BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [Homo sapiens] (1042 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [... 2078 0.0 gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 ... 2014 0.0 gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [H... 1973 0.0 gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [... 1689 0.0 gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [... 1689 0.0 gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 1556 0.0 gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 1556 0.0 gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Hom... 1556 0.0 gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Hom... 1556 0.0 gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Hom... 1556 0.0 gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Hom... 1555 0.0 gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Hom... 1555 0.0 gi|239751049 PREDICTED: similar to ATPase, Ca++ transporting, fa... 996 0.0 gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sap... 478 e-134 gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sap... 478 e-134 gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sap... 478 e-134 gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sap... 468 e-131 gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo ... 443 e-124 gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapi... 372 e-103 gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens] 371 e-102 gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens] 370 e-102 gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens] 363 e-100 gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapi... 357 3e-98 gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapi... 357 3e-98 gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens] 357 3e-98 gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens] 338 2e-92 gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sap... 303 6e-82 gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sa... 295 2e-79 gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sa... 295 2e-79 gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sa... 289 8e-78 >gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [Homo sapiens] Length = 1042 Score = 2078 bits (5385), Expect = 0.0 Identities = 1042/1042 (100%), Positives = 1042/1042 (100%) Query: 1 MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL Sbjct: 1 MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 Query: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK Sbjct: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 Query: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL 180 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL Sbjct: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL 180 Query: 181 TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 240 TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV Sbjct: 181 TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 240 Query: 241 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 300 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV Sbjct: 241 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 300 Query: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 Query: 361 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 420 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC Sbjct: 361 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 420 Query: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK 480 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK 480 Query: 481 KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGV 540 KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGV Sbjct: 481 KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGV 540 Query: 541 KQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLD 600 KQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLD Sbjct: 541 KQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLD 600 Query: 601 PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDEL 660 PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDEL Sbjct: 601 PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDEL 660 Query: 661 NPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG 720 NPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG Sbjct: 661 NPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG 720 Query: 721 SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL 780 SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL Sbjct: 721 SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL 780 Query: 781 GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG 840 GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG Sbjct: 781 GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG 840 Query: 841 CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMAL 900 CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMAL Sbjct: 841 CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMAL 900 Query: 901 SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP 960 SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP Sbjct: 901 SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP 960 Query: 961 LNVTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQPATKSCSFSACTDGISWPFVL 1020 LNVTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQPATKSCSFSACTDGISWPFVL Sbjct: 961 LNVTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQPATKSCSFSACTDGISWPFVL 1020 Query: 1021 LIMPLVIWVYSTDTNFSDMFWS 1042 LIMPLVIWVYSTDTNFSDMFWS Sbjct: 1021 LIMPLVIWVYSTDTNFSDMFWS 1042 >gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 [Homo sapiens] Length = 1015 Score = 2014 bits (5219), Expect = 0.0 Identities = 1015/1042 (97%), Positives = 1015/1042 (97%), Gaps = 27/1042 (2%) Query: 1 MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL Sbjct: 1 MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 Query: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK Sbjct: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 Query: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL 180 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIA Sbjct: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIA-------------------------- 154 Query: 181 TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 240 GESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV Sbjct: 155 -GESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 213 Query: 241 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 300 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV Sbjct: 214 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 273 Query: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ Sbjct: 274 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 333 Query: 361 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 420 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC Sbjct: 334 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 393 Query: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK 480 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK Sbjct: 394 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK 453 Query: 481 KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGV 540 KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGV Sbjct: 454 KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGV 513 Query: 541 KQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLD 600 KQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLD Sbjct: 514 KQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLD 573 Query: 601 PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDEL 660 PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDEL Sbjct: 574 PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDEL 633 Query: 661 NPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG 720 NPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG Sbjct: 634 NPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG 693 Query: 721 SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL 780 SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL Sbjct: 694 SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL 753 Query: 781 GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG 840 GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG Sbjct: 754 GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG 813 Query: 841 CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMAL 900 CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMAL Sbjct: 814 CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMAL 873 Query: 901 SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP 960 SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP Sbjct: 874 SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP 933 Query: 961 LNVTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQPATKSCSFSACTDGISWPFVL 1020 LNVTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQPATKSCSFSACTDGISWPFVL Sbjct: 934 LNVTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQPATKSCSFSACTDGISWPFVL 993 Query: 1021 LIMPLVIWVYSTDTNFSDMFWS 1042 LIMPLVIWVYSTDTNFSDMFWS Sbjct: 994 LIMPLVIWVYSTDTNFSDMFWS 1015 >gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [Homo sapiens] Length = 997 Score = 1973 bits (5111), Expect = 0.0 Identities = 993/993 (100%), Positives = 993/993 (100%) Query: 1 MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL Sbjct: 1 MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 Query: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK Sbjct: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 Query: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL 180 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL Sbjct: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL 180 Query: 181 TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 240 TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV Sbjct: 181 TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 240 Query: 241 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 300 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV Sbjct: 241 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 300 Query: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 Query: 361 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 420 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC Sbjct: 361 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 420 Query: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK 480 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK 480 Query: 481 KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGV 540 KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGV Sbjct: 481 KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGV 540 Query: 541 KQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLD 600 KQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLD Sbjct: 541 KQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLD 600 Query: 601 PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDEL 660 PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDEL Sbjct: 601 PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDEL 660 Query: 661 NPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG 720 NPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG Sbjct: 661 NPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG 720 Query: 721 SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL 780 SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL Sbjct: 721 SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL 780 Query: 781 GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG 840 GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG Sbjct: 781 GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG 840 Query: 841 CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMAL 900 CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMAL Sbjct: 841 CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMAL 900 Query: 901 SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP 960 SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP Sbjct: 901 SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP 960 Query: 961 LNVTQWLMVLKISLPVILMDETLKFVARNYLEP 993 LNVTQWLMVLKISLPVILMDETLKFVARNYLEP Sbjct: 961 LNVTQWLMVLKISLPVILMDETLKFVARNYLEP 993 >gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [Homo sapiens] Length = 994 Score = 1689 bits (4374), Expect = 0.0 Identities = 838/993 (84%), Positives = 925/993 (93%), Gaps = 1/993 (0%) Query: 1 MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 ME AH KT EE L +FGV+E+TGL+ +QVK+ E++G NELPAEEGKTL ELVIEQFEDL Sbjct: 1 MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL 60 Query: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLIL+ANAIVGVWQERNAENAIEALK Sbjct: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 120 Query: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL 180 EYEPEMGKVYR DRKSVQRIKA+DIVPGDIVE+AVGDKVPADIR+ +IKSTTLRVDQSIL Sbjct: 121 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 180 Query: 181 TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 240 TGESVSVIKHT+PVPDPRAVNQDKKNMLFSGTNIAAGKA+G+V TGV TEIGKIRD+M Sbjct: 181 TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA 240 Query: 241 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 300 ATEQ++TPLQQKLDEFGEQLSKVISLIC+AVW+INIGHFNDPVHGGSW RGAIYYFKIAV Sbjct: 241 ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV 300 