Search of human proteins with 239753442

Search of human proteins with 239753442

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239753442 PREDICTED: HEAT repeat containing 7B1 [Homo
sapiens]
         (1723 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239753442 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]    3392   0.0  
gi|239748007 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]    3306   0.0  
gi|239741905 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]    3289   0.0  
gi|154240671 HEAT repeat family member 7B2 [Homo sapiens]             644   0.0  
gi|150010654 HEAT repeat containing 7A isoform 1 [Homo sapiens]       596   e-170
gi|113420243 PREDICTED: hypothetical protein LOC377711 isoform 5...   441   e-123
gi|148727311 hypothetical protein LOC389690 [Homo sapiens]            202   3e-51
gi|223278410 hypothetical protein LOC374977 [Homo sapiens]            167   8e-41
gi|194595501 hypothetical protein LOC140699 isoform 1 [Homo sapi...   154   7e-37
gi|149944578 HEAT repeat containing 7A isoform 2 [Homo sapiens]       150   8e-36
gi|149944469 HEAT repeat containing 7A isoform 2 [Homo sapiens]       150   8e-36
gi|154937380 hypothetical protein LOC642475 [Homo sapiens]            116   2e-25
gi|187761381 maestro isoform d [Homo sapiens]                         100   2e-20
gi|187761375 maestro isoform a [Homo sapiens]                         100   2e-20
gi|47578111 hypothetical protein LOC140699 isoform 2 [Homo sapiens]    91   7e-18
gi|47578113 hypothetical protein LOC140699 isoform 3 [Homo sapiens]    68   7e-11
gi|187761379 maestro isoform c [Homo sapiens]                          55   8e-07
gi|187761377 maestro isoform b [Homo sapiens]                          55   8e-07
gi|117956387 hypothetical protein LOC80133 [Homo sapiens]              47   1e-04
gi|21071077 dishevelled-associated activator of morphogenesis 1 ...    35   0.48 
gi|57634534 nucleoporin 205kDa [Homo sapiens]                          35   0.63 
gi|22749269 ring finger protein 129 [Homo sapiens]                     34   1.1  
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]         34   1.1  
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]         34   1.1  
gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]         34   1.1  
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]         34   1.1  
gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]         34   1.1  
gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]         34   1.1  
gi|32526896 armadillo repeat containing 8 isoform 2 [Homo sapiens]     34   1.4  
gi|12083581 phosphoinositide-specific phospholipase C beta 1 iso...    32   7.0  

>gi|239753442 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]
          Length = 1723

 Score = 3392 bits (8794), Expect = 0.0
 Identities = 1723/1723 (100%), Positives = 1723/1723 (100%)

Query: 1    MCIGPRAELFLVVNICLIQKKTLRKELEEEMTEAITEAAVDSSEEVSEERDDLGPLELHD 60
            MCIGPRAELFLVVNICLIQKKTLRKELEEEMTEAITEAAVDSSEEVSEERDDLGPLELHD
Sbjct: 1    MCIGPRAELFLVVNICLIQKKTLRKELEEEMTEAITEAAVDSSEEVSEERDDLGPLELHD 60

Query: 61   SGTFQQVVNLLDIIDSESAKTDTTGAGLDMRKTLASVIIMEKATTEPSVVINTLIRCLQV 120
            SGTFQQVVNLLDIIDSESAKTDTTGAGLDMRKTLASVIIMEKATTEPSVVINTLIRCLQV
Sbjct: 61   SGTFQQVVNLLDIIDSESAKTDTTGAGLDMRKTLASVIIMEKATTEPSVVINTLIRCLQV 120

Query: 121  PEISTQRKVNIYNILQDIIQQEGELEEQCVQRLVAIASKEMREIPEMEGYMKAEVASDTL 180
            PEISTQRKVNIYNILQDIIQQEGELEEQCVQRLVAIASKEMREIPEMEGYMKAEVASDTL
Sbjct: 121  PEISTQRKVNIYNILQDIIQQEGELEEQCVQRLVAIASKEMREIPEMEGYMKAEVASDTL 180

Query: 181  VALSRNHFSLVMYELQHHLKPLNLTDEFVIITLAKLANGNVFEFMPYMGITLATIFTMLR 240
            VALSRNHFSLVMYELQHHLKPLNLTDEFVIITLAKLANGNVFEFMPYMGITLATIFTMLR
Sbjct: 181  VALSRNHFSLVMYELQHHLKPLNLTDEFVIITLAKLANGNVFEFMPYMGITLATIFTMLR 240

Query: 241  LANEAKIRQAICSAMETFCETVQFYLKHLEESVYPVMTEEEFALKVFPMYRYFVTVWLRH 300
            LANEAKIRQAICSAMETFCETVQFYLKHLEESVYPVMTEEEFALKVFPMYRYFVTVWLRH
Sbjct: 241  LANEAKIRQAICSAMETFCETVQFYLKHLEESVYPVMTEEEFALKVFPMYRYFVTVWLRH 300

Query: 301  HNPEVKLGVIKSLKPMLGLLLPNDDLREQVYDYIPLLLAEYQGKGHLPPFANPLQVLRQI 360
            HNPEVKLGVIKSLKPMLGLLLPNDDLREQVYDYIPLLLAEYQGKGHLPPFANPLQVLRQI
Sbjct: 301  HNPEVKLGVIKSLKPMLGLLLPNDDLREQVYDYIPLLLAEYQGKGHLPPFANPLQVLRQI 360

Query: 361  LGLSVTTNTPVPQMQLHTIFTELHVQVCNKAPAQHQYSSQNLMEMVHCFVALARSYPKEL 420
            LGLSVTTNTPVPQMQLHTIFTELHVQVCNKAPAQHQYSSQNLMEMVHCFVALARSYPKEL
Sbjct: 361  LGLSVTTNTPVPQMQLHTIFTELHVQVCNKAPAQHQYSSQNLMEMVHCFVALARSYPKEL 420

Query: 421  MKFFFSQMETNKEAVRVGTLNLIRAIVSADEPRMSIRAIYLAIRVVKNTISDTRSKVRMA 480
            MKFFFSQMETNKEAVRVGTLNLIRAIVSADEPRMSIRAIYLAIRVVKNTISDTRSKVRMA
Sbjct: 421  MKFFFSQMETNKEAVRVGTLNLIRAIVSADEPRMSIRAIYLAIRVVKNTISDTRSKVRMA 480

Query: 481  ILHIIGQLALCGYQERIKGWGLKYLSVQLTLSTYKLTNRREKFYQRDLEERMVHKVTMDT 540
            ILHIIGQLALCGYQERIKGWGLKYLSVQLTLSTYKLTNRREKFYQRDLEERMVHKVTMDT
Sbjct: 481  ILHIIGQLALCGYQERIKGWGLKYLSVQLTLSTYKLTNRREKFYQRDLEERMVHKVTMDT 540

Query: 541  VKIITSSVSGMTTEFWVRLLCYIMETDYVEALTPICISLTNLAEHQLHGQDVDVSVAGKS 600
            VKIITSSVSGMTTEFWVRLLCYIMETDYVEALTPICISLTNLAEHQLHGQDVDVSVAGKS
Sbjct: 541  VKIITSSVSGMTTEFWVRLLCYIMETDYVEALTPICISLTNLAEHQLHGQDVDVSVAGKS 600

Query: 601  RQVDLPAPQKLLARLLVLMSSPYKGEGRGIAMLNLLRTLSQSIAPSMADMWELEIALLVR 660
            RQVDLPAPQKLLARLLVLMSSPYKGEGRGIAMLNLLRTLSQSIAPSMADMWELEIALLVR
Sbjct: 601  RQVDLPAPQKLLARLLVLMSSPYKGEGRGIAMLNLLRTLSQSIAPSMADMWELEIALLVR 660

Query: 661  YLEEHTEFTWDQKAWEDKLIQFLRNSLKKTRGSSWSLRLSKELNNQIASFDSPSLEKGFL 720
            YLEEHTEFTWDQKAWEDKLIQFLRNSLKKTRGSSWSLRLSKELNNQIASFDSPSLEKGFL
Sbjct: 661  YLEEHTEFTWDQKAWEDKLIQFLRNSLKKTRGSSWSLRLSKELNNQIASFDSPSLEKGFL 720

Query: 721  YRALGFTLATGLEASKVEVLLLELLYKTDYSNDFDSEGVIMCFGLCARGQVKTVLNVLHD 780
            YRALGFTLATGLEASKVEVLLLELLYKTDYSNDFDSEGVIMCFGLCARGQVKTVLNVLHD
Sbjct: 721  YRALGFTLATGLEASKVEVLLLELLYKTDYSNDFDSEGVIMCFGLCARGQVKTVLNVLHD 780

Query: 781  FEERIQESEQSWQISAWRKDHPWRRETVKSALMVMYSCVASYCHPQLLLNLVDSPITAKI 840
            FEERIQESEQSWQISAWRKDHPWRRETVKSALMVMYSCVASYCHPQLLLNLVDSPITAKI
Sbjct: 781  FEERIQESEQSWQISAWRKDHPWRRETVKSALMVMYSCVASYCHPQLLLNLVDSPITAKI 840

Query: 841  IHHYVSSCQDICLKMAFMKSVVQVTKAINNIKDLEDFHFAQKTTLTSIIVAVIKAEPTDN 900
            IHHYVSSCQDICLKMAFMKSVVQVTKAINNIKDLEDFHFAQKTTLTSIIVAVIKAEPTDN
Sbjct: 841  IHHYVSSCQDICLKMAFMKSVVQVTKAINNIKDLEDFHFAQKTTLTSIIVAVIKAEPTDN 900

Query: 901  LVSPVRALAMEALSHLSKLKPFYSTEENSELMDISIHSVISLQLPGEDNESIKTLYANAL 960
            LVSPVRALAMEALSHLSKLKPFYSTEENSELMDISIHSVISLQLPGEDNESIKTLYANAL
Sbjct: 901  LVSPVRALAMEALSHLSKLKPFYSTEENSELMDISIHSVISLQLPGEDNESIKTLYANAL 960

Query: 961  SSLEQLMESLLQRQLDPKGLQEMVQLLEKWILSEKEWEREKAVSLHLYLMRIYVHSTAVC 1020
            SSLEQLMESLLQRQLDPKGLQEMVQLLEKWILSEKEWEREKAVSLHLYLMRIYVHSTAVC
Sbjct: 961  SSLEQLMESLLQRQLDPKGLQEMVQLLEKWILSEKEWEREKAVSLHLYLMRIYVHSTAVC 1020

Query: 1021 IHLKLGQFGTMVGLIAPCTCDAHQRTRMASMNVLSSLLDLHASQTCSLWGPSKQKELEKC 1080
            IHLKLGQFGTMVGLIAPCTCDAHQRTRMASMNVLSSLLDLHASQTCSLWGPSKQKELEKC
Sbjct: 1021 IHLKLGQFGTMVGLIAPCTCDAHQRTRMASMNVLSSLLDLHASQTCSLWGPSKQKELEKC 1080

Query: 1081 KGDLQSTDVEKIFCASSRIAKVVCMEFSCDEVVSLIQKLCENTGAMNLQHDKASVTWIAS 1140
            KGDLQSTDVEKIFCASSRIAKVVCMEFSCDEVVSLIQKLCENTGAMNLQHDKASVTWIAS
Sbjct: 1081 KGDLQSTDVEKIFCASSRIAKVVCMEFSCDEVVSLIQKLCENTGAMNLQHDKASVTWIAS 1140

Query: 1141 FLQMRAKELEDKVAEILSAILVHLPVVDHPEVRRLLIDGILLLAHHHQETILTSLLRQPL 1200
            FLQMRAKELEDKVAEILSAILVHLPVVDHPEVRRLLIDGILLLAHHHQETILTSLLRQPL
Sbjct: 1141 FLQMRAKELEDKVAEILSAILVHLPVVDHPEVRRLLIDGILLLAHHHQETILTSLLRQPL 1200

Query: 1201 PMESHLAEVWLAVSENVPFARTMLHSLMGRLQSRLSPRISATSKADIWRLAAVDPLMTLC 1260
            PMESHLAEVWLAVSENVPFARTMLHSLMGRLQSRLSPRISATSKADIWRLAAVDPLMTLC
Sbjct: 1201 PMESHLAEVWLAVSENVPFARTMLHSLMGRLQSRLSPRISATSKADIWRLAAVDPLMTLC 1260

Query: 1261 TIHLLIQKLDENDKLPDFLPDLIYTLLLQLGSSHRPEAAPPVLKMWKLVHTTPLPEEMNL 1320
            TIHLLIQKLDENDKLPDFLPDLIYTLLLQLGSSHRPEAAPPVLKMWKLVHTTPLPEEMNL
Sbjct: 1261 TIHLLIQKLDENDKLPDFLPDLIYTLLLQLGSSHRPEAAPPVLKMWKLVHTTPLPEEMNL 1320

Query: 1321 QRCSRGRVTIKSMQLLFKRVKSQHLAHTLDEQAVWDLLQDGGTFLEGVSLLARLCMQHVE 1380
            QRCSRGRVTIKSMQLLFKRVKSQHLAHTLDEQAVWDLLQDGGTFLEGVSLLARLCMQHVE
Sbjct: 1321 QRCSRGRVTIKSMQLLFKRVKSQHLAHTLDEQAVWDLLQDGGTFLEGVSLLARLCMQHVE 1380

Query: 1381 GHRQRLAELVLRGMDSEVLSCRISSTAVCVEFMSGPVLYQEKLLKPAALLLEKGADQEED 1440
            GHRQRLAELVLRGMDSEVLSCRISSTAVCVEFMSGPVLYQEKLLKPAALLLEKGADQEED
Sbjct: 1381 GHRQRLAELVLRGMDSEVLSCRISSTAVCVEFMSGPVLYQEKLLKPAALLLEKGADQEED 1440

Query: 1441 EALRVLSLRALGNMALGAPKKVKQYRKVLLEKCLGPLREPVSNSVTAEGMEALTKILAEL 1500
            EALRVLSLRALGNMALGAPKKVKQYRKVLLEKCLGPLREPVSNSVTAEGMEALTKILAEL
Sbjct: 1441 EALRVLSLRALGNMALGAPKKVKQYRKVLLEKCLGPLREPVSNSVTAEGMEALTKILAEL 1500

Query: 1501 REGDVGSSFDAMSEQCRIFFDNESELLRLKAFILFGKLARVVGMSKKHFFKGEVKKAWIP 1560
            REGDVGSSFDAMSEQCRIFFDNESELLRLKAFILFGKLARVVGMSKKHFFKGEVKKAWIP
Sbjct: 1501 REGDVGSSFDAMSEQCRIFFDNESELLRLKAFILFGKLARVVGMSKKHFFKGEVKKAWIP 1560

Query: 1561 LMLHSQDPCSNAAQACMATMFQCVHFWGWKSLEHPSGPSDTTTDDKMTIFQTTMCSILVR 1620
            LMLHSQDPCSNAAQACMATMFQCVHFWGWKSLEHPSGPSDTTTDDKMTIFQTTMCSILVR
Sbjct: 1561 LMLHSQDPCSNAAQACMATMFQCVHFWGWKSLEHPSGPSDTTTDDKMTIFQTTMCSILVR 1620

Query: 1621 KPKGEPAHSEKPAVLYRFLLXTMAYVKNNLSRIRIAACNLAGIIMKQMSTHYLKKLDFPA 1680
            KPKGEPAHSEKPAVLYRFLL TMAYVKNNLSRIRIAACNLAGIIMKQMSTHYLKKLDFPA
Sbjct: 1621 KPKGEPAHSEKPAVLYRFLLXTMAYVKNNLSRIRIAACNLAGIIMKQMSTHYLKKLDFPA 1680

Query: 1681 LRNSLQELQLDPDPGVRRAALETLTVLDSCSQHGFLASPQGMS 1723
            LRNSLQELQLDPDPGVRRAALETLTVLDSCSQHGFLASPQGMS
Sbjct: 1681 LRNSLQELQLDPDPGVRRAALETLTVLDSCSQHGFLASPQGMS 1723


>gi|239748007 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]
          Length = 1706

 Score = 3306 bits (8572), Expect = 0.0
 Identities = 1693/1723 (98%), Positives = 1694/1723 (98%), Gaps = 17/1723 (0%)

Query: 1    MCIGPRAELFLVVNICLIQKKTLRKELEEEMTEAITEAAVDSSEEVSEERDDLGPLELHD 60
            MCIGPRAELFLVVNICLIQKKTLRKELEEEMTEAITEAAVDSSEEVSEERDDLGPLELHD
Sbjct: 1    MCIGPRAELFLVVNICLIQKKTLRKELEEEMTEAITEAAVDSSEEVSEERDDLGPLELHD 60

