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Search of human proteins with 24308127
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24308127 DnaJ (Hsp40) homolog, subfamily C, member 10 [Homo
sapiens]
(793 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24308127 DnaJ (Hsp40) homolog, subfamily C, member 10 [Homo s... 1664 0.0
gi|5031973 protein disulfide isomerase A6 [Homo sapiens] 133 7e-31
gi|42794771 thioredoxin domain containing 5 isoform 1 precursor ... 120 4e-27
gi|5803121 protein disulfide isomerase A5 [Homo sapiens] 111 3e-24
gi|224493972 thioredoxin domain containing 5 isoform 3 [Homo sap... 107 6e-23
gi|56687498 DnaJ (Hsp40) homolog, subfamily C, member 16 [Homo s... 107 6e-23
gi|7706495 DnaJ (Hsp40) homolog, subfamily B, member 11 precurso... 102 2e-21
gi|4758304 protein disulfide isomerase A4 [Homo sapiens] 94 5e-19
gi|6631085 DnaJ (Hsp40) homolog, subfamily B, member 4 [Homo sap... 82 3e-15
gi|17388799 DnaJ (Hsp40) homolog, subfamily B, member 6 isoform ... 80 1e-14
gi|4885495 DnaJ (Hsp40) homolog, subfamily B, member 6 isoform b... 80 1e-14
gi|205360840 DnaJ (Hsp40) homolog, subfamily A, member 3 isoform... 79 1e-14
gi|205360838 DnaJ (Hsp40) homolog, subfamily A, member 3 isoform... 79 1e-14
gi|9558755 DnaJ (Hsp40) homolog, subfamily B, member 9 [Homo sap... 79 2e-14
gi|201862587 DnaJ (Hsp40) homolog, subfamily B, member 5 isoform... 78 3e-14
gi|201862518 DnaJ (Hsp40) homolog, subfamily B, member 5 isoform... 78 3e-14
gi|56549115 DnaJ (Hsp40) homolog, subfamily B, member 5 isoform ... 78 3e-14
gi|45504382 DnaJ (Hsp40) homolog, subfamily C, member 5 [Homo sa... 78 4e-14
gi|5031741 DnaJ subfamily A member 2 [Homo sapiens] 76 1e-13
gi|21553335 DnaJ (Hsp40) homolog, subfamily B, member 7 [Homo sa... 76 1e-13
gi|29126218 DnaJ (Hsp40) homolog, subfamily C, member 5 beta [Ho... 75 2e-13
gi|47777312 DnaJ (Hsp40) homolog, subfamily B, member 3 [Homo sa... 75 2e-13
gi|21361657 protein disulfide-isomerase A3 precursor [Homo sapiens] 74 5e-13
gi|4504511 DnaJ (Hsp40) homolog, subfamily A, member 1 [Homo sap... 72 3e-12
gi|5453690 DnaJ (Hsp40) homolog, subfamily B, member 1 [Homo sap... 70 1e-11
gi|22749377 DnaJ (Hsp40) homolog, subfamily C, member 18 [Homo s... 70 1e-11
gi|21361912 DnaJ (Hsp40) homolog, subfamily C, member 1 [Homo sa... 69 2e-11
gi|194328760 DnaJ (Hsp40) homolog, subfamily A, member 4 isoform... 69 2e-11
gi|194328758 DnaJ (Hsp40) homolog, subfamily A, member 4 isoform... 69 2e-11
gi|39204547 testis spermatogenesis apoptosis-related protein 6 [... 68 3e-11
>gi|24308127 DnaJ (Hsp40) homolog, subfamily C, member 10 [Homo
sapiens]
Length = 793
Score = 1664 bits (4308), Expect = 0.0
Identities = 793/793 (100%), Positives = 793/793 (100%)
Query: 1 MGVWLNKDDYIRDLKRIILCFLIVYMAILVGTDQDFYSLLGVSKTASSREIRQAFKKLAL 60
MGVWLNKDDYIRDLKRIILCFLIVYMAILVGTDQDFYSLLGVSKTASSREIRQAFKKLAL
Sbjct: 1 MGVWLNKDDYIRDLKRIILCFLIVYMAILVGTDQDFYSLLGVSKTASSREIRQAFKKLAL 60
Query: 61 KLHPDKNPNNPNAHGDFLKINRAYEVLKDEDLRKKYDKYGEKGLEDNQGGQYESWNYYRY 120
KLHPDKNPNNPNAHGDFLKINRAYEVLKDEDLRKKYDKYGEKGLEDNQGGQYESWNYYRY
Sbjct: 61 KLHPDKNPNNPNAHGDFLKINRAYEVLKDEDLRKKYDKYGEKGLEDNQGGQYESWNYYRY 120
Query: 121 DFGIYDDDPEIITLERREFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFAKEVDGLLR 180
DFGIYDDDPEIITLERREFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFAKEVDGLLR
Sbjct: 121 DFGIYDDDPEIITLERREFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFAKEVDGLLR 180
Query: 181 IGAVNCGDDRMLCRMKGVNSYPSLFIFRSGMAPVKYHGDRSKESLVSFAMQHVRSTVTEL 240
IGAVNCGDDRMLCRMKGVNSYPSLFIFRSGMAPVKYHGDRSKESLVSFAMQHVRSTVTEL
Sbjct: 181 IGAVNCGDDRMLCRMKGVNSYPSLFIFRSGMAPVKYHGDRSKESLVSFAMQHVRSTVTEL 240
Query: 241 WTGNFVNSIQTAFAAGIGWLITFCSKGGDCLTSQTRLRLSGMLDGLVNVGWMDCATQDNL 300
WTGNFVNSIQTAFAAGIGWLITFCSKGGDCLTSQTRLRLSGMLDGLVNVGWMDCATQDNL
Sbjct: 241 WTGNFVNSIQTAFAAGIGWLITFCSKGGDCLTSQTRLRLSGMLDGLVNVGWMDCATQDNL 300
Query: 301 CKSLDITTSTTAYFPPGATLNNKEKNSILFLNSLDAKEIYLEVIHNLPDFELLSANTLED 360
CKSLDITTSTTAYFPPGATLNNKEKNSILFLNSLDAKEIYLEVIHNLPDFELLSANTLED
Sbjct: 301 CKSLDITTSTTAYFPPGATLNNKEKNSILFLNSLDAKEIYLEVIHNLPDFELLSANTLED 360
Query: 361 RLAHHRWLLFFHFGKNENSNDPELKKLKTLLKNDHIQVGRFDCSSAPDICSNLYVFQPSL 420
RLAHHRWLLFFHFGKNENSNDPELKKLKTLLKNDHIQVGRFDCSSAPDICSNLYVFQPSL
Sbjct: 361 RLAHHRWLLFFHFGKNENSNDPELKKLKTLLKNDHIQVGRFDCSSAPDICSNLYVFQPSL 420
Query: 421 AVFKGQGTKEYEIHHGKKILYDILAFAKESVNSHVTTLGPQNFPANDKEPWLVDFFAPWC 480
AVFKGQGTKEYEIHHGKKILYDILAFAKESVNSHVTTLGPQNFPANDKEPWLVDFFAPWC
Sbjct: 421 AVFKGQGTKEYEIHHGKKILYDILAFAKESVNSHVTTLGPQNFPANDKEPWLVDFFAPWC 480
Query: 481 PPCRALLPELRRASNLLYGQLKFGTLDCTVHEGLCNMYNIQAYPTTVVFNQSNIHEYEGH 540
PPCRALLPELRRASNLLYGQLKFGTLDCTVHEGLCNMYNIQAYPTTVVFNQSNIHEYEGH
Sbjct: 481 PPCRALLPELRRASNLLYGQLKFGTLDCTVHEGLCNMYNIQAYPTTVVFNQSNIHEYEGH 540
Query: 541 HSAEQILEFIEDLMNPSVVSLTPTTFNELVTQRKHNEVWMVDFYSPWCHPCQVLMPEWKR 600
HSAEQILEFIEDLMNPSVVSLTPTTFNELVTQRKHNEVWMVDFYSPWCHPCQVLMPEWKR
Sbjct: 541 HSAEQILEFIEDLMNPSVVSLTPTTFNELVTQRKHNEVWMVDFYSPWCHPCQVLMPEWKR 600
Query: 601 MARTLTGLINVGSIDCQQYHSFCAQENVQRYPEIRFFPPKSNKAYHYHSYNGWNRDAYSL 660
MARTLTGLINVGSIDCQQYHSFCAQENVQRYPEIRFFPPKSNKAYHYHSYNGWNRDAYSL
Sbjct: 601 MARTLTGLINVGSIDCQQYHSFCAQENVQRYPEIRFFPPKSNKAYHYHSYNGWNRDAYSL 660
Query: 661 RIWGLGFLPQVSTDLTPQTFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKGK 720
RIWGLGFLPQVSTDLTPQTFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKGK
Sbjct: 661 RIWGLGFLPQVSTDLTPQTFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKGK 720
Query: 721 VKAGKVDCQAYAQTCQKAGIRAYPTVKFYFYERAKRNFQEEQINTRDAKAIAALISEKLE 780
VKAGKVDCQAYAQTCQKAGIRAYPTVKFYFYERAKRNFQEEQINTRDAKAIAALISEKLE
Sbjct: 721 VKAGKVDCQAYAQTCQKAGIRAYPTVKFYFYERAKRNFQEEQINTRDAKAIAALISEKLE 780
Query: 781 TLRNQGKRNKDEL 793
TLRNQGKRNKDEL
