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Search of human proteins with 118572599
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|118572599 formin homology 2 domain containing 1 [Homo
sapiens]
(1164 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|118572599 formin homology 2 domain containing 1 [Homo sapiens] 2297 0.0
gi|58331242 formin homology 2 domain containing 3 [Homo sapiens] 624 e-178
gi|32880208 diaphanous homolog 3 isoform b [Homo sapiens] 139 2e-32
gi|110225351 diaphanous homolog 3 isoform a [Homo sapiens] 139 2e-32
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 133 9e-31
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 133 9e-31
gi|40548415 dishevelled associated activator of morphogenesis 2 ... 129 2e-29
gi|33356148 formin-like 1 [Homo sapiens] 119 2e-26
gi|21071077 dishevelled-associated activator of morphogenesis 1 ... 117 8e-26
gi|6382071 diaphanous 2 isoform 12C [Homo sapiens] 112 2e-24
gi|5803003 diaphanous 2 isoform 156 [Homo sapiens] 112 2e-24
gi|157168329 formin 1 [Homo sapiens] 112 2e-24
gi|52485606 formin-like 2 [Homo sapiens] 108 2e-23
gi|119120861 formin-like 3 isoform 2 [Homo sapiens] 107 7e-23
gi|119120874 formin-like 3 isoform 1 [Homo sapiens] 107 7e-23
gi|160707881 formin 2 [Homo sapiens] 102 2e-21
gi|149999378 inverted formin 2 isoform 2 [Homo sapiens] 100 1e-20
gi|149999380 inverted formin 2 isoform 1 [Homo sapiens] 100 1e-20
gi|223278403 glutamate receptor, ionotropic, delta 2 (Grid2) int... 86 3e-16
gi|145309324 FH2 domain containing 1 [Homo sapiens] 83 2e-15
gi|153792074 proline rich 12 [Homo sapiens] 76 2e-13
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 60 9e-09
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 60 9e-09
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 60 9e-09
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 59 2e-08
gi|149944526 additional sex combs like 3 [Homo sapiens] 59 4e-08
gi|56549694 enabled homolog isoform a [Homo sapiens] 58 5e-08
gi|39930375 enabled homolog isoform b [Homo sapiens] 58 5e-08
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 58 5e-08
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 58 5e-08
>gi|118572599 formin homology 2 domain containing 1 [Homo sapiens]
Length = 1164
Score = 2297 bits (5952), Expect = 0.0
Identities = 1164/1164 (100%), Positives = 1164/1164 (100%)
Query: 1 MAGGEDRGDGEPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLGAQIPAVHR 60
MAGGEDRGDGEPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLGAQIPAVHR
Sbjct: 1 MAGGEDRGDGEPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLGAQIPAVHR 60
Query: 61 LLGAPLKLEDCALQVSPSGYYLDTELSLEEQREMLEGFYEEISKGRKPTLILRTQLSVRV 120
LLGAPLKLEDCALQVSPSGYYLDTELSLEEQREMLEGFYEEISKGRKPTLILRTQLSVRV
Sbjct: 61 LLGAPLKLEDCALQVSPSGYYLDTELSLEEQREMLEGFYEEISKGRKPTLILRTQLSVRV 120
Query: 121 NAILEKLYSSSGPELRRSLFSLKQIFQEDKDLVPEFVHSEGLSCLIRVGAAADHNYQSYI 180
NAILEKLYSSSGPELRRSLFSLKQIFQEDKDLVPEFVHSEGLSCLIRVGAAADHNYQSYI
Sbjct: 121 NAILEKLYSSSGPELRRSLFSLKQIFQEDKDLVPEFVHSEGLSCLIRVGAAADHNYQSYI 180
Query: 181 LRALGQLMLFVDGMLGVVAHSDTIQWLYTLCASLSRLVVKTALKLLLVFVEYSENNAPLF 240
LRALGQLMLFVDGMLGVVAHSDTIQWLYTLCASLSRLVVKTALKLLLVFVEYSENNAPLF
