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Search of human proteins with 119943112
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|119943112 7-dehydrocholesterol reductase [Homo sapiens]
(475 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|119943112 7-dehydrocholesterol reductase [Homo sapiens] 1017 0.0
gi|37595752 lamin B receptor [Homo sapiens] 262 6e-70
gi|37595750 lamin B receptor [Homo sapiens] 262 6e-70
gi|117414150 transmembrane 7 superfamily member 2 [Homo sapiens] 261 1e-69
gi|17864088 sorting nexin 13 [Homo sapiens] 32 1.6
gi|117168245 ATPase, aminophospholipid transporter-like, Class I... 30 3.7
gi|5453906 CDP-diacylglycerol-inositol 3-phosphatidyltransferase... 30 6.3
gi|42717999 dystrobrevin alpha isoform 2 [Homo sapiens] 30 6.3
gi|42718005 dystrobrevin alpha isoform 1 [Homo sapiens] 30 6.3
gi|42718003 dystrobrevin alpha isoform 3 [Homo sapiens] 30 6.3
gi|42718001 dystrobrevin alpha isoform 4 [Homo sapiens] 30 6.3
gi|42717997 dystrobrevin alpha isoform 5 [Homo sapiens] 30 6.3
gi|42717994 dystrobrevin alpha isoform 7 [Homo sapiens] 30 6.3
gi|189571587 dystrobrevin alpha isoform 9 [Homo sapiens] 30 6.3
gi|119433677 chloride channel 1, skeletal muscle [Homo sapiens] 29 8.2
>gi|119943112 7-dehydrocholesterol reductase [Homo sapiens]
Length = 475
Score = 1017 bits (2630), Expect = 0.0
Identities = 475/475 (100%), Positives = 475/475 (100%)
Query: 1 MAAKSQPNIPKAKSLDGVTNDRTASQGQWGRAWEVDWFSLASVIFLLLFAPFIVYYFIMA 60
MAAKSQPNIPKAKSLDGVTNDRTASQGQWGRAWEVDWFSLASVIFLLLFAPFIVYYFIMA
Sbjct: 1 MAAKSQPNIPKAKSLDGVTNDRTASQGQWGRAWEVDWFSLASVIFLLLFAPFIVYYFIMA 60
Query: 61 CDQYSCALTGPVVDIVTGHARLSDIWAKTPPITRKAAQLYTLWVTFQVLLYTSLPDFCHK 120
CDQYSCALTGPVVDIVTGHARLSDIWAKTPPITRKAAQLYTLWVTFQVLLYTSLPDFCHK
Sbjct: 61 CDQYSCALTGPVVDIVTGHARLSDIWAKTPPITRKAAQLYTLWVTFQVLLYTSLPDFCHK 120
Query: 121 FLPGYVGGIQEGAVTPAGVVNKYQINGLQAWLLTHLLWFANAHLLSWFSPTIIFDNWIPL 180
FLPGYVGGIQEGAVTPAGVVNKYQINGLQAWLLTHLLWFANAHLLSWFSPTIIFDNWIPL
Sbjct: 121 FLPGYVGGIQEGAVTPAGVVNKYQINGLQAWLLTHLLWFANAHLLSWFSPTIIFDNWIPL 180
Query: 181 LWCANILGYAVSTFAMVKGYFFPTSARDCKFTGNFFYNYMMGIEFNPRIGKWFDFKLFFN 240
LWCANILGYAVSTFAMVKGYFFPTSARDCKFTGNFFYNYMMGIEFNPRIGKWFDFKLFFN
Sbjct: 181 LWCANILGYAVSTFAMVKGYFFPTSARDCKFTGNFFYNYMMGIEFNPRIGKWFDFKLFFN 240
Query: 241 GRPGIVAWTLINLSFAAKQRELHSHVTNAMVLVNVLQAIYVIDFFWNETWYLKTIDICHD 300
GRPGIVAWTLINLSFAAKQRELHSHVTNAMVLVNVLQAIYVIDFFWNETWYLKTIDICHD