Sbjct: 781 TLRNQGKRNKDEL 793
>gi|5031973 protein disulfide isomerase A6 [Homo sapiens]
Length = 440
Score = 133 bits (334), Expect = 7e-31
Identities = 73/219 (33%), Positives = 107/219 (48%), Gaps = 29/219 (13%)
Query: 558 VVSLTPTTFNELVTQRKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTLTGLINVGSIDCQ 617
V+ LTP+ FN V Q + +W+V+FY+PWC CQ L PEWK+ A L ++ VG++D
Sbjct: 27 VIELTPSNFNREVIQS--DSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVDAD 84
Query: 618 QYHSFCAQENVQRYPEIRFFPPKSNKAYHYH--------------SYNGWNRDAYSLRIW 663
++HS Q VQ +P I+ F N+ Y + +D R
Sbjct: 85 KHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSG 144
Query: 664 GLGFLPQVSTD---------LTPQTFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLA 714
G Q +D LT +F + VL ++ W+++FYAPWCG C+N PE+ A
Sbjct: 145 GYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAA 204
Query: 715 RMI----KGKVKAGKVDCQAYAQTCQKAGIRAYPTVKFY 749
+ KGKVK VD + GIR +PT+K +
Sbjct: 205 SEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIF 243
Score = 102 bits (254), Expect = 1e-21
Identities = 61/224 (27%), Positives = 103/224 (45%), Gaps = 38/224 (16%)
Query: 450 SVNSHVTTLGPQNFPAN---DKEPWLVDFFAPWCPPCRALLPELRRASNLLYGQLKFGTL 506
S + V L P NF WLV+F+APWC C+ L PE ++A+ L +K G +
Sbjct: 22 SSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAV 81
Query: 507 DCTVHEGLCNMYNIQAYPTTVVF--NQSNIHEYEGHHSAEQILE--------FIEDLMN- 555
D H L Y +Q +PT +F N++ +Y+G + E I++ ++D +
Sbjct: 82 DADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGG 141
Query: 556 ------------------PSVVSLTPTTFNELVTQRKHNEVWMVDFYSPWCHPCQVLMPE 597
V+ LT +F++ V + +VWMV+FY+PWC C+ L PE
Sbjct: 142 RSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSE--DVWMVEFYAPWCGHCKNLEPE 199
Query: 598 WKRMARTL----TGLINVGSIDCQQYHSFCAQENVQRYPEIRFF 637
W A + G + + ++D ++ ++ +P I+ F
Sbjct: 200 WAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIF 243
Score = 75.9 bits (185), Expect = 1e-13
Identities = 34/98 (34%), Positives = 56/98 (57%), Gaps = 3/98 (3%)
Query: 674 DLTPQTFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKGKVKAGKVDCQAYAQ 733
+LTP F+ +V+Q + W+++FYAPWCG CQ PE++ A +K VK G VD +
Sbjct: 29 ELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVDADKHHS 88
Query: 734 TCQKAGIRAYPTVKFYFYERAKRNFQEEQINTRDAKAI 771
+ G++ +PT+K + + +N E+ R +AI
Sbjct: 89 LGGQYGVQGFPTIKIF---GSNKNRPEDYQGGRTGEAI 123
Score = 74.7 bits (182), Expect = 3e-13
Identities = 39/119 (32%), Positives = 60/119 (50%), Gaps = 2/119 (1%)
Query: 123 GIYDDDPEIITLERREFDAAV-NSGELWFVNFYSPGCSHCHDLAPTWRDFAKEVDGLLRI 181
G+Y ++I L F+ V S LW V FY+P C HC L P W+ A + ++++
Sbjct: 19 GLYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKV 78
Query: 182 GAVNCGDDRMLCRMKGVNSYPSLFIFRSGM-APVKYHGDRSKESLVSFAMQHVRSTVTE 239
GAV+ L GV +P++ IF S P Y G R+ E++V A+ +R V +
Sbjct: 79 GAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKD 137
Score = 74.7 bits (182), Expect = 3e-13
Identities = 40/132 (30%), Positives = 70/132 (53%), Gaps = 5/132 (3%)
Query: 104 LEDNQGGQYESWNYYRYDFGIYDDDPEIITLERREFDAAV-NSGELWFVNFYSPGCSHCH 162
++D GG+ ++ + ++I L FD V +S ++W V FY+P C HC
Sbjct: 135 VKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCK 194
Query: 163 DLAPTWRDFAKEV----DGLLRIGAVNCGDDRMLCRMKGVNSYPSLFIFRSGMAPVKYHG 218
+L P W A EV G +++ AV+ +++L G+ +P++ IF+ G +PV Y G
Sbjct: 195 NLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQKGESPVDYDG 254
Query: 219 DRSKESLVSFAM 230
R++ +VS A+
Sbjct: 255 GRTRSDIVSRAL 266
Score = 57.4 bits (137), Expect = 5e-08
Identities = 28/95 (29%), Positives = 53/95 (55%), Gaps = 5/95 (5%)
Query: 466 NDKEPWLVDFFAPWCPPCRALLPELRRASNLLY----GQLKFGTLDCTVHEGLCNMYNIQ 521
+ ++ W+V+F+APWC C+ L PE A++ + G++K +D TV++ L + Y I+
Sbjct: 176 DSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIR 235
Query: 522 AYPTTVVFNQSNIH-EYEGHHSAEQILEFIEDLMN 555
+PT +F + +Y+G + I+ DL +
Sbjct: 236 GFPTIKIFQKGESPVDYDGGRTRSDIVSRALDLFS 270
>gi|42794771 thioredoxin domain containing 5 isoform 1 precursor
[Homo sapiens]
Length = 432
Score = 120 bits (302), Expect = 4e-27
Identities = 86/333 (25%), Positives = 140/333 (42%), Gaps = 68/333 (20%)
Query: 473 VDFFAPWCPPCRALLPELR----RASNLLYGQLKFGTLDCTVHEGLCNMYNIQAYPTTVV 528
V FFAPWC C+ L P + +++ ++ +DCT H +C+ ++ YPT +
Sbjct: 82 VMFFAPWCGHCQRLQPTWNDLGDKYNSMEDAKVYVAKVDCTAHSDVCSAQGVRGYPTLKL 141
Query: 529 FNQ-SNIHEYEGHHSAEQILEFIEDLMNPSVVS-------------------LTPTTFNE 568
F +Y+G + + ++ +N V+ L+ + F
Sbjct: 142 FKPGQEAVKYQGPRDFQTLENWMLQTLNEEPVTPEPEVEPPSAPELKQGLYELSASNFEL 201
Query: 569 LVTQRKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTL--TGLINVGSIDCQQYHSFCAQE 626
V Q H + F++PWC C+ L P W+++A L + + +G +DC Q++ C+
Sbjct: 202 HVAQGDH----FIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYELCSGN 257
Query: 627 NVQRYPEIRFFPPKSNKAYHYHSYNGWNRDAYSLRIWGLGFLPQVSTD------------ 674
V+ YP + +F Y G RD SLR + L + T
Sbjct: 258 QVRGYPTLLWF----RDGKKVDQYKG-KRDLESLREYVESQLQRTETGATETVTPSEAPV 312
Query: 675 --------------LTPQTFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARM---- 716
LT F + + +G I FYAPWCG C+ AP +E L++
Sbjct: 313 LAAEPEADKGTVLALTENNFDDTIAEGIT--FIKFYAPWCGHCKTLAPTWEELSKKEFPG 370
Query: 717 IKGKVKAGKVDCQAYAQTCQKAGIRAYPTVKFY 749
+ G VK +VDC A C K +R YPT+ +
Sbjct: 371 LAG-VKIAEVDCTAERNICSKYSVRGYPTLLLF 402
Score = 101 bits (251), Expect = 3e-21
Identities = 76/313 (24%), Positives = 139/313 (44%), Gaps = 63/313 (20%)
Query: 391 LKNDHIQVGRFDCSSAPDICSNLYVF-QPSLAVFK-GQGTKEYEIHHGKKILYDILAFAK 448
+++ + V + DC++ D+CS V P+L +FK GQ +Y+ G + + +
Sbjct: 109 MEDAKVYVAKVDCTAHSDVCSAQGVRGYPTLKLFKPGQEAVKYQ---GPRDFQTLENWML 165
Query: 449 ESVNSHVTTLGPQNFPANDKE--------------------PWLVDFFAPWCPPCRALLP 488
+++N T P+ P + E + FFAPWC C+AL P
Sbjct: 166 QTLNEEPVTPEPEVEPPSAPELKQGLYELSASNFELHVAQGDHFIKFFAPWCGHCKALAP 225
