Search of human proteins with 24797097

Search of human proteins with 24797097

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|24797097 pyrroline-5-carboxylate reductase 1 isoform 1 [Homo
sapiens]
         (319 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|24797097 pyrroline-5-carboxylate reductase 1 isoform 1 [Homo ...   617   e-177
gi|24797095 pyrroline-5-carboxylate reductase 1 isoform 2 [Homo ...   563   e-161
gi|21361454 pyrroline-5-carboxylate reductase family, member 2 [...   528   e-150
gi|198041662 pyrroline-5-carboxylate reductase-like [Homo sapiens]    227   9e-60
gi|164698426 hypothetical protein LOC122945 isoform 1 [Homo sapi...    52   7e-07
gi|20302040 hypothetical protein LOC122945 isoform 2 [Homo sapiens]    52   7e-07
gi|76880486 activating signal cointegrator 1 complex subunit 3 i...    30   2.2  
gi|156627571 sorbitol dehydrogenase [Homo sapiens]                     30   3.7  
gi|54607135 translocase of outer mitochondrial membrane 70 homol...    30   3.7  
gi|118402590 myosin XV [Homo sapiens]                                  29   4.9  
gi|14719400 ADP-ribosylation factor binding protein 3 isoform sh...    29   4.9  
gi|20336267 ADP-ribosylation factor binding protein 3 isoform lo...    29   4.9  
gi|153791707 sorting nexin family member 30 [Homo sapiens]             29   6.3  
gi|134152667 ICBP90 binding protein 1 [Homo sapiens]                   28   8.3  

>gi|24797097 pyrroline-5-carboxylate reductase 1 isoform 1 [Homo
           sapiens]
          Length = 319

 Score =  617 bits (1591), Expect = e-177
 Identities = 319/319 (100%), Positives = 319/319 (100%)

Query: 1   MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETV 60
           MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETV
Sbjct: 1   MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETV 60

Query: 61  QHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRC 120
           QHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRC
Sbjct: 61  QHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRC 120

Query: 121 MTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAY 180
           MTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAY
Sbjct: 121 MTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAY 180

Query: 181 AFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIH 240
           AFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIH
Sbjct: 181 AFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIH 240

Query: 241 ALHVLESGGFRSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILDKVKLDSPAGTAL 300
           ALHVLESGGFRSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILDKVKLDSPAGTAL
Sbjct: 241 ALHVLESGGFRSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILDKVKLDSPAGTAL 300

Query: 301 SPSGHTKLLPRSLAPAGKD 319
           SPSGHTKLLPRSLAPAGKD
Sbjct: 301 SPSGHTKLLPRSLAPAGKD 319


>gi|24797095 pyrroline-5-carboxylate reductase 1 isoform 2 [Homo
           sapiens]
          Length = 316

 Score =  563 bits (1451), Expect = e-161
 Identities = 300/317 (94%), Positives = 300/317 (94%), Gaps = 4/317 (1%)

Query: 1   MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETV 60
           MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETV
Sbjct: 1   MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETV 60

Query: 61  QHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRC 120
           QHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRC
Sbjct: 61  QHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRC 120

Query: 121 MTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAY 180
           MTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAY
Sbjct: 121 MTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAY 180

Query: 181 AFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIH 240
           AFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIH
Sbjct: 181 AFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIH 240

Query: 241 ALHVLESGGFRSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILDKVKLDSPAGTAL 300
           ALHVLESGGFRSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILDK  L    G   
Sbjct: 241 ALHVLESGGFRSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILDKDHLPLELG--- 297

Query: 301 SPSG-HTKLLPRSLAPA 316
           SP G H  LL   LA A
Sbjct: 298 SPEGLHPLLLQYQLARA 314


>gi|21361454 pyrroline-5-carboxylate reductase family, member 2
           [Homo sapiens]
          Length = 320

 Score =  528 bits (1361), Expect = e-150
 Identities = 270/318 (84%), Positives = 297/318 (93%)

