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Search of human proteins with 119226220
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|119226220 membrane-spanning 4-domains, subfamily A, member
14 isoform 2 [Homo sapiens]
(662 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|119226220 membrane-spanning 4-domains, subfamily A, member 14... 1313 0.0
gi|119226217 membrane-spanning 4-domains, subfamily A, member 14... 1302 0.0
gi|44890059 involucrin [Homo sapiens] 71 4e-12
gi|221139761 zinc finger protein 853 [Homo sapiens] 64 3e-10
gi|95147555 microtubule-associated protein 1A [Homo sapiens] 63 8e-10
gi|148746195 trichohyalin [Homo sapiens] 60 5e-09
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 56 1e-07
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 56 1e-07
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 56 1e-07
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 56 1e-07
gi|214831008 membrane-spanning 4-domains, subfamily A, member 2 ... 54 4e-07
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 54 4e-07
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 54 4e-07
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 54 4e-07
gi|20070328 membrane-spanning 4-domains, subfamily A, member 4 i... 54 6e-07
gi|23110995 membrane-spanning 4-domains, subfamily A, member 4 i... 54 6e-07
gi|4503677 membrane-spanning 4-domains, subfamily A, member 2 is... 53 8e-07
gi|23110997 membrane-spanning 4-domains, subfamily A, member 5 [... 53 8e-07
gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithora... 53 1e-06
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 52 1e-06
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 52 1e-06
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 52 2e-06
gi|17017963 forkhead box P2 isoform I [Homo sapiens] 51 4e-06
gi|93141033 PAX interacting protein 1 [Homo sapiens] 51 4e-06
gi|48255931 hepatoma-derived growth factor-related protein 2 iso... 51 4e-06
gi|14249158 hepatoma-derived growth factor-related protein 2 iso... 51 4e-06
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 50 5e-06
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 50 5e-06
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 50 7e-06
gi|8923206 membrane-spanning 4-domains, subfamily A, member 12 [... 50 9e-06
>gi|119226220 membrane-spanning 4-domains, subfamily A, member 14
isoform 2 [Homo sapiens]
Length = 662
Score = 1313 bits (3397), Expect = 0.0
Identities = 662/662 (100%), Positives = 662/662 (100%)
Query: 1 MESTSQDRRATHVITIKPNETVLTAFPYRPHSSLLDFLKGEPRVLGATQILLALIIVGFG 60
MESTSQDRRATHVITIKPNETVLTAFPYRPHSSLLDFLKGEPRVLGATQILLALIIVGFG
Sbjct: 1 MESTSQDRRATHVITIKPNETVLTAFPYRPHSSLLDFLKGEPRVLGATQILLALIIVGFG 60
Query: 61 TIFALNYIGFSQRLPLVVLTGYPFWGALIGQGVTGMNVISSLVAITGITFTILSYRHQDK 120
TIFALNYIGFSQRLPLVVLTGYPFWGALIGQGVTGMNVISSLVAITGITFTILSYRHQDK
Sbjct: 61 TIFALNYIGFSQRLPLVVLTGYPFWGALIGQGVTGMNVISSLVAITGITFTILSYRHQDK 120
Query: 121 YCQMPSFEEICVFSRTLFIVLFFLPSDVTQNSEQPAPEENDQLQFVLQEEFSSDDSTTNA 180
YCQMPSFEEICVFSRTLFIVLFFLPSDVTQNSEQPAPEENDQLQFVLQEEFSSDDSTTNA
Sbjct: 121 YCQMPSFEEICVFSRTLFIVLFFLPSDVTQNSEQPAPEENDQLQFVLQEEFSSDDSTTNA 180
Query: 181 QSVIFGGYAFFKLTLSRSPLVSQPGNKGREFVPDEQKQSILPSPKFSEEEIEPLPPTLEK 240
QSVIFGGYAFFKLTLSRSPLVSQPGNKGREFVPDEQKQSILPSPKFSEEEIEPLPPTLEK
Sbjct: 181 QSVIFGGYAFFKLTLSRSPLVSQPGNKGREFVPDEQKQSILPSPKFSEEEIEPLPPTLEK 240
Query: 241 KPSENMSIQLDSTFKQMKDEDLQSAIVQPSQMQTKLLQDQAASLQVFPSHSALKLEDISP 300
KPSENMSIQLDSTFKQMKDEDLQSAIVQPSQMQTKLLQDQAASLQVFPSHSALKLEDISP
Sbjct: 241 KPSENMSIQLDSTFKQMKDEDLQSAIVQPSQMQTKLLQDQAASLQVFPSHSALKLEDISP 300
Query: 301 EDLPSQALPVEGLSEQTMPSKSTSSHVKQSSNLTANDLPPQGILSQDTSSQDMLFHDMTS 360
EDLPSQALPVEGLSEQTMPSKSTSSHVKQSSNLTANDLPPQGILSQDTSSQDMLFHDMTS
Sbjct: 301 EDLPSQALPVEGLSEQTMPSKSTSSHVKQSSNLTANDLPPQGILSQDTSSQDMLFHDMTS 360
Query: 361 QDMQSLDMLSQDTPSHAMPPQDIPSQDMLSQALSAHAILPEASTSHIVQFPEIQHLLQQP 420
QDMQSLDMLSQDTPSHAMPPQDIPSQDMLSQALSAHAILPEASTSHIVQFPEIQHLLQQP
Sbjct: 361 QDMQSLDMLSQDTPSHAMPPQDIPSQDMLSQALSAHAILPEASTSHIVQFPEIQHLLQQP 420
Query: 421 PDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQQTKALQY 480
PDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQQTKALQY
Sbjct: 421 PDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQQTKALQY 480
Query: 481 LRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQT 540
LRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQT
Sbjct: 481 LRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQT 540
Query: 541 KEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSP 600
KEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSP
Sbjct: 541 KEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSP 600
Query: 601 KGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQFHKGNLQAGQPRTVNLLAKNPL 660
KGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQFHKGNLQAGQPRTVNLLAKNPL
Sbjct: 601 KGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQFHKGNLQAGQPRTVNLLAKNPL 660
Query: 661 TG 662
TG
Sbjct: 661 TG 662
>gi|119226217 membrane-spanning 4-domains, subfamily A, member 14
isoform 1 [Homo sapiens]
Length = 679
Score = 1302 bits (3369), Expect = 0.0
Identities = 662/679 (97%), Positives = 662/679 (97%), Gaps = 17/679 (2%)
Query: 1 MESTSQDRRATHVITIKPNETVLTAFPYRPHSSLLDFLKGEPRVLGATQILLALIIVGFG 60
MESTSQDRRATHVITIKPNETVLTAFPYRPHSSLLDFLKGEPRVLGATQILLALIIVGFG
Sbjct: 1 MESTSQDRRATHVITIKPNETVLTAFPYRPHSSLLDFLKGEPRVLGATQILLALIIVGFG 60
Query: 61 TIFALNYIGFSQRLPLVVLTGYPFWGALI-----------------GQGVTGMNVISSLV 103
TIFALNYIGFSQRLPLVVLTGYPFWGALI GQGVTGMNVISSLV
Sbjct: 61 TIFALNYIGFSQRLPLVVLTGYPFWGALIFILTGYLTVTDKKSKLLGQGVTGMNVISSLV 120
Query: 104 AITGITFTILSYRHQDKYCQMPSFEEICVFSRTLFIVLFFLPSDVTQNSEQPAPEENDQL 163
AITGITFTILSYRHQDKYCQMPSFEEICVFSRTLFIVLFFLPSDVTQNSEQPAPEENDQL
Sbjct: 121 AITGITFTILSYRHQDKYCQMPSFEEICVFSRTLFIVLFFLPSDVTQNSEQPAPEENDQL 180
Query: 164 QFVLQEEFSSDDSTTNAQSVIFGGYAFFKLTLSRSPLVSQPGNKGREFVPDEQKQSILPS 223
QFVLQEEFSSDDSTTNAQSVIFGGYAFFKLTLSRSPLVSQPGNKGREFVPDEQKQSILPS
Sbjct: 181 QFVLQEEFSSDDSTTNAQSVIFGGYAFFKLTLSRSPLVSQPGNKGREFVPDEQKQSILPS 240
Query: 224 PKFSEEEIEPLPPTLEKKPSENMSIQLDSTFKQMKDEDLQSAIVQPSQMQTKLLQDQAAS 283
PKFSEEEIEPLPPTLEKKPSENMSIQLDSTFKQMKDEDLQSAIVQPSQMQTKLLQDQAAS
Sbjct: 241 PKFSEEEIEPLPPTLEKKPSENMSIQLDSTFKQMKDEDLQSAIVQPSQMQTKLLQDQAAS 300
Query: 284 LQVFPSHSALKLEDISPEDLPSQALPVEGLSEQTMPSKSTSSHVKQSSNLTANDLPPQGI 343
LQVFPSHSALKLEDISPEDLPSQALPVEGLSEQTMPSKSTSSHVKQSSNLTANDLPPQGI
Sbjct: 301 LQVFPSHSALKLEDISPEDLPSQALPVEGLSEQTMPSKSTSSHVKQSSNLTANDLPPQGI 360
Query: 344 LSQDTSSQDMLFHDMTSQDMQSLDMLSQDTPSHAMPPQDIPSQDMLSQALSAHAILPEAS 403
LSQDTSSQDMLFHDMTSQDMQSLDMLSQDTPSHAMPPQDIPSQDMLSQALSAHAILPEAS
Sbjct: 361 LSQDTSSQDMLFHDMTSQDMQSLDMLSQDTPSHAMPPQDIPSQDMLSQALSAHAILPEAS 420
Query: 404 TSHIVQFPEIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRR 463
TSHIVQFPEIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRR
Sbjct: 421 TSHIVQFPEIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRR 480
Query: 464 KSSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDW 523
KSSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDW
Sbjct: 481 KSSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDW 540
Query: 524 LSPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQ 583
LSPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQ
Sbjct: 541 LSPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQ 600
Query: 584 TQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQFHKGN 643
TQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQFHKGN
Sbjct: 601 TQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQFHKGN 660
Query: 644 LQAGQPRTVNLLAKNPLTG 662
LQAGQPRTVNLLAKNPLTG
Sbjct: 661 LQAGQPRTVNLLAKNPLTG 679
>gi|44890059 involucrin [Homo sapiens]
Length = 585
Score = 70.9 bits (172), Expect = 4e-12
Identities = 112/488 (22%), Positives = 199/488 (40%), Gaps = 59/488 (12%)
Query: 193 LTLSRSPLVSQPGNKGREFVPDEQKQSILPSPKFSEEEIE---PLPPTLEKKPSENMSIQ 249
L ++ SP +SQ E +++ P +E+++ PLPP +K P E + ++
Sbjct: 7 LPVTLSPALSQ-----------ELLKTVPPPVNTHQEQMKQPTPLPPPCQKVPVE-LPVE 54
Query: 250 LDSTFKQMKDEDLQSAIVQPSQMQTKLLQDQAASLQVFPSHSALKLEDISPEDLPSQALP 309
+ S ++ ++ Q + Q K Q+Q Q + H E+ + P Q L
Sbjct: 55 VPSKQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQH-----EEYQKAENPEQQLK 109
Query: 310 VEGLSEQTMPSKSTSSHVKQSSNLTANDLPPQGILSQDTS---SQDMLFHDMTSQDMQSL 366
E+T + + +++ L L Q ++ +D ++ L ++ Q L
Sbjct: 110 ----QEKTQRDQQLNKQLEEEKKLLDQQLD-QELVKRDEQLGMKKEQLL-ELPEQQEGHL 163
Query: 367 DMLSQDTPSHAMPPQDIPSQDMLSQALSAHAILPEASTSHIVQFPEIQHLLQQPPDLQPE 426
L Q P Q Q L + LPE + + PE Q + P+ Q
Sbjct: 164 KHLEQQEGQLKHPEQQ-EGQLELPEQQEGQLELPEQQEGQL-ELPEQQEGQLELPEQQEG 221
Query: 427 NTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSL 486
E QQ Q+ + +E +++ + + EL ++ + L Q L+
Sbjct: 222 QLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMG 281
Query: 487 DVQAKGQKSSKRHSLDQQSKGWQSPKQ-----KSLDQQIKDWLSPKRHSVDKQAQLNQTK 541
++ Q+ + LDQQ K + P+Q K L+QQ +H ++ QL Q +
Sbjct: 282 QLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQE----GQPKHLEQQEGQLEQLE 337
Query: 542 EQ---LPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKK 598
EQ L + ++ Q + ++ EGQ G + Q +Q K+Q Q + E++ Q K
Sbjct: 338 EQEGQLKHLEQQEGQLEHLEHQEGQL--GLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKH 395
Query: 599 --SPKGQFQN-VQAEGQQAQVEKVPKLLCQDS------ESQIQQYQFWQFHKGNL----- 644
+GQ ++ VQ EGQ Q E+ + L Q E Q Q + + +G L
Sbjct: 396 LVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQ 455
Query: 645 QAGQPRTV 652
Q GQP+ +
Sbjct: 456 QVGQPKNL 463
Score = 62.0 bits (149), Expect = 2e-09
Identities = 98/430 (22%), Positives = 174/430 (40%), Gaps = 74/430 (17%)
Query: 215 EQKQSILPSPKFSEEEIEPLPPTLEKKPSENMSIQLDSTFKQMKDEDLQSAIVQPSQMQT 274
EQ++ L P+ E ++E + +++ +S Q + K ++ ++ Q + + Q
Sbjct: 227 EQQEGQLELPQQQEGQLEL---SEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQL 283
Query: 275 KLLQDQAASLQVFPSHSALKLEDISPEDLPSQALPVEGLSEQTMPSKSTSSHVKQSSNLT 334
K L+ Q L+ L ++ PE LP Q + G + + H++Q
Sbjct: 284 KYLEQQEGQLK------HLDQQEKQPE-LPEQQM---GQLKHLEQQEGQPKHLEQQ---- 329
Query: 335 ANDLPPQGILSQDTSSQDMLFHDMTSQDMQSLDMLSQDTPSHAMPPQDIPSQDMLS--QA 392
+G L Q + L H Q L+ L +P Q + L Q
Sbjct: 330 ------EGQLEQLEEQEGQLKH--LEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQG 381
Query: 393 LSAHAILPEASTSHIVQFP-EIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEET 451
H E H+VQ +++HL+QQ L E Q +Q+
Sbjct: 382 QPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQL-----EQQERQV---------------- 420
Query: 452 KEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSP 511
E L ++ +H L +Q L++L + ++ Q+ + +L+Q+ K + P
Sbjct: 421 ------EHLEQQVGQLKH-LEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELP 473
Query: 512 KQKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKD 571
+Q+ + Q+K H ++AQL ++Q+ + +QQ K ++PE Q DGQ+K
Sbjct: 474 EQQ--EGQVK-------HLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQ--DGQLKH 522
Query: 572 QQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQI 631
+ + Q + Q Q E QP GQ Q++ Q A K LL + + Q
Sbjct: 523 LEQQEGQLKDLEQQKGQLE-QPV--FAPAPGQVQDI----QPALPTKGEVLLPVEHQQQK 575
Query: 632 QQYQFWQFHK 641
Q+ Q+ HK
Sbjct: 576 QEVQWPPKHK 585
Score = 45.1 bits (105), Expect = 2e-04
Identities = 84/429 (19%), Positives = 172/429 (40%), Gaps = 55/429 (12%)
Query: 228 EEEIEPLPPTLEK---KPSENMSIQLDSTFKQMKDEDLQSAIVQPSQMQTKLLQDQAASL 284
EEE + L L++ K E + ++ + + + ++ ++ + Q K + Q L
Sbjct: 124 EEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQL 183
Query: 285 QVFPSHSALKLEDISPEDLPSQA-LPVEGLSEQTMPSKSTSSHVKQSSNLTANDLPPQGI 343
++ P +LE PE Q LP + + +P + +LP Q
Sbjct: 184 EL-PEQQEGQLE--LPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQE 240
Query: 344 LSQDTSSQDMLFHDMTSQDMQSLDMLSQDTPSHAMPPQDIPSQDMLSQA------LSAHA 397
+ S Q +++ Q L L +P + + L Q L
Sbjct: 241 GQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQE 300
Query: 398 ILPEASTSHIVQFPEIQHLLQQPPDL-----QPENTEPQNQQILQMSYQDIRSEVMEETK 452
PE + Q ++ QP L Q E E Q Q+ + Q+ + E +E +
Sbjct: 301 KQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQE 360
Query: 453 --------EWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQ 504
+ ++L +++ +H L ++ L++L VQ +GQ +H + Q+
Sbjct: 361 GQLGLPEQQVLQLKQLEKQQGQPKH-LEEEEGQLKHL------VQQEGQL---KHLVQQE 410
Query: 505 SKGWQSPKQ-KSLDQQIKDWLSPKRHSVDKQAQLNQTKEQ-----LPDQQA--------E 550
+ Q +Q + L+QQ+ +H +++ QL ++Q +P+QQ E
Sbjct: 411 GQLEQQERQVEHLEQQV----GQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQE 466
Query: 551 DQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNV-QA 609
++Q + + EGQ K + ++ Q + + Q + + +++ + + GQ +++ Q
Sbjct: 467 EKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQ 526
Query: 610 EGQQAQVEK 618
EGQ +E+
Sbjct: 527 EGQLKDLEQ 535
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 64.3 bits (155), Expect = 3e-10
Identities = 63/233 (27%), Positives = 109/233 (46%), Gaps = 26/233 (11%)