Query: 489 ELRR-ASNLLYGQ-LKFGTLDCTVHEGLCNMYNIQAYPTTVVFNQSN-IHEYEGHHSAEQ 545
+ A L + + +K G +DCT H LC+ ++ YPT + F + +Y+G E
Sbjct: 226 TWEQLALGLEHSETVKIGKVDCTQHYELCSGNQVRGYPTLLWFRDGKKVDQYKGKRDLES 285
Query: 546 ILEFIE-----------DLMNPS---------------VVSLTPTTFNELVTQRKHNEVW 579
+ E++E + + PS V++LT F++ + + +
Sbjct: 286 LREYVESQLQRTETGATETVTPSEAPVLAAEPEADKGTVLALTENNFDDTIAEG----IT 341
Query: 580 MVDFYSPWCHPCQVLMPEWKRMA-RTLTGL--INVGSIDCQQYHSFCAQENVQRYPEIRF 636
+ FY+PWC C+ L P W+ ++ + GL + + +DC + C++ +V+ YP +
Sbjct: 342 FIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVDCTAERNICSKYSVRGYPTLLL 401
Query: 637 FPPKSNKAYHYHS 649
F + K HS
Sbjct: 402 F--RGGKKVSEHS 412
Score = 91.7 bits (226), Expect = 2e-18
Identities = 60/207 (28%), Positives = 90/207 (43%), Gaps = 32/207 (15%)
Query: 568 ELVTQRKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTLTGL----INVGSIDCQQYHSFC 623
++ T + V F++PWC CQ L P W + + + V +DC + C
Sbjct: 69 DMFTHGIQSAAHFVMFFAPWCGHCQRLQPTWNDLGDKYNSMEDAKVYVAKVDCTAHSDVC 128
Query: 624 AQENVQRYPEIRFFPPKSNKAYHYHSYNGWNRDAYSLRIWGLGFL--------PQVSTDL 675
+ + V+ YP ++ F P Y G RD +L W L L P+V
Sbjct: 129 SAQGVRGYPTLKLFKPGQEAV----KYQG-PRDFQTLENWMLQTLNEEPVTPEPEVEPPS 183
Query: 676 TPQ-----------TFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKGK--VK 722
P+ F V QG + I F+APWCG C+ AP +E LA ++ VK
Sbjct: 184 APELKQGLYELSASNFELHVAQGDHF--IKFFAPWCGHCKALAPTWEQLALGLEHSETVK 241
Query: 723 AGKVDCQAYAQTCQKAGIRAYPTVKFY 749
GKVDC + + C +R YPT+ ++
Sbjct: 242 IGKVDCTQHYELCSGNQVRGYPTLLWF 268
Score = 75.5 bits (184), Expect = 2e-13
Identities = 38/111 (34%), Positives = 58/111 (52%), Gaps = 4/111 (3%)
Query: 127 DDPEIITLERREFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFA-KEVDGL--LRIGA 183
D ++ L FD + G + F+ FY+P C HC LAPTW + + KE GL ++I
Sbjct: 320 DKGTVLALTENNFDDTIAEG-ITFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAE 378
Query: 184 VNCGDDRMLCRMKGVNSYPSLFIFRSGMAPVKYHGDRSKESLVSFAMQHVR 234
V+C +R +C V YP+L +FR G ++ G R +SL F + +
Sbjct: 379 VDCTAERNICSKYSVRGYPTLLLFRGGKKVSEHSGGRDLDSLHRFVLSQAK 429
Score = 68.6 bits (166), Expect = 2e-11
Identities = 58/201 (28%), Positives = 81/201 (40%), Gaps = 29/201 (14%)
Query: 134 LERREFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFAK--EVDGLLRIGAVNCGDDRM 191
L F+ V G+ F+ F++P C HC LAPTW A E ++IG V+C
Sbjct: 194 LSASNFELHVAQGD-HFIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYE 252
Query: 192 LCRMKGVNSYPSLFIFRSGMAPVKYHGDRSKESL---VSFAMQHVRSTVTELWTGNFV-- 246
LC V YP+L FR G +Y G R ESL V +Q + TE T +
Sbjct: 253 LCSGNQVRGYPTLLWFRDGKKVDQYKGKRDLESLREYVESQLQRTETGATETVTPSEAPV 312
Query: 247 -----------------NSIQTAFAAGIGWLITFCSKGGDCLT-SQTRLRLSGM-LDGL- 286
N+ A GI ++ + G C T + T LS GL
Sbjct: 313 LAAEPEADKGTVLALTENNFDDTIAEGITFIKFYAPWCGHCKTLAPTWEELSKKEFPGLA 372
Query: 287 -VNVGWMDCATQDNLCKSLDI 306
V + +DC + N+C +
Sbjct: 373 GVKIAEVDCTAERNICSKYSV 393
Score = 65.5 bits (158), Expect = 2e-10
Identities = 46/174 (26%), Positives = 74/174 (42%), Gaps = 22/174 (12%)
Query: 150 FVNFYSPGCSHCHDLAPTWRDFAKEV----DGLLRIGAVNCGDDRMLCRMKGVNSYPSLF 205
FV F++P C HC L PTW D + D + + V+C +C +GV YP+L
Sbjct: 81 FVMFFAPWCGHCQRLQPTWNDLGDKYNSMEDAKVYVAKVDCTAHSDVCSAQGVRGYPTLK 140
Query: 206 IFRSGMAPVKYHGDRSKESLVSFAMQHVRS------------TVTELWTGNF---VNSIQ 250
+F+ G VKY G R ++L ++ +Q + + EL G + ++ +
Sbjct: 141 LFKPGQEAVKYQGPRDFQTLENWMLQTLNEEPVTPEPEVEPPSAPELKQGLYELSASNFE 200
Query: 251 TAFAAGIGWLITFCSKGGDC---LTSQTRLRLSGMLDGLVNVGWMDCATQDNLC 301
A G ++ F G C + +L L V +G +DC LC
Sbjct: 201 LHVAQGDHFIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYELC 254
>gi|5803121 protein disulfide isomerase A5 [Homo sapiens]
Length = 519
Score = 111 bits (277), Expect = 3e-24
Identities = 88/361 (24%), Positives = 166/361 (45%), Gaps = 44/361 (12%)
Query: 467 DKEPWLVDFFAPWCPPCRALLPELRRASNLLYGQLKFGTLD--CTVHEGLCNMYNIQAYP 524
+++P L+ F+APWC C+ ++P ++A+ L G ++ + E + Y+++ +P
Sbjct: 169 EEKPLLIMFYAPWCSMCKRMMPHFQKAATQLRGHAVLAGMNVYSSEFENIKEEYSVRGFP 228
Query: 525 TTVVFNQSN-IHEYEGHHS-AEQILEFIEDLMNP--------------SVVSLTPTTFNE 568
T F + + +Y+ + S AE I+E++++ P SV LT F++
Sbjct: 229 TICYFEKGRFLFQYDNYGSTAEDIVEWLKNPQPPQPQVPETPWADEGGSVYHLTDEDFDQ 288
Query: 569 LVTQRKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTLTGLIN----VGSIDCQQYHSFCA 624
V ++H+ V +V F++PWC C+ + PE+++ A L G + + ++D +
Sbjct: 289 FV--KEHSSV-LVMFHAPWCGHCKKMKPEFEKAAEALHGEADSSGVLAAVDATVNKALAE 345
Query: 625 QENVQRYPEIRFFPPKSNKAYHY------HSYNGWNRDAYSLRIWGLGFLPQVST--DLT 676
+ ++ +P +++F K+ + Y + W ++ + + Q ++ L
Sbjct: 346 RFHISEFPTLKYF--KNGEKYAVPVLRTKKKFLEWMQNPEAPPPPEPTWEEQQTSVLHLV 403
Query: 677 PQTFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKG--KVKAGKVDC--QAYA 732
F E L+ K H ++ FYAPWC C+ P F A K K+ VDC
Sbjct: 404 GDNFRE-TLKKKKHTLVMFYAPWCPHCKKVIPHFTATADAFKDDRKIACAAVDCVKDKNQ 462
Query: 733 QTCQKAGIRAYPTVKFYFYERAKRNFQEEQINTRDAKAIAALISEKLETLRNQGKRNKDE 792
CQ+ ++ YPT +Y Y + + ++ I AL E L GK+ K+E
Sbjct: 463 DLCQQEAVKGYPTFHYYHYGKFAEKYDSDRTELGFTNYIRALREGDHERL---GKK-KEE 518
Query: 793 L 793
L
Sbjct: 519 L 519
Score = 68.2 bits (165), Expect = 3e-11
Identities = 56/242 (23%), Positives = 102/242 (42%), Gaps = 32/242 (13%)
Query: 536 EYEGHHSAEQILEFIEDLMNPSVVSLTPTT-----------FNELVTQRKHNEVWMVDFY 584
EY + + I+ F++D P + P F L+ +K + ++ FY
Sbjct: 121 EYNRAVTFKSIVAFLKDPKGPPLWEEDPGAKDVVHLDSEKDFRRLL--KKEEKPLLIMFY 178
Query: 585 SPWCHPCQVLMPEWKRMARTLTGLINVGSIDC--QQYHSFCAQENVQRYPEIRFFPPKSN 642
+PWC C+ +MP +++ A L G + ++ ++ + + +V+ +P I +F K
Sbjct: 179 APWCSMCKRMMPHFQKAATQLRGHAVLAGMNVYSSEFENIKEEYSVRGFPTICYFE-KGR 237
Query: 643 KAYHYHSYNGWNRDAYSLRIWGLGFLPQVSTD-----------LTPQTFSEKVLQGKNHW 691
+ Y +Y D PQV LT + F + V + +
Sbjct: 238 FLFQYDNYGSTAEDIVEWLKNPQPPQPQVPETPWADEGGSVYHLTDEDFDQFVKEHSSVL 297