Query: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 Query: 361 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 420 MSVC+MFI+D+V+GD C LNEF+ITGSTYAP GEV K+DKPV QYDGLVELATICALC Sbjct: 361 MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC 420 Query: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK 480 NDS+LD+NEAKGVYEKVGEATETALT LVEKMNVF+T+++ LSK+ERANACNSVI+QLMK Sbjct: 421 NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK 480 Query: 481 KEFTLEFSRDRKSMSVYCTPNKPSRTSM-SKMFVKGAPEGVIDRCTHIRVGSTKVPMTSG 539 KEFTLEFSRDRKSMSVYC+P K SR ++ +KMFVKGAPEGVIDRC ++RVG+T+VP+T Sbjct: 481 KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP 540 Query: 540 VKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGML 599 VK+KIM+VI+EWG+G DTLRCLALAT D P +REEM L+DSA F++YET+LTFVG VGML Sbjct: 541 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGML 600 Query: 600 DPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDE 659 DPPR EV S++LCR AGIRVIMITGDNKGTA+AICRRIGIFG++E+V +A+TGREFD+ Sbjct: 601 DPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDD 660 Query: 660 LNPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAM 719 L + QR+AC A CFARVEPSHKSKIVE+LQS+DEITAMTGDGVNDAPALKKAEIGIAM Sbjct: 661 LPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAM 720 Query: 720 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 779 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA Sbjct: 721 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 780 Query: 780 LGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAI 839 LG PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM++PPR+PKEPLISGWLFFRY+AI Sbjct: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAI 840 Query: 840 GCYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMA 899 G YVGAATVGAAAWWF+ A+ GP V++ QL+HF+QC EDN FEG+DC +FE+P PMTMA Sbjct: 841 GGYVGAATVGAAAWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMA 900 Query: 900 LSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQIT 959 LSVLVTIEMCNALNSLSENQSLLRMPPW NIWL+GSICLSMSLHFLILYV+PLP+IF++ Sbjct: 901 LSVLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLR 960 Query: 960 PLNVTQWLMVLKISLPVILMDETLKFVARNYLE 992 L++TQWLMVLKISLPVI +DE LKFVARNYLE Sbjct: 961 ALDLTQWLMVLKISLPVIGLDEILKFVARNYLE 993 >gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [Homo sapiens] Length = 1001 Score = 1689 bits (4374), Expect = 0.0 Identities = 838/993 (84%), Positives = 925/993 (93%), Gaps = 1/993 (0%) Query: 1 MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 ME AH KT EE L +FGV+E+TGL+ +QVK+ E++G NELPAEEGKTL ELVIEQFEDL Sbjct: 1 MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL 60 Query: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLIL+ANAIVGVWQERNAENAIEALK Sbjct: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 120 Query: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL 180 EYEPEMGKVYR DRKSVQRIKA+DIVPGDIVE+AVGDKVPADIR+ +IKSTTLRVDQSIL Sbjct: 121 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 180 Query: 181 TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 240 TGESVSVIKHT+PVPDPRAVNQDKKNMLFSGTNIAAGKA+G+V TGV TEIGKIRD+M Sbjct: 181 TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA 240 Query: 241 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 300 ATEQ++TPLQQKLDEFGEQLSKVISLIC+AVW+INIGHFNDPVHGGSW RGAIYYFKIAV Sbjct: 241 ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV 300 Query: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 Query: 361 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 420 MSVC+MFI+D+V+GD C LNEF+ITGSTYAP GEV K+DKPV QYDGLVELATICALC Sbjct: 361 MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC 420 Query: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK 480 NDS+LD+NEAKGVYEKVGEATETALT LVEKMNVF+T+++ LSK+ERANACNSVI+QLMK Sbjct: 421 NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK 480 Query: 481 KEFTLEFSRDRKSMSVYCTPNKPSRTSM-SKMFVKGAPEGVIDRCTHIRVGSTKVPMTSG 539 KEFTLEFSRDRKSMSVYC+P K SR ++ +KMFVKGAPEGVIDRC ++RVG+T+VP+T Sbjct: 481 KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP 540 Query: 540 VKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGML 599 VK+KIM+VI+EWG+G DTLRCLALAT D P +REEM L+DSA F++YET+LTFVG VGML Sbjct: 541 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGML 600 Query: 600 DPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDE 659 DPPR EV S++LCR AGIRVIMITGDNKGTA+AICRRIGIFG++E+V +A+TGREFD+ Sbjct: 601 DPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDD 660 Query: 660 LNPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAM 719 L + QR+AC A CFARVEPSHKSKIVE+LQS+DEITAMTGDGVNDAPALKKAEIGIAM Sbjct: 661 LPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAM 720 Query: 720 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 779 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA Sbjct: 721 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 780 Query: 780 LGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAI 839 LG PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM++PPR+PKEPLISGWLFFRY+AI Sbjct: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAI 840 Query: 840 GCYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMA 899 G YVGAATVGAAAWWF+ A+ GP V++ QL+HF+QC EDN FEG+DC +FE+P PMTMA Sbjct: 841 GGYVGAATVGAAAWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMA 900 Query: 900 LSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQIT 959 LSVLVTIEMCNALNSLSENQSLLRMPPW NIWL+GSICLSMSLHFLILYV+PLP+IF++ Sbjct: 901 LSVLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLR 960 Query: 960 PLNVTQWLMVLKISLPVILMDETLKFVARNYLE 992 L++TQWLMVLKISLPVI +DE LKFVARNYLE Sbjct: 961 ALDLTQWLMVLKISLPVIGLDEILKFVARNYLE 993 >gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Homo sapiens] Length = 1029 Score = 1556 bits (4028), Expect = 0.0 Identities = 769/1001 (76%), Positives = 875/1001 (87%), Gaps = 4/1001 (0%) Query: 1 MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 ME AH +VL HF V GLS QV +ER+G NELP+EEGK+L ELV+EQFEDL Sbjct: 1 MEAAHLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDL 60 Query: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 LVRILLLAA +SFVLAWFEEGEET TAFVEP VI+LILVANAIVGVWQERNAE+AIEALK Sbjct: 61 LVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120 Query: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL 180 EYEPEMGKV R DRK VQRI+A+DIVPGDIVE+AVGDKVPAD+RL IKSTTLRVDQSIL Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180 Query: 181 TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 240 TGESVSV KHT+ +PDPRAVNQDKKNMLFSGTNI +GKA+GV VATG++TE+GKIR +M Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMA 240 Query: 241 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 300 A E ERTPLQ+KLDEFG QLS IS+IC+AVW+INIGHF DP HGGSW+RGA+YYFKIAV Sbjct: 241 AVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAV 300 Query: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 ALAVAAIPEGLPAVITTCLALGTRRMA+KNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 Query: 361 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 420 MSVCRMF++ + +C L+EFTI+G+TY P GEV + D+PV C Q+DGLVELATICALC Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420 Query: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK 480 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDT+L+ LS++ERA ACN+VIKQLM+ Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMR 480 Query: 481 KEFTLEFSRDRKSMSVYCTPNKPSRTSM-SKMFVKGAPEGVIDRCTHIRVGSTKVPMTSG 539 KEFTLEFSRDRKSMSVYCTP +P T SKMFVKGAPE VI+RC+ +RVGS P+T Sbjct: 481 KEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPT 540 Query: 540 VKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGML 599 +++I++ IR+WGSGSDTLRCLALAT D P R+E+M L+D + F++YET+LTFVGCVGML Sbjct: 541 SREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGML 600 Query: 600 DPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDE 659 DPPR EVA+ + C QAGIRV+MITGDNKGTAVAICRR+GIFG EDV KA+TGREFD+ Sbjct: 601 DPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREFDD 660 Query: 660 LNPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAM 719 L+P QR AC ARCFARVEP+HKS+IVE LQSF+EITAMTGDGVNDAPALKKAEIGIAM Sbjct: 661 LSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAM 720 Query: 720 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 779 GSGTAVAK+A+EMVL+DDNF++IVAAVEEGRAIY+NMKQFIRYLISSNVGEVVCIFLTA Sbjct: 721 GSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAI 780 Query: 780 LGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAI 839 LG PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM K PR+P+E LISGWLFFRYLAI Sbjct: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRYLAI 840 Query: 840 GCYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMA 899 G YVG ATV AA WWF+ GP ++FYQL +FL+C EDNP F G+DC +FES +P TMA Sbjct: 841 GVYVGLATVAAATWWFVYDAEGPHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMA 900 Query: 900 LSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQIT 959 LSVLVTIEMCNALNS+SENQSLLRMPPW N WL+ ++ +SM+LHFLIL V PLPLIFQ+T Sbjct: 901 LSVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVT 960 Query: 960 PLNVTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQP 1000 PL+ QW++VL+ISLPVIL+DE LK+++RN++ C+ P Sbjct: 961 PLSGRQWVVVLQISLPVILLDEALKYLSRNHMH---ACLYP 998 >gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Homo sapiens] Length = 1029 Score = 1556 bits (4028), Expect = 0.0 Identities = 769/1001 (76%), Positives = 875/1001 (87%), Gaps = 4/1001 (0%) Query: 1 MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 ME AH +VL HF V GLS QV +ER+G NELP+EEGK+L ELV+EQFEDL Sbjct: 1 MEAAHLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDL 60 Query: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 LVRILLLAA +SFVLAWFEEGEET TAFVEP VI+LILVANAIVGVWQERNAE+AIEALK Sbjct: 61 LVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120 Query: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL 180 EYEPEMGKV R DRK VQRI+A+DIVPGDIVE+AVGDKVPAD+RL IKSTTLRVDQSIL Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180 Query: 181 TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 240 TGESVSV KHT+ +PDPRAVNQDKKNMLFSGTNI +GKA+GV VATG++TE+GKIR +M Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMA 240 Query: 241 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 300 A E ERTPLQ+KLDEFG QLS IS+IC+AVW+INIGHF DP HGGSW+RGA+YYFKIAV Sbjct: 241 AVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAV 300 Query: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 ALAVAAIPEGLPAVITTCLALGTRRMA+KNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 Query: 361 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 420 MSVCRMF++ + +C L+EFTI+G+TY P GEV + D+PV C Q+DGLVELATICALC Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420 Query: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK 480 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDT+L+ LS++ERA ACN+VIKQLM+ Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMR 480 Query: 481 KEFTLEFSRDRKSMSVYCTPNKPSRTSM-SKMFVKGAPEGVIDRCTHIRVGSTKVPMTSG 539 KEFTLEFSRDRKSMSVYCTP +P T SKMFVKGAPE VI+RC+ +RVGS P+T Sbjct: 481 KEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPT 540 Query: 540 VKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGML 599 +++I++ IR+WGSGSDTLRCLALAT D P R+E+M L+D + F++YET+LTFVGCVGML Sbjct: 541 SREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGML 600 Query: 600 DPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDE 659 DPPR EVA+ + C QAGIRV+MITGDNKGTAVAICRR+GIFG EDV KA+TGREFD+ Sbjct: 601 DPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREFDD 660 Query: 660 LNPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAM 719 L+P QR AC ARCFARVEP+HKS+IVE LQSF+EITAMTGDGVNDAPALKKAEIGIAM Sbjct: 661 LSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAM 720 Query: 720 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 779 GSGTAVAK+A+EMVL+DDNF++IVAAVEEGRAIY+NMKQFIRYLISSNVGEVVCIFLTA Sbjct: 721 GSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAI 780 Query: 780 LGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAI 839 LG PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM K PR+P+E LISGWLFFRYLAI Sbjct: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRYLAI 840 Query: 840 GCYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMA 899 G YVG ATV AA WWF+ GP ++FYQL +FL+C EDNP F G+DC +FES +P TMA Sbjct: 841 GVYVGLATVAAATWWFVYDAEGPHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMA 900 Query: 900 LSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQIT 959 LSVLVTIEMCNALNS+SENQSLLRMPPW N WL+ ++ +SM+LHFLIL V PLPLIFQ+T Sbjct: 901 LSVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVT 960 Query: 960 PLNVTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQP 1000 PL+ QW++VL+ISLPVIL+DE LK+++RN++ C+ P Sbjct: 961 PLSGRQWVVVLQISLPVILLDEALKYLSRNHMH---ACLYP 998 >gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Homo sapiens] Length = 1043 Score = 1556 bits (4028), Expect = 0.0 Identities = 769/1001 (76%), Positives = 875/1001 (87%), Gaps = 4/1001 (0%) Query: 1 MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 ME AH +VL HF V GLS QV +ER+G NELP+EEGK+L ELV+EQFEDL Sbjct: 1 MEAAHLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDL 60 Query: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 LVRILLLAA +SFVLAWFEEGEET TAFVEP VI+LILVANAIVGVWQERNAE+AIEALK Sbjct: 61 LVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120 Query: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL 180 EYEPEMGKV R DRK VQRI+A+DIVPGDIVE+AVGDKVPAD+RL IKSTTLRVDQSIL Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180 Query: 181 TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 240 TGESVSV KHT+ +PDPRAVNQDKKNMLFSGTNI +GKA+GV VATG++TE+GKIR +M Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMA 240 Query: 241 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 300 A E ERTPLQ+KLDEFG QLS IS+IC+AVW+INIGHF DP HGGSW+RGA+YYFKIAV Sbjct: 241 AVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAV 300 Query: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 ALAVAAIPEGLPAVITTCLALGTRRMA+KNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 Query: 361 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 420 MSVCRMF++ + +C L+EFTI+G+TY P GEV + D+PV C Q+DGLVELATICALC Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420 Query: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK 480 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDT+L+ LS++ERA ACN+VIKQLM+ Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMR 480 Query: 481 KEFTLEFSRDRKSMSVYCTPNKPSRTSM-SKMFVKGAPEGVIDRCTHIRVGSTKVPMTSG 539 KEFTLEFSRDRKSMSVYCTP +P T SKMFVKGAPE VI+RC+ +RVGS P+T Sbjct: 481 KEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPT 540 Query: 540 VKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGML 599 +++I++ IR+WGSGSDTLRCLALAT D P R+E+M L+D + F++YET+LTFVGCVGML Sbjct: 541 SREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGML 600 Query: 600 DPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDE 659 DPPR EVA+ + C QAGIRV+MITGDNKGTAVAICRR+GIFG EDV KA+TGREFD+ Sbjct: 601 DPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREFDD 660 Query: 660 LNPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAM 719 L+P QR AC ARCFARVEP+HKS+IVE LQSF+EITAMTGDGVNDAPALKKAEIGIAM Sbjct: 661 LSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAM 720 Query: 720 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 779 GSGTAVAK+A+EMVL+DDNF++IVAAVEEGRAIY+NMKQFIRYLISSNVGEVVCIFLTA Sbjct: 721 GSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAI 780 Query: 780 LGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAI 839 LG PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM K PR+P+E LISGWLFFRYLAI Sbjct: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRYLAI 840 Query: 840 GCYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMA 899 G YVG ATV AA WWF+ GP ++FYQL +FL+C EDNP F G+DC +FES +P TMA Sbjct: 841 GVYVGLATVAAATWWFVYDAEGPHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMA 900 Query: 900 LSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQIT 959 LSVLVTIEMCNALNS+SENQSLLRMPPW N WL+ ++ +SM+LHFLIL V PLPLIFQ+T Sbjct: 901 LSVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVT 960 Query: 960 PLNVTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQP 1000 PL+ QW++VL+ISLPVIL+DE LK+++RN++ C+ P Sbjct: 961 PLSGRQWVVVLQISLPVILLDEALKYLSRNHMH---ACLYP 998 >gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Homo sapiens] Length = 1044 Score = 1556 bits (4028), Expect = 0.0 Identities = 769/1001 (76%), Positives = 875/1001 (87%), Gaps = 4/1001 (0%) Query: 1 MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 ME AH +VL HF V GLS QV +ER+G NELP+EEGK+L ELV+EQFEDL Sbjct: 1 MEAAHLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDL 60 Query: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 LVRILLLAA +SFVLAWFEEGEET TAFVEP VI+LILVANAIVGVWQERNAE+AIEALK Sbjct: 61 LVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120 Query: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL 180 EYEPEMGKV R DRK VQRI+A+DIVPGDIVE+AVGDKVPAD+RL IKSTTLRVDQSIL Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180 Query: 181 TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 240 TGESVSV KHT+ +PDPRAVNQDKKNMLFSGTNI +GKA+GV VATG++TE+GKIR +M Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMA 240 Query: 241 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 300 A E ERTPLQ+KLDEFG QLS IS+IC+AVW+INIGHF DP HGGSW+RGA+YYFKIAV Sbjct: 241 AVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAV 300 Query: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 ALAVAAIPEGLPAVITTCLALGTRRMA+KNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 Query: 361 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 420 MSVCRMF++ + +C L+EFTI+G+TY P GEV + D+PV C Q+DGLVELATICALC Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420 Query: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK 480 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDT+L+ LS++ERA ACN+VIKQLM+ Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMR 480 Query: 481 KEFTLEFSRDRKSMSVYCTPNKPSRTSM-SKMFVKGAPEGVIDRCTHIRVGSTKVPMTSG 539 KEFTLEFSRDRKSMSVYCTP +P T SKMFVKGAPE VI+RC+ +RVGS P+T Sbjct: 481 KEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPT 540 Query: 540 VKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGML 599 +++I++ IR+WGSGSDTLRCLALAT D P R+E+M L+D + F++YET+LTFVGCVGML Sbjct: 541 SREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGML 600 Query: 600 DPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDE 659 DPPR EVA+ + C QAGIRV+MITGDNKGTAVAICRR+GIFG EDV KA+TGREFD+ Sbjct: 601 DPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREFDD 660 Query: 660 LNPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAM 719 L+P QR AC ARCFARVEP+HKS+IVE LQSF+EITAMTGDGVNDAPALKKAEIGIAM Sbjct: 661 LSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAM 720 Query: 720 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 779 GSGTAVAK+A+EMVL+DDNF++IVAAVEEGRAIY+NMKQFIRYLISSNVGEVVCIFLTA Sbjct: 721 GSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAI 780 Query: 780 LGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAI 839 LG PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM K PR+P+E LISGWLFFRYLAI Sbjct: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRYLAI 840 Query: 840 GCYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMA 899 G YVG ATV AA WWF+ GP ++FYQL +FL+C EDNP F G+DC +FES +P TMA Sbjct: 841 GVYVGLATVAAATWWFVYDAEGPHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMA 900 Query: 900 LSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQIT 959 LSVLVTIEMCNALNS+SENQSLLRMPPW N WL+ ++ +SM+LHFLIL V PLPLIFQ+T Sbjct: 901 LSVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVT 960 Query: 960 PLNVTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQP 1000 PL+ QW++VL+ISLPVIL+DE LK+++RN++ C+ P Sbjct: 961 PLSGRQWVVVLQISLPVILLDEALKYLSRNHMH---ACLYP 998 >gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Homo sapiens] Length = 1052 Score = 1556 bits (4028), Expect = 0.0 Identities = 769/1001 (76%), Positives = 875/1001 (87%), Gaps = 4/1001 (0%) Query: 1 MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 ME AH +VL HF V GLS QV +ER+G NELP+EEGK+L ELV+EQFEDL Sbjct: 1 MEAAHLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDL 60 Query: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 LVRILLLAA +SFVLAWFEEGEET TAFVEP VI+LILVANAIVGVWQERNAE+AIEALK Sbjct: 61 LVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120 Query: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL 180 EYEPEMGKV R DRK VQRI+A+DIVPGDIVE+AVGDKVPAD+RL IKSTTLRVDQSIL Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180 Query: 181 TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 240 TGESVSV KHT+ +PDPRAVNQDKKNMLFSGTNI +GKA+GV VATG++TE+GKIR +M Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMA 240 Query: 241 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 300 A E ERTPLQ+KLDEFG QLS IS+IC+AVW+INIGHF DP HGGSW+RGA+YYFKIAV Sbjct: 241 AVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAV 300 Query: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 ALAVAAIPEGLPAVITTCLALGTRRMA+KNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 Query: 361 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 420 MSVCRMF++ + +C L+EFTI+G+TY P GEV + D+PV C Q+DGLVELATICALC Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420 Query: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK 480 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDT+L+ LS++ERA ACN+VIKQLM+ Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMR 480 Query: 481 KEFTLEFSRDRKSMSVYCTPNKPSRTSM-SKMFVKGAPEGVIDRCTHIRVGSTKVPMTSG 539 KEFTLEFSRDRKSMSVYCTP +P T SKMFVKGAPE VI+RC+ +RVGS P+T Sbjct: 481 KEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPT 540 Query: 540 VKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGML 599 +++I++ IR+WGSGSDTLRCLALAT D P R+E+M L+D + F++YET+LTFVGCVGML Sbjct: 541 SREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGML 600 Query: 600 DPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDE 659 DPPR EVA+ + C QAGIRV+MITGDNKGTAVAICRR+GIFG EDV KA+TGREFD+ Sbjct: 601 DPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREFDD 660 Query: 660 LNPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAM 719 L+P QR AC ARCFARVEP+HKS+IVE LQSF+EITAMTGDGVNDAPALKKAEIGIAM Sbjct: 661 LSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAM 720 Query: 720 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 779 GSGTAVAK+A+EMVL+DDNF++IVAAVEEGRAIY+NMKQFIRYLISSNVGEVVCIFLTA Sbjct: 721 GSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAI 780 Query: 780 LGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAI 839 LG PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM K PR+P+E LISGWLFFRYLAI Sbjct: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRYLAI 840 Query: 840 GCYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMA 899 G YVG ATV AA WWF+ GP ++FYQL +FL+C EDNP F G+DC +FES +P TMA Sbjct: 841 GVYVGLATVAAATWWFVYDAEGPHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMA 900 Query: 900 LSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQIT 959 LSVLVTIEMCNALNS+SENQSLLRMPPW N WL+ ++ +SM+LHFLIL V PLPLIFQ+T Sbjct: 901 LSVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVT 960 Query: 960 PLNVTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQP 1000 PL+ QW++VL+ISLPVIL+DE LK+++RN++ C+ P Sbjct: 961 PLSGRQWVVVLQISLPVILLDEALKYLSRNHMH---ACLYP 998 >gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Homo sapiens] Length = 999 Score = 1555 bits (4027), Expect = 0.0 Identities = 767/992 (77%), Positives = 872/992 (87%), Gaps = 1/992 (0%) Query: 1 MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 ME AH +VL HF V GLS QV +ER+G NELP+EEGK+L ELV+EQFEDL Sbjct: 1 MEAAHLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDL 60 Query: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 LVRILLLAA +SFVLAWFEEGEET TAFVEP VI+LILVANAIVGVWQERNAE+AIEALK Sbjct: 61 LVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120 Query: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL 180 EYEPEMGKV R DRK VQRI+A+DIVPGDIVE+AVGDKVPAD+RL IKSTTLRVDQSIL Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180 Query: 181 TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 240 TGESVSV KHT+ +PDPRAVNQDKKNMLFSGTNI +GKA+GV VATG++TE+GKIR +M Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMA 240 Query: 241 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 300 A E ERTPLQ+KLDEFG QLS IS+IC+AVW+INIGHF DP HGGSW+RGA+YYFKIAV Sbjct: 241 AVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAV 300 Query: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 ALAVAAIPEGLPAVITTCLALGTRRMA+KNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 Query: 361 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 420 MSVCRMF++ + +C L+EFTI+G+TY P GEV + D+PV C Q+DGLVELATICALC Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420 Query: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK 480 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDT+L+ LS++ERA ACN+VIKQLM+ Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMR 480 Query: 481 KEFTLEFSRDRKSMSVYCTPNKPSRTSM-SKMFVKGAPEGVIDRCTHIRVGSTKVPMTSG 539 KEFTLEFSRDRKSMSVYCTP +P T SKMFVKGAPE VI+RC+ +RVGS P+T Sbjct: 481 KEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPT 540 Query: 540 VKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGML 599 +++I++ IR+WGSGSDTLRCLALAT D P R+E+M L+D + F++YET+LTFVGCVGML Sbjct: 541 SREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGML 600 Query: 600 DPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDE 659 DPPR EVA+ + C QAGIRV+MITGDNKGTAVAICRR+GIFG EDV KA+TGREFD+ Sbjct: 601 DPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREFDD 660 Query: 660 LNPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAM 719 L+P QR AC ARCFARVEP+HKS+IVE LQSF+EITAMTGDGVNDAPALKKAEIGIAM Sbjct: 661 LSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAM 720 Query: 720 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 779 GSGTAVAK+A+EMVL+DDNF++IVAAVEEGRAIY+NMKQFIRYLISSNVGEVVCIFLTA Sbjct: 721 GSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAI 780 Query: 780 LGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAI 839 LG PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM K PR+P+E LISGWLFFRYLAI Sbjct: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRYLAI 840 Query: 840 GCYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMA 899 G YVG ATV AA WWF+ GP ++FYQL +FL+C EDNP F G+DC +FES +P TMA Sbjct: 841 GVYVGLATVAAATWWFVYDAEGPHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMA 900 Query: 900 LSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQIT 959 LSVLVTIEMCNALNS+SENQSLLRMPPW N WL+ ++ +SM+LHFLIL V PLPLIFQ+T Sbjct: 901 LSVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVT 960 Query: 960 PLNVTQWLMVLKISLPVILMDETLKFVARNYL 991 PL+ QW++VL+ISLPVIL+DE LK+++RN++ Sbjct: 961 PLSGRQWVVVLQISLPVILLDEALKYLSRNHM 992 >gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Homo sapiens] Length = 998 Score = 1555 bits (4027), Expect = 0.0 Identities = 767/992 (77%), Positives = 872/992 (87%), Gaps = 1/992 (0%) Query: 1 MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 ME AH +VL HF V GLS QV +ER+G NELP+EEGK+L ELV+EQFEDL Sbjct: 1 MEAAHLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDL 60 Query: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 LVRILLLAA +SFVLAWFEEGEET TAFVEP VI+LILVANAIVGVWQERNAE+AIEALK Sbjct: 61 LVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120 Query: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL 180 EYEPEMGKV R DRK VQRI+A+DIVPGDIVE+AVGDKVPAD+RL IKSTTLRVDQSIL Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180 Query: 181 TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 240 TGESVSV KHT+ +PDPRAVNQDKKNMLFSGTNI +GKA+GV VATG++TE+GKIR +M Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMA 240 Query: 241 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 300 A E ERTPLQ+KLDEFG QLS IS+IC+AVW+INIGHF DP HGGSW+RGA+YYFKIAV Sbjct: 241 AVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAV 300 Query: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 ALAVAAIPEGLPAVITTCLALGTRRMA+KNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 Query: 361 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 420 MSVCRMF++ + +C L+EFTI+G+TY P GEV + D+PV C Q+DGLVELATICALC Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420 Query: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK 480 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDT+L+ LS++ERA ACN+VIKQLM+ Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMR 480 Query: 481 KEFTLEFSRDRKSMSVYCTPNKPSRTSM-SKMFVKGAPEGVIDRCTHIRVGSTKVPMTSG 539 KEFTLEFSRDRKSMSVYCTP +P T SKMFVKGAPE VI+RC+ +RVGS P+T Sbjct: 481 KEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPT 540 Query: 540 VKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGML 599 +++I++ IR+WGSGSDTLRCLALAT D P R+E+M L+D + F++YET+LTFVGCVGML Sbjct: 541 SREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGML 600 Query: 600 DPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDE 659 DPPR EVA+ + C QAGIRV+MITGDNKGTAVAICRR+GIFG EDV KA+TGREFD+ Sbjct: 601 DPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREFDD 660 Query: 660 LNPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAM 719 L+P QR AC ARCFARVEP+HKS+IVE LQSF+EITAMTGDGVNDAPALKKAEIGIAM Sbjct: 661 LSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAM 720 Query: 720 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 779 GSGTAVAK+A+EMVL+DDNF++IVAAVEEGRAIY+NMKQFIRYLISSNVGEVVCIFLTA Sbjct: 721 GSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAI 780 Query: 780 LGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAI 839 LG PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM K PR+P+E LISGWLFFRYLAI Sbjct: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRYLAI 840 Query: 840 GCYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMA 899 G YVG ATV AA WWF+ GP ++FYQL +FL+C EDNP F G+DC +FES +P TMA Sbjct: 841 GVYVGLATVAAATWWFVYDAEGPHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMA 900 Query: 900 LSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQIT 959 LSVLVTIEMCNALNS+SENQSLLRMPPW N WL+ ++ +SM+LHFLIL V PLPLIFQ+T Sbjct: 901 LSVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVT 960 Query: 960 PLNVTQWLMVLKISLPVILMDETLKFVARNYL 991 PL+ QW++VL+ISLPVIL+DE LK+++RN++ Sbjct: 961 PLSGRQWVVVLQISLPVILLDEALKYLSRNHM 992 >gi|239751049 PREDICTED: similar to ATPase, Ca++ transporting, fast twitch 1 [Homo sapiens] Length = 879 Score = 996 bits (2575), Expect = 0.0 Identities = 497/590 (84%), Positives = 550/590 (93%), Gaps = 1/590 (0%) Query: 1 MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 ME AH KT EE L +FGV+E+TGL+ +QVK+ E++G NELPAEEGKTL ELVIEQFEDL Sbjct: 256 MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL 315 Query: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLIL+ANAIVGVWQERNAENAIEALK Sbjct: 316 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 375 Query: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL 180 EYEPEMGKVYR DRKSVQRIKA+DIVPGDIVE+AVGDKVPADIR+ +IKSTTLRVDQSIL Sbjct: 376 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 435 Query: 181 TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 240 TGESVSVIKHT+PVPDPRAVNQDKKNMLFSGTNIAAGKA+G+V TGV TEIGKIRD+M Sbjct: 436 TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA 495 Query: 241 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 300 ATEQ++TPLQQKLDEFGEQLSKVISLIC+AVW+INIGHFNDPVHGGSW RGAIYYFKIAV Sbjct: 496 ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV 555 Query: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ Sbjct: 556 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 615 Query: 361 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 420 MSVC+MFI+D+V+GD C LNEF+ITGSTYAP GEV K+DKPV QYDGLVELATICALC Sbjct: 616 MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC 675 Query: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK 480 NDS+LD+NEAKGVYEKVGEATETALT LVEKMNVF+T+++ LSK+ERANACNSVI+QLMK Sbjct: 676 NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK 735 Query: 481 KEFTLEFSRDRKSMSVYCTPNKPSRTSM-SKMFVKGAPEGVIDRCTHIRVGSTKVPMTSG 539 KEFTLEFSRDRKSMSVYC+P K SR ++ +KMFVKGAPEGVIDRC ++RVG+T+VP+T Sbjct: 736 KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP 795 Query: 540 VKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETN 589 VK+KIM+VI+EWG+G DTLRCLALAT D P +REEM L+DSA F++YE + Sbjct: 796 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYEVS 845 >gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sapiens] Length = 949 Score = 478 bits (1231), Expect = e-134 Identities = 341/1008 (33%), Positives = 513/1008 (50%), Gaps = 131/1008 (12%) Query: 9 VEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLA 68 V EV + GL+ +V + G NE E + L + I QF++ L+ +LL + Sbjct: 31 VSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLAS 90 Query: 69 ACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGK 128 A IS ++ F++ V V +LI+V A V QE +E ++E L + P Sbjct: 91 AVISVLMHQFDDA-------VSITVAILIVVTVAFV---QEYRSEKSLEELSKLVPPECH 140 Query: 129 VYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSILTGESVSVI 188 R+ + ++ A+D+VPGD V ++VGD+VPAD+RL ++ L +D+S LTGE+ Sbjct: 141 CVREGK--LEHTLARDLVPGDTVCLSVGDRVPADLRL--FEAVDLSIDESSLTGETTPCS 196 Query: 189 KHTDPVPDPRAVNQD---KKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQE 245 K T P P A N D + N+ F GT + GKA GVV+ TG N+E G++ M A E Sbjct: 197 KVT--APQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254 Query: 246 RTPLQQKLDEFGEQLS----KVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVA 301 +TPLQ+ +D G+QLS +I +I + W++ + + F I+V+ Sbjct: 255 KTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLG--------------KDILEMFTISVS 300 Query: 302 LAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361 LAVAAIPEGLP V+T LALG RM KK AIV+ LP VETLGC +VICSDKTGTLT N+M Sbjct: 301 LAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEM 360 Query: 362 SVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCN 421 +V +F D + + +TG Y GEV D V+ + + +CN Sbjct: 361 TVTHIFTSDGLHAE--------VTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCN 412 Query: 422 DSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKK 481 D+ + N +G+ TE AL L KM L GL + + K Sbjct: 413 DAVIRNNTL------MGKPTEGALIALAMKMG-----LDGLQQ-----------DYIRKA 450 Query: 482 EFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGVK 541 E+ FS ++K M+V C ++ + F+KGA E VI CT + + +T + Sbjct: 451 EYP--FSSEQKWMAVKCV-HRTQQDRPEICFMKGAYEQVIKYCTTYQSKGQTLTLTQ--Q 505 Query: 542 QKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLDP 601 Q+ + + GS LR LALA+ LTF+G VG++DP Sbjct: 506 QRDVYQQEKARMGSAGLRVLALASGPEL------------------GQLTFLGLVGIIDP 547 Query: 602 PRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDELN 661 PR V +V +G+ + MITGD++ TAVAI R+G++ + TS++ +G E D ++ Sbjct: 548 PRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSK----TSQSVSGEEIDAMD 603 Query: 662 PSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG- 720 F R P HK KI++ LQ + AMTGDGVNDA ALK A+IG+AMG Sbjct: 604 VQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQ 663 Query: 721 SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL 780 +GT V K A++M+L DD+F TI++A+EEG+ IYNN+K F+R+ +S+++ + I L + Sbjct: 664 TGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLM 723 Query: 781 GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG 840 FP L +Q+LW+N++ DG PA +LG P D D++ KPPRN K+ +++ L + L Sbjct: 724 NFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSS 783 Query: 841 CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMAL 900 + T L F + DN +P TM Sbjct: 784 IIIVCGT---------------------LFVFWRELRDN----------VITPRDTTMTF 812 Query: 901 SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP 960 + V +M NAL+S S+ +S+ + N ++ S+ L++Y PL +FQ Sbjct: 813 TCFVFFDMFNALSSRSQTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTES 872 Query: 961 LNVTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQPATKSCSFS 1008 L++ L +L ++ V ++ E +K V R+ +E +Q S S S Sbjct: 873 LSILDLLFLLGLTSSVCIVAEIIKKVERS-----REKIQKHVSSTSSS 915 >gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sapiens] Length = 919 Score = 478 bits (1231), Expect = e-134 Identities = 341/1008 (33%), Positives = 513/1008 (50%), Gaps = 131/1008 (12%) Query: 9 VEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLA 68 V EV + GL+ +V + G NE E + L + I QF++ L+ +LL + Sbjct: 31 VSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLAS 90 Query: 69 ACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGK 128 A IS ++ F++ V V +LI+V A V QE +E ++E L + P Sbjct: 91 AVISVLMHQFDDA-------VSITVAILIVVTVAFV---QEYRSEKSLEELSKLVPPECH 140 Query: 129 VYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSILTGESVSVI 188 R+ + ++ A+D+VPGD V ++VGD+VPAD+RL ++ L +D+S LTGE+ Sbjct: 141 CVREGK--LEHTLARDLVPGDTVCLSVGDRVPADLRL--FEAVDLSIDESSLTGETTPCS 196 Query: 189 KHTDPVPDPRAVNQD---KKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQE 245 K T P P A N D + N+ F GT + GKA GVV+ TG N+E G++ M A E Sbjct: 197 KVT--APQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254 Query: 246 RTPLQQKLDEFGEQLS----KVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVA 301 +TPLQ+ +D G+QLS +I +I + W++ + + F I+V+ Sbjct: 255 KTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLG--------------KDILEMFTISVS 300 Query: 302 LAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361 LAVAAIPEGLP V+T LALG RM KK AIV+ LP VETLGC +VICSDKTGTLT N+M Sbjct: 301 LAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEM 360 Query: 362 SVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCN 421 +V +F D + + +TG Y GEV D V+ + + +CN Sbjct: 361 TVTHIFTSDGLHAE--------VTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCN 412 Query: 422 DSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKK 481 D+ + N +G+ TE AL L KM L GL + + K Sbjct: 413 DAVIRNNTL------MGKPTEGALIALAMKMG-----LDGLQQ-----------DYIRKA 450 Query: 482 EFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGVK 541 E+ FS ++K M+V C ++ + F+KGA E VI CT + + +T + Sbjct: 451 EYP--FSSEQKWMAVKCV-HRTQQDRPEICFMKGAYEQVIKYCTTYQSKGQTLTLTQ--Q 505 Query: 542 QKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLDP 601 Q+ + + GS LR LALA+ LTF+G VG++DP Sbjct: 506 QRDVYQQEKARMGSAGLRVLALASGPEL------------------GQLTFLGLVGIIDP 547 Query: 602 PRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDELN 661 PR V +V +G+ + MITGD++ TAVAI R+G++ + TS++ +G E D ++ Sbjct: 548 PRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSK----TSQSVSGEEIDAMD 603 Query: 662 PSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG- 720 F R P HK KI++ LQ + AMTGDGVNDA ALK A+IG+AMG Sbjct: 604 VQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQ 663 Query: 721 SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL 780 +GT V K A++M+L DD+F TI++A+EEG+ IYNN+K F+R+ +S+++ + I L + Sbjct: 664 TGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLM 723 Query: 781 GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG 840 FP L +Q+LW+N++ DG PA +LG P D D++ KPPRN K+ +++ L + L Sbjct: 724 NFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSS 783 Query: 841 CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMAL 900 + T L F + DN +P TM Sbjct: 784 IIIVCGT---------------------LFVFWRELRDN----------VITPRDTTMTF 812 Query: 901 SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP 960 + V +M NAL+S S+ +S+ + N ++ S+ L++Y PL +FQ Sbjct: 813 TCFVFFDMFNALSSRSQTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTES 872 Query: 961 LNVTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQPATKSCSFS 1008 L++ L +L ++ V ++ E +K V R+ +E +Q S S S Sbjct: 873 LSILDLLFLLGLTSSVCIVAEIIKKVERS-----REKIQKHVSSTSSS 915 >gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sapiens] Length = 939 Score = 478 bits (1229), Expect = e-134 Identities = 336/989 (33%), Positives = 506/989 (51%), Gaps = 126/989 (12%) Query: 9 VEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLA 68 V EV + GL+ +V + G NE E + L + I QF++ L+ +LL + Sbjct: 31 VSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLAS 90 Query: 69 ACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGK 128 A IS ++ F++ V V +LI+V A V QE +E ++E L + P Sbjct: 91 