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Search of human proteins with 11991660
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|11991660 sema domain, transmembrane domain (TM), and
cytoplasmic domain, (semaphorin) 6A [Homo sapiens]
(1030 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|11991660 sema domain, transmembrane domain (TM), and cytoplas... 2103 0.0
gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens] 883 0.0
gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens] 877 0.0
gi|24234729 semaphorin 6D isoform 1 precursor [Homo sapiens] 858 0.0
gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens] 844 0.0
gi|24234744 semaphorin 6D isoform 5 precursor [Homo sapiens] 738 0.0
gi|19718780 semaphorin 6B precursor [Homo sapiens] 733 0.0
gi|24234732 semaphorin 6D isoform 6 precursor [Homo sapiens] 621 e-178
gi|16306552 semaphorin Y [Homo sapiens] 561 e-160
gi|5174673 semaphorin 3A precursor [Homo sapiens] 313 5e-85
gi|147904700 semaphorin 5A [Homo sapiens] 310 6e-84
gi|4759092 semaphorin 3B isoform 1 precursor [Homo sapiens] 306 5e-83
gi|54607089 semaphorin 3B isoform 2 precursor [Homo sapiens] 303 7e-82
gi|91982767 semaphorin 5B isoform 1 [Homo sapiens] 289 8e-78
gi|41406086 semaphorin 3D [Homo sapiens] 289 1e-77
gi|6912650 semaphorin 3E [Homo sapiens] 277 3e-74
gi|5454048 semaphorin 3C [Homo sapiens] 272 1e-72
gi|188497703 semaphorin 3F [Homo sapiens] 269 1e-71
gi|214010220 semaphorin 4D isoform 2 [Homo sapiens] 268 3e-71
gi|214010218 semaphorin 4D isoform 1 [Homo sapiens] 268 3e-71
gi|157388902 semaphorin 4C [Homo sapiens] 254 3e-67
gi|9910362 semaphorin sem2 [Homo sapiens] 251 2e-66
gi|21361914 semaphorin B [Homo sapiens] 244 3e-64
gi|39777610 semaphorin 4B precursor [Homo sapiens] 243 5e-64
gi|39777608 semaphorin 4B precursor [Homo sapiens] 243 5e-64
gi|19923279 semaphorin W [Homo sapiens] 231 3e-60
gi|28872814 semaphorin 4G [Homo sapiens] 228 2e-59
gi|4504237 semaphorin 7A isoform 1 preproprotein [Homo sapiens] 147 4e-35
gi|225637520 semaphorin 7A isoform 2 preproprotein [Homo sapiens] 145 1e-34
gi|225637524 semaphorin 7A isoform 3 [Homo sapiens] 115 3e-25
>gi|11991660 sema domain, transmembrane domain (TM), and cytoplasmic
domain, (semaphorin) 6A [Homo sapiens]
Length = 1030
Score = 2103 bits (5450), Expect = 0.0
Identities = 1030/1030 (100%), Positives = 1030/1030 (100%)
Query: 1 MRSEALLLYFTLLHFAGAGFPEDSEPISISHGNYTKQYPVFVGHKPGRNTTQRHRLDIQM 60
MRSEALLLYFTLLHFAGAGFPEDSEPISISHGNYTKQYPVFVGHKPGRNTTQRHRLDIQM
Sbjct: 1 MRSEALLLYFTLLHFAGAGFPEDSEPISISHGNYTKQYPVFVGHKPGRNTTQRHRLDIQM 60
Query: 61 IMIMNGTLYIAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKGKHKDECHNF 120
IMIMNGTLYIAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKGKHKDECHNF
Sbjct: 61 IMIMNGTLYIAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKGKHKDECHNF 120
Query: 121 IKVLLKKNDDALFVCGTNAFNPSCRNYKMDTLEPFGDEFSGMARCPYDAKHANVALFADG 180
IKVLLKKNDDALFVCGTNAFNPSCRNYKMDTLEPFGDEFSGMARCPYDAKHANVALFADG
Sbjct: 121 IKVLLKKNDDALFVCGTNAFNPSCRNYKMDTLEPFGDEFSGMARCPYDAKHANVALFADG 180
Query: 181 KLYSATVTDFLAIDAVIYRSLGESPTLRTVKHDSKWLKEPYFVQAVDYGDYIYFFFREIA 240
KLYSATVTDFLAIDAVIYRSLGESPTLRTVKHDSKWLKEPYFVQAVDYGDYIYFFFREIA
Sbjct: 181 KLYSATVTDFLAIDAVIYRSLGESPTLRTVKHDSKWLKEPYFVQAVDYGDYIYFFFREIA 240
Query: 241 VEYNTMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNILQAVT 300
VEYNTMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNILQAVT
Sbjct: 241 VEYNTMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNILQAVT 300
Query: 301 DVIRINGRDVVLATFSTPYNSIPGSAVCAYDMLDIASVFTGRFKEQKSPDSTWTPVPDER 360
DVIRINGRDVVLATFSTPYNSIPGSAVCAYDMLDIASVFTGRFKEQKSPDSTWTPVPDER
Sbjct: 301 DVIRINGRDVVLATFSTPYNSIPGSAVCAYDMLDIASVFTGRFKEQKSPDSTWTPVPDER 360
Query: 361 VPKPRPGCCAGSSSLERYATSNEFPDDTLNFIKTHPLMDEAVPSIFNRPWFLRTMVRYRL 420
VPKPRPGCCAGSSSLERYATSNEFPDDTLNFIKTHPLMDEAVPSIFNRPWFLRTMVRYRL
Sbjct: 361 VPKPRPGCCAGSSSLERYATSNEFPDDTLNFIKTHPLMDEAVPSIFNRPWFLRTMVRYRL 420
Query: 421 TKIAVDTAAGPYQNHTVVFLGSEKGIILKFLARIGNSGFLNDSLFLEEMSVYNSEKCSYD 480
TKIAVDTAAGPYQNHTVVFLGSEKGIILKFLARIGNSGFLNDSLFLEEMSVYNSEKCSYD
Sbjct: 421 TKIAVDTAAGPYQNHTVVFLGSEKGIILKFLARIGNSGFLNDSLFLEEMSVYNSEKCSYD 480
Query: 481 GVEDKRIMGMQLDRASSSLYVAFSTCVIKVPLGRCERHGKCKKTCIASRDPYCGWIKEGG 540
GVEDKRIMGMQLDRASSSLYVAFSTCVIKVPLGRCERHGKCKKTCIASRDPYCGWIKEGG
Sbjct: 481 GVEDKRIMGMQLDRASSSLYVAFSTCVIKVPLGRCERHGKCKKTCIASRDPYCGWIKEGG 540
Query: 541 ACSHLSPNSRLTFEQDIERGNTDGLGDCHNSFVALNGHSSSLLPSTTTSDSTAQEGYESR 600
ACSHLSPNSRLTFEQDIERGNTDGLGDCHNSFVALNGHSSSLLPSTTTSDSTAQEGYESR
Sbjct: 541 ACSHLSPNSRLTFEQDIERGNTDGLGDCHNSFVALNGHSSSLLPSTTTSDSTAQEGYESR 600
Query: 601 GGMLDWKHLLDSPDSTDPLGAVSSHNHQDKKGVIRESYLKGHDQLVPVTLLAIAVILAFV 660
GGMLDWKHLLDSPDSTDPLGAVSSHNHQDKKGVIRESYLKGHDQLVPVTLLAIAVILAFV
Sbjct: 601 GGMLDWKHLLDSPDSTDPLGAVSSHNHQDKKGVIRESYLKGHDQLVPVTLLAIAVILAFV 660
Query: 661 MGAVFSGITVYCVCDHRRKDVAVVQRKEKELTHSRRGSMSSVTKLSGLFGDTQSKDPKPE 720
MGAVFSGITVYCVCDHRRKDVAVVQRKEKELTHSRRGSMSSVTKLSGLFGDTQSKDPKPE
Sbjct: 661 MGAVFSGITVYCVCDHRRKDVAVVQRKEKELTHSRRGSMSSVTKLSGLFGDTQSKDPKPE 720
Query: 721 AILTPLMHNGKLATPGNTAKMLIKADQHHLDLTALPTPESTPTLQQKRKPSRGSREWERN 780
AILTPLMHNGKLATPGNTAKMLIKADQHHLDLTALPTPESTPTLQQKRKPSRGSREWERN
Sbjct: 721 AILTPLMHNGKLATPGNTAKMLIKADQHHLDLTALPTPESTPTLQQKRKPSRGSREWERN 780
Query: 781 QNLINACTKDMPPMGSPVIPTDLPLRASPSHIPSVVVLPITQQGYQHEYVDQPKMSEVAQ 840
QNLINACTKDMPPMGSPVIPTDLPLRASPSHIPSVVVLPITQQGYQHEYVDQPKMSEVAQ
Sbjct: 781 QNLINACTKDMPPMGSPVIPTDLPLRASPSHIPSVVVLPITQQGYQHEYVDQPKMSEVAQ 840
Query: 841 MALEDQAATLEYKTIKEHLSSKSPNHGVNLVENLDSLPPKVPQREASLGPPGASLSQTGL 900
MALEDQAATLEYKTIKEHLSSKSPNHGVNLVENLDSLPPKVPQREASLGPPGASLSQTGL
Sbjct: 841 MALEDQAATLEYKTIKEHLSSKSPNHGVNLVENLDSLPPKVPQREASLGPPGASLSQTGL 900
Query: 901 SKRLEMHHSSSYGVDYKRSYPTNSLTRSHQATTLKRNNTNSSNSSHLSRNQSFGRGDNPP 960
SKRLEMHHSSSYGVDYKRSYPTNSLTRSHQATTLKRNNTNSSNSSHLSRNQSFGRGDNPP
Sbjct: 901 SKRLEMHHSSSYGVDYKRSYPTNSLTRSHQATTLKRNNTNSSNSSHLSRNQSFGRGDNPP 960
Query: 961 PAPQRVDSIQVHSSQPSGQAVTVSRQPSLNAYNSLTRSGLKRTPSLKPDVPPKPSFAPLS 1020
PAPQRVDSIQVHSSQPSGQAVTVSRQPSLNAYNSLTRSGLKRTPSLKPDVPPKPSFAPLS
Sbjct: 961 PAPQRVDSIQVHSSQPSGQAVTVSRQPSLNAYNSLTRSGLKRTPSLKPDVPPKPSFAPLS 1020
Query: 1021 TSMKPNDACT 1030
TSMKPNDACT
Sbjct: 1021 TSMKPNDACT 1030
>gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens]
Length = 1073
Score = 883 bits (2282), Expect = 0.0
Identities = 500/1086 (46%), Positives = 664/1086 (61%), Gaps = 91/1086 (8%)
Query: 5 ALLLYFTLLHFAGAGFPEDSEPISISHGNYTKQYPVFVGHKPGRNTTQRHRLDIQMIMIM 64
A +L + FPED EP++ +Y++QYPVF G +P N +Q HRLD Q+++ +
Sbjct: 8 AYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRG-RPSGNESQ-HRLDFQLMLKI 65
Query: 65 NGTLYIAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKGKHKDECHNFIKVL 124
TLYIA RD +YTV+++ E+ +KKLTW+SRQ D + C MKGKHKDECHNFIKV
Sbjct: 66 RDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHNFIKVF 125
Query: 125 LKKNDDALFVCGTNAFNPSCRNYKMDTLEPFGDEFSGMARCPYDAKHANVALFADGKLYS 184
+ +ND+ +FVCGTNAFNP CR Y++ TLE G+E SG+ARCP+DA+ NVALFADGKLYS
Sbjct: 126 VPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFADGKLYS 185
Query: 185 ATVTDFLAIDAVIYRSLGESPTLRTVKHDSKWLKEPYFVQAVDYGDYIYFFFREIAVEYN 244
ATV DFLA DAVIYRS+G+ LRT+K+DSKW+KEP+F+ A++YG+Y+YFFFREIAVE+N
Sbjct: 186 ATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIAVEHN 245
Query: 245 TMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNILQAVTDVIR 304
+GK V+ RVA++CKNDMGGSQRVLEK WTSFLKARLNCSVPGDS FYF++LQ++TD+I+
Sbjct: 246 NLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDIIQ 305
Query: 305 INGRDVVLATFSTPYNSIPGSAVCAYDMLDIASVFTGRFKEQKSPDSTWTPVPDERVPKP 364
ING V+ F+T NSIPGSAVCA+ M DI VF GRFKEQK+PDS WT VP+++VPKP
Sbjct: 306 INGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKP 365
Query: 365 RPGCCAGSSSLERYATSNEFPDDTLNFIKTHPLMDEAVPSIFNRPWFLRTMVRYRLTKIA 424
RPGCCA E Y TS +FPD+TL+FIK+HPLMD AVP I + PWF +T VRYRLT I+
Sbjct: 366 RPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAIS 425
Query: 425 VDTAAGPYQNHTVVFLGSEKGIILKFLARIGNSGFLNDSLFLEEMSVYNSEKCSYDGVED 484
VD +AGPYQN+TV+F+GSE G++LK LA+ LNDS+ LEE+ YN KCS + ED
Sbjct: 426 VDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFS-LNDSVLLEEIEAYNHAKCSAENEED 484
Query: 485 KRIMGMQLDRASSSLYVAFSTCVIKVPLGRCERHGKCKKTCIASRDPYCGWIKEGGACSH 544
K+++ +QLD+ +LYVAFS+C+I++PL RCER+G CKK+CIASRDPYCGW+ +G +C
Sbjct: 485 KKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQG-SCGR 543
Query: 545 LSPNSRLT-FEQDIERGNTDGLGDCHNSFVA-------LNGHSSSLLPSTTTSDSTAQEG 596
++P +EQD E GNT LGDCH + G +S + +++S +T
Sbjct: 544 VTPGMLAEGYEQDTEFGNTAHLGDCHEILPTSTTPDYKIFGGPTSDMEVSSSSVTTMASI 603
Query: 597 YESRGGMLD-WKHLLDSP------------DSTDPLGAVSSHNHQDKKGVIRESYLKGHD 643
E ++D W+ L S D TDPL + KGV E +
Sbjct: 604 PEITPKVIDTWRPKLTSSRKFVVQDDPNTSDFTDPLSGIP-------KGVRWEVQSGESN 656
Query: 644 QLVPVTLLAIAVILAFVMGAVFSGITVYCVCD-HRRKDVAVVQRKEKELTHSRRGSMSSV 702
Q+V + +L V AFV+GA +G+ VYC D RK+ + K+ E S S S
Sbjct: 657 QMVHMNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKI--HKDAESAQSCTDSSGSF 714
Query: 703 TKLSGLFG----DTQSKDPKPEAILTPLMHNGKLATPGNTAKMLIKADQHHLDLTALPTP 758
KL+GLF + Q P+ L +L G+T M++ +L ALPTP