Query: 692 VIDFYAPWCGPCQNFAPEFELLARMIKGKVKA----GKVDCQAYAQTCQKAGIRAYPTVK 747
V+ F+APWCG C+ PEFE A + G+ + VD ++ I +PT+K
Sbjct: 298 VM-FHAPWCGHCKKMKPEFEKAAEALHGEADSSGVLAAVDATVNKALAERFHISEFPTLK 356
Query: 748 FY 749
++
Sbjct: 357 YF 358
Score = 43.1 bits (100), Expect = 0.001
Identities = 24/82 (29%), Positives = 38/82 (46%), Gaps = 4/82 (4%)
Query: 151 VNFYSPGCSHCHDLAPTWRDFAKEV--DGLLRIGAVNCGDDRM--LCRMKGVNSYPSLFI 206
V FY+P C HC + P + A D + AV+C D+ LC+ + V YP+
Sbjct: 419 VMFYAPWCPHCKKVIPHFTATADAFKDDRKIACAAVDCVKDKNQDLCQQEAVKGYPTFHY 478
Query: 207 FRSGMAPVKYHGDRSKESLVSF 228
+ G KY DR++ ++
Sbjct: 479 YHYGKFAEKYDSDRTELGFTNY 500
Score = 38.1 bits (87), Expect = 0.032
Identities = 22/89 (24%), Positives = 40/89 (44%), Gaps = 4/89 (4%)
Query: 126 DDDPEIITLERREFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFAK----EVDGLLRI 181
D+ + L +FD V V F++P C HC + P + A+ E D +
Sbjct: 273 DEGGSVYHLTDEDFDQFVKEHSSVLVMFHAPWCGHCKKMKPEFEKAAEALHGEADSSGVL 332
Query: 182 GAVNCGDDRMLCRMKGVNSYPSLFIFRSG 210
AV+ ++ L ++ +P+L F++G
Sbjct: 333 AAVDATVNKALAERFHISEFPTLKYFKNG 361
>gi|224493972 thioredoxin domain containing 5 isoform 3 [Homo
sapiens]
Length = 324
Score = 107 bits (266), Expect = 6e-23
Identities = 76/296 (25%), Positives = 123/296 (41%), Gaps = 64/296 (21%)
Query: 506 LDCTVHEGLCNMYNIQAYPTTVVFNQSN-IHEYEGHHSAEQILEFIEDLMNPSVVS---- 560
+DCT H +C+ ++ YPT +F +Y+G + + ++ +N V+
Sbjct: 11 VDCTAHSDVCSAQGVRGYPTLKLFKPGQEAVKYQGPRDFQTLENWMLQTLNEEPVTPEPE 70
Query: 561 ---------------LTPTTFNELVTQRKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTL 605
L+ + F V Q H + F++PWC C+ L P W+++A L
Sbjct: 71 VEPPSAPELKQGLYELSASNFELHVAQGDH----FIKFFAPWCGHCKALAPTWEQLALGL 126
Query: 606 --TGLINVGSIDCQQYHSFCAQENVQRYPEIRFFPPKSNKAYHYHSYNGWNRDAYSLRIW 663
+ + +G +DC Q++ C+ V+ YP + +F Y G RD SLR +
Sbjct: 127 EHSETVKIGKVDCTQHYELCSGNQVRGYPTLLWF----RDGKKVDQYKG-KRDLESLREY 181
Query: 664 GLGFLPQVSTD--------------------------LTPQTFSEKVLQGKNHWVIDFYA 697
L + T LT F + + +G I FYA
Sbjct: 182 VESQLQRTETGATETVTPSEAPVLAAEPEADKGTVLALTENNFDDTIAEGITF--IKFYA 239
Query: 698 PWCGPCQNFAPEFELLARM----IKGKVKAGKVDCQAYAQTCQKAGIRAYPTVKFY 749
PWCG C+ AP +E L++ + G VK +VDC A C K +R YPT+ +
Sbjct: 240 PWCGHCKTLAPTWEELSKKEFPGLAG-VKIAEVDCTAERNICSKYSVRGYPTLLLF 294
Score = 101 bits (251), Expect = 3e-21
Identities = 76/313 (24%), Positives = 139/313 (44%), Gaps = 63/313 (20%)
Query: 391 LKNDHIQVGRFDCSSAPDICSNLYVF-QPSLAVFK-GQGTKEYEIHHGKKILYDILAFAK 448
+++ + V + DC++ D+CS V P+L +FK GQ +Y+ G + + +
Sbjct: 1 MEDAKVYVAKVDCTAHSDVCSAQGVRGYPTLKLFKPGQEAVKYQ---GPRDFQTLENWML 57
Query: 449 ESVNSHVTTLGPQNFPANDKE--------------------PWLVDFFAPWCPPCRALLP 488
+++N T P+ P + E + FFAPWC C+AL P
Sbjct: 58 QTLNEEPVTPEPEVEPPSAPELKQGLYELSASNFELHVAQGDHFIKFFAPWCGHCKALAP 117
Query: 489 ELRR-ASNLLYGQ-LKFGTLDCTVHEGLCNMYNIQAYPTTVVFNQSN-IHEYEGHHSAEQ 545
+ A L + + +K G +DCT H LC+ ++ YPT + F + +Y+G E
Sbjct: 118 TWEQLALGLEHSETVKIGKVDCTQHYELCSGNQVRGYPTLLWFRDGKKVDQYKGKRDLES 177
Query: 546 ILEFIE-----------DLMNPS---------------VVSLTPTTFNELVTQRKHNEVW 579
+ E++E + + PS V++LT F++ + + +
Sbjct: 178 LREYVESQLQRTETGATETVTPSEAPVLAAEPEADKGTVLALTENNFDDTIAEG----IT 233
Query: 580 MVDFYSPWCHPCQVLMPEWKRMA-RTLTGL--INVGSIDCQQYHSFCAQENVQRYPEIRF 636
+ FY+PWC C+ L P W+ ++ + GL + + +DC + C++ +V+ YP +
Sbjct: 234 FIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVDCTAERNICSKYSVRGYPTLLL 293
Query: 637 FPPKSNKAYHYHS 649
F + K HS
Sbjct: 294 F--RGGKKVSEHS 304
Score = 75.5 bits (184), Expect = 2e-13
Identities = 38/111 (34%), Positives = 58/111 (52%), Gaps = 4/111 (3%)
Query: 127 DDPEIITLERREFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFA-KEVDGL--LRIGA 183
D ++ L FD + G + F+ FY+P C HC LAPTW + + KE GL ++I
Sbjct: 212 DKGTVLALTENNFDDTIAEG-ITFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAE 270
Query: 184 VNCGDDRMLCRMKGVNSYPSLFIFRSGMAPVKYHGDRSKESLVSFAMQHVR 234
V+C +R +C V YP+L +FR G ++ G R +SL F + +
Sbjct: 271 VDCTAERNICSKYSVRGYPTLLLFRGGKKVSEHSGGRDLDSLHRFVLSQAK 321
Score = 72.4 bits (176), Expect = 2e-12
Identities = 49/162 (30%), Positives = 72/162 (44%), Gaps = 28/162 (17%)
Query: 609 INVGSIDCQQYHSFCAQENVQRYPEIRFFPPKSNKAYHYHSYNGWNRDAYSLRIWGLGFL 668
+ V +DC + C+ + V+ YP ++ F P Y G RD +L W L L
Sbjct: 6 VYVAKVDCTAHSDVCSAQGVRGYPTLKLFKPGQEAV----KYQG-PRDFQTLENWMLQTL 60
Query: 669 --------PQVSTDLTPQ-----------TFSEKVLQGKNHWVIDFYAPWCGPCQNFAPE 709
P+V P+ F V QG + I F+APWCG C+ AP
Sbjct: 61 NEEPVTPEPEVEPPSAPELKQGLYELSASNFELHVAQGDHF--IKFFAPWCGHCKALAPT 118
Query: 710 FELLARMIKGK--VKAGKVDCQAYAQTCQKAGIRAYPTVKFY 749
+E LA ++ VK GKVDC + + C +R YPT+ ++
Sbjct: 119 WEQLALGLEHSETVKIGKVDCTQHYELCSGNQVRGYPTLLWF 160
Score = 68.6 bits (166), Expect = 2e-11
Identities = 58/201 (28%), Positives = 81/201 (40%), Gaps = 29/201 (14%)
Query: 134 LERREFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFAK--EVDGLLRIGAVNCGDDRM 191
L F+ V G+ F+ F++P C HC LAPTW A E ++IG V+C
Sbjct: 86 LSASNFELHVAQGD-HFIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYE 144
Query: 192 LCRMKGVNSYPSLFIFRSGMAPVKYHGDRSKESL---VSFAMQHVRSTVTELWTGNFV-- 246
LC V YP+L FR G +Y G R ESL V +Q + TE T +
Sbjct: 145 LCSGNQVRGYPTLLWFRDGKKVDQYKGKRDLESLREYVESQLQRTETGATETVTPSEAPV 204
Query: 247 -----------------NSIQTAFAAGIGWLITFCSKGGDCLT-SQTRLRLSGM-LDGL- 286
N+ A GI ++ + G C T + T LS GL
Sbjct: 205 LAAEPEADKGTVLALTENNFDDTIAEGITFIKFYAPWCGHCKTLAPTWEELSKKEFPGLA 264
Query: 287 -VNVGWMDCATQDNLCKSLDI 306
V + +DC + N+C +
Sbjct: 265 GVKIAEVDCTAERNICSKYSV 285
Score = 41.2 bits (95), Expect = 0.004
Identities = 34/144 (23%), Positives = 59/144 (40%), Gaps = 18/144 (12%)
Query: 176 DGLLRIGAVNCGDDRMLCRMKGVNSYPSLFIFRSGMAPVKYHGDRSKESLVSFAMQHVRS 235
D + + V+C +C +GV YP+L +F+ G VKY G R ++L ++ +Q +
Sbjct: 3 DAKVYVAKVDCTAHSDVCSAQGVRGYPTLKLFKPGQEAVKYQGPRDFQTLENWMLQTLNE 62
