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Search of human proteins with 24308514
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24308514 glutathione S-transferase alpha 5 [Homo sapiens]
(222 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24308514 glutathione S-transferase alpha 5 [Homo sapiens] 436 e-123
gi|22091454 glutathione S-transferase alpha 1 [Homo sapiens] 393 e-110
gi|215276987 glutathione S-transferase alpha 2 [Homo sapiens] 386 e-108
gi|24430144 glutathione S-transferase alpha 3 [Homo sapiens] 374 e-104
gi|113417526 PREDICTED: similar to glutathione S-transferase alp... 257 5e-69
gi|169169045 PREDICTED: similar to glutathione S-transferase alp... 256 1e-68
gi|113418092 PREDICTED: similar to glutathione S-transferase alp... 256 1e-68
gi|4504173 glutathione S-transferase alpha 4 [Homo sapiens] 248 3e-66
gi|4504183 glutathione transferase [Homo sapiens] 82 3e-16
gi|7657457 prostaglandin-D synthase [Homo sapiens] 70 1e-12
gi|4504175 glutathione S-transferase mu 2 isoform 1 [Homo sapiens] 66 2e-11
gi|23065552 glutathione S-transferase mu 3 [Homo sapiens] 65 5e-11
gi|215277000 glutathione S-transferase mu 2 isoform 2 [Homo sapi... 63 2e-10
gi|23065544 glutathione S-transferase mu 1 isoform 1 [Homo sapiens] 59 4e-09
gi|4504179 glutathione S-transferase mu 4 isoform 1 [Homo sapiens] 54 8e-08
gi|23065563 glutathione S-transferase mu 5 [Homo sapiens] 53 2e-07
gi|23065557 glutathione S-transferase mu 4 isoform 2 [Homo sapiens] 50 1e-06
gi|23065547 glutathione S-transferase mu 1 isoform 2 [Homo sapiens] 46 3e-05
gi|22202624 glutathione transferase zeta 1 isoform 1 [Homo sapiens] 46 3e-05
gi|22202622 glutathione transferase zeta 1 isoform 3 [Homo sapiens] 44 1e-04
gi|15011844 selenophosphate synthetase 2 [Homo sapiens] 32 0.56
gi|160948599 integrator complex subunit 1 [Homo sapiens] 31 0.96
gi|19913398 smoothelin isoform a [Homo sapiens] 30 1.6
gi|44955921 ELK3 protein [Homo sapiens] 29 2.8
gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens] 29 2.8
gi|24797148 selenophosphate synthetase 1 [Homo sapiens] 29 2.8
gi|109255234 centrosomal protein 290kDa [Homo sapiens] 29 3.7
gi|41281453 serine/threonine kinase 2 [Homo sapiens] 29 3.7
gi|167466164 glutathione S-transferase theta 1 [Homo sapiens] 28 4.8
gi|33620755 YEATS domain containing 2 [Homo sapiens] 28 4.8
>gi|24308514 glutathione S-transferase alpha 5 [Homo sapiens]
Length = 222
Score = 436 bits (1121), Expect = e-123
Identities = 222/222 (100%), Positives = 222/222 (100%)
Query: 1 MAEKPKLHYSNARGSMESIRWLLAAAGVELEEKFLESAEDLDKLRNDGSLLFQQVPMVEI 60
MAEKPKLHYSNARGSMESIRWLLAAAGVELEEKFLESAEDLDKLRNDGSLLFQQVPMVEI
Sbjct: 1 MAEKPKLHYSNARGSMESIRWLLAAAGVELEEKFLESAEDLDKLRNDGSLLFQQVPMVEI 60
Query: 61 DGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDAK 120
DGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDAK
Sbjct: 61 DGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDAK 120
Query: 121 TALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPL 180
TALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPL
Sbjct: 121 TALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPL 180
Query: 181 LKALKTRISNLPTVKKFLQPGSQRKPPMDEKSLEEARKIFRF 222
LKALKTRISNLPTVKKFLQPGSQRKPPMDEKSLEEARKIFRF