Query: 1   MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETV 60
           MSVGFIGAGQLA+ALA+GFTAAG+L+AHKI+ASSP+M+L TVSALRKMGV LT  NKETV
Sbjct: 1   MSVGFIGAGQLAYALARGFTAAGILSAHKIIASSPEMNLPTVSALRKMGVNLTRSNKETV 60

Query: 61  QHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRC 120
           +HSDVLFLAVKPHIIPFILDEIGAD++ RHIVVSCAAGVTISS+EKKL AF+PAP+VIRC
Sbjct: 61  KHSDVLFLAVKPHIIPFILDEIGADVQARHIVVSCAAGVTISSVEKKLMAFQPAPKVIRC 120

Query: 121 MTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAY 180
           MTNTPVVV+EGATVYATGTHA VEDG+L+EQL+SSVGFCTEVEEDLIDAVTGLSGSGPAY
Sbjct: 121 MTNTPVVVQEGATVYATGTHALVEDGQLLEQLMSSVGFCTEVEEDLIDAVTGLSGSGPAY 180

Query: 181 AFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIH 240
           AF ALDALADGGVKMGLPRRLA++LGAQALLGAAKMLL SEQHP QLKDNV SPGGATIH
Sbjct: 181 AFMALDALADGGVKMGLPRRLAIQLGAQALLGAAKMLLDSEQHPCQLKDNVCSPGGATIH 240

Query: 241 ALHVLESGGFRSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILDKVKLDSPAGTAL 300
           ALH LESGGFRSLLINAVEASCIRTRELQSMADQE++SPAA+KKT+LD+VKL+SP  + L
Sbjct: 241 ALHFLESGGFRSLLINAVEASCIRTRELQSMADQEKISPAALKKTLLDRVKLESPTVSTL 300

Query: 301 SPSGHTKLLPRSLAPAGK 318
           +PS   KLL RSLA  GK
Sbjct: 301 TPSSPGKLLTRSLALGGK 318


>gi|198041662 pyrroline-5-carboxylate reductase-like [Homo sapiens]
          Length = 286

 Score =  227 bits (579), Expect = 9e-60
 Identities = 124/267 (46%), Positives = 172/267 (64%), Gaps = 7/267 (2%)

Query: 3   VGFIGAGQLAFALAKGFTAAGVLAAHKIMASSP-DMDLATVSALRKMGVKLTPHNKETVQ 61
           VGF+GAG++A A+A+G   AG + A  I+AS+P D +L    AL   G + T  N+E +Q
Sbjct: 23  VGFVGAGRMAGAIAQGLIRAGKVEAQHILASAPTDRNLCHFQAL---GCRTTHSNQEVLQ 79

Query: 62  HSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRCM 121
              ++  A KPH++P +L E+   +   HI+VS AAGV++S++E+ L    P  RV+R +
Sbjct: 80  SCLLVIFATKPHVLPAVLAEVAPVVTTEHILVSVAAGVSLSTLEELLP---PNTRVLRVL 136

Query: 122 TNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAYA 181
            N P VV+EGA V A G H    + +L++ LL + G C EV E  +D  TGLSGSG A+ 
Sbjct: 137 PNLPCVVQEGAIVMARGRHVGSSETKLLQHLLEACGRCEEVPEAYVDIHTGLSGSGVAFV 196

Query: 182 FTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIHA 241
               +ALA+G VKMG+P  LA R+ AQ LLG AKMLLH  QHP QL+ +V +PGG TI+ 
Sbjct: 197 CAFSEALAEGAVKMGMPSSLAHRIAAQTLLGTAKMLLHEGQHPAQLRSDVCTPGGTTIYG 256

Query: 242 LHVLESGGFRSLLINAVEASCIRTREL 268
           LH LE GG R+  ++AVEA+  R +EL
Sbjct: 257 LHALEQGGLRAATMSAVEAATCRAKEL 283


>gi|164698426 hypothetical protein LOC122945 isoform 1 [Homo
           sapiens]
          Length = 359

