Guide to the Human Genome
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Search of human proteins with 24308514

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|24308514 glutathione S-transferase alpha 5 [Homo sapiens]
         (222 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|24308514 glutathione S-transferase alpha 5 [Homo sapiens]          436   e-123
gi|22091454 glutathione S-transferase alpha 1 [Homo sapiens]          393   e-110
gi|215276987 glutathione S-transferase alpha 2 [Homo sapiens]         386   e-108
gi|24430144 glutathione S-transferase alpha 3 [Homo sapiens]          374   e-104
gi|113417526 PREDICTED: similar to glutathione S-transferase alp...   257   5e-69
gi|169169045 PREDICTED: similar to glutathione S-transferase alp...   256   1e-68
gi|113418092 PREDICTED: similar to glutathione S-transferase alp...   256   1e-68
gi|4504173 glutathione S-transferase alpha 4 [Homo sapiens]           248   3e-66
gi|4504183 glutathione transferase [Homo sapiens]                      82   3e-16
gi|7657457 prostaglandin-D synthase [Homo sapiens]                     70   1e-12
gi|4504175 glutathione S-transferase mu 2 isoform 1 [Homo sapiens]     66   2e-11
gi|23065552 glutathione S-transferase mu 3 [Homo sapiens]              65   5e-11
gi|215277000 glutathione S-transferase mu 2 isoform 2 [Homo sapi...    63   2e-10
gi|23065544 glutathione S-transferase mu 1 isoform 1 [Homo sapiens]    59   4e-09
gi|4504179 glutathione S-transferase mu 4 isoform 1 [Homo sapiens]     54   8e-08
gi|23065563 glutathione S-transferase mu 5 [Homo sapiens]              53   2e-07
gi|23065557 glutathione S-transferase mu 4 isoform 2 [Homo sapiens]    50   1e-06
gi|23065547 glutathione S-transferase mu 1 isoform 2 [Homo sapiens]    46   3e-05
gi|22202624 glutathione transferase zeta 1 isoform 1 [Homo sapiens]    46   3e-05
gi|22202622 glutathione transferase zeta 1 isoform 3 [Homo sapiens]    44   1e-04
gi|15011844 selenophosphate synthetase 2 [Homo sapiens]                32   0.56 
gi|160948599 integrator complex subunit 1 [Homo sapiens]               31   0.96 
gi|19913398 smoothelin isoform a [Homo sapiens]                        30   1.6  
gi|44955921 ELK3 protein [Homo sapiens]                                29   2.8  
gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens]             29   2.8  
gi|24797148 selenophosphate synthetase 1 [Homo sapiens]                29   2.8  
gi|109255234 centrosomal protein 290kDa [Homo sapiens]                 29   3.7  
gi|41281453 serine/threonine kinase 2 [Homo sapiens]                   29   3.7  
gi|167466164 glutathione S-transferase theta 1 [Homo sapiens]          28   4.8  
gi|33620755 YEATS domain containing 2 [Homo sapiens]                   28   4.8  

>gi|24308514 glutathione S-transferase alpha 5 [Homo sapiens]
          Length = 222

 Score =  436 bits (1121), Expect = e-123
 Identities = 222/222 (100%), Positives = 222/222 (100%)

Query: 1   MAEKPKLHYSNARGSMESIRWLLAAAGVELEEKFLESAEDLDKLRNDGSLLFQQVPMVEI 60
           MAEKPKLHYSNARGSMESIRWLLAAAGVELEEKFLESAEDLDKLRNDGSLLFQQVPMVEI
Sbjct: 1   MAEKPKLHYSNARGSMESIRWLLAAAGVELEEKFLESAEDLDKLRNDGSLLFQQVPMVEI 60

Query: 61  DGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDAK 120
           DGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDAK
Sbjct: 61  DGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDAK 120

Query: 121 TALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPL 180
           TALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPL
Sbjct: 121 TALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPL 180

Query: 181 LKALKTRISNLPTVKKFLQPGSQRKPPMDEKSLEEARKIFRF 222
           LKALKTRISNLPTVKKFLQPGSQRKPPMDEKSLEEARKIFRF
Sbjct: 181 LKALKTRISNLPTVKKFLQPGSQRKPPMDEKSLEEARKIFRF 222


>gi|22091454 glutathione S-transferase alpha 1 [Homo sapiens]
          Length = 222

 Score =  393 bits (1009), Expect = e-110
 Identities = 200/222 (90%), Positives = 207/222 (93%)

Query: 1   MAEKPKLHYSNARGSMESIRWLLAAAGVELEEKFLESAEDLDKLRNDGSLLFQQVPMVEI 60
           MAEKPKLHY NARG MES RWLLAAAGVE EEKF++SAEDLDKLRNDG L+FQQVPMVEI
Sbjct: 1   MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60