Sbjct: 181 LKALKTRISNLPTVKKFLQPGSQRKPPMDEKSLEEARKIFRF 222
>gi|22091454 glutathione S-transferase alpha 1 [Homo sapiens]
Length = 222
Score = 393 bits (1009), Expect = e-110
Identities = 200/222 (90%), Positives = 207/222 (93%)
Query: 1 MAEKPKLHYSNARGSMESIRWLLAAAGVELEEKFLESAEDLDKLRNDGSLLFQQVPMVEI 60
MAEKPKLHY NARG MES RWLLAAAGVE EEKF++SAEDLDKLRNDG L+FQQVPMVEI
Sbjct: 1 MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60
Query: 61 DGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDAK 120
DGMKLVQTRAILNYIASKYNLYGKD+KERALIDMY EGI DL EMILLL +C PEE+DAK
Sbjct: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAK 120
Query: 121 TALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPL 180
AL+KEKIKNRYFPAFEKVLKSH QDYLVGNKLS ADIHLVEL YYVEELDSSLISSFPL
Sbjct: 121 LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180
Query: 181 LKALKTRISNLPTVKKFLQPGSQRKPPMDEKSLEEARKIFRF 222
LKALKTRISNLPTVKKFLQPGS RKPPMDEKSLEEARKIFRF
Sbjct: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFRF 222
>gi|215276987 glutathione S-transferase alpha 2 [Homo sapiens]
Length = 222
Score = 386 bits (992), Expect = e-108
Identities = 197/222 (88%), Positives = 206/222 (92%)
Query: 1 MAEKPKLHYSNARGSMESIRWLLAAAGVELEEKFLESAEDLDKLRNDGSLLFQQVPMVEI 60
MAEKPKLHYSN RG MESIRWLLAAAGVE EEKF++SAEDLDKLRNDG L+FQQVPMVEI
Sbjct: 1 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60
Query: 61 DGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDAK 120
DGMKLVQTRAILNYIASKYNLYGKD+KE+ALIDMY EGI DL EMILLL QPEE+DAK
Sbjct: 61 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK 120
Query: 121 TALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPL 180
AL++EK KNRYFPAFEKVLKSH QDYLVGNKLS ADIHLVEL YYVEELDSSLISSFPL
Sbjct: 121 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180
Query: 181 LKALKTRISNLPTVKKFLQPGSQRKPPMDEKSLEEARKIFRF 222
LKALKTRISNLPTVKKFLQPGS RKPPMDEKSLEE+RKIFRF
Sbjct: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF 222
>gi|24430144 glutathione S-transferase alpha 3 [Homo sapiens]
Length = 222
Score = 374 bits (959), Expect = e-104
Identities = 190/222 (85%), Positives = 202/222 (90%)
Query: 1 MAEKPKLHYSNARGSMESIRWLLAAAGVELEEKFLESAEDLDKLRNDGSLLFQQVPMVEI 60
MA KPKLHY N RG ME IRWLLAAAGVE EEKF+ SAEDL KLRNDGSL+FQQVPMVEI
Sbjct: 1 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI 60
Query: 61 DGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDAK 120
DGMKLVQTRAILNYIASKYNLYGKD+KERALIDMYTEG+ DL EMILLL +C+PEE+DAK
Sbjct: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120
Query: 121 TALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPL 180
AL+KEK K+RYFPAFEKVL+SH QDYLVGNKLS ADI LVEL YYVEELDSSLIS+FPL
Sbjct: 121 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180
Query: 181 LKALKTRISNLPTVKKFLQPGSQRKPPMDEKSLEEARKIFRF 222
LKALKTRISNLPTVKKFLQPGS RKPP D K+LEEARKIFRF
Sbjct: 181 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF 222
>gi|113417526 PREDICTED: similar to glutathione S-transferase alpha
3 [Homo sapiens]
Length = 216
Score = 257 bits (657), Expect = 5e-69
Identities = 140/210 (66%), Positives = 159/210 (75%), Gaps = 16/210 (7%)
Query: 28 VELEEKFLESAEDLDKLRNDGSLLFQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDMK 87
VE E KFLESA+DL+KLRND S +FQQVPMVEIDGMKLVQTRAILNYIASKYNL GKD+K