Sbjct: 181 LRALGQLMLFVDGMLGVVAHSDTIQWLYTLCASLSRLVVKTALKLLLVFVEYSENNAPLF 240
Query: 241 IRAVNSVASTTGAPPWANLVSILEEKNGADPELLVYTVTLINKTLAALPDQDSFYDVTDA 300
IRAVNSVASTTGAPPWANLVSILEEKNGADPELLVYTVTLINKTLAALPDQDSFYDVTDA
Sbjct: 241 IRAVNSVASTTGAPPWANLVSILEEKNGADPELLVYTVTLINKTLAALPDQDSFYDVTDA 300
Query: 301 LEQQGMEALVQRHLGTAGTDVDLRTQLVLYENALKLEDGDIEEAPGAGGRRERRKPSSEE 360
LEQQGMEALVQRHLGTAGTDVDLRTQLVLYENALKLEDGDIEEAPGAGGRRERRKPSSEE
Sbjct: 301 LEQQGMEALVQRHLGTAGTDVDLRTQLVLYENALKLEDGDIEEAPGAGGRRERRKPSSEE 360
Query: 361 GKRSRRSLEGGGCPARAPEPGPTGPASPVGPTSSTGPALLTGPASSPVGPPSGLQASVNL 420
GKRSRRSLEGGGCPARAPEPGPTGPASPVGPTSSTGPALLTGPASSPVGPPSGLQASVNL
Sbjct: 361 GKRSRRSLEGGGCPARAPEPGPTGPASPVGPTSSTGPALLTGPASSPVGPPSGLQASVNL 420
Query: 421 FPTISVAPSADTSSERSIYKARFLENVAAAETEKQVALAQGRAETLAGAMPNEAGGHPDA 480
FPTISVAPSADTSSERSIYKARFLENVAAAETEKQVALAQGRAETLAGAMPNEAGGHPDA
Sbjct: 421 FPTISVAPSADTSSERSIYKARFLENVAAAETEKQVALAQGRAETLAGAMPNEAGGHPDA 480
Query: 481 RQLWDSPETAPAARTPQSPAPCVLLRAQRSLAPEPKEPLIPASPKAEPIWELPTRAPRLS 540
RQLWDSPETAPAARTPQSPAPCVLLRAQRSLAPEPKEPLIPASPKAEPIWELPTRAPRLS
Sbjct: 481 RQLWDSPETAPAARTPQSPAPCVLLRAQRSLAPEPKEPLIPASPKAEPIWELPTRAPRLS 540
Query: 541 IGDLDFSDLGEDEDQDMLNVESVEAGKDIPAPSPPLPLLSGVPPPPPLPPPPPIKGPFPP 600
IGDLDFSDLGEDEDQDMLNVESVEAGKDIPAPSPPLPLLSGVPPPPPLPPPPPIKGPFPP
Sbjct: 541 IGDLDFSDLGEDEDQDMLNVESVEAGKDIPAPSPPLPLLSGVPPPPPLPPPPPIKGPFPP 600
Query: 601 PPPLPLAAPLPHSVPDSSALPTKRKTVKLFWRELKLAGGHGVSASRFGPCATLWASLDPV 660
PPPLPLAAPLPHSVPDSSALPTKRKTVKLFWRELKLAGGHGVSASRFGPCATLWASLDPV
Sbjct: 601 PPPLPLAAPLPHSVPDSSALPTKRKTVKLFWRELKLAGGHGVSASRFGPCATLWASLDPV 660
Query: 661 SVDTARLEHLFESRAKEVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVHVIKAAL 720
SVDTARLEHLFESRAKEVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVHVIKAAL
Sbjct: 661 SVDTARLEHLFESRAKEVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVHVIKAAL 720
Query: 721 LNFDEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDIPLGPAENFLMTLASIGGLAAR 780
LNFDEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDIPLGPAENFLMTLASIGGLAAR
Sbjct: 721 LNFDEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDIPLGPAENFLMTLASIGGLAAR 780
Query: 781 LQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAVGNFLNGSQSSGFE 840
LQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAVGNFLNGSQSSGFE
Sbjct: 781 LQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAVGNFLNGSQSSGFE 840
Query: 841 LSYLEKVSEVKDTVRRQSLLHHLCSLVLQTRPESSDLYSEIPALTRCAKVDFEQLTENLG 900
LSYLEKVSEVKDTVRRQSLLHHLCSLVLQTRPESSDLYSEIPALTRCAKVDFEQLTENLG
Sbjct: 841 LSYLEKVSEVKDTVRRQSLLHHLCSLVLQTRPESSDLYSEIPALTRCAKVDFEQLTENLG 900
Query: 901 QLERRSRAAEESLRSLAKHELAPALRARLTHFLDQCARRVAMLRIVHRRVCNRFHAFLLY 960
QLERRSRAAEESLRSLAKHELAPALRARLTHFLDQCARRVAMLRIVHRRVCNRFHAFLLY
Sbjct: 901 QLERRSRAAEESLRSLAKHELAPALRARLTHFLDQCARRVAMLRIVHRRVCNRFHAFLLY 960
Query: 961 LGYTPQAAREVRIMQFCHTLREFALEYRTCRERVLQQQQKQATYRERNKTRGRMITETEK 1020
LGYTPQAAREVRIMQFCHTLREFALEYRTCRERVLQQQQKQATYRERNKTRGRMITETEK
Sbjct: 961 LGYTPQAAREVRIMQFCHTLREFALEYRTCRERVLQQQQKQATYRERNKTRGRMITETEK 1020
Query: 1021 FSGVAGEAPSNPSVPVAVSSGPGRGDADSHASMKSLLTSRPEDTTHNRRSRGMVQSSSPI 1080
FSGVAGEAPSNPSVPVAVSSGPGRGDADSHASMKSLLTSRPEDTTHNRRSRGMVQSSSPI
Sbjct: 1021 FSGVAGEAPSNPSVPVAVSSGPGRGDADSHASMKSLLTSRPEDTTHNRRSRGMVQSSSPI 1080