Query: 61  DGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDAK 120
           DGMKLVQTRAILNYIASKYNLYGKD+KERALIDMY EGI DL EMILLL +C PEE+DAK
Sbjct: 61  DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAK 120

Query: 121 TALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPL 180
            AL+KEKIKNRYFPAFEKVLKSH QDYLVGNKLS ADIHLVEL YYVEELDSSLISSFPL
Sbjct: 121 LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180

Query: 181 LKALKTRISNLPTVKKFLQPGSQRKPPMDEKSLEEARKIFRF 222
           LKALKTRISNLPTVKKFLQPGS RKPPMDEKSLEEARKIFRF
Sbjct: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFRF 222


>gi|215276987 glutathione S-transferase alpha 2 [Homo sapiens]
          Length = 222

 Score =  386 bits (992), Expect = e-108
 Identities = 197/222 (88%), Positives = 206/222 (92%)

Query: 1   MAEKPKLHYSNARGSMESIRWLLAAAGVELEEKFLESAEDLDKLRNDGSLLFQQVPMVEI 60
           MAEKPKLHYSN RG MESIRWLLAAAGVE EEKF++SAEDLDKLRNDG L+FQQVPMVEI
Sbjct: 1   MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60

Query: 61  DGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDAK 120
           DGMKLVQTRAILNYIASKYNLYGKD+KE+ALIDMY EGI DL EMILLL   QPEE+DAK
Sbjct: 61  DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK 120

Query: 121 TALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPL 180
            AL++EK KNRYFPAFEKVLKSH QDYLVGNKLS ADIHLVEL YYVEELDSSLISSFPL
Sbjct: 121 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180

Query: 181 LKALKTRISNLPTVKKFLQPGSQRKPPMDEKSLEEARKIFRF 222
           LKALKTRISNLPTVKKFLQPGS RKPPMDEKSLEE+RKIFRF
Sbjct: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF 222


>gi|24430144 glutathione S-transferase alpha 3 [Homo sapiens]
          Length = 222

 Score =  374 bits (959), Expect = e-104
 Identities = 190/222 (85%), Positives = 202/222 (90%)

Query: 1   MAEKPKLHYSNARGSMESIRWLLAAAGVELEEKFLESAEDLDKLRNDGSLLFQQVPMVEI 60
           MA KPKLHY N RG ME IRWLLAAAGVE EEKF+ SAEDL KLRNDGSL+FQQVPMVEI
Sbjct: 1   MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI 60

Query: 61  DGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDAK 120
           DGMKLVQTRAILNYIASKYNLYGKD+KERALIDMYTEG+ DL EMILLL +C+PEE+DAK
Sbjct: 61  DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120

Query: 121 TALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPL 180
            AL+KEK K+RYFPAFEKVL+SH QDYLVGNKLS ADI LVEL YYVEELDSSLIS+FPL
Sbjct: 121 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180

Query: 181 LKALKTRISNLPTVKKFLQPGSQRKPPMDEKSLEEARKIFRF 222
           LKALKTRISNLPTVKKFLQPGS RKPP D K+LEEARKIFRF
Sbjct: 181 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF 222


>gi|113417526 PREDICTED: similar to glutathione S-transferase alpha
           3 [Homo sapiens]
          Length = 216

 Score =  257 bits (657), Expect = 5e-69
 Identities = 140/210 (66%), Positives = 159/210 (75%), Gaps = 16/210 (7%)

Query: 28  VELEEKFLESAEDLDKLRNDGSLLFQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDMK 87
           VE E KFLESA+DL+KLRND S +FQQVPMVEIDGMKLVQTRAILNYIASKYNL GKD+K
Sbjct: 6   VESERKFLESAKDLEKLRNDESFMFQQVPMVEIDGMKLVQTRAILNYIASKYNLCGKDIK 65

Query: 88  ERA---------LIDMYTEGIVDLTEMILLLLICQPEERDAKTALVKEKIKNRYFPAFEK 138
           ERA          +DMY EG   L+E +L   +  PEE+DAK AL+KE   + YFP FE 
Sbjct: 66  ERAPYIWLFLSYRVDMYIEGRAGLSEKLLHCSLHPPEEKDAKLALIKEGTTSHYFPVFET 125

Query: 139 VLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPLLK-------ALKTRISNL 191
           VLKSH QDY +GNKLS ADIHLV+L Y+VEE DSSLIS+FP+LK       ALK RIS L
Sbjct: 126 VLKSHEQDYFIGNKLSQADIHLVKLLYHVEEPDSSLISNFPVLKAVLCALRALKIRISKL 185

Query: 192 PTVKKFLQPGSQRKPPMDEKSLEEARKIFR 221
           PTVKKFLQPGS RK P+D K L+EA KIF+
Sbjct: 186 PTVKKFLQPGSLRKLPIDAKGLQEATKIFK 215