Sbjct: 6 VESERKFLESAKDLEKLRNDESFMFQQVPMVEIDGMKLVQTRAILNYIASKYNLCGKDIK 65
Query: 88 ERA---------LIDMYTEGIVDLTEMILLLLICQPEERDAKTALVKEKIKNRYFPAFEK 138
ERA +DMY EG L+E +L + PEE+DAK AL+KE + YFP FE
Sbjct: 66 ERAPYIWLFLSYRVDMYIEGRAGLSEKLLHCSLHPPEEKDAKLALIKEGTTSHYFPVFET 125
Query: 139 VLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPLLK-------ALKTRISNL 191
VLKSH QDY +GNKLS ADIHLV+L Y+VEE DSSLIS+FP+LK ALK RIS L
Sbjct: 126 VLKSHEQDYFIGNKLSQADIHLVKLLYHVEEPDSSLISNFPVLKAVLCALRALKIRISKL 185
Query: 192 PTVKKFLQPGSQRKPPMDEKSLEEARKIFR 221
PTVKKFLQPGS RK P+D K L+EA KIF+
Sbjct: 186 PTVKKFLQPGSLRKLPIDAKGLQEATKIFK 215
>gi|169169045 PREDICTED: similar to glutathione S-transferase alpha
3 [Homo sapiens]
Length = 227
Score = 256 bits (653), Expect = 1e-68
Identities = 139/209 (66%), Positives = 158/209 (75%), Gaps = 16/209 (7%)
Query: 29 ELEEKFLESAEDLDKLRNDGSLLFQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDMKE 88
E E KFLESA+DL+KLRND S +FQQVPMVEIDGMKLVQTRAILNYI SKYNL GKD+KE
Sbjct: 18 ESERKFLESAKDLEKLRNDESFMFQQVPMVEIDGMKLVQTRAILNYIVSKYNLCGKDIKE 77
Query: 89 RA---------LIDMYTEGIVDLTEMILLLLICQPEERDAKTALVKEKIKNRYFPAFEKV 139
RA +DMY EG L+E +L + PEE+DAK AL+KE + YFP FE V
Sbjct: 78 RAPYIWLFLSYRVDMYIEGRAGLSEKLLHCSLHPPEEKDAKLALIKEGTTSHYFPVFETV 137
Query: 140 LKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPLLK-------ALKTRISNLP 192
LKSH QDYL+GNKLS ADIHLV+L Y+VEE DSSLIS+FP+LK ALK RIS LP
Sbjct: 138 LKSHEQDYLIGNKLSQADIHLVKLLYHVEEPDSSLISNFPVLKAVLCALRALKIRISKLP 197
Query: 193 TVKKFLQPGSQRKPPMDEKSLEEARKIFR 221
TVKKFLQPGS RK P+D K L+EA KIF+
Sbjct: 198 TVKKFLQPGSLRKLPIDAKGLQEATKIFK 226
>gi|113418092 PREDICTED: similar to glutathione S-transferase alpha
3 [Homo sapiens]
Length = 216
Score = 256 bits (653), Expect = 1e-68
Identities = 139/210 (66%), Positives = 158/210 (75%), Gaps = 16/210 (7%)
Query: 28 VELEEKFLESAEDLDKLRNDGSLLFQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDMK 87
VE E KFLESA+DL+KLRND S +FQQVPMVEIDGMKLVQTRAILNYI SKYNL GKD+K
Sbjct: 6 VESERKFLESAKDLEKLRNDESFMFQQVPMVEIDGMKLVQTRAILNYIVSKYNLCGKDIK 65
Query: 88 ERA---------LIDMYTEGIVDLTEMILLLLICQPEERDAKTALVKEKIKNRYFPAFEK 138
ERA +DMY EG L+E +L + PEE+DAK AL+KE + YFP FE
Sbjct: 66 ERAPYIWLFLSYRVDMYIEGRAGLSEKLLHCSLHPPEEKDAKLALIKEGTTSHYFPVFET 125
Query: 139 VLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPLLK-------ALKTRISNL 191
VLKSH QDY +GNKLS ADIHLV+L Y+VEE DSSLIS+FP+LK ALK RIS L
Sbjct: 126 VLKSHEQDYFIGNKLSQADIHLVKLLYHVEEPDSSLISNFPVLKAVLCALRALKIRISKL 185
Query: 192 PTVKKFLQPGSQRKPPMDEKSLEEARKIFR 221
PTVKKFLQPGS RK P+D K L+EA KIF+
Sbjct: 186 PTVKKFLQPGSLRKLPIDAKGLQEATKIFK 215
>gi|4504173 glutathione S-transferase alpha 4 [Homo sapiens]
Length = 222
Score = 248 bits (633), Expect = 3e-66
Identities = 118/221 (53%), Positives = 166/221 (75%)
Query: 1 MAEKPKLHYSNARGSMESIRWLLAAAGVELEEKFLESAEDLDKLRNDGSLLFQQVPMVEI 60
MA +PKLHY N RG MES+RW+LAAAGVE +E+FLE+ E L KL++ LLFQQVPMVEI
Sbjct: 1 MAARPKLHYPNGRGRMESVRWVLAAAGVEFDEEFLETKEQLYKLQDGNHLLFQQVPMVEI 60
Query: 61 DGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDAK 120
DGMKLVQTR+IL+YIA K+NL+GK++KER LIDMY EG +DL E++++ +P+++ +
Sbjct: 61 DGMKLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKE 120
Query: 121 TALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPL 180