AVISVLMHQFDDA-------VSITVAILIVVTVAFV---QEYRSEKSLEELSKLVPPECH 140 Query: 129 VYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSILTGESVSVI 188 R+ + ++ A+D+VPGD V ++VGD+VPAD+RL ++ L +D+S LTGE+ Sbjct: 141 CVREGK--LEHTLARDLVPGDTVCLSVGDRVPADLRL--FEAVDLSIDESSLTGETTPCS 196 Query: 189 KHTDPVPDPRAVNQD---KKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQE 245 K T P P A N D + N+ F GT + GKA GVV+ TG N+E G++ M A E Sbjct: 197 KVT--APQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254 Query: 246 RTPLQQKLDEFGEQLS----KVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVA 301 +TPLQ+ +D G+QLS +I +I + W++ + + F I+V+ Sbjct: 255 KTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLG--------------KDILEMFTISVS 300 Query: 302 LAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361 LAVAAIPEGLP V+T LALG RM KK AIV+ LP VETLGC +VICSDKTGTLT N+M Sbjct: 301 LAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEM 360 Query: 362 SVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCN 421 +V +F D + + +TG Y GEV D V+ + + +CN Sbjct: 361 TVTHIFTSDGLHAE--------VTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCN 412 Query: 422 DSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKK 481 D+ + N +G+ TE AL L KM L GL + + K Sbjct: 413 DAVIRNNTL------MGKPTEGALIALAMKMG-----LDGLQQ-----------DYIRKA 450 Query: 482 EFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGVK 541 E+ FS ++K M+V C ++ + F+KGA E VI CT + + +T + Sbjct: 451 EYP--FSSEQKWMAVKCV-HRTQQDRPEICFMKGAYEQVIKYCTTYQSKGQTLTLTQ--Q 505 Query: 542 QKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLDP 601 Q+ + + GS LR LALA+ LTF+G VG++DP Sbjct: 506 QRDVYQQEKARMGSAGLRVLALASGPEL------------------GQLTFLGLVGIIDP 547 Query: 602 PRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDELN 661 PR V +V +G+ + MITGD++ TAVAI R+G++ + TS++ +G E D ++ Sbjct: 548 PRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSK----TSQSVSGEEIDAMD 603 Query: 662 PSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG- 720 F R P HK KI++ LQ + AMTGDGVNDA ALK A+IG+AMG Sbjct: 604 VQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQ 663 Query: 721 SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL 780 +GT V K A++M+L DD+F TI++A+EEG+ IYNN+K F+R+ +S+++ + I L + Sbjct: 664 TGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLM 723 Query: 781 GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG 840 FP L +Q+LW+N++ DG PA +LG P D D++ KPPRN K+ +++ L + L Sbjct: 724 NFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSS 783 Query: 841 CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMAL 900 + T L F + DN +P TM Sbjct: 784 IIIVCGT---------------------LFVFWRELRDN----------VITPRDTTMTF 812 Query: 901 SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP 960 + V +M NAL+S S+ +S+ + N ++ S+ L++Y PL +FQ Sbjct: 813 TCFVFFDMFNALSSRSQTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTES 872 Query: 961 LNVTQWLMVLKISLPVILMDETLKFVARN 989 L++ L +L ++ V ++ E +K V R+ Sbjct: 873 LSILDLLFLLGLTSSVCIVAEIIKKVERS 901 >gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sapiens] Length = 888 Score = 468 bits (1204), Expect = e-131 Identities = 329/963 (34%), Positives = 492/963 (51%), Gaps = 126/963 (13%) Query: 9 VEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLA 68 V EV + GL+ +V + G NE E + L + I QF++ L+ +LL + Sbjct: 31 VSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLAS 90 Query: 69 ACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGK 128 A IS ++ F++ V V +LI+V A V QE +E ++E L + P Sbjct: 91 AVISVLMHQFDDA-------VSITVAILIVVTVAFV---QEYRSEKSLEELSKLVPPECH 140 Query: 129 VYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSILTGESVSVI 188 R+ + ++ A+D+VPGD V ++VGD+VPAD+RL ++ L +D+S LTGE+ Sbjct: 141 CVREGK--LEHTLARDLVPGDTVCLSVGDRVPADLRL--FEAVDLSIDESSLTGETTPCS 196 Query: 189 KHTDPVPDPRAVNQD---KKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQE 245 K T P P A N D + N+ F GT + GKA GVV+ TG N+E G++ M A E Sbjct: 197 KVT--APQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254 Query: 246 RTPLQQKLDEFGEQLS----KVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVA 301 +TPLQ+ +D G+QLS +I +I + W++ + + F I+V+ Sbjct: 255 KTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLG--------------KDILEMFTISVS 300 Query: 302 LAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361 LAVAAIPEGLP V+T LALG RM KK AIV+ LP VETLGC +VICSDKTGTLT N+M Sbjct: 301 LAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEM 360 Query: 362 SVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCN 421 +V +F D + + +TG Y GEV D V+ + + +CN Sbjct: 361 TVTHIFTSDGLHAE--------VTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCN 412 Query: 422 DSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKK 481 D+ + N +G+ TE AL L KM L GL + + K Sbjct: 413 DAVIRNNTL------MGKPTEGALIALAMKMG-----LDGLQQ-----------DYIRKA 450 Query: 482 EFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGVK 541 E+ FS ++K M+V C ++ + F+KGA E VI CT + + +T + Sbjct: 451 EYP--FSSEQKWMAVKCV-HRTQQDRPEICFMKGAYEQVIKYCTTYQSKGQTLTLTQ--Q 505 Query: 542 QKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLDP 601 Q+ + + GS LR LALA+ LTF+G VG++DP Sbjct: 506 QRDVYQQEKARMGSAGLRVLALASGPEL------------------GQLTFLGLVGIIDP 547 Query: 602 PRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDELN 661 PR V +V +G+ + MITGD++ TAVAI R+G++ + TS++ +G E D ++ Sbjct: 548 PRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSK----TSQSVSGEEIDAMD 603 Query: 662 PSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG- 720 F R P HK KI++ LQ + AMTGDGVNDA ALK A+IG+AMG Sbjct: 604 VQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQ 663 Query: 721 SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL 780 +GT V K A++M+L DD+F TI++A+EEG+ IYNN+K F+R+ +S+++ + I L + Sbjct: 664 TGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLM 723 Query: 781 GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG 840 FP L +Q+LW+N++ DG PA +LG P D D++ KPPRN K+ +++ L + L Sbjct: 724 NFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSS 783 Query: 841 CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMAL 900 + T L F + DN +P TM Sbjct: 784 IIIVCGT---------------------LFVFWRELRDN----------VITPRDTTMTF 812 Query: 901 SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP 960 + V +M NAL+S S+ +S+ + N ++ S+ L++Y PL +FQ Sbjct: 813 TCFVFFDMFNALSSRSQTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTES 872 Query: 961 LNV 963 L++ Sbjct: 873 LSI 875 >gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo sapiens] Length = 946 Score = 443 bits (1139), Expect = e-124 Identities = 323/996 (32%), Positives = 501/996 (50%), Gaps = 120/996 (12%) Query: 10 EEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLAA 69 E++ F V+ TGLS V + + G NE A+ + + + ++QF++ L+ +LL +A Sbjct: 63 EDLARAFCVDLHTGLSEFSVTQRRLAHGWNEFVADNSEPVWKKYLDQFKNPLILLLLGSA 122 Query: 70 CISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGKV 129 +S + +E+ TA +L++V A + QE +E ++E L + P Sbjct: 123 LVSVLTKEYEDAVSIATA-------VLVVVTVAFI---QEYRSEKSLEELTKMVPPECNC 172 Query: 130 YRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSILTGESVSVIK 189 R+ + +Q + A+++VPGD+V +++GD++PADIRLT + T L VD+S TGE+ K Sbjct: 173 LREGK--LQHLLARELVPGDVVSLSIGDRIPADIRLTEV--TDLLVDESSFTGEAEPCSK 228 Query: 190 HTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQERTPL 249 P+ + N++F GT + G+ GVV+ TG +++ G++ M A E +TPL Sbjct: 229 TDSPLTGGGDLTT-LSNIVFMGTLVQYGRGQGVVIGTGESSQFGEVFKMMQAEETPKTPL 287 Query: 250 QQKLDEFGEQLSK----VISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVA 305 Q+ +D G+QL+ +I LI + W S + + F I V+LAVA Sbjct: 288 QKSMDRLGKQLTLFSFGIIGLIMLIGW--------------SQGKQLLSMFTIGVSLAVA 333 Query: 306 AIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCR 365 AIPEGLP V+ L LG RMAKK IV+ LP VETLGC SV+CSDKTGTLT N+M+V + Sbjct: 334 AIPEGLPIVVMVTLVLGVLRMAKKRVIVKKLPIVETLGCCSVLCSDKTGTLTANEMTVTQ 393 Query: 366 MFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCNDSAL 425 + D + + + P EV K+ V+ + LVE + N++ + Sbjct: 394 LVTSDGLRAEVSGVGYDGQGTVCLLPSKEVIKEFSNVSVGK---LVEAGCVA---NNAVI 447 Query: 426 DYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKKEFTL 485 N +G+ TE AL L KM++ D + NS I+ KKE + Sbjct: 448 RKNAV------MGQPTEGALMALAMKMDLSDIK-------------NSYIR---KKE--I 483 Query: 486 EFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGVKQKIM 545 FS ++K M+V C+ + + F+KGA E VI CT G +P+T +Q+ Sbjct: 484 PFSSEQKWMAVKCSLKTEDQEDI--YFMKGALEEVIRYCTMYNNGGIPLPLTP--QQRSF 539 Query: 546 SVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLDPPRIE 605 + E GS LR LALA+ R LTF+G VG++DPPR+ Sbjct: 540 CLQEEKRMGSLGLRVLALASGPELGR------------------LTFLGLVGIIDPPRVG 581 Query: 606 VASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDELNPSAQ 665 V +V++ ++G+ V MITGD TA+AI R IG+ +A +G E D + Sbjct: 582 VKEAVQVLSESGVSVKMITGDALETALAIGRNIGLCNGK----LQAMSGEEVDSVEKGEL 637 Query: 666 RDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTA 724 D F R P HK KI++ LQ I AMTGDGVNDA ALK A+IGIAMG +GT Sbjct: 638 ADRVGKVSVFFRTSPKHKLKIIKALQESGAIVAMTGDGVNDAVALKSADIGIAMGQTGTD 697 Query: 725 VAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPE 784 V+K A+ M+L DD+FS I+ AVEEG+ I+ N+K F+R+ +S+++ + I L+ P Sbjct: 698 VSKEAANMILVDDDFSAIMNAVEEGKGIFYNIKNFVRFQLSTSISALSLITLSTVFNLPS 757 Query: 785 ALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVG 844 L +Q+LW+N++ DG PA +LG P D D +PPR+ ++ ++S L + L + Sbjct: 758 PLNAMQILWINIIMDGPPAQSLGVEPVDKDAFRQPPRSVRDTILSRALILKILMSAAIII 817 Query: 845 AATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMALSVLV 904 + T+ F+ KE D +P TM + V Sbjct: 818 SGTL-----------------------FIFWKEMPEDRA-------STPRTTTMTFTCFV 847 Query: 905 TIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVT 964 ++ NAL S+ + + + N + S+ S+ ++Y+ PL +FQ L Sbjct: 848 FFDLFNALTCRSQTKLIFEIGFLRNHMFLYSVLGSILGQLAVIYIPPLQRVFQTENLGAL 907 Query: 965 QWLMVLKISLPVILMDETLKFVARNYLEPGKECVQP 1000 L + ++ V ++ E LK + P + + P Sbjct: 908 DLLFLTGLASSVFILSELLKLCEKYCCSPKRVQMHP 943 >gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapiens] Length = 1029 Score = 372 bits (956), Expect = e-103 Identities = 302/1031 (29%), Positives = 486/1031 (47%), Gaps = 109/1031 (10%) Query: 5 HTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELP----AEEGKTLLELVIEQFEDL 60 H T+EE+ + V+ + G S ++ K++ R G N + E + + F L Sbjct: 52 HKLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTTPEWVKFCKQLFGGFSLL 111 Query: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 L +L + +F E E T V+ ++++ +QE + +E+ K Sbjct: 112 LWTGAILCFVAYSIQIYFNE-EPTKDNLYLSIVLSVVVIVTGCFSYYQEAKSSKIMESFK 170 Query: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL 180 P+ V R K +I +++V GD+VEI GD+VPAD+RL S + +VD S L Sbjct: 171 NMVPQQALVIRGGEK--MQINVQEVVLGDLVEIKGGDRVPADLRLISAQGC--KVDNSSL 226 Query: 181 TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 240 TGES + D + + +N+ F TN G A G+V+ATG +T +G+I Sbjct: 227 TGESEPQSRSPDFTHENPL---ETRNICFFSTNCVEGTARGIVIATGDSTVMGRIASLTS 283 Query: 241 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 300 +TP+ +++ F ++ V + + + +++ + G W+ I+ + Sbjct: 284 GLAVGQTPIAAEIEHFIHLITVVAVFLGVTFFALSL------LLGYGWLEAIIFL----I 333 Query: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 + VA +PEGL A +T CL L +RMA+KN +V++L +VETLG TS ICSDKTGTLT N+ Sbjct: 334 GIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNR 393 Query: 361 MSVCRM-FILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICAL 419 M+V M F + E DT TG T+ D LA I L Sbjct: 394 MTVAHMWFDMTVYEADTTEEQ----TGKTFTKSS--------------DTWFMLARIAGL 435 Query: 420 CNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIK 476 CN + N+ K G+A+E+AL L IE++ + + ++ Sbjct: 436 CNRADFKANQEILPIAKRATTGDASESAL----------------LKFIEQSYSSVAEMR 479 Query: 477 QLMKKEFTLEFSRDRK-SMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVP 535 + K + F+ K MS++ + S+T + + +KGAPE +++ C+ + + Sbjct: 480 EKNPKVAEIPFNSTNKYQMSIHLREDS-SQTHV--LMMKGAPERILEFCSTFLLNGQEYS 536 Query: 536 MTSGVKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGC 595 M +K+ + E G + + + + D NF NL FVG Sbjct: 537 MNDEMKEAFQNAYLELGGLGERVLGFCFLNLPSSFSKGFPFNTDEINFPM--DNLCFVGL 594 Query: 596 VGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFT-- 653 + M+DPPR V +V CR AGI+VIM+TGD+ TA AI + +GI + + + Sbjct: 595 ISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGTETAEEVAARL 654 Query: 654 ------------------GREFDELNPSAQRDACLNAR---CFARVEPSHKSKIVEFLQS 692 G E ++ S Q D L FAR P K IVE Q Sbjct: 655 KIPISKVDASAAKAIVVHGAELKDIQ-SKQLDQILQNHPEIVFARTSPQQKLIIVEGCQR 713 Query: 693 FDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRA 751 + A+TGDGVND+PALKKA+IGIAMG SG+ V+K A++M+L DDNF++IV VEEGR Sbjct: 714 LGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRL 773 Query: 752 IYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPP 811 I++N+K+ I Y ++SN+ E+ + LG P L + +L ++L TD +PA +L + Sbjct: 774 IFDNLKKSIMYTLTSNIPEITPFLMFIILGIPLPLGTITILCIDLGTDMVPAISLAYESA 833 Query: 812 DLDIMNKPPRNPK-EPLISGWLF-FRYLAIGCYVGAATVGAAAWWFIAADGGPR------ 863 + DIM + PRNPK + L++ L Y IG A G ++ I A+ G R Sbjct: 834 ESDIMKRLPRNPKTDNLVNHRLIGMAYGQIGMI--QALAGFFTYFVILAENGFRPVDLLG 891 Query: 864 VSFYQLSHFLQCKEDNP----DFEGVDCAIFESPYPMTMALSVLVTIEMCNALNSLSENQ 919 + + +L ED+ +E F T +V ++ + + S + Sbjct: 892 IRLHWEDKYLNDLEDSYGQQWTYEQRKVVEFTC---QTAFFVTIVVVQWADLIISKTRRN 948 Query: 920 SLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISLPVILM 979 SL + + + G + ++ FL Y + + ++ PL +T WL + S+ + + Sbjct: 949 SLFQQGMRNKVLIFGILEETLLAAFL-SYTPGMDVALRMYPLKITWWLCAIPYSILIFVY 1007 Query: 980 DETLKFVARNY 