Query: 236 ------------TVTELWTGNF---VNSIQTAFAAGIGWLITFCSKGGDC---LTSQTRL 277
+ EL G + ++ + A G ++ F G C + +L
Sbjct: 63 EPVTPEPEVEPPSAPELKQGLYELSASNFELHVAQGDHFIKFFAPWCGHCKALAPTWEQL 122
Query: 278 RLSGMLDGLVNVGWMDCATQDNLC 301
L V +G +DC LC
Sbjct: 123 ALGLEHSETVKIGKVDCTQHYELC 146
Score = 38.1 bits (87), Expect = 0.032
Identities = 15/34 (44%), Positives = 20/34 (58%)
Query: 716 MIKGKVKAGKVDCQAYAQTCQKAGIRAYPTVKFY 749
M KV KVDC A++ C G+R YPT+K +
Sbjct: 1 MEDAKVYVAKVDCTAHSDVCSAQGVRGYPTLKLF 34
>gi|56687498 DnaJ (Hsp40) homolog, subfamily C, member 16 [Homo
sapiens]
Length = 782
Score = 107 bits (266), Expect = 6e-23
Identities = 79/254 (31%), Positives = 124/254 (48%), Gaps = 35/254 (13%)
Query: 19 LCFLIVYMAILVGTDQDFYSLLGVSKTASSREIRQAFKKLALKLHPDKNPNNPNAHGDFL 78
L L++ + IL D D Y +LGVS+TAS +I++A+KKLA + HPDKN +P A F+
Sbjct: 13 LIVLVLILQILSALDFDPYRVLGVSRTASQADIKKAYKKLAREWHPDKN-KDPGAEDKFI 71
Query: 79 KINRAYEVLKDEDLRKKYDKYGEKGLEDNQG----GQYESWNYYRYDFGIYDDDPEI--- 131
+I++AYE+L +E+ R YD+YG+ G +NQG Q + + + Y D+
Sbjct: 72 QISKAYEILSNEEKRSNYDQYGDAG--ENQGYQKQQQQREYRFRHFHENFYFDESFFHFP 129
Query: 132 ITLERRE---------FDAAVNS------GELWFVNFYSPGCSHCHDLAPTWRDFAKEVD 176
ERR+ F VN + + + S C C + P W++ +E++
Sbjct: 130 FNSERRDSIDEKYLLHFSHYVNEVVPDSFKKPYLIKITSDWCFSCIHIEPVWKEVIQELE 189
Query: 177 GL-LRIGAVNCGDDRMLCRMKGVNSYPSLFIFRSGMAPVKYHGDRSKESLVSFAMQHVRS 235
L + IG V+ G +R L G +S PS+ +G +H +E+L R
Sbjct: 190 ELGVGIGVVHAGYERRLAHHLGAHSTPSILGIINGKISF-FHNAVVRENL--------RQ 240
Query: 236 TVTELWTGNFVNSI 249
V L GN V +
Sbjct: 241 FVESLLPGNLVEKV 254
>gi|7706495 DnaJ (Hsp40) homolog, subfamily B, member 11 precursor
[Homo sapiens]
Length = 358
Score = 102 bits (253), Expect = 2e-21
Identities = 47/105 (44%), Positives = 75/105 (71%), Gaps = 1/105 (0%)
Query: 20 CFLIVYMAILVGTDQDFYSLLGVSKTASSREIRQAFKKLALKLHPDKNPNNPNAHGDFLK 79
C L++Y+ V +DFY +LGV ++AS ++I++A++KLAL+LHPD+NP++P A F
Sbjct: 10 CLLLLYLIGAVIAGRDFYKILGVPRSASIKDIKKAYRKLALQLHPDRNPDDPQAQEKFQD 69
Query: 80 INRAYEVLKDEDLRKKYDKYGEKGLED-NQGGQYESWNYYRYDFG 123
+ AYEVL D + RK+YD YGE+GL+D +Q + ++++ DFG
Sbjct: 70 LGAAYEVLSDSEKRKQYDTYGEEGLKDGHQSSHGDIFSHFFGDFG 114
>gi|4758304 protein disulfide isomerase A4 [Homo sapiens]
Length = 645
Score = 94.0 bits (232), Expect = 5e-19
Identities = 53/200 (26%), Positives = 100/200 (50%), Gaps = 19/200 (9%)
Query: 462 NFPANDKEPWLVDFFAPWCPPCRALLPELRRASNLLYGQ---LKFGTLDCTVHEGLCNMY 518
NF A DK+ L++F+APWC C+ PE + +N+L + + +D T L + +
Sbjct: 74 NFVA-DKDTVLLEFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDATSASVLASRF 132
Query: 519 NIQAYPTTVVFNQSNIHEYEGHHSAEQILEFIEDLMNPS-------VVSLTPTTFNELVT 571
++ YPT + + +YEG + E+I+ + ++ P + LT F+E+V
Sbjct: 133 DVSGYPTIKILKKGQAVDYEGSRTQEEIVAKVREVSQPDWTPPPEVTLVLTKENFDEVVN 192
Query: 572 QRKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTLTGL---INVGSIDCQQYHSFCAQENV 628
++ +V+FY+PWC C+ L PE+++ A+ L+ I + +D + +V
Sbjct: 193 DA---DIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAETDLAKRFDV 249
Query: 629 QRYPEIRFFPPKSNKAYHYH 648
YP ++ F + + Y Y+
Sbjct: 250 SGYPTLKIF--RKGRPYDYN 267
Score = 83.2 bits (204), Expect = 9e-16
Identities = 63/234 (26%), Positives = 103/234 (44%), Gaps = 22/234 (9%)
Query: 530 NQSNIHEYEGHHSAEQILEFIEDLM---NPSVVSLTPTTFNELVTQRKHNEVWMVDFYSP 586
N+ N E E E E +DL V+ L F+ V + + +++FY+P
Sbjct: 33 NRENAIEDEEEEEEEDDDEEEDDLEVKEENGVLVLNDANFDNFVADK---DTVLLEFYAP 89
Query: 587 WCHPCQVLMPEWKRMARTLTGL---INVGSIDCQQYHSFCAQENVQRYPEIRFFPPKSNK 643
WC C+ PE++++A L I V ID ++ +V YP I+ K +
Sbjct: 90 WCGHCKQFAPEYEKIANILKDKDPPIPVAKIDATSASVLASRFDVSGYPTIKIL--KKGQ 147
Query: 644 AYHYHSYNGWNRDAYSLRI-----WGLGFLPQVSTDLTPQTFSEKVLQGKNHWVIDFYAP 698
A Y +R W P+V+ LT + F E V+ + +++FYAP
Sbjct: 148 AVDYEGSRTQEEIVAKVREVSQPDWTPP--PEVTLVLTKENFDE-VVNDADIILVEFYAP 204
Query: 699 WCGPCQNFAPEFELLARMIKGK---VKAGKVDCQAYAQTCQKAGIRAYPTVKFY 749
WCG C+ APE+E A+ + + + KVD A ++ + YPT+K +
Sbjct: 205 WCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAETDLAKRFDVSGYPTLKIF 258
Score = 69.3 bits (168), Expect = 1e-11
Identities = 50/190 (26%), Positives = 87/190 (45%), Gaps = 18/190 (9%)
Query: 382 PELKKLKTLLKNDH--IQVGRFDCSSAPDICSNLYVF-QPSLAVFKGQGTKEYEIHHGKK 438
PE +K+ +LK+ I V + D +SA + S V P++ + K +YE G +
Sbjct: 99 PEYEKIANILKDKDPPIPVAKIDATSASVLASRFDVSGYPTIKILKKGQAVDYE---GSR 155
Query: 439 ILYDILAFAKESVNSHVT-------TLGPQNFP--ANDKEPWLVDFFAPWCPPCRALLPE 489
+I+A +E T L +NF ND + LV+F+APWC C+ L PE
Sbjct: 156 TQEEIVAKVREVSQPDWTPPPEVTLVLTKENFDEVVNDADIILVEFYAPWCGHCKKLAPE 215
Query: 490 LRRASNLLYGQ---LKFGTLDCTVHEGLCNMYNIQAYPTTVVFNQSNIHEYEGHHSAEQI 546
+A+ L + + +D T L +++ YPT +F + ++Y G I
Sbjct: 216 YEKAAKELSKRSPPIPLAKVDATAETDLAKRFDVSGYPTLKIFRKGRPYDYNGPREKYGI 275
Query: 547 LEFIEDLMNP 556
++++ + P
Sbjct: 276 VDYMIEQSGP 285
Score = 65.1 bits (157), Expect = 2e-10
Identities = 38/118 (32%), Positives = 59/118 (50%), Gaps = 5/118 (4%)
Query: 129 PEI-ITLERREFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFAKEVDGL---LRIGAV 184
PE+ + L + FD VN ++ V FY+P C HC LAP + AKE+ + + V
Sbjct: 176 PEVTLVLTKENFDEVVNDADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKV 235
Query: 185 NCGDDRMLCRMKGVNSYPSLFIFRSGMAPVKYHGDRSKESLVSFAMQHVRSTVTELWT 242
+ + L + V+ YP+L IFR G P Y+G R K +V + ++ E+ T
Sbjct: 236 DATAETDLAKRFDVSGYPTLKIFRKG-RPYDYNGPREKYGIVDYMIEQSGPPSKEILT 292
Score = 54.7 bits (130), Expect = 3e-07
Identities = 37/145 (25%), Positives = 65/145 (44%), Gaps = 9/145 (6%)
Query: 101 EKGLEDNQGGQYESWNYYRYDFGIYDDDPEIITLERREFDAAVNSGELWFVNFYSPGCSH 160
E +ED + + E + D + +++ ++ L FD V + + FY+P C H
Sbjct: 35 ENAIEDEEEEEEEDDDEEEDDLEVKEENG-VLVLNDANFDNFVADKDTVLLEFYAPWCGH 93
Query: 161 CHDLAPTWRDFA---KEVDGLLRIGAVNCGDDRMLCRMKGVNSYPSLFIFRSGMAPVKYH 217
C AP + A K+ D + + ++ +L V+ YP++ I + G A V Y
