BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|24234744 semaphorin 6D isoform 5 precursor [Homo sapiens] (597 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|24234744 semaphorin 6D isoform 5 precursor [Homo sapiens] 1229 0.0 gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens] 1184 0.0 gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens] 1180 0.0 gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens] 1177 0.0 gi|24234729 semaphorin 6D isoform 1 precursor [Homo sapiens] 1168 0.0 gi|24234732 semaphorin 6D isoform 6 precursor [Homo sapiens] 976 0.0 gi|11991660 sema domain, transmembrane domain (TM), and cytoplas... 738 0.0 gi|19718780 semaphorin 6B precursor [Homo sapiens] 608 e-174 gi|16306552 semaphorin Y [Homo sapiens] 586 e-167 gi|41406086 semaphorin 3D [Homo sapiens] 315 1e-85 gi|91982767 semaphorin 5B isoform 1 [Homo sapiens] 308 7e-84 gi|5174673 semaphorin 3A precursor [Homo sapiens] 303 3e-82 gi|6912650 semaphorin 3E [Homo sapiens] 298 7e-81 gi|147904700 semaphorin 5A [Homo sapiens] 295 8e-80 gi|188497703 semaphorin 3F [Homo sapiens] 294 2e-79 gi|5454048 semaphorin 3C [Homo sapiens] 288 8e-78 gi|4759092 semaphorin 3B isoform 1 precursor [Homo sapiens] 287 2e-77 gi|54607089 semaphorin 3B isoform 2 precursor [Homo sapiens] 283 3e-76 gi|214010220 semaphorin 4D isoform 2 [Homo sapiens] 281 2e-75 gi|214010218 semaphorin 4D isoform 1 [Homo sapiens] 281 2e-75 gi|157388902 semaphorin 4C [Homo sapiens] 268 1e-71 gi|39777610 semaphorin 4B precursor [Homo sapiens] 261 2e-69 gi|39777608 semaphorin 4B precursor [Homo sapiens] 261 2e-69 gi|9910362 semaphorin sem2 [Homo sapiens] 258 1e-68 gi|21361914 semaphorin B [Homo sapiens] 233 4e-61 gi|19923279 semaphorin W [Homo sapiens] 224 2e-58 gi|28872814 semaphorin 4G [Homo sapiens] 221 1e-57 gi|4504237 semaphorin 7A isoform 1 preproprotein [Homo sapiens] 134 2e-31 gi|225637520 semaphorin 7A isoform 2 preproprotein [Homo sapiens] 133 4e-31 gi|225637524 semaphorin 7A isoform 3 [Homo sapiens] 116 5e-26 >gi|24234744 semaphorin 6D isoform 5 precursor [Homo sapiens] Length = 597 Score = 1229 bits (3179), Expect = 0.0 Identities = 597/597 (100%), Positives = 597/597 (100%) Query: 1 MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQ 60 MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQ Sbjct: 1 MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQ 60 Query: 61 LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHN 120 LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHN Sbjct: 61 LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHN 120 Query: 121 FIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFAD 180 FIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFAD Sbjct: 121 FIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFAD 180 Query: 181 GKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREI 240 GKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREI Sbjct: 181 GKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREI 240 Query: 241 AVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSI 300 AVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSI Sbjct: 241 AVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSI 300 Query: 301 TDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPED 360 TDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPED Sbjct: 301 TDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPED 360 Query: 361 KVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYR 420 KVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYR Sbjct: 361 KVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYR 420 Query: 421 LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAE 480 LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAE Sbjct: 421 LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAE 480 Query: 481 NEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGS 540 NEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGS Sbjct: 481 NEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGS 540 Query: 541 CGRVTPGMLAEGYEQDTEFGNTAHLGDCHDMEVSSSSVTTMVYDGKSSLESPTRWST 597 CGRVTPGMLAEGYEQDTEFGNTAHLGDCHDMEVSSSSVTTMVYDGKSSLESPTRWST Sbjct: 541 CGRVTPGMLAEGYEQDTEFGNTAHLGDCHDMEVSSSSVTTMVYDGKSSLESPTRWST 597 >gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens] Length = 1073 Score = 1184 bits (3063), Expect = 0.0 Identities = 581/600 (96%), Positives = 581/600 (96%), Gaps = 19/600 (3%) Query: 1 MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQ 60 MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQ Sbjct: 1 MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQ 60 Query: 61 LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHN 120 LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHN Sbjct: 61 LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHN 120 Query: 121 FIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFAD 180 FIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFAD Sbjct: 121 FIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFAD 180 Query: 181 GKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREI 240 GKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREI Sbjct: 181 GKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREI 240 Query: 241 AVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSI 300 AVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSI Sbjct: 241 AVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSI 300 Query: 301 TDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPED 360 TDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPED Sbjct: 301 TDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPED 360 Query: 361 KVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYR 420 KVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYR Sbjct: 361 KVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYR 420 Query: 421 LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAE 480 LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAE Sbjct: 421 LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAE 480 Query: 481 NEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGS 540 NEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGS Sbjct: 481 NEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGS 540 Query: 541 CGRVTPGMLAEGYEQDTEFGNTAHLGDCH-------------------DMEVSSSSVTTM 581 CGRVTPGMLAEGYEQDTEFGNTAHLGDCH DMEVSSSSVTTM Sbjct: 541 CGRVTPGMLAEGYEQDTEFGNTAHLGDCHEILPTSTTPDYKIFGGPTSDMEVSSSSVTTM 600 >gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens] Length = 1017 Score = 1180 bits (3052), Expect = 0.0 Identities = 572/588 (97%), Positives = 580/588 (98%) Query: 1 MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQ 60 MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQ Sbjct: 1 MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQ 60 Query: 61 LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHN 120 LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHN Sbjct: 61 LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHN 120 Query: 121 FIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFAD 180 FIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFAD Sbjct: 121 FIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFAD 180 Query: 181 GKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREI 240 GKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREI Sbjct: 181 GKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREI 240 Query: 241 AVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSI 300 AVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSI Sbjct: 241 AVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSI 300 Query: 301 TDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPED 360 TDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPED Sbjct: 301 TDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPED 360 Query: 361 KVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYR 420 KVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYR Sbjct: 361 KVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYR 420 Query: 421 LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAE 480 LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAE Sbjct: 421 LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAE 480 Query: 481 NEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGS 540 NEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGS Sbjct: 481 NEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGS 540 Query: 541 CGRVTPGMLAEGYEQDTEFGNTAHLGDCHDMEVSSSSVTTMVYDGKSS 588 CGRVTPGMLAEGYEQDTEFGNTAHLGDCH++ +S++ ++ G +S Sbjct: 541 CGRVTPGMLAEGYEQDTEFGNTAHLGDCHEILPTSTTPDYKIFGGPTS 588 >gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens] Length = 998 Score = 1177 bits (3046), Expect = 0.0 Identities = 574/585 (98%), Positives = 576/585 (98%), Gaps = 2/585 (0%) Query: 1 MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQ 60 MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQ Sbjct: 1 MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQ 60 Query: 61 LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHN 120 LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHN Sbjct: 61 LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHN 120 Query: 121 FIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFAD 180 FIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFAD Sbjct: 121 FIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFAD 180 Query: 181 GKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREI 240 GKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREI Sbjct: 181 GKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREI 240 Query: 241 AVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSI 300 AVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSI Sbjct: 241 AVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSI 300 Query: 301 TDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPED 360 TDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPED Sbjct: 301 TDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPED 360 Query: 361 KVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYR 420 KVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYR Sbjct: 361 KVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYR 420 Query: 421 LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAE 480 LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAE Sbjct: 421 LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAE 480 Query: 481 NEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGS 540 NEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGS Sbjct: 481 NEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGS 540 Query: 541 CGRVTPGMLAEGYEQDTEFGNTAHLGDCHDM--EVSSSSVTTMVY 583 CGRVTPGMLAEGYEQDTEFGNTAHLGDCH + EV S MV+ Sbjct: 541 CGRVTPGMLAEGYEQDTEFGNTAHLGDCHGVRWEVQSGESNQMVH 585 >gi|24234729 semaphorin 6D isoform 1 precursor [Homo sapiens] Length = 1011 Score = 1168 bits (3022), Expect = 0.0 Identities = 574/598 (95%), Positives = 576/598 (96%), Gaps = 15/598 (2%) Query: 1 MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQ 60 MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQ Sbjct: 1 MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQ 60 Query: 61 LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHN 120 LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHN Sbjct: 61 LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHN 120 Query: 121 FIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFAD 180 FIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFAD Sbjct: 121 FIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFAD 180 Query: 181 GKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREI 240 GKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREI Sbjct: 181 GKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREI 240 Query: 241 AVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSI 300 AVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSI Sbjct: 241 AVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSI 300 Query: 301 TDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPED 360 TDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPED Sbjct: 301 TDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPED 360 Query: 361 KVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYR 420 KVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYR Sbjct: 361 KVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYR 420 Query: 421 LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAE 480 LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAE Sbjct: 421 LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAE 480 Query: 481 NEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGS 540 NEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGS Sbjct: 481 NEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGS 540 Query: 541 CGRVTPGML-------------AEGYEQDTEFGNTAHLGDCHDM--EVSSSSVTTMVY 583 CGRVTPGML AEGYEQDTEFGNTAHLGDCH + EV S MV+ Sbjct: 541 CGRVTPGMLLLTEDFFAFHNHSAEGYEQDTEFGNTAHLGDCHGVRWEVQSGESNQMVH 598 >gi|24234732 semaphorin 6D isoform 6 precursor [Homo sapiens] Length = 476 Score = 976 bits (2522), Expect = 0.0 Identities = 476/476 (100%), Positives = 476/476 (100%) Query: 1 MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQ 60 MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQ Sbjct: 1 MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQ 60 Query: 61 LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHN 120 LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHN Sbjct: 61 LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHN 120 Query: 121 FIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFAD 180 FIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFAD Sbjct: 121 FIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFAD 180 Query: 181 GKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREI 240 GKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREI Sbjct: 181 GKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREI 240 Query: 241 AVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSI 300 AVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSI Sbjct: 241 AVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSI 300 Query: 301 TDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPED 360 TDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPED Sbjct: 301 TDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPED 360 Query: 361 KVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYR 420 KVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYR Sbjct: 361 KVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYR 420 Query: 421 LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAK 476 LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAK Sbjct: 421 LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAK 476 >gi|11991660 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A [Homo sapiens] Length = 1030 Score = 738 bits (1906), Expect = 0.0 Identities = 348/589 (59%), Positives = 452/589 (76%), Gaps = 7/589 (1%) Query: 8 AYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRG-RPSGNESQ-HRLDFQLMLKI 65 A +L + FPED EP++ +Y++QYPVF G +P N +Q HRLD Q+++ + Sbjct: 5 ALLLYFTLLHFAGAGFPEDSEPISISHGNYTKQYPVFVGHKPGRNTTQRHRLDIQMIMIM 64 Query: 66 RDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHNFIKVF 125 TLYIA RD +YTV+++ E+ +KKLTW+SRQ D + C MKGKHKDECHNFIKV Sbjct: 65 NGTLYIAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKGKHKDECHNFIKVL 124 Query: 126 VPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFADGKLYS 185 + +ND+ +FVCGTNAFNP CR Y++ TLE G+E SG+ARCP+DA+ NVALFADGKLYS Sbjct: 125 LKKNDDALFVCGTNAFNPSCRNYKMDTLEPFGDEFSGMARCPYDAKHANVALFADGKLYS 184 Query: 186 ATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIAVEHN 245 ATV DFLA DAVIYRS+G+ LRT+K+DSKW+KEP+F+ A++YG+Y+YFFFREIAVE+N Sbjct: 185 ATVTDFLAIDAVIYRSLGESPTLRTVKHDSKWLKEPYFVQAVDYGDYIYFFFREIAVEYN 244 Query: 246 NLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDIIQ 305 +GK V+ RVA++CKNDMGGSQRVLEK WTSFLKARLNCSVPGDS FYF++LQ++TD+I+ Sbjct: 245 TMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNILQAVTDVIR 304 Query: 306 INGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKP 365 ING V+ F+T NSIPGSAVCA+ M DI VF GRFKEQK+PDS WT VP+++VPKP Sbjct: 305 INGRDVVLATFSTPYNSIPGSAVCAYDMLDIASVFTGRFKEQKSPDSTWTPVPDERVPKP 364 Query: 366 RPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAIS 425 RPGCCA E Y TS +FPD+TL+FIK+HPLMD AVP I + PWF +T VRYRLT I+ Sbjct: 365 RPGCCAGSSSLERYATSNEFPDDTLNFIKTHPLMDEAVPSIFNRPWFLRTMVRYRLTKIA 424 Query: 426 VDHSAGPYQNYTVIFVGSEAGMVLKVLAK--TSPFSLNDSVLLEEIEAYNHAKCSAENEE 483 VD +AGPYQN+TV+F+GSE G++LK LA+ S F LNDS+ LEE+ YN KCS + E Sbjct: 425 VDTAAGPYQNHTVVFLGSEKGIILKFLARIGNSGF-LNDSLFLEEMSVYNSEKCSYDGVE 483 Query: 484 DKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQ-GSCG 542 DK+++ +QLD+ +LYVAFS+C+I++PL RCER+G CKK+CIASRDPYCGW+ + G+C Sbjct: 484 DKRIMGMQLDRASSSLYVAFSTCVIKVPLGRCERHGKCKKTCIASRDPYCGWIKEGGACS 543 Query: 543 RVTPGMLAEGYEQDTEFGNTAHLGDCHDMEVSSSSVTTMVYDGKSSLES 591 ++P +EQD E GNT LGDCH+ V+ + ++ + ++ +S Sbjct: 544 HLSPNSRLT-FEQDIERGNTDGLGDCHNSFVALNGHSSSLLPSTTTSDS 591 >gi|19718780 semaphorin 6B precursor [Homo sapiens] Length = 888 Score = 608 bits (1567), Expect = e-174 Identities = 295/570 (51%), Positives = 392/570 (68%), Gaps = 12/570 (2%) Query: 8 AYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGN----ESQHRLDFQLML 63 A +LLL++ FPE+ PL+ Y YPVF G G E L+ Q +L Sbjct: 12 ALLLLLLLLGGAHGLFPEEPPPLSVAPRDYLNHYPVFVGSGPGRLTPAEGADDLNIQRVL 71 Query: 64 KIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHNFIK 123 ++ TL+I RD +Y V L TE+ +KLTWRS D C MKGK + EC NF+K Sbjct: 72 RVNRTLFIGDRDNLYRVELEPPTSTELRYQRKLTWRSNPSDINVCRMKGKQEGECRNFVK 131 Query: 124 VFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFADGKL 183 V + R++ +FVCG+NAFNP+C Y + TL+ G+ ISG+ARCP+D + NVALF+DG L Sbjct: 132 VLLLRDESTLFVCGSNAFNPVCANYSIDTLQPVGDNISGMARCPYDPKHANVALFSDGML 191 Query: 184 YSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIAVE 243 ++ATV DFLA DAVIYRS+GD LRT+K+DSKW KEP+F+HA+E+G++VYFFFREIA+E Sbjct: 192 FTATVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWFKEPYFVHAVEWGSHVYFFFREIAME 251 Query: 244 HNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDI 303 N L K V SRVAR+CKND+GGS RVLEK WTSFLKARLNCSVPGDS FYF+VLQ++T + Sbjct: 252 FNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSHFYFNVLQAVTGV 311 Query: 304 IQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVP 363 + + G P V+ VF+T NSIPGSAVCAF + + VF+GRF+EQK+P+S+WT VPED+VP Sbjct: 312 VSLGGRPVVLAVFSTPSNSIPGSAVCAFDLTQVAAVFEGRFREQKSPESIWTPVPEDQVP 371 Query: 364 KPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTA 423 +PRPGCCA G+ Y S PD+ L+F+K+HPLMD AVP + PW +T +R++LT Sbjct: 372 RPRPGCCAAPGM--QYNASSALPDDILNFVKTHPLMDEAVPSLGHAPWILRTLMRHQLTR 429 Query: 424 ISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLND---SVLLEEIEAYNHAKCS-- 478 ++VD AGP+ N TV+F+GSEAG VLK L + + + SV LEE E Y +C Sbjct: 430 VAVDVGAGPWGNQTVVFLGSEAGTVLKFLVRPNASTSGTSGLSVFLEEFETYRPDRCGRP 489 Query: 479 AENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQ 538 E ++++SL+LD L AF C++R+P++RC++Y C K+CI S+DPYCGW Sbjct: 490 GGGETGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQQYSGCMKNCIGSQDPYCGWAPD 549 Query: 539 GSCGRVTPGMLAEGYEQDTEFGNTAHLGDC 568 GSC ++PG A +EQD +T+ LGDC Sbjct: 550 GSCIFLSPGTRA-AFEQDVSGASTSGLGDC 578 >gi|16306552 semaphorin Y [Homo sapiens] Length = 930 Score = 586 bits (1510), Expect = e-167 Identities = 294/580 (50%), Positives = 398/580 (68%), Gaps = 13/580 (2%) Query: 4 FLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRG-RPSGNESQHRLDFQLM 62 F+ +LLL+ +FP+D PL D + FRG ++ LDFQ Sbjct: 7 FMPLLLLLLLLSLPHTQAAFPQDPLPLLISDLQGTSPLSWFRGLEDDAVAAELGLDFQRF 66 Query: 63 LKIRDTLYIAGRDQVYTVNLNEMPKTE-VIPNKKLTWRSRQQDRENCAMKGKHKDECHNF 121 L + TL +A RD V++ +L + E ++PNK LTWRS QD ENCA++GK DEC+N+ Sbjct: 67 LTLNRTLLVAARDHVFSFDLQAEEEGEGLVPNKYLTWRS--QDVENCAVRGKLTDECYNY 124 Query: 122 IKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFADG 181 I+V VP + + + CGTN+F+P+CR Y +++L+ +GEE+SG ARCPFDA Q+NVA+FA+G Sbjct: 125 IRVLVPWDSQTLLACGTNSFSPVCRSYGITSLQQEGEELSGQARCPFDATQSNVAIFAEG 184 Query: 182 KLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIA 241 LYSAT ADF ASDAV+YRS+G LR+ KYDSKW++EPHF+ A+E+G++VYFFFRE++ Sbjct: 185 SLYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVQALEHGDHVYFFFREVS 244 Query: 242 VEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSIT 301 VE LG+ +SRVAR+CK DMGGS R L++HWTSFLK RLNCSVPGDS FYFDVLQ++T Sbjct: 245 VEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTFYFDVLQALT 304 Query: 302 DIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDK 361 + ++G + GVFTTQ NSIPGSAVCAF +D+IE+ F+G+FKEQ++ D WT V ED+ Sbjct: 305 GPVNLHGRSALFGVFTTQTNSIPGSAVCAFYLDEIERGFEGKFKEQRSLDGAWTPVSEDR 364 Query: 362 VPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRL 421 VP PRPG CA G A + +S D PD+ L+FIK+HPL+D AVPP+ +P T T R L Sbjct: 365 VPSPRPGSCAGVGGAALFSSSRDLPDDVLTFIKAHPLLDPAVPPVTHQPLLTLTS-RALL 423 Query: 422 TAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAEN 481 T ++VD AGP+ N TV+F+GS G VLKVL + +LLEEI+AY+ A+CS + Sbjct: 424 TQVAVDGMAGPHSNITVMFLGSNDGTVLKVLTPGGRSGGPEPILLEEIDAYSPARCSGKR 483 Query: 482 --EEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQG 539 + +++I L+LD + H L+VAFS CI+ +PLSRC R+G+C++SC+AS+DPYCGW S Sbjct: 484 TAQTARRIIGLELDTEGHRLFVAFSGCIVYLPLSRCARHGACQRSCLASQDPYCGWHSSR 543 Query: 540 SCGRVTPGMLAEGYEQDTEFGNTAHL--GDCHDMEVSSSS 577 C + G + GN + GDC D S S Sbjct: 544 GCVDIR----GSGGTDVDQAGNQESMEHGDCQDGATGSQS 579 >gi|41406086 semaphorin 3D [Homo sapiens] Length = 777 Score = 315 bits (806), Expect = 1e-85 Identities = 191/550 (34%), Positives = 286/550 (52%), Gaps = 41/550 (7%) Query: 53 SQHRLDFQLML--KIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAM 110 S LDFQ +L + R L + +D ++ ++L ++ K KK+ W + ++ E C + Sbjct: 64 SSEGLDFQTLLLDEERGRLLLGAKDHIFLLSLVDLNKNF----KKIYWPAAKERVELCKL 119 Query: 111 KGKHKD-ECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYD-------GEEISG 162 GK + EC NFI+V P N ++VCGT AF+P+C Y L + D SG Sbjct: 120 AGKDANTECANFIRVLQPYNKTHIYVCGTGAFHPICGYIDLGVYKEDIIFKLDTHNLESG 179 Query: 163 LARCPFDARQTNVALFADGKLYSATVADFLASDAVIYRSMG---DGSALRTIKYDSKWIK 219 +CPFD +Q ++ D LYS T +DFL D RS+G D +RT + W+ Sbjct: 180 RLKCPFDPQQPFASVMTDEYLYSGTASDFLGKDTAFTRSLGPTHDHHYIRTDISEHYWLN 239 Query: 220 EPHFLHAIEY-------GNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEK 272 F+ + +YFFFRE + E + K + SRV R+CKND+GG + ++ K Sbjct: 240 GAKFIGTFFIPDTYNPDDDKIYFFFRESSQEGSTSDKTILSRVGRVCKNDVGGQRSLINK 299 Query: 273 HWTSFLKARLNCSVPGD--SFFYFDVLQSITDI-IQINGIPTVVGVFTTQLNSIPGSAVC 329 WT+FLKARL CS+PG + YFD LQ I + + P V GVFTT + GSAVC Sbjct: 300 -WTTFLKARLICSIPGSDGADTYFDELQDIYLLPTRDERNPVVYGVFTTTSSIFKGSAVC 358 Query: 330 AFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDET 389 +SM DI VF G + +++ D W + ++P PRPG C K++ DFPD+ Sbjct: 359 VYSMADIRAVFNGPYAHKESADHRWVQY-DGRIPYPRPGTCPSKTYDPLIKSTRDFPDDV 417 Query: 390 LSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVL 449 +SFIK H +M +V P+A P F + V YRLT I VDH Y V+F+G++ G VL Sbjct: 418 ISFIKRHSVMYKSVYPVAGGPTFKRINVDYRLTQIVVDHVIAEDGQYDVMFLGTDIGTVL 477 Query: 450 KVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIR 509 KV++ + + V+LEE++ + H+ +++++L LY+ +++ Sbjct: 478 KVVSISKEKWNMEEVVLEELQIFKHSSI---------ILNMELSLKQQQLYIGSRDGLVQ 528 Query: 510 IPLSRCERYGSCKKSCIASRDPYCGWLSQGSCGRVTPGMLAEGYEQDTEFGNTAHLGDCH 569 + L RC+ YG C +RDPYC W +C R P QD ++G+ + C Sbjct: 529 LSLHRCDTYGKACADCCLARDPYCAW-DGNACSRYAPTSKRRARRQDVKYGDP--ITQCW 585 Query: 570 DMEVSSSSVT 579 D+E S S T Sbjct: 586 DIEDSISHET 595 >gi|91982767 semaphorin 5B isoform 1 [Homo sapiens] Length = 1151 Score = 308 bits (790), Expect = 7e-84 Identities = 191/525 (36%), Positives = 297/525 (56%), Gaps = 47/525 (8%) Query: 12 LLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQLMLKIRDTLYI 71 L +S+ V+F + ++ Y +R + PSGN QL++ R+ L+ Sbjct: 97 LCALSKHPTVAFEDLQPWVSNFTYPGARDFSQLALDPSGN--------QLIVGARNYLF- 147 Query: 72 AGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHNFIKVFVPRNDE 131 ++ N++ + TE W S + R +C KGK ++EC N+++V + + Sbjct: 148 ----RLSLANVSLLQATE--------WASSEDTRRSCQSKGKTEEECQNYVRVLIVAGRK 195 Query: 132 MVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFAD-GKLYSATVAD 190 VF+CGTNAF+PMC ++ L E+I+G+ARCP+D R + A+ + G+LY+ATV D Sbjct: 196 -VFMCGTNAFSPMCTSRQVGNLSRTIEKINGVARCPYDPRHNSTAVISSQGELYAATVID 254 Query: 191 FLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIAVEHNNLGKA 250 F D IYRS+G G LRT +Y+SKW+ EP+F+ A + G + YFF RE AVEH + G+ Sbjct: 255 FSGRDPAIYRSLGSGPPLRTAQYNSKWLNEPNFVAAYDIGLFAYFFLRENAVEH-DCGRT 313 Query: 251 VYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDIIQINGIP 310 VYSRVAR+CKND+GG + +LE WT+F+KARLNCS PG+ FY++ LQS + + + Sbjct: 314 VYSRVARVCKNDVGG-RFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSAFHLPEQD--- 369 Query: 311 TVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCC 370 + GVFTT +NSI SAVCAF++ I + F G F+ Q+ P + W + + +P + G Sbjct: 370 LIYGVFTTNVNSIAASAVCAFNLSAISQAFNGPFRYQENPRAAWLPI-ANPIPNFQCGTL 428 Query: 371 AKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAISVDHSA 430 + G E + + +L + LM AV P+ EP T+ VR+ + + VD Sbjct: 429 PETGPNE------NLTERSLQDAQRLFLMSEAVQPVTPEPCVTQDSVRF--SHLVVDLVQ 480 Query: 431 GPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISL 490 Y V+++G+E+G +LK L+ T+ SL+ LEE+ + + + SL Sbjct: 481 AKDTLYHVLYIGTESGTILKALS-TASRSLH-GCYLEELHVLPPGR-------REPLRSL 531 Query: 491 QLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGW 535 ++ AL+V ++R+PL RC Y S + +C+ +RDPYCGW Sbjct: 532 RILHSARALFVGLRDGVLRVPLERCAAYRS-QGACLGARDPYCGW 575 >gi|5174673 semaphorin 3A precursor [Homo sapiens] Length = 771 Score = 303 bits (776), Expect = 3e-82 Identities = 184/529 (34%), Positives = 276/529 (52%), Gaps = 48/529 (9%) Query: 66 RDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKH-KDECHNFIKV 124 R LY+ +D +++ +L + +K+ W R+ C GK EC NFIKV Sbjct: 66 RSRLYVGAKDHIFSFDL-----VNIKDFQKIVWPVSYTRRDECKWAGKDILKECANFIKV 120 Query: 125 FVPRNDEMVFVCGTNAFNPMCRYYRLS--------TLEYDGEEISGLARCPFDARQTNVA 176 N ++ CGT AF+P+C Y + LE E +G + P+D + + Sbjct: 121 LKAYNQTHLYACGTGAFHPICTYIEIGHHPEDNIFKLENSHFE-NGRGKSPYDPKLLTAS 179 Query: 177 LFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFL--HAIEYG---- 230 L DG+LYS T ADF+ D I+R++G +RT ++DS+W+ +P F+ H I Sbjct: 180 LLIDGELYSGTAADFMGRDFAIFRTLGHHHPIRTEQHDSRWLNDPKFISAHLISESDNPE 239 Query: 231 -NYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGD 289 + VYFFFRE A++ + GKA ++R+ +ICKND GG + ++ K WT+FLKARL CSVPG Sbjct: 240 DDKVYFFFRENAIDGEHSGKATHARIGQICKNDFGGHRSLVNK-WTTFLKARLICSVPGP 298 Query: 290 SFF--YFDVLQSITDIIQIN----GIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGR 343 + +FD LQ D+ +N P V GVFTT N GSAVC +SM D+ +VF G Sbjct: 299 NGIDTHFDELQ---DVFLMNFKDPKNPVVYGVFTTSSNIFKGSAVCMYSMSDVRRVFLGP 355 Query: 344 FKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAV 403 + + P+ W + +VP PRPG C + ++ D PD+ ++F +SHP M + V Sbjct: 356 YAHRDGPNYQWVPY-QGRVPYPRPGTCPSKTFG-GFDSTKDLPDDVITFARSHPAMYNPV 413 Query: 404 PPIADEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLA--KTSPFSLN 461 P+ + P KT V Y+ T I VD Y V+F+G++ G VLKV++ K + + L Sbjct: 414 FPMNNRPIVIKTDVNYQFTQIVVDRVDAEDGQYDVMFIGTDVGTVLKVVSIPKETWYDL- 472 Query: 462 DSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSC 521 + VLLEE+ + E + +++L LY+ ++ + ++PL RC+ YG Sbjct: 473 EEVLLEEMTVF---------REPTAISAMELSTKQQQLYIGSTAGVAQLPLHRCDIYGKA 523 Query: 522 KKSCIASRDPYCGWLSQGSCGRVTPGMLAEGYEQDTEFGN-TAHLGDCH 569 C +RDPYC W +C R P QD G+ H D H Sbjct: 524 CAECCLARDPYCAW-DGSACSRYFPTAKRRTRRQDIRNGDPLTHCSDLH 571 >gi|6912650 semaphorin 3E [Homo sapiens] Length = 775 Score = 298 bits (764), Expect = 7e-81 Identities = 184/531 (34%), Positives = 275/531 (51%), Gaps = 41/531 (7%) Query: 57 LDFQLML--KIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKH 114 LD ML + ++ L++ GRD VY+++L + K++ W S E C MKGK Sbjct: 56 LDLHTMLLDEYQERLFVGGRDLVYSLSLERISDGY----KEIHWPSTALKMEECIMKGKD 111 Query: 115 KDECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYR--------LSTLEYDGEEISGLARC 166 EC N+++V N + CGT AF+P+C + R L LE E G RC Sbjct: 112 AGECANYVRVLHHYNRTHLLTCGTGAFDPVCAFIRVGYHLEDPLFHLESPRSE-RGRGRC 170 Query: 167 PFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHA 226 PFD + ++ +L++ +D+ + DA I+RSMG + +RT D + +KEP F+ + Sbjct: 171 PFDPSSSFISTLIGSELFAGLYSDYWSRDAAIFRSMGRLAHIRTEHDDERLLKEPKFVGS 230 Query: 227 IEY-------GNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLK 279 N VYFFF E A+E N A+Y+RV R+C ND+GG QR+L W++FLK Sbjct: 231 YMIPDNEDRDDNKVYFFFTEKALEAENNAHAIYTRVGRLCVNDVGG-QRILVNKWSTFLK 289 Query: 280 ARLNCSVPGDSFF--YFDVLQSITDI-IQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDI 336 ARL CSVPG + YFD L+ + + + + P + G+F T N G A+C + M I Sbjct: 290 ARLVCSVPGMNGIDTYFDELEDVFLLPTRDHKNPVIFGLFNTTSNIFRGHAICVYHMSSI 349 Query: 337 EKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSH 396 F G + ++ P+ W+ V E KVP PRPG CA Y T+ D+PD+ + F +SH Sbjct: 350 RAAFNGPYAHKEGPEYHWS-VYEGKVPYPRPGSCASKVNGGRYGTTKDYPDDAIRFARSH 408 Query: 397 PLMDSAVPPIADEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLA-KT 455 PLM A+ P +P KT +Y L I+VD Y V+F+G++ G+VLKV+ Sbjct: 409 PLMYQAIKPAHKKPILVKTDGKYNLKQIAVDRVEAEDGQYDVLFIGTDNGIVLKVITIYN 468 Query: 456 SPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRC 515 + V+LEE++ + ++ +IS+++ LY+ +S + ++ C Sbjct: 469 QEMESMEEVILEELQIF---------KDPVPIISMEISSKRQQLYIGSASAVAQVRFHHC 519 Query: 516 ERYGSCKKSCIASRDPYCGWLSQGSCGRVTP-GMLAEG--YEQDTEFGNTA 563 + YGS C +RDPYC W SC R P G A+ QD GN A Sbjct: 520 DMYGSACADCCLARDPYCAW-DGISCSRYYPTGTHAKRRFRRQDVRHGNAA 569 >gi|147904700 semaphorin 5A [Homo sapiens] Length = 1074 Score = 295 bits (755), Expect = 8e-80 Identities = 172/469 (36%), Positives = 260/469 (55%), Gaps = 34/469 (7%) Query: 69 LYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHNFIKVFVPR 128 L + R+ ++ + L ++ + + W + ++ C KGK K+EC N+I+V + Sbjct: 70 LVVGARNYLFRLQLEDLSLIQAVE-----WECDEATKKACYSKGKSKEECQNYIRVLLVG 124 Query: 129 NDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALF-ADGKLYSAT 187 D + F CGTNAF P+C LS L ++ISG+ARCP+ + + AL A G+LY+AT Sbjct: 125 GDRL-FTCGTNAFTPVCTNRSLSNLTEIHDQISGMARCPYSPQHNSTALLTAGGELYAAT 183 Query: 188 VADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIAVEHNNL 247 DF D IYRS+G LRT +Y+SKW+ EP+F+ + + GN+ YFFFRE AVEH + Sbjct: 184 AMDFPGRDPAIYRSLGILPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVEH-DC 242 Query: 248 GKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDIIQIN 307 GK V+SR AR+CKND+GG + +LE WT+F+KARLNCS PG+ FY++ LQS + +++ Sbjct: 243 GKTVFSRAARVCKNDIGG-RFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSTFFLPELD 301 Query: 308 GIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRP 367 + G+FTT +NSI SAVC F++ I + F G FK Q+ S W P P P Sbjct: 302 ---LIYGIFTTNVNSIAASAVCVFNLSAIAQAFSGPFKYQENSRSAWLPYPN---PNPHF 355 Query: 368 GC-CAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAISV 426 C GL ++ + L + LM V P+ P F + R+ + ++V Sbjct: 356 QCGTVDQGL------YVNLTERNLQDAQKFILMHEVVQPVTTVPSFMEDNSRF--SHVAV 407 Query: 427 DHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKK 486 D G +I++ ++ G + KV + S S LLEEIE + + Sbjct: 408 DVVQGREALVHIIYLATDYGTIKKVRVPLNQTS--SSCLLEEIELF-------PERRREP 458 Query: 487 VISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGW 535 + SLQ+ L+V +++IPL RC+ Y + + +CI ++DPYCGW Sbjct: 459 IRSLQILHSQSVLFVGLREHVVKIPLKRCQFYRT-RSTCIGAQDPYCGW 506 >gi|188497703 semaphorin 3F [Homo sapiens] Length = 785 Score = 294 bits (752), Expect = 2e-79 Identities = 180/557 (32%), Positives = 282/557 (50%), Gaps = 72/557 (12%) Query: 58 DFQLMLKIRD--TLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHK 115 