+ +K RYFP FEK+L+ H Q +LVGN+LS AD+ L++ +EE +++S+FP
Sbjct: 121 VVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPF 180
Query: 181 LKALKTRISNLPTVKKFLQPGSQRKPPMDEKSLEEARKIFR 221
L+ ++SN+PT+K+FL+PGS++KPP DE + IFR
Sbjct: 181 LQEYTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFR 221
>gi|4504183 glutathione transferase [Homo sapiens]
Length = 210
Score = 82.4 bits (202), Expect = 3e-16
Identities = 58/193 (30%), Positives = 99/193 (51%), Gaps = 9/193 (4%)
Query: 9 YSNARGSMESIRWLLAAAGVELEEKFLESAEDLDKLRNDGSLLFQQVPMVEIDGMKLVQT 68
Y RG ++R LLA G +E+ + + E + S L+ Q+P + + L Q+
Sbjct: 8 YFPVRGRCAALRMLLADQGQSWKEEVV-TVETWQEGSLKASCLYGQLPKFQDGDLTLYQS 66
Query: 69 RAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEE-RDAKTALVKEK 127
IL ++ LYGKD +E AL+DM +G+ DL + L+ E +D + +
Sbjct: 67 NTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYTNYEAGKDDYVKALPGQ 126
Query: 128 IKNRYFPAFEKVLKSHR--QDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPLLKALK 185
+K FE +L ++ + ++VG+++S+AD +L++L E L + +FPLL A
Sbjct: 127 LK-----PFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDAFPLLSAYV 181
Query: 186 TRISNLPTVKKFL 198
R+S P +K FL
Sbjct: 182 GRLSARPKLKAFL 194
>gi|7657457 prostaglandin-D synthase [Homo sapiens]
Length = 199
Score = 70.5 bits (171), Expect = 1e-12
Identities = 51/202 (25%), Positives = 100/202 (49%), Gaps = 10/202 (4%)
Query: 6 KLHYSNARGSMESIRWLLAAAGVELEEKFLESAEDLDKLRNDGSLLFQQVPMVEIDGMKL 65
KL Y N RG E IR++ A ++ E+ +E A D ++++ +L F ++P++E+DG+ L
Sbjct: 5 KLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQA-DWPEIKS--TLPFGKIPILEVDGLTL 61
Query: 66 VQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDAKTALVK 125
Q+ AI Y+ +L G E+ +D IVD + + +++D K +
Sbjct: 62 HQSLAIARYLTKNTDLAGNTEMEQCHVD----AIVDTLDDFMSCFPWAEKKQDVKEQMFN 117
Query: 126 EKIKNRYFPAFEKVLKSH--RQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPLLKA 183
E + P + L ++ +++L+GN ++WAD + + L+ + P L
Sbjct: 118 ELLTYN-APHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPRLVT 176
Query: 184 LKTRISNLPTVKKFLQPGSQRK 205
L+ ++ +P V +++ Q K
Sbjct: 177 LRKKVQAIPAVANWIKRRPQTK 198
>gi|4504175 glutathione S-transferase mu 2 isoform 1 [Homo sapiens]
Length = 218
Score = 66.2 bits (160), Expect = 2e-11
Identities = 61/206 (29%), Positives = 98/206 (47%), Gaps = 24/206 (11%)
Query: 7 LHYSNARGSMESIRWLLAAAGVELEEK--FLESAEDLDKLR--NDGSLL---FQQVPMVE 59
L Y N RG SIR LL EEK + A D D+ + N+ L F +P +
Sbjct: 5 LGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 63
Query: 60 IDGM-KLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERD 118
IDG K+ Q+ AIL YIA K+NL G+ KE+ D+ +D + M L L P+
Sbjct: 64 IDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMD-SRMQLAKLCYDPD--- 119
Query: 119 AKTALVKEKIKNRYFPAFEKVLKSH-----RQDYLVGNKLSWADIHLVELFYYVEELDSS 173
EK+K Y A ++LK + +Q + +G+K+++ D ++ + + S
Sbjct: 120 ------FEKLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPS 173
Query: 174 LISSFPLLKALKTRISNLPTVKKFLQ 199
+ +FP LK +R L + +++
Sbjct: 174 CLDAFPNLKDFISRFEGLEKISAYMK 199
>gi|23065552 glutathione S-transferase mu 3 [Homo sapiens]
Length = 225
Score = 65.1 bits (157), Expect = 5e-11
Identities = 57/224 (25%), Positives = 90/224 (40%), Gaps = 22/224 (9%)
Query: 7 LHYSNARGSMESIRWLLAAAGVELEEKFLESAEDLDKLRNDG-------SLLFQQVPMVE 59