Sbjct: 94 CKQFAPEYEKIANILKDKDPPIPVAKIDATSASVLASRFDVSGYPTIKILKKGQA-VDYE 152
Query: 218 GDRSKESLVSFAMQHVRSTVTELWT 242
G R++E +V+ VR WT
Sbjct: 153 GSRTQEEIVA----KVREVSQPDWT 173
Score = 53.9 bits (128), Expect = 6e-07
Identities = 34/118 (28%), Positives = 57/118 (48%), Gaps = 7/118 (5%)
Query: 678 QTFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKGK--VKAGKVDCQAYAQTC 735
+TF V+ K +I+FYAPWCG C+ P + LA+ KG+ + K+D A
Sbjct: 533 KTFDSIVMDPKKDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIAKMDATANDVPS 592
Query: 736 QKAGIRAYPTVKFYFYERAKRNFQEEQINTRDAKAIAALISEKLETLRNQGKRNKDEL 793
+ + +PT+ ++ K+N + + RD + ++ I E L R K+EL
Sbjct: 593 DRYKVEGFPTI-YFAPSGDKKNPVKFEGGDRDLEHLSKFIEEHATKL----SRTKEEL 645
Score = 43.1 bits (100), Expect = 0.001
Identities = 27/87 (31%), Positives = 41/87 (47%), Gaps = 5/87 (5%)
Query: 151 VNFYSPGCSHCHDLAPTWRDFAKEVDGL--LRIGAVNCGDDRMLCRMKGVNSYPSLFIFR 208
+ FY+P C HC L P + AK+ G L I ++ + + V +P+++
Sbjct: 548 IEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIAKMDATANDVPSDRYKVEGFPTIYFAP 607
Query: 209 SG--MAPVKYH-GDRSKESLVSFAMQH 232
SG PVK+ GDR E L F +H
Sbjct: 608 SGDKKNPVKFEGGDRDLEHLSKFIEEH 634
Score = 42.4 bits (98), Expect = 0.002
Identities = 26/92 (28%), Positives = 47/92 (51%), Gaps = 8/92 (8%)
Query: 468 KEPWLVDFFAPWCPPCRALLPELRRASNLLYGQ--LKFGTLDCTVHEGLCNMYNIQAYPT 525
K+ L++F+APWC C+ L P + GQ L +D T ++ + Y ++ +P
Sbjct: 543 KKDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIAKMDATANDVPSDRYKVEGFP- 601
Query: 526 TVVF----NQSNIHEYE-GHHSAEQILEFIED 552
T+ F ++ N ++E G E + +FIE+
Sbjct: 602 TIYFAPSGDKKNPVKFEGGDRDLEHLSKFIEE 633
Score = 37.0 bits (84), Expect = 0.072
Identities = 24/94 (25%), Positives = 44/94 (46%), Gaps = 6/94 (6%)
Query: 565 TFNELVTQRKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTLTGL--INVGSIDCQQYHSF 622
TF+ +V K + +++FY+PWC C+ L P + +A+ G + + +D
Sbjct: 534 TFDSIVMDPKKDV--LIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIAKMDATANDVP 591
Query: 623 CAQENVQRYPEIRFFPPKSNKAYHYHSYNGWNRD 656
+ V+ +P I F P K + + G +RD
Sbjct: 592 SDRYKVEGFPTIYFAPSGDKK--NPVKFEGGDRD 623
>gi|6631085 DnaJ (Hsp40) homolog, subfamily B, member 4 [Homo
sapiens]
Length = 337
Score = 81.6 bits (200), Expect = 3e-15
Identities = 39/89 (43%), Positives = 57/89 (64%), Gaps = 1/89 (1%)
Query: 34 QDFYSLLGVSKTASSREIRQAFKKLALKLHPDKNPNNPNAHGDFLKINRAYEVLKDEDLR 93
+D+Y +LG+ K AS +I++A++K ALK HPDKN +P A F ++ AYEVL D R
Sbjct: 3 KDYYCILGIEKGASDEDIKKAYRKQALKFHPDKN-KSPQAEEKFKEVAEAYEVLSDPKKR 61
Query: 94 KKYDKYGEKGLEDNQGGQYESWNYYRYDF 122
+ YD++GE+GL+ GG +RY F
Sbjct: 62 EIYDQFGEEGLKGGAGGTDGQGGTFRYTF 90
>gi|17388799 DnaJ (Hsp40) homolog, subfamily B, member 6 isoform a
[Homo sapiens]
Length = 326
Score = 79.7 bits (195), Expect = 1e-14
Identities = 41/95 (43%), Positives = 57/95 (60%), Gaps = 1/95 (1%)
Query: 35 DFYSLLGVSKTASSREIRQAFKKLALKLHPDKNP-NNPNAHGDFLKINRAYEVLKDEDLR 93
D+Y +LGV + AS +I++A++KLALK HPDKNP N A F ++ AYEVL D R
Sbjct: 3 DYYEVLGVQRHASPEDIKKAYRKLALKWHPDKNPENKEEAERKFKQVAEAYEVLSDAKKR 62
Query: 94 KKYDKYGEKGLEDNQGGQYESWNYYRYDFGIYDDD 128
YDKYG++GL GG + + + F + D
Sbjct: 63 DIYDKYGKEGLNGGGGGGSHFDSPFEFGFTFRNPD 97
>gi|4885495 DnaJ (Hsp40) homolog, subfamily B, member 6 isoform b
[Homo sapiens]
Length = 241
Score = 79.7 bits (195), Expect = 1e-14
Identities = 41/95 (43%), Positives = 57/95 (60%), Gaps = 1/95 (1%)
Query: 35 DFYSLLGVSKTASSREIRQAFKKLALKLHPDKNP-NNPNAHGDFLKINRAYEVLKDEDLR 93
D+Y +LGV + AS +I++A++KLALK HPDKNP N A F ++ AYEVL D R
Sbjct: 3 DYYEVLGVQRHASPEDIKKAYRKLALKWHPDKNPENKEEAERKFKQVAEAYEVLSDAKKR 62
Query: 94 KKYDKYGEKGLEDNQGGQYESWNYYRYDFGIYDDD 128
YDKYG++GL GG + + + F + D
Sbjct: 63 DIYDKYGKEGLNGGGGGGSHFDSPFEFGFTFRNPD 97
>gi|205360840 DnaJ (Hsp40) homolog, subfamily A, member 3 isoform 2
[Homo sapiens]
Length = 453
Score = 79.3 bits (194), Expect = 1e-14
Identities = 36/82 (43%), Positives = 52/82 (63%)
Query: 34 QDFYSLLGVSKTASSREIRQAFKKLALKLHPDKNPNNPNAHGDFLKINRAYEVLKDEDLR 93
+D+Y +LGV + AS +EI++A+ +LA K HPD N ++P A F ++ AYEVL DE R
Sbjct: 92 EDYYQILGVPRNASQKEIKKAYYQLAKKYHPDTNKDDPKAKEKFSQLAEAYEVLSDEVKR 151
Query: 94 KKYDKYGEKGLEDNQGGQYESW 115
K+YD YG G + G S+
Sbjct: 152 KQYDAYGSAGFDPGASGSQHSY 173
>gi|205360838 DnaJ (Hsp40) homolog, subfamily A, member 3 isoform 1
[Homo sapiens]
Length = 480
Score = 79.3 bits (194), Expect = 1e-14
Identities = 36/82 (43%), Positives = 52/82 (63%)
Query: 34 QDFYSLLGVSKTASSREIRQAFKKLALKLHPDKNPNNPNAHGDFLKINRAYEVLKDEDLR 93
+D+Y +LGV + AS +EI++A+ +LA K HPD N ++P A F ++ AYEVL DE R
Sbjct: 92 EDYYQILGVPRNASQKEIKKAYYQLAKKYHPDTNKDDPKAKEKFSQLAEAYEVLSDEVKR 151
Query: 94 KKYDKYGEKGLEDNQGGQYESW 115
K+YD YG G + G S+
Sbjct: 152 KQYDAYGSAGFDPGASGSQHSY 173
>gi|9558755 DnaJ (Hsp40) homolog, subfamily B, member 9 [Homo
sapiens]
Length = 223
Score = 79.0 bits (193), Expect = 2e-14
Identities = 44/110 (40%), Positives = 63/110 (57%), Gaps = 4/110 (3%)
Query: 19 LCFLIVYMAILVGTDQDFYSLLGVSKTASSREIRQAFKKLALKLHPDKNPNNPNAHGDFL 78
+C L++ IL + +Y +LGV K+AS R+I++AF KLA+K HPDKN +P+A F
Sbjct: 12 ICILMITELILAS--KSYYDILGVPKSASERQIKKAFHKLAMKYHPDKN-KSPDAEAKFR 68
Query: 79 KINRAYEVLKDEDLRKKYDKYGEKGLEDNQGGQYESWNYYRYDFGIYDDD 128
+I AYE L D + RK+YD G + GQ S + + F DD
Sbjct: 69 EIAEAYETLSDANRRKEYDTLGHSAFTSGK-GQRGSGSSFEQSFNFNFDD 117
>gi|201862587 DnaJ (Hsp40) homolog, subfamily B, member 5 isoform 1
[Homo sapiens]
Length = 420
Score = 78.2 bits (191), Expect = 3e-14
Identities = 39/89 (43%), Positives = 55/89 (61%), Gaps = 1/89 (1%)
Query: 34 QDFYSLLGVSKTASSREIRQAFKKLALKLHPDKNPNNPNAHGDFLKINRAYEVLKDEDLR 93
+D+Y +LG+ A+ EI++A++K+ALK HPDKN PNA F +I AY+VL D R
Sbjct: 75 KDYYKILGIPSGANEDEIKKAYRKMALKYHPDKN-KEPNAEEKFKEIAEAYDVLSDPKKR 133
Query: 94 KKYDKYGEKGLEDNQGGQYESWNYYRYDF 122
YD+YGE+GL+ G S + Y F
Sbjct: 134 GLYDQYGEEGLKTGGGTSGGSSGSFHYTF 162