>gi|169169045 PREDICTED: similar to glutathione S-transferase alpha
           3 [Homo sapiens]
          Length = 227

 Score =  256 bits (653), Expect = 1e-68
 Identities = 139/209 (66%), Positives = 158/209 (75%), Gaps = 16/209 (7%)

Query: 29  ELEEKFLESAEDLDKLRNDGSLLFQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDMKE 88
           E E KFLESA+DL+KLRND S +FQQVPMVEIDGMKLVQTRAILNYI SKYNL GKD+KE
Sbjct: 18  ESERKFLESAKDLEKLRNDESFMFQQVPMVEIDGMKLVQTRAILNYIVSKYNLCGKDIKE 77

Query: 89  RA---------LIDMYTEGIVDLTEMILLLLICQPEERDAKTALVKEKIKNRYFPAFEKV 139
           RA          +DMY EG   L+E +L   +  PEE+DAK AL+KE   + YFP FE V
Sbjct: 78  RAPYIWLFLSYRVDMYIEGRAGLSEKLLHCSLHPPEEKDAKLALIKEGTTSHYFPVFETV 137

Query: 140 LKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPLLK-------ALKTRISNLP 192
           LKSH QDYL+GNKLS ADIHLV+L Y+VEE DSSLIS+FP+LK       ALK RIS LP
Sbjct: 138 LKSHEQDYLIGNKLSQADIHLVKLLYHVEEPDSSLISNFPVLKAVLCALRALKIRISKLP 197

Query: 193 TVKKFLQPGSQRKPPMDEKSLEEARKIFR 221
           TVKKFLQPGS RK P+D K L+EA KIF+
Sbjct: 198 TVKKFLQPGSLRKLPIDAKGLQEATKIFK 226


>gi|113418092 PREDICTED: similar to glutathione S-transferase alpha
           3 [Homo sapiens]
          Length = 216

 Score =  256 bits (653), Expect = 1e-68
 Identities = 139/210 (66%), Positives = 158/210 (75%), Gaps = 16/210 (7%)

Query: 28  VELEEKFLESAEDLDKLRNDGSLLFQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDMK 87
           VE E KFLESA+DL+KLRND S +FQQVPMVEIDGMKLVQTRAILNYI SKYNL GKD+K
Sbjct: 6   VESERKFLESAKDLEKLRNDESFMFQQVPMVEIDGMKLVQTRAILNYIVSKYNLCGKDIK 65

Query: 88  ERA---------LIDMYTEGIVDLTEMILLLLICQPEERDAKTALVKEKIKNRYFPAFEK 138
           ERA          +DMY EG   L+E +L   +  PEE+DAK AL+KE   + YFP FE 
Sbjct: 66  ERAPYIWLFLSYRVDMYIEGRAGLSEKLLHCSLHPPEEKDAKLALIKEGTTSHYFPVFET 125

Query: 139 VLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPLLK-------ALKTRISNL 191
           VLKSH QDY +GNKLS ADIHLV+L Y+VEE DSSLIS+FP+LK       ALK RIS L
Sbjct: 126 VLKSHEQDYFIGNKLSQADIHLVKLLYHVEEPDSSLISNFPVLKAVLCALRALKIRISKL 185

Query: 192 PTVKKFLQPGSQRKPPMDEKSLEEARKIFR 221
           PTVKKFLQPGS RK P+D K L+EA KIF+
Sbjct: 186 PTVKKFLQPGSLRKLPIDAKGLQEATKIFK 215


>gi|4504173 glutathione S-transferase alpha 4 [Homo sapiens]
          Length = 222

 Score =  248 bits (633), Expect = 3e-66
 Identities = 118/221 (53%), Positives = 166/221 (75%)

Query: 1   MAEKPKLHYSNARGSMESIRWLLAAAGVELEEKFLESAEDLDKLRNDGSLLFQQVPMVEI 60
           MA +PKLHY N RG MES+RW+LAAAGVE +E+FLE+ E L KL++   LLFQQVPMVEI
Sbjct: 1   MAARPKLHYPNGRGRMESVRWVLAAAGVEFDEEFLETKEQLYKLQDGNHLLFQQVPMVEI 60

Query: 61  DGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDAK 120
           DGMKLVQTR+IL+YIA K+NL+GK++KER LIDMY EG +DL E++++    +P+++  +
Sbjct: 61  DGMKLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKE 120

Query: 121 TALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPL 180
              + +K   RYFP FEK+L+ H Q +LVGN+LS AD+ L++    +EE   +++S+FP 
Sbjct: 121 VVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPF 180