Query: 1081 MPTVGPSTASPEEPPGSSLPSDTSDEIMDLLVQSVTKSSPRALAARERKRSRGNRKSLRR 1140
MPTVGPSTASPEEPPGSSLPSDTSDEIMDLLVQSVTKSSPRALAARERKRSRGNRKSLRR
Sbjct: 1081 MPTVGPSTASPEEPPGSSLPSDTSDEIMDLLVQSVTKSSPRALAARERKRSRGNRKSLRR 1140
Query: 1141 TLKSGLGDDLVQALGLSKGPGLEV 1164
TLKSGLGDDLVQALGLSKGPGLEV
Sbjct: 1141 TLKSGLGDDLVQALGLSKGPGLEV 1164
>gi|58331242 formin homology 2 domain containing 3 [Homo sapiens]
Length = 1439
Score = 624 bits (1610), Expect = e-178
Identities = 351/672 (52%), Positives = 458/672 (68%), Gaps = 53/672 (7%)
Query: 513 PEPKEP-LIPASPKAEP--IWELPTRAPR-LSIGDLDFSDLGEDEDQDMLNVESVEAGKD 568
P K P P PK E IW+ PR L I D+DF+DLGE++D D+L+V+
Sbjct: 785 PNDKVPETAPVQPKTESDYIWDQLMANPRELRIQDMDFTDLGEEDDIDVLDVDLGHREAP 844
Query: 569 IPAPSPPLPLLSGVPPPPPLP-----PPPPIKGPFPPPPPLPLAAP-------LPHSVPD 616
P P PP P G+PPPPP P PPPP+ G PPP AP +P P
Sbjct: 845 GPPPPPP-PTFLGLPPPPPPPLLDSIPPPPVPGNLLVPPPPVFNAPQGLGWSQVPRGQP- 902
Query: 617 SSALPTKRKTVKLFWRELKLAGGHGVSASRFGPCAT-LWASLDPVSVDTARLEHLFESRA 675
K+KT++LFW E++ + R C LW+ L+P+ VDT+RLEHLFES++
Sbjct: 903 --TFTKKKKTIRLFWNEVRPFDWPCKNNRR---CREFLWSKLEPIKVDTSRLEHLFESKS 957
Query: 676 KEVLPSKK-AGEGRRTMTTVLDPKRSNAINIGLTTLPPVHVIKAALLNFDEFAVSKDGIE 734
KE+ SKK A +G+R VLD KRSNAINIGLT LPP IK A+LNFDE+A++K+GIE
Sbjct: 958 KELSVSKKTAADGKRQEIIVLDSKRSNAINIGLTVLPPPRTIKIAILNFDEYALNKEGIE 1017
Query: 735 KLLTMMPTEEERQKIEEAQLANPDIPLGPAENFLMTLASIGGLAARLQLWAFKLDYDSME 794
K+LTM+PT+EE+QKI+EAQLANP+IPLG AE FL+TL+SI L+ARL LWAFK+DY++ E
Sbjct: 1018 KILTMIPTDEEKQKIQEAQLANPEIPLGSAEQFLLTLSSISELSARLHLWAFKMDYETTE 1077
Query: 795 REIAEPLFDLKVGMEQLVQNATFRCILATLLAVGNFLNGSQSSGFELSYLEKVSEVKDTV 854
+E+AEPL DLK G++QL N T IL+TLLA+GNFLNG+ + FELSYLEKV EVKDTV
Sbjct: 1078 KEVAEPLLDLKEGIDQLENNKTLGFILSTLLAIGNFLNGTNAKAFELSYLEKVPEVKDTV 1137
Query: 855 RRQSLLHHLCSLVLQTRPESSDLYSEIPALTRCAKVDFEQLTENLGQLERRSRAAEESLR 914
+QSLLHH+C++V++ P+SSDLYSEI A+TR AKVDF+QL +NL Q+ERR +A+ + L+
Sbjct: 1138 HKQSLLHHVCTMVVENFPDSSDLYSEIGAITRSAKVDFDQLQDNLCQMERRCKASWDHLK 1197
Query: 915 SLAKHELAPALRARLTHFLDQCARRVAMLRIVHRRVCNRFHAFLLYLGYTPQAAREVRIM 974
++AKHE+ P L+ R++ FL CA R+ +L+IVHRR+ NRFH+FLL++G+ P A REV I
Sbjct: 1198 AIAKHEMKPVLKQRMSEFLKDCAERIIILKIVHRRIINRFHSFLLFMGHPPYAIREVNIN 1257
Query: 975 QFCHTLREFALEYRTCRERVLQQQQKQATYRERNKTRGRMITETEKFSGVAGEAPSNPSV 1034
+FC + EFALEYRT RERVLQQ+QK+A +RERNKTRG+MIT++ KFS G +P+ PS
Sbjct: 1258 KFCRIISEFALEYRTTRERVLQQKQKRANHRERNKTRGKMITDSGKFS---GSSPAPPSQ 1314
Query: 1035 PVAVSSGPGRGDADSHASMKSLL-TSRP--EDT-------THNRRSRGMVQSSSPIMPTV 1084
P +S DA H +MK++L TS P ED T +R SRG S
Sbjct: 1315 PQGLSYAE---DAAEHENMKAVLKTSSPSVEDATPALGVRTRSRASRGSTSS-------- 1363
Query: 1085 GPSTASPEEPPGSSLPSDTSDEIMDLLVQSVTKSSPRALAARERKRSRGNRKSLRRTLKS 1144
T ++ P ++ D +DEIMD +V+S T+ + + RERKRSR NRKSLRRTLKS
Sbjct: 1364 --WTMGTDDSP--NVTDDAADEIMDRIVKSATQVPSQRVVPRERKRSRANRKSLRRTLKS 1419
Query: 1145 GLGDDLVQALGL 1156
GL + +ALGL
Sbjct: 1420 GLTPEEARALGL 1431
Score = 432 bits (1110), Expect = e-120
Identities = 238/440 (54%), Positives = 297/440 (67%), Gaps = 17/440 (3%)
Query: 13 VSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLGAQIPAVHRLLGAPLKLEDCA 72
++ + RVQ+L+DTDPF NFPEP R P + L LG Q+ VHRLL AP KL+DC
Sbjct: 1 MATLACRVQFLDDTDPFNSTNFPEPSRPPLFTFREDLALGTQLAGVHRLLQAPHKLDDCT 60