L Y + RG +IR LL EEK E D R+ L F +P +
Sbjct: 9 LGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLL 68
Query: 60 IDGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDA 119
K+ Q+ AIL YIA K+N+ G+ +E+ +D+ ++D L+ +C +
Sbjct: 69 DGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQ--LIRLCYSSDH-- 124
Query: 120 KTALVKEKIKNRYFPAFEKVLKSH-----RQDYLVGNKLSWADIHLVELFYYVEELDSSL 174
EK+K +Y LK + + G KL++ D ++ D
Sbjct: 125 ------EKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKC 178
Query: 175 ISSFPLLKALKTRISNLPTVKKFLQPGSQRKPPMDEKSLEEARK 218
+ FP LKA R L + +LQ K P++ K + K
Sbjct: 179 LDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 222
>gi|215277000 glutathione S-transferase mu 2 isoform 2 [Homo
sapiens]
Length = 191
Score = 62.8 bits (151), Expect = 2e-10
Identities = 60/197 (30%), Positives = 94/197 (47%), Gaps = 24/197 (12%)
Query: 7 LHYSNARGSMESIRWLLAAAGVELEEK--FLESAEDLDKLR--NDGSLL---FQQVPMVE 59
L Y N RG SIR LL EEK + A D D+ + N+ L F +P +
Sbjct: 5 LGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 63
Query: 60 IDGM-KLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERD 118
IDG K+ Q+ AIL YIA K+NL G+ KE+ D+ +D + M L L P+
Sbjct: 64 IDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMD-SRMQLAKLCYDPD--- 119
Query: 119 AKTALVKEKIKNRYFPAFEKVLKSH-----RQDYLVGNKLSWADIHLVELFYYVEELDSS 173
EK+K Y A ++LK + +Q + +G+K+++ D ++ + + S
Sbjct: 120 ------FEKLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPS 173
Query: 174 LISSFPLLKALKTRISN 190
+ +FP LK +R +
Sbjct: 174 CLDAFPNLKDFISRFEH 190
>gi|23065544 glutathione S-transferase mu 1 isoform 1 [Homo sapiens]
Length = 218
Score = 58.5 bits (140), Expect = 4e-09
Identities = 53/205 (25%), Positives = 93/205 (45%), Gaps = 22/205 (10%)
Query: 7 LHYSNARGSMESIRWLLAAAGVELEEK--FLESAEDLDKLR--NDGSLL---FQQVPMVE 59
L Y + RG +IR LL EEK + A D D+ + N+ L F +P +
Sbjct: 5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64
Query: 60 IDGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDA 119
K+ Q+ AIL YIA K+NL G+ +E+ +D+ +D M L ++ PE
Sbjct: 65 DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMD-NHMQLGMICYNPE---- 119
Query: 120 KTALVKEKIKNRYFPAFEKVLKSH-----RQDYLVGNKLSWADIHLVELFYYVEELDSSL 174
EK+K +Y + LK + ++ + GNK+++ D + ++ +
Sbjct: 120 -----FEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKC 174
Query: 175 ISSFPLLKALKTRISNLPTVKKFLQ 199
+ +FP LK +R L + +++
Sbjct: 175 LDAFPNLKDFISRFEGLEKISAYMK 199
>gi|4504179 glutathione S-transferase mu 4 isoform 1 [Homo sapiens]
Length = 218
Score = 54.3 bits (129), Expect = 8e-08
Identities = 50/205 (24%), Positives = 91/205 (44%), Gaps = 22/205 (10%)
Query: 7 LHYSNARGSMESIRWLLAAAGVELEEK--FLESAEDLDKLR--NDGSLL---FQQVPMVE 59
L Y + RG +IR LL EEK + A D D+ + N+ L F +P +
Sbjct: 5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64
Query: 60 IDGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDA 119
K+ Q+ AIL YIA K+NL G+ +E+ +D+ +D++ L +C +
Sbjct: 65 DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQ--LARVCYSPD--- 119
Query: 120 KTALVKEKIKNRYFPAFEKVLKSHRQ-----DYLVGNKLSWADIHLVELFYYVEELDSSL 174
EK+K Y +++ Q + VG+K+++ D ++ + +
Sbjct: 120 -----FEKLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNC 174
Query: 175 ISSFPLLKALKTRISNLPTVKKFLQ 199
+ +FP LK +R L + +++