Sbjct: 241 GRPGIVAWTLINLSFAAKQRELHSHVTNAMVLVNVLQAIYVIDFFWNETWYLKTIDICHD 300
Query: 301 HFGWYLGWGDCVWLPYLYTLQGLYLVYHPVQLSTPHAVGVLLLGLVGYYIFRVANHQKDL 360
HFGWYLGWGDCVWLPYLYTLQGLYLVYHPVQLSTPHAVGVLLLGLVGYYIFRVANHQKDL
Sbjct: 301 HFGWYLGWGDCVWLPYLYTLQGLYLVYHPVQLSTPHAVGVLLLGLVGYYIFRVANHQKDL 360
Query: 361 FRRTDGRCLIWGRKPKVIECSYTSADGQRHHSKLLVSGFWGVARHFNYVGDLMGSLAYCL 420
FRRTDGRCLIWGRKPKVIECSYTSADGQRHHSKLLVSGFWGVARHFNYVGDLMGSLAYCL
Sbjct: 361 FRRTDGRCLIWGRKPKVIECSYTSADGQRHHSKLLVSGFWGVARHFNYVGDLMGSLAYCL 420
Query: 421 ACGGGHLLPYFYIIYMAILLTHRCLRDEHRCASKYGRDWERYTAAVPYRLLPGIF 475
ACGGGHLLPYFYIIYMAILLTHRCLRDEHRCASKYGRDWERYTAAVPYRLLPGIF
Sbjct: 421 ACGGGHLLPYFYIIYMAILLTHRCLRDEHRCASKYGRDWERYTAAVPYRLLPGIF 475
>gi|37595752 lamin B receptor [Homo sapiens]
Length = 615
Score = 262 bits (669), Expect = 6e-70
Identities = 155/449 (34%), Positives = 233/449 (51%), Gaps = 40/449 (8%)
Query: 31 RAWEVDWFSLASVIFLLLFAPFIVYYFIMACDQYSCALTGPVVDIVTGHARLSDIWAKTP 90
RA ++++ + V ++ P ++ ++ C Q +L ++ L ++W
Sbjct: 203 RAKDLEFGGVPGVFLIMFGLPVFLFLLLLMCKQKDPSL----LNFPPPLPALYELWET-- 256
Query: 91 PITRKAAQLYTLWVTFQVLLYTSLPDFCHKFLPGYVGGIQEGAVTPAGVVNKYQINGLQA 150
+ +Y LW QVL Y LP +G + EG G KY++NG A
Sbjct: 257 ----RVFGVYLLWFLIQVLFY---------LLP--IGKVVEGTPLIDGRRLKYRLNGFYA 301
Query: 151 WLLTHLLWFANAHLLSWFSPTIIFDNWIPLLWCANILGYAVSTFAMVKGYFFPTSARDCK 210
++LT + L ++ +++ A + +S + ++ P +
Sbjct: 302 FILTSAV--IGTSLFQGVEFHYVYSHFLQFALAATVFCVVLSVYLYMRSLKAPRNDLSPA 359
Query: 211 FTGNFFYNYMMGIEFNPRIGKWFDFKLFFNGRPGIVAWTLINLSFAAKQRELHSHVTN-- 268
+GN Y++ +G E NPRIG FD K F RPG++ W +INL + ++
Sbjct: 360 SSGNAVYDFFIGRELNPRIGT-FDLKYFCELRPGLIGWVVINLVMLLAEMKIQDRAVPSL 418
Query: 269 AMVLVNVLQAIYVIDFFWNETWYLKTIDICHDHFGWYLGWGDCVWLPYLYTLQGLYLVYH 328
AM+LVN Q +YV+D WNE L T+DI HD FG+ L +GD VW+P++Y+ Q YLV H
Sbjct: 419 AMILVNSFQLLYVVDALWNEEALLTTMDIIHDGFGFMLAFGDLVWVPFIYSFQAFYLVSH 478
Query: 329 PVQLSTPHAVGVLLLGLVGYYIFRVANHQKDLFRRTDGRCLIWGRKPKV--IECSYTSAD 386
P ++S P A +++L L GY IFR AN QK+ FR+ PK+ ++ +TS
Sbjct: 479 PNEVSWPMASLIIVLKLCGYVIFRGANSQKNAFRKNPS-------DPKLAHLKTIHTSTG 531
Query: 387 GQRHHSKLLVSGFWGVARHFNYVGDLMGSLAYCLACGGGHLLPYFYIIYMAILLTHRCLR 446
LLVSG+WG RH NY+GDL+ +LA+ L CG H+LPYFYIIY +LL HR R
Sbjct: 532 -----KNLLVSGWWGFVRHPNYLGDLIMALAWSLPCGFNHILPYFYIIYFTMLLVHREAR 586
Query: 447 DEHRCASKYGRDWERYTAAVPYRLLPGIF 475
DE+ C KYG WE+Y VPYR+ P I+
Sbjct: 587 DEYHCKKKYGVAWEKYCQRVPYRIFPYIY 615
>gi|37595750 lamin B receptor [Homo sapiens]
Length = 615
Score = 262 bits (669), Expect = 6e-70
