Search of human proteins with 24234738

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens]
         (1017 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens]         2088   0.0  
gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens]         2040   0.0  
gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens]         2037   0.0  
gi|24234729 semaphorin 6D isoform 1 precursor [Homo sapiens]         2028   0.0  
gi|24234744 semaphorin 6D isoform 5 precursor [Homo sapiens]         1180   0.0  
gi|24234732 semaphorin 6D isoform 6 precursor [Homo sapiens]          976   0.0  
gi|11991660 sema domain, transmembrane domain (TM), and cytoplas...   877   0.0  
gi|16306552 semaphorin Y [Homo sapiens]                               633   0.0  
gi|19718780 semaphorin 6B precursor [Homo sapiens]                    631   0.0  
gi|41406086 semaphorin 3D [Homo sapiens]                              313   5e-85
gi|91982767 semaphorin 5B isoform 1 [Homo sapiens]                    308   1e-83
gi|5174673 semaphorin 3A precursor [Homo sapiens]                     305   1e-82
gi|6912650 semaphorin 3E [Homo sapiens]                               298   1e-80
gi|147904700 semaphorin 5A [Homo sapiens]                             295   1e-79
gi|188497703 semaphorin 3F [Homo sapiens]                             294   3e-79
gi|4759092 semaphorin 3B isoform 1 precursor [Homo sapiens]           289   1e-77
gi|5454048 semaphorin 3C [Homo sapiens]                               288   1e-77
gi|54607089 semaphorin 3B isoform 2 precursor [Homo sapiens]          285   2e-76
gi|214010220 semaphorin 4D isoform 2 [Homo sapiens]                   281   3e-75
gi|214010218 semaphorin 4D isoform 1 [Homo sapiens]                   281   3e-75
gi|157388902 semaphorin 4C [Homo sapiens]                             268   2e-71
gi|39777610 semaphorin 4B precursor [Homo sapiens]                    263   8e-70
gi|39777608 semaphorin 4B precursor [Homo sapiens]                    263   8e-70
gi|9910362 semaphorin sem2 [Homo sapiens]                             254   4e-67
gi|21361914 semaphorin B [Homo sapiens]                               233   7e-61
gi|19923279 semaphorin W [Homo sapiens]                               224   4e-58
gi|28872814 semaphorin 4G [Homo sapiens]                              221   2e-57
gi|4504237 semaphorin 7A isoform 1 preproprotein [Homo sapiens]       134   4e-31
gi|225637520 semaphorin 7A isoform 2 preproprotein [Homo sapiens]     133   7e-31
gi|225637524 semaphorin 7A isoform 3 [Homo sapiens]                   116   9e-26

>gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens]
          Length = 1017

 Score = 2088 bits (5409), Expect = 0.0
 Identities = 1017/1017 (100%), Positives = 1017/1017 (100%)

Query: 1    MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQ 60
            MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQ
Sbjct: 1    MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQ 60

Query: 61   LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHN 120
            LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHN
Sbjct: 61   LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHN 120

Query: 121  FIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFAD 180
            FIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFAD
Sbjct: 121  FIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFAD 180

Query: 181  GKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREI 240
            GKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREI
Sbjct: 181  GKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREI 240

Query: 241  AVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSI 300
            AVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSI
Sbjct: 241  AVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSI 300

Query: 301  TDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPED 360
            TDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPED
Sbjct: 301  TDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPED 360

Query: 361  KVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYR 420
            KVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYR
Sbjct: 361  KVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYR 420

Query: 421  LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAE 480
            LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAE
Sbjct: 421  LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAE 480

Query: 481  NEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGS 540
            NEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGS
Sbjct: 481  NEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGS 540

Query: 541  CGRVTPGMLAEGYEQDTEFGNTAHLGDCHEILPTSTTPDYKIFGGPTSGVRWEVQSGESN 600
            CGRVTPGMLAEGYEQDTEFGNTAHLGDCHEILPTSTTPDYKIFGGPTSGVRWEVQSGESN
Sbjct: 541  CGRVTPGMLAEGYEQDTEFGNTAHLGDCHEILPTSTTPDYKIFGGPTSGVRWEVQSGESN 600

Query: 601  QMVHMNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHKDAESAQSCTDSSGSFAK 660
            QMVHMNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHKDAESAQSCTDSSGSFAK
Sbjct: 601  QMVHMNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHKDAESAQSCTDSSGSFAK 660

Query: 661  LNGLFDSPVKEYQQNIDSPKLYSNLLTSRKELPPNGDTKSMVMDHRGQPPELAALPTPES 720
            LNGLFDSPVKEYQQNIDSPKLYSNLLTSRKELPPNGDTKSMVMDHRGQPPELAALPTPES
Sbjct: 661  LNGLFDSPVKEYQQNIDSPKLYSNLLTSRKELPPNGDTKSMVMDHRGQPPELAALPTPES 720

Query: 721  TPVLHQKTLQAMKSHSEKAHGHGASRKETPQFFPSSPPPHSPLSHGHIPSAIVLPNATHD 780
            TPVLHQKTLQAMKSHSEKAHGHGASRKETPQFFPSSPPPHSPLSHGHIPSAIVLPNATHD
Sbjct: 721  TPVLHQKTLQAMKSHSEKAHGHGASRKETPQFFPSSPPPHSPLSHGHIPSAIVLPNATHD 780

Query: 781  YNTSFSNSNAHKAEKKLQNIDHPLTKSSSKRDHRRSVDSRNTLNDLLKHLNDPNSNPKAI 840
            YNTSFSNSNAHKAEKKLQNIDHPLTKSSSKRDHRRSVDSRNTLNDLLKHLNDPNSNPKAI
Sbjct: 781  YNTSFSNSNAHKAEKKLQNIDHPLTKSSSKRDHRRSVDSRNTLNDLLKHLNDPNSNPKAI 840

Query: 841  MGDIQMAHQNLMLDPMGSMSEVPPKVPNREASLYSPPSTLPRNSPTKRVDVPTTPGVPMT 900
            MGDIQMAHQNLMLDPMGSMSEVPPKVPNREASLYSPPSTLPRNSPTKRVDVPTTPGVPMT
Sbjct: 841  MGDIQMAHQNLMLDPMGSMSEVPPKVPNREASLYSPPSTLPRNSPTKRVDVPTTPGVPMT 900

Query: 901  SLERQRGYHKNSSQRHSISAMPKNLNSPNGVLLSRQPSMNRGGYMPTPTGAKVDYIQGTP 960
            SLERQRGYHKNSSQRHSISAMPKNLNSPNGVLLSRQPSMNRGGYMPTPTGAKVDYIQGTP
Sbjct: 901  SLERQRGYHKNSSQRHSISAMPKNLNSPNGVLLSRQPSMNRGGYMPTPTGAKVDYIQGTP 960

Query: 961  VSVHLQPSLSRQSSYTSNGTLPRTGLKRTPSLKPDVPPKPSFVPQTPSVRPLNKYTY 1017
            VSVHLQPSLSRQSSYTSNGTLPRTGLKRTPSLKPDVPPKPSFVPQTPSVRPLNKYTY
Sbjct: 961  VSVHLQPSLSRQSSYTSNGTLPRTGLKRTPSLKPDVPPKPSFVPQTPSVRPLNKYTY 1017


>gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens]
          Length = 1073

 Score = 2040 bits (5284), Expect = 0.0
 Identities = 1010/1073 (94%), Positives = 1011/1073 (94%), Gaps = 56/1073 (5%)

Query: 1    MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQ 60
            MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQ
Sbjct: 1    MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQ 60

Query: 61   LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHN 120
            LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHN
Sbjct: 61   LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHN 120

Query: 121  FIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFAD 180
            FIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFAD
Sbjct: 121  FIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFAD 180

Query: 181  GKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREI 240
            GKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREI
Sbjct: 181  GKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREI 240

Query: 241  AVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSI 300
            AVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSI
Sbjct: 241  AVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSI 300

Query: 301  TDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPED 360
            TDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPED
Sbjct: 301  TDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPED 360

Query: 361  KVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYR 420
            KVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYR
Sbjct: 361  KVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYR 420

Query: 421  LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAE 480
            LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAE
Sbjct: 421  LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAE 480

Query: 481  NEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGS 540
            NEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGS
Sbjct: 481  NEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGS 540

Query: 541  CGRVTPGMLAEGYEQDTEFGNTAHLGDCHEILPTSTT----------------------- 577
            CGRVTPGMLAEGYEQDTEFGNTAHLGDCHEILPTSTT                       
Sbjct: 541  CGRVTPGMLAEGYEQDTEFGNTAHLGDCHEILPTSTTPDYKIFGGPTSDMEVSSSSVTTM 600

Query: 578  -----------------------------PDYKIFGGPTSG----VRWEVQSGESNQMVH 604
                                         P+   F  P SG    VRWEVQSGESNQMVH
Sbjct: 601  ASIPEITPKVIDTWRPKLTSSRKFVVQDDPNTSDFTDPLSGIPKGVRWEVQSGESNQMVH 660

Query: 605  MNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHKDAESAQSCTDSSGSFAKLNGL 664
            MNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHKDAESAQSCTDSSGSFAKLNGL
Sbjct: 661  MNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHKDAESAQSCTDSSGSFAKLNGL 720

Query: 665  FDSPVKEYQQNIDSPKLYSNLLTSRKELPPNGDTKSMVMDHRGQPPELAALPTPESTPVL 724
            FDSPVKEYQQNIDSPKLYSNLLTSRKELPPNGDTKSMVMDHRGQPPELAALPTPESTPVL
Sbjct: 721  FDSPVKEYQQNIDSPKLYSNLLTSRKELPPNGDTKSMVMDHRGQPPELAALPTPESTPVL 780

Query: 725  HQKTLQAMKSHSEKAHGHGASRKETPQFFPSSPPPHSPLSHGHIPSAIVLPNATHDYNTS 784
            HQKTLQAMKSHSEKAHGHGASRKETPQFFPSSPPPHSPLSHGHIPSAIVLPNATHDYNTS
Sbjct: 781  HQKTLQAMKSHSEKAHGHGASRKETPQFFPSSPPPHSPLSHGHIPSAIVLPNATHDYNTS 840

Query: 785  FSNSNAHKAEKKLQNIDHPLTKSSSKRDHRRSVDSRNTLNDLLKHLNDPNSNPKAIMGDI 844
            FSNSNAHKAEKKLQNIDHPLTKSSSKRDHRRSVDSRNTLNDLLKHLNDPNSNPKAIMGDI
Sbjct: 841  FSNSNAHKAEKKLQNIDHPLTKSSSKRDHRRSVDSRNTLNDLLKHLNDPNSNPKAIMGDI 900

Query: 845  QMAHQNLMLDPMGSMSEVPPKVPNREASLYSPPSTLPRNSPTKRVDVPTTPGVPMTSLER 904
            QMAHQNLMLDPMGSMSEVPPKVPNREASLYSPPSTLPRNSPTKRVDVPTTPGVPMTSLER
Sbjct: 901  QMAHQNLMLDPMGSMSEVPPKVPNREASLYSPPSTLPRNSPTKRVDVPTTPGVPMTSLER 960

Query: 905  QRGYHKNSSQRHSISAMPKNLNSPNGVLLSRQPSMNRGGYMPTPTGAKVDYIQGTPVSVH 964
            QRGYHKNSSQRHSISAMPKNLNSPNGVLLSRQPSMNRGGYMPTPTGAKVDYIQGTPVSVH
Sbjct: 961  QRGYHKNSSQRHSISAMPKNLNSPNGVLLSRQPSMNRGGYMPTPTGAKVDYIQGTPVSVH 1020

Query: 965  LQPSLSRQSSYTSNGTLPRTGLKRTPSLKPDVPPKPSFVPQTPSVRPLNKYTY 1017
            LQPSLSRQSSYTSNGTLPRTGLKRTPSLKPDVPPKPSFVPQTPSVRPLNKYTY
Sbjct: 1021 LQPSLSRQSSYTSNGTLPRTGLKRTPSLKPDVPPKPSFVPQTPSVRPLNKYTY 1073


>gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens]
          Length = 998

 Score = 2037 bits (5277), Expect = 0.0
 Identities = 998/1017 (98%), Positives = 998/1017 (98%), Gaps = 19/1017 (1%)

Query: 1    MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQ 60
            MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQ
Sbjct: 1    MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQ 60

Query: 61   LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHN 120
            LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHN
Sbjct: 61   LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHN 120

Query: 121  FIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFAD 180
            FIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFAD
Sbjct: 121  FIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFAD 180

Query: 181  GKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREI 240
            GKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREI
Sbjct: 181  GKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREI 240

Query: 241  AVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSI 300
            AVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSI
Sbjct: 241  AVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSI 300

Query: 301  TDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPED 360
            TDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPED
Sbjct: 301  TDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPED 360

Query: 361  KVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYR 420
            KVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYR
Sbjct: 361  KVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYR 420