 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 34/107 (31%), Positives = 52/107 (48%), Gaps = 2/107 (1%)

Query: 3   VGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETVQH 62
           VG IG G L   LA      G + A  +  S+   +  T+  L+K+G+K   HN + V  
Sbjct: 79  VGIIGGGHLGKQLAGTLLQLGPIPAESLRISTRRPE--TLGELQKLGIKCFYHNADLVSW 136

Query: 63  SDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLS 109
           +DV+FL   P  +P I  EI   +E   IV S  A + +  ++  L+
Sbjct: 137 ADVIFLCCLPSQLPNICVEIYTSLEKASIVYSFVAAIPLPRLKLLLN 183


>gi|20302040 hypothetical protein LOC122945 isoform 2 [Homo sapiens]
          Length = 250

 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 34/107 (31%), Positives = 52/107 (48%), Gaps = 2/107 (1%)

Query: 3   VGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETVQH 62
           VG IG G L   LA      G + A  +  S+   +  T+  L+K+G+K   HN + V  
Sbjct: 79  VGIIGGGHLGKQLAGTLLQLGPIPAESLRISTRRPE--TLGELQKLGIKCFYHNADLVSW 136

Query: 63  SDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLS 109
           +DV+FL   P  +P I  EI   +E   IV S  A + +  ++  L+
Sbjct: 137 ADVIFLCCLPSQLPNICVEIYTSLEKASIVYSFVAAIPLPRLKLLLN 183


>gi|76880486 activating signal cointegrator 1 complex subunit 3
           isoform a [Homo sapiens]
          Length = 2202

 Score = 30.4 bits (67), Expect = 2.2
 Identities = 22/77 (28%), Positives = 32/77 (41%)

Query: 36  DMDLATVSALRKMGVKLTPHNKETVQHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSC 95
           DM L+    LR   +  TP   + V    V  +A+   +   ILDE+    EDR  V+  
Sbjct: 567 DMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVRLLILDEVHLLHEDRGPVLES 626

Query: 96  AAGVTISSIEKKLSAFR 112
               T+  +E   S  R
Sbjct: 627 IVARTLRQVESTQSMIR 643


>gi|156627571 sorbitol dehydrogenase [Homo sapiens]
          Length = 357

 Score = 29.6 bits (65), Expect = 3.7
 Identities = 32/136 (23%), Positives = 51/136 (37%), Gaps = 7/136 (5%)

Query: 107 KLSAFRPAPRVIRCMTNTP------VVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCT 160
           K+  +  +P +  C T               A  Y    +   E+G L+E L   +  C 
Sbjct: 107 KMGRYNLSPSIFFCATPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACR 166

Query: 161 EVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHS 220
                L   V  + G+GP    T L A A G  ++ +    A RL     +GA  +L  S
Sbjct: 167 RGGVTLGHKVL-VCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQIS 225

Query: 221 EQHPGQLKDNVSSPGG 236
           ++ P ++   V    G
Sbjct: 226 KESPQEIARKVEGQLG 241


>gi|54607135 translocase of outer mitochondrial membrane 70 homolog
           A [Homo sapiens]
          Length = 608

 Score = 29.6 bits (65), Expect = 3.7
 Identities = 25/62 (40%), Positives = 31/62 (50%), Gaps = 7/62 (11%)

Query: 162 VEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPR-RLAVRLGAQALLGAAKMLLHS 220
           VE  ++ A    SGSG     TA      G    GLPR +LA+ +GA  LLGA  + L S
Sbjct: 7   VEAAVVAAAVPSSGSGVGGGGTA------GPGTGGLPRWQLALAVGAPLLLGAGAIYLWS 60

Query: 221 EQ 222
            Q
Sbjct: 61  RQ 62


>gi|118402590 myosin XV [Homo sapiens]
          Length = 3530

 Score = 29.3 bits (64), Expect = 4.9
 Identities = 13/31 (41%), Positives = 21/31 (67%)