>gi|201862518 DnaJ (Hsp40) homolog, subfamily B, member 5 isoform 2
[Homo sapiens]
Length = 382
Score = 78.2 bits (191), Expect = 3e-14
Identities = 39/89 (43%), Positives = 55/89 (61%), Gaps = 1/89 (1%)
Query: 34 QDFYSLLGVSKTASSREIRQAFKKLALKLHPDKNPNNPNAHGDFLKINRAYEVLKDEDLR 93
+D+Y +LG+ A+ EI++A++K+ALK HPDKN PNA F +I AY+VL D R
Sbjct: 37 KDYYKILGIPSGANEDEIKKAYRKMALKYHPDKN-KEPNAEEKFKEIAEAYDVLSDPKKR 95
Query: 94 KKYDKYGEKGLEDNQGGQYESWNYYRYDF 122
YD+YGE+GL+ G S + Y F
Sbjct: 96 GLYDQYGEEGLKTGGGTSGGSSGSFHYTF 124
>gi|56549115 DnaJ (Hsp40) homolog, subfamily B, member 5 isoform 3
[Homo sapiens]
Length = 348
Score = 78.2 bits (191), Expect = 3e-14
Identities = 39/89 (43%), Positives = 55/89 (61%), Gaps = 1/89 (1%)
Query: 34 QDFYSLLGVSKTASSREIRQAFKKLALKLHPDKNPNNPNAHGDFLKINRAYEVLKDEDLR 93
+D+Y +LG+ A+ EI++A++K+ALK HPDKN PNA F +I AY+VL D R
Sbjct: 3 KDYYKILGIPSGANEDEIKKAYRKMALKYHPDKN-KEPNAEEKFKEIAEAYDVLSDPKKR 61
Query: 94 KKYDKYGEKGLEDNQGGQYESWNYYRYDF 122
YD+YGE+GL+ G S + Y F
Sbjct: 62 GLYDQYGEEGLKTGGGTSGGSSGSFHYTF 90
>gi|45504382 DnaJ (Hsp40) homolog, subfamily C, member 5 [Homo
sapiens]
Length = 198
Score = 77.8 bits (190), Expect = 4e-14
Identities = 35/71 (49%), Positives = 49/71 (69%)
Query: 34 QDFYSLLGVSKTASSREIRQAFKKLALKLHPDKNPNNPNAHGDFLKINRAYEVLKDEDLR 93
+ Y +LG+ K A+S +I+++++KLALK HPDKNP+NP A F +IN A+ +L D R
Sbjct: 14 ESLYHVLGLDKNATSDDIKKSYRKLALKYHPDKNPDNPEAADKFKEINNAHAILTDATKR 73
Query: 94 KKYDKYGEKGL 104
YDKYG GL
Sbjct: 74 NIYDKYGSLGL 84
>gi|5031741 DnaJ subfamily A member 2 [Homo sapiens]
Length = 412
Score = 76.3 bits (186), Expect = 1e-13
Identities = 39/91 (42%), Positives = 57/91 (62%), Gaps = 3/91 (3%)
Query: 33 DQDFYSLLGVSKTASSREIRQAFKKLALKLHPDKNPNNPNAHGDFLKINRAYEVLKDEDL 92
D Y +LGV AS E+++A++KLA + HPDKNPN A F +I+ AYEVL + +
Sbjct: 6 DTKLYDILGVPPGASENELKKAYRKLAKEYHPDKNPN---AGDKFKEISFAYEVLSNPEK 62
Query: 93 RKKYDKYGEKGLEDNQGGQYESWNYYRYDFG 123
R+ YD+YGE+GL + GG + + + FG
Sbjct: 63 RELYDRYGEQGLREGSGGGGGMDDIFSHIFG 93
>gi|21553335 DnaJ (Hsp40) homolog, subfamily B, member 7 [Homo
sapiens]
Length = 309
Score = 75.9 bits (185), Expect = 1e-13
Identities = 43/106 (40%), Positives = 63/106 (59%), Gaps = 2/106 (1%)
Query: 35 DFYSLLGVSKTASSREIRQAFKKLALKLHPDKNP-NNPNAHGDFLKINRAYEVLKDEDLR 93
D+Y +LG+ + AS +I++A+ K+ALK HPDKNP N A F ++ AYEVL +++ R
Sbjct: 3 DYYEVLGLQRYASPEDIKKAYHKVALKWHPDKNPENKEEAERKFKEVAEAYEVLSNDEKR 62
Query: 94 KKYDKYGEKGLEDNQGGQYESWNYYRYDFGIYDDDPEIITLERREF 139
YDKYG +GL + G ++ Y + F DD + I ER F
Sbjct: 63 DIYDKYGTEGL-NGGGSHFDDECEYGFTFHKPDDVFKEIFHERDPF 107
>gi|29126218 DnaJ (Hsp40) homolog, subfamily C, member 5 beta [Homo
sapiens]
Length = 199
Score = 75.5 bits (184), Expect = 2e-13
Identities = 36/73 (49%), Positives = 49/73 (67%)
Query: 32 TDQDFYSLLGVSKTASSREIRQAFKKLALKLHPDKNPNNPNAHGDFLKINRAYEVLKDED 91
T + Y +LG+ K AS+ EI++ ++KLALK HPDKNP++P A F +IN A+ +L D
Sbjct: 16 TGEALYEILGLHKGASNEEIKKTYRKLALKHHPDKNPDDPAATEKFKEINNAHAILTDIS 75
Query: 92 LRKKYDKYGEKGL 104
R YDKYG GL
Sbjct: 76 KRSIYDKYGSLGL 88
>gi|47777312 DnaJ (Hsp40) homolog, subfamily B, member 3 [Homo
sapiens]
Length = 145
Score = 75.1 bits (183), Expect = 2e-13
Identities = 41/93 (44%), Positives = 53/93 (56%), Gaps = 1/93 (1%)
Query: 35 DFYSLLGVSKTASSREIRQAFKKLALKLHPDKNP-NNPNAHGDFLKINRAYEVLKDEDLR 93
D+Y +L V + ASS I++A++KLALK HPDKNP N A F ++ AYEVL D R
Sbjct: 3 DYYEVLDVPRQASSEAIKKAYRKLALKWHPDKNPENKEEAERRFKQVAEAYEVLSDAKKR 62
Query: 94 KKYDKYGEKGLEDNQGGQYESWNYYRYDFGIYD 126
YD+YGE G E G + + Y F D
Sbjct: 63 DIYDRYGEAGAEGGCTGGRPFEDPFEYVFSFRD 95
>gi|21361657 protein disulfide-isomerase A3 precursor [Homo sapiens]
Length = 505
Score = 73.9 bits (180), Expect = 5e-13
Identities = 44/147 (29%), Positives = 69/147 (46%), Gaps = 7/147 (4%)
Query: 443 ILAFAKESVNSHVTTLGPQNFPANDKEP-----WLVDFFAPWCPPCRALLPELRRASNLL 497
+LA A+ + S V L NF + + LV+FFAPWC C+ L PE A+ L
Sbjct: 15 LLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRL 74
Query: 498 YGQLKFGTLDCTVHEGLCNMYNIQAYPTTVVFNQ-SNIHEYEGHHSAEQILEFIEDLMNP 556
G + +DCT + CN Y + YPT +F Y+G +A+ I+ ++ P
Sbjct: 75 KGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQAGP 134
Query: 557 SVVSL-TPTTFNELVTQRKHNEVWMVD 582
+ V L T F + ++ + + V D
Sbjct: 135 ASVPLRTEEEFKKFISDKDASIVGFFD 161
Score = 72.0 bits (175), Expect = 2e-12
Identities = 31/78 (39%), Positives = 44/78 (56%), Gaps = 2/78 (2%)
Query: 674 DLTPQTFSEKVLQ--GKNHWVIDFYAPWCGPCQNFAPEFELLARMIKGKVKAGKVDCQAY 731
+LT F ++ +++F+APWCG C+ APE+E A +KG V KVDC A
Sbjct: 29 ELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVPLAKVDCTAN 88
Query: 732 AQTCQKAGIRAYPTVKFY 749
TC K G+ YPT+K +
Sbjct: 89 TNTCNKYGVSGYPTLKIF 106
Score = 63.9 bits (154), Expect = 5e-10
Identities = 32/101 (31%), Positives = 53/101 (52%), Gaps = 3/101 (2%)
Query: 130 EIITLERREFDAAVN---SGELWFVNFYSPGCSHCHDLAPTWRDFAKEVDGLLRIGAVNC 186
+++ L F++ ++ S L V F++P C HC LAP + A + G++ + V+C
Sbjct: 26 DVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVPLAKVDC 85
Query: 187 GDDRMLCRMKGVNSYPSLFIFRSGMAPVKYHGDRSKESLVS 227
+ C GV+ YP+L IFR G Y G R+ + +VS
Sbjct: 86 TANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVS 126
Score = 55.8 bits (133), Expect = 1e-07
Identities = 23/80 (28%), Positives = 42/80 (52%)
Query: 558 VVSLTPTTFNELVTQRKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTLTGLINVGSIDCQ 617
V+ LT F ++ + +V+F++PWC C+ L PE++ A L G++ + +DC
Sbjct: 27 VLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVPLAKVDCT 86
Query: 618 QYHSFCAQENVQRYPEIRFF 637
+ C + V YP ++ F
Sbjct: 87 ANTNTCNKYGVSGYPTLKIF 106
Score = 42.4 bits (98), Expect = 0.002
Identities = 29/121 (23%), Positives = 59/121 (48%), Gaps = 12/121 (9%)
Query: 449 ESVNSHVTTLGPQNFPA---NDKEPWLVDFFAPWCPPCRALLPELRRASNLLY--GQLKF 503
ES + V + +NF N+ + L++F+APWC C+ L P+ + L +