Query: 61   SGTFQQVVNLLDIIDSESAKTDTTGAGLDMRKTLASVIIMEKATTEPSVVINTLIRCLQV 120
            SGTFQQVVNLLDIIDSESAKTDTTGAGLDMRKTLASVIIMEKATTEPSVVINTLIRCLQV
Sbjct: 61   SGTFQQVVNLLDIIDSESAKTDTTGAGLDMRKTLASVIIMEKATTEPSVVINTLIRCLQV 120

Query: 121  PEISTQRKVNIYNILQDIIQQEGELEEQCVQRLVAIASKEMREIPEMEGYMKAEVASDTL 180
            PEISTQRKVNIYNILQDIIQQEGELEEQCVQRLVAIASKEMREIPEMEGYMKAEVASDTL
Sbjct: 121  PEISTQRKVNIYNILQDIIQQEGELEEQCVQRLVAIASKEMREIPEMEGYMKAEVASDTL 180

Query: 181  VALSRNHFSLVMYELQHHLKPLNLTDEFVIITLAKLANGNVFEFMPYMGITLATIFTMLR 240
            VALSRNHFSLVMYELQHHLKPLNLTDEFVIITLAKLANGNVFEFMPYMGITLATIFTMLR
Sbjct: 181  VALSRNHFSLVMYELQHHLKPLNLTDEFVIITLAKLANGNVFEFMPYMGITLATIFTMLR 240

Query: 241  LANEAKIRQAICSAMETFCETVQFYLKHLEESVYPVMTEEEFALKVFPMYRYFVTVWLRH 300
            LANEAKIRQAICSAMETFCETVQFYLKHLEESVYPVMTEEEFALKVFPMYRYFVTVWLRH
Sbjct: 241  LANEAKIRQAICSAMETFCETVQFYLKHLEESVYPVMTEEEFALKVFPMYRYFVTVWLRH 300

Query: 301  HNPEVKLGVIKSLKPMLGLLLPNDDLREQVYDYIPLLLAEYQGKGHLPPFANPLQVLRQI 360
            HNPEVKLGVIKSLKPMLGLLLPNDDLREQVYDYIPLLLAEYQG           QVLRQI
Sbjct: 301  HNPEVKLGVIKSLKPMLGLLLPNDDLREQVYDYIPLLLAEYQGSLEA---LFVTQVLRQI 357

Query: 361  LGLSVTTNTPVPQMQLHTIFTELHVQVCNKAPAQHQYSSQNLMEMVHCFVALARSYPKEL 420
            LGLSVTTNTPVPQMQLHTIFTELHVQVCNKAPAQHQYSSQNLMEMVHCFVALARSYPKEL
Sbjct: 358  LGLSVTTNTPVPQMQLHTIFTELHVQVCNKAPAQHQYSSQNLMEMVHCFVALARSYPKEL 417

Query: 421  MKFFFSQMETNKEAVRVGTLNLIRAIVSADEPRMSIRAIYLAIRVVKNTISDTRSKVRMA 480
            MKFFFSQMETNKEAVRVGTLNLIRAIVSADEPRMSIRAIYLAIRVVKNTISDTRSKVRMA
Sbjct: 418  MKFFFSQMETNKEAVRVGTLNLIRAIVSADEPRMSIRAIYLAIRVVKNTISDTRSKVRMA 477

Query: 481  ILHIIGQLALCGYQERIKGWGLKYLSVQLTLSTYKLTNRREKFYQRDLEERMVHKVTMDT 540
            ILHIIGQLALCGYQERIKGWGLKYLSVQLTLSTYKLTNRREKFYQRDLEERMVHKVTMDT
Sbjct: 478  ILHIIGQLALCGYQERIKGWGLKYLSVQLTLSTYKLTNRREKFYQRDLEERMVHKVTMDT 537

Query: 541  VKIITSSVSGMTTEFWVRLLCYIMETDYVEALTPICISLTNLAEHQLHGQDVDVSVAGKS 600
            VKIITSSVSGMTTEFWVRLLCYIMETDYVEALTPICISLTNLAEHQLHGQDVDVSVAGKS
Sbjct: 538  VKIITSSVSGMTTEFWVRLLCYIMETDYVEALTPICISLTNLAEHQLHGQDVDVSVAGKS 597

Query: 601  RQVDLPAPQKLLARLLVLMSSPYKGEGRGIAMLNLLRTLSQSIAPSMADMWELEIALLVR 660
            RQVDLPAPQKLLARLLVLMSSPYKGEGRGIAMLNLLRTLSQSIAPSMADMWELEIALLVR
Sbjct: 598  RQVDLPAPQKLLARLLVLMSSPYKGEGRGIAMLNLLRTLSQSIAPSMADMWELEIALLVR 657

Query: 661  YLEEHTEFTWDQKAWEDKLIQFLRNSLKKTRGSSWSLRLSKELNNQIASFDSPSLEKGFL 720
            YLEEHTEFTWDQKAWEDKLIQFLRNSLKKTRGSSWSLRLSKELNNQIASFDSPSLEKGFL
Sbjct: 658  YLEEHTEFTWDQKAWEDKLIQFLRNSLKKTRGSSWSLRLSKELNNQIASFDSPSLEKGFL 717

Query: 721  YRALGFTLATGLEASKVEVLLLELLYKTDYSNDFDSEGVIMCFGLCARGQVKTVLNVLHD 780
            YRALGFTLATGLEASKVEVLLLELLYKTDYSNDFDSEGVIMCFGLCARGQVKTVLNVLHD
Sbjct: 718  YRALGFTLATGLEASKVEVLLLELLYKTDYSNDFDSEGVIMCFGLCARGQVKTVLNVLHD 777

Query: 781  FEERIQESEQSWQISAWRKDHPWRRETVKSALMVMYSCVASYCHPQLLLNLVDSPITAKI 840
            FEERIQESEQSWQISAWRKDHPWRRETVKSALMVMYSCVASYCHPQLLLNLVDSPITAKI
Sbjct: 778  FEERIQESEQSWQISAWRKDHPWRRETVKSALMVMYSCVASYCHPQLLLNLVDSPITAKI 837

Query: 841  IHHYVSSCQDICLKMAFMKSVVQVTKAINNIKDLEDFHFAQKTTLTSIIVAVIKAEPTDN 900
            IHHYVSSCQDICLKMAFMKSVVQVTKAINNIKDLEDFHFAQKTTLTSIIVAVIKAEPTDN
Sbjct: 838  IHHYVSSCQDICLKMAFMKSVVQVTKAINNIKDLEDFHFAQKTTLTSIIVAVIKAEPTDN 897

Query: 901  LVSPVRALAMEALSHLSKLKPFYSTEENSELMDISIHSVISLQLPGEDNESIKTLYANAL 960
            LVSPVRALAMEALSHLSKLKPFYSTEENSELMDISIHSVISLQLPGEDNESIKTLYANAL
Sbjct: 898  LVSPVRALAMEALSHLSKLKPFYSTEENSELMDISIHSVISLQLPGEDNESIKTLYANAL 957

Query: 961  SSLEQLMESLLQRQLDPKGLQEMVQLLEKWILSEKEWEREKAVSLHLYLMRIYVHSTAVC 1020
            SSLEQLMESLLQRQLDPKGLQEMVQLLEKWILSEKEWEREKAVSLHLYLMRIYVHSTAVC
Sbjct: 958  SSLEQLMESLLQRQLDPKGLQEMVQLLEKWILSEKEWEREKAVSLHLYLMRIYVHSTAVC 1017

Query: 1021 IHLKLGQFGTMVGLIAPCTCDAHQRTRMASMNVLSSLLDLHASQTCSLWGPSKQKELEKC 1080
            IHLKLGQFGTMVGLIAPCTCDAHQRTRMASMNVLSSLLDLHASQTCSLWGPSKQKELEKC
Sbjct: 1018 IHLKLGQFGTMVGLIAPCTCDAHQRTRMASMNVLSSLLDLHASQTCSLWGPSKQKELEKC 1077

Query: 1081 KGDLQSTDVEKIFCASSRIAKVVCMEFSCDEVVSLIQKLCENTGAMNLQHDKASVTWIAS 1140
            KGDLQSTDVEKIFCASSRIAKVVCMEFSCDEVVSLIQKLCENTGAMNLQHDKASVTWIA 
Sbjct: 1078 KGDLQSTDVEKIFCASSRIAKVVCMEFSCDEVVSLIQKLCENTGAMNLQHDKASVTWIAF 1137

Query: 1141 FLQMRAKELEDKVAEILSAILVHLPVVDHPEVRRLLIDGILLLAHHHQETILTSLLRQPL 1200
            FLQMRAKELEDKVAEILSAILVHLPVVDHPEVRRLLIDGILLLAHHHQETILTSLLRQPL
Sbjct: 1138 FLQMRAKELEDKVAEILSAILVHLPVVDHPEVRRLLIDGILLLAHHHQETILTSLLRQPL 1197

Query: 1201 PMESHLAEVWLAVSENVPFARTMLHSLMGRLQSRLSPRISATSKADIWRLAAVDPLMTLC 1260
            PMESHLAEVWLAVSENVPFARTMLHSLMGRLQSRLSPRISATSKADIWRLAAVDPLMTLC
Sbjct: 1198 PMESHLAEVWLAVSENVPFARTMLHSLMGRLQSRLSPRISATSKADIWRLAAVDPLMTLC 1257

Query: 1261 TIHLLIQKLDENDKLPDFLPDLIYTLLLQLGSSHRPEAAPPVLKMWKLVHTTPLPEEMNL 1320
            TIHLLIQKLDENDKLPDFLPDLIYTLLLQLGSSHRPEAAPPVLKMWKLVHTTPLPEEMNL
Sbjct: 1258 TIHLLIQKLDENDKLPDFLPDLIYTLLLQLGSSHRPEAAPPVLKMWKLVHTTPLPEEMNL 1317

Query: 1321 QRCSRGRVTIKSMQLLFKRVKSQHLAHTLDEQAVWDLLQDGGTFLEGVSLLARLCMQHVE 1380
            Q     RVTIKSMQLLFKRVKSQHLAHTLDEQAVWDLLQDGGTFLEGVSLLARLCMQHVE
Sbjct: 1318 Q-----RVTIKSMQLLFKRVKSQHLAHTLDEQAVWDLLQDGGTFLEGVSLLARLCMQHVE 1372

Query: 1381 GHRQRLAELVLRGMDSEVLSCRISSTAVCVEFMSGPVLYQEKLLKPAALLLEKGADQEED 1440
            GHRQRLAELVLRGMDSEVLSCRISSTAVCVEFMSGPVLYQEKLLKPAALLLEKGADQEED
Sbjct: 1373 GHRQRLAELVLRGMDSEVLSCRISSTAVCVEFMSGPVLYQEKLLKPAALLLEKGADQEED 1432

Query: 1441 EALRVLSLRALGNMALGAPKKVKQYRKVLLEKCLGPLREPVSNSVTAEGMEALTKILAEL 1500
            EALRVLSLRALGNMALGAPKKVKQYRKVLLEKCLGPLREPVSNSVTAEGMEALTKILAEL
Sbjct: 1433 EALRVLSLRALGNMALGAPKKVKQYRKVLLEKCLGPLREPVSNSVTAEGMEALTKILAEL 1492

Query: 1501 REGDVGSSFDAMSEQCRIFFDNESELLRLKAFILFGKLARVVGMSKKHFFKGEVKKAWIP 1560
            REGDVGSSFDAMSEQCRIFFDNESELLRLKAFILFGKLARVVGMSKKHFFKGEVKKAWIP
Sbjct: 1493 REGDVGSSFDAMSEQCRIFFDNESELLRLKAFILFGKLARVVGMSKKHFFKGEVKKAWIP 1552

Query: 1561 LMLHSQDPCSNAAQACMATMFQCVHFWGWKSLEHPSGPSDTTTDDKMTIFQTTMCSILVR 1620
            LMLHSQDPCSNAAQACMATMFQCVHFWGWKSLEHPSGPSDT TDDKMT+FQTTMCSIL R
Sbjct: 1553 LMLHSQDPCSNAAQACMATMFQCVHFWGWKSLEHPSGPSDTATDDKMTVFQTTMCSILTR 1612

Query: 1621 KPKGEPAHSEKPAVLYRFLLXTMAYVKNNLSRIRIAACNLAGIIMKQMSTHYLKKLDFPA 1680
            K         KPAVLYRFLL TMAYVKNNLSRIRIAACNLAGIIMKQMSTHYLKKLDFPA
Sbjct: 1613 K---------KPAVLYRFLLETMAYVKNNLSRIRIAACNLAGIIMKQMSTHYLKKLDFPA 1663

Query: 1681 LRNSLQELQLDPDPGVRRAALETLTVLDSCSQHGFLASPQGMS 1723
            LRNSLQELQLDPDPGVRRAALETLTVLDSCSQHGFLASPQGMS
Sbjct: 1664 LRNSLQELQLDPDPGVRRAALETLTVLDSCSQHGFLASPQGMS 1706


>gi|239741905 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]
          Length = 1710

 Score = 3289 bits (8529), Expect = 0.0
 Identities = 1689/1727 (97%), Positives = 1692/1727 (97%), Gaps = 21/1727 (1%)

Query: 1    MCIGPRAELFLVVNICLIQKKTLRKELEEEMTEAITEAAVDSSEEVSEERDDLGPLELHD 60
            MCIGPRAELFLVVNICLIQKKTLRKELEEEMTEAITEAAV SSEEVSEERDDLGPLELHD
Sbjct: 1    MCIGPRAELFLVVNICLIQKKTLRKELEEEMTEAITEAAVASSEEVSEERDDLGPLELHD 60

Query: 61   SGTFQQVVNLLDIIDSESAKTDTTGAGLDMRKTLASVIIMEKATTEPSVVINTLIRCLQV 120
            SGTFQQVVNLLDIIDSESAKTDTTGAGLDMRKTLASVIIMEKATTEPSVVINTLIRCLQV
Sbjct: 61   SGTFQQVVNLLDIIDSESAKTDTTGAGLDMRKTLASVIIMEKATTEPSVVINTLIRCLQV 120

Query: 121  PEISTQRKVNIYNILQDIIQQEGELEEQCVQRLVAIASKEMREIPEMEGYMKAEVASDTL 180
            PEISTQRKVNIYNILQDIIQQEGELEEQCVQRLVAIASKEMREIPEMEGYMKAEVASDTL
Sbjct: 121  PEISTQRKVNIYNILQDIIQQEGELEEQCVQRLVAIASKEMREIPEMEGYMKAEVASDTL 180

Query: 181  VALSRNHFSLVMYELQHHLKPLNLTDEFVIITLAKLANGNVFEFMPYMGITLATIFTMLR 240
            VALSRNHFSLVMYELQHHLKPLNLTDEFVIITLAKLANGNVFEFMPYMGITLATIFTMLR
Sbjct: 181  VALSRNHFSLVMYELQHHLKPLNLTDEFVIITLAKLANGNVFEFMPYMGITLATIFTMLR 240

Query: 241  LANEAKIRQAICSAMETFCETVQFYLKHLEESVYPVMTEEEFALKVFPMYRYFVTVWLRH 300
            LANEAKIRQAICSAMETFCETVQFYLKHLEESVYPVMTEEEFALKVFPMYRYFVTVWLRH
Sbjct: 241  LANEAKIRQAICSAMETFCETVQFYLKHLEESVYPVMTEEEFALKVFPMYRYFVTVWLRH 300

Query: 301  HNPEVKLGVIKSLKPMLGLLLPNDDLREQVYDYIPLLLAEYQGKGHLPPFANPLQVLRQI 360
            +NPEVKLGVIKSLKPMLGLLLPNDDLREQVYDYIPLLLAEYQG   +       QVLRQI
Sbjct: 301  YNPEVKLGVIKSLKPMLGLLLPNDDLREQVYDYIPLLLAEYQGSLEV---LFVTQVLRQI 357

Query: 361  LGLSVTTNTPVPQMQLHTIFTELHVQVCNKAPAQHQYSSQNLMEMVHCFVALARSYPKEL 420
            L LSVTTNTPVPQMQLHTIFTELHVQVCNKAPAQHQYSSQNLMEMVHCFVALARSYPKEL
Sbjct: 358  LELSVTTNTPVPQMQLHTIFTELHVQVCNKAPAQHQYSSQNLMEMVHCFVALARSYPKEL 417