Query: 181 LKALKTRISNLPTVKKFLQPGSQRKPPMDEKSLEEARKIFR 221
           L+    ++SN+PT+K+FL+PGS++KPP DE  +     IFR
Sbjct: 181 LQEYTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFR 221


>gi|4504183 glutathione transferase [Homo sapiens]
          Length = 210

 Score = 82.4 bits (202), Expect = 3e-16
 Identities = 58/193 (30%), Positives = 99/193 (51%), Gaps = 9/193 (4%)

Query: 9   YSNARGSMESIRWLLAAAGVELEEKFLESAEDLDKLRNDGSLLFQQVPMVEIDGMKLVQT 68
           Y   RG   ++R LLA  G   +E+ + + E   +     S L+ Q+P  +   + L Q+
Sbjct: 8   YFPVRGRCAALRMLLADQGQSWKEEVV-TVETWQEGSLKASCLYGQLPKFQDGDLTLYQS 66

Query: 69  RAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEE-RDAKTALVKEK 127
             IL ++     LYGKD +E AL+DM  +G+ DL    + L+    E  +D     +  +
Sbjct: 67  NTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYTNYEAGKDDYVKALPGQ 126

Query: 128 IKNRYFPAFEKVLKSHR--QDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPLLKALK 185
           +K      FE +L  ++  + ++VG+++S+AD +L++L    E L    + +FPLL A  
Sbjct: 127 LK-----PFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDAFPLLSAYV 181

Query: 186 TRISNLPTVKKFL 198
            R+S  P +K FL
Sbjct: 182 GRLSARPKLKAFL 194


>gi|7657457 prostaglandin-D synthase [Homo sapiens]
          Length = 199

 Score = 70.5 bits (171), Expect = 1e-12
 Identities = 51/202 (25%), Positives = 100/202 (49%), Gaps = 10/202 (4%)

Query: 6   KLHYSNARGSMESIRWLLAAAGVELEEKFLESAEDLDKLRNDGSLLFQQVPMVEIDGMKL 65
           KL Y N RG  E IR++ A   ++ E+  +E A D  ++++  +L F ++P++E+DG+ L
Sbjct: 5   KLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQA-DWPEIKS--TLPFGKIPILEVDGLTL 61

Query: 66  VQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDAKTALVK 125
            Q+ AI  Y+    +L G    E+  +D     IVD  +  +       +++D K  +  
Sbjct: 62  HQSLAIARYLTKNTDLAGNTEMEQCHVD----AIVDTLDDFMSCFPWAEKKQDVKEQMFN 117

Query: 126 EKIKNRYFPAFEKVLKSH--RQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPLLKA 183
           E +     P   + L ++   +++L+GN ++WAD +       +      L+ + P L  
Sbjct: 118 ELLTYN-APHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPRLVT 176

Query: 184 LKTRISNLPTVKKFLQPGSQRK 205
           L+ ++  +P V  +++   Q K
Sbjct: 177 LRKKVQAIPAVANWIKRRPQTK 198


>gi|4504175 glutathione S-transferase mu 2 isoform 1 [Homo sapiens]
          Length = 218

 Score = 66.2 bits (160), Expect = 2e-11
 Identities = 61/206 (29%), Positives = 98/206 (47%), Gaps = 24/206 (11%)

Query: 7   LHYSNARGSMESIRWLLAAAGVELEEK--FLESAEDLDKLR--NDGSLL---FQQVPMVE 59
           L Y N RG   SIR LL       EEK   +  A D D+ +  N+   L   F  +P + 
Sbjct: 5   LGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 63

Query: 60  IDGM-KLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERD 118
           IDG  K+ Q+ AIL YIA K+NL G+  KE+   D+     +D + M L  L   P+   
Sbjct: 64  IDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMD-SRMQLAKLCYDPD--- 119

Query: 119 AKTALVKEKIKNRYFPAFEKVLKSH-----RQDYLVGNKLSWADIHLVELFYYVEELDSS 173
                  EK+K  Y  A  ++LK +     +Q + +G+K+++ D    ++    +  + S
Sbjct: 120 ------FEKLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPS 173

Query: 174 LISSFPLLKALKTRISNLPTVKKFLQ 199
            + +FP LK   +R   L  +  +++
Sbjct: 174 CLDAFPNLKDFISRFEGLEKISAYMK 199


>gi|23065552 glutathione S-transferase mu 3 [Homo sapiens]
          Length = 225

 Score = 65.1 bits (157), Expect = 5e-11
 Identities = 57/224 (25%), Positives = 90/224 (40%), Gaps = 22/224 (9%)

Query: 7   LHYSNARGSMESIRWLLAAAGVELEEKFLESAEDLDKLRNDG-------SLLFQQVPMVE 59
           L Y + RG   +IR LL       EEK     E  D  R+          L F  +P + 
Sbjct: 9   LGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLL 68