Sbjct: 175 LDAFPNLKDFISRFEGLEKISAYMK 199
>gi|23065563 glutathione S-transferase mu 5 [Homo sapiens]
Length = 218
Score = 53.1 bits (126), Expect = 2e-07
Identities = 51/205 (24%), Positives = 91/205 (44%), Gaps = 22/205 (10%)
Query: 7 LHYSNARGSMESIRWLLAAAGVELEEK--FLESAEDLDKLR--NDGSLL---FQQVPMVE 59
L Y + RG +IR LL EK L A D D+ + N+ L F +P +
Sbjct: 5 LGYWDIRGLAHAIRLLLEYTDSSYVEKKYTLGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64
Query: 60 IDGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDA 119
K+ Q+ AIL YIA K+NL G+ +E+ +D+ ++D M L+ L P+
Sbjct: 65 DGAHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQVMD-NHMELVRLCYDPD---- 119
Query: 120 KTALVKEKIKNRYFPAFEKVLKSH-----RQDYLVGNKLSWADIHLVELFYYVEELDSSL 174
EK+K +Y + LK + ++ + G+K+++ D ++ +
Sbjct: 120 -----FEKLKPKYLEELPEKLKLYSEFLGKRPWFAGDKITFVDFLAYDVLDMKRIFEPKC 174
Query: 175 ISSFPLLKALKTRISNLPTVKKFLQ 199
+ +F LK +R L + +++
Sbjct: 175 LDAFLNLKDFISRFEGLKKISAYMK 199
>gi|23065557 glutathione S-transferase mu 4 isoform 2 [Homo sapiens]
Length = 195
Score = 50.4 bits (119), Expect = 1e-06
Identities = 49/193 (25%), Positives = 86/193 (44%), Gaps = 22/193 (11%)
Query: 7 LHYSNARGSMESIRWLLAAAGVELEEK--FLESAEDLDKLR--NDGSLL---FQQVPMVE 59
L Y + RG +IR LL EEK + A D D+ + N+ L F +P +
Sbjct: 5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64
Query: 60 IDGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDA 119
K+ Q+ AIL YIA K+NL G+ +E+ +D+ +D++ L +C +
Sbjct: 65 DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQ--LARVCYSPD--- 119
Query: 120 KTALVKEKIKNRYFPAFEKVLKSHRQ-----DYLVGNKLSWADIHLVELFYYVEELDSSL 174
EK+K Y +++ Q + VG+K+++ D ++ + +
Sbjct: 120 -----FEKLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNC 174
Query: 175 ISSFPLLKALKTR 187
+ +FP LK +R
Sbjct: 175 LDAFPNLKDFISR 187
>gi|23065547 glutathione S-transferase mu 1 isoform 2 [Homo sapiens]
Length = 181
Score = 45.8 bits (107), Expect = 3e-05
Identities = 46/158 (29%), Positives = 72/158 (45%), Gaps = 22/158 (13%)
Query: 7 LHYSNARGSMESIRWLLAAAGVELEEK--FLESAEDLDKLR--NDGSLL---FQQVPMVE 59
L Y + RG +IR LL EEK + A D D+ + N+ L F +P +
Sbjct: 5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64
Query: 60 IDGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDA 119
K+ Q+ AIL YIA K+NL G+ +E+ +D+ +D M L ++ PE
Sbjct: 65 DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMD-NHMQLGMICYNPE---- 119
Query: 120 KTALVKEKIKNRYFPAFEKVLKSH-----RQDYLVGNK 152
EK+K +Y + LK + ++ + GNK
Sbjct: 120 -----FEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNK 152
>gi|22202624 glutathione transferase zeta 1 isoform 1 [Homo sapiens]
Length = 216
Score = 45.8 bits (107), Expect = 3e-05
Identities = 51/194 (26%), Positives = 91/194 (46%), Gaps = 10/194 (5%)
Query: 2 AEKPKLHYSNARGSME-SIRWLLAAAGVELEEKFLESAEDL-DKLRNDGSLL--FQQVPM 57
A KP L YS R S +R LA G++ E + +D + D L +QVP
Sbjct: 3 AGKPIL-YSYFRSSCSWRVRIALALKGIDYETVPINLIKDGGQQFSKDFQALNPMKQVPT 61
Query: 58 VEIDGMKLVQTRAILNYIASKY---NLYGKDMKERALIDMYTEGIVDLTEMILLLLICQP 114
++IDG+ + Q+ AI+ Y+ L +D K+RA + M ++ I + + L + +
Sbjct: 62 LKIDGITIHQSLAIIEYLEEMRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQNLSVLKQ 121
Query: 115 EERDAKTALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSL 174
+ + + I F A E++L+S Y VG++++ AD+ LV E L