Query: 421  LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAE 480
            LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAE
Sbjct: 421  LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAE 480

Query: 481  NEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGS 540
            NEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGS
Sbjct: 481  NEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGS 540

Query: 541  CGRVTPGMLAEGYEQDTEFGNTAHLGDCHEILPTSTTPDYKIFGGPTSGVRWEVQSGESN 600
            CGRVTPGMLAEGYEQDTEFGNTAHLGDCH                   GVRWEVQSGESN
Sbjct: 541  CGRVTPGMLAEGYEQDTEFGNTAHLGDCH-------------------GVRWEVQSGESN 581

Query: 601  QMVHMNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHKDAESAQSCTDSSGSFAK 660
            QMVHMNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHKDAESAQSCTDSSGSFAK
Sbjct: 582  QMVHMNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHKDAESAQSCTDSSGSFAK 641

Query: 661  LNGLFDSPVKEYQQNIDSPKLYSNLLTSRKELPPNGDTKSMVMDHRGQPPELAALPTPES 720
            LNGLFDSPVKEYQQNIDSPKLYSNLLTSRKELPPNGDTKSMVMDHRGQPPELAALPTPES
Sbjct: 642  LNGLFDSPVKEYQQNIDSPKLYSNLLTSRKELPPNGDTKSMVMDHRGQPPELAALPTPES 701

Query: 721  TPVLHQKTLQAMKSHSEKAHGHGASRKETPQFFPSSPPPHSPLSHGHIPSAIVLPNATHD 780
            TPVLHQKTLQAMKSHSEKAHGHGASRKETPQFFPSSPPPHSPLSHGHIPSAIVLPNATHD
Sbjct: 702  TPVLHQKTLQAMKSHSEKAHGHGASRKETPQFFPSSPPPHSPLSHGHIPSAIVLPNATHD 761

Query: 781  YNTSFSNSNAHKAEKKLQNIDHPLTKSSSKRDHRRSVDSRNTLNDLLKHLNDPNSNPKAI 840
            YNTSFSNSNAHKAEKKLQNIDHPLTKSSSKRDHRRSVDSRNTLNDLLKHLNDPNSNPKAI
Sbjct: 762  YNTSFSNSNAHKAEKKLQNIDHPLTKSSSKRDHRRSVDSRNTLNDLLKHLNDPNSNPKAI 821

Query: 841  MGDIQMAHQNLMLDPMGSMSEVPPKVPNREASLYSPPSTLPRNSPTKRVDVPTTPGVPMT 900
            MGDIQMAHQNLMLDPMGSMSEVPPKVPNREASLYSPPSTLPRNSPTKRVDVPTTPGVPMT
Sbjct: 822  MGDIQMAHQNLMLDPMGSMSEVPPKVPNREASLYSPPSTLPRNSPTKRVDVPTTPGVPMT 881

Query: 901  SLERQRGYHKNSSQRHSISAMPKNLNSPNGVLLSRQPSMNRGGYMPTPTGAKVDYIQGTP 960
            SLERQRGYHKNSSQRHSISAMPKNLNSPNGVLLSRQPSMNRGGYMPTPTGAKVDYIQGTP
Sbjct: 882  SLERQRGYHKNSSQRHSISAMPKNLNSPNGVLLSRQPSMNRGGYMPTPTGAKVDYIQGTP 941

Query: 961  VSVHLQPSLSRQSSYTSNGTLPRTGLKRTPSLKPDVPPKPSFVPQTPSVRPLNKYTY 1017
            VSVHLQPSLSRQSSYTSNGTLPRTGLKRTPSLKPDVPPKPSFVPQTPSVRPLNKYTY
Sbjct: 942  VSVHLQPSLSRQSSYTSNGTLPRTGLKRTPSLKPDVPPKPSFVPQTPSVRPLNKYTY 998


>gi|24234729 semaphorin 6D isoform 1 precursor [Homo sapiens]
          Length = 1011

 Score = 2028 bits (5253), Expect = 0.0
 Identities = 998/1030 (96%), Positives = 998/1030 (96%), Gaps = 32/1030 (3%)

Query: 1    MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQ 60
            MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQ
Sbjct: 1    MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQ 60

Query: 61   LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHN 120
            LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHN
Sbjct: 61   LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHN 120

Query: 121  FIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFAD 180
            FIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFAD
Sbjct: 121  FIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFAD 180

Query: 181  GKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREI 240
            GKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREI
Sbjct: 181  GKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREI 240

Query: 241  AVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSI 300
            AVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSI
Sbjct: 241  AVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSI 300

Query: 301  TDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPED 360
            TDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPED
Sbjct: 301  TDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPED 360

Query: 361  KVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYR 420
            KVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYR
Sbjct: 361  KVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYR 420

Query: 421  LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAE 480
            LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAE
Sbjct: 421  LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAE 480

Query: 481  NEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGS 540
            NEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGS
Sbjct: 481  NEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGS 540

Query: 541  CGRVTPGML-------------AEGYEQDTEFGNTAHLGDCHEILPTSTTPDYKIFGGPT 587
            CGRVTPGML             AEGYEQDTEFGNTAHLGDCH                  
Sbjct: 541  CGRVTPGMLLLTEDFFAFHNHSAEGYEQDTEFGNTAHLGDCH------------------ 582

Query: 588  SGVRWEVQSGESNQMVHMNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHKDAES 647
             GVRWEVQSGESNQMVHMNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHKDAES
Sbjct: 583  -GVRWEVQSGESNQMVHMNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHKDAES 641

Query: 648  AQSCTDSSGSFAKLNGLFDSPVKEYQQNIDSPKLYSNLLTSRKELPPNGDTKSMVMDHRG 707
            AQSCTDSSGSFAKLNGLFDSPVKEYQQNIDSPKLYSNLLTSRKELPPNGDTKSMVMDHRG
Sbjct: 642  AQSCTDSSGSFAKLNGLFDSPVKEYQQNIDSPKLYSNLLTSRKELPPNGDTKSMVMDHRG 701

Query: 708  QPPELAALPTPESTPVLHQKTLQAMKSHSEKAHGHGASRKETPQFFPSSPPPHSPLSHGH 767
            QPPELAALPTPESTPVLHQKTLQAMKSHSEKAHGHGASRKETPQFFPSSPPPHSPLSHGH
Sbjct: 702  QPPELAALPTPESTPVLHQKTLQAMKSHSEKAHGHGASRKETPQFFPSSPPPHSPLSHGH 761

Query: 768  IPSAIVLPNATHDYNTSFSNSNAHKAEKKLQNIDHPLTKSSSKRDHRRSVDSRNTLNDLL 827
            IPSAIVLPNATHDYNTSFSNSNAHKAEKKLQNIDHPLTKSSSKRDHRRSVDSRNTLNDLL
Sbjct: 762  IPSAIVLPNATHDYNTSFSNSNAHKAEKKLQNIDHPLTKSSSKRDHRRSVDSRNTLNDLL 821

Query: 828  KHLNDPNSNPKAIMGDIQMAHQNLMLDPMGSMSEVPPKVPNREASLYSPPSTLPRNSPTK 887
            KHLNDPNSNPKAIMGDIQMAHQNLMLDPMGSMSEVPPKVPNREASLYSPPSTLPRNSPTK
Sbjct: 822  KHLNDPNSNPKAIMGDIQMAHQNLMLDPMGSMSEVPPKVPNREASLYSPPSTLPRNSPTK 881

Query: 888  RVDVPTTPGVPMTSLERQRGYHKNSSQRHSISAMPKNLNSPNGVLLSRQPSMNRGGYMPT 947
            RVDVPTTPGVPMTSLERQRGYHKNSSQRHSISAMPKNLNSPNGVLLSRQPSMNRGGYMPT
Sbjct: 882  RVDVPTTPGVPMTSLERQRGYHKNSSQRHSISAMPKNLNSPNGVLLSRQPSMNRGGYMPT 941

Query: 948  PTGAKVDYIQGTPVSVHLQPSLSRQSSYTSNGTLPRTGLKRTPSLKPDVPPKPSFVPQTP 1007
            PTGAKVDYIQGTPVSVHLQPSLSRQSSYTSNGTLPRTGLKRTPSLKPDVPPKPSFVPQTP
Sbjct: 942  PTGAKVDYIQGTPVSVHLQPSLSRQSSYTSNGTLPRTGLKRTPSLKPDVPPKPSFVPQTP 1001

Query: 1008 SVRPLNKYTY 1017
            SVRPLNKYTY
Sbjct: 1002 SVRPLNKYTY 1011


>gi|24234744 semaphorin 6D isoform 5 precursor [Homo sapiens]
          Length = 597

 Score = 1180 bits (3052), Expect = 0.0
 Identities = 572/588 (97%), Positives = 580/588 (98%)

Query: 1   MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQ 60
           MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQ
Sbjct: 1   MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQ 60

Query: 61  LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHN 120
           LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHN
Sbjct: 61  LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHN 120

Query: 121 FIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFAD 180
           FIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFAD
Sbjct: 121 FIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFAD 180

Query: 181 GKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREI 240
           GKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREI
Sbjct: 181 GKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREI 240

Query: 241 AVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSI 300
           AVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSI
Sbjct: 241 AVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSI 300

Query: 301 TDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPED 360
           TDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPED
Sbjct: 301 TDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPED 360

Query: 361 KVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYR 420
           KVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYR
Sbjct: 361 KVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYR 420

Query: 421 LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAE 480
           LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAE
Sbjct: 421 LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAE 480

Query: 481 NEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGS 540
           NEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGS
Sbjct: 481 NEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGS 540

Query: 541 CGRVTPGMLAEGYEQDTEFGNTAHLGDCHEILPTSTTPDYKIFGGPTS 588
           CGRVTPGMLAEGYEQDTEFGNTAHLGDCH++  +S++    ++ G +S
Sbjct: 541 CGRVTPGMLAEGYEQDTEFGNTAHLGDCHDMEVSSSSVTTMVYDGKSS 588


>gi|24234732 semaphorin 6D isoform 6 precursor [Homo sapiens]
          Length = 476

 Score =  976 bits (2522), Expect = 0.0
 Identities = 476/476 (100%), Positives = 476/476 (100%)

Query: 1   MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQ 60
           MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQ
Sbjct: 1   MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQ 60

Query: 61  LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHN 120
           LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHN
Sbjct: 61  LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHN 120

Query: 121 FIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFAD 180
           FIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFAD
Sbjct: 121 FIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFAD 180

Query: 181 GKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREI 240
           GKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREI
Sbjct: 181 GKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREI 240

Query: 241 AVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSI 300
           AVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSI
Sbjct: 241 AVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSI 300

Query: 301 TDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPED 360
           TDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPED
Sbjct: 301 TDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPED 360

Query: 361 KVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYR 420
           KVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYR
Sbjct: 361 KVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYR 420

Query: 421 LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAK 476
           LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAK
Sbjct: 421 LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAK 476


>gi|11991660 sema domain, transmembrane domain (TM), and cytoplasmic
            domain, (semaphorin) 6A [Homo sapiens]
          Length = 1030

 Score =  877 bits (2267), Expect = 0.0
 Identities = 497/1067 (46%), Positives = 654/1067 (61%), Gaps = 109/1067 (10%)

Query: 8    AYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRG-RPSGNESQ-HRLDFQLMLKI 65
            A +L   +       FPED EP++    +Y++QYPVF G +P  N +Q HRLD Q+++ +
Sbjct: 5    ALLLYFTLLHFAGAGFPEDSEPISISHGNYTKQYPVFVGHKPGRNTTQRHRLDIQMIMIM 64

Query: 66   RDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHNFIKVF 125
              TLYIA RD +YTV+++     E+  +KKLTW+SRQ D + C MKGKHKDECHNFIKV 
Sbjct: 65   NGTLYIAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKGKHKDECHNFIKVL 124

Query: 126  VPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFADGKLYS 185
            + +ND+ +FVCGTNAFNP CR Y++ TLE  G+E SG+ARCP+DA+  NVALFADGKLYS
Sbjct: 125  LKKNDDALFVCGTNAFNPSCRNYKMDTLEPFGDEFSGMARCPYDAKHANVALFADGKLYS 184

Query: 186  ATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIAVEHN 245
            ATV DFLA DAVIYRS+G+   LRT+K+DSKW+KEP+F+ A++YG+Y+YFFFREIAVE+N
Sbjct: 185  ATVTDFLAIDAVIYRSLGESPTLRTVKHDSKWLKEPYFVQAVDYGDYIYFFFREIAVEYN 244

Query: 246  NLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDIIQ 305
             +GK V+ RVA++CKNDMGGSQRVLEK WTSFLKARLNCSVPGDS FYF++LQ++TD+I+
Sbjct: 245  TMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNILQAVTDVIR 304

Query: 306  INGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKP 365
            ING   V+  F+T  NSIPGSAVCA+ M DI  VF GRFKEQK+PDS WT VP+++VPKP
Sbjct: 305  INGRDVVLATFSTPYNSIPGSAVCAYDMLDIASVFTGRFKEQKSPDSTWTPVPDERVPKP 364