Query: 60  IDGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDA 119
               K+ Q+ AIL YIA K+N+ G+  +E+  +D+    ++D      L+ +C   +   
Sbjct: 69  DGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQ--LIRLCYSSDH-- 124

Query: 120 KTALVKEKIKNRYFPAFEKVLKSH-----RQDYLVGNKLSWADIHLVELFYYVEELDSSL 174
                 EK+K +Y       LK       +  +  G KL++ D    ++       D   
Sbjct: 125 ------EKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKC 178

Query: 175 ISSFPLLKALKTRISNLPTVKKFLQPGSQRKPPMDEKSLEEARK 218
           +  FP LKA   R   L  +  +LQ     K P++ K  +   K
Sbjct: 179 LDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 222


>gi|215277000 glutathione S-transferase mu 2 isoform 2 [Homo
           sapiens]
          Length = 191

 Score = 62.8 bits (151), Expect = 2e-10
 Identities = 60/197 (30%), Positives = 94/197 (47%), Gaps = 24/197 (12%)

Query: 7   LHYSNARGSMESIRWLLAAAGVELEEK--FLESAEDLDKLR--NDGSLL---FQQVPMVE 59
           L Y N RG   SIR LL       EEK   +  A D D+ +  N+   L   F  +P + 
Sbjct: 5   LGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 63

Query: 60  IDGM-KLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERD 118
           IDG  K+ Q+ AIL YIA K+NL G+  KE+   D+     +D + M L  L   P+   
Sbjct: 64  IDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMD-SRMQLAKLCYDPD--- 119

Query: 119 AKTALVKEKIKNRYFPAFEKVLKSH-----RQDYLVGNKLSWADIHLVELFYYVEELDSS 173
                  EK+K  Y  A  ++LK +     +Q + +G+K+++ D    ++    +  + S
Sbjct: 120 ------FEKLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPS 173

Query: 174 LISSFPLLKALKTRISN 190
            + +FP LK   +R  +
Sbjct: 174 CLDAFPNLKDFISRFEH 190


>gi|23065544 glutathione S-transferase mu 1 isoform 1 [Homo sapiens]
          Length = 218

 Score = 58.5 bits (140), Expect = 4e-09
 Identities = 53/205 (25%), Positives = 93/205 (45%), Gaps = 22/205 (10%)

Query: 7   LHYSNARGSMESIRWLLAAAGVELEEK--FLESAEDLDKLR--NDGSLL---FQQVPMVE 59
           L Y + RG   +IR LL       EEK   +  A D D+ +  N+   L   F  +P + 
Sbjct: 5   LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64

Query: 60  IDGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDA 119
               K+ Q+ AIL YIA K+NL G+  +E+  +D+     +D   M L ++   PE    
Sbjct: 65  DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMD-NHMQLGMICYNPE---- 119

Query: 120 KTALVKEKIKNRYFPAFEKVLKSH-----RQDYLVGNKLSWADIHLVELFYYVEELDSSL 174
                 EK+K +Y     + LK +     ++ +  GNK+++ D  + ++       +   
Sbjct: 120 -----FEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKC 174

Query: 175 ISSFPLLKALKTRISNLPTVKKFLQ 199
           + +FP LK   +R   L  +  +++
Sbjct: 175 LDAFPNLKDFISRFEGLEKISAYMK 199


>gi|4504179 glutathione S-transferase mu 4 isoform 1 [Homo sapiens]
          Length = 218

 Score = 54.3 bits (129), Expect = 8e-08
 Identities = 50/205 (24%), Positives = 91/205 (44%), Gaps = 22/205 (10%)

Query: 7   LHYSNARGSMESIRWLLAAAGVELEEK--FLESAEDLDKLR--NDGSLL---FQQVPMVE 59
           L Y + RG   +IR LL       EEK   +  A D D+ +  N+   L   F  +P + 
Sbjct: 5   LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64

Query: 60  IDGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDA 119
               K+ Q+ AIL YIA K+NL G+  +E+  +D+     +D++    L  +C   +   
Sbjct: 65  DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQ--LARVCYSPD--- 119

Query: 120 KTALVKEKIKNRYFPAFEKVLKSHRQ-----DYLVGNKLSWADIHLVELFYYVEELDSSL 174
                 EK+K  Y      +++   Q      + VG+K+++ D    ++       + + 
Sbjct: 120 -----FEKLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNC 174

Query: 175 ISSFPLLKALKTRISNLPTVKKFLQ 199
           + +FP LK   +R   L  +  +++
Sbjct: 175 LDAFPNLKDFISRFEGLEKISAYMK 199


>gi|23065563 glutathione S-transferase mu 5 [Homo sapiens]
          Length = 218

 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 51/205 (24%), Positives = 91/205 (44%), Gaps = 22/205 (10%)