Query: 418 QQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQQTKA 477
Q+ + Q N+ PQ + S SE+ EET+ + E +L + + Q +
Sbjct: 52 QEEEEPQERNSSPQRPAV---SAPVGASEIAEETRPGQRELQLQQLEQQPEPQQQPQHEQ 108
Query: 478 LQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIK-----DWLSPKRHSVD 532
LQ + H L++Q + Q+ ++ Q + QS + L +++ L P++ V
Sbjct: 109 LQQPQPH-LELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQ--VQ 165
Query: 533 KQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQ 592
+Q +L Q +EQL QQA++QQ +Q + QV++QQ ++Q + Q Q + +
Sbjct: 166 EQQRLQQQQEQLQTQQAQEQQVLQQQ----EQLQQQVQEQQLLQQQQEQLQQQQLLQQQE 221
Query: 593 PAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQFHKGNLQ 645
Q++ QFQ Q + QQ Q +LL + Q+QQ Q Q + LQ
Sbjct: 222 QLQQQ-----QFQQQQEQLQQQQ-----QLLLLQQQGQLQQ-QLLQQQQAQLQ 263
Score = 62.4 bits (150), Expect = 1e-09
Identities = 62/238 (26%), Positives = 110/238 (46%), Gaps = 22/238 (9%)
Query: 412 EIQHLLQQPPDLQPENTEPQNQQILQ-MSYQDIRSEVMEETKEWKSEEELHRRKSSRRHS 470
++Q L QQP Q +PQ++Q+ Q + +++ + ++ ++ S+ + + +S
Sbjct: 90 QLQQLEQQPEPQQ----QPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQE 145
Query: 471 LNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHS 530
L + LQ + + Q + Q+ ++ L QQ + Q+ Q++ +QQ+ +
Sbjct: 146 LKPE---LQLMHQQQ---QLQPQQVQEQQRLQQQQEQLQT--QQAQEQQVLQQQEQLQQQ 197
Query: 531 VDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTE 590
V +Q L Q +EQL QQ QQ + +Q + Q + Q++ QQ + Q Q Q +
Sbjct: 198 VQEQQLLQQQQEQLQQQQLLQQQEQLQQ-QQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQ 256
Query: 591 DQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQFHKGNLQAGQ 648
Q A Q Q E QQAQ+++ L Q+ Q QQ Q Q + LQ Q
Sbjct: 257 QQQA--------QLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQ 306
Score = 60.8 bits (146), Expect = 4e-09
Identities = 72/292 (24%), Positives = 119/292 (40%), Gaps = 30/292 (10%)
Query: 344 LSQDTSSQDMLFHDMTSQDMQSLDMLSQDTPSHAMPPQDIPSQDMLSQALSAHAILPEAS 403
L Q Q H+ Q L++ Q P QD Q LSQ S
Sbjct: 94 LEQQPEPQQQPQHEQLQQPQPHLELQQQ-------PQQD--GQQQLSQLQQEK----HQS 140
Query: 404 TSHIVQFPEIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRR 463
H PE+Q L+ Q LQP+ Q QQ LQ + ++++ +E + + +E+L ++
Sbjct: 141 VHHQELKPELQ-LMHQQQQLQPQQV--QEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQ 197
Query: 464 KSSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDW 523
++ QQ + Q + + Q ++ L QQ + +Q L QQ+
Sbjct: 198 VQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQ- 256
Query: 524 LSPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQ 583
+QAQL Q + L QQA+ QQ Q E + Q + Q +EQ ++Q
Sbjct: 257 --------QQQAQLQQ--QLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQ 306
Query: 584 TQDQQTEDQPAQE---KKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQ 632
Q E + +E + P + E Q+ ++E+ +L Q + Q+Q
Sbjct: 307 LQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQ 358
Score = 57.4 bits (137), Expect = 4e-08
Identities = 73/342 (21%), Positives = 146/342 (42%), Gaps = 30/342 (8%)
Query: 297 DISPEDLPSQA-LPVEGLSEQTMPSKSTSSHVKQSS--NLTANDLPPQGILSQDTSSQDM 353
+I+ E P Q L ++ L +Q P + Q +L P Q Q + Q
Sbjct: 77 EIAEETRPGQRELQLQQLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQE 136
Query: 354 LFHDMTSQDMQ-SLDMLSQDTPSHAMPPQDIPSQDMLSQALSAHAILPEASTSHIVQFPE 412
+ Q+++ L ++ Q + PQ + Q L Q + Q +
Sbjct: 137 KHQSVHHQELKPELQLMHQQ---QQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQ 193
Query: 413 IQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELH--RRKSSRRHS 470
+Q +Q+ LQ + + Q QQ+LQ Q + + ++ ++ + +++L +++ +
Sbjct: 194 LQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQ 253
Query: 471 LNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLS----- 525
L QQ +A L++ L+ Q Q ++ L QQ + Q +Q+ L QQ ++ L
Sbjct: 254 LLQQQQA--QLQQQLLEQQ---QAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQ 308
Query: 526 --PKRHSVDKQAQLNQT-----KEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQ 578
P +++ +L EQ +QQ ++ + + E + + + Q+K Q+ ++
Sbjct: 309 PPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQLKLQEELQQL 368
Query: 579 NSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVP 620
+ + Q QQ E Q Q + +P + A+ Q+ Q+E P
Sbjct: 369 EQQLEQQQQQLEQQEVQLELTP----VELGAQQQEVQLELTP 406
>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
Length = 2803
Score = 63.2 bits (152), Expect = 8e-10
Identities = 100/455 (21%), Positives = 201/455 (44%), Gaps = 57/455 (12%)
Query: 214 DEQKQSILPSPKFSEEEIEPLP----------------PTLEKKPSENMSIQLDSTFKQM 257
D + S+L P EP P P + + ++++S+ +S K+
Sbjct: 1149 DAESLSVLSVPSPDTANQEPTPKSPCGLTEQYLHKDRWPEVSPEDTQSLSLSEESPSKET 1208
Query: 258 KDEDLQSAIVQPSQMQTKLLQDQAASLQVFPSHSALKLEDISPEDLPSQALPVEGLSEQT 317
D+ S + P + T LQ +L ++ ED S P ++P + +
Sbjct: 1209 S-LDVSSKQLSPESLGT--LQFGELNLGKEEMGHLMQAEDTSHHTAP-MSVPEPHAATAS 1264
Query: 318 MPSKSTSSHVKQSSNLTANDLP---PQGILSQDTSSQD--MLFHDMTSQDMQSLDMLSQD 372
P+ T+ + Q+ ++T + L P S T S + L +TS D +L+ D
Sbjct: 1265 PPTDGTTRYSAQT-DITDDSLDRKSPASSFSHSTPSGNGKYLPGAITSPDEH---ILTPD 1320
Query: 373 TPSHAMPPQDIPSQDMLSQALSAHAILP--EASTSHIVQFPEIQHLLQQPPDLQPEN--- 427
+ S + P+ +P + A+ +P + TS + PE + + Q D E+
Sbjct: 1321 S-SFSKSPESLPGPALEDIAIKWEDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLEHKEV 1379
Query: 428 TEPQNQQILQMSYQ-DIRSEVMEETKEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSL 486
EP++ I Q +++E +++ K+ E+ R + +L Q+ KAL+ +
Sbjct: 1380 VEPKDTAIYQKDEALHVKNEAVKQQD--KALEQKGRDLEQKDTALEQKDKALEPKDK--- 1434
Query: 487 DVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQLPD 546
D++ K + ++ + ++ K +L+Q+ K L PK ++++ ++ + KE++P+
Sbjct: 1435 DLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKA-LEPKDKDLEQKDRVLEQKEKIPE 1493
Query: 547 Q--QAEDQQAKGEQYPEGQSKDGQVKD---QQTDKEQNSKKQTQDQ-----QTEDQPAQE 596
+ +A DQ+ + ++ + ++KD +QTDK K Q Q+Q + +DQ ++
Sbjct: 1494 EKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQ 1553
Query: 597 KKSPKGQ-----FQNVQAEGQQAQVEKVPKLLCQD 626
K GQ QN+QA + Q ++ L+ +D
Sbjct: 1554 KYWALGQKDEALEQNIQALEENHQTQEQESLVQED 1588
Score = 30.8 bits (68), Expect = 4.2
Identities = 29/163 (17%), Positives = 67/163 (41%), Gaps = 2/163 (1%)
Query: 462 RRKSSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIK 521
++++ + SL TK +V +G K ++ + +K + K+ S K
Sbjct: 314 KQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTEKKAKESSEKPPEK 373
Query: 522 DWLSPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSK 581
P+R + L K +L + + K + + KD + K+ + ++++ K
Sbjct: 374 P-AKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKERKELKK 432
Query: 582 KQTQDQQTEDQPAQEK-KSPKGQFQNVQAEGQQAQVEKVPKLL 623
+ + ++ +D +EK K K + + + + +V K L
Sbjct: 433 DEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTL 475
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 60.5 bits (145), Expect = 5e-09
Identities = 46/211 (21%), Positives = 105/211 (49%), Gaps = 14/211 (6%)
Query: 423 LQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQQTKALQYLR 482
L+ E E + +Q L+ Q R + + ++ + E++L R + RR QQ + Q LR
Sbjct: 364 LRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE---QQLRREQQLR 420
Query: 483 RHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTKE 542
R Q + ++ +RH + + + + K ++ +DWL KR ++ + + K+
Sbjct: 421 REQ---QLRREQEEERHEQKHEQER-REQRLKREQEERRDWL--KREEETERHEQERRKQ 474
Query: 543 QLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKG 602
QL Q E+++ + + E + ++ QQ +EQ +++ ++++ + QE++
Sbjct: 475 QLKRDQEEERRERWLKLEEEERRE-----QQERREQQLRREQEERREQRLKRQEEEERLQ 529
Query: 603 QFQNVQAEGQQAQVEKVPKLLCQDSESQIQQ 633
Q + + ++ Q E+ +LL ++ E +++Q
Sbjct: 530 QRLRSEQQLRREQEERREQLLKREEEKRLEQ 560
Score = 52.8 bits (125), Expect = 1e-06
Identities = 50/242 (20%), Positives = 113/242 (46%), Gaps = 18/242 (7%)
Query: 412 EIQHLLQQPPDLQPENTEPQ-NQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHS 470
E + L+Q D + E Q ++Q +++ +V + +E K EE + + R
Sbjct: 1403 EREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRK 1462
Query: 471 LNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHS 530
++ + LQ L Q + +K + ++Q Q +K +Q+++ P+R
Sbjct: 1463 FREEEQLLQEREEQQLHRQERDRKFLE----EEQQLRRQERDRKFREQELRSQ-EPERKF 1517
Query: 531 VDKQAQLNQTKEQ---LPDQQAEDQQAKGEQ--------YPEGQSKDGQVKDQQTDKEQN 579
++++ QL++ + Q L ++Q +Q +G+Q + E + + ++QQ +++
Sbjct: 1518 LEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQER 1577
Query: 580 SKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQF 639
+K ++Q + QE+K + + Q + EGQQ Q+ + ++ E +Q+ + Q
Sbjct: 1578 DRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQ-QLRQERDRKFREDEQLLQEREEQQL 1636
Query: 640 HK 641
H+
Sbjct: 1637 HR 1638
Score = 50.4 bits (119), Expect = 5e-06
Identities = 52/246 (21%), Positives = 109/246 (44%), Gaps = 8/246 (3%)
Query: 408 VQFPEIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSR 467
+QF E + LQ+ Q E LQ + RS+ ++W+ + L + R
Sbjct: 831 LQFLEEEEQLQRRERAQQLQEEEDG---LQEDQERRRSQEQRRDQKWRWQ--LEEERKRR 885
Query: 468 RHSLNQQTKALQYLRRHS--LDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLS 525
RH+L + + LR+ L + + + +R +Q + Q +++ L Q+ + L
Sbjct: 886 RHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLR 945
Query: 526 PKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQ 585
+R +Q + Q ++ QQ E +Q GE+ + + ++ + K ++ ++ Q ++Q
Sbjct: 946 EEREKRRRQERERQYRKDKKLQQKE-EQLLGEEPEKRRRQEREKKYREEEELQQEEEQLL 1004
Query: 586 DQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQFHKGNLQ 645
++ E + QE + + +Q E +Q E+ K Q+ E Q ++ + Q + L
Sbjct: 1005 REEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLL 1064
Query: 646 AGQPRT 651
+ T
Sbjct: 1065 GEERET 1070
Score = 50.4 bits (119), Expect = 5e-06
Identities = 49/250 (19%), Positives = 110/250 (44%), Gaps = 31/250 (12%)
Query: 409 QFPEIQHLLQQPPDLQPENTEPQNQQILQMSYQD-----------IRSEV----MEETKE 453
Q+ E + + Q+ L E E + +Q L+ Y++ +R E E ++
Sbjct: 1139 QYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQ 1198
Query: 454 WKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQ 513
++ EEEL R+K +R+ Q R L Q + +K + KG ++ +
Sbjct: 1199 YREEEELQRQKRKQRYRDEDQ--------RSDLKWQWEPEKENAVRDNKVYCKGRENEQF 1250
Query: 514 KSL-DQQIKDWLSPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQ 572
+ L D Q++D ++ D Q L + +E+ +Q+ Q + +PE + + +++
Sbjct: 1251 RQLEDSQLRD----RQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLE---REE 1303
Query: 573 QTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQ 632
Q + ++ +K +++Q + +EK+ + + + E Q Q + L Q+ + + +
Sbjct: 1304 QKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFR 1363
Query: 633 QYQFWQFHKG 642
+ + +G
Sbjct: 1364 EEELRHQEQG 1373
Score = 50.1 bits (118), Expect = 7e-06
Identities = 53/264 (20%), Positives = 116/264 (43%), Gaps = 33/264 (12%)
Query: 412 EIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSL 471
E Q L ++ +LQ E E + +Q + Y++ E +++ +E EE +R+ R
Sbjct: 902 EQQLLQEEEEELQREEREKRRRQEQERQYRE--EEQLQQEEEQLLREEREKRRRQERERQ 959
Query: 472 NQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSV 531
++ K LQ + Q G++ KR +++ K + + + ++Q+ KR
Sbjct: 960 YRKDKKLQ-----QKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQ 1014
Query: 532 D------KQAQLNQTKEQL--------------------PDQQAEDQQAKGEQYPEGQSK 565
+ K+ +L Q +EQL + Q E++Q GE+ + +
Sbjct: 1015 EWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQ 1074
Query: 566 DGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQ 625
+ + + ++ ++ Q ++Q ++ E + QE++ + + +Q E +Q E+ K Q
Sbjct: 1075 ELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQ 1134
Query: 626 DSESQIQQYQFWQFHKGNLQAGQP 649
+ E Q ++ + Q + L +P
Sbjct: 1135 ELERQYREEEEVQQEEEQLLREEP 1158
Score = 49.7 bits (117), Expect = 9e-06
Identities = 48/229 (20%), Positives = 110/229 (48%), Gaps = 21/229 (9%)
Query: 412 EIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSL 471
E Q ++ + + + E + QQ+ + + ++ E +E + E++L R + R
Sbjct: 316 EQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERRE- 374
Query: 472 NQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSV 531
QQ + Q LRR + Q + ++ +R +QQ + Q Q +QQ++ +R
Sbjct: 375 -QQLRREQQLRR---EQQLRREQQLRR---EQQLRREQ---QLRREQQLRREQQLRREQQ 424
Query: 532 DKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQ---DQQ 588
++ Q + EQ +Q+ +Q+ K EQ + +D ++++T++ + +++ Q DQ+
Sbjct: 425 LRREQEEERHEQKHEQERREQRLKREQ---EERRDWLKREEETERHEQERRKQQLKRDQE 481
Query: 589 TEDQ----PAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQ 633
E + +E++ + Q + Q ++ + + +L Q+ E ++QQ
Sbjct: 482 EERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQ 530
Score = 49.7 bits (117), Expect = 9e-06
Identities = 47/244 (19%), Positives = 117/244 (47%), Gaps = 24/244 (9%)
Query: 414 QHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQ 473
Q L ++ + + + + Q ++ + Q +RSE ++ + E+L +R+ +R +
Sbjct: 505 QQLRREQEERREQRLKRQEEE--ERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQER 562
Query: 474 QTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDK 533
+ + L+ + D K ++ ++ L ++ +++ L+Q++ KR V++