Sbjct: 715 AKLNGLFDSPVKEYQQNIDSPKLYSNLLTSRKELPPNGDTKSMVMDHRGQPPELAALPTP 774
Query: 759 ESTPTLQQKRKPSRGSREWERNQNLINACTKDMPPMGSPVIPTDLPLRASPSHIPSVVVL 818
ESTP L QK + S + + + A K+ P P PL S HIPS +VL
Sbjct: 775 ESTPVLHQKTLQAMKSHSEKAHGH--GASRKETPQFFPSSPPPHSPL--SHGHIPSAIVL 830
Query: 819 PITQQGYQHEY--------------VDQP----------KMSEVAQMALEDQAATL---- 850
P Y + +D P + S ++ L D L
Sbjct: 831 PNATHDYNTSFSNSNAHKAEKKLQNIDHPLTKSSSKRDHRRSVDSRNTLNDLLKHLNDPN 890
Query: 851 -EYKTIKEHLSSKSPNHGVNLVENLDSLPPKVPQREASLGPPGASLSQTGLSKRLEMHHS 909
K I + N ++ + ++ +PPKVP REASL P ++L + +KR+++ +
Sbjct: 891 SNPKAIMGDIQMAHQNLMLDPMGSMSEVPPKVPNREASLYSPPSTLPRNSPTKRVDVPTT 950
Query: 910 SSY---GVDYKRSYPTNSLTRSHQATTLKRNNTNSSNSSHLSRNQSFGRGD-NPPPAPQR 965
++ +R Y NS R H + + + N NS N LSR S RG P P +
Sbjct: 951 PGVPMTSLERQRGYHKNSSQR-HSISAMPK-NLNSPNGVLLSRQPSMNRGGYMPTPTGAK 1008
Query: 966 VDSIQVHSSQPSGQAVTVSRQPSLNAYNSLT------RSGLKRTPSLKPDVPPKPSFAPL 1019
VD IQ G V+V QPSL+ +S T R+GLKRTPSLKPDVPPKPSF P
Sbjct: 1009 VDYIQ-------GTPVSVHLQPSLSRQSSYTSNGTLPRTGLKRTPSLKPDVPPKPSFVPQ 1061
Query: 1020 STSMKP 1025
+ S++P
Sbjct: 1062 TPSVRP 1067
>gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens]
Length = 1017
Score = 877 bits (2267), Expect = 0.0
Identities = 495/1066 (46%), Positives = 652/1066 (61%), Gaps = 107/1066 (10%)
Query: 5 ALLLYFTLLHFAGAGFPEDSEPISISHGNYTKQYPVFVGHKPGRNTTQRHRLDIQMIMIM 64
A +L + FPED EP++ +Y++QYPVF G +P N +Q HRLD Q+++ +
Sbjct: 8 AYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRG-RPSGNESQ-HRLDFQLMLKI 65
Query: 65 NGTLYIAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKGKHKDECHNFIKVL 124
TLYIA RD +YTV+++ E+ +KKLTW+SRQ D + C MKGKHKDECHNFIKV
Sbjct: 66 RDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHNFIKVF 125
Query: 125 LKKNDDALFVCGTNAFNPSCRNYKMDTLEPFGDEFSGMARCPYDAKHANVALFADGKLYS 184
+ +ND+ +FVCGTNAFNP CR Y++ TLE G+E SG+ARCP+DA+ NVALFADGKLYS
Sbjct: 126 VPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFADGKLYS 185
Query: 185 ATVTDFLAIDAVIYRSLGESPTLRTVKHDSKWLKEPYFVQAVDYGDYIYFFFREIAVEYN 244
ATV DFLA DAVIYRS+G+ LRT+K+DSKW+KEP+F+ A++YG+Y+YFFFREIAVE+N
Sbjct: 186 ATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIAVEHN 245
Query: 245 TMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNILQAVTDVIR 304
+GK V+ RVA++CKNDMGGSQRVLEK WTSFLKARLNCSVPGDS FYF++LQ++TD+I+
Sbjct: 246 NLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDIIQ 305
Query: 305 INGRDVVLATFSTPYNSIPGSAVCAYDMLDIASVFTGRFKEQKSPDSTWTPVPDERVPKP 364
ING V+ F+T NSIPGSAVCA+ M DI VF GRFKEQK+PDS WT VP+++VPKP
Sbjct: 306 INGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKP 365
Query: 365 RPGCCAGSSSLERYATSNEFPDDTLNFIKTHPLMDEAVPSIFNRPWFLRTMVRYRLTKIA 424
RPGCCA E Y TS +FPD+TL+FIK+HPLMD AVP I + PWF +T VRYRLT I+
Sbjct: 366 RPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAIS 425
Query: 425 VDTAAGPYQNHTVVFLGSEKGIILKFLARIGNSGFLNDSLFLEEMSVYNSEKCSYDGVED 484
VD +AGPYQN+TV+F+GSE G++LK LA+ LNDS+ LEE+ YN KCS + ED
Sbjct: 426 VDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFS-LNDSVLLEEIEAYNHAKCSAENEED 484
Query: 485 KRIMGMQLDRASSSLYVAFSTCVIKVPLGRCERHGKCKKTCIASRDPYCGWIKEGGACSH 544
K+++ +QLD+ +LYVAFS+C+I++PL RCER+G CKK+CIASRDPYCGW+ + G+C
Sbjct: 485 KKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQ-GSCGR 543
Query: 545 LSPNSRLT-FEQDIERGNTDGLGDCHNSFVALNGHSSSLLPSTTTSDSTAQEGYESRGGM 603
++P +EQD E GNT LGDCH +LP++TT D Y+ GG
Sbjct: 544 VTPGMLAEGYEQDTEFGNTAHLGDCH-----------EILPTSTTPD------YKIFGG- 585
Query: 604 LDWKHLLDSPDSTDPLGAVSSHNHQDKKGVIRESYLKGHDQLVPVTLLAIAVILAFVMGA 663
P S GV E +Q+V + +L V AFV+GA
Sbjct: 586 ---------PTS----------------GVRWEVQSGESNQMVHMNVLITCVFAAFVLGA 620
Query: 664 VFSGITVYCVCD-HRRKDVAVVQRKEKELTHSRRGSMSSVTKLSGLFG----DTQSKDPK 718
+G+ VYC D RK+ + K+ E S S S KL+GLF + Q
Sbjct: 621 FIAGVAVYCYRDMFVRKNRKI--HKDAESAQSCTDSSGSFAKLNGLFDSPVKEYQQNIDS 678
Query: 719 PEAILTPLMHNGKLATPGNTAKMLIKADQHHLDLTALPTPESTPTLQQKRKPSRGSREWE 778
P+ L +L G+T M++ +L ALPTPESTP L QK + S +
Sbjct: 679 PKLYSNLLTSRKELPPNGDTKSMVMDHRGQPPELAALPTPESTPVLHQKTLQAMKSHSEK 738
Query: 779 RNQNLINACTKDMPPMGSPVIPTDLPLRASPSHIPSVVVLPITQQGYQHEY--------- 829
+ + A K+ P P PL S HIPS +VLP Y +
Sbjct: 739 AHGH--GASRKETPQFFPSSPPPHSPL--SHGHIPSAIVLPNATHDYNTSFSNSNAHKAE 794
Query: 830 -----VDQP----------KMSEVAQMALEDQAATL-----EYKTIKEHLSSKSPNHGVN 869
+D P + S ++ L D L K I + N ++
Sbjct: 795 KKLQNIDHPLTKSSSKRDHRRSVDSRNTLNDLLKHLNDPNSNPKAIMGDIQMAHQNLMLD 854
Query: 870 LVENLDSLPPKVPQREASLGPPGASLSQTGLSKRLEMHHSSSY---GVDYKRSYPTNSLT 926
+ ++ +PPKVP REASL P ++L + +KR+++ + ++ +R Y NS
Sbjct: 855 PMGSMSEVPPKVPNREASLYSPPSTLPRNSPTKRVDVPTTPGVPMTSLERQRGYHKNSSQ 914
Query: 927 RSHQATTLKRNNTNSSNSSHLSRNQSFGRGD-NPPPAPQRVDSIQVHSSQPSGQAVTVSR 985
R H + + + N NS N LSR S RG P P +VD IQ G V+V
Sbjct: 915 R-HSISAMPK-NLNSPNGVLLSRQPSMNRGGYMPTPTGAKVDYIQ-------GTPVSVHL 965
Query: 986 QPSLNAYNSLT------RSGLKRTPSLKPDVPPKPSFAPLSTSMKP 1025
QPSL+ +S T R+GLKRTPSLKPDVPPKPSF P + S++P
Sbjct: 966 QPSLSRQSSYTSNGTLPRTGLKRTPSLKPDVPPKPSFVPQTPSVRP 1011
>gi|24234729 semaphorin 6D isoform 1 precursor [Homo sapiens]
Length = 1011
Score = 858 bits (2218), Expect = 0.0
Identities = 486/1065 (45%), Positives = 641/1065 (60%), Gaps = 111/1065 (10%)
Query: 5 ALLLYFTLLHFAGAGFPEDSEPISISHGNYTKQYPVFVGHKPGRNTTQRHRLDIQMIMIM 64
A +L + FPED EP++ +Y++QYPVF G +P N +Q HRLD Q+++ +
Sbjct: 8 AYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRG-RPSGNESQ-HRLDFQLMLKI 65
Query: 65 NGTLYIAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKGKHKDECHNFIKVL 124
TLYIA RD +YTV+++ E+ +KKLTW+SRQ D + C MKGKHKDECHNFIKV
Sbjct: 66 RDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHNFIKVF 125
Query: 125 LKKNDDALFVCGTNAFNPSCRNYKMDTLEPFGDEFSGMARCPYDAKHANVALFADGKLYS 184
+ +ND+ +FVCGTNAFNP CR Y++ TLE G+E SG+ARCP+DA+ NVALFADGKLYS
Sbjct: 126 VPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFADGKLYS 185
Query: 185 ATVTDFLAIDAVIYRSLGESPTLRTVKHDSKWLKEPYFVQAVDYGDYIYFFFREIAVEYN 244
ATV DFLA DAVIYRS+G+ LRT+K+DSKW+KEP+F+ A++YG+Y+YFFFREIAVE+N
Sbjct: 186 ATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIAVEHN 245
Query: 245 TMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNILQAVTDVIR 304
+GK V+ RVA++CKNDMGGSQRVLEK WTSFLKARLNCSVPGDS FYF++LQ++TD+I+
Sbjct: 246 NLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDIIQ 305
Query: 305 INGRDVVLATFSTPYNSIPGSAVCAYDMLDIASVFTGRFKEQKSPDSTWTPVPDERVPKP 364
ING V+ F+T NSIPGSAVCA+ M DI VF GRFKEQK+PDS WT VP+++VPKP
Sbjct: 306 INGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKP 365
Query: 365 RPGCCAGSSSLERYATSNEFPDDTLNFIKTHPLMDEAVPSIFNRPWFLRTMVRYRLTKIA 424
RPGCCA E Y TS +FPD+TL+FIK+HPLMD AVP I + PWF +T VRYRLT I+
Sbjct: 366 RPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAIS 425
Query: 425 VDTAAGPYQNHTVVFLGSEKGIILKFLARIGNSGFLNDSLFLEEMSVYNSEKCSYDGVED 484
VD +AGPYQN+TV+F+GSE G++LK LA+ LNDS+ LEE+ YN KCS + ED
Sbjct: 426 VDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFS-LNDSVLLEEIEAYNHAKCSAENEED 484
Query: 485 KRIMGMQLDRASSSLYVAFSTCVIKVPLGRCERHGKCKKTCIASRDPYCGWIKEGGACSH 544
K+++ +QLD+ +LYVAFS+C+I++PL RCER+G CKK+CIASRDPYCGW+ +G +C
Sbjct: 485 KKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQG-SCGR 543
Query: 545 LSPNSRLTFEQDIERGNTDGLGDCHNSFVALNGHSSSLLPSTTTSDSTAQEGYESRGGML 604
++P L E F A + HS+ EGYE
Sbjct: 544 VTPGMLLLTED----------------FFAFHNHSA--------------EGYEQDTEFG 573
Query: 605 DWKHLLDSPDSTDPLGAVSSHNHQDKKGVIRESYLKGHDQLVPVTLLAIAVILAFVMGAV 664
+ HL D GV E +Q+V + +L V AFV+GA
Sbjct: 574 NTAHLGDC------------------HGVRWEVQSGESNQMVHMNVLITCVFAAFVLGAF 615
Query: 665 FSGITVYCVCD-HRRKDVAVVQRKEKELTHSRRGSMSSVTKLSGLFG----DTQSKDPKP 719
+G+ VYC D RK+ + K+ E S S S KL+GLF + Q P
Sbjct: 616 IAGVAVYCYRDMFVRKNRKI--HKDAESAQSCTDSSGSFAKLNGLFDSPVKEYQQNIDSP 673
Query: 720 EAILTPLMHNGKLATPGNTAKMLIKADQHHLDLTALPTPESTPTLQQKRKPSRGSREWER 779
+ L +L G+T M++ +L ALPTPESTP L QK + S +
Sbjct: 674 KLYSNLLTSRKELPPNGDTKSMVMDHRGQPPELAALPTPESTPVLHQKTLQAMKSHSEKA 733
Query: 780 NQNLINACTKDMPPMGSPVIPTDLPLRASPSHIPSVVVLPITQQGYQHEY---------- 829
+ + A K+ P P PL S HIPS +VLP Y +
Sbjct: 734 HGH--GASRKETPQFFPSSPPPHSPL--SHGHIPSAIVLPNATHDYNTSFSNSNAHKAEK 789
Query: 830 ----VDQP----------KMSEVAQMALEDQAATL-----EYKTIKEHLSSKSPNHGVNL 870
+D P + S ++ L D L K I + N ++
Sbjct: 790 KLQNIDHPLTKSSSKRDHRRSVDSRNTLNDLLKHLNDPNSNPKAIMGDIQMAHQNLMLDP 849
Query: 871 VENLDSLPPKVPQREASLGPPGASLSQTGLSKRLEMHHSSSY---GVDYKRSYPTNSLTR 927
+ ++ +PPKVP REASL P ++L + +KR+++ + ++ +R Y NS R
Sbjct: 850 MGSMSEVPPKVPNREASLYSPPSTLPRNSPTKRVDVPTTPGVPMTSLERQRGYHKNSSQR 909
Query: 928 SHQATTLKRNNTNSSNSSHLSRNQSFGRGD-NPPPAPQRVDSIQVHSSQPSGQAVTVSRQ 986
H + + + N NS N LSR S RG P P +VD IQ G V+V Q
Sbjct: 910 -HSISAMPK-NLNSPNGVLLSRQPSMNRGGYMPTPTGAKVDYIQ-------GTPVSVHLQ 960
Query: 987 PSLNAYNSLT------RSGLKRTPSLKPDVPPKPSFAPLSTSMKP 1025
PSL+ +S T R+GLKRTPSLKPDVPPKPSF P + S++P
Sbjct: 961 PSLSRQSSYTSNGTLPRTGLKRTPSLKPDVPPKPSFVPQTPSVRP 1005
>gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens]
Length = 998
Score = 844 bits (2181), Expect = 0.0
Identities = 481/1065 (45%), Positives = 634/1065 (59%), Gaps = 124/1065 (11%)
Query: 5 ALLLYFTLLHFAGAGFPEDSEPISISHGNYTKQYPVFVGHKPGRNTTQRHRLDIQMIMIM 64