Query: 7   LHYSNARGSMESIRWLLAAAGVELEEK--FLESAEDLDKLR--NDGSLL---FQQVPMVE 59
           L Y + RG   +IR LL        EK   L  A D D+ +  N+   L   F  +P + 
Sbjct: 5   LGYWDIRGLAHAIRLLLEYTDSSYVEKKYTLGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64

Query: 60  IDGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDA 119
               K+ Q+ AIL YIA K+NL G+  +E+  +D+    ++D   M L+ L   P+    
Sbjct: 65  DGAHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQVMD-NHMELVRLCYDPD---- 119

Query: 120 KTALVKEKIKNRYFPAFEKVLKSH-----RQDYLVGNKLSWADIHLVELFYYVEELDSSL 174
                 EK+K +Y     + LK +     ++ +  G+K+++ D    ++       +   
Sbjct: 120 -----FEKLKPKYLEELPEKLKLYSEFLGKRPWFAGDKITFVDFLAYDVLDMKRIFEPKC 174

Query: 175 ISSFPLLKALKTRISNLPTVKKFLQ 199
           + +F  LK   +R   L  +  +++
Sbjct: 175 LDAFLNLKDFISRFEGLKKISAYMK 199


>gi|23065557 glutathione S-transferase mu 4 isoform 2 [Homo sapiens]
          Length = 195

 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 49/193 (25%), Positives = 86/193 (44%), Gaps = 22/193 (11%)

Query: 7   LHYSNARGSMESIRWLLAAAGVELEEK--FLESAEDLDKLR--NDGSLL---FQQVPMVE 59
           L Y + RG   +IR LL       EEK   +  A D D+ +  N+   L   F  +P + 
Sbjct: 5   LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64

Query: 60  IDGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDA 119
               K+ Q+ AIL YIA K+NL G+  +E+  +D+     +D++    L  +C   +   
Sbjct: 65  DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQ--LARVCYSPD--- 119

Query: 120 KTALVKEKIKNRYFPAFEKVLKSHRQ-----DYLVGNKLSWADIHLVELFYYVEELDSSL 174
                 EK+K  Y      +++   Q      + VG+K+++ D    ++       + + 
Sbjct: 120 -----FEKLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNC 174

Query: 175 ISSFPLLKALKTR 187
           + +FP LK   +R
Sbjct: 175 LDAFPNLKDFISR 187


>gi|23065547 glutathione S-transferase mu 1 isoform 2 [Homo sapiens]
          Length = 181

 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 46/158 (29%), Positives = 72/158 (45%), Gaps = 22/158 (13%)

Query: 7   LHYSNARGSMESIRWLLAAAGVELEEK--FLESAEDLDKLR--NDGSLL---FQQVPMVE 59
           L Y + RG   +IR LL       EEK   +  A D D+ +  N+   L   F  +P + 
Sbjct: 5   LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64

Query: 60  IDGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDA 119
               K+ Q+ AIL YIA K+NL G+  +E+  +D+     +D   M L ++   PE    
Sbjct: 65  DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMD-NHMQLGMICYNPE---- 119

Query: 120 KTALVKEKIKNRYFPAFEKVLKSH-----RQDYLVGNK 152
                 EK+K +Y     + LK +     ++ +  GNK
Sbjct: 120 -----FEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNK 152


>gi|22202624 glutathione transferase zeta 1 isoform 1 [Homo sapiens]
          Length = 216

 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 51/194 (26%), Positives = 91/194 (46%), Gaps = 10/194 (5%)

Query: 2   AEKPKLHYSNARGSME-SIRWLLAAAGVELEEKFLESAEDL-DKLRNDGSLL--FQQVPM 57
           A KP L YS  R S    +R  LA  G++ E   +   +D   +   D   L   +QVP 
Sbjct: 3   AGKPIL-YSYFRSSCSWRVRIALALKGIDYETVPINLIKDGGQQFSKDFQALNPMKQVPT 61

Query: 58  VEIDGMKLVQTRAILNYIASKY---NLYGKDMKERALIDMYTEGIVDLTEMILLLLICQP 114
           ++IDG+ + Q+ AI+ Y+        L  +D K+RA + M ++ I    + +  L + + 
Sbjct: 62  LKIDGITIHQSLAIIEYLEEMRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQNLSVLKQ 121

Query: 115 EERDAKTALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSL 174
              + +    +  I    F A E++L+S    Y VG++++ AD+ LV      E     L
Sbjct: 122 VGEEMQLTWAQNAI-TCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAERFKVDL 180

Query: 175 ISSFPLLKALKTRI 188
            + +P + ++  R+
Sbjct: 181 -TPYPTISSINKRL 193


>gi|22202622 glutathione transferase zeta 1 isoform 3 [Homo sapiens]
          Length = 161