Query: 421  MKFFFSQMETNKEAVRVGTLNLIRAIVSADEPRMSIRAIYLAIRVVKNTISDTRSKVRMA 480
            MKFFFSQMETNKEAVRVGTLNLIRAIVSADEPRMSIRAIYLAIRVVKNTISDTRSKVRMA
Sbjct: 418  MKFFFSQMETNKEAVRVGTLNLIRAIVSADEPRMSIRAIYLAIRVVKNTISDTRSKVRMA 477

Query: 481  ILHIIGQLALCGYQERIKGWGLKYLSVQLTLSTYKLTNRREKFYQRDLEERMVHKVTMDT 540
            ILHIIGQLALCGYQERIKGWGLKYLSVQLTLSTYKLTNRREKFYQRDLEERMVHKVTMDT
Sbjct: 478  ILHIIGQLALCGYQERIKGWGLKYLSVQLTLSTYKLTNRREKFYQRDLEERMVHKVTMDT 537

Query: 541  VKIITSSVSGMTTEFWVRLLCYIMETDYVEALTPICISLTNLAEHQLHGQDVDVSVAGKS 600
            VKIITSSVSGMTTEFWVRLLCYIMETDYVEALTPICISLTNLAEHQLHGQDVDVSVAGKS
Sbjct: 538  VKIITSSVSGMTTEFWVRLLCYIMETDYVEALTPICISLTNLAEHQLHGQDVDVSVAGKS 597

Query: 601  RQVDLPAPQKLLARLLVLMSSPYKGEGRGIAMLNLLRTLSQSIAPSMADMWELEIALLVR 660
            RQVDLPAPQKLLARLLVLMSSPYKGEGRGIAMLNLLRTLSQSIAPSMADMWELEIALLVR
Sbjct: 598  RQVDLPAPQKLLARLLVLMSSPYKGEGRGIAMLNLLRTLSQSIAPSMADMWELEIALLVR 657

Query: 661  YLEEHTEFTWDQKAWEDKLIQFLRNSLKKTRGSSWSLRLSKELNNQIASFDSPSLEKGFL 720
            YLEEHTEFTWDQKAWEDKLIQFLRNSLKKTRGSSWSLRLSKELNNQIASFDSPSLEKGFL
Sbjct: 658  YLEEHTEFTWDQKAWEDKLIQFLRNSLKKTRGSSWSLRLSKELNNQIASFDSPSLEKGFL 717

Query: 721  YRALGFTLATGLEASKVEVLLLELLYKTDYSNDFDSEGVIMCFGLCARGQVKTVLNVLHD 780
            YRALGFTLATGLEASKVEVLLLELLYKTDYSNDFDSEGVIMCFGLCARGQVKTVLNVLHD
Sbjct: 718  YRALGFTLATGLEASKVEVLLLELLYKTDYSNDFDSEGVIMCFGLCARGQVKTVLNVLHD 777

Query: 781  FEERIQESEQSWQISAWRKDHPWRRETVKSALMVMYSCVASYCHPQLLLNLVDSPITAKI 840
            FEERIQESEQSWQISAWRKDHPWRRETVKSALMVMYSCVASYCHPQLLLNLVDSPITAKI
Sbjct: 778  FEERIQESEQSWQISAWRKDHPWRRETVKSALMVMYSCVASYCHPQLLLNLVDSPITAKI 837

Query: 841  IHHYVSSCQDICLKMAFMKSVVQVTKAINNIKDLEDFHFAQKTTLTSIIVAVIKAEPTDN 900
            IHHYVSSCQDICLKMAFMKSVVQVTKAINNIKDLEDFHFAQKTTLTSIIVAVIKAEPTDN
Sbjct: 838  IHHYVSSCQDICLKMAFMKSVVQVTKAINNIKDLEDFHFAQKTTLTSIIVAVIKAEPTDN 897

Query: 901  LVSPVRALAMEALSHLSKLKPFYSTEENSELMDISIHSVISLQLPGEDNESIKTLYANAL 960
            LVSPVRALAMEALSHLSKLKPFYSTEENSELMDISIHSVISLQLPGEDNESIKTLYANAL
Sbjct: 898  LVSPVRALAMEALSHLSKLKPFYSTEENSELMDISIHSVISLQLPGEDNESIKTLYANAL 957

Query: 961  SSLEQLMESLLQRQLDPKGLQEMVQLLEKWILSEKEWEREKAVSLHLYLMRIYVHSTAVC 1020
            SSLEQLMESLLQRQLDPKGLQEMVQLLEKWILSEKEWEREKAVSLHLYLM IYVHSTAVC
Sbjct: 958  SSLEQLMESLLQRQLDPKGLQEMVQLLEKWILSEKEWEREKAVSLHLYLMWIYVHSTAVC 1017

Query: 1021 IHLKLGQFGTMVGLIAPCTCDAHQRTRMASMNVLSSLLDLHASQTCSLWGPSKQKELEKC 1080
            IHLKLGQFGTMVGLIAPCTCDAHQRTRMASMNVLSSLLDLHASQTCSLWGPSKQKELEKC
Sbjct: 1018 IHLKLGQFGTMVGLIAPCTCDAHQRTRMASMNVLSSLLDLHASQTCSLWGPSKQKELEKC 1077

Query: 1081 KGDLQSTDVEKIFCASSRIAKVVCMEFSCDEVVSLIQKLCENTGAMNLQHDKASVTWIAS 1140
            KGDLQSTDVEKIFCASSRIAKVVCMEFSCDEVVSLIQKLCENTGAMNLQHDKASVTWIA 
Sbjct: 1078 KGDLQSTDVEKIFCASSRIAKVVCMEFSCDEVVSLIQKLCENTGAMNLQHDKASVTWIAF 1137

Query: 1141 FLQMRAKELEDKVAEILSAILVHLPVVDHPEVRRLLIDGILLLAHHHQETILTSLLRQPL 1200
            FLQMRAKELEDKVAEILSAILVHLPVVDHPEVRRLLIDGILLLAHHHQETILTSLLRQPL
Sbjct: 1138 FLQMRAKELEDKVAEILSAILVHLPVVDHPEVRRLLIDGILLLAHHHQETILTSLLRQPL 1197

Query: 1201 PMESHLAEVWLAVSENVPFARTMLHSLMGRLQSRLSPRISATSKADIWRLAAVDPLMTLC 1260
            PMESHLAEVWLAVSENVPFARTMLHSLMGRLQSRLSPRISATSKADIWRLAAVDPLMTLC
Sbjct: 1198 PMESHLAEVWLAVSENVPFARTMLHSLMGRLQSRLSPRISATSKADIWRLAAVDPLMTLC 1257

Query: 1261 TIHLLIQKLDENDKLPDFLPDLIYTLLLQLGSSHRPEAAPPVLKMWKLVHTTPLPEEMNL 1320
            TIHLLIQKLDENDKLPDFLPDLIYTLLLQLGSSHRPEAAPPVLKMWKLVHTTPLPEEMNL
Sbjct: 1258 TIHLLIQKLDENDKLPDFLPDLIYTLLLQLGSSHRPEAAPPVLKMWKLVHTTPLPEEMNL 1317

Query: 1321 QRCSRGRVTIKSMQLLFKRVKSQHLAHTLDEQAVWDLLQDGGTFLEGVSLLARLCMQHVE 1380
            Q     RVTIKSMQLLFKRVKSQHLAHTLDEQAVWDLLQDGGTFLEGVSLLARLCMQHVE
Sbjct: 1318 Q-----RVTIKSMQLLFKRVKSQHLAHTLDEQAVWDLLQDGGTFLEGVSLLARLCMQHVE 1372

Query: 1381 GHRQRLAELVLRGMDSEVLSCRISSTAVCVE----FMSGPVLYQEKLLKPAALLLEKGAD 1436
            GHRQRLAELVLRGMDSEVLSCRISSTAVCVE    FMSGPVLYQEKLLKPAALLLEKGAD
Sbjct: 1373 GHRQRLAELVLRGMDSEVLSCRISSTAVCVEMRHRFMSGPVLYQEKLLKPAALLLEKGAD 1432

Query: 1437 QEEDEALRVLSLRALGNMALGAPKKVKQYRKVLLEKCLGPLREPVSNSVTAEGMEALTKI 1496
            QEEDEALRVLSLRALGNMALGAPKKVKQYRKVLLEKCLGPLREPVSNSVTAEGMEALTKI
Sbjct: 1433 QEEDEALRVLSLRALGNMALGAPKKVKQYRKVLLEKCLGPLREPVSNSVTAEGMEALTKI 1492

Query: 1497 LAELREGDVGSSFDAMSEQCRIFFDNESELLRLKAFILFGKLARVVGMSKKHFFKGEVKK 1556
            LAELREGDVGSSFDAMSEQCRIFFDNESELLRLKAFILFGKLARVVGMSKKHFFKGEVKK
Sbjct: 1493 LAELREGDVGSSFDAMSEQCRIFFDNESELLRLKAFILFGKLARVVGMSKKHFFKGEVKK 1552

Query: 1557 AWIPLMLHSQDPCSNAAQACMATMFQCVHFWGWKSLEHPSGPSDTTTDDKMTIFQTTMCS 1616
            AWIPLMLHSQDPCSNAAQACMATMFQCVHFWGWKSLEHPSGPSDT TDDKMT+FQTTMCS
Sbjct: 1553 AWIPLMLHSQDPCSNAAQACMATMFQCVHFWGWKSLEHPSGPSDTATDDKMTVFQTTMCS 1612

Query: 1617 ILVRKPKGEPAHSEKPAVLYRFLLXTMAYVKNNLSRIRIAACNLAGIIMKQMSTHYLKKL 1676
            IL RK         KPAVLYRFLL TMAYVKNNLSRIRIAACNLAGIIMKQMSTHYLKKL
Sbjct: 1613 ILTRK---------KPAVLYRFLLETMAYVKNNLSRIRIAACNLAGIIMKQMSTHYLKKL 1663

Query: 1677 DFPALRNSLQELQLDPDPGVRRAALETLTVLDSCSQHGFLASPQGMS 1723
            DFPALRNSLQELQLDPDPGVRRAALETLTVLDSCSQHGFLASPQGMS
Sbjct: 1664 DFPALRNSLQELQLDPDPGVRRAALETLTVLDSCSQHGFLASPQGMS 1710


>gi|154240671 HEAT repeat family member 7B2 [Homo sapiens]
          Length = 1585

 Score =  644 bits (1662), Expect = 0.0
 Identities = 473/1620 (29%), Positives = 813/1620 (50%), Gaps = 104/1620 (6%)

Query: 128  KVNIYNILQDIIQQEGELEEQCVQRLVAIASKEMREIPEMEGYMKAEVASDTLVALSRNH 187
            K +IY+ L  +IQ    L++  VQRL+  ASK+MR+   +       +A + LV+L+ + 
Sbjct: 30   KEDIYSHLTSVIQNTDILDDAIVQRLIYYASKDMRDNNMLREIRM--LAGEVLVSLAAHD 87

Query: 188  FSLVMYELQHHLKPLNLTDEFVIITLAKLANGNVFEFMPYMGITLATIFTMLRLANEAKI 247
            F+ VMYE+Q + + L L DEFV++ LA+LA   V + +P+M +TL T+ TMLRLA + ++
Sbjct: 88   FNSVMYEVQSNFRILELPDEFVVLALAELATSYVSQSIPFMMMTLLTMQTMLRLAEDERM 147

Query: 248  RQAICSAMETFCETVQFYLKHLEESVYPVMTEEEFALKVFPMYRYFVTVWLRHHNPEVKL 307
            +   C A+E F + +  Y+ H  +  YP +     + K+F ++ Y +  W    +P   L
Sbjct: 148  KGTFCIALEKFSKAIYKYVNHWRDFPYPRLDANRLSDKIFMLFWYIMEKWAPLASPMQTL 207

Query: 308  GVIKSLKPMLGLLLPNDDLREQVYDYIPLLLAEYQGKGHLPPFANPLQVLRQILGLSVTT 367
             ++K+  P + LLL  +D R      +P LL +Y+ K       +  Q L+QIL  +V  
Sbjct: 208  SIVKAHGPTVSLLLHREDFRGYALGQVPWLLNQYKDK---EIDFHVTQSLKQILTAAVLY 264

Query: 368  NTPVPQMQLHTIFTELHVQVCNKAPAQHQYSSQNLMEMVHCFVALARSYPKELMKFFFSQ 427
            +  +P+    +IF  L  Q+C    A      +N M+   CF+ LA S P ELM+FF  Q
Sbjct: 265  DIGLPRSLRRSIFINLLQQICR---APEPPVKENEMKASSCFLILAHSNPGELMEFFDEQ 321

Query: 428  METNKEAVRVGTLNLIRAIVSADEPRMSIRAIYLAIRVVKNTISDTRSKVRMAILHIIGQ 487
            + +N EA+RVG L L+R  V+ADEPR+    I +  R VK  + D  +KVR ++L +I  
Sbjct: 322  VRSNNEAIRVGILTLLRLAVNADEPRLRDHIISIE-RTVKIVMGDLSTKVRNSVLLLIQT 380

Query: 488  LALCGYQERIKGWGLKYLSVQLTLSTYKLTNR------REKFYQRDLEERMVHKVTMDTV 541
            +    Y E  +GW L    +    S +   NR      +  F++ + EE  V + +++ +
Sbjct: 381  MCEKSYIEAREGWPL----IDYVFSQFATLNRNLEKPVKTNFHENEKEEESVRETSLEVL 436

Query: 542  KIITSSVSGMTTEFWVRLLCYIMETDYVEALTPI--CISLTNLAEH-QLHGQDVDVSVAG 598
            K +   V GM    W R+L +++  +Y EAL P+   I +  +AE  + H      ++  
Sbjct: 437  KTLDPLVIGMPQVLWPRILTFVVPAEYTEALEPLFSIIRILIMAEEKKQHSAKESTALVV 496

Query: 599  KSRQVDLPAPQKLLARLLVLMSSPYKGEGRGIAMLNLLRTLSQSIAPSMADMWELEIALL 658
             +  V LP+PQ+LLARLLV+      GE RG   + LL+ L + I P + D+W+  +  L
Sbjct: 497  STGAVKLPSPQQLLARLLVISMPASLGELRGAGAIGLLKILPEIIHPKLVDLWKTRLPEL 556

Query: 659  VRYLEEHTEFTWDQKAWEDKLIQFLRNSLKKTRGSSWSLRLSKELNNQIASFDSPSLEKG 718
            ++ LE     T     WE  L+Q L+ SL K    +W+++L+++   Q+ S+ + S EK 
Sbjct: 557  LQPLEGKNIST---VLWETMLLQLLKESLWKISDVAWTIQLTQDFKQQMGSYSNNSTEKK 613

Query: 719  FLYRALGFTLATGLEASKVEVLLLELLYKTDYSNDFDSEGVIMCFGLCARGQVKTVLNVL 778
            FL++ALG TLA   ++  V   + E L   +   D   +G+    G CA   +  VL VL
Sbjct: 614  FLWKALGTTLACCQDSDFVNSQIKEFLTAPNQLGD-QRQGITSILGYCAENHLDIVLKVL 672

Query: 779  HDFEERIQESEQSWQISAWRKDHPWRRETVKSALMVMYSCVASYCHPQLLLNLVDSPITA 838
              F     ++++ + ++  +     ++   K+ +MV+Y  VA +   + LL+ ++  I +
Sbjct: 673  KTF-----QNQEKFFMNRCKSLFSGKKSLTKTDVMVIYGAVALHAPKKQLLSRLNQDIIS 727

Query: 839  KIIHHYVSSCQ---------DICLKMAFMKSVVQVTKAINNIKDLEDFHFAQKTTLTSII 889
            +++  +    Q         D+ L+M+F +S+ ++  A+ + +D + F F+ K  L   +
Sbjct: 728  QVLSLHGQCSQVLGMSVMNKDMDLQMSFTRSITEIGIAVQDAED-QGFQFSYKEMLIGYM 786

Query: 890  VAVIKAEPTDNLVSPVRALAMEALSHLSKLKPFYSTEENSELMDISIHSVISL----QLP 945
            +  I+ EP D+L SP+R  A+ A+ +LSKLKP  S +++  +++ +I  ++ L     L 
Sbjct: 787  LDFIRDEPLDSLASPIRWKALIAIRYLSKLKPQLSLQDHLNILEENIRRLLPLPPLENLK 846

Query: 946  GE-----DNESIKTLYANALSSLEQLMESLLQRQLDPKGLQEMVQLLEKWILSEKEWERE 1000
             E     D E I+ LY  ++ +L +L+++++   ++ +  QEM  LL+ W++S+KEWERE
Sbjct: 847  SEGQTDKDKEHIQFLYERSMDALGKLLKTMMWDNVNAEDCQEMFNLLQMWLVSQKEWERE 906