A +L + FPED EP++ +Y++QYPVF G +P N +Q HRLD Q+++ +
Sbjct: 8 AYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRG-RPSGNESQ-HRLDFQLMLKI 65
Query: 65 NGTLYIAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKGKHKDECHNFIKVL 124
TLYIA RD +YTV+++ E+ +KKLTW+SRQ D + C MKGKHKDECHNFIKV
Sbjct: 66 RDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHNFIKVF 125
Query: 125 LKKNDDALFVCGTNAFNPSCRNYKMDTLEPFGDEFSGMARCPYDAKHANVALFADGKLYS 184
+ +ND+ +FVCGTNAFNP CR Y++ TLE G+E SG+ARCP+DA+ NVALFADGKLYS
Sbjct: 126 VPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFADGKLYS 185
Query: 185 ATVTDFLAIDAVIYRSLGESPTLRTVKHDSKWLKEPYFVQAVDYGDYIYFFFREIAVEYN 244
ATV DFLA DAVIYRS+G+ LRT+K+DSKW+KEP+F+ A++YG+Y+YFFFREIAVE+N
Sbjct: 186 ATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIAVEHN 245
Query: 245 TMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNILQAVTDVIR 304
+GK V+ RVA++CKNDMGGSQRVLEK WTSFLKARLNCSVPGDS FYF++LQ++TD+I+
Sbjct: 246 NLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDIIQ 305
Query: 305 INGRDVVLATFSTPYNSIPGSAVCAYDMLDIASVFTGRFKEQKSPDSTWTPVPDERVPKP 364
ING V+ F+T NSIPGSAVCA+ M DI VF GRFKEQK+PDS WT VP+++VPKP
Sbjct: 306 INGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKP 365
Query: 365 RPGCCAGSSSLERYATSNEFPDDTLNFIKTHPLMDEAVPSIFNRPWFLRTMVRYRLTKIA 424
RPGCCA E Y TS +FPD+TL+FIK+HPLMD AVP I + PWF +T VRYRLT I+
Sbjct: 366 RPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAIS 425
Query: 425 VDTAAGPYQNHTVVFLGSEKGIILKFLARIGNSGFLNDSLFLEEMSVYNSEKCSYDGVED 484
VD +AGPYQN+TV+F+GSE G++LK LA+ LNDS+ LEE+ YN KCS + ED
Sbjct: 426 VDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFS-LNDSVLLEEIEAYNHAKCSAENEED 484
Query: 485 KRIMGMQLDRASSSLYVAFSTCVIKVPLGRCERHGKCKKTCIASRDPYCGWIKEGGACSH 544
K+++ +QLD+ +LYVAFS+C+I++PL RCER+G CKK+CIASRDPYCGW+ +G +C
Sbjct: 485 KKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQG-SCGR 543
Query: 545 LSPNSRLTFEQDIERGNTDGLGDCHNSFVALNGHSSSLLPSTTTSDSTAQEGYESRGGML 604
+ T G+ EGYE
Sbjct: 544 V----------------TPGM---------------------------LAEGYEQDTEFG 560
Query: 605 DWKHLLDSPDSTDPLGAVSSHNHQDKKGVIRESYLKGHDQLVPVTLLAIAVILAFVMGAV 664
+ HL D GV E +Q+V + +L V AFV+GA
Sbjct: 561 NTAHLGDC------------------HGVRWEVQSGESNQMVHMNVLITCVFAAFVLGAF 602
Query: 665 FSGITVYCVCD-HRRKDVAVVQRKEKELTHSRRGSMSSVTKLSGLFG----DTQSKDPKP 719
+G+ VYC D RK+ + K+ E S S S KL+GLF + Q P
Sbjct: 603 IAGVAVYCYRDMFVRKNRKI--HKDAESAQSCTDSSGSFAKLNGLFDSPVKEYQQNIDSP 660
Query: 720 EAILTPLMHNGKLATPGNTAKMLIKADQHHLDLTALPTPESTPTLQQKRKPSRGSREWER 779
+ L +L G+T M++ +L ALPTPESTP L QK + S +
Sbjct: 661 KLYSNLLTSRKELPPNGDTKSMVMDHRGQPPELAALPTPESTPVLHQKTLQAMKSHSEKA 720
Query: 780 NQNLINACTKDMPPMGSPVIPTDLPLRASPSHIPSVVVLPITQQGYQHEY---------- 829
+ + A K+ P P PL S HIPS +VLP Y +
Sbjct: 721 HGH--GASRKETPQFFPSSPPPHSPL--SHGHIPSAIVLPNATHDYNTSFSNSNAHKAEK 776
Query: 830 ----VDQP----------KMSEVAQMALEDQAATL-----EYKTIKEHLSSKSPNHGVNL 870
+D P + S ++ L D L K I + N ++
Sbjct: 777 KLQNIDHPLTKSSSKRDHRRSVDSRNTLNDLLKHLNDPNSNPKAIMGDIQMAHQNLMLDP 836
Query: 871 VENLDSLPPKVPQREASLGPPGASLSQTGLSKRLEMHHSSSY---GVDYKRSYPTNSLTR 927
+ ++ +PPKVP REASL P ++L + +KR+++ + ++ +R Y NS R
Sbjct: 837 MGSMSEVPPKVPNREASLYSPPSTLPRNSPTKRVDVPTTPGVPMTSLERQRGYHKNSSQR 896
Query: 928 SHQATTLKRNNTNSSNSSHLSRNQSFGRGD-NPPPAPQRVDSIQVHSSQPSGQAVTVSRQ 986
H + + + N NS N LSR S RG P P +VD IQ G V+V Q
Sbjct: 897 -HSISAMPK-NLNSPNGVLLSRQPSMNRGGYMPTPTGAKVDYIQ-------GTPVSVHLQ 947
Query: 987 PSLNAYNSLT------RSGLKRTPSLKPDVPPKPSFAPLSTSMKP 1025
PSL+ +S T R+GLKRTPSLKPDVPPKPSF P + S++P
Sbjct: 948 PSLSRQSSYTSNGTLPRTGLKRTPSLKPDVPPKPSFVPQTPSVRP 992
>gi|24234744 semaphorin 6D isoform 5 precursor [Homo sapiens]
Length = 597
Score = 738 bits (1906), Expect = 0.0
Identities = 346/588 (58%), Positives = 450/588 (76%), Gaps = 5/588 (0%)
Query: 5 ALLLYFTLLHFAGAGFPEDSEPISISHGNYTKQYPVFVGHKPGRNTTQRHRLDIQMIMIM 64
A +L + FPED EP++ +Y++QYPVF G +P N +Q HRLD Q+++ +
Sbjct: 8 AYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRG-RPSGNESQ-HRLDFQLMLKI 65
Query: 65 NGTLYIAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKGKHKDECHNFIKVL 124
TLYIA RD +YTV+++ E+ +KKLTW+SRQ D + C MKGKHKDECHNFIKV
Sbjct: 66 RDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHNFIKVF 125
Query: 125 LKKNDDALFVCGTNAFNPSCRNYKMDTLEPFGDEFSGMARCPYDAKHANVALFADGKLYS 184
+ +ND+ +FVCGTNAFNP CR Y++ TLE G+E SG+ARCP+DA+ NVALFADGKLYS
Sbjct: 126 VPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFADGKLYS 185
Query: 185 ATVTDFLAIDAVIYRSLGESPTLRTVKHDSKWLKEPYFVQAVDYGDYIYFFFREIAVEYN 244
ATV DFLA DAVIYRS+G+ LRT+K+DSKW+KEP+F+ A++YG+Y+YFFFREIAVE+N
Sbjct: 186 ATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIAVEHN 245
Query: 245 TMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNILQAVTDVIR 304
+GK V+ RVA++CKNDMGGSQRVLEK WTSFLKARLNCSVPGDS FYF++LQ++TD+I+
Sbjct: 246 NLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDIIQ 305
Query: 305 INGRDVVLATFSTPYNSIPGSAVCAYDMLDIASVFTGRFKEQKSPDSTWTPVPDERVPKP 364
ING V+ F+T NSIPGSAVCA+ M DI VF GRFKEQK+PDS WT VP+++VPKP
Sbjct: 306 INGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKP 365
Query: 365 RPGCCAGSSSLERYATSNEFPDDTLNFIKTHPLMDEAVPSIFNRPWFLRTMVRYRLTKIA 424
RPGCCA E Y TS +FPD+TL+FIK+HPLMD AVP I + PWF +T VRYRLT I+
Sbjct: 366 RPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAIS 425
Query: 425 VDTAAGPYQNHTVVFLGSEKGIILKFLARIGNSGFLNDSLFLEEMSVYNSEKCSYDGVED 484
VD +AGPYQN+TV+F+GSE G++LK LA+ LNDS+ LEE+ YN KCS + ED
Sbjct: 426 VDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFS-LNDSVLLEEIEAYNHAKCSAENEED 484
Query: 485 KRIMGMQLDRASSSLYVAFSTCVIKVPLGRCERHGKCKKTCIASRDPYCGWIKEGGACSH 544
K+++ +QLD+ +LYVAFS+C+I++PL RCER+G CKK+CIASRDPYCGW+ + G+C
Sbjct: 485 KKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQ-GSCGR 543
Query: 545 LSPNSRLT-FEQDIERGNTDGLGDCHNSFVALNGHSSSLLPSTTTSDS 591
++P +EQD E GNT LGDCH+ V+ + ++ + ++ +S
Sbjct: 544 VTPGMLAEGYEQDTEFGNTAHLGDCHDMEVSSSSVTTMVYDGKSSLES 591
>gi|19718780 semaphorin 6B precursor [Homo sapiens]
Length = 888
Score = 733 bits (1892), Expect = 0.0
Identities = 393/809 (48%), Positives = 512/809 (63%), Gaps = 103/809 (12%)
Query: 5 ALLLYFTLLHFAGAGFPEDSEPISISHGNYTKQYPVFVGHKPGRNTTQRHR--LDIQMIM 62
ALLL LL A FPE+ P+S++ +Y YPVFVG PGR T L+IQ ++
Sbjct: 12 ALLLLLLLLGGAHGLFPEEPPPLSVAPRDYLNHYPVFVGSGPGRLTPAEGADDLNIQRVL 71
Query: 63 IMNGTLYIAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKGKHKDECHNFIK 122
+N TL+I RD++Y V+++ + E+ +KLTW+S +D++ CRMKGK + EC NF+K
Sbjct: 72 RVNRTLFIGDRDNLYRVELEPPTSTELRYQRKLTWRSNPSDINVCRMKGKQEGECRNFVK 131
Query: 123 VLLKKNDDALFVCGTNAFNPSCRNYKMDTLEPFGDEFSGMARCPYDAKHANVALFADGKL 182
VLL +++ LFVCG+NAFNP C NY +DTL+P GD SGMARCPYD KHANVALF+DG L
Sbjct: 132 VLLLRDESTLFVCGSNAFNPVCANYSIDTLQPVGDNISGMARCPYDPKHANVALFSDGML 191
Query: 183 YSATVTDFLAIDAVIYRSLGESPTLRTVKHDSKWLKEPYFVQAVDYGDYIYFFFREIAVE 242
++ATVTDFLAIDAVIYRSLG+ PTLRTVKHDSKW KEPYFV AV++G ++YFFFREIA+E
Sbjct: 192 FTATVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWFKEPYFVHAVEWGSHVYFFFREIAME 251
Query: 243 YNTMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNILQAVTDV 302
+N + KVV RVA+VCKND+GGS RVLEKQWTSFLKARLNCSVPGDSHFYFN+LQAVT V
Sbjct: 252 FNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSHFYFNVLQAVTGV 311
Query: 303 IRINGRDVVLATFSTPYNSIPGSAVCAYDMLDIASVFTGRFKEQKSPDSTWTPVPDERVP 362
+ + GR VVLA FSTP NSIPGSAVCA+D+ +A+VF GRF+EQKSP+S WTPVP+++VP
Sbjct: 312 VSLGGRPVVLAVFSTPSNSIPGSAVCAFDLTQVAAVFEGRFREQKSPESIWTPVPEDQVP 371
Query: 363 KPRPGCCAGSSSLERYATSNEFPDDTLNFIKTHPLMDEAVPSIFNRPWFLRTMVRYRLTK 422
+PRPGCCA +Y S+ PDD LNF+KTHPLMDEAVPS+ + PW LRT++R++LT+
Sbjct: 372 RPRPGCCAAPGM--QYNASSALPDDILNFVKTHPLMDEAVPSLGHAPWILRTLMRHQLTR 429
Query: 423 IAVDTAAGPYQNHTVVFLGSEKGIILKFLAR--IGNSGFLNDSLFLEEMSVYNSEKCSYD 480
+AVD AGP+ N TVVFLGSE G +LKFL R SG S+FLEE Y ++C
Sbjct: 430 VAVDVGAGPWGNQTVVFLGSEAGTVLKFLVRPNASTSGTSGLSVFLEEFETYRPDRCGRP 489
Query: 481 GVED--KRIMGMQLDRASSSLYVAFSTCVIKVPLGRCERHGKCKKTCIASRDPYCGWIKE 538
G + +R++ ++LD AS L AF CV++VP+ RC+++ C K CI S+DPYCGW +
Sbjct: 490 GGGETGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQQYSGCMKNCIGSQDPYCGWAPD 549
Query: 539 GGACSHLSPNSRLTFEQDIERGNTDGLGDCHNSFVALNGHSSSLLPSTTTSDSTAQEGYE 598
G+C LSP +R FEQD+ +T GLGDC
Sbjct: 550 -GSCIFLSPGTRAAFEQDVSGASTSGLGDC------------------------------ 578
Query: 599 SRGGMLDWKHLLDSPDSTDPLGAVSSHNHQDKKGVIRESYLKGHDQLVPVTLLAIAVILA 658
G + + +D+ G++ + L VT A ++
Sbjct: 579 --------------------TGLLRASLSEDRAGLVSVNLL--------VTSSVAAFVV- 609
Query: 659 FVMGAVFSGITV-YCVCDHRRKDVAVVQRKEKELTHSRRGSMSSVTKLSGLFGDTQSKDP 717
GAV SG +V + V R+++A + KE L H ++ SV++L G+ +++ P
Sbjct: 610 ---GAVVSGFSVGWFVGLRERRELARRKDKEAILAHGAGEAVLSVSRL----GERRAQGP 662
Query: 718 -------------KPEAILTPLMHNGKLATPGNTAKMLIKADQHHLDLTALPTPESTPTL 764
PEA+L PLM NG L++ H LD LPTPE TP L
Sbjct: 663 GGRGGGGGGGAGVPPEALLAPLMQNGW------AKATLLQGGPHDLDSGLLPTPEQTP-L 715
Query: 765 QQKRKP-------SRGSREWERNQNLINA 786
QKR P + G R W+ L+ A
Sbjct: 716 PQKRLPTPHPHPHALGPRAWDHGHPLLPA 744
>gi|24234732 semaphorin 6D isoform 6 precursor [Homo sapiens]
Length = 476
Score = 621 bits (1602), Expect = e-178
Identities = 292/472 (61%), Positives = 368/472 (77%), Gaps = 3/472 (0%)