Sbjct: 563 REQRLKREQEERRDQLLKREEERRQQRLKRE-------QEERLEQRL------KREEVER 609
Query: 534 QAQLNQTKEQL----PDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQT 589
Q + +++L P+++ Q K E+ E + + + ++QQ +EQ K++ ++++
Sbjct: 610 LEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLR-REQQERREQRLKREEEEERL 668
Query: 590 EDQPAQEKKSPKGQFQNVQAEGQQAQ---VEKVPKLLCQDSESQIQQYQFWQFHKGNLQA 646
E + +E + + + + + E +QA+ ++PK Q ES+ Q + + Q
Sbjct: 669 EQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQ-LESEADARQSKVYSRPRKQE 727
Query: 647 GQPR 650
GQ R
Sbjct: 728 GQRR 731
Score = 49.3 bits (116), Expect = 1e-05
Identities = 46/264 (17%), Positives = 116/264 (43%), Gaps = 39/264 (14%)
Query: 411 PEIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRK------ 464
P + L ++P + + + Q +++ + Q + E +E+ + +EEL R++
Sbjct: 124 PRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQER 183
Query: 465 -----------SSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQ 513
S + H + Q RR L+++ KG++ ++ ++Q + +Q ++
Sbjct: 184 EERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEE 243
Query: 514 KSLDQQI----KDWLSPKRHSVDKQAQLNQTKEQL--------------PDQQAE----D 551
K ++ K+ + +Q +L + +EQL +QQ + +
Sbjct: 244 KEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRRE 303
Query: 552 QQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEG 611
QQ + +Q E + + + ++QQ +EQ +++ Q + E + +E++ + Q + + +
Sbjct: 304 QQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQ 363
Query: 612 QQAQVEKVPKLLCQDSESQIQQYQ 635
+ + E+ + E Q+++ Q
Sbjct: 364 LRREQEEERREQQLRREQQLRREQ 387
Score = 48.9 bits (115), Expect = 1e-05
Identities = 52/242 (21%), Positives = 108/242 (44%), Gaps = 30/242 (12%)
Query: 409 QFPEIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRR--KSS 466
Q+ E + L Q+ L E E + +Q L+ Y+ +E + + EE+L R +
Sbjct: 1049 QYREEEELQQEEEQLLGEERETRRRQELERQYR-------KEEELQQEEEQLLREEPEKR 1101
Query: 467 RRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSP 526
RR +Q + + L++ + + ++ +R L++Q + +++ + Q+ + L
Sbjct: 1102 RRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYR-----EEEEVQQEEEQLLRE 1156
Query: 527 KRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQD 586
+ +Q Q +E+ QQ E+Q + EQ Q ++ Q ++++ + Q K++ +D
Sbjct: 1157 EPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRD 1216
Query: 587 QQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQFHKGNLQA 646
EDQ + K Q E ++ + K+ C+ E++ QF Q L+
Sbjct: 1217 ---EDQRSDLK---------WQWEPEKENAVRDNKVYCKGRENE----QFRQLEDSQLRD 1260
Query: 647 GQ 648
Q
Sbjct: 1261 RQ 1262
Score = 48.9 bits (115), Expect = 1e-05
Identities = 47/253 (18%), Positives = 117/253 (46%), Gaps = 25/253 (9%)
Query: 398 ILPEASTSHIVQFPEIQHLLQQPPDLQPENTEPQ-----------NQQILQMSY-QDIRS 445
+L E + + + L++ P L+ + E Q +Q+LQ Q +R
Sbjct: 1627 LLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRR 1686
Query: 446 EVMEETKEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQS 505
+ E ++++ EE+ RR+ R L ++ Q LRR L+ + + ++ R +Q+
Sbjct: 1687 Q--ERDRKFREEEQQLRRQERERKFLQEE----QQLRRQELERKFR-EEEQLRQETEQEQ 1739
Query: 506 KGWQSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSK 565
Q +K L++ + L P+R ++Q Q +++ ++ + +Q + EQ Q
Sbjct: 1740 LRRQERYRKILEE---EQLRPER---EEQQLRRQERDRKFREEEQLRQEREEQQLRSQES 1793
Query: 566 DGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQ 625
D + ++++ +++ ++Q + QQ + + E++ + + Q + ++ + + +
Sbjct: 1794 DRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFAT 1853
Query: 626 DSESQIQQYQFWQ 638
+S+ ++ + WQ
Sbjct: 1854 QEKSRREEQELWQ 1866
Score = 48.5 bits (114), Expect = 2e-05
Identities = 40/201 (19%), Positives = 94/201 (46%), Gaps = 11/201 (5%)
Query: 416 LLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQQT 475
L ++ LQ E EPQ Q+ LQ + +R +E + + EEE +++ R QQ
Sbjct: 253 LRKEEEKLQEE--EPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRR----EQQL 306
Query: 476 KALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQA 535
+ Q R + + Q+ + +++ + + +++ +QQ++ +R ++Q
Sbjct: 307 RRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERR--EQQL 364
Query: 536 QLNQTKEQLPDQQAEDQQAKGEQYPEGQS---KDGQVKDQQTDKEQNSKKQTQDQQTEDQ 592
+ Q +E+ Q +QQ + EQ + ++ Q++ +Q + + ++ Q + E Q
Sbjct: 365 RREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 424
Query: 593 PAQEKKSPKGQFQNVQAEGQQ 613
+E++ + + ++ Q +Q
Sbjct: 425 LRREQEEERHEQKHEQERREQ 445
Score = 45.8 bits (107), Expect = 1e-04
Identities = 38/210 (18%), Positives = 97/210 (46%), Gaps = 12/210 (5%)
Query: 422 DLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQQTKALQYL 481
+L+ E E + QQ Q +R + EE +E + E RR+ R ++ + Q
Sbjct: 285 ELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEE----RREQQERREQQEERREQQLR 340
Query: 482 RRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTK 541
R + + ++ + +QQ + Q +++ +QQ++ + + ++ QL + +
Sbjct: 341 REQEERREQQLRREQEEERREQQLRREQEEERR--EQQLR-----REQQLRREQQLRREQ 393
Query: 542 EQLPDQQ-AEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSP 600
+ +QQ +QQ + EQ + + + + + ++E+ +Q +Q+ +Q + ++
Sbjct: 394 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEE 453
Query: 601 KGQFQNVQAEGQQAQVEKVPKLLCQDSESQ 630
+ + + E ++ + E+ + L +D E +
Sbjct: 454 RRDWLKREEETERHEQERRKQQLKRDQEEE 483
Score = 45.8 bits (107), Expect = 1e-04
Identities = 49/227 (21%), Positives = 103/227 (45%), Gaps = 23/227 (10%)
Query: 409 QFPEIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRR 468
++ E + L Q+ L E E + +Q + Y+ + E+ +E EE+L R + +R
Sbjct: 989 KYREEEELQQEEEQLLREEREKRRRQEWERQYRK-KDELQQE------EEQLLREEREKR 1041
Query: 469 HSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKR 528
Q + QY L + + +R + +Q Q K++ L Q+ + L +
Sbjct: 1042 ---RLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEP 1098
Query: 529 HSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQ 588
+Q + Q +E+ QQ E+Q + E + K ++ + E+ +++ + QQ
Sbjct: 1099 EKRRRQERERQCREEEELQQEEEQLLREE----------REKRRRQELERQYREEEEVQQ 1148
Query: 589 TEDQPAQE--KKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQ 633
E+Q +E +K + + + E ++ Q E+ +LL ++ E + Q+
Sbjct: 1149 EEEQLLREEPEKRRRQELERQYREEEELQQEE-EQLLREEQEKRRQE 1194
Score = 45.1 bits (105), Expect = 2e-04
Identities = 53/261 (20%), Positives = 116/261 (44%), Gaps = 26/261 (9%)
Query: 412 EIQHLLQQPPDLQP-ENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHS 470
E++ L Q+ Q + EP+ ++ Q+ ++SE EE ++ + E R+ R
Sbjct: 606 EVERLEQEERREQRLKREEPEEERRQQL----LKSEEQEERRQQQLRREQQERREQRLKR 661
Query: 471 LNQQTKALQYLRRHSLDVQ-----AKGQKSSKRHSLDQQSKGWQSPKQKSLD-QQIKDWL 524
++ + Q L+R + + A+ ++ R + + WQ + D +Q K +
Sbjct: 662 EEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYS 721
Query: 525 SPKRHSVDKQAQLNQTKEQLPD---QQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSK 581
P++ ++ Q + K + + Q E+++A +Q E Q +D + Q +K + +
Sbjct: 722 RPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGR 781
Query: 582 KQ------TQDQQTEDQPAQEKKSPKGQFQNVQAEGQQ---AQVEKVPKLLCQDSESQIQ 632
++ ++Q+ A+E++ + +F + E +Q + E+ +L + E Q+Q
Sbjct: 782 QRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQ 841
Query: 633 ---QYQFWQFHKGNLQAGQPR 650
+ Q Q + LQ Q R
Sbjct: 842 RRERAQQLQEEEDGLQEDQER 862
Score = 44.3 bits (103), Expect = 4e-04
Identities = 50/234 (21%), Positives = 111/234 (47%), Gaps = 27/234 (11%)
Query: 409 QFPEIQHLLQQPP-DLQPENTEPQNQQILQMSYQDIRSEVMEETKEW--------KSEEE 459
+FP+ + L ++ +L+ + E + QQ + QD R EE KEW K EE+
Sbjct: 203 EFPDEEQLRRRELLELRRKGREEKQQQ--RRERQD-RVFQEEEEKEWRKRETVLRKEEEK 259
Query: 460 LHRRKSSRRHSLNQQTKAL-----QYLRRHSLDVQAKGQKSSKRHSL--DQQSKGWQSPK 512
L + R+ L ++ + L Q LRR + + + Q+ + L Q+ + + +
Sbjct: 260 LQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQE 319
Query: 513 QKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQLPDQQAED---QQAKGEQYPEGQS----K 565
++ Q+ ++ +R ++ Q + ++QL +Q E+ QQ + EQ E + +
Sbjct: 320 ERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRR 379
Query: 566 DGQVK-DQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEK 618
+ Q++ +QQ +EQ +++ Q ++ + +++ + Q + Q ++ + E+
Sbjct: 380 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEER 433
Score = 43.1 bits (100), Expect = 8e-04
Identities = 37/197 (18%), Positives = 97/197 (49%), Gaps = 19/197 (9%)
Query: 412 EIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSL 471
E++ ++ L+ E + Q ++ Q Y+ I E E+ + + E++L R++ R+
Sbjct: 1720 ELERKFREEEQLRQETEQEQLRR--QERYRKILEE--EQLRPEREEQQLRRQERDRKFRE 1775
Query: 472 NQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIK-DWLSPKRHS 530
+Q LR+ + Q + Q+S ++ ++Q + Q+ +QQ++ K
Sbjct: 1776 EEQ------LRQEREEQQLRSQESDRKFREEEQLR------QEREEQQLRPQQRDGKYRW 1823
Query: 531 VDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTE 590
++Q QL + +++L +Q D+Q + E+ Q K + + + +E+ ++Q ++++
Sbjct: 1824 EEEQLQLEEQEQRL--RQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLR 1881
Query: 591 DQPAQEKKSPKGQFQNV 607
++ + ++ + + + V
Sbjct: 1882 EEHIRRQQKEEQRHRQV 1898
Score = 41.6 bits (96), Expect = 0.002
Identities = 51/257 (19%), Positives = 115/257 (44%), Gaps = 31/257 (12%)
Query: 407 IVQFPEIQHLLQQPPD---LQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRR 463
++Q E Q L +Q D L+ E + ++ + Q++RS+ E K + E++LHR+
Sbjct: 1469 LLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPER-KFLEEEQQLHRQ 1527
Query: 464 KSSRR-----HSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQ 518
+ R+ L +Q + Q RR D + + ++ ++ +QQ + ++ L++
Sbjct: 1528 QRQRKFLQEEQQLRRQERGQQ--RRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEE 1585
Query: 519 QIKDWLSPKRHSVDKQAQLNQTKEQLPDQQAEDQ---------QAKGEQYPEGQSKDG-- 567
Q +R ++ + QL + + Q +Q D+ Q + EQ Q +D
Sbjct: 1586 QKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKF 1645
Query: 568 ---------QVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEK 618
Q ++QQ +++ K + ++Q ++ Q+ + + + + E Q + E+
Sbjct: 1646 LEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQER 1705
Query: 619 VPKLLCQDSESQIQQYQ 635
K L ++ + + Q+ +
Sbjct: 1706 ERKFLQEEQQLRRQELE 1722
Score = 38.5 bits (88), Expect = 0.020
Identities = 41/222 (18%), Positives = 98/222 (44%), Gaps = 20/222 (9%)
Query: 417 LQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQQTK 476
LQ+ L+ + Q +Q +++ E+ ++ + E++L R++ R+ L +Q
Sbjct: 1534 LQEEQQLRRQERGQQRRQDRDRKFRE-----EEQLRQEREEQQLSRQERDRKFRLEEQKV 1588
Query: 477 ALQYLRRHSLDVQAKGQKSSKRHSLDQQ--------SKGWQSPKQKSLDQQIKDWL---- 524
Q R ++ + + ++ + L Q+ + Q +++ L +Q +D
Sbjct: 1589 RRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEE 1648
Query: 525 SPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKD--QQTDKEQNSKK 582
P+ +++ QL +++ ++ + Q EQ Q +D + ++ QQ +++ +K
Sbjct: 1649 EPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERK 1708
Query: 583 QTQ-DQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLL 623
Q +QQ Q + K + Q + + Q + E+ K+L
Sbjct: 1709 FLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKIL 1750
Score = 35.4 bits (80), Expect = 0.17
Identities = 47/242 (19%), Positives = 101/242 (41%), Gaps = 36/242 (14%)
Query: 423 LQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQQTKALQYLR 482
LQ +P +Q +++ E+ +++ EE+ RR+ R L ++ Q LR
Sbjct: 1345 LQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEE----QQLR 1400
Query: 483 RHSLDVQAKGQKSSKRHSLDQQ-SKGWQSPKQKSLDQQIK------------DWLSPKRH 529
+ Q + + K +QQ S+ + K + +QQ++ L +RH
Sbjct: 1401 CQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERH 1460
Query: 530 -SVDKQAQLNQTKE--QLPDQQAEDQQAKGEQYPEGQSKDGQVKDQ-------------- 572
++ QL Q +E QL Q+ + + + EQ Q +D + ++Q
Sbjct: 1461 RKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEE 1520
Query: 573 --QTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQ 630
Q ++Q +K Q++Q + + ++ + + + + E Q Q + +L Q+ + +
Sbjct: 1521 EQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRK 1580
Query: 631 IQ 632
+
Sbjct: 1581 FR 1582
Score = 33.9 bits (76), Expect = 0.49
Identities = 21/78 (26%), Positives = 45/78 (57%), Gaps = 6/78 (7%)
Query: 565 KDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLC 624
K+ ++D++ +++Q + + +D+Q E++P Q ++ + + + AEG++ Q EK +L
Sbjct: 106 KESLLQDRRQEEDQR-RFEPRDRQLEEEPGQRRRQKRQEQERELAEGEE-QSEKQERLEQ 163
Query: 625 QD----SESQIQQYQFWQ 638
+D E +Q Q WQ
Sbjct: 164 RDRQRRDEELWRQRQEWQ 181
Score = 33.5 bits (75), Expect = 0.64
Identities = 48/264 (18%), Positives = 119/264 (45%), Gaps = 41/264 (15%)
Query: 412 EIQHLL--QQPPDLQ-------------PENTEPQNQQILQMSYQDIRSEVMEETKEWKS 456
++QHLL QQ D + PE + + ++ + +D +S+ ++ +
Sbjct: 1266 DLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREER 1325
Query: 457 EEELHRRKSSRRHSLNQQT---KALQYLRRHSLD-----VQAKGQKSSKRHSLDQQSKGW 508
EE+ R+++ R+ +Q + Q LRR D + + Q+ ++ ++Q
Sbjct: 1326 EEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRR 1385
Query: 509 QSPKQKSL--DQQIKDWLSPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKD 566
Q ++K L +QQ++ ++ D+ + + ++QL Q+ + + + EQ Q ++
Sbjct: 1386 QERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERE 1445