Sbjct: 122 VGEEMQLTWAQNAI-TCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAERFKVDL 180
Query: 175 ISSFPLLKALKTRI 188
+ +P + ++ R+
Sbjct: 181 -TPYPTISSINKRL 193
>gi|22202622 glutathione transferase zeta 1 isoform 3 [Homo sapiens]
Length = 161
Score = 43.5 bits (101), Expect = 1e-04
Identities = 35/139 (25%), Positives = 69/139 (49%), Gaps = 5/139 (3%)
Query: 53 QQVPMVEIDGMKLVQTRAILNYIASKY---NLYGKDMKERALIDMYTEGIVDLTEMILLL 109
+QVP ++IDG+ + Q+ AI+ Y+ L +D K+RA + M ++ I + + L
Sbjct: 2 KQVPTLKIDGITIHQSLAIIEYLEEMRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQNL 61
Query: 110 LICQPEERDAKTALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHLVELFYYVEE 169
+ + + + + I F A E++L+S Y VG++++ AD+ LV E
Sbjct: 62 SVLKQVGEEMQLTWAQNAI-TCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAER 120
Query: 170 LDSSLISSFPLLKALKTRI 188
L + +P + ++ R+
Sbjct: 121 FKVDL-TPYPTISSINKRL 138
>gi|15011844 selenophosphate synthetase 2 [Homo sapiens]
Length = 448
Score = 31.6 bits (70), Expect = 0.56
Identities = 20/66 (30%), Positives = 31/66 (46%), Gaps = 3/66 (4%)
Query: 62 GMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQ---PEERD 118
G+ LVQT + + G+ L D+Y GI + M++LL + Q EER+
Sbjct: 130 GLSLVQTTDFFYPLVEDPYMMGRIACANVLSDLYAMGITECDNMLMLLSVSQSMSEEERE 189
Query: 119 AKTALV 124
T L+
Sbjct: 190 KVTPLM 195
>gi|160948599 integrator complex subunit 1 [Homo sapiens]
Length = 2190
Score = 30.8 bits (68), Expect = 0.96
Identities = 26/95 (27%), Positives = 45/95 (47%), Gaps = 5/95 (5%)
Query: 116 ERDAKTALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLI 175
E D + ++K K R ++ L QD L+G K V L Y++ L SS +
Sbjct: 926 EEDDEGESKEQKAKKRQRQQKQRQLLGRLQDLLLGPKADEQTTCEV-LDYFLRRLGSSQV 984
Query: 176 SSFPLLKALKTRISNLPTVKKFLQPGSQRKPPMDE 210
+S + L + +L + L+ G +++PPM+E
Sbjct: 985 AS----RVLAMKGLSLVLSEGSLRDGEEKEPPMEE 1015
>gi|19913398 smoothelin isoform a [Homo sapiens]
Length = 940
Score = 30.0 bits (66), Expect = 1.6
Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 5/51 (9%)
Query: 35 LESAEDLDKLRN-DGSLLFQQVPMVEIDGMKLV----QTRAILNYIASKYN 80
L ED+ +LR D +L VP+VE+D M ++ + + Y+ S YN
Sbjct: 876 LLDTEDMVRLREPDWKMLVDCVPLVEVDDMMIMGKKPDPKCVFTYVQSLYN 926
>gi|44955921 ELK3 protein [Homo sapiens]
Length = 407
Score = 29.3 bits (64), Expect = 2.8
Identities = 17/55 (30%), Positives = 25/55 (45%), Gaps = 5/55 (9%)
Query: 168 EELDSSLISSFPLLKALKTRISNLPTVKKFLQPGSQRKPPMDEKSLEEARKIFRF 222
E + S L SSF + + N P K ++ +PP D +EE R + RF
Sbjct: 136 EYIHSGLYSSFTI-----NSLQNPPDAFKAIKTEKLEEPPEDSPPVEEVRTVIRF 185
>gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens]
Length = 998
Score = 29.3 bits (64), Expect = 2.8
Identities = 28/159 (17%), Positives = 67/159 (42%), Gaps = 29/159 (18%)
Query: 2 AEKPKLHYSNARGSMESIRWLLAAAG----VELEEKFLESAEDLDKLRNDGSLLFQQVPM 57
+E P L ++ GS ++ W ++ E K+ E +E + S + Q+
Sbjct: 454 SEVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEKSEGI------ASTVTSQMNS 507
Query: 58 VEIDGMK-------LVQTRAILNY----------IASKYNLYGKDMKERA--LIDMYTEG 98
V++DG++ V+ R + Y S+ + ++E+ ++ T G
Sbjct: 508 VQLDGLRPDARYVVQVRARTVAGYGQYSRPAEFETTSERGSGAQQLQEQLPLIVGSATAG 567
Query: 99 IVDLTEMILLLLICQPEERDAKTALVKEKIKNRYFPAFE 137
+V + ++++ ++C ++R + EK++ P +
Sbjct: 568 LVFVVAVVVIAIVCLRKQRHGSDSEYTEKLQQYIAPGMK 606