Query: 5 ALLLYFTLLHFAGAGFPEDSEPISISHGNYTKQYPVFVGHKPGRNTTQRHRLDIQMIMIM 64
A +L + FPED EP++ +Y++QYPVF G +P N +Q HRLD Q+++ +
Sbjct: 8 AYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRG-RPSGNESQ-HRLDFQLMLKI 65
Query: 65 NGTLYIAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKGKHKDECHNFIKVL 124
TLYIA RD +YTV+++ E+ +KKLTW+SRQ D + C MKGKHKDECHNFIKV
Sbjct: 66 RDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHNFIKVF 125
Query: 125 LKKNDDALFVCGTNAFNPSCRNYKMDTLEPFGDEFSGMARCPYDAKHANVALFADGKLYS 184
+ +ND+ +FVCGTNAFNP CR Y++ TLE G+E SG+ARCP+DA+ NVALFADGKLYS
Sbjct: 126 VPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFADGKLYS 185
Query: 185 ATVTDFLAIDAVIYRSLGESPTLRTVKHDSKWLKEPYFVQAVDYGDYIYFFFREIAVEYN 244
ATV DFLA DAVIYRS+G+ LRT+K+DSKW+KEP+F+ A++YG+Y+YFFFREIAVE+N
Sbjct: 186 ATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIAVEHN 245
Query: 245 TMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNILQAVTDVIR 304
+GK V+ RVA++CKNDMGGSQRVLEK WTSFLKARLNCSVPGDS FYF++LQ++TD+I+
Sbjct: 246 NLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDIIQ 305
Query: 305 INGRDVVLATFSTPYNSIPGSAVCAYDMLDIASVFTGRFKEQKSPDSTWTPVPDERVPKP 364
ING V+ F+T NSIPGSAVCA+ M DI VF GRFKEQK+PDS WT VP+++VPKP
Sbjct: 306 INGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKP 365
Query: 365 RPGCCAGSSSLERYATSNEFPDDTLNFIKTHPLMDEAVPSIFNRPWFLRTMVRYRLTKIA 424
RPGCCA E Y TS +FPD+TL+FIK+HPLMD AVP I + PWF +T VRYRLT I+
Sbjct: 366 RPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAIS 425
Query: 425 VDTAAGPYQNHTVVFLGSEKGIILKFLARIGNSGFLNDSLFLEEMSVYNSEK 476
VD +AGPYQN+TV+F+GSE G++LK LA+ LNDS+ LEE+ YN K
Sbjct: 426 VDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFS-LNDSVLLEEIEAYNHAK 476
>gi|16306552 semaphorin Y [Homo sapiens]
Length = 930
Score = 561 bits (1447), Expect = e-160
Identities = 324/789 (41%), Positives = 448/789 (56%), Gaps = 81/789 (10%)
Query: 6 LLLYFTLLHFAGAGFPEDSEPISISHGNYTKQYPVFVGHKPGRNTTQRHRLDIQMIMIMN 65
LLL +L H A FP+D P+ IS T F G + + LD Q + +N
Sbjct: 13 LLLLLSLPH-TQAAFPQDPLPLLISDLQGTSPLSWFRGLEDDAVAAEL-GLDFQRFLTLN 70
Query: 66 GTLYIAARDHIYTVDIDTSHT-EEIYCSKKLTWKSRQADVDTCRMKGKHKDECHNFIKVL 124
TL +AARDH+++ D+ E + +K LTW+S+ DV+ C ++GK DEC+N+I+VL
Sbjct: 71 RTLLVAARDHVFSFDLQAEEEGEGLVPNKYLTWRSQ--DVENCAVRGKLTDECYNYIRVL 128
Query: 125 LKKNDDALFVCGTNAFNPSCRNYKMDTLEPFGDEFSGMARCPYDAKHANVALFADGKLYS 184
+ + L CGTN+F+P CR+Y + +L+ G+E SG ARCP+DA +NVA+FA+G LYS
Sbjct: 129 VPWDSQTLLACGTNSFSPVCRSYGITSLQQEGEELSGQARCPFDATQSNVAIFAEGSLYS 188
Query: 185 ATVTDFLAIDAVIYRSLGESPTLRTVKHDSKWLKEPYFVQAVDYGDYIYFFFREIAVEYN 244
AT DF A DAV+YRSLG P LR+ K+DSKWL+EP+FVQA+++GD++YFFFRE++VE
Sbjct: 189 ATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVQALEHGDHVYFFFREVSVEDA 248
Query: 245 TMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNILQAVTDVIR 304
+G+V F RVA+VCK DMGGS R L++ WTSFLK RLNCSVPGDS FYF++LQA+T +
Sbjct: 249 RLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTFYFDVLQALTGPVN 308
Query: 305 INGRDVVLATFSTPYNSIPGSAVCAYDMLDIASVFTGRFKEQKSPDSTWTPVPDERVPKP 364
++GR + F+T NSIPGSAVCA+ + +I F G+FKEQ+S D WTPV ++RVP P
Sbjct: 309 LHGRSALFGVFTTQTNSIPGSAVCAFYLDEIERGFEGKFKEQRSLDGAWTPVSEDRVPSP 368
Query: 365 RPGCCAGSSSLERYATSNEFPDDTLNFIKTHPLMDEAVPSIFNRPWFLRTMVRYRLTKIA 424
RPG CAG +++S + PDD L FIK HPL+D AVP + ++P L R LT++A
Sbjct: 369 RPGSCAGVGGAALFSSSRDLPDDVLTFIKAHPLLDPAVPPVTHQP-LLTLTSRALLTQVA 427
Query: 425 VDTAAGPYQNHTVVFLGSEKGIILKFLARIGNSGFLNDSLFLEEMSVYNSEKCSYDGVED 484
VD AGP+ N TV+FLGS G +LK L G SG + + LEE+ Y+ +CS
Sbjct: 428 VDGMAGPHSNITVMFLGSNDGTVLKVLTPGGRSGG-PEPILLEEIDAYSPARCSGKRTAQ 486
Query: 485 --KRIMGMQLDRASSSLYVAFSTCVIKVPLGRCERHGKCKKTCIASRDPYCGWIKEGGAC 542
+RI+G++LD L+VAFS C++ +PL RC RHG C+++C+AS+DPYCGW G C
Sbjct: 487 TARRIIGLELDTEGHRLFVAFSGCIVYLPLSRCARHGACQRSCLASQDPYCGWHSSRG-C 545
Query: 543 SHLSPNSRLTFEQDIERGNTDGL--GDCHNSFVALNGHSSSLLPSTTTSDSTAQEGYESR 600
+ + +Q GN + + GDC + +T + Y
Sbjct: 546 VDIRGSGGTDVDQ---AGNQESMEHGDCQDG-------------ATGSQSGPGDSAY--- 586
Query: 601 GGMLDWKHLLDSPDSTDPLGAVSSHNHQDKKGVIRESYLKGHDQLVPVTLLAIAVILAFV 660
GV R+ + VP+ LL +V AF
Sbjct: 587 -------------------------------GVRRDLPPASASRSVPIPLLLASVAAAFA 615
Query: 661 MGAVFSGITVYCVC--DHRRKDVAVVQRKEKELTHSRRG-SMSSVTKLSGLFGDTQSKDP 717
+GA SG+ V C C HRR+ K+ E R S+ S+ +L G +
Sbjct: 616 LGASVSGLLVSCACRRAHRRRG------KDIETPGLPRPLSLRSLARLHGGGPEPPPPSK 669
Query: 718 KPEAILTPLMHNGKLATPGNTAKMLIKADQHHLDLTALPTPESTPTLQQKRKPSRGSREW 777
+A+ TP ++ L P +L LPTPESTP L K + G W
Sbjct: 670 DGDAVQTPQLYTTFLPPPEGVPPP---------ELACLPTPESTPELPVKHLRAAGD-PW 719
Query: 778 ERNQNLINA 786
E NQN NA
Sbjct: 720 EWNQNRNNA 728
>gi|5174673 semaphorin 3A precursor [Homo sapiens]
Length = 771
Score = 313 bits (802), Expect = 5e-85
Identities = 189/518 (36%), Positives = 269/518 (51%), Gaps = 48/518 (9%)
Query: 68 LYIAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKGKH-KDECHNFIKVLLK 126
LY+ A+DHI++ D+ I +K+ W D C+ GK EC NFIKVL
Sbjct: 69 LYVGAKDHIFSFDL-----VNIKDFQKIVWPVSYTRRDECKWAGKDILKECANFIKVLKA 123
Query: 127 KNDDALFVCGTNAFNPSCR-----NYKMDTLEPFGDEF--SGMARCPYDAKHANVALFAD 179
N L+ CGT AF+P C ++ D + + +G + PYD K +L D
Sbjct: 124 YNQTHLYACGTGAFHPICTYIEIGHHPEDNIFKLENSHFENGRGKSPYDPKLLTASLLID 183
Query: 180 GKLYSATVTDFLAIDAVIYRSLGESPTLRTVKHDSKWLKEPYFVQA-------VDYGDYI 232
G+LYS T DF+ D I+R+LG +RT +HDS+WL +P F+ A D +
Sbjct: 184 GELYSGTAADFMGRDFAIFRTLGHHHPIRTEQHDSRWLNDPKFISAHLISESDNPEDDKV 243
Query: 233 YFFFREIAVEYNTMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPG----D 288
YFFFRE A++ GK R+ Q+CKND GG R L +WT+FLKARL CSVPG D
Sbjct: 244 YFFFRENAIDGEHSGKATHARIGQICKNDFGG-HRSLVNKWTTFLKARLICSVPGPNGID 302
Query: 289 SHFYFNILQAVTDVIRINGRD----VVLATFSTPYNSIPGSAVCAYDMLDIASVFTGRFK 344
+HF + DV +N +D VV F+T N GSAVC Y M D+ VF G +
Sbjct: 303 THF-----DELQDVFLMNFKDPKNPVVYGVFTTSSNIFKGSAVCMYSMSDVRRVFLGPYA 357
Query: 345 EQKSPDSTWTPVPDERVPKPRPGCCAGSSSLERYATSNEFPDDTLNFIKTHPLMDEAVPS 404
+ P+ W P RVP PRPG C S + + ++ + PDD + F ++HP M V
Sbjct: 358 HRDGPNYQWVPY-QGRVPYPRPGTCP-SKTFGGFDSTKDLPDDVITFARSHPAMYNPVFP 415
Query: 405 IFNRPWFLRTMVRYRLTKIAVDTAAGPYQNHTVVFLGSEKGIILKFLARIGNSGFLNDSL 464
+ NRP ++T V Y+ T+I VD + V+F+G++ G +LK ++ + + + +
Sbjct: 416 MNNRPIVIKTDVNYQFTQIVVDRVDAEDGQYDVMFIGTDVGTVLKVVSIPKETWYDLEEV 475
Query: 465 FLEEMSVYNSEKCSYDGVEDKRIMGMQLDRASSSLYVAFSTCVIKVPLGRCERHGKCKKT 524
LEEM+V+ E I M+L LY+ + V ++PL RC+ +GK
Sbjct: 476 LLEEMTVFR---------EPTAISAMELSTKQQQLYIGSTAGVAQLPLHRCDIYGKACAE 526
Query: 525 CIASRDPYCGWIKEGGACSHLSPNS-RLTFEQDIERGN 561
C +RDPYC W +G ACS P + R T QDI G+
Sbjct: 527 CCLARDPYCAW--DGSACSRYFPTAKRRTRRQDIRNGD 562
>gi|147904700 semaphorin 5A [Homo sapiens]
Length = 1074
Score = 310 bits (793), Expect = 6e-84
Identities = 195/530 (36%), Positives = 285/530 (53%), Gaps = 44/530 (8%)
Query: 68 LYIAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKGKHKDECHNFIKVLLKK 127
L + AR++++ + + E++ + + W+ +A C KGK K+EC N+I+VLL
Sbjct: 70 LVVGARNYLFRLQL-----EDLSLIQAVEWECDEATKKACYSKGKSKEECQNYIRVLLV- 123
Query: 128 NDDALFVCGTNAFNPSCRNYKMDTLEPFGDEFSGMARCPYDAKHANVALF-ADGKLYSAT 186
D LF CGTNAF P C N + L D+ SGMARCPY +H + AL A G+LY+AT
Sbjct: 124 GGDRLFTCGTNAFTPVCTNRSLSNLTEIHDQISGMARCPYSPQHNSTALLTAGGELYAAT 183
Query: 187 VTDFLAIDAVIYRSLGESPTLRTVKHDSKWLKEPYFVQAVDYGDYIYFFFREIAVEYNTM 246
DF D IYRSLG P LRT +++SKWL EP FV + D G++ YFFFRE AVE++
Sbjct: 184 AMDFPGRDPAIYRSLGILPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVEHD-C 242
Query: 247 GKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNILQAVTDVIRIN 306
GK VF R A+VCKND+GG + +LE WT+F+KARLNCS PG+ FY+N LQ+ + +
Sbjct: 243 GKTVFSRAARVCKNDIGG-RFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSTFFLPEL- 300
Query: 307 GRDVVLATFSTPYNSIPGSAVCAYDMLDIASVFTGRFKEQKSPDSTWTPVPDERVPKPRP 366
D++ F+T NSI SAVC +++ IA F+G FK Q++ S W P P+ P P
Sbjct: 301 --DLIYGIFTTNVNSIAASAVCVFNLSAIAQAFSGPFKYQENSRSAWLPYPN---PNPHF 355
Query: 367 GCCAGSSSLERYATSNEFPDDTLNFIKTHPLMDEAVPSIFNRPWFLRTMVRYRLTKIAVD 426
C L T D FI LM E V + P F+ R+ + +AVD
Sbjct: 356 QCGTVDQGLYVNLTERNL-QDAQKFI----LMHEVVQPVTTVPSFMEDNSRF--SHVAVD 408
Query: 427 TAAGPYQNHTVVFLGSEKGIILKFLARIGNSGFLNDSLFLEEMSVYNSEKCSYDGVEDKR 486
G +++L ++ G I K + + + S LEE+ ++ + +
Sbjct: 409 VVQGREALVHIIYLATDYGTIKKVRVPLNQT---SSSCLLEEIELFPERR-------REP 458
Query: 487 IMGMQLDRASSSLYVAFSTCVIKVPLGRCERHGKCKKTCIASRDPYCGWIKEGGACSHLS 546
I +Q+ + S L+V V+K+PL RC+ + + + TCI ++DPYCGW C+ L
Sbjct: 459 IRSLQILHSQSVLFVGLREHVVKIPLKRCQFY-RTRSTCIGAQDPYCGWDVVMKKCTSLE 517
Query: 547 PNSRLT-FEQDIERGNTDGLGDCHNSFVALNGHSSSLLPST--TTSDSTA 593
+ +T +EQ I C + ++GH P T T +D +A
Sbjct: 518 ESLSMTQWEQSISA--------CPTRNLTVDGHFGVWSPWTPCTHTDGSA 559
>gi|4759092 semaphorin 3B isoform 1 precursor [Homo sapiens]
Length = 749
Score = 306 bits (785), Expect = 5e-83
Identities = 191/538 (35%), Positives = 277/538 (51%), Gaps = 49/538 (9%)
Query: 66 GTLYIAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKGKH-KDECHNFIKVL 124
G L++ A +H+ ++++D +KKL W + + C GK EC NF+K+L
Sbjct: 65 GRLFVGAENHVASLNLDNISKR----AKKLAWPAPVEWREECNWAGKDIGTECMNFVKLL 120
Query: 125 LKKNDDALFVCGTNAFNPSCRNYKMD--------TLEPFGDEFSGMARCPYDAKHANVAL 176
N L CGT AF+P+C ++ L+P G G + PYD +H ++