Query: 366  RPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAIS 425
            RPGCCA     E Y TS +FPD+TL+FIK+HPLMD AVP I + PWF +T VRYRLT I+
Sbjct: 365  RPGCCAGSSSLERYATSNEFPDDTLNFIKTHPLMDEAVPSIFNRPWFLRTMVRYRLTKIA 424

Query: 426  VDHSAGPYQNYTVIFVGSEAGMVLKVLAK--TSPFSLNDSVLLEEIEAYNHAKCSAENEE 483
            VD +AGPYQN+TV+F+GSE G++LK LA+   S F LNDS+ LEE+  YN  KCS +  E
Sbjct: 425  VDTAAGPYQNHTVVFLGSEKGIILKFLARIGNSGF-LNDSLFLEEMSVYNSEKCSYDGVE 483

Query: 484  DKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQ-GSCG 542
            DK+++ +QLD+   +LYVAFS+C+I++PL RCER+G CKK+CIASRDPYCGW+ + G+C 
Sbjct: 484  DKRIMGMQLDRASSSLYVAFSTCVIKVPLGRCERHGKCKKTCIASRDPYCGWIKEGGACS 543

Query: 543  RVTPGMLAEGYEQDTEFGNTAHLGDCH-----------EILPTSTTPD------YKIFGG 585
             ++P      +EQD E GNT  LGDCH            +LP++TT D      Y+  GG
Sbjct: 544  HLSPNSRLT-FEQDIERGNTDGLGDCHNSFVALNGHSSSLLPSTTTSDSTAQEGYESRGG 602

Query: 586  ----------PTS----------------GVRWEVQSGESNQMVHMNVLITCVFAAFVLG 619
                      P S                GV  E      +Q+V + +L   V  AFV+G
Sbjct: 603  MLDWKHLLDSPDSTDPLGAVSSHNHQDKKGVIRESYLKGHDQLVPVTLLAIAVILAFVMG 662

Query: 620  AFIAGVAVYCYRDMFVRKNRKI--HKDAESAQSCTDSSGSFAKLNGLFDSPVKEYQQNID 677
            A  +G+ VYC  D   RK+  +   K+ E   S   S  S  KL+GLF     + Q    
Sbjct: 663  AVFSGITVYCVCD-HRRKDVAVVQRKEKELTHSRRGSMSSVTKLSGLFG----DTQSKDP 717

Query: 678  SPKLYSNLLTSRKELPPNGDTKSMVMDHRGQPPELAALPTPESTPVLHQKTLQAMKSHSE 737
             P+     L    +L   G+T  M++       +L ALPTPESTP L QK   +  S   
Sbjct: 718  KPEAILTPLMHNGKLATPGNTAKMLIKADQHHLDLTALPTPESTPTLQQKRKPSRGSREW 777

Query: 738  KAHGH--GASRKETPQFFPSSPPPHSPL--SHGHIPSAIVLPNATHDYNTSFSNSNAHKA 793
            + + +   A  K+ P       P   PL  S  HIPS +VLP     Y   +        
Sbjct: 778  ERNQNLINACTKDMPPMGSPVIPTDLPLRASPSHIPSVVVLPITQQGYQHEY-------- 829

Query: 794  EKKLQNIDHPLTKSSSKRDHRRSVDSRNTLNDLLKHLNDPNSNPKAIMGDIQMAHQNLML 853
                  +D P          + S  ++  L D    L       K I   +     N  +
Sbjct: 830  ------VDQP----------KMSEVAQMALEDQAATL-----EYKTIKEHLSSKSPNHGV 868

Query: 854  DPMGSMSEVPPKVPNREASLYSPPSTLPRNSPTKRVDVPTTPGVPMTSLERQRGYHKNSS 913
            + + ++  +PPKVP REASL  P ++L +   +KR+++  +       ++ +R Y  NS 
Sbjct: 869  NLVENLDSLPPKVPQREASLGPPGASLSQTGLSKRLEMHHSSSY---GVDYKRSYPTNSL 925

Query: 914  QR-HSISAMPK-NLNSPNGVLLSRQPSMNRGGYMPTPTGAKVDYIQ-------GTPVSVH 964
             R H  + + + N NS N   LSR  S  RG   P P   +VD IQ       G  V+V 
Sbjct: 926  TRSHQATTLKRNNTNSSNSSHLSRNQSFGRGD-NPPPAPQRVDSIQVHSSQPSGQAVTVS 984

Query: 965  LQPSLSRQSSYTSNGTLPRTGLKRTPSLKPDVPPKPSFVPQTPSVRP 1011
             QPSL+  +S T      R+GLKRTPSLKPDVPPKPSF P + S++P
Sbjct: 985  RQPSLNAYNSLT------RSGLKRTPSLKPDVPPKPSFAPLSTSMKP 1025


>gi|16306552 semaphorin Y [Homo sapiens]
          Length = 930

 Score =  633 bits (1632), Expect = 0.0
 Identities = 351/781 (44%), Positives = 482/781 (61%), Gaps = 51/781 (6%)

Query: 4   FLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRG-RPSGNESQHRLDFQLM 62
           F+    +LLL+       +FP+D  PL   D   +     FRG       ++  LDFQ  
Sbjct: 7   FMPLLLLLLLLSLPHTQAAFPQDPLPLLISDLQGTSPLSWFRGLEDDAVAAELGLDFQRF 66

Query: 63  LKIRDTLYIAGRDQVYTVNLNEMPKTE-VIPNKKLTWRSRQQDRENCAMKGKHKDECHNF 121
           L +  TL +A RD V++ +L    + E ++PNK LTWRS  QD ENCA++GK  DEC+N+
Sbjct: 67  LTLNRTLLVAARDHVFSFDLQAEEEGEGLVPNKYLTWRS--QDVENCAVRGKLTDECYNY 124

Query: 122 IKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFADG 181
           I+V VP + + +  CGTN+F+P+CR Y +++L+ +GEE+SG ARCPFDA Q+NVA+FA+G
Sbjct: 125 IRVLVPWDSQTLLACGTNSFSPVCRSYGITSLQQEGEELSGQARCPFDATQSNVAIFAEG 184

Query: 182 KLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIA 241
            LYSAT ADF ASDAV+YRS+G    LR+ KYDSKW++EPHF+ A+E+G++VYFFFRE++
Sbjct: 185 SLYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVQALEHGDHVYFFFREVS 244

Query: 242 VEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSIT 301
           VE   LG+  +SRVAR+CK DMGGS R L++HWTSFLK RLNCSVPGDS FYFDVLQ++T
Sbjct: 245 VEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTFYFDVLQALT 304

Query: 302 DIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDK 361
             + ++G   + GVFTTQ NSIPGSAVCAF +D+IE+ F+G+FKEQ++ D  WT V ED+
Sbjct: 305 GPVNLHGRSALFGVFTTQTNSIPGSAVCAFYLDEIERGFEGKFKEQRSLDGAWTPVSEDR 364

Query: 362 VPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRL 421
           VP PRPG CA  G A  + +S D PD+ L+FIK+HPL+D AVPP+  +P  T T  R  L
Sbjct: 365 VPSPRPGSCAGVGGAALFSSSRDLPDDVLTFIKAHPLLDPAVPPVTHQPLLTLTS-RALL 423

Query: 422 TAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAEN 481
           T ++VD  AGP+ N TV+F+GS  G VLKVL         + +LLEEI+AY+ A+CS + 
Sbjct: 424 TQVAVDGMAGPHSNITVMFLGSNDGTVLKVLTPGGRSGGPEPILLEEIDAYSPARCSGKR 483

Query: 482 --EEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQG 539
             +  +++I L+LD + H L+VAFS CI+ +PLSRC R+G+C++SC+AS+DPYCGW S  
Sbjct: 484 TAQTARRIIGLELDTEGHRLFVAFSGCIVYLPLSRCARHGACQRSCLASQDPYCGWHSSR 543

Query: 540 SCGRVTPGMLAEGYEQDTEFGNTAHL--GDCHEILPTSTTPDYKIFGGPTSGVRWEVQSG 597
            C  +       G     + GN   +  GDC +      T      G    GVR ++   
Sbjct: 544 GCVDIR----GSGGTDVDQAGNQESMEHGDCQD----GATGSQSGPGDSAYGVRRDLPPA 595

Query: 598 ESNQMVHMNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHKDAESAQSCTD-SSG 656
            +++ V + +L+  V AAF LGA ++G+ V C      R +R+  KD E+       S  
Sbjct: 596 SASRSVPIPLLLASVAAAFALGASVSGLLVSC---ACRRAHRRRGKDIETPGLPRPLSLR 652

Query: 657 SFAKLNGLFDSPVKEYQQN--IDSPKLYSNLLTSRKELPPNGDTKSMVMDHRGQPPELAA 714
           S A+L+G    P    +    + +P+LY+  L      PP G            PPELA 
Sbjct: 653 SLARLHGGGPEPPPPSKDGDAVQTPQLYTTFLP-----PPEG----------VPPPELAC 697

Query: 715 LPTPESTPVLHQKTLQA-------------MKSHSEKAHGHGASRKETPQFFPSSPPPHS 761
           LPTPESTP L  K L+A              K    ++ G  A+    P+     PPP  
Sbjct: 698 LPTPESTPELPVKHLRAAGDPWEWNQNRNNAKEGPGRSRGGHAAGGPAPRVLVRPPPPGC 757

Query: 762 P 762
           P
Sbjct: 758 P 758


>gi|19718780 semaphorin 6B precursor [Homo sapiens]
          Length = 888

 Score =  631 bits (1628), Expect = 0.0
 Identities = 349/799 (43%), Positives = 476/799 (59%), Gaps = 68/799 (8%)

Query: 8   AYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGN----ESQHRLDFQLML 63
           A +LLL++       FPE+  PL+     Y   YPVF G   G     E    L+ Q +L
Sbjct: 12  ALLLLLLLLGGAHGLFPEEPPPLSVAPRDYLNHYPVFVGSGPGRLTPAEGADDLNIQRVL 71

Query: 64  KIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHNFIK 123
           ++  TL+I  RD +Y V L     TE+   +KLTWRS   D   C MKGK + EC NF+K
Sbjct: 72  RVNRTLFIGDRDNLYRVELEPPTSTELRYQRKLTWRSNPSDINVCRMKGKQEGECRNFVK 131

Query: 124 VFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFADGKL 183
           V + R++  +FVCG+NAFNP+C  Y + TL+  G+ ISG+ARCP+D +  NVALF+DG L
Sbjct: 132 VLLLRDESTLFVCGSNAFNPVCANYSIDTLQPVGDNISGMARCPYDPKHANVALFSDGML 191

Query: 184 YSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIAVE 243
           ++ATV DFLA DAVIYRS+GD   LRT+K+DSKW KEP+F+HA+E+G++VYFFFREIA+E
Sbjct: 192 FTATVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWFKEPYFVHAVEWGSHVYFFFREIAME 251

Query: 244 HNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDI 303
            N L K V SRVAR+CKND+GGS RVLEK WTSFLKARLNCSVPGDS FYF+VLQ++T +
Sbjct: 252 FNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSHFYFNVLQAVTGV 311

Query: 304 IQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVP 363
           + + G P V+ VF+T  NSIPGSAVCAF +  +  VF+GRF+EQK+P+S+WT VPED+VP
Sbjct: 312 VSLGGRPVVLAVFSTPSNSIPGSAVCAFDLTQVAAVFEGRFREQKSPESIWTPVPEDQVP 371

Query: 364 KPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTA 423
           +PRPGCCA  G+   Y  S   PD+ L+F+K+HPLMD AVP +   PW  +T +R++LT 
Sbjct: 372 RPRPGCCAAPGM--QYNASSALPDDILNFVKTHPLMDEAVPSLGHAPWILRTLMRHQLTR 429

Query: 424 ISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLND---SVLLEEIEAYNHAKCS-- 478
           ++VD  AGP+ N TV+F+GSEAG VLK L + +  +      SV LEE E Y   +C   
Sbjct: 430 VAVDVGAGPWGNQTVVFLGSEAGTVLKFLVRPNASTSGTSGLSVFLEEFETYRPDRCGRP 489

Query: 479 AENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQ 538
              E  ++++SL+LD     L  AF  C++R+P++RC++Y  C K+CI S+DPYCGW   
Sbjct: 490 GGGETGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQQYSGCMKNCIGSQDPYCGWAPD 549

Query: 539 GSCGRVTPGMLAEGYEQDTEFGNTAHLGDCHEILPTSTTPDYKIFGGPTSGVRWEVQSGE 598
           GSC  ++PG  A  +EQD    +T+ LGDC  +L  S + D               ++G 
Sbjct: 550 GSCIFLSPGTRA-AFEQDVSGASTSGLGDCTGLLRASLSED---------------RAG- 592