Identities = 155/449 (34%), Positives = 233/449 (51%), Gaps = 40/449 (8%)
Query: 31 RAWEVDWFSLASVIFLLLFAPFIVYYFIMACDQYSCALTGPVVDIVTGHARLSDIWAKTP 90
RA ++++ + V ++ P ++ ++ C Q +L ++ L ++W
Sbjct: 203 RAKDLEFGGVPGVFLIMFGLPVFLFLLLLMCKQKDPSL----LNFPPPLPALYELWET-- 256
Query: 91 PITRKAAQLYTLWVTFQVLLYTSLPDFCHKFLPGYVGGIQEGAVTPAGVVNKYQINGLQA 150
+ +Y LW QVL Y LP +G + EG G KY++NG A
Sbjct: 257 ----RVFGVYLLWFLIQVLFY---------LLP--IGKVVEGTPLIDGRRLKYRLNGFYA 301
Query: 151 WLLTHLLWFANAHLLSWFSPTIIFDNWIPLLWCANILGYAVSTFAMVKGYFFPTSARDCK 210
++LT + L ++ +++ A + +S + ++ P +
Sbjct: 302 FILTSAV--IGTSLFQGVEFHYVYSHFLQFALAATVFCVVLSVYLYMRSLKAPRNDLSPA 359
Query: 211 FTGNFFYNYMMGIEFNPRIGKWFDFKLFFNGRPGIVAWTLINLSFAAKQRELHSHVTN-- 268
+GN Y++ +G E NPRIG FD K F RPG++ W +INL + ++
Sbjct: 360 SSGNAVYDFFIGRELNPRIGT-FDLKYFCELRPGLIGWVVINLVMLLAEMKIQDRAVPSL 418
Query: 269 AMVLVNVLQAIYVIDFFWNETWYLKTIDICHDHFGWYLGWGDCVWLPYLYTLQGLYLVYH 328
AM+LVN Q +YV+D WNE L T+DI HD FG+ L +GD VW+P++Y+ Q YLV H
Sbjct: 419 AMILVNSFQLLYVVDALWNEEALLTTMDIIHDGFGFMLAFGDLVWVPFIYSFQAFYLVSH 478
Query: 329 PVQLSTPHAVGVLLLGLVGYYIFRVANHQKDLFRRTDGRCLIWGRKPKV--IECSYTSAD 386
P ++S P A +++L L GY IFR AN QK+ FR+ PK+ ++ +TS
Sbjct: 479 PNEVSWPMASLIIVLKLCGYVIFRGANSQKNAFRKNPS-------DPKLAHLKTIHTSTG 531
Query: 387 GQRHHSKLLVSGFWGVARHFNYVGDLMGSLAYCLACGGGHLLPYFYIIYMAILLTHRCLR 446
LLVSG+WG RH NY+GDL+ +LA+ L CG H+LPYFYIIY +LL HR R
Sbjct: 532 -----KNLLVSGWWGFVRHPNYLGDLIMALAWSLPCGFNHILPYFYIIYFTMLLVHREAR 586
Query: 447 DEHRCASKYGRDWERYTAAVPYRLLPGIF 475
DE+ C KYG WE+Y VPYR+ P I+
Sbjct: 587 DEYHCKKKYGVAWEKYCQRVPYRIFPYIY 615
>gi|117414150 transmembrane 7 superfamily member 2 [Homo sapiens]
Length = 418
Score = 261 bits (667), Expect = 1e-69
Identities = 160/431 (37%), Positives = 227/431 (52%), Gaps = 35/431 (8%)
Query: 46 LLLFAPFIVYYFIMACDQYSCALTGPVVDIVTGHARLSDIWAKTPPITRKAAQLYTLWVT 105
LLL P +++ ++A L GP + L +W+ +A L+ W+
Sbjct: 22 LLLLLPATMFHLLLAARSGPARLLGPPASL----PGLEVLWSP------RALLLWLAWLG 71
Query: 106 FQVLLYTSLPDFCHKFLPGYVGGIQEGAVTPAGVVNKYQINGLQAWLLTHLLWFANAHLL 165
Q LY LP + EG +Y ING QA +LT LL +
Sbjct: 72 LQAALY---------LLPARK--VAEGQELKDKSRLRYPINGFQALVLTALL--VGLGMS 118
Query: 166 SWFSPTIIFDNWIPLLWCANILGYAVSTFAMVKGYFFPTSA-RDCKFTGNFFYNYMMGIE 224
+ + + +PL + A + + S F +K P SA +GN Y++ +G E
Sbjct: 119 AGLPLGALPEMLLPLAFVATLTAFIFSLFLYMKAQVAPVSALAPGGNSGNPIYDFFLGRE 178
Query: 225 FNPRIGKWFDFKLFFNGRPGIVAWTLINLSFAAKQRELHSHVTNAMVLVNVLQAIYVIDF 284