Query: 260  ASCIRTRELQSMADQEQVSPAAIKKTILDKV 290
            AS +  RE+Q++A+  Q+SP  ++K I  KV
Sbjct: 1501 ASVVSAREIQAVAELLQISPEGLQKAITFKV 1531


>gi|14719400 ADP-ribosylation factor binding protein 3 isoform short
           [Homo sapiens]
          Length = 690

 Score = 29.3 bits (64), Expect = 4.9
 Identities = 21/64 (32%), Positives = 27/64 (42%), Gaps = 7/64 (10%)

Query: 246 ESGGFRSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILD-------KVKLDSPAGT 298
           +  GFR L   A E    R   L  +      +P  +K  +L        KVKL  P+GT
Sbjct: 570 DKNGFRILFHFAKECPPGRPDVLVVVVSMLNTAPLPVKSIVLQAAVPKSMKVKLQPPSGT 629

Query: 299 ALSP 302
            LSP
Sbjct: 630 ELSP 633


>gi|20336267 ADP-ribosylation factor binding protein 3 isoform long
           [Homo sapiens]
          Length = 723

 Score = 29.3 bits (64), Expect = 4.9
 Identities = 21/64 (32%), Positives = 27/64 (42%), Gaps = 7/64 (10%)

Query: 246 ESGGFRSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILD-------KVKLDSPAGT 298
           +  GFR L   A E    R   L  +      +P  +K  +L        KVKL  P+GT
Sbjct: 603 DKNGFRILFHFAKECPPGRPDVLVVVVSMLNTAPLPVKSIVLQAAVPKSMKVKLQPPSGT 662

Query: 299 ALSP 302
            LSP
Sbjct: 663 ELSP 666


>gi|153791707 sorting nexin family member 30 [Homo sapiens]
          Length = 437

 Score = 28.9 bits (63), Expect = 6.3
 Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 1/77 (1%)

Query: 96  AAGVTISSIEKKLSAF-RPAPRVIRCMTNTPVVVREGATVYATGTHAQVEDGRLMEQLLS 154
           A G  + +   KL    R A R+I+      V +RE   VY+T +  + E    +E + +
Sbjct: 244 AIGDYLDTFALKLGTIDRIAQRIIKEEIEYLVELREYGPVYSTWSALEGELAEPLEGVSA 303

Query: 155 SVGFCTEVEEDLIDAVT 171
            +G C+   E+L D +T
Sbjct: 304 CIGNCSTALEELTDDMT 320


>gi|134152667 ICBP90 binding protein 1 [Homo sapiens]
          Length = 1440

 Score = 28.5 bits (62), Expect = 8.3
 Identities = 40/160 (25%), Positives = 64/160 (40%), Gaps = 27/160 (16%)

Query: 150 EQLLSSVGFCTEVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQA 209
           E  L S+   TEV E L +  +G+   GP    T L+ +AD  + +  P  + VRL    
Sbjct: 778 EHDLKSLSGLTEVMEILKEGSSGMDNKGP---LTELEDVADVHMLVHSPAHVRVRLDHYQ 834

Query: 210 LLGAAKMLLHSEQHPGQLKDNVSSPGGATIH----ALHVL-------------------E 246
            L   ++    ++   QL  +  S  G+ +      + VL                   +
Sbjct: 835 YLALLRLKEVLQRLQEQLTKDTESMTGSPLQNQTACIGVLFPSAEVALLMHPAPGAVDAD 894

Query: 247 SGGFRSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTI 286
           S G  S  +   E S    REL+S A  +Q  PA+ +K +
Sbjct: 895 SAGSDSTSLVDSELSPSEDRELKSDASSDQ-GPASPEKVL 933


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.373 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,615,334
Number of Sequences: 37866
Number of extensions: 504860
Number of successful extensions: 1082
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1071
Number of HSP's gapped (non-prelim): 14
length of query: 319
length of database: 18,247,518
effective HSP length: 102
effective length of query: 217
effective length of database: 14,385,186
effective search space: 3121585362
effective search space used: 3121585362
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.