Query: 599 SNQMVHMNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHKDAES--AQSCTDSSG 656
              +V +N+L+T   AAFV+GA ++G +V  +  +  R+     KD E+  A    ++  
Sbjct: 593 ---LVSVNLLVTSSVAAFVVGAVVSGFSVGWFVGLRERRELARRKDKEAILAHGAGEAVL 649

Query: 657 SFAKLNGLFDSPVKEYQQNIDSPKLYSNLLTSRKELPP---------NGDTKSMVMDHRG 707
           S ++L           ++    P            +PP         NG  K+ ++    
Sbjct: 650 SVSRLG----------ERRAQGPGGRGGGGGGGAGVPPEALLAPLMQNGWAKATLLQGGP 699

Query: 708 QPPELAALPTPESTPVLHQKTLQAMKSHSEKA------HGH---GASRKET-----PQFF 753
              +   LPTPE TP L QK L     H          HGH    AS   +     P   
Sbjct: 700 HDLDSGLLPTPEQTP-LPQKRLPTPHPHPHALGPRAWDHGHPLLPASASSSLLLLAPARA 758

Query: 754 PSSPP-PHSPLSHGHIPSA 771
           P  PP P  P   G + +A
Sbjct: 759 PEQPPAPGEPTPDGRLYAA 777


>gi|41406086 semaphorin 3D [Homo sapiens]
          Length = 777

 Score =  313 bits (802), Expect = 5e-85
 Identities = 190/556 (34%), Positives = 286/556 (51%), Gaps = 40/556 (7%)

Query: 53  SQHRLDFQLML--KIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAM 110
           S   LDFQ +L  + R  L +  +D ++ ++L ++ K      KK+ W + ++  E C +
Sbjct: 64  SSEGLDFQTLLLDEERGRLLLGAKDHIFLLSLVDLNKNF----KKIYWPAAKERVELCKL 119

Query: 111 KGKHKD-ECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYD-------GEEISG 162
            GK  + EC NFI+V  P N   ++VCGT AF+P+C Y  L   + D           SG
Sbjct: 120 AGKDANTECANFIRVLQPYNKTHIYVCGTGAFHPICGYIDLGVYKEDIIFKLDTHNLESG 179

Query: 163 LARCPFDARQTNVALFADGKLYSATVADFLASDAVIYRSMG---DGSALRTIKYDSKWIK 219
             +CPFD +Q   ++  D  LYS T +DFL  D    RS+G   D   +RT   +  W+ 
Sbjct: 180 RLKCPFDPQQPFASVMTDEYLYSGTASDFLGKDTAFTRSLGPTHDHHYIRTDISEHYWLN 239

Query: 220 EPHFLHAIEY-------GNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEK 272
              F+             + +YFFFRE + E +   K + SRV R+CKND+GG + ++ K
Sbjct: 240 GAKFIGTFFIPDTYNPDDDKIYFFFRESSQEGSTSDKTILSRVGRVCKNDVGGQRSLINK 299

Query: 273 HWTSFLKARLNCSVPGD--SFFYFDVLQSITDI-IQINGIPTVVGVFTTQLNSIPGSAVC 329
            WT+FLKARL CS+PG   +  YFD LQ I  +  +    P V GVFTT  +   GSAVC
Sbjct: 300 -WTTFLKARLICSIPGSDGADTYFDELQDIYLLPTRDERNPVVYGVFTTTSSIFKGSAVC 358

Query: 330 AFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDET 389
            +SM DI  VF G +  +++ D  W    + ++P PRPG C         K++ DFPD+ 
Sbjct: 359 VYSMADIRAVFNGPYAHKESADHRWVQY-DGRIPYPRPGTCPSKTYDPLIKSTRDFPDDV 417

Query: 390 LSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVL 449
           +SFIK H +M  +V P+A  P F +  V YRLT I VDH       Y V+F+G++ G VL
Sbjct: 418 ISFIKRHSVMYKSVYPVAGGPTFKRINVDYRLTQIVVDHVIAEDGQYDVMFLGTDIGTVL 477

Query: 450 KVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIR 509
           KV++ +      + V+LEE++ + H+           +++++L      LY+     +++
Sbjct: 478 KVVSISKEKWNMEEVVLEELQIFKHSSI---------ILNMELSLKQQQLYIGSRDGLVQ 528

Query: 510 IPLSRCERYGSCKKSCIASRDPYCGWLSQGSCGRVTPGMLAEGYEQDTEFGN-TAHLGDC 568
           + L RC+ YG     C  +RDPYC W    +C R  P        QD ++G+      D 
Sbjct: 529 LSLHRCDTYGKACADCCLARDPYCAW-DGNACSRYAPTSKRRARRQDVKYGDPITQCWDI 587

Query: 569 HEILPTSTTPDYKIFG 584
            + +   T  +  IFG
Sbjct: 588 EDSISHETADEKVIFG 603


>gi|91982767 semaphorin 5B isoform 1 [Homo sapiens]
          Length = 1151

 Score =  308 bits (790), Expect = 1e-83
 Identities = 191/525 (36%), Positives = 297/525 (56%), Gaps = 47/525 (8%)

Query: 12  LLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQLMLKIRDTLYI 71
           L  +S+   V+F +    ++   Y  +R +      PSGN        QL++  R+ L+ 
Sbjct: 97  LCALSKHPTVAFEDLQPWVSNFTYPGARDFSQLALDPSGN--------QLIVGARNYLF- 147

Query: 72  AGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHNFIKVFVPRNDE 131
               ++   N++ +  TE        W S +  R +C  KGK ++EC N+++V +    +
Sbjct: 148 ----RLSLANVSLLQATE--------WASSEDTRRSCQSKGKTEEECQNYVRVLIVAGRK 195

Query: 132 MVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFAD-GKLYSATVAD 190
            VF+CGTNAF+PMC   ++  L    E+I+G+ARCP+D R  + A+ +  G+LY+ATV D
Sbjct: 196 -VFMCGTNAFSPMCTSRQVGNLSRTIEKINGVARCPYDPRHNSTAVISSQGELYAATVID 254

Query: 191 FLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIAVEHNNLGKA 250
           F   D  IYRS+G G  LRT +Y+SKW+ EP+F+ A + G + YFF RE AVEH + G+ 
Sbjct: 255 FSGRDPAIYRSLGSGPPLRTAQYNSKWLNEPNFVAAYDIGLFAYFFLRENAVEH-DCGRT 313

Query: 251 VYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDIIQINGIP 310
           VYSRVAR+CKND+GG + +LE  WT+F+KARLNCS PG+  FY++ LQS   + + +   
Sbjct: 314 VYSRVARVCKNDVGG-RFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSAFHLPEQD--- 369

Query: 311 TVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCC 370
            + GVFTT +NSI  SAVCAF++  I + F G F+ Q+ P + W  +  + +P  + G  
Sbjct: 370 LIYGVFTTNVNSIAASAVCAFNLSAISQAFNGPFRYQENPRAAWLPI-ANPIPNFQCGTL 428

Query: 371 AKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAISVDHSA 430
            + G  E      +  + +L   +   LM  AV P+  EP  T+  VR+  + + VD   
Sbjct: 429 PETGPNE------NLTERSLQDAQRLFLMSEAVQPVTPEPCVTQDSVRF--SHLVVDLVQ 480

Query: 431 GPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISL 490
                Y V+++G+E+G +LK L+ T+  SL+    LEE+      +        + + SL
Sbjct: 481 AKDTLYHVLYIGTESGTILKALS-TASRSLH-GCYLEELHVLPPGR-------REPLRSL 531

Query: 491 QLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGW 535
           ++     AL+V     ++R+PL RC  Y S + +C+ +RDPYCGW
Sbjct: 532 RILHSARALFVGLRDGVLRVPLERCAAYRS-QGACLGARDPYCGW 575


>gi|5174673 semaphorin 3A precursor [Homo sapiens]
          Length = 771

 Score =  305 bits (781), Expect = 1e-82
 Identities = 187/545 (34%), Positives = 282/545 (51%), Gaps = 48/545 (8%)

Query: 66  RDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKH-KDECHNFIKV 124
           R  LY+  +D +++ +L       +   +K+ W      R+ C   GK    EC NFIKV
Sbjct: 66  RSRLYVGAKDHIFSFDL-----VNIKDFQKIVWPVSYTRRDECKWAGKDILKECANFIKV 120

Query: 125 FVPRNDEMVFVCGTNAFNPMCRYYRLS--------TLEYDGEEISGLARCPFDARQTNVA 176
               N   ++ CGT AF+P+C Y  +          LE    E +G  + P+D +    +
Sbjct: 121 LKAYNQTHLYACGTGAFHPICTYIEIGHHPEDNIFKLENSHFE-NGRGKSPYDPKLLTAS 179

Query: 177 LFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFL--HAIEYG---- 230
           L  DG+LYS T ADF+  D  I+R++G    +RT ++DS+W+ +P F+  H I       
Sbjct: 180 LLIDGELYSGTAADFMGRDFAIFRTLGHHHPIRTEQHDSRWLNDPKFISAHLISESDNPE 239

Query: 231 -NYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGD 289
            + VYFFFRE A++  + GKA ++R+ +ICKND GG + ++ K WT+FLKARL CSVPG 
Sbjct: 240 DDKVYFFFRENAIDGEHSGKATHARIGQICKNDFGGHRSLVNK-WTTFLKARLICSVPGP 298

Query: 290 SFF--YFDVLQSITDIIQIN----GIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGR 343
           +    +FD LQ   D+  +N      P V GVFTT  N   GSAVC +SM D+ +VF G 
Sbjct: 299 NGIDTHFDELQ---DVFLMNFKDPKNPVVYGVFTTSSNIFKGSAVCMYSMSDVRRVFLGP 355

Query: 344 FKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAV 403
           +  +  P+  W    + +VP PRPG C        + ++ D PD+ ++F +SHP M + V
Sbjct: 356 YAHRDGPNYQWVPY-QGRVPYPRPGTCPSKTFG-GFDSTKDLPDDVITFARSHPAMYNPV 413

Query: 404 PPIADEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLA--KTSPFSLN 461
            P+ + P   KT V Y+ T I VD        Y V+F+G++ G VLKV++  K + + L 
Sbjct: 414 FPMNNRPIVIKTDVNYQFTQIVVDRVDAEDGQYDVMFIGTDVGTVLKVVSIPKETWYDL- 472

Query: 462 DSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSC 521
           + VLLEE+  +          E   + +++L      LY+  ++ + ++PL RC+ YG  
Sbjct: 473 EEVLLEEMTVF---------REPTAISAMELSTKQQQLYIGSTAGVAQLPLHRCDIYGKA 523

Query: 522 KKSCIASRDPYCGWLSQGSCGRVTPGMLAEGYEQDTEFGN-TAHLGDCHEILPTSTTPDY 580
              C  +RDPYC W    +C R  P        QD   G+   H  D H       +P+ 
Sbjct: 524 CAECCLARDPYCAW-DGSACSRYFPTAKRRTRRQDIRNGDPLTHCSDLHHDNHHGHSPEE 582

Query: 581 KIFGG 585
           +I  G
Sbjct: 583 RIIYG 587


>gi|6912650 semaphorin 3E [Homo sapiens]
          Length = 775

 Score =  298 bits (764), Expect = 1e-80
 Identities = 184/531 (34%), Positives = 275/531 (51%), Gaps = 41/531 (7%)

Query: 57  LDFQLML--KIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKH 114
           LD   ML  + ++ L++ GRD VY+++L  +        K++ W S     E C MKGK 
Sbjct: 56  LDLHTMLLDEYQERLFVGGRDLVYSLSLERISDGY----KEIHWPSTALKMEECIMKGKD 111

Query: 115 KDECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYR--------LSTLEYDGEEISGLARC 166
             EC N+++V    N   +  CGT AF+P+C + R        L  LE    E  G  RC
Sbjct: 112 AGECANYVRVLHHYNRTHLLTCGTGAFDPVCAFIRVGYHLEDPLFHLESPRSE-RGRGRC 170

Query: 167 PFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHA 226
           PFD   + ++     +L++   +D+ + DA I+RSMG  + +RT   D + +KEP F+ +
Sbjct: 171 PFDPSSSFISTLIGSELFAGLYSDYWSRDAAIFRSMGRLAHIRTEHDDERLLKEPKFVGS 230

Query: 227 IEY-------GNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLK 279
                      N VYFFF E A+E  N   A+Y+RV R+C ND+GG QR+L   W++FLK
Sbjct: 231 YMIPDNEDRDDNKVYFFFTEKALEAENNAHAIYTRVGRLCVNDVGG-QRILVNKWSTFLK 289

Query: 280 ARLNCSVPGDSFF--YFDVLQSITDI-IQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDI 336
           ARL CSVPG +    YFD L+ +  +  + +  P + G+F T  N   G A+C + M  I
Sbjct: 290 ARLVCSVPGMNGIDTYFDELEDVFLLPTRDHKNPVIFGLFNTTSNIFRGHAICVYHMSSI 349

