 IVEWKPFEIIILLTIFANCVALAI-YIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKV 178 IV+ K F I++ I N +++ I Y PE+ +NA LE +F +F +E LK+ Sbjct: 739 IVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNA----LEISNIVFTSLFALEMLLKL 794 Query: 179 IAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRA 238 + YG P Y++N +N+ D +IVV+ ++ + G +G G V LR Sbjct: 795 LVYG----PFGYIKNPYNIFDGVIVVISVWEIV-------------GQQGGGLSV--LRT 835 Query: 239 FRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTC 298 FR++R L+LV +P+LQ L ++K M + +L++ I I++I+G+ LF K Sbjct: 836 FRLMRVLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFAS-- 893 Query: 299 YNQEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQ 358 + D P NFD+ +A++TVFQ Sbjct: 894 ---------ERDGDTLP--------------------------DRKNFDSLLWAIVTVFQ 918 Query: 359 CITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKAR 418 +T E W VLY A W +YF+ L+ G++ + NL++ +L F E + K+ Sbjct: 919 ILTQEDWNKVLY-NGMASTSSWAALYFIALMTFGNYVLFNLLVAILVEGFQAEGDANKSE 977 Query: 419 GD 420 + Sbjct: 978 SE 979 Score = 104 bits (260), Expect = 8e-22 Identities = 70/267 (26%), Positives = 132/267 (49%), Gaps = 40/267 (14%) Query: 1215 VVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFK 1274 +V+S YF + + IL+NT+ + ++++ Q A+ I N++FT LF +EM+LKL+ + Sbjct: 739 IVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNIVFTSLFALEMLLKLLVYG 798 Query: 1275 PKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVM 1334 P Y + +N FD +IVV S+ +I ++ +S+ R FR+M Sbjct: 799 PFGYIKNPYNIFDGVIVVISVWEIV-----------------GQQGGGLSV--LRTFRLM 839 Query: 1335 RLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFG-KIAL-NDTTE 1392 R++KL+ ++ L +K+ + +L+++ FI++++GM +FG K A D Sbjct: 840 RVLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDT 899 Query: 1393 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA 1452 + NF + A++ +F+ T E W ++ M SS+A Sbjct: 900 LPDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMAST-------------------SSWA 940 Query: 1453 VFYFISFYMLCAFLIINLFVAVIMDNF 1479 YFI+ +++ NL VA++++ F Sbjct: 941 ALYFIALMTFGNYVLFNLLVAILVEGF 967 Score = 89.0 bits (219), Expect = 5e-17 Identities = 102/442 (23%), Positives = 191/442 (43%), Gaps = 76/442 (17%) Query: 763 TSAQKEEEEEKERKKLARTASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKIN 822 TS E +EK ++A ++ P L P S + +E +S G + KI+ Sbjct: 595 TSPPPETLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQST---GACQSSCKIS 651 Query: 823 MDDLQPNENE---DKSPYPNPETTGEEDEEEPEMPVGP-----------RPRPLSELHLK 868 L+ + D PY GE + + EMP + L + H + Sbjct: 652 SPCLKADSGACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSR 711 Query: 869 EKAVPMPEASAFFIFSSNNRFRLQC---HRIVNDTIFTNLILFFILLSSISLAAEDPVQH 925 + P+A + + +RL C +IV+ F I+ IL++++S+ E Q Sbjct: 712 RQRSLGPDAEPSSVLAF---WRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQP 768 Query: 926 TSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISF- 984 N L +IVFT++F +E+ LK+ YG F + +N +NI D ++V +S+ Sbjct: 769 EELTN-ALEISNIVFTSLFALEMLLKLLVYGPF----GYIKNPYNIFDGVIVVISVWEIV 823 Query: 985 GIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQ---F 1041 G Q ++V++ R++RVL+ +R L + + + V ++T+ N+ LL F Sbjct: 824 GQQGGGLSVLRTFRLMRVLKLVRF------LPALQRQLVVLMKTMDNVATFCMLLMLFIF 877 Query: 1042 MFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNV 1101 +F+ +G+ LF CK + + +DG+ + +FD++ Sbjct: 878 IFSILGMHLF----------------GCK--FASERDGDT----------LPDRKNFDSL 909 Query: 1102 LAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIF 1161 L A++ +F + T E W ++LY + S + +++FI + + + N+ Sbjct: 910 LWAIVTVFQILTQEDWNKVLYNGMASTSS----------WAALYFIALMTFGNYVLFNLL 959 Query: 1162 VGFVIVTFQEQGEQEYKNCELD 1183 V ++ FQ +G+ E D Sbjct: 960 VAILVEGFQAEGDANKSESEPD 981 Score = 63.9 bits (154), Expect = 2e-09 Identities = 47/169 (27%), Positives = 82/169 (48%), Gaps = 11/169 (6%) Query: 514 RRKCRAAVKSNVFYWLVIFLVFLNTLTIAS----EHYNQPNWLTEVQDTANKALLALFTA 569 R C V + F + + ++ LN +T+ E + + + + A F Sbjct: 71 RSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAFDDFIFAFFAV 130 Query: 570 EMLLKMYSLGL---QAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLR 626 EM++KM +LG+ + Y +NR D F+V G+LE L + + S +R VR+LR Sbjct: 131 EMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLD----LQNVSFSAVRTVRVLR 186 Query: 627 IFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGG 675 + S+ LV LL+++ + ++LLL F IF ++G+QL+ G Sbjct: 187 PLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAG 235 Score = 61.6 bits (148), Expect = 8e-09 Identities = 47/183 (25%), Positives = 83/183 (45%), Gaps = 31/183 (16%) Query: 1216 VNSTYFEYLMFVLILLNTICLAMQHY-------GQSCLFKIAMNILNMLFTGLFTVEMIL 1268 V + +FE + ++ILLN + L M Q C A + F F VEM++ Sbjct: 78 VCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAFDDFIFAF---FAVEMVV 134 Query: 1269 KLIA---FKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISI 1325 K++A F K Y D WN D IV+ +++ ++ N +S Sbjct: 135 KMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQN------------------VSF 176 Query: 1326 TFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKI 1385 + R RV+R ++ ++R +R L+ + + L V LL +FFI+ ++G+Q++ + Sbjct: 177 SAVRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGL 236 Query: 1386 ALN 1388 N Sbjct: 237 LRN 239 Score = 46.2 bits (108), Expect = 3e-04 Identities = 25/95 (26%), Positives = 47/95 (49%), Gaps = 6/95 (6%) Query: 689 FDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVF 748 FDN + + +FQ++T E W +MY + A+ +F IYFI+L I G++ ++N+ Sbjct: 337 FDNIGYAWIAIFQVITLEGWVDIMYFVMDAHSFYNF------IYFILLIIVGSFFMINLC 390 Query: 749 LAIAVDNLADAESLTSAQKEEEEEKERKKLARTAS 783 L + ++ + S E+ + + AS Sbjct: 391 LVVIATQFSETKQRESQLMREQRVRFLSNASTLAS 425 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.322 0.137 0.409 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 82,131,244 Number of Sequences: 37866 Number of extensions: 3964056 Number of successful extensions: 25870 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 122 Number of HSP's successfully gapped in prelim test: 266 Number of HSP's that attempted gapping in prelim test: 19236 Number of HSP's gapped (non-prelim): 2878 length of query: 2138 length of database: 18,247,518 effective HSP length: 118 effective length of query: 2020 effective length of database: 13,779,330 effective search space: 27834246600 effective search space used: 27834246600 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.