 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 35/139 (25%), Positives = 69/139 (49%), Gaps = 5/139 (3%)

Query: 53  QQVPMVEIDGMKLVQTRAILNYIASKY---NLYGKDMKERALIDMYTEGIVDLTEMILLL 109
           +QVP ++IDG+ + Q+ AI+ Y+        L  +D K+RA + M ++ I    + +  L
Sbjct: 2   KQVPTLKIDGITIHQSLAIIEYLEEMRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQNL 61

Query: 110 LICQPEERDAKTALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHLVELFYYVEE 169
            + +    + +    +  I    F A E++L+S    Y VG++++ AD+ LV      E 
Sbjct: 62  SVLKQVGEEMQLTWAQNAI-TCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAER 120

Query: 170 LDSSLISSFPLLKALKTRI 188
               L + +P + ++  R+
Sbjct: 121 FKVDL-TPYPTISSINKRL 138


>gi|15011844 selenophosphate synthetase 2 [Homo sapiens]
          Length = 448

 Score = 31.6 bits (70), Expect = 0.56
 Identities = 20/66 (30%), Positives = 31/66 (46%), Gaps = 3/66 (4%)

Query: 62  GMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQ---PEERD 118
           G+ LVQT      +     + G+      L D+Y  GI +   M++LL + Q    EER+
Sbjct: 130 GLSLVQTTDFFYPLVEDPYMMGRIACANVLSDLYAMGITECDNMLMLLSVSQSMSEEERE 189

Query: 119 AKTALV 124
             T L+
Sbjct: 190 KVTPLM 195


>gi|160948599 integrator complex subunit 1 [Homo sapiens]
          Length = 2190

 Score = 30.8 bits (68), Expect = 0.96
 Identities = 26/95 (27%), Positives = 45/95 (47%), Gaps = 5/95 (5%)

Query: 116  ERDAKTALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLI 175
            E D +    ++K K R     ++ L    QD L+G K        V L Y++  L SS +
Sbjct: 926  EEDDEGESKEQKAKKRQRQQKQRQLLGRLQDLLLGPKADEQTTCEV-LDYFLRRLGSSQV 984

Query: 176  SSFPLLKALKTRISNLPTVKKFLQPGSQRKPPMDE 210
            +S    + L  +  +L   +  L+ G +++PPM+E
Sbjct: 985  AS----RVLAMKGLSLVLSEGSLRDGEEKEPPMEE 1015


>gi|19913398 smoothelin isoform a [Homo sapiens]
          Length = 940

 Score = 30.0 bits (66), Expect = 1.6
 Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 5/51 (9%)

Query: 35  LESAEDLDKLRN-DGSLLFQQVPMVEIDGMKLV----QTRAILNYIASKYN 80
           L   ED+ +LR  D  +L   VP+VE+D M ++      + +  Y+ S YN
Sbjct: 876 LLDTEDMVRLREPDWKMLVDCVPLVEVDDMMIMGKKPDPKCVFTYVQSLYN 926


>gi|44955921 ELK3 protein [Homo sapiens]
          Length = 407

 Score = 29.3 bits (64), Expect = 2.8
 Identities = 17/55 (30%), Positives = 25/55 (45%), Gaps = 5/55 (9%)

Query: 168 EELDSSLISSFPLLKALKTRISNLPTVKKFLQPGSQRKPPMDEKSLEEARKIFRF 222
           E + S L SSF +       + N P   K ++     +PP D   +EE R + RF
Sbjct: 136 EYIHSGLYSSFTI-----NSLQNPPDAFKAIKTEKLEEPPEDSPPVEEVRTVIRF 185


>gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens]
          Length = 998

 Score = 29.3 bits (64), Expect = 2.8
 Identities = 28/159 (17%), Positives = 67/159 (42%), Gaps = 29/159 (18%)

Query: 2   AEKPKLHYSNARGSMESIRWLLAAAG----VELEEKFLESAEDLDKLRNDGSLLFQQVPM 57
           +E P L   ++ GS  ++ W          ++ E K+ E +E +       S +  Q+  
Sbjct: 454 SEVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEKSEGI------ASTVTSQMNS 507

Query: 58  VEIDGMK-------LVQTRAILNY----------IASKYNLYGKDMKERA--LIDMYTEG 98
           V++DG++        V+ R +  Y            S+     + ++E+   ++   T G
Sbjct: 508 VQLDGLRPDARYVVQVRARTVAGYGQYSRPAEFETTSERGSGAQQLQEQLPLIVGSATAG 567

Query: 99  IVDLTEMILLLLICQPEERDAKTALVKEKIKNRYFPAFE 137
           +V +  ++++ ++C  ++R    +   EK++    P  +
Sbjct: 568 LVFVVAVVVIAIVCLRKQRHGSDSEYTEKLQQYIAPGMK 606