Query: 73 LQVSPSGYYLDTELSLEEQREMLEGFYEEISKGRKPTLILRTQLSVRVNAILEKLYSSSG 132
LQ+S +G YLD E +L EQR+ LEGF ++ +G+K ++ILRTQLSVRV+A +EKLY+SSG
Sbjct: 61 LQLSHNGAYLDLEATLAEQRDELEGFQDDAGRGKKHSIILRTQLSVRVHACIEKLYNSSG 120
Query: 133 PELRRSLFSLKQIFQEDKDLVPEFVHSEGLSCLIRVGAAADHNYQSYILRALGQLMLFVD 192
+LRR+LFSLKQIFQ+DKDLV EFV +EGL+CLI+VGA AD NYQ+YILRALGQ+ML+VD
Sbjct: 121 RDLRRALFSLKQIFQDDKDLVHEFVVAEGLTCLIKVGAEADQNYQNYILRALGQIMLYVD 180
Query: 193 GMLGVVAHSDTIQWLYTLCASLSRLVVKTALKLLLVFVEYSENNAPLFIRAVNSVASTTG 252
GM GV+ ++TIQWLYTL S RLVVKTALKLLLVFVEYSE+NAPL I+AV +V + G
Sbjct: 181 GMNGVINRNETIQWLYTLIGSKFRLVVKTALKLLLVFVEYSESNAPLLIQAVTAVDTKRG 240
Query: 253 APPWANLVSILEEKNGADPELLVYTVTLINKTLAALPDQDSFYDVTDALEQQGMEALVQR 312
PW+N++ ILEEK+G D ELLVY +TL+NKTL+ LPDQD+FYDV D LE+ G+ A+ QR
Sbjct: 241 VKPWSNIMEILEEKDGVDTELLVYAMTLVNKTLSGLPDQDTFYDVVDCLEELGIAAVSQR 300
Query: 313 HLGTAGTDVDLRTQLVLYENALKLEDGDIEEAPGAGGRRERRKPS-------SEEGKRSR 365
HL GTD+DL QL +YE AL+ EDGD P G R+RR+ S G R
Sbjct: 301 HLNKKGTDLDLVEQLNIYEVALRHEDGDETTEPPPSGCRDRRRASVCSSGGGEHRGLDRR 360
Query: 366 RSLEGGGCPARAPEPGPTGPASPVGPTSSTGPALLTGPASSPVG--------PPSGLQAS 417
RS ++ PT P S P+ S G P SG +S
Sbjct: 361 RSRRHSVQSIKSTLSAPTSPCSQSAPSFKPNQVRDLREKYSNFGNNSYHSSRPSSG--SS 418
Query: 418 VNLFPTISVAPSADTSSERS 437
V PT SV+P + ERS
Sbjct: 419 VPTTPTSSVSPPQEARLERS 438
>gi|32880208 diaphanous homolog 3 isoform b [Homo sapiens]
Length = 849
Score = 139 bits (350), Expect = 2e-32
Identities = 113/480 (23%), Positives = 218/480 (45%), Gaps = 48/480 (10%)
Query: 572 PSPPLPLLSGVPPPPPLPPPPPI-------KGPFPPPPPL--------PLAAPLPHSVPD 616
P PPLP GVPPPPP PPPPP+ GP PPPPPL P LP +
Sbjct: 314 PPPPLPSGGGVPPPPPPPPPPPLPGMRMPFSGPVPPPPPLGFLGGQNSPPLPILPFGLKP 373
Query: 617 SSALPTKRKTVKLFWRELKLAGGHGVSASRFGPCATLWASLDPVSVDT----ARLEHLF- 671
+ +L W +++ H ++ + F W ++ + +LE+ F
Sbjct: 374 KKEFKPEISMRRLNWLKIR---PHEMTENCF------WIKVNENKYENVDLLCKLENTFC 424
Query: 672 ----ESRAKEVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTL-PPVHVIKAALLNFDEF 726
E R +E + KK+ + + LD K + ++I L++ P I+ +L DE
Sbjct: 425 CQQKERREEEDIEEKKSIKKKIKELKFLDSKIAQNLSIFLSSFRVPYEEIRMMILEVDET 484
Query: 727 AVSKDGIEKLLTMMPTEEERQKIEEAQLANPDIPLGPAENFLMTLASIGGLAARLQLWAF 786
+++ I+ L+ +P +E+ + +Q + L E F++ ++++ L RL F
Sbjct: 485 RLAESMIQNLIKHLPDQEQLNSL--SQFKSEYSNLCEPEQFVVVMSNVKRLRPRLSAILF 542
Query: 787 KLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAVGNFLN----GSQSSGFELS 842
KL ++ I + + E++ ++ +F +L +L +GN++N +Q+ GF LS
Sbjct: 543 KLQFEEQVNNIKPDIMAVSTACEEIKKSKSFSKLLELVLLMGNYMNAGSRNAQTFGFNLS 602
Query: 843 YLEKVSEVKDTVRRQSLLHHLCSLVLQTRPESSDLYSEIPALTRCAKVDFEQLTENLGQL 902
L K+ + K ++ +LLH L + + P+ + ++ L + +KV E L +NL Q+
Sbjct: 603 SLCKLKDTKSADQKTTLLHFLVEICEEKYPDILNFVDDLEPLDKASKVSVETLEKNLRQM 662
Query: 903 ERRSRAAEESLRSLAKHE-LAPALRARLTHFLDQCARRVAMLRIVHRRVCNRFHAFLLYL 961
R+ + E+ L + E L +++ F+ + L +H + + + +
Sbjct: 663 GRQLQQLEKELETFPPPEDLHDKFVTKMSRFVISAKEQYETLSKLHENMEKLYQSI---I 719
Query: 962 GYTPQAAREVRIMQFCHTLREFALEY-RTCRERVLQQQQKQATYRERNKTRGRMITETEK 1020
GY ++V + F L F + + +E + ++++A +E+ + + E E+
Sbjct: 720 GYYAIDVKKVSVEDFLTDLNNFRTTFMQAIKENI---KKREAEEKEKRVRIAKELAERER 776
>gi|110225351 diaphanous homolog 3 isoform a [Homo sapiens]