D++++LK D +Y+ +D V +++L+++ + +I + W + Q E C + GK Sbjct: 56 DYRILLKDEDHDRMYVGSKDYVLSLDLHDINREPLI----IHWAASPQRIEECVLSGKDV 111 Query: 116 D-ECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYR------------------------- 149 + EC NF+++ P N ++VCGT A+NPMC Y Sbjct: 112 NGECGNFVRLIQPWNRTHLYVCGTGAYNPMCTYVNRGRRAQATPWTQTQAVRGRGSRATD 171 Query: 150 --------------LSTLEYDGEEISGLARCPFDARQTNVALFADGKLYSATVADFLASD 195 + LE + E SG +CP+D + + + +LY+ DF+ +D Sbjct: 172 GALRPMPTAPRQDYIFYLEPERLE-SGKGKCPYDPKLDTASALINEELYAGVYIDFMGTD 230 Query: 196 AVIYRSMGDGSALRTIKYDSKWIKEPHFLHAI-------EYGNYVYFFFREIAVEHNNLG 248 A I+R++G +A+RT +Y+S+W+ +P F+HA + +YFFFRE + E Sbjct: 231 AAIFRTLGKQTAMRTDQYNSRWLNDPSFIHAELIPDSAERNDDKLYFFFRERSAEAPQ-S 289 Query: 249 KAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFF--YFDVLQSITDIIQI 306 AVY+R+ RIC ND GG ++ K W++FLKARL CSVPG+ +FD LQ + + Q Sbjct: 290 PAVYARIGRICLNDDGGHCCLVNK-WSTFLKARLVCSVPGEDGIETHFDELQDVF-VQQT 347 Query: 307 NGI--PTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPK 364 + P + VFT+ + GSAVC +SM DI VF G F ++ P+ W K+P Sbjct: 348 QDVRNPVIYAVFTSSGSVFRGSAVCVYSMADIRMVFNGPFAHKEGPNYQWMPF-SGKMPY 406 Query: 365 PRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAI 424 PRPG C + K++ D+PDE ++F++SHPLM AV P+ P +T YRLT I Sbjct: 407 PRPGTCPGGTFTPSMKSTKDYPDEVINFMRSHPLMYQAVYPLQRRPLVVRTGAPYRLTTI 466 Query: 425 SVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEED 484 +VD Y V+F+G++ G V KV+ + ++LEE+E + ++ Sbjct: 467 AVDQVDAADGRYEVLFLGTDRGTVQKVIVLPKDDQELEELMLEEVEVF---------KDP 517 Query: 485 KKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGSCGRV 544 V ++ + LYVA + + + L RC+ YG+ C +RDPYC W Q +C R Sbjct: 518 APVKTMTISSKRQQLYVASAVGVTHLSLHRCQAYGAACADCCLARDPYCAWDGQ-ACSRY 576 Query: 545 TPGMLAEGYEQDTEFGN 561 T QD GN Sbjct: 577 TASSKRRSRRQDVRHGN 593 >gi|5454048 semaphorin 3C [Homo sapiens] Length = 751 Score = 288 bits (738), Expect = 8e-78 Identities = 171/529 (32%), Positives = 280/529 (52%), Gaps = 37/529 (6%) Query: 53 SQHRLDFQLML--KIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAM 110 S H LD++++L + +D +Y+ +D + ++N+N + + + + W + E C M Sbjct: 48 SHHPLDYRILLMDEDQDRIYVGSKDHILSLNINNISQEAL----SVFWPASTIKVEECKM 103 Query: 111 KGKHKDE-CHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLS------TLEYDGEEISGL 163 GK C NF++V N ++VCG+ AF+P+C Y D + SG Sbjct: 104 AGKDPTHGCGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGK 163 Query: 164 ARCPFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHF 223 RC F+ V++ + +L+S DF+ +DA I+RS+ +A+RT +++SKW+ EP F Sbjct: 164 GRCSFNPNVNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMF 223 Query: 224 L--HAIEYGN-----YVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTS 276 + H I G VYFFF+E ++N K ++S +ARIC ND GG + ++ K WT+ Sbjct: 224 VDAHVIPDGTDPNDAKVYFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSLVNK-WTT 282 Query: 277 FLKARLNCSVPGDSF--FYFDVLQSITDIIQINGIPTVV-GVFTTQLNSIPGSAVCAFSM 333 FLKARL CSV + +FD L+ + + N T+V G+FTT + GSAVC + + Sbjct: 283 FLKARLVCSVTDEDGPETHFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHL 342 Query: 334 DDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFI 393 DI+ VF G F ++ P+ + + ++P PRPG C +T+ +FPD+ ++FI Sbjct: 343 SDIQTVFNGPFAHKEGPNHQLISY-QGRIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFI 401 Query: 394 KSHPLMDSAVPPIADEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLA 453 ++HPLM +++ PI P + Y+ T I+VD Y V+F+G++ G V KV+ Sbjct: 402 RNHPLMYNSIYPIHKRPLIVRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVV 461 Query: 454 KTSPFSLNDSVLLEEIEAY-NHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPL 512 + S++ ++LEE+E + NHA + ++++ LYV+ + + ++ L Sbjct: 462 LPTNNSVSGELILEELEVFKNHA----------PITTMKISSKKQQLYVSSNEGVSQVSL 511 Query: 513 SRCERYGSCKKSCIASRDPYCGWLSQGSCGRVTPGMLAEGYEQDTEFGN 561 RC YG+ C +RDPYC W SC R P QD GN Sbjct: 512 HRCHIYGTACADCCLARDPYCAW-DGHSCSRFYPTGKRRSRRQDVRHGN 559 >gi|4759092 semaphorin 3B isoform 1 precursor [Homo sapiens] Length = 749 Score = 287 bits (734), Expect = 2e-77 Identities = 181/520 (34%), Positives = 266/520 (51%), Gaps = 38/520 (7%) Query: 66 RDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKH-KDECHNFIKV 124 R L++ + V ++NL+ + K KKL W + + RE C GK EC NF+K+ Sbjct: 64 RGRLFVGAENHVASLNLDNISKRA----KKLAWPAPVEWREECNWAGKDIGTECMNFVKL 119 Query: 125 FVPRNDEMVFVCGTNAFNPMCRYYRLS------TLEYDGEEIS-GLARCPFDARQTNVAL 177 N + CGT AF+P C + + L D I G + P+D R ++ Sbjct: 120 LHAYNRTHLLACGTGAFHPTCAFVEVGHRAEEPVLRLDPGRIEDGKGKSPYDPRHRAASV 179 Query: 178 FADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEY-------G 230 +LYS AD + D I+RS+G +LRT +DS+W+ EP F+ Sbjct: 180 LVGEELYSGVAADLMGRDFTIFRSLGQRPSLRTEPHDSRWLNEPKFVKVFWIPESENPDD 239 Query: 231 NYVYFFFREIAVEHNN-LGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPG- 288 + +YFFFRE AVE LG+ SRV +IC+ND+GG QR L WT+FLKARL CSVPG Sbjct: 240 DKIYFFFRETAVEAAPALGRLSVSRVGQICRNDVGG-QRSLVNKWTTFLKARLVCSVPGV 298 Query: 289 DSFFYFDVLQSITDII-QINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQ 347 + +FD LQ + + + + P + VF+T + GSAVC +SM+D+ + F G F + Sbjct: 299 EGDTHFDQLQDVFLLSSRDHRTPLLYAVFSTSSSIFQGSAVCVYSMNDVRRAFLGPFAHK 358 Query: 348 KTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIA 407 + P W + + +VP PRPG C + ++ DFPD+ + F ++HPLM ++V P Sbjct: 359 EGPMHQWVSY-QGRVPYPRPGMCPSKTFG-TFSSTKDFPDDVIQFARNHPLMYNSVLPTG 416 Query: 408 DEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLA--KTSPFSLNDSVL 465 P F + Y T I+ D A +Y V+F+G++ G VLKV++ K S S + +L Sbjct: 417 GRPLFLQVGANYTFTQIAADRVAAADGHYDVLFIGTDVGTVLKVISVPKGSRPSA-EGLL 475 Query: 466 LEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSC 525 LEE+ + E+ V S+Q+ H LYVA S + +I L RC +G C Sbjct: 476 LEELHVF---------EDSAAVTSMQISSKRHQLYVASRSAVAQIALHRCAAHGRVCTEC 526 Query: 526 IASRDPYCGWLSQGSCGRVTPGMLAEGYEQDTEFGNTAHL 565 +RDPYC W +C R P QD G+ + L Sbjct: 527 CLARDPYCAW-DGVACTRFQPSAKRRFRRQDVRNGDPSTL 565 >gi|54607089 semaphorin 3B isoform 2 precursor [Homo sapiens] Length = 748 Score = 283 bits (724), Expect = 3e-76 Identities = 181/520 (34%), Positives = 266/520 (51%), Gaps = 39/520 (7%) Query: 66 RDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKH-KDECHNFIKV 124 R L++ + V ++NL+ + K KKL W + + RE C GK EC NF+K+ Sbjct: 64 RGRLFVGAENHVASLNLDNISKRA----KKLAWPAPVEWREECNWAGKDIGTECMNFVKL 119 Query: 125 FVPRNDEMVFVCGTNAFNPMCRYYRLS------TLEYDGEEIS-GLARCPFDARQTNVAL 177 N + CGT AF+P C + + L D I G + P+D R ++ Sbjct: 120 LHAYNRTHLLACGTGAFHPTCAFVEVGHRAEEPVLRLDPGRIEDGKGKSPYDPRHRAASV 179 Query: 178 FADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEY-------G 230 +LYS AD + D I+RS+G +LRT +DS+W+ EP F+ Sbjct: 180 LVGEELYSGVAADLMGRDFTIFRSLGQRPSLRTEPHDSRWLNEPKFVKVFWIPESENPDD 239 Query: 231 NYVYFFFREIAVEHNN-LGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPG- 288 + +YFFFRE AVE LG+ SRV +IC+ND+GG QR L WT+FLKARL CSVPG Sbjct: 240 DKIYFFFRETAVEAAPALGRLSVSRVGQICRNDVGG-QRSLVNKWTTFLKARLVCSVPGV 298 Query: 289 DSFFYFDVLQSITDII-QINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQ 347 + +FD LQ + + + + P + VF+T + GSAVC +SM+D+ + F G F + Sbjct: 299 EGDTHFDQLQDVFLLSSRDHRTPLLYAVFSTS-SIFQGSAVCVYSMNDVRRAFLGPFAHK 357 Query: 348 KTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIA 407 + P W + + +VP PRPG C + ++ DFPD+ + F ++HPLM ++V P Sbjct: 358 EGPMHQWVSY-QGRVPYPRPGMCPSKTFG-TFSSTKDFPDDVIQFARNHPLMYNSVLPTG 415 Query: 408 DEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLA--KTSPFSLNDSVL 465 P F + Y T I+ D A +Y V+F+G++ G VLKV++ K S S + +L Sbjct: 416 GRPLFLQVGANYTFTQIAADRVAAADGHYDVLFIGTDVGTVLKVISVPKGSRPSA-EGLL 474 Query: 466 LEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSC 525 LEE+ + E+ V S+Q+ H LYVA S + +I L RC +G C Sbjct: 475 LEELHVF---------EDSAAVTSMQISSKRHQLYVASRSAVAQIALHRCAAHGRVCTEC 525 Query: 526 IASRDPYCGWLSQGSCGRVTPGMLAEGYEQDTEFGNTAHL 565 +RDPYC W +C R P QD G+ + L Sbjct: 526 CLARDPYCAW-DGVACTRFQPSAKRRFRRQDVRNGDPSTL 564 >gi|214010220 semaphorin 4D isoform 2 [Homo sapiens] Length = 738 Score = 281 bits (718), Expect = 2e-75 Identities = 177/494 (35%), Positives = 275/494 (55%), Gaps = 44/494 (8%) Query: 61 LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKD-ECH 119 L+ + +DTLYI R+ V+ VN + + + ++ W+ + + CA KGK K EC Sbjct: 54 LLSEDKDTLYIGAREAVFAVNALNISEKQ----HEVYWKVSEDKKAKCAEKGKSKQTECL 109 Query: 120 NFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFA 179 N+I+V P + ++VCGTNAF P C + L++ ++ G+ G RCPFD + ++ Sbjct: 110 NYIRVLQPLSATSLYVCGTNAFQPACDHLNLTSFKFLGKNEDGKGRCPFDPAHSYTSVMV 169 Query: 180 DGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEY---------- 229 DG+LYS T +FL S+ +I R+ S LRT +Y W+ EP F+ A Sbjct: 170 DGELYSGTSYNFLGSEPIISRN-SSHSPLRT-EYAIPWLNEPSFVFADVIRKSPDSPDGE 227 Query: 230 GNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGD 289 + VYFFF E++VE+ + + + R+AR+CK D GG R L+K WTSFLKARL CS P D Sbjct: 228 DDRVYFFFTEVSVEYEFVFRVLIPRIARVCKGDQGG-LRTLQKKWTSFLKARLICSRP-D 285 Query: 290 SFFYFDVLQSITDIIQING--IPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFK-GRFKE 346 S F+VL+ + +++ G +P +FT QLN++ SAVCA+++ E+VF G++ + Sbjct: 286 SGLVFNVLRDVF-VLRSPGLKVPVFYALFTPQLNNVGLSAVCAYNLSTAEEVFSHGKYMQ 344 Query: 347 QKTPDSVWT--AVPEDKVPKPRPGCCA-KHGLAEAYKTSIDFPDETLSFIKSHPLMDSAV 403 T + T VPKPRPG C A Y +S++ PD+TL F+K HPLMD +V Sbjct: 345 STTVEQSHTKWVRYNGPVPKPRPGACIDSEARAANYTSSLNLPDKTLQFVKDHPLMDDSV 404 Query: 404 PPIADEPWFTKTRVRYRLTAISVDHS-AGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLND 462 PI + P K V Y T I VD + A Y V+FV ++ G + K + SL Sbjct: 405 TPIDNRPRLIKKDVNY--TQIVVDRTQALDGTVYDVMFVSTDRGALHKAI------SLEH 456 Query: 463 SV-LLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSC 521 +V ++EE + + ++ E + + L K + +Y +S +++ PL+ C ++G+C Sbjct: 457 AVHIIEETQLF-------QDFEPVQTLLLSSKKGNRFVYAGSNSGVVQAPLAFCGKHGTC 509 Query: 522 KKSCIASRDPYCGW 535 + C+ +RDPYC W Sbjct: 510 -EDCVLARDPYCAW 522 >gi|214010218 semaphorin 4D isoform 1 [Homo sapiens] Length = 862 Score = 281 bits (718), Expect = 2e-75 Identities = 177/494 (35%), Positives = 275/494 (55%), Gaps = 44/494 (8%) Query: 61 LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKD-ECH 119 L+ + +DTLYI R+ V+ VN + + + ++ W+ + + CA KGK K EC Sbjct: 54 LLSEDKDTLYIGAREAVFAVNALNISEKQ----HEVYWKVSEDKKAKCAEKGKSKQTECL 109 Query: 120 NFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFA 179 N+I+V P + ++VCGTNAF P C + L++ ++ G+ G RCPFD + ++ Sbjct: 110 NYIRVLQPLSATSLYVCGTNAFQPACDHLNLTSFKFLGKNEDGKGRCPFDPAHSYTSVMV 169 Query: 180 DGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEY---------- 229 DG+LYS T +FL S+ +I R+ S LRT +Y W+ EP F+ A Sbjct: 170 DGELYSGTSYNFLGSEPIISRN-SSHSPLRT-EYAIPWLNEPSFVFADVIRKSPDSPDGE 227 Query: 230 GNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGD 289 + VYFFF E++VE+ + + + R+AR+CK D GG R L+K WTSFLKARL CS P D Sbjct: 228 DDRVYFFFTEVSVEYEFVFRVLIPRIARVCKGDQGG-LRTLQKKWTSFLKARLICSRP-D 285 Query: 290 SFFYFDVLQSITDIIQING--IPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFK-GRFKE 346 S F+VL+ + +++ G +P +FT QLN++ SAVCA+++ E+VF G++ + Sbjct: 286 SGLVFNVLRDVF-VLRSPGLKVPVFYALFTPQLNNVGLSAVCAYNLSTAEEVFSHGKYMQ 344 Query: 347 QKTPDSVWT--AVPEDKVPKPRPGCCA-KHGLAEAYKTSIDFPDETLSFIKSHPLMDSAV 403 T + T VPKPRPG C A Y +S++ PD+TL F+K HPLMD +V Sbjct: 345 STTVEQSHTKWVRYNGPVPKPRPGACIDSEARAANYTSSLNLPDKTLQFVKDHPLMDDSV 404 Query: 404 PPIADEPWFTKTRVRYRLTAISVDHS-AGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLND 462 PI + P K V Y T I VD + A Y V+FV ++ G + K + SL Sbjct: 405 TPIDNRPRLIKKDVNY--TQIVVDRTQALDGTVYDVMFVSTDRGALHKAI------SLEH 456 Query: 463 SV-LLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSC 521 +V ++EE + + ++ E + + L K + +Y +S +++ PL+ C ++G+C Sbjct: 457 AVHIIEETQLF-------QDFEPVQTLLLSSKKGNRFVYAGSNSGVVQAPLAFCGKHGTC 509 Query: 522 KKSCIASRDPYCGW 535 + C+ +RDPYC W Sbjct: 510 -EDCVLARDPYCAW 522 >gi|157388902 semaphorin 4C [Homo sapiens] Length = 833 Score = 268 bits (685), Expect = 1e-71 Identities = 166/487 (34%), Positives = 259/487 (53%), Gaps = 52/487 (10%) Query: 69 LYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKD-ECHNFIKVFVP 127 LY+ R+ ++ ++ + I +W + + + C KGK+ EC NFI+ P Sbjct: 65 LYVGAREALFAFSMEALELQGAI-----SWEAPVEKKTECIQKGKNNQTECFNFIRFLQP 119 Query: 128 RNDEMVFVCGTNAFNPMCRYYRLSTLEYD-GEEISGLARCPFDARQTNVALFADGKLYSA 186 N ++VCGT AF P C Y + T + GE G +CP+D + + L DG+LYSA Sbjct: 120 YNASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSA 179 Query: 187 TVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAI----EYGNY------VYFF 236 T+ +FL ++ +I R+MG +++T +Y + W+ EPHF+ + G++ VYFF Sbjct: 180 TLNNFLGTEPIILRNMGPHHSMKT-EYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFF 238 Query: 237 FREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDV 296 FRE AVE + + V +RVAR+CK DMGG+ R L++ WT+FLKARL CS P YF+ Sbjct: 239 FRERAVESDCYAEQVVARVARVCKGDMGGA-RTLQRKWTTFLKARLACSAPNWQ-LYFNQ 296 Query: 297 LQSITDIIQIN-GIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWT 355 LQ++ + + T GVF Q + SA+C + +++I++VF+G +KE W Sbjct: 297 LQAMHTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWD 356 Query: 356 AVPEDKVPKPRPGCC-----AKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEP 410 D VP PRPG C +HG Y +S++ PD L+F+K HPLM+ V P P Sbjct: 357 RY-TDPVPSPRPGSCINNWHRRHG----YTSSLELPDNILNFVKKHPLMEEQVGPRWSRP 411 Query: 411 WFTKTRVRYRLTAISVDHSAG-PYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSV-LLEE 468 K + T + D G YTV+F+G+ G +LK + SL V L+EE Sbjct: 412 LLVKKGTNF--THLVADRVTGLDGATYTVLFIGTGDGWLLKAV------SLGPWVHLIEE 463 Query: 469 IEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIAS 528 ++ + + + + SL L + L+ S ++++P++ C +Y SC C+ + Sbjct: 464 LQLF----------DQEPMRSLVLSQSKKLLFAGSRSQLVQLPVADCMKYRSC-ADCVLA 512 Query: 529 RDPYCGW 535 RDPYC W Sbjct: 513 RDPYCAW 519 >gi|39777610 semaphorin 4B precursor [Homo sapiens] Length = 837 Score = 261 bits (666), Expect = 2e-69 Identities = 186/565 (32%), Positives = 284/565 (50%), Gaps = 72/565 (12%) Query: 52 ESQHRLDFQLMLKIRD--TLYIAGRDQVYTV--NLNEMPKTEVIPNKKLTWRSRQQDREN 107 E++H ++ +L RD TLY+ R+ ++ + NL+ +P E ++L W + + ++ Sbjct: 63 EAEHISNYTALLLSRDGRTLYVGAREALFALSSNLSFLPGGEY---QELLWGADAEKKQQ 119 Query: 108 CAMKGKHKD-ECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEIS----- 161 C+ KGK +C N+IK+ +P + +F CGT AF+PMC Y + +E Sbjct: 120 CSFKGKDPQRDCQNYIKILLPLSGSHLFTCGTAAFSPMCTYINMENFTLARDEKGNVLLE 179 Query: 162 -GLARCPFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSK--WI 218 G RCPFD + AL DG+LY+ TV+ F +D I RS +LR K +S W+ Sbjct: 180 DGKGRCPFDPNFKSTALVVDGELYTGTVSSFQGNDPAISRSQ----SLRPTKTESSLNWL 235 Query: 219 KEPHFLHAIEY----------GNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQR 268 ++P F+ + + +YFFF E E + SR+ARICK D GG +R Sbjct: 236 QDPAFVASAYIPESLGSLQGDDDKIYFFFSETGQEFEFFENTIVSRIARICKGDEGG-ER 294 Query: 269 VLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDIIQINGIPT------VVGVFTTQLN- 321 VL++ WTSFLKA+L CS P D F F+VLQ D+ ++ P GVFT+Q + Sbjct: 295 VLQQRWTSFLKAQLLCSRPDDGF-PFNVLQ---DVFTLSPSPQDWRDTLFYGVFTSQWHR 350 Query: 322 -SIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAE-AY 379 + GSAVC F+M D+++VF G +KE W V VP PRPG C + E Sbjct: 351 GTTEGSAVCVFTMKDVQRVFSGLYKEVNRETQQWYTVTH-PVPTPRPGACITNSARERKI 409 Query: 380 KTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAISVDHSAGPYQNYTVI 439 +S+ PD L+F+K H LMD V + + RY+ ++V G + Y V+ Sbjct: 410 NSSLQLPDRVLNFLKDHFLMDGQV---RSRMLLLQPQARYQ--RVAVHRVPGLHHTYDVL 464 Query: 440 FVGSEAGMVLKVLAKTSPFSLNDSV-LLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHA 498 F+G+ G + K + S+ V ++EE++ ++ + V +L LD Sbjct: 465 FLGTGDGRLHKAV------SVGPRVHIIEELQIFS---------SGQPVQNLLLDTHRGL 509 Query: 499 LYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGSCGRVT---PGMLAEGYEQ 555 LY A S ++++P++ C Y SC C+ +RDPYC W S SC V+ P + + Q Sbjct: 510 LYAASHSGVVQVPMANCSLYRSC-GDCLLARDPYCAW-SGSSCKHVSLYQPQLATRPWIQ 567 Query: 556 DTEFGNTAHLGDCHDMEVSSSSVTT 580 D E + L + VS S V T Sbjct: 568 DIEGASAKDLCSASSV-VSPSFVPT 591 >gi|39777608 semaphorin 4B precursor [Homo sapiens] Length = 837 Score = 261 bits (666), Expect = 2e-69 Identities = 186/565 (32%), Positives = 284/565 (50%), Gaps = 72/565 (12%) Query: 52 ESQHRLDFQLMLKIRD--TLYIAGRDQVYTV--NLNEMPKTEVIPNKKLTWRSRQQDREN 107 E++H ++ +L RD TLY+ R+ ++ + NL+ +P E ++L W + + ++ Sbjct: 63 EAEHISNYTALLLSRDGRTLYVGAREALFALSSNLSFLPGGEY---QELLWGADAEKKQQ 119 Query: 108 CAMKGKHKD-ECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEIS----- 161 C+ KGK +C N+IK+ +P + +F CGT AF+PMC Y + +E Sbjct: 120 CSFKGKDPQRDCQNYIKILLPLSGSHLFTCGTAAFSPMCTYINMENFTLARDEKGNVLLE 179 Query: 162 -GLARCPFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSK--WI 218 G RCPFD + AL DG+LY+ TV+ F +D I RS +LR K +S W+ Sbjct: 180 DGKGRCPFDPNFKSTALVVDGELYTGTVSSFQGNDPAISRSQ----SLRPTKTESSLNWL 235 Query: 219 KEPHFLHAIEY----------GNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQR 268 ++P F+ + + +YFFF E E + SR+ARICK D GG +R Sbjct: 236 QDPAFVASAYIPESLGSLQGDDDKIYFFFSETGQEFEFFENTIVSRIARICKGDEGG-ER 294 Query: 269 VLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDIIQINGIPT------VVGVFTTQLN- 321 VL++ WTSFLKA+L CS P D F F+VLQ D+ ++ P GVFT+Q + Sbjct: 295 VLQQRWTSFLKAQLLCSRPDDGF-PFNVLQ---DVFTLSPSPQDWRDTLFYGVFTSQWHR 350 Query: 322 -SIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAE-AY 379 + GSAVC F+M D+++VF G +KE W V VP PRPG C + E Sbjct: 351 GTTEGSAVCVFTMKDVQRVFSGLYKEVNRETQQWYTVTH-PVPTPRPGACITNSARERKI 409 Query: 380 KTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAISVDHSAGPYQNYTVI 439 +S+ PD L+F+K H LMD V + + RY+ ++V G + Y V+ Sbjct: 410 NSSLQLPDRVLNFLKDHFLMDGQV---RSRMLLLQPQARYQ--RVAVHRVPGLHHTYDVL 464 Query: 440 FVGSEAGMVLKVLAKTSPFSLNDSV-LLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHA 498 F+G+ G + K + S+ V ++EE++ ++ + V +L LD Sbjct: 465 FLGTGDGRLHKAV------SVGPRVHIIEELQIFS---------SGQPVQNLLLDTHRGL 509 Query: 499 LYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGSCGRVT---PGMLAEGYEQ 555 LY A S ++++P++ C Y SC C+ +RDPYC W S SC V+ P + + Q Sbjct: 510 LYAASHSGVVQVPMANCSLYRSC-GDCLLARDPYCAW-SGSSCKHVSLYQPQLATRPWIQ 567 Query: 556 DTEFGNTAHLGDCHDMEVSSSSVTT 580 D E + L + VS S V T Sbjct: 568 DIEGASAKDLCSASSV-VSPSFVPT 591 >gi|9910362 semaphorin sem2 [Homo sapiens] Length = 782 Score = 258 bits (659), Expect = 1e-68 Identities = 186/560 (33%), Positives = 267/560 (47%), Gaps = 50/560 (8%) Query: 54 QHRLDFQLML--KIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMK 111 Q L+ Q M + RD L++ G D +Y++ L++ +++ W + RE C K Sbjct: 53 QGSLNLQAMYLDEYRDRLFLGGLDALYSLRLDQAWPDP----REVLWPPQPGQREECVRK 108 Query: 112 GKHK-DECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEI---------S 161 G+ EC NF++V P N + CGT AF P C L T+ + GE + S Sbjct: 109 GRDPLTECANFVRVLQPHNRTHLLACGTGAFQPTCA---LITVGHRGEHVLHLEPGSVES 165 Query: 162 GLARCPFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEP 221 G RCP + + + F DG+LY+ ADFL +A+I+RS G ALR+ D + +P Sbjct: 166 GRGRCPHEPSRPFASTFIDGELYTGLTADFLGREAMIFRSGGPRPALRSDS-DQSLLHDP 224 Query: 222 HFLHAIEY-------GNYVYFFFRE-IAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKH 273 F+ A + VYFFF E + SRV R+C ND GG QRVL Sbjct: 225 RFVMAARIPENSDQDNDKVYFFFSETVPSPDGGSNHVTVSRVGRVCVNDAGG-QRVLVNK 283 Query: 274 WTSFLKARLNCSVPGD--SFFYFDVLQSITDIIQINGIPT-VVGVFTTQLNSIPGSAVCA 330 W++FLKARL CSVPG + +FD L+ + + G V +F+T G AVC Sbjct: 284 WSTFLKARLVCSVPGPGGAETHFDQLEDVFLLWPKAGKSLEVYALFSTVSAVFQGFAVCV 343 Query: 331 FSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEA---YKTSIDFPD 387 + M DI +VF G F + P W KVP PRPG C A+ + ++ D+PD Sbjct: 344 YHMADIWEVFNGPFAHRDGPQHQWGPYG-GKVPFPRPGVCPSKMTAQPGRPFGSTKDYPD 402 Query: 388 ETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGM 447 E L F ++HPLM V P P KT + +L I VD Y VIF+G+++G Sbjct: 403 EVLQFARAHPLMFWPVRPRHGRPVLVKTHLAQQLHQIVVDRVEAEDGTYDVIFLGTDSGS 462 Query: 448 VLKVLAKTSPFSLN-DSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSC 506 VLKV+A + S + V+LEE++ + + + +++ LYV Sbjct: 463 VLKVIALQAGGSAEPEEVVLEELQVF---------KVPTPITEMEISVKRQMLYVGSRLG 513 Query: 507 IIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGSCGRVTPGMLAEGY-EQDTEFGNTA-- 563 + ++ L +CE YG+ C +RDPYC W SC P + + QD GN A Sbjct: 514 VAQLRLHQCETYGTACAECCLARDPYCAW-DGASCTHYRPSLGKRRFRRQDIRHGNPALQ 572 Query: 564 HLGDCHDMEVSSSSVTTMVY 583 LG + E TMVY Sbjct: 573 CLGQSQEEEAVGLVAATMVY 592 >gi|21361914 semaphorin B [Homo sapiens] Length = 761 Score = 233 bits (594), Expect = 4e-61 Identities = 167/519 (32%), Positives = 265/519 (51%), Gaps = 54/519 (10%) Query: 58 DFQLMLKIRD--TLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHK 115 DF +L D TLY+ R+ + +++ + P + N + W + + + CA K K Sbjct: 63 DFDTLLLSGDGNTLYVGAREAILALDIQD-PGVPRLKNM-IPWPASDRKKSECAFKKKSN 120 Query: 116 D-ECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEY----DGEEISGLARCPFDA 170 + +C NFI+V V N ++ CGT AF+P C + L + + + G + PFD Sbjct: 121 ETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQSPFDP 180 Query: 171 RQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIK-EPHFLHAIEY 229 + A+ DG LYS T+ +FL S+ ++ R++G L+T + +W+ + F+ AI Sbjct: 181 AHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNF-LRWLHHDASFVAAIPS 239 Query: 230 GNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGD 289 VYFFF E A E + + SRVAR+CKND+GG +++L+K WT+FLKA+L C+ PG Sbjct: 240 TQVVYFFFEETASEFDFFERLHTSRVARVCKNDVGG-EKLLQKKWTTFLKAQLLCTQPGQ 298 Query: 290 SFFYFDVLQSITDIIQINGIPTVVGVFTT--QLNSIPGSAVCAFSMDDIEKVFKGRFKEQ 347 F + ++ P + VFT+ Q+ SAVCAFS+ DIE+VFKG++KE Sbjct: 299 LPFNV-IRHAVLLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKEL 357 Query: 348 KTPDSVWTAV--PEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPP 405 S WT PE PRPG C+ + D+ L+F+K H LMD V Sbjct: 358 NKETSRWTTYRGPE---TNPRPGSCSVGPSS----------DKALTFMKDHFLMDEQV-- 402 Query: 406 IADEPWFTKTRVRYRLTAISVDHSAG-PYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSV 464 P K+ V Y T ++V+ + G ++ V+++G+ G + K + + + Sbjct: 403 -VGTPLLVKSGVEY--TRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGD----SSAH 455 Query: 465 LLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKS 524 L+EEI+ + + + V +LQL A++V FS + R+P + C Y SC Sbjct: 456 LVEEIQLF---------PDPEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVYESC-VD 505 Query: 525 CIASRDPYCGW--LSQGSCGRVTPGMLAEGYEQDTEFGN 561 C+ +RDP+C W S+ C P + ++QD E GN Sbjct: 506 CVLARDPHCAWDPESRTCCLLSAPNL--NSWKQDMERGN 542 >gi|19923279 semaphorin W [Homo sapiens] Length = 770 Score = 224 bits (570), Expect = 2e-58 Identities = 153/483 (31%), Positives = 247/483 (51%), Gaps = 41/483 (8%) Query: 68 TLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHNFIKVFVP 127 TLY+ RD ++ ++L P + P +++ W + R+NC KGK +DECHNF+++ Sbjct: 76 TLYVGARDTIFALSL---PFSGERP-RRIDWMVPEAHRQNCRKKGKKEDECHNFVQILAI 131 Query: 128 RNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFADGKLYSAT 187 N + CGT AF+P C +S + SG +CPF+ Q + A+ A G LY+AT Sbjct: 132 ANASHLLTCGTFAFDPKCGVIDVSRFQQVERLESGRGKCPFEPAQRSAAVMAGGVLYAAT 191 Query: 188 VADFLASDAVIYRSMGDGSA-LRTIKYDSKWIKEPHFLHAI-----EYG-----NYVYFF 236 V ++L ++ +I R++G +RT S W+ P F+ A+ E+G + +YFF Sbjct: 192 VKNYLGTEPIITRAVGRAEDWIRTDTLPS-WLNAPAFVAAVALSPAEWGDEDGDDEIYFF 250 Query: 237 FREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDV 296 F E + ++ + RVAR+C D+GG ++ L++ WT+FLKA L C P + V Sbjct: 251 FTETSRAFDSYERIKVPRVARVCAGDLGG-RKTLQQRWTTFLKADLLCPGP-EHGRASSV 308 Query: 297 LQSITDIIQI--NGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVW 354 LQ + + G P G+F++Q SAVCAF DI V G F+E K + Sbjct: 309 LQDVAVLRPELGAGTPIFYGIFSSQWEGATISAVCAFRPQDIRTVLNGPFRELKHDCNRG 368 Query: 355 TAVPEDKVPKPRPGCCAKHGL-AEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFT 413 V ++ VP+PRPG C + + + +S+ PD L+FI+ HPLMD V P P Sbjct: 369 LPVVDNDVPQPRPGECITNNMKLRHFGSSLSLPDRVLTFIRDHPLMDRPVFPADGHPLLV 428 Query: 414 KTRVRY-RLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAY 472 T Y R+ A V +G + Y V+++G+E G + + + + S +LE++ + Sbjct: 429 TTDTAYLRVVAHRVTSLSG--KEYDVLYLGTEDGHLHRAVRIGAQLS-----VLEDLALF 481 Query: 473 NHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPY 532 E + V +++L H L V + + ++ + C R SC + CI ++DP Sbjct: 482 ---------PEPQPVENMKL--YHSWLLVGSRTEVTQVNTTNCGRLQSCSE-CILAQDPV 529 Query: 533 CGW 535 C W Sbjct: 530 CAW 532 >gi|28872814 semaphorin 4G [Homo sapiens] Length = 843 Score = 221 bits (564), Expect = 1e-57 Identities = 164/541 (30%), Positives = 253/541 (46%), Gaps = 59/541 (10%) Query: 18 LRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQLMLKIRDTLYIAGRDQV 77 LR S D P T+ Y F+G+ + L+ + L + R + Sbjct: 23 LRRPSRELDATPRMTIPYEELSGTRHFKGQAQNYSTL------LLEEASARLLVGARGAL 76 Query: 78 YTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKD-ECHNFIKVFVPRNDEMVFVC 136 ++++ N++ +K++ W + + + C KGK+ EC N ++ N ++ C Sbjct: 77 FSLSANDIGDGA---HKEIHWEASPEMQSKCHQKGKNNQTECFNHVRFLQRLNSTHLYAC 133 Query: 137 GTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFADGKLYSATVADFLASDA 196 GT+AF P+C G +CP+D + L DG LY+AT +F + Sbjct: 134 GTHAFQPLCAAIDAEAFTLPTSFEEGKEKCPYDPARGFTGLIIDGGLYTATRYEFRSIPD 193 Query: 197 VIYRSMGDGSALRTIKYDSKWIKEPHFLH----------AIEYGNYVYFFFREIAVEHNN 246 + R +LRT + W+ + F+ A+ + VY+FF E A E + Sbjct: 194 I--RRSRHPHSLRTEETPMHWLNDAEFVFSVLVRESKASAVGDDDKVYYFFTERATEEGS 251 Query: 247 LGKAVYSR-------VARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQS 299 G SR VAR+CK D+GG +++L+K WTSFLKARL C +P ++ L+ Sbjct: 252 -GSFTQSRSSHRVARVARVCKGDLGG-KKILQKKWTSFLKARLICHIP-----LYETLRG 304 Query: 300 ITDI-IQINGIPTVVGVFT--TQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTA 356 + + + + FT TQ ++ SA+C + + +I+ VF G + E + W Sbjct: 305 VCSLDAETSSRTHFYAAFTLSTQWKTLEASAICRYDLAEIQAVFAGPYMEYQDGSRRWGR 364 Query: 357 VPEDKVPKPRPGCCAKHGL-AEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKT 415 E VP+PRPG C L ++ Y +S D P L F+K HPLM V P P K Sbjct: 365 Y-EGGVPEPRPGSCITDSLRSQGYNSSQDLPSLVLDFVKLHPLMARPVVPTRGRPLLLKR 423 Query: 416 RVRY-RLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNH 474 +RY LT V AGP Y ++F+G+ G + K + S ++EE + + Sbjct: 424 NIRYTHLTGTPVTTPAGP--TYDLLFLGTADGWIHKAVVLGSGMH-----IIEETQVFRE 476 Query: 475 AKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCG 534 ++ S EN VISL H+LYV S +I++PLS C RY SC CI +RDPYCG Sbjct: 477 SQ-SVEN----LVISLL----QHSLYVGAPSGVIQLPLSSCSRYRSC-YDCILARDPYCG 526 Query: 535 W 535 W Sbjct: 527 W 527 >gi|4504237 semaphorin 7A isoform 1 preproprotein [Homo sapiens] Length = 666 Score = 134 bits (337), Expect = 2e-31 Identities = 126/441 (28%), Positives = 192/441 (43%), Gaps = 59/441 (13%) Query: 115 KDECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTN 174 K +C N+I + + R E + CGTNA +P C T+ GE + G A PF + + Sbjct: 123 KRDCENYITL-LERRSEGLLACGTNARHPSCWNLVNGTVVPLGE-MRGYA--PFSPDENS 178 Query: 175 VALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAI------E 228 + LF ++YS +R + S L T ++ P F+ A Sbjct: 179 LVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYT---SDTVMQNPQFIKATIVHQDQA 235 Query: 229 YGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPG 288 Y + +Y+FFRE + N SRVA++C+ D GG + W +FLKA L CS Sbjct: 236 YDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVCSDAA 295 Query: 289 DSFFYFDVLQSITDIIQING---IPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFK 345 + F+ LQ + + +G V GVF+ N SAVC +S+ DI+KVF R Sbjct: 296 TN-KNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY---SAVCVYSLGDIDKVF--RTS 349 Query: 346 EQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPP 405 K S +P PRPG C P ET HP + V P Sbjct: 350 SLKGYHS--------SLPNPRPGKC--------LPDQQPIPTETFQVADRHPEVAQRVEP 393 Query: 406 IA--DEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVL---AKTSPFSL 460 + P F ++ Y+ A+ A + + V+++ ++ G + KV+ + F+ Sbjct: 394 MGPLKTPLF-HSKYHYQKVAVH-RMQASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAF 451 Query: 461 NDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGS 520 N + EI+ + A + ++ LD + LYV+ + ++PL CE YG Sbjct: 452 N----IMEIQPFRRAAA---------IQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGG 498 Query: 521 CKKSCIASRDPYCGWLSQGSC 541 C+ SRDPYCGW QG C Sbjct: 499 GCHGCLMSRDPYCGW-DQGRC 518 >gi|225637520 semaphorin 7A isoform 2 preproprotein [Homo sapiens] Length = 652 Score = 133 bits (335), Expect = 4e-31 Identities = 125/441 (28%), Positives = 192/441 (43%), Gaps = 59/441 (13%) Query: 115 KDECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTN 174 + +C N+I + + R E + CGTNA +P C T+ GE + G A PF + + Sbjct: 109 RTDCENYITL-LERRSEGLLACGTNARHPSCWNLVNGTVVPLGE-MRGYA--PFSPDENS 164 Query: 175 VALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAI------E 228 + LF ++YS +R + S L T ++ P F+ A Sbjct: 165 LVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYT---SDTVMQNPQFIKATIVHQDQA 221 Query: 229 YGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPG 288 Y + +Y+FFRE + N SRVA++C+ D GG + W +FLKA L CS Sbjct: 222 YDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVCSDAA 281 Query: 289 DSFFYFDVLQSITDIIQING---IPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFK 345 + F+ LQ + + +G V GVF+ N SAVC +S+ DI+KVF R Sbjct: 282 TN-KNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY---SAVCVYSLGDIDKVF--RTS 335 Query: 346 EQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPP 405 K S +P PRPG C P ET HP + V P Sbjct: 336 SLKGYHS--------SLPNPRPGKC--------LPDQQPIPTETFQVADRHPEVAQRVEP 379 Query: 406 IA--DEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVL---AKTSPFSL 460 + P F ++ Y+ A+ A + + V+++ ++ G + KV+ + F+ Sbjct: 380 MGPLKTPLF-HSKYHYQKVAVH-RMQASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAF 437 Query: 461 NDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGS 520 N + EI+ + A + ++ LD + LYV+ + ++PL CE YG Sbjct: 438 N----IMEIQPFRRAAA---------IQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGG 484 Query: 521 CKKSCIASRDPYCGWLSQGSC 541 C+ SRDPYCGW QG C Sbjct: 485 GCHGCLMSRDPYCGW-DQGRC 504 >gi|225637524 semaphorin 7A isoform 3 [Homo sapiens] Length = 501 Score = 116 bits (291), Expect = 5e-26 Identities = 108/389 (27%), Positives = 166/389 (42%), Gaps = 55/389 (14%) Query: 167 PFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHA 226 PF + ++ LF ++YS +R + S L T ++ P F+ A Sbjct: 6 PFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYT---SDTVMQNPQFIKA 62 Query: 227 I------EYGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKA 280 Y + +Y+FFRE + N SRVA++C+ D GG + W +FLKA Sbjct: 63 TIVHQDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKA 122 Query: 281 RLNCSVPGDSFFYFDVLQSITDIIQING---IPTVVGVFTTQLNSIPGSAVCAFSMDDIE 337 L CS + F+ LQ + + +G V GVF+ N SAVC +S+ DI+ Sbjct: 123 MLVCSDAATN-KNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY---SAVCVYSLGDID 178 Query: 338 KVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHP 397 KVF R K S +P PRPG C P ET HP Sbjct: 179 KVF--RTSSLKGYHS--------SLPNPRPGKC--------LPDQQPIPTETFQVADRHP 220 Query: 398 LMDSAVPPIA--DEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVL--- 452 + V P+ P F ++ Y+ A+ A + + V+++ ++ G + KV+ Sbjct: 221 EVAQRVEPMGPLKTPLF-HSKYHYQKVAVH-RMQASHGETFHVLYLTTDRGTIHKVVEPG 278 Query: 453 AKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPL 512 + F+ N + EI+ + A + ++ LD + LYV+ + ++PL Sbjct: 279 EQEHSFAFN----IMEIQPFRRAAA---------IQTMSLDAERRKLYVSSQWEVSQVPL 325 Query: 513 SRCERYGSCKKSCIASRDPYCGWLSQGSC 541 CE YG C+ SRDPYCGW QG C Sbjct: 326 DLCEVYGGGCHGCLMSRDPYCGW-DQGRC 353 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.321 0.135 0.416 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 23,137,571 Number of Sequences: 37866 Number of extensions: 1022174 Number of successful extensions: 2278 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 37 Number of HSP's successfully gapped in prelim test: 9 Number of HSP's that attempted gapping in prelim test: 2049 Number of HSP's gapped (non-prelim): 59 length of query: 597 length of database: 18,247,518 effective HSP length: 108 effective length of query: 489 effective length of database: 14,157,990 effective search space: 6923257110 effective search space used: 6923257110 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.