Query: 337 EKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSH 396
              F G +  ++ P+  W+ V E KVP PRPG CA       Y T+ D+PD+ + F +SH
Sbjct: 350 RAAFNGPYAHKEGPEYHWS-VYEGKVPYPRPGSCASKVNGGRYGTTKDYPDDAIRFARSH 408

Query: 397 PLMDSAVPPIADEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLA-KT 455
           PLM  A+ P   +P   KT  +Y L  I+VD        Y V+F+G++ G+VLKV+    
Sbjct: 409 PLMYQAIKPAHKKPILVKTDGKYNLKQIAVDRVEAEDGQYDVLFIGTDNGIVLKVITIYN 468

Query: 456 SPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRC 515
                 + V+LEE++ +         ++   +IS+++      LY+  +S + ++    C
Sbjct: 469 QEMESMEEVILEELQIF---------KDPVPIISMEISSKRQQLYIGSASAVAQVRFHHC 519

Query: 516 ERYGSCKKSCIASRDPYCGWLSQGSCGRVTP-GMLAEG--YEQDTEFGNTA 563
           + YGS    C  +RDPYC W    SC R  P G  A+     QD   GN A
Sbjct: 520 DMYGSACADCCLARDPYCAW-DGISCSRYYPTGTHAKRRFRRQDVRHGNAA 569


>gi|147904700 semaphorin 5A [Homo sapiens]
          Length = 1074

 Score =  295 bits (755), Expect = 1e-79
 Identities = 172/469 (36%), Positives = 260/469 (55%), Gaps = 34/469 (7%)

Query: 69  LYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHNFIKVFVPR 128
           L +  R+ ++ + L ++   + +      W   +  ++ C  KGK K+EC N+I+V +  
Sbjct: 70  LVVGARNYLFRLQLEDLSLIQAVE-----WECDEATKKACYSKGKSKEECQNYIRVLLVG 124

Query: 129 NDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALF-ADGKLYSAT 187
            D + F CGTNAF P+C    LS L    ++ISG+ARCP+  +  + AL  A G+LY+AT
Sbjct: 125 GDRL-FTCGTNAFTPVCTNRSLSNLTEIHDQISGMARCPYSPQHNSTALLTAGGELYAAT 183

Query: 188 VADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIAVEHNNL 247
             DF   D  IYRS+G    LRT +Y+SKW+ EP+F+ + + GN+ YFFFRE AVEH + 
Sbjct: 184 AMDFPGRDPAIYRSLGILPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVEH-DC 242

Query: 248 GKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDIIQIN 307
           GK V+SR AR+CKND+GG + +LE  WT+F+KARLNCS PG+  FY++ LQS   + +++
Sbjct: 243 GKTVFSRAARVCKNDIGG-RFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSTFFLPELD 301

Query: 308 GIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRP 367
               + G+FTT +NSI  SAVC F++  I + F G FK Q+   S W   P    P P  
Sbjct: 302 ---LIYGIFTTNVNSIAASAVCVFNLSAIAQAFSGPFKYQENSRSAWLPYPN---PNPHF 355

Query: 368 GC-CAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAISV 426
            C     GL       ++  +  L   +   LM   V P+   P F +   R+  + ++V
Sbjct: 356 QCGTVDQGL------YVNLTERNLQDAQKFILMHEVVQPVTTVPSFMEDNSRF--SHVAV 407

Query: 427 DHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKK 486
           D   G      +I++ ++ G + KV    +  S   S LLEEIE +            + 
Sbjct: 408 DVVQGREALVHIIYLATDYGTIKKVRVPLNQTS--SSCLLEEIELF-------PERRREP 458

Query: 487 VISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGW 535
           + SLQ+      L+V     +++IPL RC+ Y + + +CI ++DPYCGW
Sbjct: 459 IRSLQILHSQSVLFVGLREHVVKIPLKRCQFYRT-RSTCIGAQDPYCGW 506


>gi|188497703 semaphorin 3F [Homo sapiens]
          Length = 785

 Score =  294 bits (752), Expect = 3e-79
 Identities = 180/557 (32%), Positives = 282/557 (50%), Gaps = 72/557 (12%)

Query: 58  DFQLMLKIRD--TLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHK 115
           D++++LK  D   +Y+  +D V +++L+++ +  +I    + W +  Q  E C + GK  
Sbjct: 56  DYRILLKDEDHDRMYVGSKDYVLSLDLHDINREPLI----IHWAASPQRIEECVLSGKDV 111

Query: 116 D-ECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYR------------------------- 149
           + EC NF+++  P N   ++VCGT A+NPMC Y                           
Sbjct: 112 NGECGNFVRLIQPWNRTHLYVCGTGAYNPMCTYVNRGRRAQATPWTQTQAVRGRGSRATD 171

Query: 150 --------------LSTLEYDGEEISGLARCPFDARQTNVALFADGKLYSATVADFLASD 195
                         +  LE +  E SG  +CP+D +    +   + +LY+    DF+ +D
Sbjct: 172 GALRPMPTAPRQDYIFYLEPERLE-SGKGKCPYDPKLDTASALINEELYAGVYIDFMGTD 230

Query: 196 AVIYRSMGDGSALRTIKYDSKWIKEPHFLHAI-------EYGNYVYFFFREIAVEHNNLG 248
           A I+R++G  +A+RT +Y+S+W+ +P F+HA           + +YFFFRE + E     
Sbjct: 231 AAIFRTLGKQTAMRTDQYNSRWLNDPSFIHAELIPDSAERNDDKLYFFFRERSAEAPQ-S 289

Query: 249 KAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFF--YFDVLQSITDIIQI 306
            AVY+R+ RIC ND GG   ++ K W++FLKARL CSVPG+     +FD LQ +  + Q 
Sbjct: 290 PAVYARIGRICLNDDGGHCCLVNK-WSTFLKARLVCSVPGEDGIETHFDELQDVF-VQQT 347

Query: 307 NGI--PTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPK 364
             +  P +  VFT+  +   GSAVC +SM DI  VF G F  ++ P+  W      K+P 
Sbjct: 348 QDVRNPVIYAVFTSSGSVFRGSAVCVYSMADIRMVFNGPFAHKEGPNYQWMPF-SGKMPY 406

Query: 365 PRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAI 424
           PRPG C       + K++ D+PDE ++F++SHPLM  AV P+   P   +T   YRLT I
Sbjct: 407 PRPGTCPGGTFTPSMKSTKDYPDEVINFMRSHPLMYQAVYPLQRRPLVVRTGAPYRLTTI 466

Query: 425 SVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEED 484
           +VD        Y V+F+G++ G V KV+         + ++LEE+E +         ++ 
Sbjct: 467 AVDQVDAADGRYEVLFLGTDRGTVQKVIVLPKDDQELEELMLEEVEVF---------KDP 517

Query: 485 KKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGSCGRV 544
             V ++ +      LYVA +  +  + L RC+ YG+    C  +RDPYC W  Q +C R 
Sbjct: 518 APVKTMTISSKRQQLYVASAVGVTHLSLHRCQAYGAACADCCLARDPYCAWDGQ-ACSRY 576

Query: 545 TPGMLAEGYEQDTEFGN 561
           T         QD   GN
Sbjct: 577 TASSKRRSRRQDVRHGN 593


>gi|4759092 semaphorin 3B isoform 1 precursor [Homo sapiens]
          Length = 749

 Score =  289 bits (739), Expect = 1e-77
 Identities = 185/539 (34%), Positives = 273/539 (50%), Gaps = 40/539 (7%)

Query: 66  RDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKH-KDECHNFIKV 124
           R  L++   + V ++NL+ + K      KKL W +  + RE C   GK    EC NF+K+
Sbjct: 64  RGRLFVGAENHVASLNLDNISKRA----KKLAWPAPVEWREECNWAGKDIGTECMNFVKL 119

Query: 125 FVPRNDEMVFVCGTNAFNPMCRYYRLS------TLEYDGEEIS-GLARCPFDARQTNVAL 177
               N   +  CGT AF+P C +  +        L  D   I  G  + P+D R    ++
Sbjct: 120 LHAYNRTHLLACGTGAFHPTCAFVEVGHRAEEPVLRLDPGRIEDGKGKSPYDPRHRAASV 179

Query: 178 FADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEY-------G 230
               +LYS   AD +  D  I+RS+G   +LRT  +DS+W+ EP F+             
Sbjct: 180 LVGEELYSGVAADLMGRDFTIFRSLGQRPSLRTEPHDSRWLNEPKFVKVFWIPESENPDD 239

Query: 231 NYVYFFFREIAVEHNN-LGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPG- 288
           + +YFFFRE AVE    LG+   SRV +IC+ND+GG QR L   WT+FLKARL CSVPG 
Sbjct: 240 DKIYFFFRETAVEAAPALGRLSVSRVGQICRNDVGG-QRSLVNKWTTFLKARLVCSVPGV 298

Query: 289 DSFFYFDVLQSITDII-QINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQ 347
           +   +FD LQ +  +  + +  P +  VF+T  +   GSAVC +SM+D+ + F G F  +
Sbjct: 299 EGDTHFDQLQDVFLLSSRDHRTPLLYAVFSTSSSIFQGSAVCVYSMNDVRRAFLGPFAHK 358

Query: 348 KTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIA 407
           + P   W +  + +VP PRPG C        + ++ DFPD+ + F ++HPLM ++V P  
Sbjct: 359 EGPMHQWVSY-QGRVPYPRPGMCPSKTFG-TFSSTKDFPDDVIQFARNHPLMYNSVLPTG 416

Query: 408 DEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLA--KTSPFSLNDSVL 465
             P F +    Y  T I+ D  A    +Y V+F+G++ G VLKV++  K S  S  + +L
Sbjct: 417 GRPLFLQVGANYTFTQIAADRVAAADGHYDVLFIGTDVGTVLKVISVPKGSRPSA-EGLL 475

Query: 466 LEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSC 525
           LEE+  +         E+   V S+Q+    H LYVA  S + +I L RC  +G     C
Sbjct: 476 LEELHVF---------EDSAAVTSMQISSKRHQLYVASRSAVAQIALHRCAAHGRVCTEC 526

Query: 526 IASRDPYCGWLSQGSCGRVTPGMLAEGYEQDTEFGNTAHLGDCHEILPTSTTPDYKIFG 584
             +RDPYC W    +C R  P        QD   G+ + L  C          ++K+FG
Sbjct: 527 CLARDPYCAW-DGVACTRFQPSAKRRFRRQDVRNGDPSTL--CSGDSSRPALLEHKVFG 582


>gi|5454048 semaphorin 3C [Homo sapiens]
          Length = 751

 Score =  288 bits (738), Expect = 1e-77
 Identities = 171/529 (32%), Positives = 280/529 (52%), Gaps = 37/529 (6%)

Query: 53  SQHRLDFQLML--KIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAM 110
           S H LD++++L  + +D +Y+  +D + ++N+N + +  +     + W +     E C M
Sbjct: 48  SHHPLDYRILLMDEDQDRIYVGSKDHILSLNINNISQEAL----SVFWPASTIKVEECKM 103

Query: 111 KGKHKDE-CHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLS------TLEYDGEEISGL 163
            GK     C NF++V    N   ++VCG+ AF+P+C Y              D +  SG 
Sbjct: 104 AGKDPTHGCGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGK 163

Query: 164 ARCPFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHF 223
            RC F+     V++  + +L+S    DF+ +DA I+RS+   +A+RT +++SKW+ EP F
Sbjct: 164 GRCSFNPNVNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMF 223

Query: 224 L--HAIEYGN-----YVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTS 276
           +  H I  G       VYFFF+E   ++N   K ++S +ARIC ND GG + ++ K WT+
Sbjct: 224 VDAHVIPDGTDPNDAKVYFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSLVNK-WTT 282

Query: 277 FLKARLNCSVPGDSF--FYFDVLQSITDIIQINGIPTVV-GVFTTQLNSIPGSAVCAFSM 333
           FLKARL CSV  +     +FD L+ +  +   N   T+V G+FTT  +   GSAVC + +
Sbjct: 283 FLKARLVCSVTDEDGPETHFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHL 342

Query: 334 DDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFI 393
            DI+ VF G F  ++ P+    +  + ++P PRPG C         +T+ +FPD+ ++FI
Sbjct: 343 SDIQTVFNGPFAHKEGPNHQLISY-QGRIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFI 401

Query: 394 KSHPLMDSAVPPIADEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLA 453
           ++HPLM +++ PI   P   +    Y+ T I+VD        Y V+F+G++ G V KV+ 
Sbjct: 402 RNHPLMYNSIYPIHKRPLIVRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVV 461

Query: 454 KTSPFSLNDSVLLEEIEAY-NHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPL 512
             +  S++  ++LEE+E + NHA           + ++++      LYV+ +  + ++ L
Sbjct: 462 LPTNNSVSGELILEELEVFKNHA----------PITTMKISSKKQQLYVSSNEGVSQVSL 511