Length = 1193
Score = 139 bits (350), Expect = 2e-32
Identities = 113/480 (23%), Positives = 218/480 (45%), Gaps = 48/480 (10%)
Query: 572 PSPPLPLLSGVPPPPPLPPPPPI-------KGPFPPPPPL--------PLAAPLPHSVPD 616
P PPLP GVPPPPP PPPPP+ GP PPPPPL P LP +
Sbjct: 577 PPPPLPSGGGVPPPPPPPPPPPLPGMRMPFSGPVPPPPPLGFLGGQNSPPLPILPFGLKP 636
Query: 617 SSALPTKRKTVKLFWRELKLAGGHGVSASRFGPCATLWASLDPVSVDT----ARLEHLF- 671
+ +L W +++ H ++ + F W ++ + +LE+ F
Sbjct: 637 KKEFKPEISMRRLNWLKIR---PHEMTENCF------WIKVNENKYENVDLLCKLENTFC 687
Query: 672 ----ESRAKEVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTL-PPVHVIKAALLNFDEF 726
E R +E + KK+ + + LD K + ++I L++ P I+ +L DE
Sbjct: 688 CQQKERREEEDIEEKKSIKKKIKELKFLDSKIAQNLSIFLSSFRVPYEEIRMMILEVDET 747
Query: 727 AVSKDGIEKLLTMMPTEEERQKIEEAQLANPDIPLGPAENFLMTLASIGGLAARLQLWAF 786
+++ I+ L+ +P +E+ + +Q + L E F++ ++++ L RL F
Sbjct: 748 RLAESMIQNLIKHLPDQEQLNSL--SQFKSEYSNLCEPEQFVVVMSNVKRLRPRLSAILF 805
Query: 787 KLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAVGNFLN----GSQSSGFELS 842
KL ++ I + + E++ ++ +F +L +L +GN++N +Q+ GF LS
Sbjct: 806 KLQFEEQVNNIKPDIMAVSTACEEIKKSKSFSKLLELVLLMGNYMNAGSRNAQTFGFNLS 865
Query: 843 YLEKVSEVKDTVRRQSLLHHLCSLVLQTRPESSDLYSEIPALTRCAKVDFEQLTENLGQL 902
L K+ + K ++ +LLH L + + P+ + ++ L + +KV E L +NL Q+
Sbjct: 866 SLCKLKDTKSADQKTTLLHFLVEICEEKYPDILNFVDDLEPLDKASKVSVETLEKNLRQM 925
Query: 903 ERRSRAAEESLRSLAKHE-LAPALRARLTHFLDQCARRVAMLRIVHRRVCNRFHAFLLYL 961
R+ + E+ L + E L +++ F+ + L +H + + + +
Sbjct: 926 GRQLQQLEKELETFPPPEDLHDKFVTKMSRFVISAKEQYETLSKLHENMEKLYQSI---I 982
Query: 962 GYTPQAAREVRIMQFCHTLREFALEY-RTCRERVLQQQQKQATYRERNKTRGRMITETEK 1020
GY ++V + F L F + + +E + ++++A +E+ + + E E+
Sbjct: 983 GYYAIDVKKVSVEDFLTDLNNFRTTFMQAIKENI---KKREAEEKEKRVRIAKELAERER 1039
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 133 bits (335), Expect = 9e-31
Identities = 123/499 (24%), Positives = 217/499 (43%), Gaps = 61/499 (12%)
Query: 569 IPAPSPPLPLLSGVPPPPP--------LPPPPPIKG--------PFP-----PPPP---- 603
IP P PPLP +G+PPPPP PPPPP+ G PFP PPPP
Sbjct: 678 IPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMG 737
Query: 604 LPLAAPLPHSVPDSSALPTKRKTVKLFWRELKLAGGHG---VSASRFGPCATLWASLDPV 660
+P P VP + LP KL+ E++L + V+ C W +
Sbjct: 738 MPPPPPFGFGVPAAPVLPFGLTPKKLYKPEVQLRRPNWSKLVAEDLSQDC--FWTKVKED 795
Query: 661 SVDT----ARLEHLFESRAK--EVLPSKKAGEGRRTM-------TTVLDPKRSNAINIGL 707
+ A+L F ++ K + ++ GE ++++ VLD K + ++I L
Sbjct: 796 RFENNELFAKLTLTFSAQTKTSKAKKDQEGGEEKKSVQKKKVKELKVLDSKTAQNLSIFL 855
Query: 708 TTL-PPVHVIKAALLNFDEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDIPLGPAEN 766
+ P IK +L +E +++ I+ L+ MP E+ + + E + D L +E
Sbjct: 856 GSFRMPYQEIKNVILEVNEAVLTESMIQNLIKQMPEPEQLKMLSELKDEYDD--LAESEQ 913
Query: 767 FLMTLASIGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLA 826
F + + ++ L RL FKL + I + + E+L ++ +F +L L
Sbjct: 914 FGVVMGTVPRLRPRLNAILFKLQFSEQVENIKPEIVSVTAACEELRKSESFSNLLEITLL 973
Query: 827 VGNFLN-GSQSS---GFELSYLEKVSEVKDTVRRQSLLHHLCSLVLQTRPESSDLYSEIP 882
VGN++N GS+++ GF +S+L K+ + K T ++ +LLH L L P+ E+
Sbjct: 974 VGNYMNAGSRNAGAFGFNISFLCKLRDTKSTDQKMTLLHFLAELCENDYPDVLKFPDELA 1033
Query: 883 ALTRCAKVDFEQLTENLGQLERRSRAAEESLRSL-AKHELAPALRARLTHFLDQCARRVA 941
+ + ++V E L +NL Q++++ E +++ A + ++T F+ +