Query: 567 GQV--KDQQTDKEQNSK-------------KQTQDQQTEDQPAQEKKSPKGQFQNVQAEG 611
+ ++QQ +E++ K +Q Q+ + + +E++ + Q ++ +
Sbjct: 1446 RKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFRE 1505
Query: 612 QQAQVEKVPKLLCQDSESQIQQYQ 635
Q+ + ++ P+ + E Q+ + Q
Sbjct: 1506 QELRSQE-PERKFLEEEQQLHRQQ 1528
Score = 32.0 bits (71), Expect = 1.9
Identities = 32/147 (21%), Positives = 73/147 (49%), Gaps = 10/147 (6%)
Query: 489 QAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQLPDQQ 548
QA G KR D + Q +Q+ ++ + P+ ++++ + +++ Q+
Sbjct: 91 QATGLDEEKRARCDGKESLLQDRRQEEDQRRFE----PRDRQLEEEPGQRRRQKR---QE 143
Query: 549 AEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEK--KSPKGQFQN 606
E + A+GE+ E Q + Q +D+Q E+ +++ + Q+ E++ A+E+ +S KG
Sbjct: 144 QERELAEGEEQSEKQERLEQ-RDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETE 202
Query: 607 VQAEGQQAQVEKVPKLLCQDSESQIQQ 633
+ +Q + ++ +L + E + QQ
Sbjct: 203 EFPDEEQLRRRELLELRRKGREEKQQQ 229
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 55.8 bits (133), Expect = 1e-07
Identities = 89/414 (21%), Positives = 170/414 (41%), Gaps = 61/414 (14%)
Query: 235 PPTLEKKPSENMSIQLDST-FKQMKDEDLQSAIVQPSQMQTKLLQDQAASLQVFPSHSAL 293
PP + + E ++ Q + T QM+ Q ++Q Q Q +AA AL
Sbjct: 593 PPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLAL 652
Query: 294 KLEDISPEDLPSQALPVEGLSEQTMPSKSTSSHVKQSSNLTANDLPPQGILSQDTSSQDM 353
L+ Q L + + +PS + S V + ++ Q T+SQ
Sbjct: 653 LLQQF-------QTLKMRISDQNIIPSVTRSVSVPDTGSIWE---------LQPTASQPT 696
Query: 354 LFHDMTSQDMQSLDMLSQDTPSHAMPPQDIPSQDMLSQALSAHAILPEASTSHIVQFPEI 413
++ + D+ L TP P+ + L Q A A E
Sbjct: 697 VWEGGSVWDLP----LDTTTPG--------PALEQLQQLEKAKAAKLE------------ 732
Query: 414 QHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQ 473
Q + + E E + Q+ L+ ++I EE ++ + EEEL RRK + +L +
Sbjct: 733 QERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRK--QEEALRR 790
Query: 474 QTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSL----DQQIKDWLSPKRH 529
Q + LRR + + + Q+ + R +++ + + KQ+ L +++ W R
Sbjct: 791 QREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKW---ARE 847
Query: 530 SVDKQAQLNQTKEQLPDQQA----EDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQ 585
+ Q +L + + ++ ++ A E+++ K ++ + K+ +Q ++Q + ++ Q
Sbjct: 848 EEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELM---RQRQQQQEALRRLQ 904
Query: 586 DQQTEDQPAQEK---KSPKGQFQNVQAEGQQAQVEKVP-KLLCQDSESQIQQYQ 635
QQ + Q AQ K S GQ N A QA + + L ++ E Q+++ Q
Sbjct: 905 QQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ 958
Score = 42.4 bits (98), Expect = 0.001
Identities = 43/181 (23%), Positives = 73/181 (40%), Gaps = 12/181 (6%)
Query: 431 QNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKS---SRRHSL----NQQTKALQYLRR 483
+ ++ Q ++ R + EE + EEE +RK R+ L QQ +AL+ L++
Sbjct: 846 REEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQ 905
Query: 484 HSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQ 543
Q K + QQS Q +L L +R ++ Q Q +E
Sbjct: 906 QQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQREL 965
Query: 544 LP--DQQAEDQQAKGEQYPEGQSKDGQVK---DQQTDKEQNSKKQTQDQQTEDQPAQEKK 598
+ QQ + QQ K + G K + Q ++ + +KQ Q QQ QP + +
Sbjct: 966 MKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARN 1025
Query: 599 S 599
+
Sbjct: 1026 N 1026
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 55.8 bits (133), Expect = 1e-07
Identities = 89/414 (21%), Positives = 170/414 (41%), Gaps = 61/414 (14%)
Query: 235 PPTLEKKPSENMSIQLDST-FKQMKDEDLQSAIVQPSQMQTKLLQDQAASLQVFPSHSAL 293
PP + + E ++ Q + T QM+ Q ++Q Q Q +AA AL
Sbjct: 620 PPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLAL 679
Query: 294 KLEDISPEDLPSQALPVEGLSEQTMPSKSTSSHVKQSSNLTANDLPPQGILSQDTSSQDM 353
L+ Q L + + +PS + S V + ++ Q T+SQ
Sbjct: 680 LLQQF-------QTLKMRISDQNIIPSVTRSVSVPDTGSIWE---------LQPTASQPT 723
Query: 354 LFHDMTSQDMQSLDMLSQDTPSHAMPPQDIPSQDMLSQALSAHAILPEASTSHIVQFPEI 413
++ + D+ L TP P+ + L Q A A E
Sbjct: 724 VWEGGSVWDLP----LDTTTPG--------PALEQLQQLEKAKAAKLE------------ 759
Query: 414 QHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQ 473
Q + + E E + Q+ L+ ++I EE ++ + EEEL RRK + +L +
Sbjct: 760 QERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRK--QEEALRR 817
Query: 474 QTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSL----DQQIKDWLSPKRH 529
Q + LRR + + + Q+ + R +++ + + KQ+ L +++ W R
Sbjct: 818 QREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKW---ARE 874
Query: 530 SVDKQAQLNQTKEQLPDQQA----EDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQ 585
+ Q +L + + ++ ++ A E+++ K ++ + K+ +Q ++Q + ++ Q
Sbjct: 875 EEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELM---RQRQQQQEALRRLQ 931
Query: 586 DQQTEDQPAQEK---KSPKGQFQNVQAEGQQAQVEKVP-KLLCQDSESQIQQYQ 635
QQ + Q AQ K S GQ N A QA + + L ++ E Q+++ Q
Sbjct: 932 QQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ 985
Score = 42.4 bits (98), Expect = 0.001
Identities = 43/181 (23%), Positives = 73/181 (40%), Gaps = 12/181 (6%)
Query: 431 QNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKS---SRRHSL----NQQTKALQYLRR 483
+ ++ Q ++ R + EE + EEE +RK R+ L QQ +AL+ L++
Sbjct: 873 REEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQ 932
Query: 484 HSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQ 543
Q K + QQS Q +L L +R ++ Q Q +E
Sbjct: 933 QQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQREL 992
Query: 544 LP--DQQAEDQQAKGEQYPEGQSKDGQVK---DQQTDKEQNSKKQTQDQQTEDQPAQEKK 598
+ QQ + QQ K + G K + Q ++ + +KQ Q QQ QP + +
Sbjct: 993 MKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARN 1052
Query: 599 S 599
+
Sbjct: 1053 N 1053
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 55.8 bits (133), Expect = 1e-07
Identities = 89/414 (21%), Positives = 170/414 (41%), Gaps = 61/414 (14%)
Query: 235 PPTLEKKPSENMSIQLDST-FKQMKDEDLQSAIVQPSQMQTKLLQDQAASLQVFPSHSAL 293
PP + + E ++ Q + T QM+ Q ++Q Q Q +AA AL
Sbjct: 599 PPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLAL 658
Query: 294 KLEDISPEDLPSQALPVEGLSEQTMPSKSTSSHVKQSSNLTANDLPPQGILSQDTSSQDM 353
L+ Q L + + +PS + S V + ++ Q T+SQ
Sbjct: 659 LLQQF-------QTLKMRISDQNIIPSVTRSVSVPDTGSIWE---------LQPTASQPT 702
Query: 354 LFHDMTSQDMQSLDMLSQDTPSHAMPPQDIPSQDMLSQALSAHAILPEASTSHIVQFPEI 413
++ + D+ L TP P+ + L Q A A E
Sbjct: 703 VWEGGSVWDLP----LDTTTPG--------PALEQLQQLEKAKAAKLE------------ 738
Query: 414 QHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQ 473
Q + + E E + Q+ L+ ++I EE ++ + EEEL RRK + +L +
Sbjct: 739 QERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRK--QEEALRR 796
Query: 474 QTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSL----DQQIKDWLSPKRH 529
Q + LRR + + + Q+ + R +++ + + KQ+ L +++ W R
Sbjct: 797 QREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKW---ARE 853
Query: 530 SVDKQAQLNQTKEQLPDQQA----EDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQ 585
+ Q +L + + ++ ++ A E+++ K ++ + K+ +Q ++Q + ++ Q
Sbjct: 854 EEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELM---RQRQQQQEALRRLQ 910
Query: 586 DQQTEDQPAQEK---KSPKGQFQNVQAEGQQAQVEKVP-KLLCQDSESQIQQYQ 635
QQ + Q AQ K S GQ N A QA + + L ++ E Q+++ Q
Sbjct: 911 QQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ 964
Score = 42.4 bits (98), Expect = 0.001
Identities = 43/181 (23%), Positives = 73/181 (40%), Gaps = 12/181 (6%)
Query: 431 QNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKS---SRRHSL----NQQTKALQYLRR 483
+ ++ Q ++ R + EE + EEE +RK R+ L QQ +AL+ L++
Sbjct: 852 REEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQ 911
Query: 484 HSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQ 543
Q K + QQS Q +L L +R ++ Q Q +E
Sbjct: 912 QQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQREL 971
Query: 544 LP--DQQAEDQQAKGEQYPEGQSKDGQVK---DQQTDKEQNSKKQTQDQQTEDQPAQEKK 598
+ QQ + QQ K + G K + Q ++ + +KQ Q QQ QP + +
Sbjct: 972 MKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARN 1031
Query: 599 S 599
+
Sbjct: 1032 N 1032
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 55.8 bits (133), Expect = 1e-07
Identities = 89/414 (21%), Positives = 170/414 (41%), Gaps = 61/414 (14%)
Query: 235 PPTLEKKPSENMSIQLDST-FKQMKDEDLQSAIVQPSQMQTKLLQDQAASLQVFPSHSAL 293
PP + + E ++ Q + T QM+ Q ++Q Q Q +AA AL
Sbjct: 599 PPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLAL 658
Query: 294 KLEDISPEDLPSQALPVEGLSEQTMPSKSTSSHVKQSSNLTANDLPPQGILSQDTSSQDM 353
L+ Q L + + +PS + S V + ++ Q T+SQ
Sbjct: 659 LLQQF-------QTLKMRISDQNIIPSVTRSVSVPDTGSIWE---------LQPTASQPT 702
Query: 354 LFHDMTSQDMQSLDMLSQDTPSHAMPPQDIPSQDMLSQALSAHAILPEASTSHIVQFPEI 413
++ + D+ L TP P+ + L Q A A E
Sbjct: 703 VWEGGSVWDLP----LDTTTPG--------PALEQLQQLEKAKAAKLE------------ 738
Query: 414 QHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQ 473
Q + + E E + Q+ L+ ++I EE ++ + EEEL RRK + +L +
Sbjct: 739 QERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRK--QEEALRR 796
Query: 474 QTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSL----DQQIKDWLSPKRH 529
Q + LRR + + + Q+ + R +++ + + KQ+ L +++ W R
Sbjct: 797 QREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKW---ARE 853
Query: 530 SVDKQAQLNQTKEQLPDQQA----EDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQ 585
+ Q +L + + ++ ++ A E+++ K ++ + K+ +Q ++Q + ++ Q
Sbjct: 854 EEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELM---RQRQQQQEALRRLQ 910
Query: 586 DQQTEDQPAQEK---KSPKGQFQNVQAEGQQAQVEKVP-KLLCQDSESQIQQYQ 635
QQ + Q AQ K S GQ N A QA + + L ++ E Q+++ Q
Sbjct: 911 QQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ 964
Score = 42.4 bits (98), Expect = 0.001
Identities = 43/181 (23%), Positives = 73/181 (40%), Gaps = 12/181 (6%)
Query: 431 QNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKS---SRRHSL----NQQTKALQYLRR 483
+ ++ Q ++ R + EE + EEE +RK R+ L QQ +AL+ L++
Sbjct: 852 REEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQ 911
Query: 484 HSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQ 543
Q K + QQS Q +L L +R ++ Q Q +E
Sbjct: 912 QQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQREL 971
Query: 544 LP--DQQAEDQQAKGEQYPEGQSKDGQVK---DQQTDKEQNSKKQTQDQQTEDQPAQEKK 598
+ QQ + QQ K + G K + Q ++ + +KQ Q QQ QP + +
Sbjct: 972 MKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARN 1031
Query: 599 S 599
+
Sbjct: 1032 N 1032
>gi|214831008 membrane-spanning 4-domains, subfamily A, member 2
isoform 2 [Homo sapiens]
Length = 195
Score = 54.3 bits (129), Expect = 4e-07
Identities = 47/162 (29%), Positives = 65/162 (40%), Gaps = 38/162 (23%)
Query: 10 ATHVITIKPNET----VLTAFPYRPHSSLLDFLKGEPRVLGATQILLALIIVGFGTIF-- 63
A V+ I P E +L + P + L LK E LG TQIL A+I + FGT+
Sbjct: 22 AFEVLEISPQEVSSGRLLKSASSPPLHTWLTVLKKEQEFLGVTQILTAMICLCFGTVVCS 81
Query: 64 ALNYIGFSQRLPLVVLTGYPFWGAL-------------------IGQGVTGMNVISSLVA 104
L+ + GYPFWGA+ + +G G N SS+
Sbjct: 82 VLDISHIEGDIFSSFKAGYPFWGAIFFSISGMLSIISERRNATYLVRGSLGANTASSIAG 141
Query: 105 ITGITFTILSYRHQDKY-------------CQMPSFEEICVF 133
TGIT I++ + Y C M SF +C+F
Sbjct: 142 GTGITILIINLKKSLAYIHIHSCQKFFETKCFMASFSTVCIF 183
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 54.3 bits (129), Expect = 4e-07
Identities = 44/253 (17%), Positives = 111/253 (43%), Gaps = 25/253 (9%)
Query: 411 PEIQ-HLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVM----------EETKEWKSEEE 459
P++Q + LQ+ Q E Q ++I + + R E +E K W+ E+
Sbjct: 263 PQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKR 322
Query: 460 LHRRKSSRRHS---------LNQQTKALQYLRRHSLDVQAKGQKSSKR-----HSLDQQS 505
L ++ R L +Q + +Q + + K ++ ++ L +Q
Sbjct: 323 LREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE 382
Query: 506 KGWQSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSK 565
K + +QK DQ+ + W +R ++ Q K ++ +++ EQ + + +
Sbjct: 383 KQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQ 442
Query: 566 DGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQ 625
+ ++++++ +E+ K + +++ +Q + +K + ++ + E QQ ++ + + L +
Sbjct: 443 EEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWE 502
Query: 626 DSESQIQQYQFWQ 638
+ Q Q+ + W+
Sbjct: 503 QEKMQEQEEKIWE 515
Score = 49.3 bits (116), Expect = 1e-05
Identities = 48/234 (20%), Positives = 106/234 (45%), Gaps = 23/234 (9%)
Query: 424 QPENTEPQNQQILQMSYQDIRSEVMEETKE--WKSEEELHRRKSSRRHSLNQQTKALQYL 481
+ E E Q Q++ + + E M+E +E W+ EE++ + Q+ K +
Sbjct: 482 EQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIR----DQEEMWGQEKKMWRQE 537
Query: 482 RRHSLDVQAKGQKSSKRHSLDQQSKGW---QSPKQKSLDQQIKDWLSPKRHSVDKQAQLN 538
+ + Q Q+ R DQ+ K W + ++K+ +Q+ K W ++ +++ +
Sbjct: 538 KMREQEDQMWEQEEKMR---DQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMRER 594
Query: 539 QTK----EQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQ------TQDQQ 588
+ K E++ +Q E Q + E+ E + K + +++ ++E+ +Q +++
Sbjct: 595 EKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKM 654
Query: 589 TEDQPAQEKKSPKGQFQNVQ-AEGQQAQVEKVPKLLCQDSESQIQQYQFWQFHK 641
E Q E+K + + +Q E Q Q EK+ + + ++Q Q+ + W K