Query: 513 SRCERYGSCKKSCIASRDPYCGWLSQGSCGRVTPGMLAEGYEQDTEFGN 561
            RC  YG+    C  +RDPYC W    SC R  P        QD   GN
Sbjct: 512 HRCHIYGTACADCCLARDPYCAW-DGHSCSRFYPTGKRRSRRQDVRHGN 559


>gi|54607089 semaphorin 3B isoform 2 precursor [Homo sapiens]
          Length = 748

 Score =  285 bits (729), Expect = 2e-76
 Identities = 185/539 (34%), Positives = 273/539 (50%), Gaps = 41/539 (7%)

Query: 66  RDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKH-KDECHNFIKV 124
           R  L++   + V ++NL+ + K      KKL W +  + RE C   GK    EC NF+K+
Sbjct: 64  RGRLFVGAENHVASLNLDNISKRA----KKLAWPAPVEWREECNWAGKDIGTECMNFVKL 119

Query: 125 FVPRNDEMVFVCGTNAFNPMCRYYRLS------TLEYDGEEIS-GLARCPFDARQTNVAL 177
               N   +  CGT AF+P C +  +        L  D   I  G  + P+D R    ++
Sbjct: 120 LHAYNRTHLLACGTGAFHPTCAFVEVGHRAEEPVLRLDPGRIEDGKGKSPYDPRHRAASV 179

Query: 178 FADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEY-------G 230
               +LYS   AD +  D  I+RS+G   +LRT  +DS+W+ EP F+             
Sbjct: 180 LVGEELYSGVAADLMGRDFTIFRSLGQRPSLRTEPHDSRWLNEPKFVKVFWIPESENPDD 239

Query: 231 NYVYFFFREIAVEHNN-LGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPG- 288
           + +YFFFRE AVE    LG+   SRV +IC+ND+GG QR L   WT+FLKARL CSVPG 
Sbjct: 240 DKIYFFFRETAVEAAPALGRLSVSRVGQICRNDVGG-QRSLVNKWTTFLKARLVCSVPGV 298

Query: 289 DSFFYFDVLQSITDII-QINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQ 347
           +   +FD LQ +  +  + +  P +  VF+T  +   GSAVC +SM+D+ + F G F  +
Sbjct: 299 EGDTHFDQLQDVFLLSSRDHRTPLLYAVFSTS-SIFQGSAVCVYSMNDVRRAFLGPFAHK 357

Query: 348 KTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIA 407
           + P   W +  + +VP PRPG C        + ++ DFPD+ + F ++HPLM ++V P  
Sbjct: 358 EGPMHQWVSY-QGRVPYPRPGMCPSKTFG-TFSSTKDFPDDVIQFARNHPLMYNSVLPTG 415

Query: 408 DEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLA--KTSPFSLNDSVL 465
             P F +    Y  T I+ D  A    +Y V+F+G++ G VLKV++  K S  S  + +L
Sbjct: 416 GRPLFLQVGANYTFTQIAADRVAAADGHYDVLFIGTDVGTVLKVISVPKGSRPSA-EGLL 474

Query: 466 LEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSC 525
           LEE+  +         E+   V S+Q+    H LYVA  S + +I L RC  +G     C
Sbjct: 475 LEELHVF---------EDSAAVTSMQISSKRHQLYVASRSAVAQIALHRCAAHGRVCTEC 525

Query: 526 IASRDPYCGWLSQGSCGRVTPGMLAEGYEQDTEFGNTAHLGDCHEILPTSTTPDYKIFG 584
             +RDPYC W    +C R  P        QD   G+ + L  C          ++K+FG
Sbjct: 526 CLARDPYCAW-DGVACTRFQPSAKRRFRRQDVRNGDPSTL--CSGDSSRPALLEHKVFG 581


>gi|214010220 semaphorin 4D isoform 2 [Homo sapiens]
          Length = 738

 Score =  281 bits (718), Expect = 3e-75
 Identities = 177/494 (35%), Positives = 275/494 (55%), Gaps = 44/494 (8%)

Query: 61  LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKD-ECH 119
           L+ + +DTLYI  R+ V+ VN   + + +     ++ W+  +  +  CA KGK K  EC 
Sbjct: 54  LLSEDKDTLYIGAREAVFAVNALNISEKQ----HEVYWKVSEDKKAKCAEKGKSKQTECL 109

Query: 120 NFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFA 179
           N+I+V  P +   ++VCGTNAF P C +  L++ ++ G+   G  RCPFD   +  ++  
Sbjct: 110 NYIRVLQPLSATSLYVCGTNAFQPACDHLNLTSFKFLGKNEDGKGRCPFDPAHSYTSVMV 169

Query: 180 DGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEY---------- 229
           DG+LYS T  +FL S+ +I R+    S LRT +Y   W+ EP F+ A             
Sbjct: 170 DGELYSGTSYNFLGSEPIISRN-SSHSPLRT-EYAIPWLNEPSFVFADVIRKSPDSPDGE 227

Query: 230 GNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGD 289
            + VYFFF E++VE+  + + +  R+AR+CK D GG  R L+K WTSFLKARL CS P D
Sbjct: 228 DDRVYFFFTEVSVEYEFVFRVLIPRIARVCKGDQGG-LRTLQKKWTSFLKARLICSRP-D 285

Query: 290 SFFYFDVLQSITDIIQING--IPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFK-GRFKE 346
           S   F+VL+ +  +++  G  +P    +FT QLN++  SAVCA+++   E+VF  G++ +
Sbjct: 286 SGLVFNVLRDVF-VLRSPGLKVPVFYALFTPQLNNVGLSAVCAYNLSTAEEVFSHGKYMQ 344

Query: 347 QKTPDSVWT--AVPEDKVPKPRPGCCA-KHGLAEAYKTSIDFPDETLSFIKSHPLMDSAV 403
             T +   T        VPKPRPG C      A  Y +S++ PD+TL F+K HPLMD +V
Sbjct: 345 STTVEQSHTKWVRYNGPVPKPRPGACIDSEARAANYTSSLNLPDKTLQFVKDHPLMDDSV 404

Query: 404 PPIADEPWFTKTRVRYRLTAISVDHS-AGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLND 462
            PI + P   K  V Y  T I VD + A     Y V+FV ++ G + K +      SL  
Sbjct: 405 TPIDNRPRLIKKDVNY--TQIVVDRTQALDGTVYDVMFVSTDRGALHKAI------SLEH 456

Query: 463 SV-LLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSC 521
           +V ++EE + +       ++ E  + + L   K +  +Y   +S +++ PL+ C ++G+C
Sbjct: 457 AVHIIEETQLF-------QDFEPVQTLLLSSKKGNRFVYAGSNSGVVQAPLAFCGKHGTC 509

Query: 522 KKSCIASRDPYCGW 535
            + C+ +RDPYC W
Sbjct: 510 -EDCVLARDPYCAW 522


>gi|214010218 semaphorin 4D isoform 1 [Homo sapiens]
          Length = 862

 Score =  281 bits (718), Expect = 3e-75
 Identities = 177/494 (35%), Positives = 275/494 (55%), Gaps = 44/494 (8%)

Query: 61  LMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKD-ECH 119
           L+ + +DTLYI  R+ V+ VN   + + +     ++ W+  +  +  CA KGK K  EC 
Sbjct: 54  LLSEDKDTLYIGAREAVFAVNALNISEKQ----HEVYWKVSEDKKAKCAEKGKSKQTECL 109

Query: 120 NFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFA 179
           N+I+V  P +   ++VCGTNAF P C +  L++ ++ G+   G  RCPFD   +  ++  
Sbjct: 110 NYIRVLQPLSATSLYVCGTNAFQPACDHLNLTSFKFLGKNEDGKGRCPFDPAHSYTSVMV 169

Query: 180 DGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEY---------- 229
           DG+LYS T  +FL S+ +I R+    S LRT +Y   W+ EP F+ A             
Sbjct: 170 DGELYSGTSYNFLGSEPIISRN-SSHSPLRT-EYAIPWLNEPSFVFADVIRKSPDSPDGE 227

Query: 230 GNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGD 289
            + VYFFF E++VE+  + + +  R+AR+CK D GG  R L+K WTSFLKARL CS P D
Sbjct: 228 DDRVYFFFTEVSVEYEFVFRVLIPRIARVCKGDQGG-LRTLQKKWTSFLKARLICSRP-D 285

Query: 290 SFFYFDVLQSITDIIQING--IPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFK-GRFKE 346
           S   F+VL+ +  +++  G  +P    +FT QLN++  SAVCA+++   E+VF  G++ +
Sbjct: 286 SGLVFNVLRDVF-VLRSPGLKVPVFYALFTPQLNNVGLSAVCAYNLSTAEEVFSHGKYMQ 344

Query: 347 QKTPDSVWT--AVPEDKVPKPRPGCCA-KHGLAEAYKTSIDFPDETLSFIKSHPLMDSAV 403
             T +   T        VPKPRPG C      A  Y +S++ PD+TL F+K HPLMD +V
Sbjct: 345 STTVEQSHTKWVRYNGPVPKPRPGACIDSEARAANYTSSLNLPDKTLQFVKDHPLMDDSV 404

Query: 404 PPIADEPWFTKTRVRYRLTAISVDHS-AGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLND 462
            PI + P   K  V Y  T I VD + A     Y V+FV ++ G + K +      SL  
Sbjct: 405 TPIDNRPRLIKKDVNY--TQIVVDRTQALDGTVYDVMFVSTDRGALHKAI------SLEH 456

Query: 463 SV-LLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSC 521
           +V ++EE + +       ++ E  + + L   K +  +Y   +S +++ PL+ C ++G+C
Sbjct: 457 AVHIIEETQLF-------QDFEPVQTLLLSSKKGNRFVYAGSNSGVVQAPLAFCGKHGTC 509

Query: 522 KKSCIASRDPYCGW 535
            + C+ +RDPYC W
Sbjct: 510 -EDCVLARDPYCAW 522


>gi|157388902 semaphorin 4C [Homo sapiens]
          Length = 833

 Score =  268 bits (685), Expect = 2e-71
 Identities = 166/487 (34%), Positives = 259/487 (53%), Gaps = 52/487 (10%)

Query: 69  LYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKD-ECHNFIKVFVP 127
           LY+  R+ ++  ++  +     I     +W +  + +  C  KGK+   EC NFI+   P
Sbjct: 65  LYVGAREALFAFSMEALELQGAI-----SWEAPVEKKTECIQKGKNNQTECFNFIRFLQP 119

Query: 128 RNDEMVFVCGTNAFNPMCRYYRLSTLEYD-GEEISGLARCPFDARQTNVALFADGKLYSA 186
            N   ++VCGT AF P C Y  + T   + GE   G  +CP+D  + +  L  DG+LYSA
Sbjct: 120 YNASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSA 179

Query: 187 TVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAI----EYGNY------VYFF 236
           T+ +FL ++ +I R+MG   +++T +Y + W+ EPHF+ +       G++      VYFF
Sbjct: 180 TLNNFLGTEPIILRNMGPHHSMKT-EYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFF 238

Query: 237 FREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDV 296
           FRE AVE +   + V +RVAR+CK DMGG+ R L++ WT+FLKARL CS P     YF+ 
Sbjct: 239 FRERAVESDCYAEQVVARVARVCKGDMGGA-RTLQRKWTTFLKARLACSAPNWQ-LYFNQ 296

Query: 297 LQSITDIIQIN-GIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWT 355
           LQ++  +   +    T  GVF  Q   +  SA+C + +++I++VF+G +KE       W 
Sbjct: 297 LQAMHTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWD 356

Query: 356 AVPEDKVPKPRPGCC-----AKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEP 410
               D VP PRPG C      +HG    Y +S++ PD  L+F+K HPLM+  V P    P
Sbjct: 357 RY-TDPVPSPRPGSCINNWHRRHG----YTSSLELPDNILNFVKKHPLMEEQVGPRWSRP 411

Query: 411 WFTKTRVRYRLTAISVDHSAG-PYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSV-LLEE 468
              K    +  T +  D   G     YTV+F+G+  G +LK +      SL   V L+EE
Sbjct: 412 LLVKKGTNF--THLVADRVTGLDGATYTVLFIGTGDGWLLKAV------SLGPWVHLIEE 463

Query: 469 IEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIAS 528
           ++ +          + + + SL L +    L+    S ++++P++ C +Y SC   C+ +
Sbjct: 464 LQLF----------DQEPMRSLVLSQSKKLLFAGSRSQLVQLPVADCMKYRSC-ADCVLA 512

Query: 529 RDPYCGW 535
           RDPYC W
Sbjct: 513 RDPYCAW 519


>gi|39777610 semaphorin 4B precursor [Homo sapiens]
          Length = 837

 Score =  263 bits (671), Expect = 8e-70
 Identities = 183/563 (32%), Positives = 282/563 (50%), Gaps = 71/563 (12%)