Sbjct: 1034 HVEKASRVSAENLQKNLDQMKKQISDVERDVQNFPAATDEKDKFVEKMTSFVKDAQEQYN 1093
Query: 942 MLRIVHRRVCNRFHAFLLYLGYTPQAAREVRIMQFCHTLREFALEYRTCRERVLQQQQKQ 1001
LR++H + + Y + P+ ++ EF ++ R LQ ++
Sbjct: 1094 KLRMMHSNMETLYKELGEYFLFDPKKL----------SVEEFFMDLHNFRNMFLQAVKEN 1143
Query: 1002 ATYRERNKTRGRMITETEK 1020
RE + R EK
Sbjct: 1144 QKRRETEEKMRRAKLAKEK 1162
Score = 52.4 bits (124), Expect = 3e-06
Identities = 30/64 (46%), Positives = 35/64 (54%), Gaps = 12/64 (18%)
Query: 570 PAPSPPLPLLSGV--PPPPPLP------PPPPIKGP--FPPPPPLP--LAAPLPHSVPDS 617
P P PP PL GV PP LP PPPP+ G PPPPPLP + P P S+P
Sbjct: 604 PPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGG 663
Query: 618 SALP 621
+A+P
Sbjct: 664 TAIP 667
Score = 48.1 bits (113), Expect = 5e-05
Identities = 33/86 (38%), Positives = 46/86 (53%), Gaps = 18/86 (20%)
Query: 551 EDEDQDM--LNVESVEAGKDIPA-----PSPPLPLLSG--VPPPPP-----LPPPPPIKG 596
ED ++M L+ ++ +P+ P+PPLP SG +PPPP PPPPP
Sbjct: 547 EDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPP-- 604
Query: 597 PFPPPPPLP--LAAPLPHSVPDSSAL 620
P PPPPPLP + P S+P +A+
Sbjct: 605 PPPPPPPLPGGVCISSPPSLPGGTAI 630
Score = 40.4 bits (93), Expect = 0.010
Identities = 25/64 (39%), Positives = 33/64 (51%), Gaps = 15/64 (23%)
Query: 571 APSPPLPLLSGVPPPPPLPPPPPIKGP----------FPPPPPLPLAA---PLPHSVPDS 617
+P PPL + +PPPPPL P + P PPPPPLP +A P P +P S
Sbjct: 631 SPPPPLSGDATIPPPPPL--PEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGS 688
Query: 618 SALP 621
+ +P
Sbjct: 689 AGIP 692
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 133 bits (335), Expect = 9e-31
Identities = 123/499 (24%), Positives = 217/499 (43%), Gaps = 61/499 (12%)
Query: 569 IPAPSPPLPLLSGVPPPPP--------LPPPPPIKG--------PFP-----PPPP---- 603
IP P PPLP +G+PPPPP PPPPP+ G PFP PPPP
Sbjct: 687 IPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMG 746
Query: 604 LPLAAPLPHSVPDSSALPTKRKTVKLFWRELKLAGGHG---VSASRFGPCATLWASLDPV 660
+P P VP + LP KL+ E++L + V+ C W +
Sbjct: 747 MPPPPPFGFGVPAAPVLPFGLTPKKLYKPEVQLRRPNWSKLVAEDLSQDC--FWTKVKED 804
Query: 661 SVDT----ARLEHLFESRAK--EVLPSKKAGEGRRTM-------TTVLDPKRSNAINIGL 707
+ A+L F ++ K + ++ GE ++++ VLD K + ++I L
Sbjct: 805 RFENNELFAKLTLTFSAQTKTSKAKKDQEGGEEKKSVQKKKVKELKVLDSKTAQNLSIFL 864
Query: 708 TTL-PPVHVIKAALLNFDEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDIPLGPAEN 766
+ P IK +L +E +++ I+ L+ MP E+ + + E + D L +E
Sbjct: 865 GSFRMPYQEIKNVILEVNEAVLTESMIQNLIKQMPEPEQLKMLSELKDEYDD--LAESEQ 922
Query: 767 FLMTLASIGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLA 826
F + + ++ L RL FKL + I + + E+L ++ +F +L L
Sbjct: 923 FGVVMGTVPRLRPRLNAILFKLQFSEQVENIKPEIVSVTAACEELRKSESFSNLLEITLL 982
Query: 827 VGNFLN-GSQSS---GFELSYLEKVSEVKDTVRRQSLLHHLCSLVLQTRPESSDLYSEIP 882
VGN++N GS+++ GF +S+L K+ + K T ++ +LLH L L P+ E+
Sbjct: 983 VGNYMNAGSRNAGAFGFNISFLCKLRDTKSTDQKMTLLHFLAELCENDYPDVLKFPDELA 1042
Query: 883 ALTRCAKVDFEQLTENLGQLERRSRAAEESLRSL-AKHELAPALRARLTHFLDQCARRVA 941
+ + ++V E L +NL Q++++ E +++ A + ++T F+ +
Sbjct: 1043 HVEKASRVSAENLQKNLDQMKKQISDVERDVQNFPAATDEKDKFVEKMTSFVKDAQEQYN 1102
Query: 942 MLRIVHRRVCNRFHAFLLYLGYTPQAAREVRIMQFCHTLREFALEYRTCRERVLQQQQKQ 1001
LR++H + + Y + P+ ++ EF ++ R LQ ++
Sbjct: 1103 KLRMMHSNMETLYKELGEYFLFDPKKL----------SVEEFFMDLHNFRNMFLQAVKEN 1152