>gi|24797148 selenophosphate synthetase 1 [Homo sapiens]
          Length = 392

 Score = 29.3 bits (64), Expect = 2.8
 Identities = 27/113 (23%), Positives = 47/113 (41%), Gaps = 15/113 (13%)

Query: 32  EKFLESAEDLDKLRNDGSLLFQQVPMVEID-----------GMKLVQTRAILNYIASKYN 80
           +K LES ++ +  + D   L   +P + I            G+ LVQT   +  I     
Sbjct: 39  QKLLESLQE-NHFQEDEQFLGAVMPRLGIGMDTCVIPLRHGGLSLVQTTDYIYPIVDDPY 97

Query: 81  LYGKDMKERALIDMYTEGIVDLTEMILLLLICQ---PEERDAKTALVKEKIKN 130
           + G+      L D+Y  G+ +   M++LL +       ERD    L+ +  K+
Sbjct: 98  MMGRIACANVLSDLYAMGVTECDNMLMLLGVSNKMTDRERDKVMPLIIQGFKD 150


>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
          Length = 2479

 Score = 28.9 bits (63), Expect = 3.7
 Identities = 29/119 (24%), Positives = 49/119 (41%)

Query: 101  DLTEMILLLLICQPEERDAKTALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHL 160
            +L E +   L  + +++ A +  + E        A E+++ +  Q     N     D H 
Sbjct: 1725 NLVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAHLNVQQIVDRHT 1784

Query: 161  VELFYYVEELDSSLISSFPLLKALKTRISNLPTVKKFLQPGSQRKPPMDEKSLEEARKI 219
             EL   VE+L+ +L+     LK  K R ++L      L    Q+K     K L E  +I
Sbjct: 1785 RELKTQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEI 1843


>gi|41281453 serine/threonine kinase 2 [Homo sapiens]
          Length = 1235

 Score = 28.9 bits (63), Expect = 3.7
 Identities = 34/154 (22%), Positives = 64/154 (41%), Gaps = 15/154 (9%)

Query: 15  SMESIRWLLAAAGVELEEKFLESAEDLDKLRNDGSLLF-------QQVPMVEIDGMKLVQ 67
           S + IR L+A A  E+ E+  +  E+ ++   + SL           + +   +  KL Q
Sbjct: 296 SNKPIRELIAEAKAEVTEEVEDGKEEDEEEETENSLPIPASKRASSDLSIASSEEDKLSQ 355

Query: 68  TRAILNYIASKYN-------LYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDAK 120
              IL  ++ K         L  K + E+   D   + + D+ E I    +    E   +
Sbjct: 356 NACILESVSEKTERSNSEDKLNSKILNEKPTTDEPEKAVEDINEHITDAQLEAMTELHDR 415

Query: 121 TALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLS 154
           TA++KE  + +  P  E +  +  Q+ +  N +S
Sbjct: 416 TAVIKENEREKR-PKLENLPDTEDQETVDINSVS 448


>gi|167466164 glutathione S-transferase theta 1 [Homo sapiens]
          Length = 240

 Score = 28.5 bits (62), Expect = 4.8
 Identities = 15/47 (31%), Positives = 27/47 (57%), Gaps = 4/47 (8%)

Query: 53 QQVPMVEIDGMKLVQTRAILNYIASKYNL----YGKDMKERALIDMY 95
          ++VP ++     L ++ AIL Y+  KY +    Y +D++ RA +D Y
Sbjct: 52 KKVPALKDGDFTLTESVAILLYLTRKYKVPDYWYPQDLQARARVDEY 98


>gi|33620755 YEATS domain containing 2 [Homo sapiens]
          Length = 1422

 Score = 28.5 bits (62), Expect = 4.8
 Identities = 25/106 (23%), Positives = 50/106 (47%), Gaps = 20/106 (18%)

Query: 117 RDAKTALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLIS 176
           RDA    ++  IK ++  A E   K H  + +        D  L+E    +++L + +++
Sbjct: 35  RDAAVQKIETIIKEQF--ALEMKNKEHEIEVI--------DQRLIEARRMMDKLRACIVA 84

Query: 177 SF----PLLKALK------TRISNLPTVKKFLQPGSQRKPPMDEKS 212
           ++     LLK  +      T + N P +KKFL+  S+   P ++++
Sbjct: 85  NYYASAGLLKVSEGSKTCDTMVFNHPAIKKFLESPSRSSSPANQRA 130


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,659,827
Number of Sequences: 37866
Number of extensions: 288815
Number of successful extensions: 962
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 923
Number of HSP's gapped (non-prelim): 32
length of query: 222
length of database: 18,247,518
effective HSP length: 98
effective length of query: 124
effective length of database: 14,536,650
effective search space: 1802544600
effective search space used: 1802544600
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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