Query: 52  ESQHRLDFQLMLKIRD--TLYIAGRDQVYTV--NLNEMPKTEVIPNKKLTWRSRQQDREN 107
           E++H  ++  +L  RD  TLY+  R+ ++ +  NL+ +P  E    ++L W +  + ++ 
Sbjct: 63  EAEHISNYTALLLSRDGRTLYVGAREALFALSSNLSFLPGGEY---QELLWGADAEKKQQ 119

Query: 108 CAMKGKHKD-ECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEIS----- 161
           C+ KGK    +C N+IK+ +P +   +F CGT AF+PMC Y  +       +E       
Sbjct: 120 CSFKGKDPQRDCQNYIKILLPLSGSHLFTCGTAAFSPMCTYINMENFTLARDEKGNVLLE 179

Query: 162 -GLARCPFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSK--WI 218
            G  RCPFD    + AL  DG+LY+ TV+ F  +D  I RS     +LR  K +S   W+
Sbjct: 180 DGKGRCPFDPNFKSTALVVDGELYTGTVSSFQGNDPAISRSQ----SLRPTKTESSLNWL 235

Query: 219 KEPHFLHAIEY----------GNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQR 268
           ++P F+ +              + +YFFF E   E       + SR+ARICK D GG +R
Sbjct: 236 QDPAFVASAYIPESLGSLQGDDDKIYFFFSETGQEFEFFENTIVSRIARICKGDEGG-ER 294

Query: 269 VLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDIIQINGIPT------VVGVFTTQLN- 321
           VL++ WTSFLKA+L CS P D F  F+VLQ   D+  ++  P         GVFT+Q + 
Sbjct: 295 VLQQRWTSFLKAQLLCSRPDDGF-PFNVLQ---DVFTLSPSPQDWRDTLFYGVFTSQWHR 350

Query: 322 -SIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAE-AY 379
            +  GSAVC F+M D+++VF G +KE       W  V    VP PRPG C  +   E   
Sbjct: 351 GTTEGSAVCVFTMKDVQRVFSGLYKEVNRETQQWYTVTH-PVPTPRPGACITNSARERKI 409

Query: 380 KTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAISVDHSAGPYQNYTVI 439
            +S+  PD  L+F+K H LMD  V          + + RY+   ++V    G +  Y V+
Sbjct: 410 NSSLQLPDRVLNFLKDHFLMDGQV---RSRMLLLQPQARYQ--RVAVHRVPGLHHTYDVL 464

Query: 440 FVGSEAGMVLKVLAKTSPFSLNDSV-LLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHA 498
           F+G+  G + K +      S+   V ++EE++ ++           + V +L LD     
Sbjct: 465 FLGTGDGRLHKAV------SVGPRVHIIEELQIFS---------SGQPVQNLLLDTHRGL 509

Query: 499 LYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGSCGRVT---PGMLAEGYEQ 555
           LY A  S ++++P++ C  Y SC   C+ +RDPYC W S  SC  V+   P +    + Q
Sbjct: 510 LYAASHSGVVQVPMANCSLYRSC-GDCLLARDPYCAW-SGSSCKHVSLYQPQLATRPWIQ 567

Query: 556 DTEFGNTAHLGDCHEILPTSTTP 578
           D E  +   L     ++  S  P
Sbjct: 568 DIEGASAKDLCSASSVVSPSFVP 590


>gi|39777608 semaphorin 4B precursor [Homo sapiens]
          Length = 837

 Score =  263 bits (671), Expect = 8e-70
 Identities = 183/563 (32%), Positives = 282/563 (50%), Gaps = 71/563 (12%)

Query: 52  ESQHRLDFQLMLKIRD--TLYIAGRDQVYTV--NLNEMPKTEVIPNKKLTWRSRQQDREN 107
           E++H  ++  +L  RD  TLY+  R+ ++ +  NL+ +P  E    ++L W +  + ++ 
Sbjct: 63  EAEHISNYTALLLSRDGRTLYVGAREALFALSSNLSFLPGGEY---QELLWGADAEKKQQ 119

Query: 108 CAMKGKHKD-ECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEIS----- 161
           C+ KGK    +C N+IK+ +P +   +F CGT AF+PMC Y  +       +E       
Sbjct: 120 CSFKGKDPQRDCQNYIKILLPLSGSHLFTCGTAAFSPMCTYINMENFTLARDEKGNVLLE 179

Query: 162 -GLARCPFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSK--WI 218
            G  RCPFD    + AL  DG+LY+ TV+ F  +D  I RS     +LR  K +S   W+
Sbjct: 180 DGKGRCPFDPNFKSTALVVDGELYTGTVSSFQGNDPAISRSQ----SLRPTKTESSLNWL 235

Query: 219 KEPHFLHAIEY----------GNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQR 268
           ++P F+ +              + +YFFF E   E       + SR+ARICK D GG +R
Sbjct: 236 QDPAFVASAYIPESLGSLQGDDDKIYFFFSETGQEFEFFENTIVSRIARICKGDEGG-ER 294

Query: 269 VLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDIIQINGIPT------VVGVFTTQLN- 321
           VL++ WTSFLKA+L CS P D F  F+VLQ   D+  ++  P         GVFT+Q + 
Sbjct: 295 VLQQRWTSFLKAQLLCSRPDDGF-PFNVLQ---DVFTLSPSPQDWRDTLFYGVFTSQWHR 350

Query: 322 -SIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAE-AY 379
            +  GSAVC F+M D+++VF G +KE       W  V    VP PRPG C  +   E   
Sbjct: 351 GTTEGSAVCVFTMKDVQRVFSGLYKEVNRETQQWYTVTH-PVPTPRPGACITNSARERKI 409

Query: 380 KTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAISVDHSAGPYQNYTVI 439
            +S+  PD  L+F+K H LMD  V          + + RY+   ++V    G +  Y V+
Sbjct: 410 NSSLQLPDRVLNFLKDHFLMDGQV---RSRMLLLQPQARYQ--RVAVHRVPGLHHTYDVL 464

Query: 440 FVGSEAGMVLKVLAKTSPFSLNDSV-LLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHA 498
           F+G+  G + K +      S+   V ++EE++ ++           + V +L LD     
Sbjct: 465 FLGTGDGRLHKAV------SVGPRVHIIEELQIFS---------SGQPVQNLLLDTHRGL 509

Query: 499 LYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGSCGRVT---PGMLAEGYEQ 555
           LY A  S ++++P++ C  Y SC   C+ +RDPYC W S  SC  V+   P +    + Q
Sbjct: 510 LYAASHSGVVQVPMANCSLYRSC-GDCLLARDPYCAW-SGSSCKHVSLYQPQLATRPWIQ 567

Query: 556 DTEFGNTAHLGDCHEILPTSTTP 578
           D E  +   L     ++  S  P
Sbjct: 568 DIEGASAKDLCSASSVVSPSFVP 590


>gi|9910362 semaphorin sem2 [Homo sapiens]
          Length = 782

 Score =  254 bits (648), Expect = 4e-67
 Identities = 188/585 (32%), Positives = 272/585 (46%), Gaps = 63/585 (10%)

Query: 54  QHRLDFQLML--KIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMK 111
           Q  L+ Q M   + RD L++ G D +Y++ L++         +++ W  +   RE C  K
Sbjct: 53  QGSLNLQAMYLDEYRDRLFLGGLDALYSLRLDQAWPDP----REVLWPPQPGQREECVRK 108

Query: 112 GKHK-DECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEI---------S 161
           G+    EC NF++V  P N   +  CGT AF P C    L T+ + GE +         S
Sbjct: 109 GRDPLTECANFVRVLQPHNRTHLLACGTGAFQPTCA---LITVGHRGEHVLHLEPGSVES 165

Query: 162 GLARCPFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEP 221
           G  RCP +  +   + F DG+LY+   ADFL  +A+I+RS G   ALR+   D   + +P
Sbjct: 166 GRGRCPHEPSRPFASTFIDGELYTGLTADFLGREAMIFRSGGPRPALRSDS-DQSLLHDP 224

Query: 222 HFLHAIEY-------GNYVYFFFRE-IAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKH 273
            F+ A           + VYFFF E +            SRV R+C ND GG QRVL   
Sbjct: 225 RFVMAARIPENSDQDNDKVYFFFSETVPSPDGGSNHVTVSRVGRVCVNDAGG-QRVLVNK 283

Query: 274 WTSFLKARLNCSVPGD--SFFYFDVLQSITDIIQINGIPT-VVGVFTTQLNSIPGSAVCA 330
           W++FLKARL CSVPG   +  +FD L+ +  +    G    V  +F+T      G AVC 
Sbjct: 284 WSTFLKARLVCSVPGPGGAETHFDQLEDVFLLWPKAGKSLEVYALFSTVSAVFQGFAVCV 343

Query: 331 FSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEA---YKTSIDFPD 387
           + M DI +VF G F  +  P   W      KVP PRPG C     A+    + ++ D+PD
Sbjct: 344 YHMADIWEVFNGPFAHRDGPQHQWGPYG-GKVPFPRPGVCPSKMTAQPGRPFGSTKDYPD 402

Query: 388 ETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGM 447
           E L F ++HPLM   V P    P   KT +  +L  I VD        Y VIF+G+++G 
Sbjct: 403 EVLQFARAHPLMFWPVRPRHGRPVLVKTHLAQQLHQIVVDRVEAEDGTYDVIFLGTDSGS 462

Query: 448 VLKVLAKTSPFSLN-DSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSC 506
           VLKV+A  +  S   + V+LEE++ +         +    +  +++      LYV     
Sbjct: 463 VLKVIALQAGGSAEPEEVVLEELQVF---------KVPTPITEMEISVKRQMLYVGSRLG 513

Query: 507 IIRIPLSRCERYGSCKKSCIASRDPYCGWLSQGSCGRVTPGMLAEGY-EQDTEFGNTA-- 563
           + ++ L +CE YG+    C  +RDPYC W    SC    P +    +  QD   GN A  
Sbjct: 514 VAQLRLHQCETYGTACAECCLARDPYCAW-DGASCTHYRPSLGKRRFRRQDIRHGNPALQ 572

Query: 564 HLGDCHEILPTSTTPDYKIFG-------------GPTSGVRWEVQ 595
            LG   E           ++G              P + VRW +Q
Sbjct: 573 CLGQSQEEEAVGLVAATMVYGTEHNSTFLECLPKSPQAAVRWLLQ 617


>gi|21361914 semaphorin B [Homo sapiens]
          Length = 761

 Score =  233 bits (594), Expect = 7e-61
 Identities = 167/519 (32%), Positives = 265/519 (51%), Gaps = 54/519 (10%)

Query: 58  DFQLMLKIRD--TLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHK 115
           DF  +L   D  TLY+  R+ +  +++ + P    + N  + W +  + +  CA K K  
Sbjct: 63  DFDTLLLSGDGNTLYVGAREAILALDIQD-PGVPRLKNM-IPWPASDRKKSECAFKKKSN 120

Query: 116 D-ECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEY----DGEEISGLARCPFDA 170
           + +C NFI+V V  N   ++ CGT AF+P C +  L         + + + G  + PFD 
Sbjct: 121 ETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQSPFDP 180

Query: 171 RQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIK-EPHFLHAIEY 229
              + A+  DG LYS T+ +FL S+ ++ R++G    L+T  +  +W+  +  F+ AI  
Sbjct: 181 AHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNF-LRWLHHDASFVAAIPS 239

Query: 230 GNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGD 289
              VYFFF E A E +   +   SRVAR+CKND+GG +++L+K WT+FLKA+L C+ PG 
Sbjct: 240 TQVVYFFFEETASEFDFFERLHTSRVARVCKNDVGG-EKLLQKKWTTFLKAQLLCTQPGQ 298

Query: 290 SFFYFDVLQSITDIIQINGIPTVVGVFTT--QLNSIPGSAVCAFSMDDIEKVFKGRFKEQ 347
             F   +  ++         P +  VFT+  Q+     SAVCAFS+ DIE+VFKG++KE 
Sbjct: 299 LPFNV-IRHAVLLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKEL 357

Query: 348 KTPDSVWTAV--PEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPP 405
               S WT    PE     PRPG C+    +          D+ L+F+K H LMD  V  
Sbjct: 358 NKETSRWTTYRGPE---TNPRPGSCSVGPSS----------DKALTFMKDHFLMDEQV-- 402

Query: 406 IADEPWFTKTRVRYRLTAISVDHSAG-PYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSV 464
               P   K+ V Y  T ++V+ + G    ++ V+++G+  G + K +        + + 
Sbjct: 403 -VGTPLLVKSGVEY--TRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGD----SSAH 455

Query: 465 LLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKS 524
           L+EEI+ +          + + V +LQL     A++V FS  + R+P + C  Y SC   
Sbjct: 456 LVEEIQLF---------PDPEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVYESC-VD 505

Query: 525 CIASRDPYCGW--LSQGSCGRVTPGMLAEGYEQDTEFGN 561
           C+ +RDP+C W   S+  C    P +    ++QD E GN
Sbjct: 506 CVLARDPHCAWDPESRTCCLLSAPNL--NSWKQDMERGN 542