Query: 1002 ATYRERNKTRGRMITETEK 1020
RE + R EK
Sbjct: 1153 QKRRETEEKMRRAKLAKEK 1171
Score = 52.4 bits (124), Expect = 3e-06
Identities = 30/64 (46%), Positives = 35/64 (54%), Gaps = 12/64 (18%)
Query: 570 PAPSPPLPLLSGV--PPPPPLP------PPPPIKGP--FPPPPPLP--LAAPLPHSVPDS 617
P P PP PL GV PP LP PPPP+ G PPPPPLP + P P S+P
Sbjct: 613 PPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGG 672
Query: 618 SALP 621
+A+P
Sbjct: 673 TAIP 676
Score = 48.1 bits (113), Expect = 5e-05
Identities = 33/86 (38%), Positives = 46/86 (53%), Gaps = 18/86 (20%)
Query: 551 EDEDQDM--LNVESVEAGKDIPA-----PSPPLPLLSG--VPPPPP-----LPPPPPIKG 596
ED ++M L+ ++ +P+ P+PPLP SG +PPPP PPPPP
Sbjct: 556 EDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPP-- 613
Query: 597 PFPPPPPLP--LAAPLPHSVPDSSAL 620
P PPPPPLP + P S+P +A+
Sbjct: 614 PPPPPPPLPGGVCISSPPSLPGGTAI 639
Score = 40.4 bits (93), Expect = 0.010
Identities = 25/64 (39%), Positives = 33/64 (51%), Gaps = 15/64 (23%)
Query: 571 APSPPLPLLSGVPPPPPLPPPPPIKGP----------FPPPPPLPLAA---PLPHSVPDS 617
+P PPL + +PPPPPL P + P PPPPPLP +A P P +P S
Sbjct: 640 SPPPPLSGDATIPPPPPL--PEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGS 697
Query: 618 SALP 621
+ +P
Sbjct: 698 AGIP 701
>gi|40548415 dishevelled associated activator of morphogenesis 2
[Homo sapiens]
Length = 1067
Score = 129 bits (323), Expect = 2e-29
Identities = 110/375 (29%), Positives = 179/375 (47%), Gaps = 33/375 (8%)
Query: 558 LNVESVEAGKDIPAPSPPLPLLSGVPPPPPLPPPPPIKGPFPP--PPPLPLAAPLPHSVP 615
L + S D+P P PPLP PPPP PP PP P PP PP L + PLP
Sbjct: 529 LTLSSSMTTNDLPPPPPPLPF--ACCPPPPPPPLPPGGPPTPPGAPPCLGMGLPLPQDPY 586
Query: 616 DSSALPTKRKTVKLFWRELKLAGGHGVSASRFGPCATLWASLDPVSV-------DTARLE 668
SS +P ++K V LK ++ R T+W +D + V D ++
Sbjct: 587 PSSDVPLRKKRVPQPSHPLKSFNWVKLNEERVP--GTVWNEIDDMQVFRILDLEDFEKMF 644
Query: 669 HLFESRAKEV-------LPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLP-PVHVIKAAL 720
++ KE+ L S+K E +V+D +R+ I L+ L I+ A+
Sbjct: 645 SAYQRHQKELGSTEDIYLASRKVKE-----LSVIDGRRAQNCIILLSKLKLSNEEIRQAI 699
Query: 721 LNFDEFA-VSKDGIEKLLTMMPTEEERQKIEEAQLANPDIPLGPAENFLMTLASIGGLAA 779
L DE ++KD +E+LL +P + + +EE + + + A+ FL ++ I
Sbjct: 700 LKMDEQEDLAKDMLEQLLKFIPEKSDIDLLEEHK--HEIERMARADRFLYEMSRIDHYQQ 757
Query: 780 RLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAVGNFLNGSQ---S 836
RLQ FK + E + + + +LV++ R +L +LA+GNF+N Q +
Sbjct: 758 RLQALFFKKKFQERLAEAKPKVEAILLASRELVRSKRLRQMLEVILAIGNFMNKGQRGGA 817
Query: 837 SGFELSYLEKVSEVKDTVRRQ-SLLHHLCSLVLQTRPESSDLYSEIPALTRCAKVDFEQL 895
GF ++ L K+++ K ++ R SLLH+L ++ + P+ ++ SE+ L AKV+ +L
Sbjct: 818 YGFRVASLNKIADTKSSIDRNISLLHYLIMILEKHFPDILNMPSELQHLPEAAKVNLAEL 877
Query: 896 TENLGQLERRSRAAE 910
+ +G L R RA E
Sbjct: 878 EKEVGNLRRGLRAVE 892
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 119 bits (298), Expect = 2e-26
Identities = 176/781 (22%), Positives = 283/781 (36%), Gaps = 159/781 (20%)
Query: 292 DSFYDVTDALEQQGMEALVQRHLGTAGTDVDLRTQLVLYENALKLEDGDIEEAPGAGGRR 351
D+ +DV LE + V H+ V L T+ +L D + E
Sbjct: 379 DNIFDVGALLEDTETKNAVLEHMEELQEQVALLTE--------RLRDAENESMAKIAELE 430
Query: 352 ERRKPSSEEGKRSRRSLEGG---GCPARAPEPGPTGPASPVGPTSSTGPA---------- 398
++ + +E + R G R PEP PA+P P++