Query: 1001 KAVSLHLYLMRIYVHSTAVCIHLKLGQFGTMVGLIAPCTCDAHQRTRMASMNVLSSLLDL 1060
            +A  +     ++  +      + K+   G+++GL+AP +CD     R A+    SS + L
Sbjct: 907  RAFQI---TAKVLTNDIEAPENFKI---GSLLGLLAPHSCDTLPTIRQAA---ASSTIGL 957

Query: 1061 HASQTCSLWGPSKQKELEKCKGDLQSTDVEKIFCASSRIAKVVCMEFSCDEVVSLIQKLC 1120
               +   L    + + L+  +  L+S DV+     SS+IAK+V      +E++  ++++ 
Sbjct: 958  FYIKGIHL----EVERLQGLQEGLESDDVQVQIKISSKIAKIVSKFIPNEEILMFLEEML 1013

Query: 1121 ENTGAMNLQHDKASVTWIASFLQMRAKELEDKVAEILSAILVHLPVVDHPEVR-RLLIDG 1179
            +   ++N    KA   W+ + L+ +   LED++ EIL  I  H+PV+   E   + +++ 
Sbjct: 1014 DGLESLNPTCTKACGIWMITVLKQQGAALEDQLLEILGTIYHHMPVLRQKEESFQFILEA 1073

Query: 1180 ILLLAHHHQETILTSLLRQPLPMESHLAEVWLAVSENVPFARTMLHSLMGRLQSRLSPRI 1239
            I  +A  H +T++ +LL++PLP +     +W A++E    +  +L +L+ +L++ L   I
Sbjct: 1074 ISQIASFHMDTVVVNLLQKPLPFDRDTKTLWKALAEKPASSGKLLQALIDKLETELEDDI 1133

Query: 1240 SATSKADIWRLAAVDPLMTLCTIHLLIQKLDENDKLPDFLPDLIYTLLLQLGSSHRPEAA 1299
                       A V+ +   C ++ +I        +    P+L +TLLL+L S    +  
Sbjct: 1134 -----------ARVEAISVACAMYEVISM---GTSVTGLYPEL-FTLLLKLVSCTLGQKM 1178

Query: 1300 PPVLKMWK-LVHTTPLPEEMNL-QRCSRGRVTIKSMQLLFKRVKSQHLAHTLDE-QAVWD 1356
              +   W    H     E+  +   C     T+K +Q    R   + LA   DE   +W 
Sbjct: 1179 --LTCPWSHRRHVMQQGEQQQIPDPCRLSTATLKCLQAQAMR---EGLAKESDEGDNLWT 1233

Query: 1357 LLQDGGTFLEGVSLLARLCMQHVEGHRQRLAELVLRGMDSEVLSCRISSTAVCVEFMSGP 1416
            LL    T   GV  LAR       G    + E +L  + S   + RI+  A   E M  P
Sbjct: 1234 LLSSPSTHHIGVCSLARSMAVWQHGVILDIMEQLLSSLTSSSENYRITGAAFFSELMKEP 1293

Query: 1417 VLYQEKLLKPAALLLEKGADQEEDEALRVLSLRALGNMALGAPKKVKQYRKVLLEKCLGP 1476
            +L++   L+   +L+++ A  + +  LR +++R LGN A GAP KVK++++++LE  +  
Sbjct: 1294 ILWKHGNLRNVLILMDQSA-WDSNATLRQMAIRGLGNTASGAPHKVKKHKQLMLESIIRG 1352

Query: 1477 LREPVSNSVTAEGMEALTKILAELREGDVGSSFDAMSEQCRIFFDNESELLRLKAFILFG 1536
            L       V  E ++AL KIL  L + DV   F  +  Q R FF++E + +RL A  LF 
Sbjct: 1353 LYHLARTEVVCESLKALKKILELLTDRDVSFYFKEIVLQTRTFFEDEQDDVRLTAIFLFE 1412

Query: 1537 KLARVVGMSKKHFFKGEVKKAWIPLMLHSQDPCSNAAQACMATMFQCVHFWGWKSLEHPS 1596
             LA + G   K FF  E+KK+ I  +LH  DP      AC   +  C+ F G   L+   
Sbjct: 1413 DLAPLTGRRWKIFFAEEIKKSLISFLLHLWDPNPKIGVACRDVLMVCIPFLG---LQELY 1469

Query: 1597 GPSDTTTDD---KMTIFQTTMCSILVRKPKGEPAHSEKPAVLYRFLLXTMAYVKNNLSRI 1653
            G  D   D    +   F    C  L +K            +L+     +  +  +    I
Sbjct: 1470 GVLDRLLDQDLPRARDFYRQFCVKLAKK---------NQEILWILHTHSFTFFTSTWEVI 1520

Query: 1654 RIAACNLAGIIMKQMSTHYLKKLDFPALRNSLQELQLDPDPGVRRAALETL-TVLDSCSQ 1712
            R AA  L   ++  +++ Y++ LD   L   LQ L+ DP   V+RAA   L T+L  C +
Sbjct: 1521 RSAAVKLTDAVVLNLTSQYVELLDREQLTTRLQALRQDPCISVQRAAEAALQTLLRRCKE 1580


>gi|150010654 HEAT repeat containing 7A isoform 1 [Homo sapiens]
          Length = 1641

 Score =  596 bits (1537), Expect = e-170
 Identities = 457/1586 (28%), Positives = 755/1586 (47%), Gaps = 55/1586 (3%)

Query: 144  ELEEQCVQRLVAIASKEMREIPEMEGYMKAEVASDTLVALSRNHFSLVMYELQHHLKPLN 203
            EL++     ++ +AS EM +  ++    + + AS  LVA+ R   S VM EL   L P  
Sbjct: 79   ELDKDTASTIILLASSEMTKTKDLVWDWQ-QAASGVLVAVGRQFISKVMEELLRRLHPGT 137

Query: 204  LTDEFVIITLAKLANGNVFEFMPYMGITLATIFTMLRLANEAKIRQAICSAMETFCETVQ 263
            L    V+ TLA L+  N F  +P++   L+++  +L +A +  +R A CSA++ F E   
Sbjct: 138  LPHCAVLHTLASLSVANAFGVVPFLPSVLSSLLPVLGVAKQDTVRVAFCSALQRFSEGAL 197

Query: 264  FYLKHLEESVYPVMTEEEFALKVFPMYRYFVTVWLRHHNPEVKLGVIKSLKPMLGLLLPN 323
             YL +L+ +  P + ++ FA  +F  Y      WL+    +++L V+++L PM   LLP+
Sbjct: 198  EYLANLDRAPDPTVRKDAFATDIFSAYDVLFHQWLQSREAKLRLAVVEALGPM-SHLLPS 256

Query: 324  DDLREQVYDYIPLLLAEYQGKGHLPPFANPLQVLRQILGLSVTTNTPVPQMQLHTIFTEL 383
            + L EQ+   +P +LA Y  K H   F    + L QIL  +V+  +   + QL  +   L
Sbjct: 257  ERLEEQLPKLLPGILALY--KKHAETFYLS-KSLGQILEAAVSVGSRTLETQLDALLAAL 313

Query: 384  HVQVCNKAPAQHQYSSQNLMEMVHCFVALARSYPKELMKFFFSQMETNKEAVRVGTLNLI 443
            H Q+C    +       N  E++ CF  LA S P  L+ F   +++T+ E  RVGTL ++
Sbjct: 314  HSQICVPVESSSPLVMSNQKEVLRCFTVLACSSPDRLLAFLLPRLDTSNERTRVGTLQVV 373

Query: 444  RAIVSADEPRMSIRAIYLAIRVVKNTISDTRSKVRMAILHIIGQLALCGYQERIKGWGLK 503
            R ++++   +M  +  ++ +  ++  + DT SKV+ A++ +I  +A  GY E+  G  + 
Sbjct: 374  RHVINSAAAQMEDKKPFI-LSSMRLPLLDTNSKVKRAVVQVISAMAHHGYLEQPGGEAMI 432

Query: 504  YLSVQLTLSTYKLTNRREKFYQRDLEERMVHKVTMDTVKIITSSVSGMTTEFWVRLLCYI 563
               VQ      +    +     +D +   V  +++ T+ +++++V  M+   W  LL ++
Sbjct: 433  EYIVQQCALPPEQEPEKPGPGSKDPKADSVRAISVRTLYLVSTTVDRMSHVLWPYLLQFL 492

Query: 564  METDYVEALTPICISLTNLAEHQLHGQDVDVSVAGKSRQVDLPAPQKLLARLLVLMSSPY 623
                +  ALTP+C SL +LA+ +      D  +        LP+P  +  RLLV+ SSPY
Sbjct: 493  TPVRFTGALTPLCRSLVHLAQKRQEA-GADAFLIQYDAHASLPSPYAVTGRLLVVSSSPY 551

Query: 624  KGEGRGIAMLNLLRTLSQSIAPSMADMWELEIALLVRYLEEHTEFTWDQKAWEDKLIQFL 683
             G+GRG A L LL  L  +I P +   WE  + LL+ YL+EHTE T  Q+ WE+KL+ FL
Sbjct: 552  LGDGRGAAALRLLSVLHPNIHPLLGQHWETTVPLLLGYLDEHTEETLPQEEWEEKLLMFL 611

Query: 684  RNSLKKTRGSSWSLRLSKELNNQIASFDSPSLEKGFLYRALGFTLATGLEASKVEVLLLE 743
            R++L     ++W  +LS EL  Q+  +D    EK FLY+ +G TL        V   L E
Sbjct: 612  RDTLAIISDNAWICQLSLELCRQLPCYDEAPQEKNFLYKCIGTTLGAASSKEVVRKHLQE 671

Query: 744  LLYKTDYSNDFDSEGVIMCFGLCARGQVKTVLNVLHDFEERIQESEQSWQISAWRKDHPW 803
            LL    Y  + + EG+  CFG+CA   ++  L  L DF  R +   +S  I    KD   
Sbjct: 672  LLETARYQEEAEREGLACCFGICAISHLEDTLAQLEDF-VRSEVFRKSIGILNIFKDRSE 730

Query: 804  RR-ETVKSALMVMYSCVASYCHPQLLLNLVDSPITAKIIHHYVS-------SCQDICLKM 855
               E VKSAL++ Y  VA+    +L+L  V+S I   I  H+ +         +D  LK+
Sbjct: 731  NEVEKVKSALILCYGHVAARAPRELVLAKVESDILRNICQHFSTKVLGIKVETKDPALKL 790

Query: 856  AFMKSVVQVTKAINNIKDLEDFHFAQKTTLTSIIVAVIKAEPTDNLVSPVRALAMEALSH 915
              ++SV  V++AI +      FHF +K  L + ++  I+AEP D+L +P+R  AM   ++
Sbjct: 791  CLVQSVCMVSRAICSSTQAGSFHFTRKAELVAQMMEFIRAEPPDSLRTPIRKKAMLTCTY 850

Query: 916  LSKLKPFYSTEENSELMDISIHSVISL--QLPGEDNESIKTLYANALSSLEQLMESLLQR 973
            L  ++P    +  ++++   +HS+++L  +   ED    K+LY   L +LE L+ SLLQR
Sbjct: 851  LVSVEPALDEQARADVIHGCLHSIMALLPEPKEEDGGCQKSLYLETLHALEDLLTSLLQR 910

Query: 974  QLDPKGLQEMVQLLEKWILSEKEWEREKAVSLHLYLMRIYVHSTAVCIHLKLGQFGTMVG 1033
             + P+GLQ M++ L  WI S +  ER +A+ L   L+R ++    V   +     G ++G
Sbjct: 911  NMTPQGLQIMIEHLSPWIKSPRGHERARALGLSALLLRYFLEHLRVSALVPFHNLGLLIG 970

Query: 1034 LIAPCTCDAHQRTRMASMNVLSSLLDLHASQT--CSLWGPSKQKELEKCKGDLQSTDVEK 1091
            L +P   D    TR  +++ + SLL L          +     + L   K  L   D   
Sbjct: 971  LFSPRCADLWPATRQEAVDCVYSLLYLQLGYEGFSRDYRDDVAERLLSLKDGLVHPDPAI 1030

Query: 1092 IFCASSRIAKVVCMEFSCDEVVSLIQKLCENTGAMNLQHDKASVTWIASFLQMRAKELED 1151
            +F     + +++      D+++SL+  + E  G       +A+   I   LQ R   L++
Sbjct: 1031 LFHTCHSVGQIIAKRLPPDQLISLLLTMFEALGDPEKNCSRAATVMINCLLQERGGVLQE 1090

Query: 1152 KVAEILSAILVHLPVVDHPEVRRLLIDGILLLAHHHQETILTSLLRQPLPMESHLAEVWL 1211
            KV EI+S +   L       V       + LLA  H   +++SLL  PLP++SH   +W 
Sbjct: 1091 KVPEIVSVLRSKLQEAQGEHVLPAAQHSVYLLATQHCAAVVSSLLGSPLPLDSHTCMLWR 1150

Query: 1212 AVSENVPFARTMLHSLMGRLQSRLSPRISATSKADIW-----RLAAVDPLMTLCTIHLLI 1266
            A++     A  +L  L+ ++ SR  P     S+A +      R+A + PL   C +  ++
Sbjct: 1151 ALAVEPRLAAQVLGLLLEKM-SRDVP--FKESRAFLLGRTPDRVATLLPLSATCALFEVM 1207

Query: 1267 QKLDENDKLPDFLPDLIYTLLLQLGSSHRPEAAPPVLKMWKLVHTTPLPEEMNLQRCSRG 1326
                    + +  P L   LLL++  +   +  P  L+  +    +P     NL+ CS  
Sbjct: 1208 STPAAGPAVLELYPQLFVVLLLRVSCTVGVQ-LPRNLQAQERRGASPALATRNLEPCSSA 1266

Query: 1327 RVTIKSMQLLFKRVKSQHLAHTLDEQAVWDLLQDGGTFLEGVSLLARLCMQHVEGHRQRL 1386
              T++SM L   R  S+ +   +D +  W+LL+      EG + LAR   +H       +
Sbjct: 1267 VDTLRSMLL---RSGSEDVVQRMDLEGGWELLRTSAGHEEGATRLARAMAEHAGPRLPLV 1323

Query: 1387 AELVLRGMDSEVLSCRISSTAVCVEFMSGPVLYQEKLLKPAALLLEKGADQEED--EALR 1444
             + +     S   + R+++TA   E ++  V     LL     LLE  A +++D   ++R
Sbjct: 1324 LKTLACTHSSAYENQRVTTTAFLAELLNSNVANDLMLLDS---LLESLAARQKDTCASVR 1380

Query: 1445 VLSLRALGNMALGAPKKVKQYRKVLLEKCLGPLREPVS--NSVTAEGMEALTKILAELRE 1502
             L LR L N+A G P KV+ +   LL   +G L +  +  + V  E M  L +++  +  
Sbjct: 1381 RLVLRGLANLASGCPDKVRTHGPQLLTAMIGGLDDGDNPHSPVALEAMLGLARLVHLVES 1440

Query: 1503 GDVGSSFDAMSEQCRIFFDNESELLRLKAFILFGKLARVVGMSKKHFFKGEVKKAWIPLM 1562
             D+ S    ++ + R FFD+E    R  +  LFG L +V     +  F  +V     PL+
Sbjct: 1441 WDLRSGLLHVAIRIRPFFDSEKMEFRTASIRLFGHLNKVCHGDCEDVFLDQVVGGLAPLL 1500

Query: 1563 LHSQDPCSNAAQACMATMFQCVHFWGWKSLEHPSGPSDTTTDDKMTI----FQTTMCSIL 1618
            LH QDP +  A AC   +  C      + L   S        +   +    F  T C  L
Sbjct: 1501 LHLQDPQATVASACRFALRMCGPNLACEEL---SAAFQKHLQEGRALHFGEFLNTTCKHL 1557

Query: 1619 VRKPKGEPAHSEKPAVLYRFLLXTMAYVKNNLSRIRIAACNLAGIIMKQMSTHYLKKLDF 1678
            +            P +L R L   + Y K++   +R AA    G ++         ++D 
Sbjct: 1558 MH---------HFPDLLGRLLTTCLFYFKSSWENVRAAAPLFTGFLVLHSEPRQQPQVDL 1608

Query: 1679 PALRNSLQELQLDPDPGVRRAALETL 1704
              L  +LQ L  DP P VR  A E L
Sbjct: 1609 DQLIAALQILLKDPAPEVRTRAAEAL 1634