Sbjct: 372 ESNDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVI 431
Query: 504 GTLDCTVHEGLCNMYNIQAYPTTVVFNQS----NIHEYEGHHSAEQILEFIE-DLMNPSV 558
+D T ++ + + Y ++ +P T+ F+ + N +YEG + +++ + NP V
Sbjct: 432 AKMDATAND-VPSPYEVRGFP-TIYFSPANKKLNPKKYEGGRELSDFISYLQREATNPPV 489
Query: 559 V 559
+
Sbjct: 490 I 490
Score = 42.0 bits (97), Expect = 0.002
Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 3/73 (4%)
Query: 678 QTFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIK--GKVKAGKVDCQAYAQTC 735
+ F E V +I+FYAPWCG C+N P+++ L + + K+D A
Sbjct: 384 ENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATA-NDVP 442
Query: 736 QKAGIRAYPTVKF 748
+R +PT+ F
Sbjct: 443 SPYEVRGFPTIYF 455
Score = 38.1 bits (87), Expect = 0.032
Identities = 25/89 (28%), Positives = 45/89 (50%), Gaps = 7/89 (7%)
Query: 566 FNELVTQRKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTLTGLIN--VGSIDCQQYHSFC 623
F+E+V N+ +++FY+PWC C+ L P++K + L+ N + +D +
Sbjct: 386 FDEIVNNE--NKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATA-NDVP 442
Query: 624 AQENVQRYPEIRFFPPKSNKAYHYHSYNG 652
+ V+ +P I F P +NK + Y G
Sbjct: 443 SPYEVRGFPTIYFSP--ANKKLNPKKYEG 469
Score = 35.4 bits (80), Expect = 0.21
Identities = 23/107 (21%), Positives = 51/107 (47%), Gaps = 6/107 (5%)
Query: 127 DDPEIITLERREFDAAVNS-GELWFVNFYSPGCSHCHDLAPTWRDFAKEV--DGLLRIGA 183
+D + + FD VN+ + + FY+P C HC +L P +++ +++ D + I
Sbjct: 374 NDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAK 433
Query: 184 VNCGDDRMLCRMKGVNSYPSLFIFRSG--MAPVKYHGDRSKESLVSF 228
++ + + + V +P+++ + + P KY G R +S+
Sbjct: 434 MDATANDVPSPYE-VRGFPTIYFSPANKKLNPKKYEGGRELSDFISY 479
>gi|4504511 DnaJ (Hsp40) homolog, subfamily A, member 1 [Homo
sapiens]
Length = 397
Score = 71.6 bits (174), Expect = 3e-12
Identities = 34/75 (45%), Positives = 50/75 (66%), Gaps = 3/75 (4%)
Query: 36 FYSLLGVSKTASSREIRQAFKKLALKLHPDKNPNNPNAHGDFLKINRAYEVLKDEDLRKK 95
+Y +LGV A+ E+++A++KLALK HPDKNPN F +I++AYEVL D R+
Sbjct: 7 YYDVLGVKPNATQEELKKAYRKLALKYHPDKNPNEGE---KFKQISQAYEVLSDAKKREL 63
Query: 96 YDKYGEKGLEDNQGG 110
YDK GE+ +++ G
Sbjct: 64 YDKGGEQAIKEGGAG 78
>gi|5453690 DnaJ (Hsp40) homolog, subfamily B, member 1 [Homo
sapiens]
Length = 340
Score = 69.7 bits (169), Expect = 1e-11
Identities = 36/96 (37%), Positives = 58/96 (60%), Gaps = 3/96 (3%)
Query: 34 QDFYSLLGVSKTASSREIRQAFKKLALKLHPDKNPNNPNAHGDFLKINRAYEVLKDEDLR 93
+D+Y LG+++ AS EI++A+++ AL+ HPDKN P A F +I AY+VL D R
Sbjct: 3 KDYYQTLGLARGASDEEIKRAYRRQALRYHPDKN-KEPGAEEKFKEIAEAYDVLSDPRKR 61
Query: 94 KKYDKYGEKGLEDN--QGGQYESWNYYRYDFGIYDD 127
+ +D+YGE+GL+ + GG N + + + D
Sbjct: 62 EIFDRYGEEGLKGSGPSGGSGGGANGTSFSYTFHGD 97
>gi|22749377 DnaJ (Hsp40) homolog, subfamily C, member 18 [Homo
sapiens]
Length = 358
Score = 69.7 bits (169), Expect = 1e-11
Identities = 36/86 (41%), Positives = 55/86 (63%), Gaps = 2/86 (2%)
Query: 34 QDFYSLLGVSKTASSREIRQAFKKLALKLHPDKNPNNPNAHGDFLKINRAYEVLKDEDLR 93
+++Y +LGVS+ AS E+++A++KLALK HPDKN P A F I A+ VL + D R
Sbjct: 81 RNYYEILGVSRDASDEELKKAYRKLALKFHPDKN-CAPGATDAFKAIGNAFAVLSNPDKR 139
Query: 94 KKYDKYGEKGLEDNQGGQYESWNYYR 119
+YD+YG++ + + +NYYR
Sbjct: 140 LRYDEYGDEQVTFT-APRARPYNYYR 164
>gi|21361912 DnaJ (Hsp40) homolog, subfamily C, member 1 [Homo
sapiens]
Length = 554
Score = 68.9 bits (167), Expect = 2e-11
Identities = 35/72 (48%), Positives = 49/72 (68%), Gaps = 1/72 (1%)
Query: 35 DFYSLLGVSKTASSREIRQAFKKLALKLHPDKNPNNPNAHGDFLKINRAYEVLKDEDLRK 94
+FY LGV + ASS +IR+A++KL+L LHPDKN + NA F ++ YEVLKD++ R+
Sbjct: 65 NFYQFLGVQQDASSADIRKAYRKLSLTLHPDKN-KDENAETQFRQLVAIYEVLKDDERRQ 123
Query: 95 KYDKYGEKGLED 106
+YD GL D
Sbjct: 124 RYDDILINGLPD 135
>gi|194328760 DnaJ (Hsp40) homolog, subfamily A, member 4 isoform 2
[Homo sapiens]
Length = 397
Score = 68.9 bits (167), Expect = 2e-11
Identities = 34/78 (43%), Positives = 50/78 (64%), Gaps = 3/78 (3%)
Query: 33 DQDFYSLLGVSKTASSREIRQAFKKLALKLHPDKNPNNPNAHGDFLKINRAYEVLKDEDL 92
+ +Y +LGV +AS EI++A++KLALK HPDKNP+ F I++AYEVL D
Sbjct: 4 ETQYYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEGE---KFKLISQAYEVLSDPKK 60
Query: 93 RKKYDKYGEKGLEDNQGG 110
R YD+ GE+ +++ G
Sbjct: 61 RDVYDQGGEQAIKEGGSG 78
>gi|194328758 DnaJ (Hsp40) homolog, subfamily A, member 4 isoform 1
[Homo sapiens]
Length = 426
Score = 68.9 bits (167), Expect = 2e-11
Identities = 34/78 (43%), Positives = 50/78 (64%), Gaps = 3/78 (3%)
Query: 33 DQDFYSLLGVSKTASSREIRQAFKKLALKLHPDKNPNNPNAHGDFLKINRAYEVLKDEDL 92
+ +Y +LGV +AS EI++A++KLALK HPDKNP+ F I++AYEVL D
Sbjct: 33 ETQYYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEGE---KFKLISQAYEVLSDPKK 89
Query: 93 RKKYDKYGEKGLEDNQGG 110
R YD+ GE+ +++ G
Sbjct: 90 RDVYDQGGEQAIKEGGSG 107
>gi|39204547 testis spermatogenesis apoptosis-related protein 6
[Homo sapiens]
Length = 316
Score = 68.2 bits (165), Expect = 3e-11
Identities = 33/72 (45%), Positives = 52/72 (72%), Gaps = 1/72 (1%)
Query: 34 QDFYSLLGVSKTASSREIRQAFKKLALKLHPDKNPNNPNAHGDFLKINRAYEVLKDEDLR 93
QD+YS+LG+++ + +I+QA+++LALK HP K+ N P++ F +I AY+VL D R
Sbjct: 3 QDYYSVLGITRNSEDAQIKQAYRRLALKHHPLKS-NEPSSAEIFRQIAEAYDVLSDPMKR 61
Query: 94 KKYDKYGEKGLE 105
YDK+GE+GL+
Sbjct: 62 GIYDKFGEEGLK 73
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.436
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,119,708
Number of Sequences: 37866
Number of extensions: 1407978
Number of successful extensions: 3036
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 82
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 2704
Number of HSP's gapped (non-prelim): 217
length of query: 793
length of database: 18,247,518
effective HSP length: 110
effective length of query: 683
effective length of database: 14,082,258
effective search space: 9618182214
effective search space used: 9618182214
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.