990 DE K + R + Sbjct: 1008 DEIRKLLIRQH 1018 >gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens] Length = 1035 Score = 371 bits (953), Expect = e-102 Identities = 304/1034 (29%), Positives = 482/1034 (46%), Gaps = 112/1034 (10%) Query: 3 NAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLV 62 N H +V E+ + + + GLS +L R G N L G Q L Sbjct: 53 NDHQLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQ 112 Query: 63 RILLLAACISFVLAWFEEGEETITAFVEPFV---ILLILVANAIVGVWQERNAENAIEAL 119 ++ +AA I + + E +T ++ ++ ++V G +QE + N I + Sbjct: 113 CLMWVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASF 172 Query: 120 KEYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSI 179 K P+ V R K +I A +V GD+VE+ GD+VPADIR+ + + +VD S Sbjct: 173 KNLVPQQATVIRDGDKF--QINADQLVVGDLVEMKGGDRVPADIRILAAQGC--KVDNSS 228 Query: 180 LTGESVSVIK-----HTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGK 234 LTGES + H P+ + +N+ F T G G+VV TG T IG+ Sbjct: 229 LTGESEPQTRSPECTHESPL--------ETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGR 280 Query: 235 IRDEMVATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIY 294 I E E+TP+ +++ F + ++ + L +I+ + G +++R ++ Sbjct: 281 IASLASGVENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAM------CIGYTFLRAMVF 334 Query: 295 YFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTG 354 + +A+ VA +PEGL A +T CL+L +R+A KN +V++L +VETLG TSVICSDKTG Sbjct: 335 F----MAIVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTG 390 Query: 355 TLTTNQMSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELA 414 TLT N+M+V ++ + + + ++ +G T+ E + L Sbjct: 391 TLTQNRMTVSHLWFDNHIHTADTTEDQ---SGQTFDQSSETWR--------------ALC 433 Query: 415 TICALCNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTELKGLSKIERANAC 471 + LCN +A + K +G+A+ETAL LK S++ NA Sbjct: 434 RVLTLCNRAAFKSGQDAVPVPKRIVIGDASETAL-------------LK-FSELTLGNAM 479 Query: 472 NSVIKQLMKKEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGS 531 + K + F+ K T P R + +KGAPE V++RC+ I + Sbjct: 480 G--YRDRFPKVCEIPFNSTNKFQLSIHTLEDP-RDPRHLLVMKGAPERVLERCSSILIKG 536 Query: 532 TKVPMTSGVKQKIMSVIREWGS-GSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNL 590 ++P+ ++ + G G L L ++ ++ NF + L Sbjct: 537 QELPLDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNF--PSSGL 594 Query: 591 TFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQD----ED 646 F G V M+DPPR V +V CR AGIRVIM+TGD+ TA AI +GI + ED Sbjct: 595 CFAGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVED 654 Query: 647 VTSK----------------AFTGREFDELNPSAQRDACLN--ARCFARVEPSHKSKIVE 688 + ++ G + +++PS +A FAR P K IVE Sbjct: 655 IAARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVE 714 Query: 689 FLQSFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVE 747 Q I A+TGDGVND+PALKKA+IG+AMG +G+ AK A++M+L DDNF++IV VE Sbjct: 715 SCQRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVE 774 Query: 748 EGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALG 807 +GR I++N+K+ I Y ++ N+ E+ + + P L + +L++ L TD P+ +L Sbjct: 775 QGRLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLA 834 Query: 808 FNPPDLDIMNKPPRNPK------EPLISGWLFFRYLAIGCYVGAA---TVGAAAWWFIAA 858 + + DIM+ PRNPK EPL + + +F+ AI + G T A WF Sbjct: 835 YEKAESDIMHLRPRNPKRDRLVNEPL-AAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLL 893 Query: 859 DGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMALSV-LVTIEMCNALNSL-- 915 G R + H LQ D D G + + Y +V ++IE+C + L Sbjct: 894 CVGLRAQWE--DHHLQ---DLQDSYGQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIR 948 Query: 916 -SENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISL 974 + S + + N LV +I + + + Y +P IF P+ WL+ L + Sbjct: 949 KTRRLSAFQQGFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGI 1008 Query: 975 PVILMDETLKFVAR 988 + + DE K R Sbjct: 1009 LIFVYDEIRKLGVR 1022 >gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens] Length = 1020 Score = 370 bits (950), Expect = e-102 Identities = 299/1032 (28%), Positives = 494/1032 (47%), Gaps = 110/1032 (10%) Query: 5 HTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNEL-PAEEGKTLLELVIEQFEDLLVR 63 H +++E+ + V+ S GL+ ++ + + R G N L P ++ + F + Sbjct: 42 HKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSI- 100 Query: 64 ILLLAACISFVLAWFE---EGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 +L + A + F+ + E E + V+ +++ +QE + +++ K Sbjct: 101 LLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFK 160 Query: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL 180 P+ V R+ K +I A+++V GD+VE+ GD+VPAD+R+ I S +VD S L Sbjct: 161 NMVPQQALVIREGEK--MQINAEEVVVGDLVEVKGGDRVPADLRI--ISSHGCKVDNSSL 216 Query: 181 TGESVSVIK-----HTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKI 235 TGES + H +P+ + +N+ F TN G A G+V+ATG T +G+I Sbjct: 217 TGESEPQTRSPEFTHENPL--------ETRNICFFSTNCVEGTARGIVIATGDRTVMGRI 268 Query: 236 RDEMVATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYY 295 E RTP+ +++ F + ++ V + ++ +++++ + G SW+ I+ Sbjct: 269 ATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSL------ILGYSWLEAVIFL 322 Query: 296 FKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGT 355 + + VA +PEGL A +T CL L +RMA+KN +V++L +VETLG TS ICSDKTGT Sbjct: 323 ----IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGT 378 Query: 356 LTTNQMSVCRMFILDRV-EGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELA 414 LT N+M+V M+ +++ E DT +G+T+ DK + L +A Sbjct: 379 LTQNRMTVAHMWFDNQIHEADTTEDQ----SGATF---------DK--RSPTWTALSRIA 423 Query: 415 TICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSV 474 +C A N + + G+A+E+AL +E +C SV Sbjct: 424 GLCNRAVFKAGQENISVSKRDTAGDASESALLKCIEL------------------SCGSV 465 Query: 475 IKQLMKKEFTLEF---SRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGS 531 K + E S ++ +S++ + P + +KGAPE ++DRC+ I V Sbjct: 466 RKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQS---HVLVMKGAPERILDRCSTILVQG 522 Query: 532 TKVPMTSGVKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETN-L 590 ++P+ ++ + E G + R L + P + + + + + T L Sbjct: 523 KEIPLDKEMQDAFQNAYMELGGLGE--RVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKL 580 Query: 591 TFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSK 650 FVG + M+DPPR V +V CR AGI+VIM+TGD+ TA AI + +GI + + Sbjct: 581 CFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVED 640 Query: 651 --AFTGREFDELNP-----------------SAQRDACLNARC---FARVEPSHKSKIVE 688 A ++NP S Q D L FAR P K IVE Sbjct: 641 IAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVE 700 Query: 689 FLQSFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVE 747 Q I A+TGDGVND+PALKKA+IGIAMG SG+ V+K A++M+L DDNF++IV VE Sbjct: 701 GCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVE 760 Query: 748 EGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALG 807 EGR I++N+K+ I Y ++SN+ E+ L P L V +L ++L TD +PA +L Sbjct: 761 EGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLA 820 Query: 808 FNPPDLDIMNKPPRNPK-EPLISGWLF-FRYLAIGCYVGAATVGAAAWWFIAADGG---P 862 + + DIM + PRN + + L++ L Y IG A G ++ I A+ G Sbjct: 821 YEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMI--QALGGFFTYFVILAENGFLPS 878 Query: 863 RVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYP----MTMALSVLVTIEMCNALNSLSEN 918 R+ +L + D D G + + T + +V ++ + + + Sbjct: 879 RLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRR 938 Query: 919 QSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISLPVIL 978 S+ + +N L+ + +L + Y + + ++ PL VT W SL + + Sbjct: 939 NSVFQQ-GMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFI 997 Query: 979 MDETLKFVARNY 990 DE K + R Y Sbjct: 998 YDEVRKLILRRY 1009 >gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens] Length = 1013 Score = 363 bits (932), Expect = e-100 Identities = 268/859 (31%), Positives = 434/859 (50%), Gaps = 101/859 (11%) Query: 5 HTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNEL-PAEEGKTLLELVIEQFEDLLVR 63 H +VEEV + + GL+ + +++ R G N L P ++ + F + Sbjct: 34 HKMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTTPEWVKFCRQLFGGFSI- 92 Query: 64 ILLLAACISFVLAWFEEGEETITAFVEPF---VILLILVANAIVGVWQERNAENAIEALK 120 +L + A + F+ + G E + + V+ +++ +QE + +E+ K Sbjct: 93 LLWIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVIITGCFSYYQEAKSSKIMESFK 152 Query: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL 180 P+ V R+ K ++ A+++V GD+VEI GD+VPAD+R+ S +VD S L Sbjct: 153 NMVPQQALVIREGEK--MQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGC--KVDNSSL 208 Query: 181 TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 240 TGES + D D + +N+ F TN G A GVVVATG T +G+I Sbjct: 209 TGESEPQTRSPDCTHDNPL---ETRNITFFSTNCVEGTARGVVVATGDRTVMGRIATLAS 265 Query: 241 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 300 E +TP+ +++ F + ++ V + ++ +I+++ + G +W+ I+ + Sbjct: 266 GLEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSL------ILGYTWLEAVIFL----I 315 Query: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 + VA +PEGL A +T CL L +RMA+KN +V++L +VETLG TS ICSDKTGTLT N+ Sbjct: 316 GIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNR 375 Query: 361 MSVCRMFILDRV-EGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICAL 419 M+V M+ +++ E DT +G+++ DK + H + V L+ I L Sbjct: 376 MTVAHMWFDNQIHEADTTEDQ----SGTSF---------DK--SSHTW---VALSHIAGL 417 Query: 420 CNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIK 476 CN + + K G+A+E+AL L IE ++ +++ Sbjct: 418 CNRAVFKGGQDNIPVLKRDVAGDASESAL----------------LKCIELSSGSVKLMR 461 Query: 477 QLMKKEFTLEFSRDRK-SMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVP 535 + KK + F+ K +S++ T + + + +KGAPE ++DRC+ I + + P Sbjct: 462 ERNKKVAEIPFNSTNKYQLSIHETEDPNDNRYL--LVMKGAPERILDRCSTILLQGKEQP 519 Query: 536 MTSGVKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYET-NLTFVG 594 + +K+ + E G + R L + P + + + + T NL FVG Sbjct: 520 LDEEMKEAFQNAYLELGGLGE--RVLGFCHYYLPEEQFPKGFAFDCDDVNFTTDNLCFVG 577 Query: 595 CVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQD----EDVTS- 649 + M+DPPR V +V CR AGI+VIM+TGD+ TA AI + +GI + ED+ + Sbjct: 578 LMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAAR 637 Query: 650 -----------------------KAFTGREFDELNPSAQRDACLNARCFARVEPSHKSKI 686 K FT + DE+ + FAR P K I Sbjct: 638 LNIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNHTEIV------FARTSPQQKLII 691 Query: 687 VEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAA 745 VE Q I A+TGDGVND+PALKKA+IG+AMG +G+ V+K A++M+L DDNF++IV Sbjct: 692 VEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTG 751 Query: 746 VEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATA 805 VEEGR I++N+K+ I Y ++SN+ E+ L P L + +L ++L TD +PA + Sbjct: 752 VEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTITILCIDLGTDMVPAIS 811 Query: 806 LGFNPPDLDIMNKPPRNPK 824 L + + DIM + PRNP+ Sbjct: 812 LAYEAAESDIMKRQPRNPR 830 >gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapiens] Length = 1023 Score = 357 bits (916), Expect = 3e-98 Identities = 299/1036 (28%), Positives = 481/1036 (46%), Gaps = 121/1036 (11%) Query: 5 HTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNEL-PAEEGKTLLELVIEQFEDLLVR 63 H +++E+ +G + S GL+ + ++ R G N L P ++ + F + Sbjct: 44 HKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSM- 102 Query: 64 ILLLAACISF----VLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEAL 119 +L + A + F + A EE + ++ V+ +++ +QE + +E+ Sbjct: 103 LLWIGAILCFLAYSIQAATEEEPQNDNLYLG-VVLSAVVIITGCFSYYQEAKSSKIMESF 161 Query: 120 KEYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSI 179 K P+ V R K I A+++V GD+VE+ GD++PAD+R+ I + +VD S Sbjct: 162 KNMVPQQALVIRNGEK--MSINAEEVVVGDLVEVKGGDRIPADLRI--ISANGCKVDNSS 217 Query: 180 LTGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEM 239 LTGES + D + + +N+ F TN G A G+VV TG T +G+I Sbjct: 218 LTGESEPQTRSPDFTNENPL---ETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLA 274 Query: 240 VATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIA 299 E +TP+ +++ F ++ V + ++ +I+++ + +W+ I+ Sbjct: 275 SGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSL------ILEYTWLEAVIFL---- 324 Query: 300 VALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTN 359 + + VA +PEGL A +T CL L +RMA+KN +V++L +VETLG TS ICSDKTGTLT N Sbjct: 325 IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQN 384 Query: 360 QMSVCRMFILDRV-EGDTCSLNE---FTITGSTYAPIGEVHKDDKPVNCHQYDGLVELAT 415 +M+V M+ +++ E DT F T +T+ + L+ Sbjct: 385 RMTVAHMWFDNQIHEADTTENQSGVSFDKTSATW---------------------LALSR 423 Query: 416 ICALCNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTELKGLSKIERANACN 472 I LCN + N+ K G+A+E+AL +E C Sbjct: 424 IAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIEL------------------CCG 465 Query: 473 SV--IKQLMKKEFTLEFSRDRK-SMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRV 529 SV +++ K + F+ K +S++ PN + + +KGAPE ++DRC+ I + Sbjct: 466 SVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHL--LVMKGAPERILDRCSSILL 523 Query: 530 GSTKVPMTSGVKQKIMSVIREWGS-GSDTLRCLALATHDNPLRREEMHLEDSANFIKYET 588 + P+ +K + E G G L L D D NF Sbjct: 524 HGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPI--D 581 Query: 589 NLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVT 648 NL FVG + M+DPPR V +V CR AGI+VIM+TGD+ TA AI + +GI + + Sbjct: 582 NLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETV 641 Query: 649 SK--AFTGREFDELNP-----------------SAQRDACLNARC---FARVEPSHKSKI 686 A ++NP S Q D L FAR P K I Sbjct: 642 EDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFARTSPQQKLII 701 Query: 687 VEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAA 745 VE Q I A+TGDGVND+PALKKA+IG+AMG +G+ V+K A++M+L DDNF++IV Sbjct: 702 VEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTG 761 Query: 746 VEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATA 805 VEEGR I++N+K+ I Y ++SN+ E+ + P L V +L ++L TD +PA + Sbjct: 762 VEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAIS 821 Query: 806 LGFNPPDLDIMNKPPRNPK-EPLISGWLF-FRYLAIGCYVGAATVGAAAWWFIAADGGPR 863 L + + DIM + PRNPK + L++ L Y IG A G ++ I A+ G Sbjct: 822 LAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMI--QALGGFFTYFVILAENG-- 877 Query: 864 VSFYQLSHFLQCKEDNPD--FEGVDCAIFES---------PYPMTMALSVLVTIEMCNAL 912 + H L + D D V+ + + + A V + + L Sbjct: 878 ---FLPIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADL 934 Query: 913 NSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKI 972 ++ + +N L+ + +L + Y + + ++ PL T W Sbjct: 935 VICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCAFPY 994 Query: 973 SLPVILMDETLKFVAR 988 SL + + DE K + R Sbjct: 995 SLLIFVYDEVRKLIIR 1010 >gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapiens] Length = 992 Score = 357 bits (916), Expect = 3e-98 Identities = 299/1036 (28%), Positives = 481/1036 (46%), Gaps = 121/1036 (11%) Query: 5 HTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNEL-PAEEGKTLLELVIEQFEDLLVR 63 H +++E+ +G + S GL+ + ++ R G N L P ++ + F + Sbjct: 13 HKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSM- 71 Query: 64 ILLLAACISF----VLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEAL 119 +L + A + F + A EE + ++ V+ +++ +QE + +E+ Sbjct: 72 LLWIGAILCFLAYSIQAATEEEPQNDNLYLG-VVLSAVVIITGCFSYYQEAKSSKIMESF 130 Query: 120 KEYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSI 179 K P+ V R K I A+++V GD+VE+ GD++PAD+R+ I + +VD S Sbjct: 131 KNMVPQQALVIRNGEK--MSINAEEVVVGDLVEVKGGDRIPADLRI--ISANGCKVDNSS 186 Query: 180 LTGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEM 239 LTGES + D + + +N+ F TN G A G+VV TG T +G+I Sbjct: 187 LTGESEPQTRSPDFTNENPL---ETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLA 243 Query: 240 VATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIA 299 E +TP+ +++ F ++ V + ++ +I+++ + +W+ I+ Sbjct: 244 SGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSL------ILEYTWLEAVIFL---- 293 Query: 300 VALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTN 359 + + VA +PEGL A +T CL L +RMA+KN +V++L +VETLG TS ICSDKTGTLT N Sbjct: 294 IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQN 353 Query: 360 QMSVCRMFILDRV-EGDTCSLNE---FTITGSTYAPIGEVHKDDKPVNCHQYDGLVELAT 415 +M+V M+ +++ E DT F T +T+ + L+ Sbjct: 354 RMTVAHMWFDNQIHEADTTENQSGVSFDKTSATW---------------------LALSR 392 Query: 416 ICALCNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTELKGLSKIERANACN 472 I LCN + N+ K G+A+E+AL +E C Sbjct: 393 IAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIEL------------------CCG 434 Query: 473 SV--IKQLMKKEFTLEFSRDRK-SMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRV 529 SV +++ K + F+ K +S++ PN + + +KGAPE ++DRC+ I + Sbjct: 435 SVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHL--LVMKGAPERILDRCSSILL 492 Query: 530 GSTKVPMTSGVKQKIMSVIREWGS-GSDTLRCLALATHDNPLRREEMHLEDSANFIKYET 588 + P+ +K + E G G L L D D NF Sbjct: 493 HGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPI--D 550 Query: 589 NLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVT 648 NL FVG + M+DPPR V +V CR AGI+VIM+TGD+ TA AI + +GI + + Sbjct: 551 NLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETV 610 Query: 649 SK--AFTGREFDELNP-----------------SAQRDACLNARC---FARVEPSHKSKI 686 A ++NP S Q D L FAR P K I Sbjct: 611 EDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFARTSPQQKLII 670 Query: 687 VEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAA 745 VE Q I A+TGDGVND+PALKKA+IG+AMG +G+ V+K A++M+L DDNF++IV Sbjct: 671 VEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTG 730 Query: 746 VEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATA 805 VEEGR I++N+K+ I Y ++SN+ E+ + P L V +L ++L TD +PA + Sbjct: 731 VEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAIS 790 Query: 806 LGFNPPDLDIMNKPPRNPK-EPLISGWLF-FRYLAIGCYVGAATVGAAAWWFIAADGGPR 863 L + + DIM + PRNPK + L++ L Y IG A G ++ I A+ G Sbjct: 791 LAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMI--QALGGFFTYFVILAENG-- 846 Query: 864 VSFYQLSHFLQCKEDNPD--FEGVDCAIFES---------PYPMTMALSVLVTIEMCNAL 912 + H L + D D V+ + + + A V + + L Sbjct: 847 ---FLPIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADL 903 Query: 913 NSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKI 972 ++ + +N L+ + +L + Y + + ++ PL T W Sbjct: 904 VICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCAFPY 963 Query: 973 SLPVILMDETLKFVAR 988 SL + + DE K + R Sbjct: 964 SLLIFVYDEVRKLIIR 979 >gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens] Length = 1023 Score = 357 bits (916), Expect = 3e-98 Identities = 299/1036 (28%), Positives = 481/1036 (46%), Gaps = 121/1036 (11%) Query: 5 HTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNEL-PAEEGKTLLELVIEQFEDLLVR 63 H +++E+ +G + S GL+ + ++ R G N L P ++ + F + Sbjct: 44 HKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSM- 102 Query: 64 ILLLAACISF----VLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEAL 119 +L + A + F + A EE + ++ V+ +++ +QE + +E+ Sbjct: 103 LLWIGAILCFLAYSIQAATEEEPQNDNLYLG-VVLSAVVIITGCFSYYQEAKSSKIMESF 161 Query: 120 KEYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSI 179 K P+ V R K I A+++V GD+VE+ GD++PAD+R+ I + +VD S Sbjct: 162 KNMVPQQALVIRNGEK--MSINAEEVVVGDLVEVKGGDRIPADLRI--ISANGCKVDNSS 217 Query: 180 LTGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEM 239 LTGES + D + + +N+ F TN G A G+VV TG T +G+I Sbjct: 218 LTGESEPQTRSPDFTNENPL---ETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLA 274 Query: 240 VATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIA 299 E +TP+ +++ F ++ V + ++ +I+++ + +W+ I+ Sbjct: 275 SGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSL------ILEYTWLEAVIFL---- 324 Query: 300 VALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTN 359 + + VA +PEGL A +T CL L +RMA+KN +V++L +VETLG TS ICSDKTGTLT N Sbjct: 325 IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQN 384 Query: 360 QMSVCRMFILDRV-EGDTCSLNE---FTITGSTYAPIGEVHKDDKPVNCHQYDGLVELAT 415 +M+V M+ +++ E DT F T +T+ + L+ Sbjct: 385 RMTVAHMWFDNQIHEADTTENQSGVSFDKTSATW---------------------LALSR 423 Query: 416 ICALCNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTELKGLSKIERANACN 472 I LCN + N+ K G+A+E+AL +E C Sbjct: 424 IAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIEL------------------CCG 465 Query: 473 SV--IKQLMKKEFTLEFSRDRK-SMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRV 529 SV +++ K + F+ K +S++ PN + + +KGAPE ++DRC+ I + Sbjct: 466 SVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHL--LVMKGAPERILDRCSSILL 523 Query: 530 GSTKVPMTSGVKQKIMSVIREWGS-GSDTLRCLALATHDNPLRREEMHLEDSANFIKYET 588 + P+ +K + E G G L L D D NF Sbjct: 524 HGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPI--D 581 Query: 589 NLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVT 648 NL FVG + M+DPPR V +V CR AGI+VIM+TGD+ TA AI + +GI + + Sbjct: 582 NLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETV 641 Query: 649 SK--AFTGREFDELNP-----------------SAQRDACLNARC---FARVEPSHKSKI 686 A ++NP S Q D L FAR P K I Sbjct: 642 EDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFARTSPQQKLII 701 Query: 687 VEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAA 745 VE Q I A+TGDGVND+PALKKA+IG+AMG +G+ V+K A++M+L DDNF++IV Sbjct: 702 VEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTG 761 Query: 746 VEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATA 805 VEEGR I++N+K+ I Y ++SN+ E+ + P L V +L ++L TD +PA + Sbjct: 762 VEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAIS 821 Query: 806 LGFNPPDLDIMNKPPRNPK-EPLISGWLF-FRYLAIGCYVGAATVGAAAWWFIAADGGPR 863 L + + DIM + PRNPK + L++ L Y IG A G ++ I A+ G Sbjct: 822 LAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMI--QALGGFFTYFVILAENG-- 877 Query: 864 VSFYQLSHFLQCKEDNPD--FEGVDCAIFES---------PYPMTMALSVLVTIEMCNAL 912 + H L + D D V+ + + + A V + + L Sbjct: 878 ---FLPIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADL 934 Query: 913 NSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKI 972 ++ + +N L+ + +L + Y + + ++ PL T W Sbjct: 935 VICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCAFPY 994 Query: 973 SLPVILMDETLKFVAR 988 SL + + DE K + R Sbjct: 995 SLLIFVYDEVRKLIIR 1010 >gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens] Length = 1039 Score = 338 bits (866), Expect = 2e-92 Identities = 266/878 (30%), Positives = 427/878 (48%), Gaps = 105/878 (11%) Query: 5 HTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNEL-PAEEGKTLLELVIEQFE--DLL 61 H + E+ +G + GLS + +L R G N L P ++ +++ + + +L Sbjct: 59 HKLSNRELEEKYGTDIIMGLSSTRAAELLARDGPNSLTPPKQTPEIVKFLKQMVGGFSIL 118 Query: 62 VRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKE 121 + + I++ + + + ++ V+ L+++ I +QE + N + + + Sbjct: 119 LWVGAFLCWIAYGIQYSSDKSASLNNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNK 178 Query: 122 YEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSILT 181 P+ V R K I ++ +V GDIVE+ GD++PADIR+ S S RVD S LT Sbjct: 179 MIPQQALVIRDSEKKT--IPSEQLVVGDIVEVKGGDQIPADIRVLS--SQGCRVDNSSLT 234 Query: 182 GESV-----SVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIR 236 GES S H +P+ + KN+ F T G G+V+ TG T IG I Sbjct: 235 GESEPQPRSSEFTHENPL--------ETKNICFYSTTCLEGTVTGMVINTGDRTIIGHIA 286 Query: 237 DEMVATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYF 296 E+TP+ +++ F ++ V I I +II + + ++ G I Sbjct: 287 SLASGVGNEKTPIAIEIEHFVHIVAGVAVSIGILFFIIAVSLKYQVLDSIIFLIGII--- 343 Query: 297 KIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTL 356 VA +PEGL A +T L+L +RMAKKN +V++L +VETLG TS+ICSDKTGTL Sbjct: 344 -------VANVPEGLLATVTVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTL 396 Query: 357 TTNQMSVCRMFILDRV----EGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVE 412 T N+M+V ++ +++ + S F + T+A Sbjct: 397 TQNRMTVAHLWFDNQIFVADTSEDHSNQVFDQSSRTWA---------------------S 435 Query: 413 LATICALCNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTELKGLSKIERAN 469 L+ I LCN + + K +G+A+ETAL E + L + +I + N Sbjct: 436 LSKIITLCNRAEFKPGQENVPIMKKAVIGDASETALLKFSEVI------LGDVMEIRKRN 489 Query: 470 ACNSVIKQLMKKEFTLEFSRDRK-SMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIR 528 +K + F+ K +S++ + + + M +KGAPE ++++C+ I Sbjct: 490 ----------RKVAEIPFNSTNKFQLSIHEMDDPHGKRFL--MVMKGAPERILEKCSTIM 537 Query: 529 VGSTKVPMTSGVKQKIMSVIREWGS-GSDTLRCLALATHDNPLRREEMHLEDSANFIKYE 587 + + P+ + + E G G L L + D+ NF Sbjct: 538 INGEEHPLDKSTAKTFHTAYMELGGLGERVLGFCHLYLPADEFPETYSFDIDAMNFPT-- 595 Query: 588 TNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDE-- 645 +NL FVG + M+DPPR V +V CR AGI+VIM+TGD+ TA AI + +GI + Sbjct: 596 SNLCFVGLLSMIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANSET 655 Query: 646 ------------------DVTSKAFTGREFDELNPSAQRDACLNAR--CFARVEPSHKSK 685 D + TG E +++ + N + FAR P K Sbjct: 656 VEDIAHRLNIAVEQVNKRDAKAAVVTGMELKDMSSEQLDEILANYQEIVFARTSPQQKLI 715 Query: 686 IVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVA 744 IVE Q D + A+TGDGVND+PALKKA+IGIAMG +G+ AK A++MVL DDNF++IV Sbjct: 716 IVEGCQRQDAVVAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVT 775 Query: 745 AVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPAT 804 VEEGR I++N+K+ I Y ++ N+ E+ + +G P + + +L+++L TD +P+ Sbjct: 776 GVEEGRLIFDNLKKTIAYSLTKNIAELCPFLIYIIVGLPLPIGTITILFIDLGTDIIPSI 835 Query: 805 ALGFNPPDLDIMNKPPRNP-KEPLISGWL-FFRYLAIG 840 AL + + DIMN+ PR+ K+ L++ L + YL IG Sbjct: 836 ALAYEKAESDIMNRKPRHKNKDRLVNQPLAVYSYLHIG 873 >gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sapiens] Length = 1198 Score = 303 bits (776), Expect = 6e-82 Identities = 268/903 (29%), Positives = 412/903 (45%), Gaps = 150/903 (16%) Query: 29 VKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLAACISFVLAWF---------- 78 ++K K+ +G N +P ++ KT L+LV E +D+ + IL +AA IS L+++ Sbjct: 75 LEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLGLSFYHPPGEGNEGC 134 Query: 79 -------EEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGKVYR 131 E+ E ++E ILL ++ +V + + + E L+ + K Sbjct: 135 ATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTV 194 Query: 132 QDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSILTGESVSVIKHT 191 V +I +IV GDI ++ GD +PAD I+ L++D+S LTGES V K Sbjct: 195 VRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLF--IQGNDLKIDESSLTGESDQVRKSV 252 Query: 192 DPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIG------------------ 233 D P ML SGT++ G +V A GVN++ G Sbjct: 253 DKDP-----------MLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDK 301 Query: 234 --KIRDEMVATE----------------------QERTPLQQKLDEFGEQLSK---VISL 266 K +D A E +E++ LQ KL + Q+ K V+S Sbjct: 302 KAKQQDGAAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSA 361 Query: 267 ICIAVWIINIGHFNDPVHGGSW--------IRGAIYYFKIAVALAVAAIPEGLPAVITTC 318 I + + ++ V+ W ++ + +F I V + V A+PEGLP +T Sbjct: 362 ITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTIS 421 Query: 319 LALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDRVEGDTCS 378 LA ++M K N +VR L + ET+G + ICSDKTGTLTTN+M+V + ++ Sbjct: 422 LAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYV---------- 471 Query: 379 LNEFTITGSTYAPIGEVHKDDKP----VNCHQYDGLVELATICALCNDSALDYNEAKGVY 434 G+VH + P +N + L+ I + L + + Sbjct: 472 --------------GDVHYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGALP 517 Query: 