Sbjct: 655 WEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEK 708
Score = 45.8 bits (107), Expect = 1e-04
Identities = 36/217 (16%), Positives = 98/217 (45%), Gaps = 26/217 (11%)
Query: 441 QDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHS 500
Q+ + ++ ++ + EE + R+ R + + +++ ++ + +K ++
Sbjct: 433 QEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQR 492
Query: 501 L-DQQSKGWQSPKQKSLDQQI------------------KDWLSPKRHSVDKQAQLNQTK 541
L +Q+ K W+ K + +++I K W K + Q + K
Sbjct: 493 LPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEK 552
Query: 542 EQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPK 601
+ +Q+ DQ+ + E+ + Q K + D+E+ +++ + ++ E + +E++ +
Sbjct: 553 MRDQEQKMWDQEERMEKKTQEQEK------KTWDQEEKMREEERMREREKKMREEEEMMR 606
Query: 602 GQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQ 638
Q + +Q + ++ Q E+ K+ Q+ + Q Q+ + W+
Sbjct: 607 EQEEKMQEQEEKMQ-EQEEKMWEQEEKMQEQEEKMWE 642
Score = 43.5 bits (101), Expect = 6e-04
Identities = 39/239 (16%), Positives = 103/239 (43%), Gaps = 19/239 (7%)
Query: 414 QHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQ 473
Q + Q ++ + E + + Q + E K+ + EEE+ R + + + +
Sbjct: 558 QKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEK---MQE 614
Query: 474 QTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPK-----QKSLDQQIKDWLSPKR 528
Q + +Q + + K Q+ ++ +Q+ K W+ + Q+ +Q+ K W K
Sbjct: 615 QEEKMQEQEEKMWEQEEKMQEQEEK-MWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKM 673
Query: 529 HSVDKQAQLNQT---------KEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQN 579
+K + + K Q +++ DQ+ E+ + + ++++ +EQ
Sbjct: 674 QEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQE 733
Query: 580 SKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQ 638
K Q Q+++ ++Q + + + ++ + +Q ++ + + L + + Q +Q + W+
Sbjct: 734 EKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQ-EQEKIWE 791
Score = 43.1 bits (100), Expect = 8e-04
Identities = 48/234 (20%), Positives = 108/234 (46%), Gaps = 28/234 (11%)
Query: 412 EIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEEL--HRRKSSRRH 469
E + +Q+ + E E +Q +M Q+ + EE K W+ EE++ +R ++
Sbjct: 607 EQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEE-KMWEQEEKMWEQQRLPEQKE 665
Query: 470 SLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPK---QKSLDQQIKDWLSP 526
L + K + + + + Q+ ++ + +Q+ K W K ++S+ ++ K
Sbjct: 666 KLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREE 725
Query: 527 KRHSVDKQAQLNQTKEQLPDQQAE---------DQQAK---GEQYPEGQSK---DGQVKD 571
+ +++ ++ + +E++ +Q+ E +Q+ K ++ PE + K ++++
Sbjct: 726 EEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQE 785
Query: 572 QQTDKEQNSKKQTQDQ----QTEDQPAQEKKSPKGQFQNV--QAEGQQAQVEKV 619
Q+ EQ K + Q++ Q E QE+K +GQ + + Q E Q EK+
Sbjct: 786 QEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKM-RGQEEKMWGQEEKMWGQEEKM 838
Score = 42.7 bits (99), Expect = 0.001
Identities = 39/211 (18%), Positives = 91/211 (43%), Gaps = 5/211 (2%)
Query: 412 EIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSL 471
E + +Q+ + E E +Q +M Q+ R + E+ K+ + +E+ R + R
Sbjct: 345 EQEEQMQEQEEKMWEQEEKMREQEEKMWRQEER--LWEQEKQMREQEQKMRDQEERMWEQ 402
Query: 472 NQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSV 531
+++ + + R + + +K + + +Q K + ++K +++ K
Sbjct: 403 DERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREE 462
Query: 532 DKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTED 591
++ + + K Q ++ +Q+ K Q + ++ +Q+ +EQ K Q+++ D
Sbjct: 463 EETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRD 522
Query: 592 QP---AQEKKSPKGQFQNVQAEGQQAQVEKV 619
Q QEKK + + Q + Q EK+
Sbjct: 523 QEEMWGQEKKMWRQEKMREQEDQMWEQEEKM 553
Score = 40.4 bits (93), Expect = 0.005
Identities = 38/219 (17%), Positives = 94/219 (42%), Gaps = 13/219 (5%)
Query: 414 QHLLQQPPDLQPENTEPQNQQILQMSYQDIR-----SEVMEETKEWKSEEELHRRKSSRR 468
+ L +Q ++ + + ++Q+ +M QD R + E+ K W+ E++ K +
Sbjct: 376 ERLWEQEKQMREQEQKMRDQEE-RMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQE 434
Query: 469 HSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKR 528
+ + + + + K + + +Q+ K Q ++ +Q+ K+W +R
Sbjct: 435 QEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEK-MQKQEENMWEQEEKEW-QQQR 492
Query: 529 HSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQ 588
K+ Q K Q +++ +Q+ K E ++ ++ Q+ +EQ + Q+++
Sbjct: 493 LPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEK 552
Query: 589 TEDQ-----PAQEKKSPKGQFQNVQAEGQQAQVEKVPKL 622
DQ +E+ K Q Q + Q+ ++ + ++
Sbjct: 553 MRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERM 591
Score = 40.0 bits (92), Expect = 0.007
Identities = 50/226 (22%), Positives = 104/226 (46%), Gaps = 19/226 (8%)
Query: 412 EIQHLLQQPPDLQPENTEPQNQQILQMSYQDI-RSEVMEETKEWKSEEELHRRKSSRRHS 470
E Q L +Q L E+ + Q Q+ +Q + I E ME+ + + ++ + K S
Sbjct: 656 EQQRLPEQKEKLW-EHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEES 714
Query: 471 LNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHS 530
+ ++ K ++ + + K Q+ ++ +Q+ + W+ ++K +Q+ K W
Sbjct: 715 MREREKKMREEEEMMREQEEKMQEQEEKMQ-EQEEEMWEQ-EEKMWEQEEKMW------- 765
Query: 531 VDKQAQLNQTKEQLPDQQAEDQQAK-GEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQT 589
+Q +L + KE+L + + +Q K EQ E + +D + K + +++ +++ Q
Sbjct: 766 --EQQRLPEQKEKLWEHEKMQEQEKIWEQ--EEKMRDQEEKMRGQEEKMRGQEEKMRGQE 821
Query: 590 EDQPAQEKKSPKGQFQNV--QAEGQQAQVEKVPKLLCQDSESQIQQ 633
E QE+K GQ + + Q E Q EK+ + + E +Q
Sbjct: 822 EKMWGQEEKM-WGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQ 866
Score = 39.7 bits (91), Expect = 0.009
Identities = 42/237 (17%), Positives = 104/237 (43%), Gaps = 30/237 (12%)
Query: 409 QFPEIQHLLQQPPDLQP-ENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSR 467
+ PE + L + +Q E + Q ++I + + +++ E+ K W E+
Sbjct: 659 RLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEK-KTWDQEKMREEESMRE 717
Query: 468 RHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPK-----QKSLDQQIKD 522
R ++ + + + + Q + + + +Q+ K W+ + Q+ +Q+ K
Sbjct: 718 REKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKL 777
Query: 523 WLSPKRHSVDKQAQLNQTKEQLPDQQ----AEDQQAKG-EQYPEGQSKD---------GQ 568
W + + +Q ++ + +E++ DQ+ ++++ +G E+ GQ + GQ
Sbjct: 778 W---EHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQ 834
Query: 569 VKDQQTDKE----QNSKKQTQDQQTEDQPAQEKKSPKGQFQNV--QAEGQQAQVEKV 619
+ +E Q K + + Q E++ ++++ +GQ + + Q E + Q EK+
Sbjct: 835 EEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKI 891
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 54.3 bits (129), Expect = 4e-07
Identities = 47/234 (20%), Positives = 112/234 (47%), Gaps = 11/234 (4%)
Query: 408 VQFPEIQHLL-QQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSS 466
V+ E+ +LL QQ + E +Q +M Q+++ EE K W+ EE++H ++
Sbjct: 282 VEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEE-KMWRQEEKMHEQEEK 340
Query: 467 RRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSP 526
R ++ + + +R ++ + +K + +Q + + +K +Q+ + W
Sbjct: 341 IREQEDKMWRQEEKIREQEEKIREQEEK------MWRQEEKIREQDEKIQEQEEEMWRQE 394
Query: 527 K--RHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQT 584
+ R +K+ + +E+ +Q E + + E+ + K ++++ D+E+ ++
Sbjct: 395 EKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVE 454
Query: 585 QDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQ 638
+ Q E++ QE++ K Q Q + + Q+ + + KLL Q+ + Q+ + W+
Sbjct: 455 EKMQEEEEKMQEQEE-KIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWR 507
Score = 45.4 bits (106), Expect = 2e-04
Identities = 38/204 (18%), Positives = 95/204 (46%), Gaps = 19/204 (9%)
Query: 449 EETKEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDVQA------KGQKSSKRHSLD 502
+E K W+ EE++ ++ R + + + +R +Q + ++ +
Sbjct: 344 QEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEK 403
Query: 503 QQSKGW-QSPKQKSLDQQIKD-----WLSPKR-HSVDKQAQLNQTK-EQLPDQQAEDQQA 554
+Q K W Q K + D++I++ W ++ +++ Q + K ++ ++ E+++
Sbjct: 404 RQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEK 463
Query: 555 KGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQA 614
EQ + Q ++ ++++Q+ + K Q+++ +Q +EK + + Q E Q
Sbjct: 464 MQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQ--EEKMWRQEEKMWEQEEKMQE 521
Query: 615 QVEKVPKLLCQDSESQIQQYQFWQ 638
Q EK+ + Q+ + + Q+ + WQ
Sbjct: 522 QEEKMQR---QEEKMREQEVRLWQ 542
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 54.3 bits (129), Expect = 4e-07
Identities = 47/234 (20%), Positives = 112/234 (47%), Gaps = 11/234 (4%)
Query: 408 VQFPEIQHLL-QQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSS 466
V+ E+ +LL QQ + E +Q +M Q+++ EE K W+ EE++H ++
Sbjct: 282 VEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEE-KMWRQEEKMHEQEEK 340
Query: 467 RRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSP 526
R ++ + + +R ++ + +K + +Q + + +K +Q+ + W
Sbjct: 341 IREQEDKMWRQEEKIREQEEKIREQEEK------MWRQEEKIREQDEKIQEQEEEMWRQE 394
Query: 527 K--RHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQT 584
+ R +K+ + +E+ +Q E + + E+ + K ++++ D+E+ ++
Sbjct: 395 EKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVE 454
Query: 585 QDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQ 638
+ Q E++ QE++ K Q Q + + Q+ + + KLL Q+ + Q+ + W+
Sbjct: 455 EKMQEEEEKMQEQEE-KIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWR 507
Score = 45.4 bits (106), Expect = 2e-04
Identities = 38/204 (18%), Positives = 95/204 (46%), Gaps = 19/204 (9%)
Query: 449 EETKEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDVQA------KGQKSSKRHSLD 502
+E K W+ EE++ ++ R + + + +R +Q + ++ +
Sbjct: 344 QEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEK 403
Query: 503 QQSKGW-QSPKQKSLDQQIKD-----WLSPKR-HSVDKQAQLNQTK-EQLPDQQAEDQQA 554
+Q K W Q K + D++I++ W ++ +++ Q + K ++ ++ E+++
Sbjct: 404 RQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEK 463
Query: 555 KGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQA 614
EQ + Q ++ ++++Q+ + K Q+++ +Q +EK + + Q E Q
Sbjct: 464 MQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQ--EEKMWRQEEKMWEQEEKMQE 521
Query: 615 QVEKVPKLLCQDSESQIQQYQFWQ 638
Q EK+ + Q+ + + Q+ + WQ
Sbjct: 522 QEEKMQR---QEEKMREQEVRLWQ 542
>gi|20070328 membrane-spanning 4-domains, subfamily A, member 4
isoform a [Homo sapiens]
Length = 220
Score = 53.5 bits (127), Expect = 6e-07
Identities = 35/108 (32%), Positives = 49/108 (45%), Gaps = 22/108 (20%)
Query: 37 FLKGEPRVLGATQILLALIIVGFGTIFALNYIGFSQRLPLVVLTGYPFWGAL-------- 88
FLKGEP+VLG QIL AL+ + G P+ V GY WG++
Sbjct: 39 FLKGEPKVLGVVQILTALMSLSMGITMMCMASNTYGSNPISVYIGYTIWGSVMFIISGSL 98
Query: 89 -----------IGQGVTGMNVISSLVAITGI---TFTILSYRHQDKYC 122
+ +G GMN+ SS++A +GI TF++ Y YC
Sbjct: 99 SIAAGIRTTKGLVRGSLGMNITSSVLAASGILINTFSLAFYSFHHPYC 146
>gi|23110995 membrane-spanning 4-domains, subfamily A, member 4
isoform b [Homo sapiens]
Length = 239
Score = 53.5 bits (127), Expect = 6e-07
Identities = 35/108 (32%), Positives = 49/108 (45%), Gaps = 22/108 (20%)
Query: 37 FLKGEPRVLGATQILLALIIVGFGTIFALNYIGFSQRLPLVVLTGYPFWGAL-------- 88
FLKGEP+VLG QIL AL+ + G P+ V GY WG++
Sbjct: 58 FLKGEPKVLGVVQILTALMSLSMGITMMCMASNTYGSNPISVYIGYTIWGSVMFIISGSL 117
Query: 89 -----------IGQGVTGMNVISSLVAITGI---TFTILSYRHQDKYC 122
+ +G GMN+ SS++A +GI TF++ Y YC
Sbjct: 118 SIAAGIRTTKGLVRGSLGMNITSSVLAASGILINTFSLAFYSFHHPYC 165
>gi|4503677 membrane-spanning 4-domains, subfamily A, member 2
isoform 1 [Homo sapiens]
Length = 244
Score = 53.1 bits (126), Expect = 8e-07
Identities = 49/167 (29%), Positives = 70/167 (41%), Gaps = 32/167 (19%)
Query: 10 ATHVITIKPNET----VLTAFPYRPHSSLLDFLKGEPRVLGATQILLALIIVGFGTIF-- 63
A V+ I P E +L + P + L LK E LG TQIL A+I + FGT+
Sbjct: 22 AFEVLEISPQEVSSGRLLKSASSPPLHTWLTVLKKEQEFLGVTQILTAMICLCFGTVVCS 81
Query: 64 ALNYIGFSQRLPLVVLTGYPFWGAL-------------------IGQGVTGMNVISSLVA 104
L+ + GYPFWGA+ + +G G N SS+
Sbjct: 82 VLDISHIEGDIFSSFKAGYPFWGAIFFSISGMLSIISERRNATYLVRGSLGANTASSIAG 141
Query: 105 ITGITFTILSYRHQDKYCQMPS----FEEICV---FSRTLFIVLFFL 144
TGIT I++ + Y + S FE C FS + +++ FL
Sbjct: 142 GTGITILIINLKKSLAYIHIHSCQKFFETKCFMASFSTEIVVMMLFL 188
>gi|23110997 membrane-spanning 4-domains, subfamily A, member 5
[Homo sapiens]
Length = 200
Score = 53.1 bits (126), Expect = 8e-07
Identities = 45/155 (29%), Positives = 65/155 (41%), Gaps = 31/155 (20%)
Query: 21 TVLTAFPYRPHSSLLDFLKGEPRVLGATQILLALIIVGFGTIFALNYIGFSQRLPLVVLT 80
T L+A + S L + ++LG QIL ++ FG IF + R P + L+
Sbjct: 26 TELSATTFSTQSPLQKLFARKMKILGTIQILFGIMTFSFGVIFLFTLLKPYPRFPFIFLS 85
Query: 81 GYPFWGAL--IGQGV-----------------TGMNVISSLVAITGI---TF-------T 111
GYPFWG++ I G MN +S+L AI GI TF
Sbjct: 86 GYPFWGSVLFINSGAFLIAVKRKTTETLIILSRIMNFLSALGAIAGIILLTFGFILDQNY 145
Query: 112 ILSYRHQDKYCQMPS--FEEICVFSRTLFIVLFFL 144
I Y HQ+ C+ + F I + T I+ F+
Sbjct: 146 ICGYSHQNSQCKAVTVLFLGILITLMTFSIIELFI 180
>gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 4 isoform 1 [Homo
sapiens]
Length = 1834
Score = 52.8 bits (125), Expect = 1e-06
Identities = 44/238 (18%), Positives = 111/238 (46%), Gaps = 14/238 (5%)