>gi|113420243 PREDICTED: hypothetical protein LOC377711 isoform 5
            [Homo sapiens]
          Length = 1218

 Score =  441 bits (1134), Expect = e-123
 Identities = 347/1204 (28%), Positives = 563/1204 (46%), Gaps = 49/1204 (4%)

Query: 526  RDLEERMVHKVTMDTVKIITSSVSGMTTEFWVRLLCYIMETDYVEALTPICISLTNLAEH 585
            +D +   V  +++ T+ +++++V  M+   W  LL ++    +  ALTP+C SL +LA+ 
Sbjct: 32   KDPKADSVRAISVRTLYLVSTTVDRMSHVLWPYLLQFLTPVRFTGALTPLCRSLVHLAQK 91

Query: 586  QLHGQDVDVSVAGKSRQVDLPAPQKLLARLLVLMSSPYKGEGRGIAMLNLLRTLSQSIAP 645
            +      D  +        LP+P  +  RLLV+ SSPY G+GRG A L LL  L  +I P
Sbjct: 92   RQEA-GADAFLIQYDAHASLPSPYAVTGRLLVVSSSPYLGDGRGAAALRLLSVLHPNIHP 150

Query: 646  SMADMWELEIALLVRYLEEHTEFTWDQKAWEDKLIQFLRNSLKKTRGSSWSLRLSKELNN 705
             +   WE  + LL+ YL+EHTE T  Q+ WE+KL+ FLR++L     ++W  +LS EL  
Sbjct: 151  LLGQHWETTVPLLLGYLDEHTEETLPQEEWEEKLLMFLRDTLAIISDNAWICQLSLELCR 210

Query: 706  QIASFDSPSLEKGFLYRALGFTLATGLEASKVEVLLLELLYKTDYSNDFDSEGVIMCFGL 765
            Q+  +D    EK FLY+ +G TL        V   L ELL    Y  + + EG+  CFG+
Sbjct: 211  QLPCYDEAPQEKNFLYKCIGTTLGAASSKEVVRKHLQELLETARYQEEAEREGLACCFGI 270

Query: 766  CARGQVKTVLNVLHDFEERIQESEQSWQISAWRKDHPWRR-ETVKSALMVMYSCVASYCH 824
            CA   ++  L  L DF  R +   +S  I    KD      E VKSAL++ Y  VA+   
Sbjct: 271  CAISHLEDTLAQLEDF-VRSEVFRKSIGILNIFKDRSENEVEKVKSALILCYGHVAARAP 329

Query: 825  PQLLLNLVDSPITAKIIHHYVS-------SCQDICLKMAFMKSVVQVTKAINNIKDLEDF 877
             +L+L  V+S I   I  H+ +         +D  LK+  ++SV  V++AI +      F
Sbjct: 330  RELVLAKVESDILRNICQHFSTKVLGIKVETKDPALKLCLVQSVCMVSRAICSSTQAGSF 389

Query: 878  HFAQKTTLTSIIVAVIKAEPTDNLVSPVRALAMEALSHLSKLKPFYSTEENSELMDISIH 937
            HF +K  L + ++  I+AEP D+L +P+R  AM   ++L  ++P    +  ++++   +H
Sbjct: 390  HFTRKAELVAQMMEFIRAEPPDSLRTPIRKKAMLTCTYLVSVEPALDEQARADVIHGCLH 449

Query: 938  SVISL--QLPGEDNESIKTLYANALSSLEQLMESLLQRQLDPKGLQEMVQLLEKWILSEK 995
            S+++L  +   ED    K+LY   L +LE L+ SLLQR + P+GLQ M++ L  WI S +
Sbjct: 450  SIMALLPEPKEEDGGCQKSLYLETLHALEDLLTSLLQRNMTPQGLQIMIEHLSPWIKSPR 509

Query: 996  EWEREKAVSLHLYLMRIYVHSTAVCIHLKLGQFGTMVGLIAPCTCDAHQRTRMASMNVLS 1055
              ER +A+ L   L+R ++    V   +     G ++GL +P   D    TR  +++ + 
Sbjct: 510  GHERARALGLSALLLRYFLEHLRVSALVPFHNLGLLIGLFSPRCADLWPATRQEAVDCVY 569

Query: 1056 SLLDLHASQT--CSLWGPSKQKELEKCKGDLQSTDVEKIFCASSRIAKVVCMEFSCDEVV 1113
            SLL L          +     + L   K  L   D   +F     + +++      D+++
Sbjct: 570  SLLYLQLGYEGFSRDYRDDVAERLLSLKDGLVHPDPAILFHTCHSVGQIIAKRLPPDQLI 629

Query: 1114 SLIQKLCENTGAMNLQHDKASVTWIASFLQMRAKELEDKVAEILSAILVHLPVVDHPEVR 1173
            SL+  + E  G       +A+   I   LQ R   L++KV EI+S +   L       V 
Sbjct: 630  SLLLTMFEALGDPEKNCSRAATVMINCLLQERGGVLQEKVPEIVSVLRSKLQEAQGEHVL 689

Query: 1174 RLLIDGILLLAHHHQETILTSLLRQPLPMESHLAEVWLAVSENVPFARTMLHSLMGRLQS 1233
                  + LLA  H   +++SLL  PLP++SH   +W A++     A  +L  L+ ++ S
Sbjct: 690  PAAQHSVYLLATQHCAAVVSSLLGSPLPLDSHTCMLWRALAVEPRLAAQVLGLLLEKM-S 748

Query: 1234 RLSPRISATSKADIW-----RLAAVDPLMTLCTIHLLIQKLDENDKLPDFLPDLIYTLLL 1288
            R  P     S+A +      R+A + PL   C +  ++        + +  P L   LLL
Sbjct: 749  RDVP--FKESRAFLLGRTPDRVATLLPLSATCALFEVMSTPAAGPAVLELYPQLFVVLLL 806

Query: 1289 QLGSSHRPEAAPPVLKMWKLVHTTPLPEEMNLQRCSRGRVTIKSMQLLFKRVKSQHLAHT 1348
            ++  +   +  P  L+  +    +P     NL+ CS    T++SM L   R  S+ +   
Sbjct: 807  RVSCTVGVQ-LPRNLQAQERRGASPALATRNLEPCSSAVDTLRSMLL---RSGSEDVVQR 862

Query: 1349 LDEQAVWDLLQDGGTFLEGVSLLARLCMQHVEGHRQRLAELVLRGMDSEVLSCRISSTAV 1408
            +D +  W+LL+      EG + LAR   +H       + + +     S   + R+++TA 
Sbjct: 863  MDLEGGWELLRTSAGHEEGATRLARAMAEHAGPRLPLVLKTLACTHSSAYENQRVTTTAF 922

Query: 1409 CVEFMSGPVLYQEKLLKPAALLLEKGADQEED--EALRVLSLRALGNMALGAPKKVKQYR 1466
              E ++  V     LL     LLE  A +++D   ++R L LR L N+A G P KV+ + 
Sbjct: 923  LAELLNSNVANDLMLLDS---LLESLAARQKDTCASVRRLVLRGLANLASGCPDKVRTHG 979

Query: 1467 KVLLEKCLGPLREPVS--NSVTAEGMEALTKILAELREGDVGSSFDAMSEQCRIFFDNES 1524
              LL   +G L +  +  + V  E M  L +++  +   D+ S    ++ + R FFD+E 
Sbjct: 980  PQLLTAMIGGLDDGDNPHSPVALEAMLGLARLVHLVESWDLRSGLLHVAIRIRPFFDSEK 1039

Query: 1525 ELLRLKAFILFGKLARVVGMSKKHFFKGEVKKAWIPLMLHSQDPCSNAAQACMATMFQCV 1584
               R  +  LFG L +V     +  F  +V     PL+LH QDP +  A AC   +  C 
Sbjct: 1040 MEFRTASIRLFGHLNKVCHGDCEDVFLDQVVGGLAPLLLHLQDPQATVASACRFALRMCG 1099

Query: 1585 HFWGWKSLEHPSGPSDTTTDDKMTI----FQTTMCSILVRKPKGEPAHSEKPAVLYRFLL 1640
                 + L   S        +   +    F  T C  L+            P +L R L 
Sbjct: 1100 PNLACEEL---SAAFQKHLQEGRALHFGEFLNTTCKHLMH---------HFPDLLGRLLT 1147

Query: 1641 XTMAYVKNNLSRIRIAACNLAGIIMKQMSTHYLKKLDFPALRNSLQELQLDPDPGVRRAA 1700
              + Y K++   +R AA    G ++         ++D   L  +LQ L  DP P VR  A
Sbjct: 1148 TCLFYFKSSWENVRAAAPLFTGFLVLHSEPRQQPQVDLDQLIAALQILLKDPAPEVRTRA 1207

Query: 1701 LETL 1704
             E L
Sbjct: 1208 AEAL 1211


>gi|148727311 hypothetical protein LOC389690 [Homo sapiens]
          Length = 1318

 Score =  202 bits (513), Expect = 3e-51
 Identities = 247/1117 (22%), Positives = 439/1117 (39%), Gaps = 119/1117 (10%)

Query: 671  DQKAWEDKLIQFLRNSLKKTRGSSWSLRLSKELNNQIASFDSPSLEKGFLYRALGFTLAT 730
            D+  WE++LIQ    S+       WS  L   L     +    S EK FL+   G  L  
Sbjct: 240  DKACWEEQLIQMAIKSVPFLSTDVWSKELLWTLTTPSWTQQEQSPEKAFLFTYYGLILQA 299

Query: 731  GLEASKVEVLLLELLYKTDYSNDFDSEGVIMCFGLCARGQVKTVLNVLHDFEERIQESEQ 790
                + V   L  LL +T +      EG+ +  GL A   +  V  VL  F  R +    
Sbjct: 300  EKNGATVRRHLQALL-ETSHQWPKQREGMALTLGLAATRHLDDVWAVLDQFG-RSRPIRW 357

Query: 791  SWQISAWRKDHPWRRETVKSALMVMYSCVASYCHPQLLLNLVDSPITAKIIHHYVSSCQD 850
            S   S+ +     R +   S +++ Y  VA+     +L   VD+ I ++++ ++  S  D
Sbjct: 358  SLPSSSPKNSEDLRWKWASSTILLAYGQVAAKARAHIL-PWVDN-IVSRMVFYFHYSSWD 415

Query: 851  ICLKMAFMKSVVQVTKAINNIKDLEDFHFAQKTTLTSIIVAVIKAEPTDNLVSPVRALAM 910
              LK +F+ + + +  A++  +    + F Q + L   ++ +++ EP D L +  R  AM
Sbjct: 416  ETLKQSFLTATLMLMGAVSRSEGAHSYEFFQTSELLQCLMVLMEKEPQDTLCTRSRQQAM 475

Query: 911  EALSHLSKLKPFYSTEENSELMDISIHSVISLQLPG------------------------ 946
               S L KL+P    E  S+L+     SV +L L                          
Sbjct: 476  HIASSLCKLRPPIDLERKSQLLSTCFRSVFALPLLDALEKHTCLFLEPPNIQLWPVARER 535

Query: 947  --------------EDNESIKTLYANALSSLEQLMESLLQRQLDPKGLQEMVQLLEKWIL 992
                            +E +++LY+  + +L+ +++SL+ +      L  ++  L  W+ 
Sbjct: 536  AGWTHQGWGPRAVLHCSEHLQSLYSRTMEALDFMLQSLIMQNPTADELHFLLSHLYIWLA 595

Query: 993  SEKEWEREKAVSLHLYLMRIYVHSTAVCIHLKLGQFGTMVGLIAPCTCDAHQRTRMASMN 1052
            SEK  ER++AV   + L++   H+  +       + G +VG++     D  + T+  S+ 
Sbjct: 596  SEKAHERQRAVHSCMILLKFLNHNGYLDPKEDFKRIGQLVGILGMLCQDPDRATQRCSLE 655

Query: 1053 VLSSLLDL------------------HASQTCS----LWGPSKQKELEKCKGDLQSTDVE 1090
              S L  L                    SQ  S    LW    QK       ++    + 
Sbjct: 656  GASHLYQLLMCHKTGEALQAESQAPKELSQAHSDGAPLWNSRDQKATPLGPQEMAKNHIF 715

Query: 1091 KIFCASSRIAKVVCMEFSCDEVVSLIQKLCENTGAMNLQHDKASVTWIASFLQMRAKELE 1150
            ++   S ++ K +  + +  E+  LI    +  G+ +    +A+   + + +Q    +LE
Sbjct: 716  QL--CSFQVIKDIMQQLTLAELSDLIWTAIDGLGSTSPFRVQAASEMLLTAVQEHGAKLE 773

Query: 1151 DKVAEILSAILVHLPVVDHPEVRRLLIDGILLLAHHHQETILTSLLRQPLPMESHLAEVW 1210
              V+ +  AI + L  V  P+ +   +  I LLA  H   ++ + L   +P++SH  ++W
Sbjct: 774  I-VSSMAQAIRLRLCSVHIPQAKEKTLHAITLLARSHTCELVATFLNISIPLDSHTFQLW 832

Query: 1211 LAVSENVPFARTMLHSLMGRLQSRLSPRISATSKADIWRLAAVDPLMTLCTIHLLIQKLD 1270
             A+    P +  +L +L+  LQ R  P  ++ S         +  L  +  +H L    +
Sbjct: 833  RALGAGQPTSHLVLTTLLACLQERPLPTGASDSSPCPKEKTYLRLLAAMNMLHELQFARE 892

Query: 1271 ENDKLPDFLPDLIYTLLLQLG---SSHRPEAAPPVLKMWKLVHTTPLPEEMNLQRCSRGR 1327
                + +  P L   LL Q+      + P    P  +  +    +P       Q CS   
Sbjct: 893  FKQAVQEGYPKLFLALLTQMHYVLELNLPSEPQPKQQAQEAAVPSP-------QSCSTSL 945

Query: 1328 VTIKSMQLLFKRVKSQHLAHTLDEQAVWDLLQDGGTFLEGVSLLARLCMQHVEGHRQRLA 1387
              +KS  LL         AH L+ Q  W+L     T+ +GV LLAR  +Q+       + 
Sbjct: 946  EALKS--LLSTTGHWHDFAH-LELQGSWELFTTIHTYPKGVGLLARAMVQNHCRQIPAVL 1002

Query: 1388 ELVLRGMDSEVLSCRISSTAVCVEFMSGPVLYQEKLLKPAALLLEKGADQEEDEALRVLS 1447
              +L  + S     R  +  +  +F+  PVL  E L K AAL +      +    +RVLS
Sbjct: 1003 RQLLPSLQSPQERERKVAILILTKFLYSPVLL-EVLPKQAALTVLAQGLHDPSPEVRVLS 1061

Query: 1448 LRALGNMALGAPKKVKQYRKVLLEKCLGPLREPV---SNSVTAEGMEALTKILAELREGD 1504
            L+ L N+     K        LL+  L PL +     S+ V    M  ++  L  L    
Sbjct: 1062 LQGLSNILFHPDKGS------LLQGQLRPLLDGFFQSSDQVIVCIMGTVSDTLHRLGAQG 1115

Query: 1505 VGSSFDAMSEQCRIFFDNESELLRLKAFILFGKLARVVGMSKKHFFKGEVKKAWIPLMLH 1564
             GS    ++   R FF++E + +R  A  LFG L   +   +    + +V ++ +PL+LH
Sbjct: 1116 TGSQSLGVAISTRSFFNDERDGIRAAAMALFGDLVAAMADRELSGLRTQVHQSMVPLLLH 1175

Query: 1565 SQDPCSNAAQACMATMFQCVHFWGWKSLEHPSGPSDTTTDDKMTIFQTTMCSILVRKPKG 1624
             +D C   A     T ++C     W+                  +  T  C++   +   
Sbjct: 1176 LKDQCPAVATQAKFTFYRCAVLLRWR------------------LLHTLFCTLAWERGL- 1216

Query: 1625 EPAHSEKPAVLYRFLLXTMAYVKNNLSRIRIAACNLAGIIM----------KQMSTHYLK 1674
               H     ++ R       ++   LS +   +C++   +            Q     L 
Sbjct: 1217 SARHFLWTCLMTRSQEEFSIHLSQALSYLHSHSCHIKTWVTLFIGHTICYHPQAVFQMLN 1276

Query: 1675 KLDFPALRNSLQELQLDPDPGVRRAALETLTVLDSCS 1711
             +D   L  + + L+ DP+P +R  A   L+ L   S
Sbjct: 1277 AVDTNLLFRTFEHLRSDPEPSIREFATSQLSFLQKVS 1313