Sbjct: 121 HAYNRTHLLACGTGAFHPTCAFVEVGHRAEEPVLRLDP-GRIEDGKGKSPYDPRHRAASV 179
Query: 177 FADGKLYSATVTDFLAIDAVIYRSLGESPTLRTVKHDSKWLKEPYFVQAV-------DYG 229
+LYS D + D I+RSLG+ P+LRT HDS+WL EP FV+
Sbjct: 180 LVGEELYSGVAADLMGRDFTIFRSLGQRPSLRTEPHDSRWLNEPKFVKVFWIPESENPDD 239
Query: 230 DYIYFFFREIAVE-YNTMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVP-- 286
D IYFFFRE AVE +G++ RV Q+C+ND+GG QR L +WT+FLKARL CSVP
Sbjct: 240 DKIYFFFRETAVEAAPALGRLSVSRVGQICRNDVGG-QRSLVNKWTTFLKARLVCSVPGV 298
Query: 287 -GDSHFYFNILQAVTDVIRINGRD----VVLATFSTPYNSIPGSAVCAYDMLDIASVFTG 341
GD+HF + DV ++ RD ++ A FST + GSAVC Y M D+ F G
Sbjct: 299 EGDTHF-----DQLQDVFLLSSRDHRTPLLYAVFSTSSSIFQGSAVCVYSMNDVRRAFLG 353
Query: 342 RFKEQKSPDSTWTPVPDERVPKPRPGCCAGSSSLERYATSNEFPDDTLNFIKTHPLMDEA 401
F ++ P W RVP PRPG C S + ++++ +FPDD + F + HPLM +
Sbjct: 354 PFAHKEGPMHQWVSY-QGRVPYPRPGMCP-SKTFGTFSSTKDFPDDVIQFARNHPLMYNS 411
Query: 402 VPSIFNRPWFLRTMVRYRLTKIAVDTAAGPYQNHTVVFLGSEKGIILKFLARIGNSGFLN 461
V RP FL+ Y T+IA D A ++ V+F+G++ G +LK ++ S
Sbjct: 412 VLPTGGRPLFLQVGANYTFTQIAADRVAAADGHYDVLFIGTDVGTVLKVISVPKGSRPSA 471
Query: 462 DSLFLEEMSVYNSEKCSYDGVEDKRIMGMQLDRASSSLYVAFSTCVIKVPLGRCERHGKC 521
+ L LEE+ V+ + + MQ+ LYVA + V ++ L RC HG+
Sbjct: 472 EGLLLEELHVFE---------DSAAVTSMQISSKRHQLYVASRSAVAQIALHRCAAHGRV 522
Query: 522 KKTCIASRDPYCGWIKEGGACSHLSPNSRLTF-EQDIERGNTDGLGDCHNSFVALNGH 578
C +RDPYC W +G AC+ P+++ F QD+ G+ L +S AL H
Sbjct: 523 CTECCLARDPYCAW--DGVACTRFQPSAKRRFRRQDVRNGDPSTLCSGDSSRPALLEH 578
>gi|54607089 semaphorin 3B isoform 2 precursor [Homo sapiens]
Length = 748
Score = 303 bits (775), Expect = 7e-82
Identities = 191/538 (35%), Positives = 277/538 (51%), Gaps = 50/538 (9%)
Query: 66 GTLYIAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKGKH-KDECHNFIKVL 124
G L++ A +H+ ++++D +KKL W + + C GK EC NF+K+L
Sbjct: 65 GRLFVGAENHVASLNLDNISKR----AKKLAWPAPVEWREECNWAGKDIGTECMNFVKLL 120
Query: 125 LKKNDDALFVCGTNAFNPSCRNYKMD--------TLEPFGDEFSGMARCPYDAKHANVAL 176
N L CGT AF+P+C ++ L+P G G + PYD +H ++
Sbjct: 121 HAYNRTHLLACGTGAFHPTCAFVEVGHRAEEPVLRLDP-GRIEDGKGKSPYDPRHRAASV 179
Query: 177 FADGKLYSATVTDFLAIDAVIYRSLGESPTLRTVKHDSKWLKEPYFVQAV-------DYG 229
+LYS D + D I+RSLG+ P+LRT HDS+WL EP FV+
Sbjct: 180 LVGEELYSGVAADLMGRDFTIFRSLGQRPSLRTEPHDSRWLNEPKFVKVFWIPESENPDD 239
Query: 230 DYIYFFFREIAVE-YNTMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVP-- 286
D IYFFFRE AVE +G++ RV Q+C+ND+GG QR L +WT+FLKARL CSVP
Sbjct: 240 DKIYFFFRETAVEAAPALGRLSVSRVGQICRNDVGG-QRSLVNKWTTFLKARLVCSVPGV 298
Query: 287 -GDSHFYFNILQAVTDVIRINGRD----VVLATFSTPYNSIPGSAVCAYDMLDIASVFTG 341
GD+HF + DV ++ RD ++ A FST + GSAVC Y M D+ F G
Sbjct: 299 EGDTHF-----DQLQDVFLLSSRDHRTPLLYAVFSTS-SIFQGSAVCVYSMNDVRRAFLG 352
Query: 342 RFKEQKSPDSTWTPVPDERVPKPRPGCCAGSSSLERYATSNEFPDDTLNFIKTHPLMDEA 401
F ++ P W RVP PRPG C S + ++++ +FPDD + F + HPLM +
Sbjct: 353 PFAHKEGPMHQWVSY-QGRVPYPRPGMCP-SKTFGTFSSTKDFPDDVIQFARNHPLMYNS 410
Query: 402 VPSIFNRPWFLRTMVRYRLTKIAVDTAAGPYQNHTVVFLGSEKGIILKFLARIGNSGFLN 461
V RP FL+ Y T+IA D A ++ V+F+G++ G +LK ++ S
Sbjct: 411 VLPTGGRPLFLQVGANYTFTQIAADRVAAADGHYDVLFIGTDVGTVLKVISVPKGSRPSA 470
Query: 462 DSLFLEEMSVYNSEKCSYDGVEDKRIMGMQLDRASSSLYVAFSTCVIKVPLGRCERHGKC 521
+ L LEE+ V+ + + MQ+ LYVA + V ++ L RC HG+
Sbjct: 471 EGLLLEELHVFE---------DSAAVTSMQISSKRHQLYVASRSAVAQIALHRCAAHGRV 521
Query: 522 KKTCIASRDPYCGWIKEGGACSHLSPNSRLTF-EQDIERGNTDGLGDCHNSFVALNGH 578
C +RDPYC W +G AC+ P+++ F QD+ G+ L +S AL H
Sbjct: 522 CTECCLARDPYCAW--DGVACTRFQPSAKRRFRRQDVRNGDPSTLCSGDSSRPALLEH 577
>gi|91982767 semaphorin 5B isoform 1 [Homo sapiens]
Length = 1151
Score = 289 bits (740), Expect = 8e-78
Identities = 169/486 (34%), Positives = 274/486 (56%), Gaps = 32/486 (6%)
Query: 68 LYIAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKGKHKDECHNFIKVLLKK 127
L + AR++++ + + + + W S + +C+ KGK ++EC N+++VL+
Sbjct: 138 LIVGARNYLFRLSL-----ANVSLLQATEWASSEDTRRSCQSKGKTEEECQNYVRVLIVA 192
Query: 128 NDDALFVCGTNAFNPSCRNYKMDTLEPFGDEFSGMARCPYDAKHANVALFAD-GKLYSAT 186
+F+CGTNAF+P C + ++ L ++ +G+ARCPYD +H + A+ + G+LY+AT
Sbjct: 193 GRK-VFMCGTNAFSPMCTSRQVGNLSRTIEKINGVARCPYDPRHNSTAVISSQGELYAAT 251
Query: 187 VTDFLAIDAVIYRSLGESPTLRTVKHDSKWLKEPYFVQAVDYGDYIYFFFREIAVEYNTM 246
V DF D IYRSLG P LRT +++SKWL EP FV A D G + YFF RE AVE++
Sbjct: 252 VIDFSGRDPAIYRSLGSGPPLRTAQYNSKWLNEPNFVAAYDIGLFAYFFLRENAVEHD-C 310
Query: 247 GKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNILQAVTDVIRIN 306
G+ V+ RVA+VCKND+GG + +LE WT+F+KARLNCS PG+ FY+N LQ+ +
Sbjct: 311 GRTVYSRVARVCKNDVGG-RFLLEDTWTTFMKARLNCSRPGEVPFYYNELQS---AFHLP 366
Query: 307 GRDVVLATFSTPYNSIPGSAVCAYDMLDIASVFTGRFKEQKSPDSTWTPVPDERVPKPRP 366
+D++ F+T NSI SAVCA+++ I+ F G F+ Q++P + W P+ + P P
Sbjct: 367 EQDLIYGVFTTNVNSIAASAVCAFNLSAISQAFNGPFRYQENPRAAWLPIAN---PIPNF 423
Query: 367 GCCAGSSSLERYATSNEFPDDTLNFIKTHPLMDEAVPSIFNRPWFLRTMVRYRLTKIAVD 426
C +L + + +L + LM EAV + P + VR+ + + VD
Sbjct: 424 QC----GTLPETGPNENLTERSLQDAQRLFLMSEAVQPVTPEPCVTQDSVRF--SHLVVD 477
Query: 427 TAAGPYQNHTVVFLGSEKGIILKFLARIGNSGFLNDSLFLEEMSVYNSEKCSYDGVEDKR 486
+ V+++G+E G ILK L+ S +LEE+ V + +
Sbjct: 478 LVQAKDTLYHVLYIGTESGTILKALSTASRS---LHGCYLEELHVLPPGR-------REP 527
Query: 487 IMGMQLDRASSSLYVAFSTCVIKVPLGRCERHGKCKKTCIASRDPYCGWIKEGGACSHLS 546
+ +++ ++ +L+V V++VPL RC + + + C+ +RDPYCGW + CS L
Sbjct: 528 LRSLRILHSARALFVGLRDGVLRVPLERCAAY-RSQGACLGARDPYCGWDGKQQRCSTLE 586
Query: 547 PNSRLT 552
+S ++
Sbjct: 587 DSSNMS 592
>gi|41406086 semaphorin 3D [Homo sapiens]
Length = 777
Score = 289 bits (739), Expect = 1e-77
Identities = 186/533 (34%), Positives = 275/533 (51%), Gaps = 48/533 (9%)
Query: 56 LDIQMIMI--MNGTLYIAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKGKH 113
LD Q +++ G L + A+DHI+ + + + KK+ W + + V+ C++ GK
Sbjct: 68 LDFQTLLLDEERGRLLLGAKDHIFLLSLVDLNKN----FKKIYWPAAKERVELCKLAGKD 123
Query: 114 KD-ECHNFIKVLLKKNDDALFVCGTNAFNPSCRN-----YKMDTLEPFGDEF--SGMARC 165
+ EC NFI+VL N ++VCGT AF+P C YK D + SG +C
Sbjct: 124 ANTECANFIRVLQPYNKTHIYVCGTGAFHPICGYIDLGVYKEDIIFKLDTHNLESGRLKC 183
Query: 166 PYDAKHANVALFADGKLYSATVTDFLAIDAVIYRSLGESPT---LRTVKHDSKWLKEPYF 222
P+D + ++ D LYS T +DFL D RSLG + +RT + WL F
Sbjct: 184 PFDPQQPFASVMTDEYLYSGTASDFLGKDTAFTRSLGPTHDHHYIRTDISEHYWLNGAKF 243
Query: 223 VQAVDY-------GDYIYFFFREIAVEYNTMGKVVFPRVAQVCKNDMGGSQRVLEKQWTS 275
+ D IYFFFRE + E +T K + RV +VCKND+GG QR L +WT+
Sbjct: 244 IGTFFIPDTYNPDDDKIYFFFRESSQEGSTSDKTILSRVGRVCKNDVGG-QRSLINKWTT 302
Query: 276 FLKARLNCSVPGD--SHFYFNILQAVTDVIRINGRD----VVLATFSTPYNSIPGSAVCA 329
FLKARL CS+PG + YF+ LQ D+ + RD VV F+T + GSAVC
Sbjct: 303 FLKARLICSIPGSDGADTYFDELQ---DIYLLPTRDERNPVVYGVFTTTSSIFKGSAVCV 359
Query: 330 YDMLDIASVFTGRFKEQKSPDSTWTPVPDERVPKPRPGCCAGSSSLERYATSNEFPDDTL 389
Y M DI +VF G + ++S D W D R+P PRPG C + ++ +FPDD +
Sbjct: 360 YSMADIRAVFNGPYAHKESADHRWVQY-DGRIPYPRPGTCPSKTYDPLIKSTRDFPDDVI 418
Query: 390 NFIKTHPLMDEAVPSIFNRPWFLRTMVRYRLTKIAVDTAAGPYQNHTVVFLGSEKGIILK 449
+FIK H +M ++V + P F R V YRLT+I VD + V+FLG++ G +LK
Sbjct: 419 SFIKRHSVMYKSVYPVAGGPTFKRINVDYRLTQIVVDHVIAEDGQYDVMFLGTDIGTVLK 478
Query: 450 FLARIGNSGFLNDSLFLEEMSVYNSEKCSYDGVEDKRIMGMQLDRASSSLYVAFSTCVIK 509
++ I + + + LEE+ ++ I+ M+L LY+ +++
Sbjct: 479 VVS-ISKEKWNMEEVVLEELQIFKHSSI---------ILNMELSLKQQQLYIGSRDGLVQ 528
Query: 510 VPLGRCERHGKCKKTCIASRDPYCGWIKEGGACSHLSPNS-RLTFEQDIERGN 561
+ L RC+ +GK C +RDPYC W +G ACS +P S R QD++ G+
Sbjct: 529 LSLHRCDTYGKACADCCLARDPYCAW--DGNACSRYAPTSKRRARRQDVKYGD 579
>gi|6912650 semaphorin 3E [Homo sapiens]
Length = 775
Score = 277 bits (709), Expect = 3e-74
Identities = 167/519 (32%), Positives = 266/519 (51%), Gaps = 46/519 (8%)
Query: 68 LYIAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKGKHKDECHNFIKVLLKK 127
L++ RD +Y++ ++ + Y K++ W S ++ C MKGK EC N+++VL
Sbjct: 70 LFVGGRDLVYSLSLE--RISDGY--KEIHWPSTALKMEECIMKGKDAGECANYVRVLHHY 125
Query: 128 NDDALFVCGTNAFNPSCR----NYKMDT----LEPFGDEFSGMARCPYDAKHANVALFAD 179
N L CGT AF+P C Y ++ LE E G RCP+D + ++
Sbjct: 126 NRTHLLTCGTGAFDPVCAFIRVGYHLEDPLFHLESPRSE-RGRGRCPFDPSSSFISTLIG 184
Query: 180 GKLYSATVTDFLAIDAVIYRSLGESPTLRTVKHDSKWLKEPYFVQAVDYGDY-------I 232
+L++ +D+ + DA I+RS+G +RT D + LKEP FV + D +
Sbjct: 185 SELFAGLYSDYWSRDAAIFRSMGRLAHIRTEHDDERLLKEPKFVGSYMIPDNEDRDDNKV 244
Query: 233 YFFFREIAVEYNTMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHF- 291
YFFF E A+E ++ RV ++C ND+GG QR+L +W++FLKARL CSVPG +
Sbjct: 245 YFFFTEKALEAENNAHAIYTRVGRLCVNDVGG-QRILVNKWSTFLKARLVCSVPGMNGID 303
Query: 292 -YFNILQAVTDVIRINGRD----VVLATFSTPYNSIPGSAVCAYDMLDIASVFTGRFKEQ 346
YF+ L+ DV + RD V+ F+T N G A+C Y M I + F G + +
Sbjct: 304 TYFDELE---DVFLLPTRDHKNPVIFGLFNTTSNIFRGHAICVYHMSSIRAAFNGPYAHK 360
Query: 347 KSPDSTWTPVPDERVPKPRPGCCAGSSSLERYATSNEFPDDTLNFIKTHPLMDEAVPSIF 406
+ P+ W+ V + +VP PRPG CA + RY T+ ++PDD + F ++HPLM +A+
Sbjct: 361 EGPEYHWS-VYEGKVPYPRPGSCASKVNGGRYGTTKDYPDDAIRFARSHPLMYQAIKPAH 419
Query: 407 NRPWFLRTMVRYRLTKIAVDTAAGPYQNHTVVFLGSEKGIILKFLARIGNSGFLNDSLFL 466
+P ++T +Y L +IAVD + V+F+G++ GI+LK + + + L
Sbjct: 420 KKPILVKTDGKYNLKQIAVDRVEAEDGQYDVLFIGTDNGIVLKVITIYNQEMESMEEVIL 479
Query: 467 EEMSVYNSEKCSYDGVEDKRIMGMQLDRASSSLYVAFSTCVIKVPLGRCERHGKCKKTCI 526
EE+ ++ + I+ M++ LY+ ++ V +V C+ +G C