NPRI +FDFK F RPG++ W LINL+ K+ EL + AM LVN Q +YV D
Sbjct: 179 LNPRIC-FFDFKYFCELRPGLIGWVLINLALLMKEAELRGSPSLAMWLVNGFQLLYVGDA 237
Query: 285 FWNETWYLKTIDICHDHFGWYLGWGDCVWLPYLYTLQGLYLVYHPVQLSTPHAVGVLLLG 344
W+E L T+DI HD FG+ L +GD W+P+ Y+LQ +L++HP L P A + L+
Sbjct: 238 LWHEEAVLTTMDITHDGFGFMLAFGDMAWVPFTYSLQAQFLLHHPQPLGLPMASVICLIN 297
Query: 345 LVGYYIFRVANHQKDLFRRTDGRCLIWGRKPKVIECSYTSADGQRHHSKLLVSGFWGVAR 404
GYYIFR AN QK+ FR+ + G + + ++A G+ KLLVSG+WG+ R
Sbjct: 298 ATGYYIFRGANSQKNTFRKNPSDPRVAGLE------TISTATGR----KLLVSGWWGMVR 347
Query: 405 HFNYVGDLMGSLAYCLACGGGHLLPYFYIIYMAILLTHRCLRDEHRCASKYGRDWERYTA 464
H NY+GDL+ +LA+ L CG HLLPYFY++Y LL HR RDE +C KYG W+ Y
Sbjct: 348 HPNYLGDLIMALAWSLPCGVSHLLPYFYLLYFTALLVHREARDERQCLQKYGLAWQEYCR 407
Query: 465 AVPYRLLPGIF 475
VPYR++P I+
Sbjct: 408 RVPYRIMPYIY 418
>gi|17864088 sorting nexin 13 [Homo sapiens]
Length = 957
Score = 31.6 bits (70), Expect = 1.6
Identities = 16/40 (40%), Positives = 22/40 (55%), Gaps = 8/40 (20%)
Query: 24 ASQGQWGRAWEVDWFSLASVIFLLLFAPFIVYY--FIMAC 61
AS WG W SL V+FL+ F PF+++Y F + C
Sbjct: 5 ASLSIWG------WGSLGIVLFLITFGPFVIFYLTFYILC 38
>gi|117168245 ATPase, aminophospholipid transporter-like, Class I,
type 8A, member 2 [Homo sapiens]
Length = 1188
Score = 30.4 bits (67), Expect = 3.7
Identities = 23/80 (28%), Positives = 38/80 (47%), Gaps = 17/80 (21%)
Query: 244 GIVAWT------LINLSFAAKQRELHSHVTNAMVLV--NVLQAIYVID----FFWNET-- 289
GIV +T + N + A +R VTN +LV +L + ++ +WN +
Sbjct: 284 GIVVYTGHDTKLMQNSTKAPLKRSNVEKVTNVQILVLFGILLVMALVSSAGALYWNRSHG 343
Query: 290 ---WYLKTIDICHDHFGWYL 306
WY+K +D D+FG+ L
Sbjct: 344 EKNWYIKKMDTTSDNFGYNL 363
>gi|5453906 CDP-diacylglycerol-inositol 3-phosphatidyltransferase
[Homo sapiens]
Length = 213
Score = 29.6 bits (65), Expect = 6.3
Identities = 14/37 (37%), Positives = 20/37 (54%), Gaps = 4/37 (10%)
Query: 181 LWCANILGYAVSTFAMVKGYFFPTSARDCKFTGNFFY 217
L+ N++GYA FA++ YF P C T + FY
Sbjct: 8 LFVPNLIGYARIVFAIISFYFMPC----CPLTASSFY 40
>gi|42717999 dystrobrevin alpha isoform 2 [Homo sapiens]
Length = 686
Score = 29.6 bits (65), Expect = 6.3
Identities = 12/30 (40%), Positives = 19/30 (63%)
Query: 312 VWLPYLYTLQGLYLVYHPVQLSTPHAVGVL 341
VWLP L+ L + V+HPV+ S H+ ++
Sbjct: 223 VWLPLLHRLANVENVFHPVECSYCHSESMM 252
>gi|42718005 dystrobrevin alpha isoform 1 [Homo sapiens]
Length = 743
Score = 29.6 bits (65), Expect = 6.3
Identities = 12/30 (40%), Positives = 19/30 (63%)
Query: 312 VWLPYLYTLQGLYLVYHPVQLSTPHAVGVL 341