Query: 393 LSAHAILPEASTSHIVQFPEIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETK 452
L+A + PE ++ +Q P+ + + P QP E ++ Q + +S +++ S
Sbjct: 1456 LTAQQMKPEKPST--LQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPD 1513
Query: 453 EWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQ-SKGWQSP 511
WK + + K + H ++ +K +Q L+ D A+ ++ L+ Q K Q
Sbjct: 1514 PWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKP-DRSAEESDRLRKLMLEWQFQKRLQES 1572
Query: 512 KQKSLDQQ------IKDWLSPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSK 565
KQK D + + L +R +++A+ + D ++++ + +Q E + +
Sbjct: 1573 KQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKR 1632
Query: 566 DGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLL 623
+ + + +Q + +++ ++++T+ ++++ +G + ++AE ++ E +LL
Sbjct: 1633 EAEDRARQ----EEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLL 1686
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 52.4 bits (124), Expect = 1e-06
Identities = 35/210 (16%), Positives = 97/210 (46%), Gaps = 9/210 (4%)
Query: 409 QFPEIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRR 468
Q E + +Q+ + E E +Q QM Q+ + + EE + K EE++ +++ R
Sbjct: 207 QMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQ-KQEEQMRKQEEQMR 265
Query: 469 HSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKR 528
Q + + + + + + Q + + +Q + + +++ +Q+
Sbjct: 266 EQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQE--------E 317
Query: 529 HSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQ 588
+++ Q+ + +EQ+ +Q+ + + K + + + + Q + Q +EQ K++ Q ++
Sbjct: 318 QMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRK 377
Query: 589 TEDQPAQEKKSPKGQFQNVQAEGQQAQVEK 618
E+Q ++++ + Q + + + +Q +K
Sbjct: 378 QEEQMRKQEEQMRKQEEQMGEQKEQMGEQK 407
Score = 50.1 bits (118), Expect = 7e-06
Identities = 37/192 (19%), Positives = 87/192 (45%), Gaps = 7/192 (3%)
Query: 409 QFPEIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRR 468
Q + + +++ + E E +Q QM Q ++E E+T E EE++ ++ R
Sbjct: 249 QVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGE--QEEQMREQEEQMR 306
Query: 469 HSLNQQTKALQYLRRHS--LDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSP 526
Q + + +R + Q + K +Q+ + W+ +Q + ++ +
Sbjct: 307 EQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMG---EQEEQMQK 363
Query: 527 KRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQD 586
+ V KQ + + +E+ +Q E + + EQ E + + G+ K+Q ++E+ +Q +
Sbjct: 364 QEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQ 423
Query: 587 QQTEDQPAQEKK 598
+ +++ E+K
Sbjct: 424 MRKQEEHMGEQK 435
Score = 49.7 bits (117), Expect = 9e-06
Identities = 43/225 (19%), Positives = 102/225 (45%), Gaps = 13/225 (5%)
Query: 426 ENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHS 485
E +Q QM Q+ + EE + K EE++ ++ R Q + + +++
Sbjct: 189 EQEGQMGEQEGQMGEQEEQMGEQEEQMQ-KQEEQMGEQEEQMRKQEEQMGEQEEQVQKQE 247
Query: 486 LDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQLP 545
VQ + ++ K+ ++Q + + ++ +Q +K ++ +++ Q + +EQ+
Sbjct: 248 EQVQKQEEQMRKQ---EEQMREQEEQMREQEEQMLK-----QKEQTEQEEQTGEQEEQMR 299
Query: 546 DQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQ 605
+Q E+Q + E+ Q + + +++Q K++ + ++Q E + K+ + Q
Sbjct: 300 EQ--EEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQ 357
Query: 606 NVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQFHKGNLQAGQPR 650
Q + Q+ QV K + + + E +Q + Q K Q G+ +
Sbjct: 358 EEQMQKQEEQVRKQEEQMRKQEEQMRKQEE--QMRKQEEQMGEQK 400
Score = 44.7 bits (104), Expect = 3e-04
Identities = 27/156 (17%), Positives = 79/156 (50%), Gaps = 8/156 (5%)
Query: 489 QAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQLPDQ- 547
+ +GQ + + +Q +G +++ + +Q + + +++ Q+ + +EQ+ +Q
Sbjct: 182 EQEGQVREQEGQMGEQ-EGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQE 240
Query: 548 -----QAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKG 602
Q E Q + EQ + + + + ++Q ++E+ KQ + + E+Q ++++ +
Sbjct: 241 EQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMRE 300
Query: 603 QFQNVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQ 638
Q + ++ + +Q + E+ ++ Q+ + Q+ Q W+
Sbjct: 301 QEEQMREQEEQMR-EQEEQMREQEEQMGKQEEQMWE 335
Score = 40.0 bits (92), Expect = 0.007
Identities = 31/189 (16%), Positives = 85/189 (44%), Gaps = 4/189 (2%)
Query: 449 EETKEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGW 508
+E + + E ++ ++ R Q + +R V+ + + ++ ++ +G
Sbjct: 127 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 186
Query: 509 QSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQLPDQQAE---DQQAKGEQYPEGQSK 565
++ + +Q + +++ Q+ + +EQ+ +Q+ + ++ GEQ + Q +
Sbjct: 187 VREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQ 246
Query: 566 DGQVKDQQTD-KEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLC 624
+ QV+ Q+ ++Q + + Q++Q +Q Q K + Q Q Q+ Q+ + + +
Sbjct: 247 EEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMR 306
Query: 625 QDSESQIQQ 633
+ E +Q
Sbjct: 307 EQEEQMREQ 315
Score = 38.1 bits (87), Expect = 0.026
Identities = 48/233 (20%), Positives = 109/233 (46%), Gaps = 22/233 (9%)
Query: 422 DLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQQTKALQYL 481
+L+ +N E Q + LQ+ + +SE+ KE K + E + + + +Q ++
Sbjct: 8 ELKEKNAELQEE--LQLVETE-KSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVR-- 62
Query: 482 RRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTK 541
+ Q + Q+ R Q + Q + + + Q+++ R +++ Q+ + +
Sbjct: 63 ---EQEGQVREQEGQVREQEGQVRE--QEGQVREQEGQVREQEGQVR---EQEGQVREQE 114
Query: 542 EQLPDQQAEDQQAKG---EQYPEGQSKDGQVKDQQTD-KEQNSKKQTQDQQTEDQPAQEK 597
Q+ +Q+ + ++ +G EQ + + ++GQV++Q+ +EQ + + Q+ Q +Q Q +
Sbjct: 115 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 174
Query: 598 KSPKGQF--QNVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQFHKGNLQAGQ 648
+ +GQ Q Q Q+ Q+ + + + E +Q + Q K Q G+
Sbjct: 175 EQ-EGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEE--QMQKQEEQMGE 224
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 52.4 bits (124), Expect = 1e-06
Identities = 70/381 (18%), Positives = 162/381 (42%), Gaps = 36/381 (9%)
Query: 291 SALKLEDISPEDLPSQALPVEGLSEQTMPSKSTSSHVKQSSNLTANDLPPQGILSQDTSS 350
SA+ + ++ +AL V +E +P ++ + + +N A LP G+L
Sbjct: 88 SAVVAQHLTNTVFVDRALIVVPYAEGVIPDEAKALSLLAPANAVAGLLPGGGLLPTP--- 144
Query: 351 QDMLFHDMTSQDMQSLDMLSQDTPSHAMPPQDIPSQDMLSQALSAHAILPEASTSHIVQF 410
+ +T L L T A+ +P ++ SQ+L+A +L ST
Sbjct: 145 -----NPLTQIGAVPLAALGAPTLDPALAALGLPGANLNSQSLAADQLLKLMSTVD---- 195
Query: 411 PEIQHLLQQ--PPDLQPENTEPQNQQILQM--SYQDIRSEVMEETKEWKSEEELHRRKSS 466
P++ H+ P L+ + + + ++ ++ Q + S +E K+ + R S
Sbjct: 196 PKLNHVAAGLVSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRS 255
Query: 467 RRH-----SLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQS-------PKQK 514
RR S ++++++ R HS + KS +R + +G +S K+K
Sbjct: 256 RRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKK 315
Query: 515 SLDQQIKDWLSPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQ-SKDGQVKDQQ 573
++ + PK +S ++++ + + ++ + K + P+ + S+ + +
Sbjct: 316 EDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHK 375
Query: 574 TDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQ 633
+K+++ K+ + E +++KKS + + ++++ +K K + +D + + Q
Sbjct: 376 KEKKKDKDKERSRDERERSTSKKKKSKDKE----KDRERKSESDKDVKQVTRDYDEEEQG 431
Query: 634 YQFWQFHKGN---LQAGQPRT 651
Y + K ++ G P+T
Sbjct: 432 YDSEKEKKEEKKPIETGSPKT 452
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 51.6 bits (122), Expect = 2e-06
Identities = 40/201 (19%), Positives = 94/201 (46%), Gaps = 19/201 (9%)
Query: 449 EETKEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLD----QQ 504
+E K W+ EE++H ++ R Q+ + + + + ++ K H + Q+
Sbjct: 435 QEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQE 494
Query: 505 SKGWQSPK------QKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQLPDQQA---EDQQAK 555
K W+ + +K +Q+ K W ++ +++ ++ + +E++ +Q+ E ++
Sbjct: 495 EKVWRQEEKMHDQEEKIREQEEKMWRQEEKIR-EQEEKIREQEEKIREQEEMMQEQEEKM 553
Query: 556 GEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQ 615
GEQ + Q ++ + ++ +EQ K + Q ++ +Q +EK + + Q E Q Q
Sbjct: 554 GEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQ--EEKIWEQEEKIREQEEMMQEQ 611
Query: 616 VEKV---PKLLCQDSESQIQQ 633
EK+ + +C+ E +Q
Sbjct: 612 EEKMWEQEEKMCEQEEKMQEQ 632
Score = 41.6 bits (96), Expect = 0.002
Identities = 42/234 (17%), Positives = 107/234 (45%), Gaps = 36/234 (15%)
Query: 429 EPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDV 488
E + Q+ ++ Q+ R E +E K W+ EE++ ++ R +Q K + + + +
Sbjct: 396 EEKRQEEEKIREQEKRQE--QEAKMWRQEEKIREQEEKIR----EQEKKM-WRQEEKIHE 448
Query: 489 QAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQLPDQQ 548
Q K ++ KR +Q + W+ +++ + +Q + W ++ ++ + + K +++
Sbjct: 449 QEKIREEEKRQ---EQEEMWR--QEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEK 503
Query: 549 AEDQQAK---------------GEQYPEGQSKDGQVKDQQTD-KEQNSKKQTQDQQTEDQ 592
DQ+ K EQ + + ++ ++++Q+ +EQ K Q+++ ++Q
Sbjct: 504 MHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQ 563
Query: 593 PAQEKKSPKGQFQNVQAEGQQAQV--------EKVPKLLCQDSESQIQQYQFWQ 638
++ K + Q + Q+ ++ E+ K+ Q+ Q Q+ + W+
Sbjct: 564 EKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWE 617
Score = 39.7 bits (91), Expect = 0.009
Identities = 28/151 (18%), Positives = 69/151 (45%), Gaps = 9/151 (5%)
Query: 449 EETKEWKSEEELHRRKSSRRHS---LNQQTKALQYLRRHSLDVQAKGQKSSK----RHSL 501
+E K W+ EE++ ++ R + +Q + +Q + + K Q+ K +
Sbjct: 514 QEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKI 573
Query: 502 DQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPE 561
+Q + + K+K +Q+ K W + + +Q ++ Q +E+ +Q E + E+ E
Sbjct: 574 REQEEKIREQKEKIREQEEKIW--EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 631
Query: 562 GQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQ 592
+ K + +++ ++E ++Q + Q +
Sbjct: 632 QEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
Score = 35.0 bits (79), Expect = 0.22
Identities = 51/284 (17%), Positives = 117/284 (41%), Gaps = 27/284 (9%)
Query: 352 DMLFHDMTSQ-DMQSLDMLSQDTPSHAMPPQDIPSQDMLSQALSAHAILPEASTSHI-VQ 409
D ++T + D SL++ + ++ Q+ L L E+ S I +
Sbjct: 192 DRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQ--------LVESEKSEIQLN 243
Query: 410 FPEIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRH 469
E++ L++ L P+ L Q + +++ + +E EL R
Sbjct: 244 VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE----NELWNR------ 293
Query: 470 SLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRH 529
LNQQ + + + + + + + + + +Q + + ++K Q+ W K
Sbjct: 294 -LNQQQEEKMWRQEEKIQ-EWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMW--EKEE 349
Query: 530 SVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQT 589
+ +Q ++ KE+ + E K E+ E + K + +Q+ +EQ K+Q +++
Sbjct: 350 KMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEK---MHEQEKIREQEEKRQEEEKIR 406
Query: 590 EDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQ 633
E + QE+++ + + E ++ E+ K+ Q+ + Q+
Sbjct: 407 EQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQE 450
Score = 34.7 bits (78), Expect = 0.29
Identities = 31/187 (16%), Positives = 91/187 (48%), Gaps = 18/187 (9%)
Query: 449 EETKEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGW 508
+E K + EE++H ++ R Q+ K R+ ++ + ++ + + +Q +
Sbjct: 375 KEEKIRELEEKMHEQEKIR----EQEEK-----RQEEEKIREQEKRQEQEAKMWRQEEKI 425
Query: 509 QSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQ 568
+ ++K +Q+ K W ++ + +Q ++ + +++ ++ Q+ K + E + +
Sbjct: 426 REQEEKIREQEKKMWRQEEK--IHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK 483
Query: 569 VKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSE 628
+ +Q+ ++Q K Q+++ DQ + ++ + ++ Q E + Q EK+ ++ E
Sbjct: 484 MHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWR--QEEKIREQEEKI-----REQE 536
Query: 629 SQIQQYQ 635
+I++ +
Sbjct: 537 EKIREQE 543
>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
Length = 715
Score = 50.8 bits (120), Expect = 4e-06
Identities = 58/235 (24%), Positives = 97/235 (41%), Gaps = 44/235 (18%)
Query: 423 LQPENTEP-QNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQQTKALQYL 481
+Q TE N + Q + S++ +++ +S + S+ QQ +ALQ
Sbjct: 2 MQESATETISNSSMNQNGMSTLSSQLDAGSRDGRSSGDTSSEVSTVELLHLQQQQALQAA 61
Query: 482 RRHSLDVQAKGQKSSKRHSLDQQ-------SKGWQSPK-------QKSLDQQIKDWLSP- 526
R+ L Q G KS K S D+Q S +P+ Q+ L QQ+ LSP
Sbjct: 62 RQLLLQQQTSGLKSPK--SSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQV---LSPQ 116
Query: 527 -----------------------KRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQ 563
K+ QL Q ++Q QQ + QQ + +Q + Q
Sbjct: 117 QLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQ 176
Query: 564 SKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEK 618
+ Q + QQ ++Q+ KQ ++QQ + Q Q+ + + FQ + QQ Q ++
Sbjct: 177 QQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQ 231
Score = 43.1 bits (100), Expect = 8e-04
Identities = 56/245 (22%), Positives = 100/245 (40%), Gaps = 24/245 (9%)
Query: 306 QALPVEGLSEQTMPSKSTSSHVKQSSNLTANDLPPQGILSQDTSSQDMLFHDMTSQDMQS 365