Sbjct: 480 EELQIFK---------DPVPIISMEISSKRQQLYIGSASAVAQVRFHHCDMYGSACADCC 530
Query: 527 ASRDPYCGWIKEGGACSHLSPN----SRLTFEQDIERGN 561
+RDPYC W +G +CS P R QD+ GN
Sbjct: 531 LARDPYCAW--DGISCSRYYPTGTHAKRRFRRQDVRHGN 567
>gi|5454048 semaphorin 3C [Homo sapiens]
Length = 751
Score = 272 bits (695), Expect = 1e-72
Identities = 174/528 (32%), Positives = 269/528 (50%), Gaps = 38/528 (7%)
Query: 54 HRLDIQMIMIMNGT--LYIAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKG 111
H LD +++++ +Y+ ++DHI +++I+ E + + W + V+ C+M G
Sbjct: 50 HPLDYRILLMDEDQDRIYVGSKDHILSLNINNISQEAL----SVFWPASTIKVEECKMAG 105
Query: 112 KHKDE-CHNFIKVLLKKNDDALFVCGTNAFNPSC------RNYKMDTLEPFGDEFSGMAR 164
K C NF++V+ N L+VCG+ AF+P C R + SG R
Sbjct: 106 KDPTHGCGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGKGR 165
Query: 165 CPYDAKHANVALFADGKLYSATVTDFLAIDAVIYRSLGESPTLRTVKHDSKWLKEPYFVQ 224
C ++ V++ + +L+S DF+ DA I+RSL + +RT +H+SKWL EP FV
Sbjct: 166 CSFNPNVNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVD 225
Query: 225 A------VDYGDY-IYFFFREIAVEYNTMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFL 277
A D D +YFFF+E + N K + +A++C ND GG + ++ K WT+FL
Sbjct: 226 AHVIPDGTDPNDAKVYFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSLVNK-WTTFL 284
Query: 278 KARLNCSVPGDS--HFYFNILQAVTDVIRINGRD-VVLATFSTPYNSIPGSAVCAYDMLD 334
KARL CSV + +F+ L+ V + N R +V F+T + GSAVC Y + D
Sbjct: 285 KARLVCSVTDEDGPETHFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHLSD 344
Query: 335 IASVFTGRFKEQKSPDSTWTPVPDERVPKPRPGCCAGSSSLERYATSNEFPDDTLNFIKT 394
I +VF G F ++ P+ R+P PRPG C G + T+ EFPDD + FI+
Sbjct: 345 IQTVFNGPFAHKEGPNHQLISYQG-RIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFIRN 403
Query: 395 HPLMDEAVPSIFNRPWFLRTMVRYRLTKIAVDTAAGPYQNHTVVFLGSEKGIILKFLARI 454
HPLM ++ I RP +R Y+ TKIAVD + V+FLG+++G + K +
Sbjct: 404 HPLMYNSIYPIHKRPLIVRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVVLP 463
Query: 455 GNSGFLNDSLFLEEMSVYNSEKCSYDGVEDKRIMGMQLDRASSSLYVAFSTCVIKVPLGR 514
N+ ++ L LEE+ V+ + I M++ LYV+ + V +V L R
Sbjct: 464 TNNS-VSGELILEELEVFKNH---------APITTMKISSKKQQLYVSSNEGVSQVSLHR 513
Query: 515 CERHGKCKKTCIASRDPYCGWIKEGGACSHLSP-NSRLTFEQDIERGN 561
C +G C +RDPYC W +G +CS P R + QD+ GN
Sbjct: 514 CHIYGTACADCCLARDPYCAW--DGHSCSRFYPTGKRRSRRQDVRHGN 559
>gi|188497703 semaphorin 3F [Homo sapiens]
Length = 785
Score = 269 bits (687), Expect = 1e-71
Identities = 173/548 (31%), Positives = 273/548 (49%), Gaps = 77/548 (14%)
Query: 68 LYIAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKGKHKD-ECHNFIKVLLK 126
+Y+ ++D++ ++D+ + E + + W + ++ C + GK + EC NF++++
Sbjct: 69 MYVGSKDYVLSLDLHDINREPLI----IHWAASPQRIEECVLSGKDVNGECGNFVRLIQP 124
Query: 127 KNDDALFVCGTNAFNPSC---------------------------------------RNY 147
N L+VCGT A+NP C R
Sbjct: 125 WNRTHLYVCGTGAYNPMCTYVNRGRRAQATPWTQTQAVRGRGSRATDGALRPMPTAPRQD 184
Query: 148 KMDTLEPFGDEFSGMARCPYDAKHANVALFADGKLYSATVTDFLAIDAVIYRSLGESPTL 207
+ LEP E SG +CPYD K + + +LY+ DF+ DA I+R+LG+ +
Sbjct: 185 YIFYLEPERLE-SGKGKCPYDPKLDTASALINEELYAGVYIDFMGTDAAIFRTLGKQTAM 243
Query: 208 RTVKHDSKWLKEPYFVQAV-------DYGDYIYFFFREIAVEYNTMGKVVFPRVAQVCKN 260
RT +++S+WL +P F+ A D +YFFFRE + E V+ R+ ++C N
Sbjct: 244 RTDQYNSRWLNDPSFIHAELIPDSAERNDDKLYFFFRERSAEA-PQSPAVYARIGRICLN 302
Query: 261 DMGGSQRVLEKQWTSFLKARLNCSVPGDSHF--YFNILQAV----TDVIRINGRDVVLAT 314
D GG ++ K W++FLKARL CSVPG+ +F+ LQ V T +R V+ A
Sbjct: 303 DDGGHCCLVNK-WSTFLKARLVCSVPGEDGIETHFDELQDVFVQQTQDVR---NPVIYAV 358
Query: 315 FSTPYNSIPGSAVCAYDMLDIASVFTGRFKEQKSPDSTWTPVPDERVPKPRPGCCAGSSS 374
F++ + GSAVC Y M DI VF G F ++ P+ W P ++P PRPG C G +
Sbjct: 359 FTSSGSVFRGSAVCVYSMADIRMVFNGPFAHKEGPNYQWMPFSG-KMPYPRPGTCPGGTF 417
Query: 375 LERYATSNEFPDDTLNFIKTHPLMDEAVPSIFNRPWFLRTMVRYRLTKIAVDTAAGPYQN 434
++ ++PD+ +NF+++HPLM +AV + RP +RT YRLT IAVD
Sbjct: 418 TPSMKSTKDYPDEVINFMRSHPLMYQAVYPLQRRPLVVRTGAPYRLTTIAVDQVDAADGR 477
Query: 435 HTVVFLGSEKGIILKFLARIGNSGFLNDSLFLEEMSVYNSEKCSYDGVEDKRIMGMQLDR 494
+ V+FLG+++G + K + + L + L LEE+ V+ + + M +
Sbjct: 478 YEVLFLGTDRGTVQKVIVLPKDDQEL-EELMLEEVEVFK---------DPAPVKTMTISS 527
Query: 495 ASSSLYVAFSTCVIKVPLGRCERHGKCKKTCIASRDPYCGWIKEGGACSHLSPNS-RLTF 553
LYVA + V + L RC+ +G C +RDPYC W +G ACS + +S R +
Sbjct: 528 KRQQLYVASAVGVTHLSLHRCQAYGAACADCCLARDPYCAW--DGQACSRYTASSKRRSR 585
Query: 554 EQDIERGN 561
QD+ GN
Sbjct: 586 RQDVRHGN 593
>gi|214010220 semaphorin 4D isoform 2 [Homo sapiens]
Length = 738
Score = 268 bits (684), Expect = 3e-71
Identities = 178/496 (35%), Positives = 267/496 (53%), Gaps = 47/496 (9%)
Query: 67 TLYIAARDHIYTVD-IDTSHTE-EIYCSKKLTWKSRQADVDTCRMKGKHKD-ECHNFIKV 123
TLYI AR+ ++ V+ ++ S + E+Y WK + C KGK K EC N+I+V
Sbjct: 61 TLYIGAREAVFAVNALNISEKQHEVY------WKVSEDKKAKCAEKGKSKQTECLNYIRV 114
Query: 124 LLKKNDDALFVCGTNAFNPSCRNYKMDTLEPFGDEFSGMARCPYDAKHANVALFADGKLY 183
L + +L+VCGTNAF P+C + + + + G G RCP+D H+ ++ DG+LY
Sbjct: 115 LQPLSATSLYVCGTNAFQPACDHLNLTSFKFLGKNEDGKGRCPFDPAHSYTSVMVDGELY 174
Query: 184 SATVTDFLAIDAVIYRSLGESPTLRTVKHDSKWLKEPYFVQA----------VDYGDYIY 233
S T +FL + +I R+ SP LRT ++ WL EP FV A D +Y
Sbjct: 175 SGTSYNFLGSEPIISRNSSHSP-LRT-EYAIPWLNEPSFVFADVIRKSPDSPDGEDDRVY 232
Query: 234 FFFREIAVEYNTMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYF 293
FFF E++VEY + +V+ PR+A+VCK D GG R L+K+WTSFLKARL CS P DS F
Sbjct: 233 FFFTEVSVEYEFVFRVLIPRIARVCKGDQGG-LRTLQKKWTSFLKARLICSRP-DSGLVF 290
Query: 294 NILQAVTDVIRINGRDVVL--ATFSTPYNSIPGSAVCAYDMLDIASVFT-GRFKEQKSPD 350
N+L+ V V+R G V + A F+ N++ SAVCAY++ VF+ G++ + + +
Sbjct: 291 NVLRDVF-VLRSPGLKVPVFYALFTPQLNNVGLSAVCAYNLSTAEEVFSHGKYMQSTTVE 349
Query: 351 STWTPVP--DERVPKPRPGCCAGSSS-LERYATSNEFPDDTLNFIKTHPLMDEAVPSIFN 407
+ T + VPKPRPG C S + Y +S PD TL F+K HPLMD++V I N
Sbjct: 350 QSHTKWVRYNGPVPKPRPGACIDSEARAANYTSSLNLPDKTLQFVKDHPLMDDSVTPIDN 409
Query: 408 RPWFLRTMVRYRLTKIAVD-TAAGPYQNHTVVFLGSEKGIILKFLARIGNSGFLNDSLFL 466
RP ++ V Y T+I VD T A + V+F+ +++G L+ ++ L
Sbjct: 410 RPRLIKKDVNY--TQIVVDRTQALDGTVYDVMFVSTDRGA-------------LHKAISL 454
Query: 467 EEMSVYNSEKCSYDGVEDKRIMGMQLDRASSSLYVAFSTCVIKVPLGRCERHGKCKKTCI 526
E E + E + + + + + +Y ++ V++ PL C +HG C + C+
Sbjct: 455 EHAVHIIEETQLFQDFEPVQTLLLSSKKGNRFVYAGSNSGVVQAPLAFCGKHGTC-EDCV 513
Query: 527 ASRDPYCGWIKEGGAC 542
+RDPYC W C
Sbjct: 514 LARDPYCAWSPPTATC 529
>gi|214010218 semaphorin 4D isoform 1 [Homo sapiens]
Length = 862
Score = 268 bits (684), Expect = 3e-71
Identities = 178/496 (35%), Positives = 267/496 (53%), Gaps = 47/496 (9%)
Query: 67 TLYIAARDHIYTVD-IDTSHTE-EIYCSKKLTWKSRQADVDTCRMKGKHKD-ECHNFIKV 123
TLYI AR+ ++ V+ ++ S + E+Y WK + C KGK K EC N+I+V
Sbjct: 61 TLYIGAREAVFAVNALNISEKQHEVY------WKVSEDKKAKCAEKGKSKQTECLNYIRV 114
Query: 124 LLKKNDDALFVCGTNAFNPSCRNYKMDTLEPFGDEFSGMARCPYDAKHANVALFADGKLY 183
L + +L+VCGTNAF P+C + + + + G G RCP+D H+ ++ DG+LY
Sbjct: 115 LQPLSATSLYVCGTNAFQPACDHLNLTSFKFLGKNEDGKGRCPFDPAHSYTSVMVDGELY 174
Query: 184 SATVTDFLAIDAVIYRSLGESPTLRTVKHDSKWLKEPYFVQA----------VDYGDYIY 233
S T +FL + +I R+ SP LRT ++ WL EP FV A D +Y
Sbjct: 175 SGTSYNFLGSEPIISRNSSHSP-LRT-EYAIPWLNEPSFVFADVIRKSPDSPDGEDDRVY 232
Query: 234 FFFREIAVEYNTMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYF 293
FFF E++VEY + +V+ PR+A+VCK D GG R L+K+WTSFLKARL CS P DS F
Sbjct: 233 FFFTEVSVEYEFVFRVLIPRIARVCKGDQGG-LRTLQKKWTSFLKARLICSRP-DSGLVF 290
Query: 294 NILQAVTDVIRINGRDVVL--ATFSTPYNSIPGSAVCAYDMLDIASVFT-GRFKEQKSPD 350
N+L+ V V+R G V + A F+ N++ SAVCAY++ VF+ G++ + + +
Sbjct: 291 NVLRDVF-VLRSPGLKVPVFYALFTPQLNNVGLSAVCAYNLSTAEEVFSHGKYMQSTTVE 349
Query: 351 STWTPVP--DERVPKPRPGCCAGSSS-LERYATSNEFPDDTLNFIKTHPLMDEAVPSIFN 407
+ T + VPKPRPG C S + Y +S PD TL F+K HPLMD++V I N
Sbjct: 350 QSHTKWVRYNGPVPKPRPGACIDSEARAANYTSSLNLPDKTLQFVKDHPLMDDSVTPIDN 409
Query: 408 RPWFLRTMVRYRLTKIAVD-TAAGPYQNHTVVFLGSEKGIILKFLARIGNSGFLNDSLFL 466
RP ++ V Y T+I VD T A + V+F+ +++G L+ ++ L
Sbjct: 410 RPRLIKKDVNY--TQIVVDRTQALDGTVYDVMFVSTDRGA-------------LHKAISL 454
Query: 467 EEMSVYNSEKCSYDGVEDKRIMGMQLDRASSSLYVAFSTCVIKVPLGRCERHGKCKKTCI 526
E E + E + + + + + +Y ++ V++ PL C +HG C + C+
Sbjct: 455 EHAVHIIEETQLFQDFEPVQTLLLSSKKGNRFVYAGSNSGVVQAPLAFCGKHGTC-EDCV 513
Query: 527 ASRDPYCGWIKEGGAC 542
+RDPYC W C
Sbjct: 514 LARDPYCAWSPPTATC 529
>gi|157388902 semaphorin 4C [Homo sapiens]
Length = 833
Score = 254 bits (649), Expect = 3e-67
Identities = 166/521 (31%), Positives = 261/521 (50%), Gaps = 43/521 (8%)
Query: 66 GTLYIAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKGKHKD-ECHNFIKVL 124
G LY+ AR+ ++ + E + ++W++ C KGK+ EC NFI+ L
Sbjct: 63 GLLYVGAREALFAFSM-----EALELQGAISWEAPVEKKTECIQKGKNNQTECFNFIRFL 117
Query: 125 LKKNDDALFVCGTNAFNPSCRNYKMDTLEPFGDEFS-GMARCPYDAKHANVALFADGKLY 183
N L+VCGT AF P C M T EF G +CPYD + L DG+LY
Sbjct: 118 QPYNASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELY 177
Query: 184 SATVTDFLAIDAVIYRSLGESPTLRTVKHDSKWLKEPYFVQA----------VDYGDYIY 233
SAT+ +FL + +I R++G +++T ++ + WL EP+FV + D +Y
Sbjct: 178 SATLNNFLGTEPIILRNMGPHHSMKT-EYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVY 236
Query: 234 FFFREIAVEYNTMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYF 293
FFFRE AVE + + V RVA+VCK DMGG+ R L+++WT+FLKARL CS P + YF
Sbjct: 237 FFFRERAVESDCYAEQVVARVARVCKGDMGGA-RTLQRKWTTFLKARLACSAP-NWQLYF 294