 Score = 38.9 bits (89), Expect = 0.044
 Identities = 28/102 (27%), Positives = 51/102 (50%), Gaps = 2/102 (1%)

Query: 99  IMEKATTEPSVVINTLIRC-LQVPEISTQRKVNIYNILQDIIQQEGELEEQCVQRLVAIA 157
           I   A   P +V+ T+    +  PEIS++ K  ++  L+ +I     LEE   +    +A
Sbjct: 112 IKNMAHGSPKLVMETIHDYFIDNPEISSRHKFRLFQTLEMVIGASDVLEETWEKTFTRLA 171

Query: 158 SKEMREIPEMEGYMKAEVASDTLVALSRNHFSLVMYELQHHL 199
            + M +  E+E   + + AS+ LVA+ R+ + +V   L+  L
Sbjct: 172 LENMTKATELEDIYQ-DAASNMLVAICRHSWRVVAQHLETEL 212


>gi|223278410 hypothetical protein LOC374977 [Homo sapiens]
          Length = 1323

 Score =  167 bits (423), Expect = 8e-41
 Identities = 202/910 (22%), Positives = 391/910 (42%), Gaps = 101/910 (11%)

Query: 855  MAFMKSVVQVTKAINNIKDLEDFHFAQKTTLTSIIVAVIKAEPTDNLVSPVRALAMEALS 914
            MA +++V  + K+    +DL +    +K T+   I+  I+ EP D+L S VR  AME L+
Sbjct: 433  MALVENVTTLQKS----QDLLEAE-GEKKTMIKKIMRQIQEEPLDSLSSSVRKQAMEILT 487

Query: 915  HLSKLKPFYSTEENSELMDISIHSVISL---QLPGEDN----ESIKTLYANALSSLEQLM 967
             LS  +P     E SEL+++ +HSV SL   Q   E +    E+I+ LY   L +L+ L+
Sbjct: 488  QLSHTQPTLGMRERSELVNVCVHSVFSLPSVQAMQEKDEAKAETIQALYHQTLEALQTLL 547

Query: 968  ESLLQRQLDPKGLQEMVQLLEKWILSEKEWEREKAVSLHLYLMRIYVHSTAVCIHLKLGQ 1027
            ++L      P GL+ +++ L  W+ S K  ER +AV+ ++ ++   + +    + L    
Sbjct: 548  KALFIEDPTPAGLKSILEALGPWMNSGKAHERARAVNTNVSVLNHMLLTLPFFMPLGFPA 607

Query: 1028 FGTMVGLIAPCTCDAHQRTRMASMNVLSSLLDLHASQTCSLWGPSKQKELEKCKGDLQST 1087
             G ++G +     D  +     +++ +  L  +               EL+K   D + T
Sbjct: 608  LGLLLGRLILHIGDPDEEIGCEALDGIIILYTI--------------LELQKRARDKEET 653

Query: 1088 DVEKIFCASSRIAKVVCMEFSCDEVVSLIQKLCENTGAMNLQH----------------- 1130
            + ++++ ++            C  ++ +I++  +  G   ++                  
Sbjct: 654  NKKELYESNKHFLGPYNPVSPCQNILRVIEEFGDFLGPQQIKDLLLAALEGLKGSSEAPG 713

Query: 1131 -------DKASVTWIASFLQMRAKELEDKVAEILSAILVHLPVVDHPEVRRLLIDGILLL 1183
                     AS   ++S L+       + + EI+  I + L  +  P  R++ +  + LL
Sbjct: 714  KDSREMMQLASEVMLSSVLEWYRHRALEVIPEIMQGIYMQLSHIQEPRARQVALLPVSLL 773

Query: 1184 AHHHQETILTSLLRQPLPMESHLAEVW--LAVSENVPFARTMLHSLMGRLQSRLSPRISA 1241
            A      ++ +LL  PLP+ S+ AE+W  L + +     R +L  L+G L+ +    ++ 
Sbjct: 774  ASSFMTEVVVALLMCPLPLNSNGAEMWRQLILCKPSCDVRDLLDLLLGSLKEK---PVTK 830

Query: 1242 TSKADIWRLAAVDPLMTLCTIHLLIQKLDENDKLPDFLPDLIYTLLLQLG---SSHRPEA 1298
              +A I  LAA   L  L +++  + ++          P L+  LL+Q+      + P  
Sbjct: 831  EGRASIVPLAAASGLCELLSVNSCMGRVRR------IYPQLLLALLIQVHYHIGLNLPGC 884

Query: 1299 APPVLKMWKLVHTTPLPEEMNLQRCSRGRVTIKSMQLLFKRVKSQHLAHTLDEQAVWDLL 1358
              P     K    +P             R  +K ++ L  R+   +    L++Q  W+L+
Sbjct: 885  VAPPKDTKKGAQPSPFVPV---------RWVVKVVKTLLLRMGCSYETTFLEDQGGWELM 935

Query: 1359 QDGGTFLEGVSLLARLCMQHVEGHRQRLAELVLRGMDSEVLSCRISSTAVCVEFMSGPVL 1418
            +   +   GV+LLAR  +Q+      R+  L++  ++      RI++TA  VE     +L
Sbjct: 936  EQVESHHRGVALLARAMVQYSCQELCRILYLLIPLLERGDEKHRITATAFFVE-----LL 990

Query: 1419 YQEKLLK-PAALLLEKGAD--QEEDEALRVLSLRALGNMALGAPKKVKQYRKVLLEKCLG 1475
              E++ + P    L + A+     D  ++VLS+R L  +A  + K  K   K LL   + 
Sbjct: 991  QMEQVRRIPEEYSLGRMAEGLSHHDPIMKVLSIRGLVILARRSEKTAKV--KALLPSMVK 1048

Query: 1476 PLREPVSNSVTAEGMEALTKILAELREGDVGSS-FDAMSEQCRIFFDNESELLRLKAFIL 1534
             L+  +   +  E +  L  +     +  + S+ +  M +     F +  E++R     L
Sbjct: 1049 GLKN-MDGMLVVEAVHNLKAVFKGRDQKLMDSAVYVEMLQILLPHFSDAREVVRSSCINL 1107

Query: 1535 FGKLARVVGMSKKHFFKGEVKKAWIPLMLHSQDPCSNAAQACMATMFQCVHFWGWKSLEH 1594
            +GK+ + +   +    + ++    +PL+L  Q+  S  +Q C+ T+ +C +F  W   E 
Sbjct: 1108 YGKVVQKLRAPRTQAMEEQLVSTLVPLLLTMQEGNSKVSQKCVKTLLRCSYFMAW---EL 1164

Query: 1595 PSGPSDTTTDDKMTIFQTTMCSILVRKPKGEPAHSEKPAVLYRFLLXTMAYVKNNLSRIR 1654
            P         D        +C  LV        H +   +   FL  ++ Y KN+ + +R
Sbjct: 1165 PKRAYSRKPWDNQQQTVAKICKCLVN------THRDSAFI---FLSQSLEYAKNSRASLR 1215

Query: 1655 IAACNLAGIIMKQMSTHYLKKLDFPALRNSLQELQLDPDPGVRRAALETLT-VLDSCSQH 1713
              +    G ++  M +  + +     ++ +L  L+ DP+  V   A +    +L SC Q+
Sbjct: 1216 KCSVMFIGSLVPCMES-IMTEDRLNEVKAALDNLRHDPEASVCIYAAQVQDHILASCWQN 1274

Query: 1714 GFLASPQGMS 1723
             +L  P G S
Sbjct: 1275 SWL--PHGNS 1282


>gi|194595501 hypothetical protein LOC140699 isoform 1 [Homo sapiens]
          Length = 1052

 Score =  154 bits (389), Expect = 7e-37
 Identities = 194/913 (21%), Positives = 377/913 (41%), Gaps = 88/913 (9%)

Query: 835  PITAKIIHHYVSSCQDI--------CLKMAFMKSVVQVTKAINNIKDLEDFHFAQKTTLT 886
            P++  I+   + S Q +          K+ F+  +  +++A+   +  + F  +    + 
Sbjct: 163  PLSEAIVEKLIQSIQKVFNGELKGELEKLKFLGDLSSLSQALPYDETAKSFIHSHIADIV 222

Query: 887  SIIVAVIKAEPTDNLVSPVRALAMEALSHLS--KLKPFYSTEENSELMDISIHSVISL-- 942
              +  +++ E   +L S +R      ++ LS   +     +E+ +EL  ++I S+I+L  
Sbjct: 223  HTLNVLVQEERPHSLSSSMRQEVFVTIADLSYQDVHLLLGSEDRAELFSLTIKSIITLPS 282

Query: 943  --------QLPGEDNESIKTLYANALSSLEQLMESLLQRQLDPKGLQEMVQLLEKWILSE 994
                    ++      + + LY     +  ++++SL+ +    + L  +++ L  W+ S 
Sbjct: 283  VRTLTQIQEIMPNGTCNTECLYRQTFQAFSEMLQSLVVKDPHLENLDTIIKHLVPWLQSV 342

Query: 995  KEWEREKAVSLHLYLMRIYVHSTAVCIHLKLGQFGTMVGLIAPCTCDAHQRTRMASMNVL 1054
            K+ ERE+A +    +++       + + L+  + G +V L+A    D  ++    +   +
Sbjct: 343  KDHERERATASMAQVLKCLSKHLNLKLPLRFQRLGHLVALMALLCGDPQEKVAEEAAEGI 402

Query: 1055 SSLLDLHASQTCSLWGPSKQKELE----KCKG--DLQSTDVEKIFCASSRIAKVVCMEFS 1108
             SLL +             Q+ L+    KC+   +L S+  +  +    RIA+V      
Sbjct: 403  HSLLHITLRLKYITHDKKDQQNLKRALTKCREFLELHSSAAKCFYNCPFRIAQVFEGFLD 462

Query: 1109 CDEVVSLIQKLCENTGAMNLQHDKASVTWIASFLQMRAKELEDKVAEILSAILVHLPVVD 1168
             +E+   I    +    +     + S   +   L    +   +KV EI+  I   L ++ 
Sbjct: 463  SNELCQFIMTTFDTLKTLKHPCIQRSAGELLLTLAKNTESQFEKVPEIMGVICAQLSIIS 522

Query: 1169 HPEVRRLLIDGILLLAHH--HQETILTSLLRQPLPMESHLAEVWLAVSENVPFARTMLHS 1226
             P VR+ +I+ + L      + + +L+ LL  P+P   HLAEVW  +S  +P    +L  
Sbjct: 523  QPRVRQQIINTVSLFISRPKYTDIVLSFLLCHPVPYNRHLAEVWRMLSVELPSTTWILWR 582

Query: 1227 LMGRLQSRLSPRISATSKADIWRLAAVDPLMTLCTIHLLIQKLDENDKLPDFLPDLIYTL 1286
            L+ +LQ        A  K     +AA D L  +   + L              P L+ TL
Sbjct: 583  LLRKLQK--CHNEPAQEKMAYVAVAATDALYEVFLGNRLRAATFR------LFPQLLMTL 634

Query: 1287 LLQLGSSHRPEAAPPVLKMWKLVHTTPLPEEMNLQRCSRGRVT-----IKSMQLLFKRVK 1341
            L+Q+  S           +   +    +P  +  ++     VT     +++ + L  R  
Sbjct: 635  LIQIHHS-----------IGLTMSDVDIPSGLYTEQEVPSEVTPLCFAMQATKTLLLRTC 683

Query: 1342 SQHLAHTLDEQAVWDLLQDGGTFLEGVSLLARLCMQHVEGHRQR----LAELVLRGMDSE 1397
                 + +++   W LL      L+G+ LLA   ++  +   Q+    L  L+ RG D  
Sbjct: 684  CLQEFNIMEKNKGWALLGGKDGHLQGLFLLANALLERNQLLAQKVMYLLVPLLNRGNDKH 743

Query: 1398 VLSCRISSTAVCVEFMSGPVLYQEKLLKPAALLLEKGADQEEDEALRVLSLRALGNMALG 1457
                +++S    VE +  PV   ++L    ++   K   Q+ +   R+L LR L N+   
Sbjct: 744  ----KLTSAGFFVELLRSPV--AKRLPSIYSVARFKDWLQDGNHLFRILGLRGLYNLV-- 795

Query: 1458 APKKVKQYRKVLLEKCLGPLREPVSNSVTAEGMEALTKILAELREGDVGSSFDAMSEQCR 1517
              +++++  K LL   +  LRE     V    + A+  +L  +R  D  +    M     
Sbjct: 796  GHQEMREDIKSLLPYIVDSLRETDEKIV----LSAIQILLQLVRTMDFTTLAAMMRTLFS 851

Query: 1518 IFFDNESELLRLKAFILFGKLARVVGMSKKHFFKGEVKKAWIPLMLHSQDPCSNAAQACM 1577
            +F D  S++ R  +  LFG   + V    K   + +V  + +PL+L+SQD     A+   
Sbjct: 852  LFGDVRSDVHRF-SVTLFGAAIKSVKNPDKKSIENQVLDSLVPLLLYSQDENDAVAEESR 910

Query: 1578 ATMFQCVHFWGWKSLEHPSGPSDTTTDDKMTIFQT---TMCSILVRKPKGEPAHSEKPAV 1634
              +  C  F  WK       P +  + D   I  T   T+C    +K KG+         
Sbjct: 911  QVLTICAQFLKWKL------PQEVYSKDPWHIKPTEAGTICRFFEKKCKGK--------- 955

Query: 1635 LYRFLLXTMAYVKNNLSRIRIAACNLAGIIMKQMSTHYLKKLDFPALRNSLQELQLDPDP 1694
                L  T+ Y KN    IR +A    G++ K M  + L+++    + + L++L  DP+P
Sbjct: 956  -INILEQTLMYSKNPKLPIRRSAVLFVGLLSKYMDHNELRRMGTDWIEDDLRDLLCDPEP 1014

Query: 1695 GVRRAALETLTVL 1707
             +   A +TL ++
Sbjct: 1015 SLCIIASQTLLLV 1027


>gi|149944578 HEAT repeat containing 7A isoform 2 [Homo sapiens]
          Length = 422

 Score =  150 bits (380), Expect = 8e-36
 Identities = 95/306 (31%), Positives = 160/306 (52%), Gaps = 5/306 (1%)

Query: 144 ELEEQCVQRLVAIASKEMREIPEMEGYMKAEVASDTLVALSRNHFSLVMYELQHHLKPLN 203
           EL++     ++ +AS EM +  ++    + + AS  LVA+ R   S VM EL   L P  
Sbjct: 79  ELDKDTASTIILLASSEMTKTKDLVWDWQ-QAASGVLVAVGRQFISKVMEELLRRLHPGT 137

Query: 204 LTDEFVIITLAKLANGNVFEFMPYMGITLATIFTMLRLANEAKIRQAICSAMETFCETVQ 263
           L    V+ TLA L+  N F  +P++   L+++  +L +A +  +R A CSA++ F E   
Sbjct: 138 LPHCAVLHTLASLSVANAFGVVPFLPSVLSSLLPVLGVAKQDTVRVAFCSALQRFSEGAL 197

Query: 264 FYLKHLEESVYPVMTEEEFALKVFPMYRYFVTVWLRHHNPEVKLGVIKSLKPMLGLLLPN 323
            YL +L+ +  P + ++ FA  +F  Y      WL+    +++L V+++L PM   LLP+
Sbjct: 198 EYLANLDRAPDPTVRKDAFATDIFSAYDVLFHQWLQSREAKLRLAVVEALGPM-SHLLPS 256

Query: 324 DDLREQVYDYIPLLLAEYQGKGHLPPFANPLQVLRQILGLSVTTNTPVPQMQLHTIFTEL 383
           + L EQ+   +P +LA Y  K H   F    + L QIL  +V+  +   + QL  +   L
Sbjct: 257 ERLEEQLPKLLPGILALY--KKHAETFYLS-KSLGQILEAAVSVGSRTLETQLDALLAAL 313

Query: 384 HVQVCNKAPAQHQYSSQNLMEMVHCFVALARSYPKELMKFFFSQMETNKEAVRVGTLNLI 443
           H Q+C    +       N  E++ CF  LA S P  L+ F   +++T+ E  RVGTL ++
Sbjct: 314 HSQICVPVESSSPLVMSNQKEVLRCFTVLACSSPDRLLAFLLPRLDTSNERTRVGTLQVV 373

Query: 444 RAIVSA 449
           R ++++
Sbjct: 374 RHVINS 379


>gi|149944469 HEAT repeat containing 7A isoform 2 [Homo sapiens]
          Length = 422