Q E +S +M S+ SS L A G S DTSS+ + Q Q+
Sbjct: 3 QESATETISNSSMNQNGMST---LSSQLDAGSR--DGRSSGDTSSEVSTVELLHLQQQQA 57
Query: 366 LD----MLSQDTPSHAMPPQDIPSQDMLSQALSAHAILPEASTSHIVQFPEIQHLLQQPP 421
L +L Q S P+ Q L +S + P+ T ++Q +LQQ
Sbjct: 58 LQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQ-----QMQQILQQ-- 110
Query: 422 DLQPENTEPQNQQILQMSYQDIRSEVMEETKEW--KSEEELHRRKSSRRHSLNQQTKALQ 479
+ PQ Q L Q + + ++ +E+ K +E+LH + ++ QQ + Q
Sbjct: 111 ----QVLSPQQLQALLQQQQAVMLQ-QQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQ 165
Query: 480 YLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQ-AQLN 538
++ Q + Q+ ++ QQ + K++ QQ + L+ ++ +Q Q+
Sbjct: 166 QQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQ 225
Query: 539 QTKEQ 543
Q ++Q
Sbjct: 226 QLQQQ 230
>gi|93141033 PAX interacting protein 1 [Homo sapiens]
Length = 1069
Score = 50.8 bits (120), Expect = 4e-06
Identities = 55/229 (24%), Positives = 93/229 (40%), Gaps = 48/229 (20%)
Query: 463 RKSSRRHSLNQQTKALQYLRR--HSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKS----- 515
+ S R + + A++ LR ++ D+Q + S+ H L S ++ +Q+
Sbjct: 320 QSSERSEMIATWSPAVRTLRNITNNADIQQMNRPSNVAHILQTLSAPTKNLEQQVNHSQQ 379
Query: 516 --------LDQQIKDWLSPKRHSVDKQAQLNQTKEQLPD-----------QQAEDQQAKG 556
L Q+K ++P+ H + +Q Q Q ++Q P QQ + QQ
Sbjct: 380 GHTNANAVLFSQVK--VTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQ 437
Query: 557 EQYPEGQS---KDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQ----- 608
+ YP+ Q + QQ Q S++Q Q Q + P Q+ P+ Q Q Q
Sbjct: 438 QPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHAL 497
Query: 609 ------------AEGQQAQVEKVPKLLCQDSESQIQQYQFWQFHKGNLQ 645
+ Q AQ+++ LL Q + QIQQ Q + H+ Q
Sbjct: 498 QQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQ 546
Score = 45.1 bits (105), Expect = 2e-04
Identities = 62/267 (23%), Positives = 99/267 (37%), Gaps = 51/267 (19%)
Query: 316 QTMPSKSTSSHVKQSSNLTANDLPPQGILSQD--TSSQDMLFHD--------MTSQDMQS 365
Q M S +H+ Q+ + +L Q SQ T++ +LF M Q Q+
Sbjct: 348 QQMNRPSNVAHILQTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQA 407
Query: 366 LDMLSQDTPSHAMPPQDIPSQDMLSQALSAHAILPEASTSHIVQFPEIQHLLQQPPDLQP 425
Q H P Q + Q Q +S QQP QP
Sbjct: 408 QQQQQQHPVLHLQPQQIMQLQQQQQQQIS-----------------------QQPYPQQP 444
Query: 426 ENTEPQNQQILQMSY--QDIRSEVMEETKEWKSEEELHRRKSS-----RRHSLNQQTKAL 478
+ Q QQ Q ++ Q + ++ ++ ++LHR + ++H+L QQ L
Sbjct: 445 PHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQL 504
Query: 479 QYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQK-------SLDQQIKDWLSPKRHSV 531
Q +H L Q Q ++HSL QQ + Q +Q+ QQ++ +P
Sbjct: 505 Q---QHQLQQQQLAQLQ-QQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQT 560
Query: 532 DKQAQLNQTKEQLPDQQAEDQQAKGEQ 558
+ Q +Q P QQ + Q Q
Sbjct: 561 SQALQHQVPPQQPPQQQQQQQPPPSPQ 587
Score = 35.4 bits (80), Expect = 0.17
Identities = 36/152 (23%), Positives = 60/152 (39%), Gaps = 15/152 (9%)
Query: 499 HSLDQQSKGWQSPKQKSL----DQQIKDWLSPKRHSVDKQAQLNQTKEQLPDQQAEDQQA 554
H L QQ + Q +Q + QQI ++ + +Q Q QQ + QQA
Sbjct: 399 HMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQA 458
Query: 555 KGEQYPEGQSKDGQVK---DQQTDKEQNSKKQTQDQ--------QTEDQPAQEKKSPKGQ 603
Q+ + Q + Q + QQ + Q + Q Q Q + Q+++ + Q
Sbjct: 459 HPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQ 518
Query: 604 FQNVQAEGQQAQVEKVPKLLCQDSESQIQQYQ 635
Q+ + QQ Q + +L + Q QQ Q
Sbjct: 519 QQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQ 550
>gi|48255931 hepatoma-derived growth factor-related protein 2
isoform 1 [Homo sapiens]
Length = 671
Score = 50.8 bits (120), Expect = 4e-06
Identities = 47/254 (18%), Positives = 109/254 (42%), Gaps = 7/254 (2%)
Query: 370 SQDTPSHAMPPQDIPSQDMLSQALSAHAILPEASTSHI-VQFPEIQHLLQQPPDLQPENT 428
+ D+ S A P ++++ S+ + +S S + V+ P + P +P
Sbjct: 231 ASDSDSKADSDGAKPEPVAMARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPKPRGR 290
Query: 429 EPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDV 488
+P+ ++ S D S+ ++ EWK +E RR+ R +Q + L+ LR +
Sbjct: 291 KPKPERPPSSSSSDSDSDEVDRISEWKRRDEARRRELEARRR-REQEEELRRLREQEKEE 349
Query: 489 QAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQLPDQQ 548
+ + ++ + R ++ S G + + D+ +K KR + + + P+ +
Sbjct: 350 KERRRERADRGEAERGSGGSSGDELREDDEPVK-----KRGRKGRGRGPPSSSDSEPEAE 404
Query: 549 AEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQ 608
E + K + P+ S + K Q +K +++ Q + + + +++ + V+
Sbjct: 405 LEREAKKSAKKPQSSSTEPARKPGQKEKRVRPEEKQQAKPVKVERTRKRSEGFSMDRKVE 464
Query: 609 AEGQQAQVEKVPKL 622
+ + + EK+ KL
Sbjct: 465 KKKEPSVEEKLQKL 478
>gi|14249158 hepatoma-derived growth factor-related protein 2
isoform 2 [Homo sapiens]
Length = 670
Score = 50.8 bits (120), Expect = 4e-06
Identities = 47/254 (18%), Positives = 109/254 (42%), Gaps = 7/254 (2%)
Query: 370 SQDTPSHAMPPQDIPSQDMLSQALSAHAILPEASTSHI-VQFPEIQHLLQQPPDLQPENT 428
+ D+ S A P ++++ S+ + +S S + V+ P + P +P
Sbjct: 231 ASDSDSKADSDGAKPEPVAMARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPKPRGR 290
Query: 429 EPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDV 488
+P+ ++ S D S+ ++ EWK +E RR+ R +Q + L+ LR +
Sbjct: 291 KPKPERPPSSSSSDSDSDEVDRISEWKRRDEARRRELEARRR-REQEEELRRLREQEKEE 349
Query: 489 QAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQLPDQQ 548
+ + ++ + R ++ S G + + D+ +K KR + + + P+ +
Sbjct: 350 KERRRERADRGEAERGSGGSSGDELREDDEPVK-----KRGRKGRGRGPPSSSDSEPEAE 404
Query: 549 AEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQ 608
E + K + P+ S + K Q +K +++ Q + + + +++ + V+
Sbjct: 405 LEREAKKSAKKPQSSSTEPARKPGQKEKRVRPEEKQQAKPVKVERTRKRSEGFSMDRKVE 464
Query: 609 AEGQQAQVEKVPKL 622
+ + + EK+ KL
Sbjct: 465 KKKEPSVEEKLQKL 478
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 50.4 bits (119), Expect = 5e-06
Identities = 35/211 (16%), Positives = 108/211 (51%), Gaps = 8/211 (3%)
Query: 429 EPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDV 488
E + Q+ +M Q+ ++ E+ + W+ +E++H ++ R + + + +R +
Sbjct: 469 EEKRQEQEEMWRQE--EKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKI 526
Query: 489 QAKGQKSSKRHS-LDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQLPDQ 547
+ + +K ++ + +Q + W+ +++ + +Q K W KR +++ ++ + +E++ +Q
Sbjct: 527 REQEEKMWRQEEKIREQEEMWR--EEEKMHEQEKIWEEEKRQ--EQEDKMWRQEEKIREQ 582
Query: 548 QAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNV 607
+ E + E+ E + K + +++ +E+ ++Q + Q +++ +E++ + + +
Sbjct: 583 E-EKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEM 641
Query: 608 QAEGQQAQVEKVPKLLCQDSESQIQQYQFWQ 638
E ++ E+ K+ Q+ + Q Q+ W+
Sbjct: 642 TQEQEEKMGEQEEKMCEQEEKMQEQEETMWR 672
Score = 47.0 bits (110), Expect = 6e-05
Identities = 35/198 (17%), Positives = 93/198 (46%), Gaps = 18/198 (9%)
Query: 449 EETKEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLD-----Q 503
+E K W+ EE++H ++ R Q+ + + + + ++ K H + Q
Sbjct: 449 QEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQ 508
Query: 504 QSKGW------QSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGE 557
+ K W + ++K +Q+ K W ++ + +Q ++ + +E++ +Q+ ++ K +
Sbjct: 509 EEKVWRQEEKIREQEEKIREQEEKMWRQEEK--IREQEEMWREEEKMHEQEKIWEEEKRQ 566
Query: 558 QYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVE 617
+ + + + +Q +K +++ ++Q+ + Q +EK + + Q E Q Q E
Sbjct: 567 EQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEE 626
Query: 618 KVPKLLCQDSESQIQQYQ 635
K+ ++ E +I++ +
Sbjct: 627 KI-----REQEEKIREQE 639
Score = 46.2 bits (108), Expect = 1e-04
Identities = 40/212 (18%), Positives = 97/212 (45%), Gaps = 16/212 (7%)
Query: 424 QPENTEPQNQQILQMSYQDIRSE--VMEETKEWKSEEELHRRKS-----SRRHSLNQQTK 476
Q E Q ++I + + R E + E+ + W+ EE++H ++ R+ ++ +
Sbjct: 515 QEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWR 574
Query: 477 ALQYLRRHSLDVQAKGQKSSKRHSL--DQQSKGWQSPK----QKSLDQQIKDWLSPKRHS 530
+ +R V + +K ++ +Q+ K W+ + Q+ Q+ ++ + +
Sbjct: 575 QEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEK 634
Query: 531 VDKQAQLNQTKEQLPDQQAE---DQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQ 587
+ +Q ++ Q +E+ +Q E +Q+ K ++ E + + +Q K + +++ ++Q
Sbjct: 635 IREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQ 694
Query: 588 QTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKV 619
+ Q +EK + + Q E Q Q EK+
Sbjct: 695 EEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM 726
Score = 45.4 bits (106), Expect = 2e-04
Identities = 43/209 (20%), Positives = 94/209 (44%), Gaps = 28/209 (13%)
Query: 449 EETKEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHS--------LDVQAKGQKSSKRHS 500
+E K W+ EE++ ++ R + + + +R + Q K + KR
Sbjct: 508 QEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQ- 566
Query: 501 LDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYP 560
+Q+ K W+ ++K +Q+ K W ++ + +Q + Q +E+ +Q E + + E+
Sbjct: 567 -EQEDKMWRQ-EEKIREQEEKVWRQEEK--IREQEEKRQEQEEKMWKQEEKIREQEEKIQ 622
Query: 561 EGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKV- 619
E + K +++Q+ +K + ++ TQ+Q+ + +EK + + Q E Q EK+
Sbjct: 623 EQEEK---IREQE-EKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIR 678
Query: 620 ----------PKLLCQDSESQIQQYQFWQ 638
K+ Q+ Q Q+ + W+
Sbjct: 679 EQEKKIREQEEKIREQEEMMQEQEEKMWE 707
Score = 40.4 bits (93), Expect = 0.005
Identities = 51/287 (17%), Positives = 120/287 (41%), Gaps = 19/287 (6%)
Query: 352 DMLFHDMTSQ-DMQSLDMLSQDTPSHAMPPQDIPSQDMLSQALSAHAILPEASTSHI-VQ 409
D ++T + D SL++ + ++ Q+ L L E+ S I +
Sbjct: 192 DRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQ--------LVESEKSEIQLN 243
Query: 410 FPEIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEV---MEETKEWKSEEELHRRKSS 466
E++ L++ L P+ L Q + +++ +EE + W + K
Sbjct: 244 VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMW 303
Query: 467 RRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSP 526
R+ Q+ + + + Q + + + Q+ W+ K++ + +Q ++ +
Sbjct: 304 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWE--KEEKMRRQ-EEMMWE 360
Query: 527 KRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQD 586
K + +Q ++ KE+ +Q E K E+ E + K + +Q+ +EQ K+Q ++
Sbjct: 361 KEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEK---MHEQEKIREQEEKRQEEE 417
Query: 587 QQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQ 633
+ E + QE+++ + + E ++ E+ K+ Q+ + Q+
Sbjct: 418 KIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQE 464
Score = 40.4 bits (93), Expect = 0.005
Identities = 25/156 (16%), Positives = 76/156 (48%), Gaps = 6/156 (3%)
Query: 449 EETKEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDVQAKGQK-SSKRHSLDQQSKG 507
+E K W+ EE++ ++ R+ + K + +R +Q + +K + + +Q +
Sbjct: 582 QEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEM 641
Query: 508 WQSPKQKSLDQQIK-----DWLSPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEG 562
Q ++K +Q+ K + + + ++ +Q + + +E+ +Q E + + E E
Sbjct: 642 TQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQ 701
Query: 563 QSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKK 598
+ K + +++ ++E+ ++Q + + +++ E++
Sbjct: 702 EEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 737
Score = 36.2 bits (82), Expect = 0.099
Identities = 43/222 (19%), Positives = 97/222 (43%), Gaps = 26/222 (11%)
Query: 426 ENTEPQNQQILQMSYQDIRSEVMEETKEWKS---EEELHRRKSSRRHSLNQQTKALQYLR 482
E Q + + + + R E M KE K EE++H ++ R +Q
Sbjct: 363 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE------- 415
Query: 483 RHSLDVQAKGQKSSKRHSLDQQSKGW-QSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTK 541
+ K ++ KR +Q++K W Q K + +++I++ +K + + +
Sbjct: 416 ------EEKIREQEKRQ--EQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIR 467
Query: 542 EQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPK 601
E+ Q+ E+ + E+ E Q + + K++ ++E+ +KQ + +++ +E++
Sbjct: 468 EEEKRQEQEEMWRQEEKIHE-QEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKI 526
Query: 602 GQFQNVQAEGQQAQVEKV--PKLLCQDSESQIQQYQFWQFHK 641
+ Q E Q EK+ + + ++ E +Q + W+ K
Sbjct: 527 RE----QEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEK 564
Score = 33.5 bits (75), Expect = 0.64
Identities = 35/210 (16%), Positives = 92/210 (43%), Gaps = 12/210 (5%)
Query: 441 QDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDVQAK-----GQKS 495
Q + + ++ K + EEL + + + L + T + L+ + +Q K +KS
Sbjct: 179 QALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKS 238
Query: 496 SKRHSLDQQSKGWQSPKQKSLDQQIK---DWLSPKRHSVDKQAQL----NQTKEQLPDQQ 548
+ ++ + + + K QQ++ D L + SV + Q N+ +L QQ
Sbjct: 239 EIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQ 298
Query: 549 AEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQ 608
E + E+ E + K + +++ ++E+ ++Q + + +++ EK+ + + +
Sbjct: 299 EEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM 358
Query: 609 AEGQQAQVEKVPKLLCQDSESQIQQYQFWQ 638
E ++ + + ++ + + Q+ W+
Sbjct: 359 WEKEEKMRRQEEMMWEKEEKMRRQEEMMWE 388
Score = 33.5 bits (75), Expect = 0.64
Identities = 31/173 (17%), Positives = 80/173 (46%), Gaps = 14/173 (8%)
Query: 424 QPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRK---SSRRHSLNQQTKALQY 480