>gi|24797148 selenophosphate synthetase 1 [Homo sapiens]
Length = 392
Score = 29.3 bits (64), Expect = 2.8
Identities = 27/113 (23%), Positives = 47/113 (41%), Gaps = 15/113 (13%)
Query: 32 EKFLESAEDLDKLRNDGSLLFQQVPMVEID-----------GMKLVQTRAILNYIASKYN 80
+K LES ++ + + D L +P + I G+ LVQT + I
Sbjct: 39 QKLLESLQE-NHFQEDEQFLGAVMPRLGIGMDTCVIPLRHGGLSLVQTTDYIYPIVDDPY 97
Query: 81 LYGKDMKERALIDMYTEGIVDLTEMILLLLICQ---PEERDAKTALVKEKIKN 130
+ G+ L D+Y G+ + M++LL + ERD L+ + K+
Sbjct: 98 MMGRIACANVLSDLYAMGVTECDNMLMLLGVSNKMTDRERDKVMPLIIQGFKD 150
>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
Length = 2479
Score = 28.9 bits (63), Expect = 3.7
Identities = 29/119 (24%), Positives = 49/119 (41%)
Query: 101 DLTEMILLLLICQPEERDAKTALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHL 160
+L E + L + +++ A + + E A E+++ + Q N D H
Sbjct: 1725 NLVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAHLNVQQIVDRHT 1784
Query: 161 VELFYYVEELDSSLISSFPLLKALKTRISNLPTVKKFLQPGSQRKPPMDEKSLEEARKI 219
EL VE+L+ +L+ LK K R ++L L Q+K K L E +I
Sbjct: 1785 RELKTQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEI 1843
>gi|41281453 serine/threonine kinase 2 [Homo sapiens]
Length = 1235
Score = 28.9 bits (63), Expect = 3.7
Identities = 34/154 (22%), Positives = 64/154 (41%), Gaps = 15/154 (9%)
Query: 15 SMESIRWLLAAAGVELEEKFLESAEDLDKLRNDGSLLF-------QQVPMVEIDGMKLVQ 67
S + IR L+A A E+ E+ + E+ ++ + SL + + + KL Q
Sbjct: 296 SNKPIRELIAEAKAEVTEEVEDGKEEDEEEETENSLPIPASKRASSDLSIASSEEDKLSQ 355
Query: 68 TRAILNYIASKYN-------LYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDAK 120
IL ++ K L K + E+ D + + D+ E I + E +
Sbjct: 356 NACILESVSEKTERSNSEDKLNSKILNEKPTTDEPEKAVEDINEHITDAQLEAMTELHDR 415
Query: 121 TALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLS 154
TA++KE + + P E + + Q+ + N +S
Sbjct: 416 TAVIKENEREKR-PKLENLPDTEDQETVDINSVS 448
>gi|167466164 glutathione S-transferase theta 1 [Homo sapiens]
Length = 240
Score = 28.5 bits (62), Expect = 4.8
Identities = 15/47 (31%), Positives = 27/47 (57%), Gaps = 4/47 (8%)
Query: 53 QQVPMVEIDGMKLVQTRAILNYIASKYNL----YGKDMKERALIDMY 95
++VP ++ L ++ AIL Y+ KY + Y +D++ RA +D Y
Sbjct: 52 KKVPALKDGDFTLTESVAILLYLTRKYKVPDYWYPQDLQARARVDEY 98
>gi|33620755 YEATS domain containing 2 [Homo sapiens]
Length = 1422
Score = 28.5 bits (62), Expect = 4.8
Identities = 25/106 (23%), Positives = 50/106 (47%), Gaps = 20/106 (18%)
Query: 117 RDAKTALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLIS 176
RDA ++ IK ++ A E K H + + D L+E +++L + +++
Sbjct: 35 RDAAVQKIETIIKEQF--ALEMKNKEHEIEVI--------DQRLIEARRMMDKLRACIVA 84
Query: 177 SF----PLLKALK------TRISNLPTVKKFLQPGSQRKPPMDEKS 212
++ LLK + T + N P +KKFL+ S+ P ++++
Sbjct: 85 NYYASAGLLKVSEGSKTCDTMVFNHPAIKKFLESPSRSSSPANQRA 130
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,659,827
Number of Sequences: 37866
Number of extensions: 288815
Number of successful extensions: 962
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 923
Number of HSP's gapped (non-prelim): 32
length of query: 222
length of database: 18,247,518
effective HSP length: 98
effective length of query: 124
effective length of database: 14,536,650
effective search space: 1802544600
effective search space used: 1802544600
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.