VWLP L+ L + V+HPV+ S H+ ++
Sbjct: 223 VWLPLLHRLANVENVFHPVECSYCHSESMM 252
>gi|42718003 dystrobrevin alpha isoform 3 [Homo sapiens]
Length = 570
Score = 29.6 bits (65), Expect = 6.3
Identities = 12/30 (40%), Positives = 19/30 (63%)
Query: 312 VWLPYLYTLQGLYLVYHPVQLSTPHAVGVL 341
VWLP L+ L + V+HPV+ S H+ ++
Sbjct: 223 VWLPLLHRLANVENVFHPVECSYCHSESMM 252
>gi|42718001 dystrobrevin alpha isoform 4 [Homo sapiens]
Length = 567
Score = 29.6 bits (65), Expect = 6.3
Identities = 12/30 (40%), Positives = 19/30 (63%)
Query: 312 VWLPYLYTLQGLYLVYHPVQLSTPHAVGVL 341
VWLP L+ L + V+HPV+ S H+ ++
Sbjct: 223 VWLPLLHRLANVENVFHPVECSYCHSESMM 252
>gi|42717997 dystrobrevin alpha isoform 5 [Homo sapiens]
Length = 513
Score = 29.6 bits (65), Expect = 6.3
Identities = 12/30 (40%), Positives = 19/30 (63%)
Query: 312 VWLPYLYTLQGLYLVYHPVQLSTPHAVGVL 341
VWLP L+ L + V+HPV+ S H+ ++
Sbjct: 223 VWLPLLHRLANVENVFHPVECSYCHSESMM 252
>gi|42717994 dystrobrevin alpha isoform 7 [Homo sapiens]
Length = 374
Score = 29.6 bits (65), Expect = 6.3
Identities = 12/30 (40%), Positives = 19/30 (63%)
Query: 312 VWLPYLYTLQGLYLVYHPVQLSTPHAVGVL 341
VWLP L+ L + V+HPV+ S H+ ++
Sbjct: 223 VWLPLLHRLANVENVFHPVECSYCHSESMM 252
>gi|189571587 dystrobrevin alpha isoform 9 [Homo sapiens]
Length = 371
Score = 29.6 bits (65), Expect = 6.3
Identities = 12/30 (40%), Positives = 19/30 (63%)
Query: 312 VWLPYLYTLQGLYLVYHPVQLSTPHAVGVL 341
VWLP L+ L + V+HPV+ S H+ ++
Sbjct: 223 VWLPLLHRLANVENVFHPVECSYCHSESMM 252
>gi|119433677 chloride channel 1, skeletal muscle [Homo sapiens]
Length = 988
Score = 29.3 bits (64), Expect = 8.2
Identities = 18/44 (40%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 100 YTLWVTFQVLLYTSLPDFCHKFLPGYVG-GIQEGAVTPAGVVNK 142
+ +WVTF ++L FCH P VG GI E GVV K
Sbjct: 161 FLVWVTFPLVLILFSALFCHLISPQAVGSGIPEMKTILRGVVLK 204
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.329 0.143 0.497
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,939,960
Number of Sequences: 37866
Number of extensions: 823569
Number of successful extensions: 1776
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1751
Number of HSP's gapped (non-prelim): 15
length of query: 475
length of database: 18,247,518
effective HSP length: 106
effective length of query: 369
effective length of database: 14,233,722
effective search space: 5252243418
effective search space used: 5252243418
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.