 Score =  150 bits (380), Expect = 8e-36
 Identities = 95/306 (31%), Positives = 160/306 (52%), Gaps = 5/306 (1%)

Query: 144 ELEEQCVQRLVAIASKEMREIPEMEGYMKAEVASDTLVALSRNHFSLVMYELQHHLKPLN 203
           EL++     ++ +AS EM +  ++    + + AS  LVA+ R   S VM EL   L P  
Sbjct: 79  ELDKDTASTIILLASSEMTKTKDLVWDWQ-QAASGVLVAVGRQFISKVMEELLRRLHPGT 137

Query: 204 LTDEFVIITLAKLANGNVFEFMPYMGITLATIFTMLRLANEAKIRQAICSAMETFCETVQ 263
           L    V+ TLA L+  N F  +P++   L+++  +L +A +  +R A CSA++ F E   
Sbjct: 138 LPHCAVLHTLASLSVANAFGVVPFLPSVLSSLLPVLGVAKQDTVRVAFCSALQRFSEGAL 197

Query: 264 FYLKHLEESVYPVMTEEEFALKVFPMYRYFVTVWLRHHNPEVKLGVIKSLKPMLGLLLPN 323
            YL +L+ +  P + ++ FA  +F  Y      WL+    +++L V+++L PM   LLP+
Sbjct: 198 EYLANLDRAPDPTVRKDAFATDIFSAYDVLFHQWLQSREAKLRLAVVEALGPM-SHLLPS 256

Query: 324 DDLREQVYDYIPLLLAEYQGKGHLPPFANPLQVLRQILGLSVTTNTPVPQMQLHTIFTEL 383
           + L EQ+   +P +LA Y  K H   F    + L QIL  +V+  +   + QL  +   L
Sbjct: 257 ERLEEQLPKLLPGILALY--KKHAETFYLS-KSLGQILEAAVSVGSRTLETQLDALLAAL 313

Query: 384 HVQVCNKAPAQHQYSSQNLMEMVHCFVALARSYPKELMKFFFSQMETNKEAVRVGTLNLI 443
           H Q+C    +       N  E++ CF  LA S P  L+ F   +++T+ E  RVGTL ++
Sbjct: 314 HSQICVPVESSSPLVMSNQKEVLRCFTVLACSSPDRLLAFLLPRLDTSNERTRVGTLQVV 373

Query: 444 RAIVSA 449
           R ++++
Sbjct: 374 RHVINS 379


>gi|154937380 hypothetical protein LOC642475 [Homo sapiens]
          Length = 719

 Score =  116 bits (291), Expect = 2e-25
 Identities = 141/577 (24%), Positives = 243/577 (42%), Gaps = 52/577 (9%)

Query: 1132 KASVTWIASFLQMRAKELEDKVAEILSAILVHLPVVDHPEVRRLLIDGILLLAHHHQETI 1191
            +A+V  ++S L+ R + LED+V  ++  +L  +P +      R  +  +  LA  H   +
Sbjct: 129  QATVLTLSSALEARGERLEDQVHALVRGLLAQVPSLAEGRPWRAALRVLSALALEHARDV 188

Query: 1192 LTSLLRQPLPMESHLAEVWLAVSENVPFARTMLHSLMGRLQSRLSPRISATSKADIWRLA 1251
            + +LL + LP +   AE+W ++S N      +L  L+  L+    P   A        LA
Sbjct: 189  VCALLPRSLPADRVAAELWRSLSRNQRVNGQVLVQLLWALKGASGPEPQA--------LA 240

Query: 1252 AVDPLMTLCTIHLLIQKLDENDKLPDFLPDLIYTLLLQLGSSHRPEAAPPVLKMWKLVHT 1311
            A   L  +  +   +           F P L+  L+ QL    R   +P + K+W L H 
Sbjct: 241  ATRALGEMLAVSGCV------GATRGFYPHLLLALVTQLHKLARSPCSPDMPKIWVLSHR 294

Query: 1312 TPLPEEMNLQRCSRGRVTIKSMQLLFKRVKSQHLAHTLDEQAVWDLLQDGGTFLEGVSLL 1371
             P P        S     +++++ L      + +   +++   W  L    T LEGV LL
Sbjct: 295  GP-PH-------SHASCAVEALKALLTGDGGRMVVTCMEQAGGWRRLVGAHTHLEGVLLL 346

Query: 1372 ARLCMQHVEGHRQRL-AELVLR---GMDSEVLSCRISSTAVCVEFMSGPVLYQEKLLKPA 1427
            A   + H + H + L A+L+ R     D + L+     T +     +  +L +E +L+  
Sbjct: 347  ASAMVAHADHHLRGLFADLLPRLRSADDPQRLTAMAFFTGLLQSRPTARLLREEVILE-- 404

Query: 1428 ALLLEKGADQEEDEALRVLSLRALGNMALGAPKKVKQYRKVLLEKCLGPLREPVSNSVTA 1487
             LL  +G   + +  +R L L  LG++AL   K   ++   LL   LG L E  +  V A
Sbjct: 405  RLLTWQG---DPEPTVRWLGLLGLGHLALNRRKV--RHVSTLLPALLGALGEGDARLVGA 459

Query: 1488 EGMEALTKILAELREGDVGSSFDAMSEQCRIFFDNESELLRLKAFILFGKLARVVGMSKK 1547
              + AL ++L   R   V      +  +     D+  + +R  A  L G L R      +
Sbjct: 460  -ALGALRRLLLRPR-APVRLLSAELGPRLPPLLDDTRDSIRASAVGLLGTLVRRGRGGLR 517

Query: 1548 HFFKGEVKK----AWIPLMLHSQDPCSNAAQACMATMFQCVHFWGWKSLEHPSGPSDTTT 1603
               +G ++K    + +PL+L   DP  +AA++   T+ +C H + W  LE     +   +
Sbjct: 518  LGLRGPLRKLVLQSLVPLLLRLHDPSRDAAESSEWTLARCDHAFCWGLLEELVTVAHYDS 577

Query: 1604 DDKMTIFQTTMCSILVRKPKGEPAHSEKPAVLYRFLLXTMAYVKNNLSRIRIAACNLAGI 1663
             + ++      C ++ R P   P           FL  T  Y+++    +R AA  L G 
Sbjct: 578  PEALSHL---CCRLVQRYPGHVP----------NFLSQTQGYLRSPQDPLRRAAAVLIGF 624

Query: 1664 IMKQMSTHYLKKLDFPALRNSLQELQLDPDPGVRRAA 1700
            ++   S   + +    +L   L  LQ DP P V  AA
Sbjct: 625  LVHHASPGCVNQDLLDSLFQDLGRLQSDPKPAVAAAA 661


>gi|187761381 maestro isoform d [Homo sapiens]
          Length = 262

 Score =  100 bits (248), Expect = 2e-20
 Identities = 58/164 (35%), Positives = 92/164 (56%), Gaps = 2/164 (1%)

Query: 1420 QEKLLKPAALLLEKGADQEEDEALRVLSLRALGNMALGAPKKVKQYRKVLLEKCLGPLRE 1479
            +E L     +L E+  D    +  R +++R LG MA  AP KV++Y+K++L+  +  L +
Sbjct: 57   REPLKNVFFILAERARDPSAKK--RHMAMRNLGTMAYEAPDKVRKYKKIVLDLLVYGLYD 114

Query: 1480 PVSNSVTAEGMEALTKILAELREGDVGSSFDAMSEQCRIFFDNESELLRLKAFILFGKLA 1539
            PV+  V  E M+ LT +L +++   +GS F  ++ Q R   D+E++ LR  AF+LFG+LA
Sbjct: 115  PVNLEVIHESMKTLTVVLGKIQGKGLGSFFIDITLQTRTLLDDENDSLRYSAFVLFGQLA 174

Query: 1540 RVVGMSKKHFFKGEVKKAWIPLMLHSQDPCSNAAQACMATMFQC 1583
               G   K FF  +VK+    L++H QD     A+AC  T   C
Sbjct: 175  AFAGRKWKKFFTSQVKQTRDSLLIHLQDRNPQVAKACKTTFQAC 218


>gi|187761375 maestro isoform a [Homo sapiens]
          Length = 248

 Score =  100 bits (248), Expect = 2e-20
 Identities = 58/164 (35%), Positives = 92/164 (56%), Gaps = 2/164 (1%)

Query: 1420 QEKLLKPAALLLEKGADQEEDEALRVLSLRALGNMALGAPKKVKQYRKVLLEKCLGPLRE 1479
            +E L     +L E+  D    +  R +++R LG MA  AP KV++Y+K++L+  +  L +
Sbjct: 43   REPLKNVFFILAERARDPSAKK--RHMAMRNLGTMAYEAPDKVRKYKKIVLDLLVYGLYD 100

Query: 1480 PVSNSVTAEGMEALTKILAELREGDVGSSFDAMSEQCRIFFDNESELLRLKAFILFGKLA 1539
            PV+  V  E M+ LT +L +++   +GS F  ++ Q R   D+E++ LR  AF+LFG+LA
Sbjct: 101  PVNLEVIHESMKTLTVVLGKIQGKGLGSFFIDITLQTRTLLDDENDSLRYSAFVLFGQLA 160

Query: 1540 RVVGMSKKHFFKGEVKKAWIPLMLHSQDPCSNAAQACMATMFQC 1583
               G   K FF  +VK+    L++H QD     A+AC  T   C
Sbjct: 161  AFAGRKWKKFFTSQVKQTRDSLLIHLQDRNPQVAKACKTTFQAC 204


>gi|47578111 hypothetical protein LOC140699 isoform 2 [Homo sapiens]
          Length = 608

 Score = 91.3 bits (225), Expect = 7e-18
 Identities = 85/426 (19%), Positives = 183/426 (42%), Gaps = 28/426 (6%)

Query: 835  PITAKIIHHYVSSCQDI--------CLKMAFMKSVVQVTKAINNIKDLEDFHFAQKTTLT 886
            P++  I+   + S Q +          K+ F+  +  +++A+   +  + F  +    + 
Sbjct: 163  PLSEAIVEKLIQSIQKVFNGELKGELEKLKFLGDLSSLSQALPYDETAKSFIHSHIADIV 222

Query: 887  SIIVAVIKAEPTDNLVSPVRALAMEALSHLS--KLKPFYSTEENSELMDISIHSVISL-- 942
              +  +++ E   +L S +R      ++ LS   +     +E+ +EL  ++I S+I+L  
Sbjct: 223  HTLNVLVQEERPHSLSSSMRQEVFVTIADLSYQDVHLLLGSEDRAELFSLTIKSIITLPS 282

Query: 943  --------QLPGEDNESIKTLYANALSSLEQLMESLLQRQLDPKGLQEMVQLLEKWILSE 994
                    ++      + + LY     +  ++++SL+ +    + L  +++ L  W+ S 
Sbjct: 283  VRTLTQIQEIMPNGTCNTECLYRQTFQAFSEMLQSLVVKDPHLENLDTIIKHLVPWLQSV 342

Query: 995  KEWEREKAVSLHLYLMRIYVHSTAVCIHLKLGQFGTMVGLIAPCTCDAHQRTRMASMNVL 1054
            K+ ERE+A +    +++       + + L+  + G +V L+A    D  ++    +   +
Sbjct: 343  KDHERERATASMAQVLKCLSKHLNLKLPLRFQRLGHLVALMALLCGDPQEKVAEEAAEGI 402

Query: 1055 SSLLDLHASQTCSLWGPSKQKELE----KCKG--DLQSTDVEKIFCASSRIAKVVCMEFS 1108
             SLL +             Q+ L+    KC+   +L S+  +  +    RIA+V      
Sbjct: 403  HSLLHITLRLKYITHDKKDQQNLKRALTKCREFLELHSSAAKCFYNCPFRIAQVFEGFLD 462

Query: 1109 CDEVVSLIQKLCENTGAMNLQHDKASVTWIASFLQMRAKELEDKVAEILSAILVHLPVVD 1168
             +E+   I    +    +     + S   +   L    +   +KV EI+  I   L ++ 
Sbjct: 463  SNELCQFIMTTFDTLKTLKHPCIQRSAGELLLTLAKNTESQFEKVPEIMGVICAQLSIIS 522

Query: 1169 HPEVRRLLIDGILLLAHH--HQETILTSLLRQPLPMESHLAEVWLAVSENVPFARTMLHS 1226
             P VR+ +I+ + L      + + +L+ LL  P+P   HLAEVW  +S  +P    +L  
Sbjct: 523  QPRVRQQIINTVSLFISRPKYTDIVLSFLLCHPVPYNRHLAEVWRMLSVELPSTTWILWR 582

Query: 1227 LMGRLQ 1232
            L+ +LQ
Sbjct: 583  LLRKLQ 588


>gi|47578113 hypothetical protein LOC140699 isoform 3 [Homo sapiens]
          Length = 573

 Score = 68.2 bits (165), Expect = 7e-11
 Identities = 87/424 (20%), Positives = 176/424 (41%), Gaps = 59/424 (13%)

Query: 835  PITAKIIHHYVSSCQDI--------CLKMAFMKSVVQVTKAINNIKDLEDFHFAQKTTLT 886
            P++  I+   + S Q +          K+ F+  +  +++A+   +  + F  +    + 
Sbjct: 163  PLSEAIVEKLIQSIQKVFNGELKGELEKLKFLGDLSSLSQALPYDETAKSFIHSHIADIV 222

Query: 887  SIIVAVIKAEPTDNLVSPVRALAMEALSHLS--KLKPFYSTEENSELMDISIHSVISLQL 944
              +  +++ E   +L S +R      ++ LS   +     +E+ +EL  ++I S+I+L  
Sbjct: 223  HTLNVLVQEERPHSLSSSMRQEVFVTIADLSYQDVHLLLGSEDRAELFSLTIKSIITLP- 281

Query: 945  PGEDNESIKTLYANALSSLEQLMES------LLQRQLDPKGLQEMVQLLEKWILSEKEWE 998
                  S++TL     + ++++M +       L RQ      Q   ++L+  ++ +   E
Sbjct: 282  ------SVRTL-----TQIQEIMPNGTCNTECLYRQT----FQAFSEMLQSLVVKDPHLE 326

Query: 999  REKAVSLHLYLMRIYVHSTAVCIHLKLGQFGTMVGLIAPCTCDAHQRTRMASMNVLSSLL 1058
                              T + + L+  + G +V L+A    D  ++    +   + SLL
Sbjct: 327  NL---------------DTIIKLPLRFQRLGHLVALMALLCGDPQEKVAEEAAEGIHSLL 371

Query: 1059 DLHASQTCSLWGPSKQKELE----KCKG--DLQSTDVEKIFCASSRIAKVVCMEFSCDEV 1112
             +             Q+ L+    KC+   +L S+  +  +    RIA+V       +E+
Sbjct: 372  HITLRLKYITHDKKDQQNLKRALTKCREFLELHSSAAKCFYNCPFRIAQVFEGFLDSNEL 431

Query: 1113 VSLIQKLCENTGAMNLQHD--KASVTWIASFLQMRAKELEDKVAEILSAILVHLPVVDHP 1170
               I    +     NL+H   + S   +   L    +   +KV EI+  I   L ++  P
Sbjct: 432  CQFIMTTFDTL--KNLKHPCIQRSAGELLLTLAKNTESQFEKVPEIMGVICAQLSIISQP 489

Query: 1171 EVRRLLIDGILLLAHHHQET--ILTSLLRQPLPMESHLAEVWLAVSENVPFARTMLHSLM 1228
             VR+ +I+ + L     + T  +L+ LL  P+P   HLAEVW  +S  +P    +L  L+
Sbjct: 490  RVRQQIINTVSLFISRPKYTDIVLSFLLCHPVPYNRHLAEVWRMLSVELPSTTWILWRLL 549

Query: 1229 GRLQ 1232
             +LQ
Sbjct: 550  RKLQ 553


>gi|187761379 maestro isoform c [Homo sapiens]
          Length = 210

 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 33/103 (32%), Positives = 58/103 (56%), Gaps = 2/103 (1%)

Query: 1420 QEKLLKPAALLLEKGADQEEDEALRVLSLRALGNMALGAPKKVKQYRKVLLEKCLGPLRE 1479
            +E L     +L E+  D    +  R +++R LG MA  AP KV++Y+K++L+  +  L +
Sbjct: 57   REPLKNVFFILAERARDPSAKK--RHMAMRNLGTMAYEAPDKVRKYKKIVLDLLVYGLYD 114