>gi|19923279 semaphorin W [Homo sapiens]
          Length = 770

 Score =  224 bits (570), Expect = 4e-58
 Identities = 153/483 (31%), Positives = 247/483 (51%), Gaps = 41/483 (8%)

Query: 68  TLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHNFIKVFVP 127
           TLY+  RD ++ ++L   P +   P +++ W   +  R+NC  KGK +DECHNF+++   
Sbjct: 76  TLYVGARDTIFALSL---PFSGERP-RRIDWMVPEAHRQNCRKKGKKEDECHNFVQILAI 131

Query: 128 RNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFADGKLYSAT 187
            N   +  CGT AF+P C    +S  +      SG  +CPF+  Q + A+ A G LY+AT
Sbjct: 132 ANASHLLTCGTFAFDPKCGVIDVSRFQQVERLESGRGKCPFEPAQRSAAVMAGGVLYAAT 191

Query: 188 VADFLASDAVIYRSMGDGSA-LRTIKYDSKWIKEPHFLHAI-----EYG-----NYVYFF 236
           V ++L ++ +I R++G     +RT    S W+  P F+ A+     E+G     + +YFF
Sbjct: 192 VKNYLGTEPIITRAVGRAEDWIRTDTLPS-WLNAPAFVAAVALSPAEWGDEDGDDEIYFF 250

Query: 237 FREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDV 296
           F E +   ++  +    RVAR+C  D+GG ++ L++ WT+FLKA L C  P +      V
Sbjct: 251 FTETSRAFDSYERIKVPRVARVCAGDLGG-RKTLQQRWTTFLKADLLCPGP-EHGRASSV 308

Query: 297 LQSITDIIQI--NGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVW 354
           LQ +  +      G P   G+F++Q      SAVCAF   DI  V  G F+E K   +  
Sbjct: 309 LQDVAVLRPELGAGTPIFYGIFSSQWEGATISAVCAFRPQDIRTVLNGPFRELKHDCNRG 368

Query: 355 TAVPEDKVPKPRPGCCAKHGL-AEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFT 413
             V ++ VP+PRPG C  + +    + +S+  PD  L+FI+ HPLMD  V P    P   
Sbjct: 369 LPVVDNDVPQPRPGECITNNMKLRHFGSSLSLPDRVLTFIRDHPLMDRPVFPADGHPLLV 428

Query: 414 KTRVRY-RLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAY 472
            T   Y R+ A  V   +G  + Y V+++G+E G + + +   +  S     +LE++  +
Sbjct: 429 TTDTAYLRVVAHRVTSLSG--KEYDVLYLGTEDGHLHRAVRIGAQLS-----VLEDLALF 481

Query: 473 NHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPY 532
                     E + V +++L   H  L V   + + ++  + C R  SC + CI ++DP 
Sbjct: 482 ---------PEPQPVENMKL--YHSWLLVGSRTEVTQVNTTNCGRLQSCSE-CILAQDPV 529

Query: 533 CGW 535
           C W
Sbjct: 530 CAW 532


>gi|28872814 semaphorin 4G [Homo sapiens]
          Length = 843

 Score =  221 bits (564), Expect = 2e-57
 Identities = 164/541 (30%), Positives = 253/541 (46%), Gaps = 59/541 (10%)

Query: 18  LRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQLMLKIRDTLYIAGRDQV 77
           LR  S   D  P  T+ Y        F+G+     +       L+ +    L +  R  +
Sbjct: 23  LRRPSRELDATPRMTIPYEELSGTRHFKGQAQNYSTL------LLEEASARLLVGARGAL 76

Query: 78  YTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKD-ECHNFIKVFVPRNDEMVFVC 136
           ++++ N++       +K++ W +  + +  C  KGK+   EC N ++     N   ++ C
Sbjct: 77  FSLSANDIGDGA---HKEIHWEASPEMQSKCHQKGKNNQTECFNHVRFLQRLNSTHLYAC 133

Query: 137 GTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFADGKLYSATVADFLASDA 196
           GT+AF P+C                G  +CP+D  +    L  DG LY+AT  +F +   
Sbjct: 134 GTHAFQPLCAAIDAEAFTLPTSFEEGKEKCPYDPARGFTGLIIDGGLYTATRYEFRSIPD 193

Query: 197 VIYRSMGDGSALRTIKYDSKWIKEPHFLH----------AIEYGNYVYFFFREIAVEHNN 246
           +  R      +LRT +    W+ +  F+           A+   + VY+FF E A E  +
Sbjct: 194 I--RRSRHPHSLRTEETPMHWLNDAEFVFSVLVRESKASAVGDDDKVYYFFTERATEEGS 251

Query: 247 LGKAVYSR-------VARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQS 299
            G    SR       VAR+CK D+GG +++L+K WTSFLKARL C +P      ++ L+ 
Sbjct: 252 -GSFTQSRSSHRVARVARVCKGDLGG-KKILQKKWTSFLKARLICHIP-----LYETLRG 304

Query: 300 ITDI-IQINGIPTVVGVFT--TQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTA 356
           +  +  + +        FT  TQ  ++  SA+C + + +I+ VF G + E +     W  
Sbjct: 305 VCSLDAETSSRTHFYAAFTLSTQWKTLEASAICRYDLAEIQAVFAGPYMEYQDGSRRWGR 364

Query: 357 VPEDKVPKPRPGCCAKHGL-AEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKT 415
             E  VP+PRPG C    L ++ Y +S D P   L F+K HPLM   V P    P   K 
Sbjct: 365 Y-EGGVPEPRPGSCITDSLRSQGYNSSQDLPSLVLDFVKLHPLMARPVVPTRGRPLLLKR 423

Query: 416 RVRY-RLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNH 474
            +RY  LT   V   AGP   Y ++F+G+  G + K +   S        ++EE + +  
Sbjct: 424 NIRYTHLTGTPVTTPAGP--TYDLLFLGTADGWIHKAVVLGSGMH-----IIEETQVFRE 476

Query: 475 AKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCG 534
           ++ S EN     VISL      H+LYV   S +I++PLS C RY SC   CI +RDPYCG
Sbjct: 477 SQ-SVEN----LVISLL----QHSLYVGAPSGVIQLPLSSCSRYRSC-YDCILARDPYCG 526

Query: 535 W 535
           W
Sbjct: 527 W 527


>gi|4504237 semaphorin 7A isoform 1 preproprotein [Homo sapiens]
          Length = 666

 Score =  134 bits (337), Expect = 4e-31
 Identities = 126/441 (28%), Positives = 192/441 (43%), Gaps = 59/441 (13%)

Query: 115 KDECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTN 174
           K +C N+I + + R  E +  CGTNA +P C      T+   GE + G A  PF   + +
Sbjct: 123 KRDCENYITL-LERRSEGLLACGTNARHPSCWNLVNGTVVPLGE-MRGYA--PFSPDENS 178

Query: 175 VALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAI------E 228
           + LF   ++YS             +R +   S L T       ++ P F+ A        
Sbjct: 179 LVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYT---SDTVMQNPQFIKATIVHQDQA 235

Query: 229 YGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPG 288
           Y + +Y+FFRE   + N       SRVA++C+ D GG   +    W +FLKA L CS   
Sbjct: 236 YDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVCSDAA 295

Query: 289 DSFFYFDVLQSITDIIQING---IPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFK 345
            +   F+ LQ +  +   +G      V GVF+   N    SAVC +S+ DI+KVF  R  
Sbjct: 296 TN-KNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY---SAVCVYSLGDIDKVF--RTS 349

Query: 346 EQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPP 405
             K   S         +P PRPG C               P ET      HP +   V P
Sbjct: 350 SLKGYHS--------SLPNPRPGKC--------LPDQQPIPTETFQVADRHPEVAQRVEP 393

Query: 406 IA--DEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVL---AKTSPFSL 460
           +     P F  ++  Y+  A+     A   + + V+++ ++ G + KV+    +   F+ 
Sbjct: 394 MGPLKTPLF-HSKYHYQKVAVH-RMQASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAF 451

Query: 461 NDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGS 520
           N    + EI+ +  A           + ++ LD +   LYV+    + ++PL  CE YG 
Sbjct: 452 N----IMEIQPFRRAAA---------IQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGG 498

Query: 521 CKKSCIASRDPYCGWLSQGSC 541
               C+ SRDPYCGW  QG C
Sbjct: 499 GCHGCLMSRDPYCGW-DQGRC 518


>gi|225637520 semaphorin 7A isoform 2 preproprotein [Homo sapiens]
          Length = 652

 Score =  133 bits (335), Expect = 7e-31
 Identities = 125/441 (28%), Positives = 192/441 (43%), Gaps = 59/441 (13%)

Query: 115 KDECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTN 174
           + +C N+I + + R  E +  CGTNA +P C      T+   GE + G A  PF   + +
Sbjct: 109 RTDCENYITL-LERRSEGLLACGTNARHPSCWNLVNGTVVPLGE-MRGYA--PFSPDENS 164

Query: 175 VALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAI------E 228
           + LF   ++YS             +R +   S L T       ++ P F+ A        
Sbjct: 165 LVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYT---SDTVMQNPQFIKATIVHQDQA 221

Query: 229 YGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPG 288
           Y + +Y+FFRE   + N       SRVA++C+ D GG   +    W +FLKA L CS   
Sbjct: 222 YDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVCSDAA 281

Query: 289 DSFFYFDVLQSITDIIQING---IPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFK 345
            +   F+ LQ +  +   +G      V GVF+   N    SAVC +S+ DI+KVF  R  
Sbjct: 282 TN-KNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY---SAVCVYSLGDIDKVF--RTS 335

Query: 346 EQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPP 405
             K   S         +P PRPG C               P ET      HP +   V P
Sbjct: 336 SLKGYHS--------SLPNPRPGKC--------LPDQQPIPTETFQVADRHPEVAQRVEP 379

Query: 406 IA--DEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVL---AKTSPFSL 460
           +     P F  ++  Y+  A+     A   + + V+++ ++ G + KV+    +   F+ 
Sbjct: 380 MGPLKTPLF-HSKYHYQKVAVH-RMQASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAF 437

Query: 461 NDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGS 520
           N    + EI+ +  A           + ++ LD +   LYV+    + ++PL  CE YG 
Sbjct: 438 N----IMEIQPFRRAAA---------IQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGG 484

Query: 521 CKKSCIASRDPYCGWLSQGSC 541
               C+ SRDPYCGW  QG C
Sbjct: 485 GCHGCLMSRDPYCGW-DQGRC 504


>gi|225637524 semaphorin 7A isoform 3 [Homo sapiens]
          Length = 501

 Score =  116 bits (291), Expect = 9e-26
 Identities = 108/389 (27%), Positives = 166/389 (42%), Gaps = 55/389 (14%)

Query: 167 PFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHA 226
           PF   + ++ LF   ++YS             +R +   S L T       ++ P F+ A
Sbjct: 6   PFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYT---SDTVMQNPQFIKA 62

Query: 227 I------EYGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKA 280
                   Y + +Y+FFRE   + N       SRVA++C+ D GG   +    W +FLKA
Sbjct: 63  TIVHQDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKA 122

Query: 281 RLNCSVPGDSFFYFDVLQSITDIIQING---IPTVVGVFTTQLNSIPGSAVCAFSMDDIE 337
            L CS    +   F+ LQ +  +   +G      V GVF+   N    SAVC +S+ DI+
Sbjct: 123 MLVCSDAATN-KNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY---SAVCVYSLGDID 178

Query: 338 KVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHP 397
           KVF  R    K   S         +P PRPG C               P ET      HP
Sbjct: 179 KVF--RTSSLKGYHS--------SLPNPRPGKC--------LPDQQPIPTETFQVADRHP 220

Query: 398 LMDSAVPPIA--DEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVL--- 452
            +   V P+     P F  ++  Y+  A+     A   + + V+++ ++ G + KV+   
Sbjct: 221 EVAQRVEPMGPLKTPLF-HSKYHYQKVAVH-RMQASHGETFHVLYLTTDRGTIHKVVEPG 278

Query: 453 AKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPL 512
            +   F+ N    + EI+ +  A           + ++ LD +   LYV+    + ++PL
Sbjct: 279 EQEHSFAFN----IMEIQPFRRAAA---------IQTMSLDAERRKLYVSSQWEVSQVPL 325

Query: 513 SRCERYGSCKKSCIASRDPYCGWLSQGSC 541
             CE YG     C+ SRDPYCGW  QG C
Sbjct: 326 DLCEVYGGGCHGCLMSRDPYCGW-DQGRC 353


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.402 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,087,344
Number of Sequences: 37866
Number of extensions: 2149499
Number of successful extensions: 8287
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 198
Number of HSP's that attempted gapping in prelim test: 7583
Number of HSP's gapped (non-prelim): 682
length of query: 1017
length of database: 18,247,518
effective HSP length: 112
effective length of query: 905
effective length of database: 14,006,526
effective search space: 12675906030
effective search space used: 12675906030
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.