Query: 294 NILQAVTDVIRINGRDVV-LATFSTPYNSIPGSAVCAYDMLDIASVFTGRFKEQKSPDST 352
N LQA+ + + + F + + SA+C Y + +I VF G +KE
Sbjct: 295 NQLQAMHTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQK 354
Query: 353 WTPVPDERVPKPRPGCCAGS-SSLERYATSNEFPDDTLNFIKTHPLMDEAVPSIFNRPWF 411
W D VP PRPG C + Y +S E PD+ LNF+K HPLM+E V ++RP
Sbjct: 355 WDRYTDP-VPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLL 413
Query: 412 LRTMVRYRLTKIAVDTAAG-PYQNHTVVFLGSEKGIILKFLARIGNSGFLNDSLFLEEMS 470
++ + T + D G +TV+F+G+ G +LK ++ +G L +EE+
Sbjct: 414 VKKGTNF--THLVADRVTGLDGATYTVLFIGTGDGWLLKAVS-LGPWVHL-----IEELQ 465
Query: 471 VYNSEKCSYDGVEDKRIMGMQLDRASSSLYVAFSTCVIKVPLGRCERHGKCKKTCIASRD 530
+++ E + + L ++ L+ + ++++P+ C ++ C C+ +RD
Sbjct: 466 LFDQEP----------MRSLVLSQSKKLLFAGSRSQLVQLPVADCMKYRSC-ADCVLARD 514
Query: 531 PYCGWIKEGGACSHLSPNSRLTFEQDIERGNTDGLGDCHNS 571
PYC W C + +S Q + +T G+ + S
Sbjct: 515 PYCAWSVNTSRCVAVGGHSGSLLIQHVMTSDTSGICNLRGS 555
>gi|9910362 semaphorin sem2 [Homo sapiens]
Length = 782
Score = 251 bits (641), Expect = 2e-66
Identities = 172/518 (33%), Positives = 250/518 (48%), Gaps = 43/518 (8%)
Query: 68 LYIAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKGKHK-DECHNFIKVLLK 126
L++ D +Y++ +D + + +++ W + + C KG+ EC NF++VL
Sbjct: 70 LFLGGLDALYSLRLDQAWPDP----REVLWPPQPGQREECVRKGRDPLTECANFVRVLQP 125
Query: 127 KNDDALFVCGTNAFNPSC-------RNYKMDTLEPFGDEFSGMARCPYDAKHANVALFAD 179
N L CGT AF P+C R + LEP G SG RCP++ + F D
Sbjct: 126 HNRTHLLACGTGAFQPTCALITVGHRGEHVLHLEP-GSVESGRGRCPHEPSRPFASTFID 184
Query: 180 GKLYSATVTDFLAIDAVIYRSLGESPTLRTVKHDSKWLKEPYFVQAVDY-------GDYI 232
G+LY+ DFL +A+I+RS G P LR+ D L +P FV A D +
Sbjct: 185 GELYTGLTADFLGREAMIFRSGGPRPALRS-DSDQSLLHDPRFVMAARIPENSDQDNDKV 243
Query: 233 YFFFRE-IAVEYNTMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGD--S 289
YFFF E + V RV +VC ND GG QRVL +W++FLKARL CSVPG +
Sbjct: 244 YFFFSETVPSPDGGSNHVTVSRVGRVCVNDAGG-QRVLVNKWSTFLKARLVCSVPGPGGA 302
Query: 290 HFYFNILQAVTDVIRINGRDV-VLATFSTPYNSIPGSAVCAYDMLDIASVFTGRFKEQKS 348
+F+ L+ V + G+ + V A FST G AVC Y M DI VF G F +
Sbjct: 303 ETHFDQLEDVFLLWPKAGKSLEVYALFSTVSAVFQGFAVCVYHMADIWEVFNGPFAHRDG 362
Query: 349 PDSTWTPVPDERVPKPRPGCCAGSSSLER---YATSNEFPDDTLNFIKTHPLMDEAVPSI 405
P W P +VP PRPG C + + + ++ ++PD+ L F + HPLM V
Sbjct: 363 PQHQWGPYGG-KVPFPRPGVCPSKMTAQPGRPFGSTKDYPDEVLQFARAHPLMFWPVRPR 421
Query: 406 FNRPWFLRTMVRYRLTKIAVDTAAGPYQNHTVVFLGSEKGIILKFLARIGNSGFLNDSLF 465
RP ++T + +L +I VD + V+FLG++ G +LK +A + +
Sbjct: 422 HGRPVLVKTHLAQQLHQIVVDRVEAEDGTYDVIFLGTDSGSVLKVIALQAGGSAEPEEVV 481
Query: 466 LEEMSVYNSEKCSYDGVEDKRIMGMQLDRASSSLYVAFSTCVIKVPLGRCERHGKCKKTC 525
LEE+ V+ I M++ LYV V ++ L +CE +G C
Sbjct: 482 LEELQVFK---------VPTPITEMEISVKRQMLYVGSRLGVAQLRLHQCETYGTACAEC 532
Query: 526 IASRDPYCGWIKEGGACSHLSPN--SRLTFEQDIERGN 561
+RDPYC W +G +C+H P+ R QDI GN
Sbjct: 533 CLARDPYCAW--DGASCTHYRPSLGKRRFRRQDIRHGN 568
>gi|21361914 semaphorin B [Homo sapiens]
Length = 761
Score = 244 bits (623), Expect = 3e-64
Identities = 166/508 (32%), Positives = 262/508 (51%), Gaps = 49/508 (9%)
Query: 67 TLYIAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKGKHKD-ECHNFIKVLL 125
TLY+ AR+ I +DI + + W + C K K + +C NFI+VL+
Sbjct: 75 TLYVGAREAILALDIQDPGVPRL--KNMIPWPASDRKKSECAFKKKSNETQCFNFIRVLV 132
Query: 126 KKNDDALFVCGTNAFNPSCRNYKMDT--LEPFGDE--FSGMARCPYDAKHANVALFADGK 181
N L+ CGT AF+P+C ++ L P ++ G + P+D H + A+ DG
Sbjct: 133 SYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQSPFDPAHKHTAVLVDGM 192
Query: 182 LYSATVTDFLAIDAVIYRSLGESPTLRTVKHDSKWL-KEPYFVQAVDYGDYIYFFFREIA 240
LYS T+ +FL + ++ R+LG P L+T + +WL + FV A+ +YFFF E A
Sbjct: 193 LYSGTMNNFLGSEPILMRTLGSQPVLKT-DNFLRWLHHDASFVAAIPSTQVVYFFFEETA 251
Query: 241 VEYNTMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNILQ-AV 299
E++ ++ RVA+VCKND+GG +++L+K+WT+FLKA+L C+ PG FN+++ AV
Sbjct: 252 SEFDFFERLHTSRVARVCKNDVGG-EKLLQKKWTTFLKAQLLCTQPG--QLPFNVIRHAV 308
Query: 300 TDVIRINGRDVVLATFSTPY--NSIPGSAVCAYDMLDIASVFTGRFKEQKSPDSTWTPVP 357
+ A F++ + SAVCA+ +LDI VF G++KE S WT
Sbjct: 309 LLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKELNKETSRWTTYR 368
Query: 358 DERVPKPRPGCCA-GSSSLERYATSNEFPDDTLNFIKTHPLMDEAVPSIFNRPWFLRTMV 416
PRPG C+ G SS D L F+K H LMDE + P +++ V
Sbjct: 369 GPET-NPRPGSCSVGPSS-----------DKALTFMKDHFLMDE---QVVGTPLLVKSGV 413
Query: 417 RYRLTKIAVDTAAG-PYQNHTVVFLGSEKGIILKFLARIGNSGFLNDSLFLEEMSVYNSE 475
Y T++AV+TA G +H V++LG+ G + K + +S L +EE+ ++
Sbjct: 414 EY--TRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGDSSAHL-----VEEIQLF--- 463
Query: 476 KCSYDGVEDKRIMGMQLDRASSSLYVAFSTCVIKVPLGRCERHGKCKKTCIASRDPYCGW 535
+ + + +QL +++V FS V +VP C + C C+ +RDP+C W
Sbjct: 464 ------PDPEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVYESC-VDCVLARDPHCAW 516
Query: 536 IKEGGACSHLSPNSRLTFEQDIERGNTD 563
E C LS + +++QD+ERGN +
Sbjct: 517 DPESRTCCLLSAPNLNSWKQDMERGNPE 544
>gi|39777610 semaphorin 4B precursor [Homo sapiens]
Length = 837
Score = 243 bits (621), Expect = 5e-64
Identities = 170/506 (33%), Positives = 252/506 (49%), Gaps = 58/506 (11%)
Query: 67 TLYIAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKGKHKD-ECHNFIKVLL 125
TLY+ AR+ ++ + + S ++L W + C KGK +C N+IK+LL
Sbjct: 81 TLYVGAREALFALSSNLSFLPGGEY-QELLWGADAEKKQQCSFKGKDPQRDCQNYIKILL 139
Query: 126 KKNDDALFVCGTNAFNPSCRNYKMDTLEPFGDEFS------GMARCPYDAKHANVALFAD 179
+ LF CGT AF+P C M+ DE G RCP+D + AL D
Sbjct: 140 PLSGSHLFTCGTAAFSPMCTYINMENFTLARDEKGNVLLEDGKGRCPFDPNFKSTALVVD 199
Query: 180 GKLYSATVTDFLAIDAVIYRSLGESPTLRTVKHDSKWLKEPYFVQAV----------DYG 229
G+LY+ TV+ F D I RS PT + WL++P FV +
Sbjct: 200 GELYTGTVSSFQGNDPAISRSQSLRPT--KTESSLNWLQDPAFVASAYIPESLGSLQGDD 257
Query: 230 DYIYFFFREIAVEYNTMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDS 289
D IYFFF E E+ + R+A++CK D GG +RVL+++WTSFLKA+L CS P D
Sbjct: 258 DKIYFFFSETGQEFEFFENTIVSRIARICKGDEGG-ERVLQQRWTSFLKAQLLCSRPDDG 316
Query: 290 HFYFNILQAVTDVIRI-----NGRDVVL-ATFSTPYN--SIPGSAVCAYDMLDIASVFTG 341
F FN+LQ DV + + RD + F++ ++ + GSAVC + M D+ VF+G
Sbjct: 317 -FPFNVLQ---DVFTLSPSPQDWRDTLFYGVFTSQWHRGTTEGSAVCVFTMKDVQRVFSG 372
Query: 342 RFKEQKSPDSTWTPVPDERVPKPRPGCCAGSSSLERYATSN-EFPDDTLNFIKTHPLMDE 400
+KE W V VP PRPG C +S+ ER S+ + PD LNF+K H LMD
Sbjct: 373 LYKEVNRETQQWYTV-THPVPTPRPGACITNSARERKINSSLQLPDRVLNFLKDHFLMDG 431
Query: 401 AVPSIFNRPWFLRTMVRYRLTKIAVDTAAGPYQNHTVVFLGSEKGIILKFLARIGNSGFL 460
V S R L+ RY+ ++AV G + + V+FLG+ G + K ++ +G +
Sbjct: 432 QVRS---RMLLLQPQARYQ--RVAVHRVPGLHHTYDVLFLGTGDGRLHKAVS-VGPRVHI 485
Query: 461 NDSLFLEEMSVYNSEKCSYDGVEDKRIMGMQLDRASSSLYVAFSTCVIKVPLGRCERHGK 520
+EE+ +++S + + + LD LY A + V++VP+ C +
Sbjct: 486 -----IEELQIFSS---------GQPVQNLLLDTHRGLLYAASHSGVVQVPMANCSLYRS 531
Query: 521 CKKTCIASRDPYCGWIKEGGACSHLS 546
C C+ +RDPYC W G +C H+S
Sbjct: 532 C-GDCLLARDPYCAW--SGSSCKHVS 554
>gi|39777608 semaphorin 4B precursor [Homo sapiens]
Length = 837
Score = 243 bits (621), Expect = 5e-64
Identities = 170/506 (33%), Positives = 252/506 (49%), Gaps = 58/506 (11%)
Query: 67 TLYIAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKGKHKD-ECHNFIKVLL 125
TLY+ AR+ ++ + + S ++L W + C KGK +C N+IK+LL
Sbjct: 81 TLYVGAREALFALSSNLSFLPGGEY-QELLWGADAEKKQQCSFKGKDPQRDCQNYIKILL 139
Query: 126 KKNDDALFVCGTNAFNPSCRNYKMDTLEPFGDEFS------GMARCPYDAKHANVALFAD 179
+ LF CGT AF+P C M+ DE G RCP+D + AL D
Sbjct: 140 PLSGSHLFTCGTAAFSPMCTYINMENFTLARDEKGNVLLEDGKGRCPFDPNFKSTALVVD 199
Query: 180 GKLYSATVTDFLAIDAVIYRSLGESPTLRTVKHDSKWLKEPYFVQAV----------DYG 229
G+LY+ TV+ F D I RS PT + WL++P FV +
Sbjct: 200 GELYTGTVSSFQGNDPAISRSQSLRPT--KTESSLNWLQDPAFVASAYIPESLGSLQGDD 257
Query: 230 DYIYFFFREIAVEYNTMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDS 289
D IYFFF E E+ + R+A++CK D GG +RVL+++WTSFLKA+L CS P D
Sbjct: 258 DKIYFFFSETGQEFEFFENTIVSRIARICKGDEGG-ERVLQQRWTSFLKAQLLCSRPDDG 316
Query: 290 HFYFNILQAVTDVIRI-----NGRDVVL-ATFSTPYN--SIPGSAVCAYDMLDIASVFTG 341
F FN+LQ DV + + RD + F++ ++ + GSAVC + M D+ VF+G
Sbjct: 317 -FPFNVLQ---DVFTLSPSPQDWRDTLFYGVFTSQWHRGTTEGSAVCVFTMKDVQRVFSG 372
Query: 342 RFKEQKSPDSTWTPVPDERVPKPRPGCCAGSSSLERYATSN-EFPDDTLNFIKTHPLMDE 400
+KE W V VP PRPG C +S+ ER S+ + PD LNF+K H LMD
Sbjct: 373 LYKEVNRETQQWYTV-THPVPTPRPGACITNSARERKINSSLQLPDRVLNFLKDHFLMDG 431
Query: 401 AVPSIFNRPWFLRTMVRYRLTKIAVDTAAGPYQNHTVVFLGSEKGIILKFLARIGNSGFL 460
V S R L+ RY+ ++AV G + + V+FLG+ G + K ++ +G +
Sbjct: 432 QVRS---RMLLLQPQARYQ--RVAVHRVPGLHHTYDVLFLGTGDGRLHKAVS-VGPRVHI 485
Query: 461 NDSLFLEEMSVYNSEKCSYDGVEDKRIMGMQLDRASSSLYVAFSTCVIKVPLGRCERHGK 520
+EE+ +++S + + + LD LY A + V++VP+ C +
Sbjct: 486 -----IEELQIFSS---------GQPVQNLLLDTHRGLLYAASHSGVVQVPMANCSLYRS 531
Query: 521 CKKTCIASRDPYCGWIKEGGACSHLS 546
C C+ +RDPYC W G +C H+S
Sbjct: 532 C-GDCLLARDPYCAW--SGSSCKHVS 554
>gi|19923279 semaphorin W [Homo sapiens]
Length = 770
Score = 231 bits (588), Expect = 3e-60
Identities = 165/515 (32%), Positives = 248/515 (48%), Gaps = 45/515 (8%)
Query: 67 TLYIAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKGKHKDECHNFIKVLLK 126
TLY+ ARD I+ + + S +++ W +A CR KGK +DECHNF+++L
Sbjct: 76 TLYVGARDTIFALSLPFSGERP----RRIDWMVPEAHRQNCRKKGKKEDECHNFVQILAI 131
Query: 127 KNDDALFVCGTNAFNPSCRNYKMDTLEPFGDEFSGMARCPYDAKHANVALFADGKLYSAT 186