Query: 1480 PVSNSVTAEGMEALTKILAELREGDVGSSFDAMSEQCRIFFDN 1522
            PV+  V  E M+ LT +L +++   +GS F  ++ Q R   D+
Sbjct: 115  PVNLEVIHESMKTLTVVLGKIQGKGLGSFFIDITLQTRTLLDD 157


>gi|187761377 maestro isoform b [Homo sapiens]
          Length = 196

 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 33/103 (32%), Positives = 58/103 (56%), Gaps = 2/103 (1%)

Query: 1420 QEKLLKPAALLLEKGADQEEDEALRVLSLRALGNMALGAPKKVKQYRKVLLEKCLGPLRE 1479
            +E L     +L E+  D    +  R +++R LG MA  AP KV++Y+K++L+  +  L +
Sbjct: 43   REPLKNVFFILAERARDPSAKK--RHMAMRNLGTMAYEAPDKVRKYKKIVLDLLVYGLYD 100

Query: 1480 PVSNSVTAEGMEALTKILAELREGDVGSSFDAMSEQCRIFFDN 1522
            PV+  V  E M+ LT +L +++   +GS F  ++ Q R   D+
Sbjct: 101  PVNLEVIHESMKTLTVVLGKIQGKGLGSFFIDITLQTRTLLDD 143


>gi|117956387 hypothetical protein LOC80133 [Homo sapiens]
          Length = 573

 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 86/449 (19%), Positives = 175/449 (38%), Gaps = 64/449 (14%)

Query: 950  ESIKTLYANALSSLEQLMESLLQRQLDPKGLQEMVQLLEKWILSEKEWERE-------KA 1002
            E ++ LY N L+  E ++ SL+ + L    LQ + ++L  W+  +  + +E       K 
Sbjct: 93   EDMENLYHNILNIYENILTSLVSKDLYK--LQILKEMLV-WMSKDSSYLQERIMVIINKV 149

Query: 1003 VSLHLYLMRIYVHSTAVCIHLKLGQFGTMVGLIAPCTCDAHQRTRMASMNVLSSLLDLHA 1062
            +   +  +R Y+   A C+ L   +   +      C+ +     + AS+ +   L     
Sbjct: 150  LRFTVTKVRKYISVDAPCLGLLAAELSLL------CSHEDPSIVKQASLGMCHLLYIARC 203

Query: 1063 SQTCSLWGPS--KQKELEKCKGDLQ------STDVEKIFCASSRIAKVVCMEFSCDEVVS 1114
                    P+  K   L+    D++        D  KI   + R+ + +      D V S
Sbjct: 204  QNDIGTNKPTNGKSHSLQFPSSDVEFLPKEFQQDESKI---AQRVGQTLLPPLLTDFVQS 260

Query: 1115 LIQKLCENTGAMNLQHDKASVTWIASFLQMRAKELEDKVAEILSAILVHLPVVDHPEVRR 1174
            L+ KL        +  D AS+  +   L+  A+++   V++I+ AI   L   D+  ++ 
Sbjct: 261  LLMKLSSPDD--KIASDAASI--LIFTLEFHAEKVT-MVSKIVDAIYRQL--CDNNCMKD 313

Query: 1175 LLIDGILLLAHHHQETILTSLLRQPLPMESHLAEVWLAVSENVPFARTMLHSLMGRLQSR 1234
            +++  I LL     + ++  L+  P+P +  L ++W A       A  +L +++  L+ +
Sbjct: 314  VMLQVITLLTCTSPKKVIFQLMDYPVPADDTLIQMWKAACSQASVAPHVLKTILLILKGK 373

Query: 1235 LSPRISATSKA-----DIWRLAAVDPLMTLCTIHLLIQKLDENDKLPDFLPDLIYTLLLQ 1289
                    ++      DI  L  +     LCT    +        +  + P L+ TL+ Q
Sbjct: 374  PGEMEDTVTEGKRFSLDITNLMPLAACQALCT---FLPLGSYRKAVAQYFPQLLTTLMFQ 430

Query: 1290 LGSSHRPEAAPPVLKMWKLVHTTPLPEEMNLQRCSRGRVTIKSMQLLFKRVKSQHLAHTL 1349
            +  +       P+LK                    R      ++++L      Q +  TL
Sbjct: 431  VFYN---SELKPILK-------------------DRALYAQDALRVLLNCSGLQQVDITL 468

Query: 1350 DEQAVWDLLQDGGTFLEGVSLLARLCMQH 1378
             ++  WD L +   +  GV  +A+   ++
Sbjct: 469  MKENFWDQLSEDLCYYHGVCFIAKTLSEY 497


>gi|21071077 dishevelled-associated activator of morphogenesis 1
           [Homo sapiens]
          Length = 1078

 Score = 35.4 bits (80), Expect = 0.48
 Identities = 23/102 (22%), Positives = 46/102 (45%), Gaps = 6/102 (5%)

Query: 429 ETNKEAVRVGTLNLIRAIVSADEPRMSIRAIYLAIRVVKNTISDTRSKVRMAILHIIGQL 488
           ET++  +    +  I+A+++  + R  + A   +I V+  ++S    K ++A+L I+G +
Sbjct: 171 ETSESRIHTSLIGCIKALMNNSQGRAHVLAHSESINVIAQSLSTENIKTKVAVLEILGAV 230

Query: 489 ALCGYQERIKGWGLKYLSVQLTLSTYKLTNRREKFYQRDLEE 530
            L      + G   K L   L    Y     R +    DL++
Sbjct: 231 CL------VPGGHKKVLQAMLHYQKYASERTRFQTLINDLDK 266


>gi|57634534 nucleoporin 205kDa [Homo sapiens]
          Length = 2012

 Score = 35.0 bits (79), Expect = 0.63
 Identities = 31/122 (25%), Positives = 54/122 (44%), Gaps = 26/122 (21%)

Query: 675 WEDKLIQFLRNSLK----KTRGSSWSLRLSKELNNQIASFDSPSLEKGFLYRALGFTLAT 730
           W+ K  + + NSLK      RG +W+L LS EL +    F    +E+G  Y+        
Sbjct: 136 WDGK--RCIANSLKALIQSRRGKTWTLELSPELASMTTRFTDELMEQGLTYK-------- 185

Query: 731 GLEASKVEVLLLELLYKTDYSNDFDSEGVIMCFGLCARGQVKTVLNVLHDFEERIQESEQ 790
                     +L L+ + D +N+F  E +    GL +    K V +++ +  + + ES  
Sbjct: 186 ----------VLTLVSQIDVNNEF--EKLQRERGLGSEKHRKEVSDLIKECRQSLAESLF 233

Query: 791 SW 792
           +W
Sbjct: 234 AW 235


>gi|22749269 ring finger protein 129 [Homo sapiens]
          Length = 471

 Score = 34.3 bits (77), Expect = 1.1
 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 8/72 (11%)

Query: 1460 KKVKQYRKVLLEKCLGPLR---EPVSNSVTAEGMEAL-TKILAELREGDVGSSFDAMSEQ 1515
            KK   Y + +LE  L PLR   E V   +  +G +++  K   E +  ++ S F    EQ
Sbjct: 134  KKAASYHREILEGSLEPLRNNIERVEKVIILQGSKSVELKKKVEYKREEINSEF----EQ 189

Query: 1516 CRIFFDNESELL 1527
             R+F  NE E++
Sbjct: 190  IRLFLQNEQEMI 201


>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
          Length = 983

 Score = 34.3 bits (77), Expect = 1.1
 Identities = 44/194 (22%), Positives = 82/194 (42%), Gaps = 15/194 (7%)

Query: 23  LRKELEEEMTEAITEAAVDSSEEVSEERDDLGPLELHDSGTFQQVVNLLDIIDSESAKTD 82
           L+  L+ +MT+  ++ A D  E ++   D+L       S  +++    L+      +  D
Sbjct: 614 LKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLED 673

Query: 83  TTGAGLD-------MRKTLASVIIMEKATTEP----SVVINTLIRCLQVPEISTQRKVNI 131
            T   +        M+ T  S    E A +E     S V+N L +  Q+ +   +  V+I
Sbjct: 674 VTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSI 733

Query: 132 YNILQDII---QQEGELEEQCVQRLVAIASKEMREIPEMEGYMKAEVASDTLVALSRNHF 188
              LQ I        E+EE+       +ASKE+ E+ ++E  +  E A+ T   + R+ +
Sbjct: 734 TEHLQVITTLRTAAKEMEEKISNLKEHLASKEV-EVAKLEKQLLEEKAAMTDAMVPRSSY 792

Query: 189 SLVMYELQHHLKPL 202
             +   L+  +  L
Sbjct: 793 EKLQSSLESEVSVL 806


>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
          Length = 972

 Score = 34.3 bits (77), Expect = 1.1
 Identities = 44/194 (22%), Positives = 82/194 (42%), Gaps = 15/194 (7%)

Query: 23  LRKELEEEMTEAITEAAVDSSEEVSEERDDLGPLELHDSGTFQQVVNLLDIIDSESAKTD 82
           L+  L+ +MT+  ++ A D  E ++   D+L       S  +++    L+      +  D
Sbjct: 603 LKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLED 662

Query: 83  TTGAGLD-------MRKTLASVIIMEKATTEP----SVVINTLIRCLQVPEISTQRKVNI 131
            T   +        M+ T  S    E A +E     S V+N L +  Q+ +   +  V+I
Sbjct: 663 VTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSI 722

Query: 132 YNILQDII---QQEGELEEQCVQRLVAIASKEMREIPEMEGYMKAEVASDTLVALSRNHF 188
              LQ I        E+EE+       +ASKE+ E+ ++E  +  E A+ T   + R+ +
Sbjct: 723 TEHLQVITTLRTAAKEMEEKISNLKEHLASKEV-EVAKLEKQLLEEKAAMTDAMVPRSSY 781

Query: 189 SLVMYELQHHLKPL 202
             +   L+  +  L
Sbjct: 782 EKLQSSLESEVSVL 795


>gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]
          Length = 951

 Score = 34.3 bits (77), Expect = 1.1
 Identities = 44/194 (22%), Positives = 82/194 (42%), Gaps = 15/194 (7%)

Query: 23  LRKELEEEMTEAITEAAVDSSEEVSEERDDLGPLELHDSGTFQQVVNLLDIIDSESAKTD 82
           L+  L+ +MT+  ++ A D  E ++   D+L       S  +++    L+      +  D
Sbjct: 582 LKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLED 641

Query: 83  TTGAGLD-------MRKTLASVIIMEKATTEP----SVVINTLIRCLQVPEISTQRKVNI 131
            T   +        M+ T  S    E A +E     S V+N L +  Q+ +   +  V+I
Sbjct: 642 VTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSI 701

Query: 132 YNILQDII---QQEGELEEQCVQRLVAIASKEMREIPEMEGYMKAEVASDTLVALSRNHF 188
              LQ I        E+EE+       +ASKE+ E+ ++E  +  E A+ T   + R+ +
Sbjct: 702 TEHLQVITTLRTAAKEMEEKISNLKEHLASKEV-EVAKLEKQLLEEKAAMTDAMVPRSSY 760

Query: 189 SLVMYELQHHLKPL 202
             +   L+  +  L
Sbjct: 761 EKLQSSLESEVSVL 774


>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 34.3 bits (77), Expect = 1.1
 Identities = 44/194 (22%), Positives = 82/194 (42%), Gaps = 15/194 (7%)

Query: 23  LRKELEEEMTEAITEAAVDSSEEVSEERDDLGPLELHDSGTFQQVVNLLDIIDSESAKTD 82
           L+  L+ +MT+  ++ A D  E ++   D+L       S  +++    L+      +  D
Sbjct: 611 LKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLED 670

Query: 83  TTGAGLD-------MRKTLASVIIMEKATTEP----SVVINTLIRCLQVPEISTQRKVNI 131
            T   +        M+ T  S    E A +E     S V+N L +  Q+ +   +  V+I
Sbjct: 671 VTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSI 730

Query: 132 YNILQDII---QQEGELEEQCVQRLVAIASKEMREIPEMEGYMKAEVASDTLVALSRNHF 188
              LQ I        E+EE+       +ASKE+ E+ ++E  +  E A+ T   + R+ +
Sbjct: 731 TEHLQVITTLRTAAKEMEEKISNLKEHLASKEV-EVAKLEKQLLEEKAAMTDAMVPRSSY 789

Query: 189 SLVMYELQHHLKPL 202
             +   L+  +  L
Sbjct: 790 EKLQSSLESEVSVL 803


>gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 34.3 bits (77), Expect = 1.1
 Identities = 44/194 (22%), Positives = 82/194 (42%), Gaps = 15/194 (7%)

Query: 23  LRKELEEEMTEAITEAAVDSSEEVSEERDDLGPLELHDSGTFQQVVNLLDIIDSESAKTD 82
           L+  L+ +MT+  ++ A D  E ++   D+L       S  +++    L+      +  D
Sbjct: 611 LKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLED 670

Query: 83  TTGAGLD-------MRKTLASVIIMEKATTEP----SVVINTLIRCLQVPEISTQRKVNI 131
            T   +        M+ T  S    E A +E     S V+N L +  Q+ +   +  V+I
Sbjct: 671 VTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSI 730

Query: 132 YNILQDII---QQEGELEEQCVQRLVAIASKEMREIPEMEGYMKAEVASDTLVALSRNHF 188
              LQ I        E+EE+       +ASKE+ E+ ++E  +  E A+ T   + R+ +
Sbjct: 731 TEHLQVITTLRTAAKEMEEKISNLKEHLASKEV-EVAKLEKQLLEEKAAMTDAMVPRSSY 789

Query: 189 SLVMYELQHHLKPL 202
             +   L+  +  L
Sbjct: 790 EKLQSSLESEVSVL 803


>gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 34.3 bits (77), Expect = 1.1
 Identities = 44/194 (22%), Positives = 82/194 (42%), Gaps = 15/194 (7%)

Query: 23  LRKELEEEMTEAITEAAVDSSEEVSEERDDLGPLELHDSGTFQQVVNLLDIIDSESAKTD 82
           L+  L+ +MT+  ++ A D  E ++   D+L       S  +++    L+      +  D
Sbjct: 611 LKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLED 670

Query: 83  TTGAGLD-------MRKTLASVIIMEKATTEP----SVVINTLIRCLQVPEISTQRKVNI 131
            T   +        M+ T  S    E A +E     S V+N L +  Q+ +   +  V+I
Sbjct: 671 VTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSI 730

Query: 132 YNILQDII---QQEGELEEQCVQRLVAIASKEMREIPEMEGYMKAEVASDTLVALSRNHF 188
              LQ I        E+EE+       +ASKE+ E+ ++E  +  E A+ T   + R+ +
Sbjct: 731 TEHLQVITTLRTAAKEMEEKISNLKEHLASKEV-EVAKLEKQLLEEKAAMTDAMVPRSSY 789

Query: 189 SLVMYELQHHLKPL 202
             +   L+  +  L
Sbjct: 790 EKLQSSLESEVSVL 803


>gi|32526896 armadillo repeat containing 8 isoform 2 [Homo sapiens]
          Length = 659

 Score = 33.9 bits (76), Expect = 1.4
 Identities = 27/77 (35%), Positives = 42/77 (54%), Gaps = 9/77 (11%)

Query: 1390 VLRGMDSEVLSCRISSTAVC---VEFMSGPVLYQEKLLKPAALLLEKGADQEEDEALRVL 1446
            VL+    E+L   ++S+ +C   +EF       +E +L+  A+ L  G  Q E+ ALRV 
Sbjct: 420  VLQNAPDEILV--VASSMLCNLLLEFSPS----KEPILESGAVELLCGLTQSENPALRVN 473

Query: 1447 SLRALGNMALGAPKKVK 1463
             + AL NMA  A +K+K
Sbjct: 474  GIWALMNMAFQAEQKIK 490


>gi|12083581 phosphoinositide-specific phospholipase C beta 1 isoform
            a [Homo sapiens]
          Length = 1216

 Score = 31.6 bits (70), Expect = 7.0
 Identities = 13/39 (33%), Positives = 25/39 (64%)

Query: 15   ICLIQKKTLRKELEEEMTEAITEAAVDSSEEVSEERDDL 53
            IC  +KK L+K+++++  E ITEA      ++ EE+ ++
Sbjct: 1060 ICEKEKKELKKKMDKKRQEKITEAKSKDKSQMEEEKTEM 1098


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.134    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,592,916
Number of Sequences: 37866
Number of extensions: 2586812
Number of successful extensions: 7196
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 7079
Number of HSP's gapped (non-prelim): 62
length of query: 1723
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1607
effective length of database: 13,855,062
effective search space: 22265084634
effective search space used: 22265084634
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.