Q E Q ++I + ++ R E +E K WK EE++ ++ + + +Q + ++
Sbjct: 582 QEEKVWRQEEKIREQ--EEKRQE--QEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIRE 637
Query: 481 LRRHSLDVQAK-GQKSSK----RHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQA 535
+ + + K G++ K + +Q + ++K +Q+ K + + + +Q
Sbjct: 638 QEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKK--IREQEEKIREQE 695
Query: 536 QLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQ 588
++ Q +E+ +Q E + E+ E + K + +++ ++E ++Q + Q
Sbjct: 696 EMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 748
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 50.4 bits (119), Expect = 5e-06
Identities = 36/207 (17%), Positives = 97/207 (46%), Gaps = 18/207 (8%)
Query: 449 EETKEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLD-----Q 503
+E K W+ EE++H ++ R Q+ + + + + ++ K H + Q
Sbjct: 496 QEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQ 555
Query: 504 QSKGWQSPK------QKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQLPDQQ--AEDQQAK 555
+ K W+ + +K +Q+ K W ++ +++ ++ + +E++ +Q+ ++Q+ K
Sbjct: 556 EEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIR-EQEEKIREQEEKIREQEEMTQEQEEK 614
Query: 556 GEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQ 615
+ E + + +Q +K + +++ ++Q+ + + +EK + + Q E Q
Sbjct: 615 MGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQ 674
Query: 616 VEKV----PKLLCQDSESQIQQYQFWQ 638
EK+ K+ Q+ + + Q+ + W+
Sbjct: 675 EEKMCEQEEKMQEQEEKMRRQEEKMWE 701
Score = 47.8 bits (112), Expect = 3e-05
Identities = 43/194 (22%), Positives = 98/194 (50%), Gaps = 17/194 (8%)
Query: 429 EPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDV 488
E + Q+ ++ Q+ R E +E K W+ EE++ ++ R Q+ K + + +
Sbjct: 457 EEKRQEEEKIREQEKRQE--QEAKMWRQEEKIREQEEKIRE---QEEK--MWRQEEKIHE 509
Query: 489 QAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKR-HSVDKQAQLNQTKEQLPDQ 547
Q K ++ KR +Q + W+ +++ + +Q + W ++ H +++ + + K ++
Sbjct: 510 QEKIREEEKRQ---EQEEMWR--QEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEE 564
Query: 548 QAEDQQAK-GEQYPEGQSKDGQVKDQQTD-KEQNSKKQTQDQQTEDQPAQEKKSPKGQFQ 605
+ DQ+ K EQ + ++ ++++Q+ +EQ K + Q++ T++Q +EK + +
Sbjct: 565 KMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQ--EEKMGEQEEKM 622
Query: 606 NVQAEGQQAQVEKV 619
Q E Q Q EK+
Sbjct: 623 CEQEEKMQEQEEKM 636
Score = 42.4 bits (98), Expect = 0.001
Identities = 24/165 (14%), Positives = 80/165 (48%), Gaps = 1/165 (0%)
Query: 449 EETKEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGW 508
+E K W+ EE++H ++ R + + + +R ++ + +K ++ + Q+ +
Sbjct: 555 QEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEK 614
Query: 509 QSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQ 568
+++ + +Q ++ + + + +Q + + +E+ +Q E + + E E + K +
Sbjct: 615 MGEQEEKMCEQ-EEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 673
Query: 569 VKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQ 613
+++ ++E+ ++Q + + +++ E++ Q + E Q+
Sbjct: 674 QEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 718
Score = 37.7 bits (86), Expect = 0.034
Identities = 52/284 (18%), Positives = 118/284 (41%), Gaps = 27/284 (9%)
Query: 352 DMLFHDMTSQ-DMQSLDMLSQDTPSHAMPPQDIPSQDMLSQALSAHAILPEASTSHI-VQ 409
D ++T + D SL++ + ++ Q+ L L E+ S I +
Sbjct: 253 DRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQ--------LVESEKSEIQLN 304
Query: 410 FPEIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRH 469
E++ L++ L P+ L Q + +++ + +E EL R
Sbjct: 305 VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE----NELWNR------ 354
Query: 470 SLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRH 529
LNQQ + + + + + + + + + +Q + + ++K Q+ W K
Sbjct: 355 -LNQQQEEKMWRQEEKIQ-EWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMW--EKEE 410
Query: 530 SVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQT 589
+ +Q ++ KE+ +Q E K E+ E + K + +Q+ +EQ K+Q +++
Sbjct: 411 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEK---MHEQEKIREQEEKRQEEEKIR 467
Query: 590 EDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQ 633
E + QE+++ + + E ++ E+ K+ Q+ + Q+
Sbjct: 468 EQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQE 511
Score = 36.2 bits (82), Expect = 0.099
Identities = 41/240 (17%), Positives = 103/240 (42%), Gaps = 34/240 (14%)
Query: 426 ENTEPQNQQILQMSYQDIRSEVMEETKEWKS---EEELHRRKSSRRHSLNQQ--TKALQY 480
E Q + + + + R E M KE K EE++H ++ R +Q K +
Sbjct: 410 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 469
Query: 481 LRRHSLDVQAKGQKSSKRHS----LDQQSKGWQSPKQKSLDQQIKD----------WLSP 526
+R + + Q+ R +Q+ K W+ ++ ++I++ W
Sbjct: 470 EKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE 529
Query: 527 KRHSVDKQAQLNQTKEQLPDQ-------------QAEDQQAKGEQYPEGQSKDGQVKDQQ 573
++ + +Q ++ + KE++ +Q Q E + E+ E + K + +++
Sbjct: 530 EK--IREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKI 587
Query: 574 TDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQ 633
++E+ ++Q + + +++ QE++ G+ + E ++ E+ K+ Q+ + + Q+
Sbjct: 588 REQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQE 647
Score = 34.7 bits (78), Expect = 0.29
Identities = 38/197 (19%), Positives = 95/197 (48%), Gaps = 22/197 (11%)
Query: 449 EETKEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGW 508
+E K + EE++ ++ R + + +RR + K +K + Q+ W
Sbjct: 380 QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRR-----QEEMMW 434
Query: 509 QSPKQKSLDQQIKDWLSPKRHSVDK---QAQLNQTKEQLPDQQ-AEDQQAK-GEQYPEGQ 563
+ +++I++ L K H +K Q + Q +E++ +Q+ ++Q+AK Q + +
Sbjct: 435 EK------EEKIRE-LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR 487
Query: 564 SKDGQVKDQQTDK-EQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQ-QAQVEKVPK 621
++ ++++Q+ Q K Q++ E++ QE++ Q + ++ + + Q EK+ +
Sbjct: 488 EQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHE 547
Query: 622 LLCQDSESQIQQYQFWQ 638
Q+ + + Q+ + W+
Sbjct: 548 ---QEEKIRKQEEKMWR 561
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 50.1 bits (118), Expect = 7e-06
Identities = 38/213 (17%), Positives = 98/213 (46%), Gaps = 8/213 (3%)
Query: 414 QHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVM---EETKEWKSEEELHRRKSSRRHS 470
+ + +Q L+ + + Q+ + + +R E +E K W EE++ + R
Sbjct: 507 ERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMRERE 566
Query: 471 LNQQTKALQYLRRHSLDVQAKGQKSSKRHS-LDQQSKGWQSPKQKSLDQQIKDWLSPKRH 529
+ + + +R +Q + +K ++ + +Q + Q ++K +Q+ K W +
Sbjct: 567 KKMREEE-EMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEED 625
Query: 530 SVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQT 589
+ +Q ++ +E+ +Q E + E+ E + K + +++ +E+ ++Q + Q
Sbjct: 626 KMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQG 685
Query: 590 EDQPAQEKKSP-KGQFQNV--QAEGQQAQVEKV 619
+++ +E++ +GQ + + Q E Q EK+
Sbjct: 686 QEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKM 718
Score = 48.5 bits (114), Expect = 2e-05
Identities = 39/233 (16%), Positives = 104/233 (44%), Gaps = 12/233 (5%)
Query: 414 QHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSS---RRHS 470
+ L +Q +L+ + E + Q+ L+ + ++ + E K W+ EE++ ++ +
Sbjct: 283 KRLREQEKELREQEKELREQKKLREQEEQMQEQ---EEKMWEQEEKMREQEEKMWRQEER 339
Query: 471 LNQQTKALQYLRRHSLDVQAKGQKSSKR-----HSLDQQSKGWQSPKQKSLDQQIKDWLS 525
L +Q K ++ + D + + + +R + +Q K W+ ++ +++I++
Sbjct: 340 LWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREK 399
Query: 526 PKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQ 585
R + + + ++ + E ++ + +Q + K+ ++ +Q+ +EQ K Q
Sbjct: 400 KMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKE-KLWEQEKMQEQEEKIWEQ 458
Query: 586 DQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQ 638
+++ DQ + K Q E + E+ K+ Q+ + Q+ + W+
Sbjct: 459 EEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWE 511
Score = 48.1 bits (113), Expect = 3e-05
Identities = 59/273 (21%), Positives = 122/273 (44%), Gaps = 45/273 (16%)
Query: 411 PEIQ-HLLQQPPDLQPENTEPQNQQILQMSYQDIRSE--VMEETKEWKSEEELHRRKSSR 467
P++Q + LQ+ Q E Q ++I + + R E + E+ + + +EE RR+ R
Sbjct: 225 PQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKR 284
Query: 468 ----RHSLNQQTKALQY---LRRHSLDVQAKGQK--SSKRHSLDQQSKGWQSPK------ 512
L +Q K L+ LR +Q + +K + +Q+ K W+ +
Sbjct: 285 LREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE 344
Query: 513 -------QKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQLPDQ----QAEDQQAKGEQYPE 561
QK DQ+ + W ++ +L + +E++ +Q + E++ + E+ E
Sbjct: 345 KQMREQEQKMRDQEERMW--------EQDERLREKEERMREQEKMWEQEEKMQEEERIRE 396
Query: 562 GQSKDGQVKDQQTDKEQNSKKQTQDQ---QTEDQPAQEKKSPKGQFQNVQAEGQQAQVEK 618
+ K ++++T +EQ K Q Q++ + E++ Q+++ P+ + + + E Q Q EK
Sbjct: 397 REKK--MREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEK 454
Query: 619 V---PKLLCQDSESQIQQYQFWQFHKGNLQAGQ 648
+ + + E Q+ + W+ K Q Q
Sbjct: 455 IWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQ 487
Score = 46.6 bits (109), Expect = 7e-05
Identities = 46/223 (20%), Positives = 99/223 (44%), Gaps = 26/223 (11%)
Query: 424 QPENTEPQNQQILQMSYQDIRSEVMEETKE--WKSEEELHRRKSSRRHSLNQQTKALQYL 481
+ E E Q Q++ + + E M+E +E W+ EE++ + Q+ K +
Sbjct: 424 EQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIR----DQEEMWGQEKKMWRQE 479
Query: 482 RRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDW-----LSPKRHSVDKQAQ 536
+ + Q Q+ R DQ+ K W DQ+ + W L K + +Q +
Sbjct: 480 KMREQEDQMWEQEEKMR---DQEQKMW--------DQEERMWEQDERLREKEERMREQKK 528
Query: 537 LNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQE 596
+ Q +E++ +++ +Q K E + ++ + ++ K + ++ ++Q+ + Q +E
Sbjct: 529 MWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEE 588
Query: 597 KKSPKGQFQNVQAEGQQAQVEKV----PKLLCQDSESQIQQYQ 635
K + + Q E Q Q EK+ K+ Q+ E ++Q+ +
Sbjct: 589 KMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQE 631
Score = 41.6 bits (96), Expect = 0.002
Identities = 37/227 (16%), Positives = 105/227 (46%), Gaps = 14/227 (6%)
Query: 412 EIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSE--VMEETKEWKSEEELHRRKSSRRH 469
E + + QQ ++ E + ++ + +R E + E K+ + EEE+ R + +
Sbjct: 525 EQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEK-- 582
Query: 470 SLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRH 529
+ +Q + ++ + + K Q+ ++ +Q+ K W+ ++ + +Q + +
Sbjct: 583 -MQEQEEKMREQEEKMWEQEEKMQEQEEK-MWEQEEKMWEQEEEDKMQEQEEMMWEQEEK 640
Query: 530 SVDKQAQLNQTKEQLPDQQA----EDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQ 585
+++ ++ + +E++ +Q+ ++++ +G++ + ++ ++ +EQ K + Q
Sbjct: 641 MQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQ 700
Query: 586 DQ----QTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSE 628
++ Q E QE+K + + E + Q EK+ + L + E
Sbjct: 701 EEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEE 747
Score = 40.8 bits (94), Expect = 0.004
Identities = 51/257 (19%), Positives = 107/257 (41%), Gaps = 42/257 (16%)
Query: 424 QPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEE-LHRRKSSRRHSLNQQTKALQYLR 482
Q E Q++++ + + E M E +E EEE + R+ R + + ++
Sbjct: 357 QEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQ 416
Query: 483 RHSLDVQAKGQKSSKRHSL-DQQSKGWQSPKQKSLDQQI------------------KDW 523
+ ++ + +K ++ L +Q+ K W+ K + +++I K W
Sbjct: 417 KQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMW 476
Query: 524 LSPKRHSVDKQAQLNQTKEQLPDQQAEDQQAK-GEQYPEGQSKDGQVKDQ---------- 572
K + Q + K + +Q+ DQ+ + EQ + K+ ++++Q
Sbjct: 477 RQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKM 536
Query: 573 -QTDKEQNSKKQTQDQQ---TEDQPAQE---KKSPKGQFQNVQAEGQQAQVEKV----PK 621
+ K Q +K+T DQ+ E++ +E K + + Q E Q Q EK+ K
Sbjct: 537 REEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEK 596
Query: 622 LLCQDSESQIQQYQFWQ 638
+ Q+ + Q Q+ + W+
Sbjct: 597 MWEQEEKMQEQEEKMWE 613
>gi|8923206 membrane-spanning 4-domains, subfamily A, member 12
[Homo sapiens]
Length = 267
Score = 49.7 bits (117), Expect = 9e-06
Identities = 29/97 (29%), Positives = 46/97 (47%), Gaps = 22/97 (22%)
Query: 39 KGEPRVLGATQILLALIIVGFGTIFALNYIGFSQRL---PLVVLTGYPFWGAL------- 88
K E + LG QI++ L+ +GFG + L F + L V+ GYPFWG L
Sbjct: 85 KEEAKALGVIQIMVGLMHIGFGIVLCLISFSFREVLGFASTAVIGGYPFWGGLSFIISGS 144
Query: 89 ------------IGQGVTGMNVISSLVAITGITFTIL 113
+ +G GMN++SS++A G+ ++
Sbjct: 145 LSVSASKELSRCLVKGSLGMNIVSSILAFIGVILLLV 181
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.354
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,651,214
Number of Sequences: 37866
Number of extensions: 1225892
Number of successful extensions: 8617
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 129
Number of HSP's successfully gapped in prelim test: 711
Number of HSP's that attempted gapping in prelim test: 5954
Number of HSP's gapped (non-prelim): 2393
length of query: 662
length of database: 18,247,518
effective HSP length: 109
effective length of query: 553
effective length of database: 14,120,124
effective search space: 7808428572
effective search space used: 7808428572
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.