435 EKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKKEFTLEFSRDRKSM 494 +VG TE L V + K + + + ++ + K +T F+ RKSM Sbjct: 518 RQVGNKTECGLLGFVLDL-----------KQDYEPVRSQMPEEKLYKVYT--FNSVRKSM 564 Query: 495 S-VYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIR--VGSTKVPMTSGVKQKIMSVIREW 551 S V P++ R M+ KGA E V+ +C I G +V + + VI Sbjct: 565 STVIKLPDESFR-----MYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPM 619 Query: 552 GSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLDPPRIEVASSVK 611 D LR + +A D P E D+ N I E LT + VG+ DP R EV +++ Sbjct: 620 AC--DGLRTICVAYRDFPSSPEPDW--DNENDILNE--LTCICVVGIEDPVRPEVPEAIR 673 Query: 612 LCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDED---VTSKAFTGR---EFDELNPSAQ 665 C++AGI V M+TGDN TA AI + GI ED + K F R E E+ Sbjct: 674 KCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERI 733 Query: 666 RDACLNARCFARVEPSHKSKIVEFLQSFD-----EITAMTGDGVNDAPALKKAEIGIAMG 720 R AR P+ K +V+ + ++ A+TGDG ND PALKKA++G AMG Sbjct: 734 DKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMG 793 Query: 721 -SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 779 +GT VAK AS+++L DDNFS+IV AV GR +Y+++ +F+++ ++ NV V+ F A Sbjct: 794 IAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGAC 853 Query: 780 LGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAI 839 + L VQ+LWVNL+ D + AL PP ++ + P +PLIS + L Sbjct: 854 ITQDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGH 913 Query: 840 GCY 842 Y Sbjct: 914 AVY 916 >gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sapiens] Length = 1170 Score = 295 bits (755), Expect = 2e-79 Identities = 302/1109 (27%), Positives = 481/1109 (43%), Gaps = 195/1109 (17%) Query: 3 NAHTKTVEEVLGHFGVNESTGLSLE--QVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 N H V+ + + GLS ++K ++ +G N +P ++ KT LELV E +D+ Sbjct: 45 NVHYGGVQNLCSRLKTSPVEGLSGNPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDV 104 Query: 61 LVRILLLAACISFVLAWF-----------------EEGEETITAFVEPFVILLILVANAI 103 + IL +AA IS VL+++ E+ E ++E IL ++ + Sbjct: 105 TLIILEIAAIISLVLSFYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVL 164 Query: 104 VGVWQERNAENAIEALK-EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPAD 162 V + + + E L+ E E ++ + +Q + +IV GDI ++ GD +PAD Sbjct: 165 VTAFNDWSKEKQFRGLQCRIEQEQKFSIIRNGQLIQ-LPVAEIVVGDIAQVKYGDLLPAD 223 Query: 163 IRLTSIKSTTLRVDQSILTGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGV 222 L I+ L++D+S LTGES V K D P ML SGT++ G V Sbjct: 224 GIL--IQGNDLKIDESSLTGESDHVKKSLDKDP-----------MLLSGTHVMEGSGRMV 270 Query: 223 VVATG--------------------------------------------------VNTEI 232 V A G +N++ Sbjct: 271 VTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQE 330 Query: 233 G-----KIRDEMVATEQERTPLQQKLDEFGEQLSK---VISLICIAVWIINIGHFNDPVH 284 G K + + ++E++ LQ KL Q+ K ++S + + + I+ N ++ Sbjct: 331 GIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVIN 390 Query: 285 GGSW--------IRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSL 336 W I+ + +F I + + V A+PEGLP +T LA ++M K N +VR L Sbjct: 391 RRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHL 450 Query: 337 PSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVH 396 + ET+G + ICSDKTGTLT N+M+V + +I G +H Sbjct: 451 DACETMGNATAICSDKTGTLTMNRMTVVQAYI------------------------GGIH 486 Query: 397 KDDKPVNC----HQYDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKM 452 P D +V +I + L + G+ +VG TE AL V Sbjct: 487 YRQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALLGFV--- 543 Query: 453 NVFDTELKGLSKIERANACNSVIKQLMKKEFTLEFSRDRKSMS-VYCTPNKPSRTSMSKM 511 T+LK + R N V ++ + K +T F+ RKSMS V PN R M Sbjct: 544 ----TDLKQDYQAVR----NEVPEEKLYKVYT--FNSVRKSMSTVIRNPNGGFR-----M 588 Query: 512 FVKGAPEGVIDRCTHI--RVGSTKVPMTSGVKQKIMSVIREWGSGSDTLRCLALATHDNP 569 + KGA E ++ +C I R G VP + + ++ + E D LR + +A D Sbjct: 589 YSKGASEIILRKCNRILDRKGEA-VPFKNKDRDDMVRTVIE-PMACDGLRTICIAYRDFD 646 Query: 570 LRREEMHLEDSANFIKYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKG 629 D+ N I T LT + VG+ DP R EV ++ C+QAGI V M+TGDN Sbjct: 647 DTEPSW---DNENEIL--TELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNIN 701 Query: 630 TAVAICRRIGIFGQDEDVTSKAFTGREFDELNPSAQRDA--------CLNARCFARVEPS 681 TA AI + GI +D G+EF+ L + + + R AR P+ Sbjct: 702 TARAIATKCGILTPGDDFL--CLEGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPT 759 Query: 682 HKSKIVEFL-----QSFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLA 735 K +V+ + ++ A+TGDG ND PALKKA++G AMG +GT VAK AS+++L Sbjct: 760 DKHTLVKGIIDSTVGEHRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILT 819 Query: 736 DDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVN 795 DDNF++IV AV GR +Y+++ +F+++ ++ NV V+ F A + L VQ+LWVN Sbjct: 820 DDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVN 879 Query: 796 LVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVGAATVGAAAWWF 855 L+ D + AL PP ++ + P +PLIS + L Y F Sbjct: 880 LIMDTFASLALATEPPTESLLKRRPYGRNKPLISRTMMKNILGHAFYQLIVI-------F 932 Query: 856 IAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMALSVLVTIEMCNALNSL 915 I G + F+ + + +P + T+ + V +++ N +NS Sbjct: 933 ILVFAGEK--FFDIDSGRKAPLHSPPSQ-----------HYTIVFNTFVLMQLFNEINSR 979 Query: 916 S-ENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISL 974 + + + NI + + I+ P F T L+++QWL L I + Sbjct: 980 KIHGEKNVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKP--FSCTSLSLSQWLWCLFIGI 1037 Query: 975 PVILMDETLKFVARNYLEPGKECVQPATK 1003 +L + + + L+ KE TK Sbjct: 1038 GELLWGQFISAIPTRSLKFLKEAGHGTTK 1066 >gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sapiens] Length = 1205 Score = 295 bits (755), Expect = 2e-79 Identities = 302/1109 (27%), Positives = 481/1109 (43%), Gaps = 195/1109 (17%) Query: 3 NAHTKTVEEVLGHFGVNESTGLSLE--QVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 N H V+ + + GLS ++K ++ +G N +P ++ KT LELV E +D+ Sbjct: 45 NVHYGGVQNLCSRLKTSPVEGLSGNPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDV 104 Query: 61 LVRILLLAACISFVLAWF-----------------EEGEETITAFVEPFVILLILVANAI 103 + IL +AA IS VL+++ E+ E ++E IL ++ + Sbjct: 105 TLIILEIAAIISLVLSFYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVL 164 Query: 104 VGVWQERNAENAIEALK-EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPAD 162 V + + + E L+ E E ++ + +Q + +IV GDI ++ GD +PAD Sbjct: 165 VTAFNDWSKEKQFRGLQCRIEQEQKFSIIRNGQLIQ-LPVAEIVVGDIAQVKYGDLLPAD 223 Query: 163 IRLTSIKSTTLRVDQSILTGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGV 222 L I+ L++D+S LTGES V K D P ML SGT++ G V Sbjct: 224 GIL--IQGNDLKIDESSLTGESDHVKKSLDKDP-----------MLLSGTHVMEGSGRMV 270 Query: 223 VVATG--------------------------------------------------VNTEI 232 V A G +N++ Sbjct: 271 VTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQE 330 Query: 233 G-----KIRDEMVATEQERTPLQQKLDEFGEQLSK---VISLICIAVWIINIGHFNDPVH 284 G K + + ++E++ LQ KL Q+ K ++S + + + I+ N ++ Sbjct: 331 GIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVIN 390 Query: 285 GGSW--------IRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSL 336 W I+ + +F I + + V A+PEGLP +T LA ++M K N +VR L Sbjct: 391 RRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHL 450 Query: 337 PSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVH 396 + ET+G + ICSDKTGTLT N+M+V + +I G +H Sbjct: 451 DACETMGNATAICSDKTGTLTMNRMTVVQAYI------------------------GGIH 486 Query: 397 KDDKPVNC----HQYDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKM 452 P D +V +I + L + G+ +VG TE AL V Sbjct: 487 YRQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALLGFV--- 543 Query: 453 NVFDTELKGLSKIERANACNSVIKQLMKKEFTLEFSRDRKSMS-VYCTPNKPSRTSMSKM 511 T+LK + R N V ++ + K +T F+ RKSMS V PN R M Sbjct: 544 ----TDLKQDYQAVR----NEVPEEKLYKVYT--FNSVRKSMSTVIRNPNGGFR-----M 588 Query: 512 FVKGAPEGVIDRCTHI--RVGSTKVPMTSGVKQKIMSVIREWGSGSDTLRCLALATHDNP 569 + KGA E ++ +C I R G VP + + ++ + E D LR + +A D Sbjct: 589 YSKGASEIILRKCNRILDRKGEA-VPFKNKDRDDMVRTVIE-PMACDGLRTICIAYRDFD 646 Query: 570 LRREEMHLEDSANFIKYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKG 629 D+ N I T LT + VG+ DP R EV ++ C+QAGI V M+TGDN Sbjct: 647 DTEPSW---DNENEIL--TELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNIN 701 Query: 630 TAVAICRRIGIFGQDEDVTSKAFTGREFDELNPSAQRDA--------CLNARCFARVEPS 681 TA AI + GI +D G+EF+ L + + + R AR P+ Sbjct: 702 TARAIATKCGILTPGDDFL--CLEGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPT 759 Query: 682 HKSKIVEFL-----QSFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLA 735 K +V+ + ++ A+TGDG ND PALKKA++G AMG +GT VAK AS+++L Sbjct: 760 DKHTLVKGIIDSTVGEHRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILT 819 Query: 736 DDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVN 795 DDNF++IV AV GR +Y+++ +F+++ ++ NV V+ F A + L VQ+LWVN Sbjct: 820 DDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVN 879 Query: 796 LVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVGAATVGAAAWWF 855 L+ D + AL PP ++ + P +PLIS + L Y F Sbjct: 880 LIMDTFASLALATEPPTESLLKRRPYGRNKPLISRTMMKNILGHAFYQLIVI-------F 932 Query: 856 IAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMALSVLVTIEMCNALNSL 915 I G + F+ + + +P + T+ + V +++ N +NS Sbjct: 933 ILVFAGEK--FFDIDSGRKAPLHSPPSQ-----------HYTIVFNTFVLMQLFNEINSR 979 Query: 916 S-ENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISL 974 + + + NI + + I+ P F T L+++QWL L I + Sbjct: 980 KIHGEKNVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKP--FSCTSLSLSQWLWCLFIGI 1037 Query: 975 PVILMDETLKFVARNYLEPGKECVQPATK 1003 +L + + + L+ KE TK Sbjct: 1038 GELLWGQFISAIPTRSLKFLKEAGHGTTK 1066 >gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sapiens] Length = 1176 Score = 289 bits (740), Expect = 8e-78 Identities = 266/902 (29%), Positives = 410/902 (45%), Gaps = 135/902 (14%) Query: 19 NESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLAACISFVLAWF 78 NE + +++ + +G N +P ++ KT L+LV E +D+ + IL +AA +S L+++ Sbjct: 68 NEGLSGNPADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIVSLGLSFY 127 Query: 79 E--EGEETI--------------TAFVEPFVILLILVANAIVGVWQERNAENAIEALKEY 122 + EG+ + T ++E ILL +V +V + + + E L+ Sbjct: 128 QPPEGDNALCGEVSVGEEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQFRGLQSR 187 Query: 123 EPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSILTG 182 + K V +I DI GDI ++ GD +PAD L I+ L++D+S LTG Sbjct: 188 IEQEQKFTVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGIL--IQGNDLKIDESSLTG 245 Query: 183 ESVSVIKHTDPVP-----------DPRAV------------------------------N 201 ES V K D P R V Sbjct: 246 ESDHVKKSLDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDEKK 305 Query: 202 QDKKNMLFSGT-------NIAAGKAMGVVVATGVNTEIGKIRDEMVAT--EQERTPLQQK 252 ++KKN G G AM + G +D+ A ++E++ LQ K Sbjct: 306 KEKKNKKQDGAIENRNKAKAQDGAAMEMQPLKSEEGGDGDEKDKKKANLPKKEKSVLQGK 365 Query: 253 LDEFGEQLSKVISLICIAVWIINIGHFNDP---VHGGSW--------IRGAIYYFKIAVA 301 L + Q+ K L+ II + +F V W I+ + +F I V Sbjct: 366 LTKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKFFIIGVT 425 Query: 302 LAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361 + V A+PEGLP +T LA ++M K N +VR L + ET+G + ICSDKTGTLT N+M Sbjct: 426 VLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRM 485 Query: 362 SVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCN 421 +V + +I ++ Y + E + P N Y LV ++ Sbjct: 486 TVVQAYINEK----------------HYKKVPE--PEAIPPNILSY--LVTGISVNCAYT 525 Query: 422 DSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKK 481 L + G+ VG TE AL L+ + K + + N + ++ + K Sbjct: 526 SKILPPEKEGGLPRHVGNKTECALLGLLLDL-----------KRDYQDVRNEIPEEALYK 574 Query: 482 EFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRV--GSTKVPMTSG 539 +T F+ RKSMS + S ++F KGA E ++ +C I G KV Sbjct: 575 VYT--FNSVRKSMSTVLKNSDGSY----RIFSKGASEIILKKCFKILSANGEAKVFRPRD 628 Query: 540 VKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGML 599 + +VI S + LR + LA D P E ++ + + T LT + VG+ Sbjct: 629 RDDIVKTVIEPMAS--EGLRTICLAFRDFPAGEPEPEWDNENDIV---TGLTCIAVVGIE 683 Query: 600 DPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDED---VTSKAFTGR- 655 DP R EV ++K C++AGI V M+TGDN TA AI + GI ED + K F R Sbjct: 684 DPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGILHPGEDFLCLEGKDFNRRI 743 Query: 656 --EFDELNPSAQRDACLNARCFARVEPSHKSKIVEFL-----QSFDEITAMTGDGVNDAP 708 E E+ R AR P+ K +V+ + ++ A+TGDG ND P Sbjct: 744 RNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTVSDQRQVVAVTGDGTNDGP 803 Query: 709 ALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSN 767 ALKKA++G AMG +GT VAK AS+++L DDNF++IV AV GR +Y+++ +F+++ ++ N Sbjct: 804 ALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVN 863 Query: 768 VGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPL 827 V V+ F A + L VQ+LWVNL+ D L + AL PP ++ + P +PL Sbjct: 864 VVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTESLLLRKPYGRNKPL 923 Query: 828 IS 829 IS Sbjct: 924 IS 925 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.135 0.404 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 38,039,412 Number of Sequences: 37866 Number of extensions: 1655779 Number of successful extensions: 4259 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 59 Number of HSP's successfully gapped in prelim test: 7 Number of HSP's that attempted gapping in prelim test: 3918 Number of HSP's gapped (non-prelim): 150 length of query: 1042 length of database: 18,247,518 effective HSP length: 112 effective length of query: 930 effective length of database: 14,006,526 effective search space: 13026069180 effective search space used: 13026069180 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.