N L CGT AF+P C + + SG +CP++ + A+ A G LY+AT
Sbjct: 132 ANASHLLTCGTFAFDPKCGVIDVSRFQQVERLESGRGKCPFEPAQRSAAVMAGGVLYAAT 191
Query: 187 VTDFLAIDAVIYRSLGESPTLRTVKHDSKWLKEPYFVQAV----------DYGDYIYFFF 236
V ++L + +I R++G + WL P FV AV D D IYFFF
Sbjct: 192 VKNYLGTEPIITRAVGRAEDWIRTDTLPSWLNAPAFVAAVALSPAEWGDEDGDDEIYFFF 251
Query: 237 REIAVEYNTMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNIL 296
E + +++ ++ PRVA+VC D+GG ++ L+++WT+FLKA L C PG H + +
Sbjct: 252 TETSRAFDSYERIKVPRVARVCAGDLGG-RKTLQQRWTTFLKADLLC--PGPEHGRASSV 308
Query: 297 QAVTDVIRIN---GRDVVLATFSTPYNSIPGSAVCAYDMLDIASVFTGRFKEQKSPDSTW 353
V+R G + FS+ + SAVCA+ DI +V G F+E K +
Sbjct: 309 LQDVAVLRPELGAGTPIFYGIFSSQWEGATISAVCAFRPQDIRTVLNGPFRELKHDCNRG 368
Query: 354 TPVPDERVPKPRPG-CCAGSSSLERYATSNEFPDDTLNFIKTHPLMDEAVPSIFNRPWFL 412
PV D VP+PRPG C + L + +S PD L FI+ HPLMD V P +
Sbjct: 369 LPVVDNDVPQPRPGECITNNMKLRHFGSSLSLPDRVLTFIRDHPLMDRPVFPADGHPLLV 428
Query: 413 RTMVRY-RLTKIAVDTAAGPYQNHTVVFLGSEKGIILKFLARIGNSGFLNDSLFLEEMSV 471
T Y R+ V + +G + + V++LG+E G + + RIG LE++++
Sbjct: 429 TTDTAYLRVVAHRVTSLSG--KEYDVLYLGTEDGHLHR-AVRIG-----AQLSVLEDLAL 480
Query: 472 YNSEKCSYDGVEDKRIMGMQLDRASSSLYVAFSTCVIKVPLGRCERHGKCKKTCIASRDP 531
+ E + + M+L S L V T V +V C R C + CI ++DP
Sbjct: 481 F---------PEPQPVENMKL--YHSWLLVGSRTEVTQVNTTNCGRLQSCSE-CILAQDP 528
Query: 532 YCGWIKEGGAC-SHLSPNSRLTFEQDIERGNTDGL 565
C W C +H + L QDIE + L
Sbjct: 529 VCAWSFRLDECVAHAGEHRGLV--QDIESADVSSL 561
>gi|28872814 semaphorin 4G [Homo sapiens]
Length = 843
Score = 228 bits (581), Expect = 2e-59
Identities = 166/497 (33%), Positives = 236/497 (47%), Gaps = 55/497 (11%)
Query: 93 KKLTWKSRQADVDTCRMKGKHKD-ECHNFIKVLLKKNDDALFVCGTNAFNPSCRNYKMDT 151
K++ W++ C KGK+ EC N ++ L + N L+ CGT+AF P C +
Sbjct: 90 KEIHWEASPEMQSKCHQKGKNNQTECFNHVRFLQRLNSTHLYACGTHAFQPLCAAIDAEA 149
Query: 152 LEPFGDEFSGMARCPYDAKHANVALFADGKLYSATVTDFLAIDAVIYRSLGESPTLRTVK 211
G +CPYD L DG LY+AT +F +I + R +LRT +
Sbjct: 150 FTLPTSFEEGKEKCPYDPARGFTGLIIDGGLYTATRYEFRSIPDI--RRSRHPHSLRTEE 207
Query: 212 HDSKWLKEPYFV----------QAVDYGDYIYFFFREIAVEYNT------MGKVVFPRVA 255
WL + FV AV D +Y+FF E A E + RVA
Sbjct: 208 TPMHWLNDAEFVFSVLVRESKASAVGDDDKVYYFFTERATEEGSGSFTQSRSSHRVARVA 267
Query: 256 QVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNILQAVTDV-IRINGRDVVLAT 314
+VCK D+GG +++L+K+WTSFLKARL C +P + L+ V + + R A
Sbjct: 268 RVCKGDLGG-KKILQKKWTSFLKARLICHIP-----LYETLRGVCSLDAETSSRTHFYAA 321
Query: 315 F--STPYNSIPGSAVCAYDMLDIASVFTGRFKEQKSPDSTWTPVPDERVPKPRPG-CCAG 371
F ST + ++ SA+C YD+ +I +VF G + E + W + VP+PRPG C
Sbjct: 322 FTLSTQWKTLEASAICRYDLAEIQAVFAGPYMEYQDGSRRWGRY-EGGVPEPRPGSCITD 380
Query: 372 SSSLERYATSNEFPDDTLNFIKTHPLMDEAVPSIFNRPWFLRTMVRY-RLTKIAVDTAAG 430
S + Y +S + P L+F+K HPLM V RP L+ +RY LT V T AG
Sbjct: 381 SLRSQGYNSSQDLPSLVLDFVKLHPLMARPVVPTRGRPLLLKRNIRYTHLTGTPVTTPAG 440
Query: 431 PYQNHTVVFLGSEKGIILKFLARIGNSGFLNDSLFLEEMSVYNSEKCSYDGVEDKRIMGM 490
P + ++FLG+ G I K A + SG +EE V+ E + + +
Sbjct: 441 P--TYDLLFLGTADGWIHK--AVVLGSGM----HIIEETQVFR---------ESQSVENL 483
Query: 491 QLDRASSSLYVAFSTCVIKVPLGRCERHGKCKKTCIASRDPYCGWIKEGGAC------SH 544
+ SLYV + VI++PL C R+ C CI +RDPYCGW AC ++
Sbjct: 484 VISLLQHSLYVGAPSGVIQLPLSSCSRYRSC-YDCILARDPYCGWDPGTHACAAATTIAN 542
Query: 545 LSPNSRLTFEQDIERGN 561
S SR QDIERGN
Sbjct: 543 RSQGSRTALIQDIERGN 559
>gi|4504237 semaphorin 7A isoform 1 preproprotein [Homo sapiens]
Length = 666
Score = 147 bits (372), Expect = 4e-35
Identities = 141/495 (28%), Positives = 210/495 (42%), Gaps = 61/495 (12%)
Query: 65 NGTLYIAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKGKHKDECHNFIKVL 124
+ ++++ R +Y D + R ++ + + K +C N+I L
Sbjct: 84 SSSVWVGGRGKVYLFDFPEGKNASV----------RTVNIGSTKGSCLDKRDCENYI-TL 132
Query: 125 LKKNDDALFVCGTNAFNPSCRNYKMDTLEPFGDEFSGMARCPYDAKHANVALFADGKLYS 184
L++ + L CGTNA +PSC N T+ P G E G A P+ ++ LF ++YS
Sbjct: 133 LERRSEGLLACGTNARHPSCWNLVNGTVVPLG-EMRGYA--PFSPDENSLVLFEGDEVYS 189
Query: 185 ATVTDFLAIDAVIYRSL-GESP--TLRTVKHDSKWLKEPYFVQAVDYGDYIYFFFREIAV 241
+R + GES T TV + +++K Q Y D IY+FFRE
Sbjct: 190 TIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFIKATIVHQDQAYDDKIYYFFREDNP 249
Query: 242 EYNTMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNILQAVTD 301
+ N + RVAQ+C+ D GG + +W +FLKA L CS ++ FN LQ V
Sbjct: 250 DKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVCS-DAATNKNFNRLQDVFL 308
Query: 302 VIRING--RDV-VLATFSTPYNSIPGSAVCAYDMLDIASVFTGRFKEQKSPDSTWTPVPD 358
+ +G RD V FS P+N SAVC Y + DI VF R K S+
Sbjct: 309 LPDPSGQWRDTRVYGVFSNPWNY---SAVCVYSLGDIDKVF--RTSSLKGYHSS------ 357
Query: 359 ERVPKPRPGCCAGSSSLERYATSNEFPDDTLNFIKTHPLMDEAVPSI--FNRPWFLRTMV 416
+P PRPG C P +T HP + + V + P F
Sbjct: 358 --LPNPRPGKC--------LPDQQPIPTETFQVADRHPEVAQRVEPMGPLKTPLF---HS 404
Query: 417 RYRLTKIAVDTAAGPY-QNHTVVFLGSEKGIILKFLARIGNSGFLNDSLFLEEMSVYNSE 475
+Y K+AV + + V++L +++G I K + G S M +
Sbjct: 405 KYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHK----VVEPGEQEHSFAFNIMEIQPFR 460
Query: 476 KCSYDGVEDKRIMGMQLDRASSSLYVAFSTCVIKVPLGRCERHGKCKKTCIASRDPYCGW 535
+ + I M LD LYV+ V +VPL CE +G C+ SRDPYCGW
Sbjct: 461 RAA-------AIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCGW 513
Query: 536 IKEGGACSHLSPNSR 550
+ G C + + R
Sbjct: 514 --DQGRCISIYSSER 526
>gi|225637520 semaphorin 7A isoform 2 preproprotein [Homo sapiens]
Length = 652
Score = 145 bits (367), Expect = 1e-34
Identities = 136/446 (30%), Positives = 195/446 (43%), Gaps = 51/446 (11%)
Query: 114 KDECHNFIKVLLKKNDDALFVCGTNAFNPSCRNYKMDTLEPFGDEFSGMARCPYDAKHAN 173
+ +C N+I LL++ + L CGTNA +PSC N T+ P G E G A P+ +
Sbjct: 109 RTDCENYI-TLLERRSEGLLACGTNARHPSCWNLVNGTVVPLG-EMRGYA--PFSPDENS 164
Query: 174 VALFADGKLYSATVTDFLAIDAVIYRSL-GESP--TLRTVKHDSKWLKEPYFVQAVDYGD 230
+ LF ++YS +R + GES T TV + +++K Q Y D
Sbjct: 165 LVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFIKATIVHQDQAYDD 224
Query: 231 YIYFFFREIAVEYNTMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSH 290
IY+FFRE + N + RVAQ+C+ D GG + +W +FLKA L CS ++
Sbjct: 225 KIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVCS-DAATN 283
Query: 291 FYFNILQAVTDVIRING--RDV-VLATFSTPYNSIPGSAVCAYDMLDIASVFTGRFKEQK 347
FN LQ V + +G RD V FS P+N SAVC Y + DI VF R K
Sbjct: 284 KNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY---SAVCVYSLGDIDKVF--RTSSLK 338
Query: 348 SPDSTWTPVPDERVPKPRPGCCAGSSSLERYATSNEFPDDTLNFIKTHPLMDEAVPSI-- 405
S+ +P PRPG C P +T HP + + V +
Sbjct: 339 GYHSS--------LPNPRPGKC--------LPDQQPIPTETFQVADRHPEVAQRVEPMGP 382
Query: 406 FNRPWFLRTMVRYRLTKIAVDTAAGPY-QNHTVVFLGSEKGIILKFLARIGNSGFLNDSL 464
P F +Y K+AV + + V++L +++G I K + G S
Sbjct: 383 LKTPLF---HSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHK----VVEPGEQEHSF 435
Query: 465 FLEEMSVYNSEKCSYDGVEDKRIMGMQLDRASSSLYVAFSTCVIKVPLGRCERHGKCKKT 524
M + + + I M LD LYV+ V +VPL CE +G
Sbjct: 436 AFNIMEIQPFRRAA-------AIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHG 488
Query: 525 CIASRDPYCGWIKEGGACSHLSPNSR 550
C+ SRDPYCGW + G C + + R
Sbjct: 489 CLMSRDPYCGW--DQGRCISIYSSER 512
>gi|225637524 semaphorin 7A isoform 3 [Homo sapiens]
Length = 501
Score = 115 bits (287), Expect = 3e-25
Identities = 115/394 (29%), Positives = 166/394 (42%), Gaps = 47/394 (11%)
Query: 166 PYDAKHANVALFADGKLYSATVTDFLAIDAVIYRSL-GESP--TLRTVKHDSKWLKEPYF 222
P+ ++ LF ++YS +R + GES T TV + +++K
Sbjct: 6 PFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFIKATIV 65
Query: 223 VQAVDYGDYIYFFFREIAVEYNTMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLN 282
Q Y D IY+FFRE + N + RVAQ+C+ D GG + +W +FLKA L
Sbjct: 66 HQDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLV 125
Query: 283 CSVPGDSHFYFNILQAVTDVIRING--RDV-VLATFSTPYNSIPGSAVCAYDMLDIASVF 339
CS ++ FN LQ V + +G RD V FS P+N SAVC Y + DI VF
Sbjct: 126 CS-DAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY---SAVCVYSLGDIDKVF 181
Query: 340 TGRFKEQKSPDSTWTPVPDERVPKPRPGCCAGSSSLERYATSNEFPDDTLNFIKTHPLMD 399
R K S+ +P PRPG C P +T HP +
Sbjct: 182 --RTSSLKGYHSS--------LPNPRPGKC--------LPDQQPIPTETFQVADRHPEVA 223
Query: 400 EAVPSI--FNRPWFLRTMVRYRLTKIAVDTAAGPY-QNHTVVFLGSEKGIILKFLARIGN 456
+ V + P F +Y K+AV + + V++L +++G I K +
Sbjct: 224 QRVEPMGPLKTPLF---HSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHK----VVE 276
Query: 457 SGFLNDSLFLEEMSVYNSEKCSYDGVEDKRIMGMQLDRASSSLYVAFSTCVIKVPLGRCE 516
G S M + + + I M LD LYV+ V +VPL CE
Sbjct: 277 PGEQEHSFAFNIMEIQPFRRAA-------AIQTMSLDAERRKLYVSSQWEVSQVPLDLCE 329
Query: 517 RHGKCKKTCIASRDPYCGWIKEGGACSHLSPNSR 550
+G C+ SRDPYCGW + G C + + R
Sbjct: 330 VYGGGCHGCLMSRDPYCGW--DQGRCISIYSSER 361
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,824,739
Number of Sequences: 37866
Number of extensions: 2069296
Number of successful extensions: 6804
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 103
Number of HSP's that attempted gapping in prelim test: 6402
Number of HSP's gapped (non-prelim): 296
length of query: 1030
length of database: 18,247,518
effective HSP length: 112
effective length of query: 918
effective length of database: 14,006,526
effective search space: 12857990868
effective search space used: 12857990868
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.