Sbjct: 431 KQLSQARKELETLRERFSESTAMGASRRPPEPEKAPPAAPTRPSALELKVEELEEKGLIR 490
Query: 399 LLTGPASSPVGPPSGLQASVNLFPTISVAPSADTSSERSIYKARFLENVAAAETEKQVAL 458
+L GP + S+ + P PS
Sbjct: 491 ILRGPGDA---------VSIEILPVAVATPSG---------------------------- 513
Query: 459 AQGRAETLAGAMPNEAGGHPDARQLWDSPETAPAARTPQSPAPCVLLRAQRSLAPEPKEP 518
G A T P G P SP+ APAA AP P P P
Sbjct: 514 --GDAPT-----PGVPTGSP-------SPDLAPAAEPAPGAAP----------PPPPPLP 549
Query: 519 LIPASPKAEPIWELPTRAPRLSIGDLDFSDLGEDEDQDMLNVESVEAGKDIPAPSPPLPL 578
+P+ +A P P +AP L G P P+PPLP
Sbjct: 550 GLPSPQEAPP--SAPPQAPPLP-------------------------GSPEPPPAPPLP- 581
Query: 579 LSGVPPPPPLPPPPP--IKGPFPPPPPLPLAAPLPHSVPDS-----SALPTKRKTVKLFW 631
G PPPP PPPPP GP PPPPP P P P PD+ S L K K
Sbjct: 582 --GDLPPPPPPPPPPPGTDGPVPPPPPPP--PPPPGGPPDALGRRDSELGPGVKAKKPIQ 637
Query: 632 RELKLAGGHGVSASRFGPCATLWASLDPVSV----DTARLEHLFESRAK------EVLPS 681
+ ++ + V+ T++ L+ V D + E F+++++ L S
Sbjct: 638 TKFRMPLLNWVALKPSQITGTVFTELNDEKVLQELDMSDFEEQFKTKSQGPSLDLSALKS 697
Query: 682 KKAGEGRRTMTTVLDPKRSN-AINIGLTTLPPVHVIKAALLNFDEFAVSKDGIEKLLTMM 740
K A + T + + N AI + L + + A+ +D A+ D +E L+ +
Sbjct: 698 KAAQKAPSKATLIEANRAKNLAITLRKGNLGAERICQ-AIEAYDLQALGLDFLELLMRFL 756
Query: 741 PTEEERQKIEEAQL-ANPDIPLGPAENFLMTLASIGGLAARLQLWAFKLDYDSMEREIAE 799
PTE ER I + P L + F++ + I L R+ F ++ + +
Sbjct: 757 PTEYERSLITRFEREQRPMEELSEEDRFMLCFSRIPRLPERMTTLTFLGNFPDTAQLLMP 816
Query: 800 PLFDLKVGMEQLVQNATFRCILATLLAVGNFLNGSQ---SSGFELSYLEKVSEVKDTVRR 856
L + + + R IL +LA GN++N S+ + GF L L+ + E+K T R+
Sbjct: 817 QLNAIIAASMSIKSSDKLRQILEIVLAFGNYMNSSKRGAAYGFRLQSLDALLEMKSTDRK 876
Query: 857 QSLLHHLCSLVLQTRPESSDLYSEIPALTRCAKVDFEQLTENLGQLERRSRAAEESLRSL 916
Q+LLH+L ++ + P+ + +S++ L + V + + ++ L+ R E + R
Sbjct: 877 QTLLHYLVKVIAEKYPQLTGFHSDLHFLDKAGSVSLDSVLADVRSLQ---RGLELTQREF 933
Query: 917 AKHELAPALRARLTHFLDQCARRVAMLRIVHRRVCNRFHAFLLYLGYTPQAAREVRIMQF 976
+ + L+ FL + + L + F + + Y G P+ F
Sbjct: 934 VRQDDCMVLK----EFLRANSPTMDKLLADSKTAQEAFESVVEYFGENPKTTSP---GLF 986
Query: 977 CHTLREFALEYRTCRERVLQQQQKQATYRERNKTRGRMITETEKFSGVAGEAPSNPSVPV 1036
F Y+ + V Q +++ A T G+ GE P+ S P
Sbjct: 987 FSLFSRFIKAYKKAEQEVEQWKKEAAAQEAGADTPGK------------GEPPAPKSPPK 1034
Query: 1037 A 1037
A
Sbjct: 1035 A 1035
>gi|21071077 dishevelled-associated activator of morphogenesis 1
[Homo sapiens]
Length = 1078
Score = 117 bits (292), Expect = 8e-26
Identities = 105/374 (28%), Positives = 177/374 (47%), Gaps = 35/374 (9%)
Query: 566 GKDIPAPSPPLPLLSGVPPPPPLPPPPPIKGPFPPPPPLPLAAPL-PHSVPDSSALPTKR 624
G +P P PP PL G+ PPPP PP P GP PPP P PL A + P P AL K+
Sbjct: 546 GSLLPPPPPP-PLPGGMLPPPP--PPLPPGGPPPPPGPPPLGAIMPPPGAPMGLAL--KK 600
Query: 625 KTVKLFWRELKLAGGHGVSASRFGPCATLWASLDPVSV----DTARLEHLF--------- 671
K++ LK + ++ T+W +D V D LE F
Sbjct: 601 KSIPQPTNALKSFNWSKLPENKLE--GTVWTEIDDTKVFKILDLEDLERTFSAYQRQQDF 658
Query: 672 ----ESRAKE--VLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH-VIKAALLNFD 724
S+ KE + + + + +V+D +R+ NI L+ L + IK A+L D
Sbjct: 659 FVNSNSKQKEADAIDDTLSSKLKVKELSVIDGRRAQNCNILLSRLKLSNDEIKRAILTMD 718
Query: 725 EFA-VSKDGIEKLLTMMPTEEERQKIEEAQLANPDIPLGPAENFLMTLASIGGLAARLQL 783
E + KD +E+LL +P + + +EE + + + A+ FL ++ I RLQ
Sbjct: 719 EQEDLPKDMLEQLLKFVPEKSDIDLLEEHK--HELDRMAKADRFLFEMSRINHYQQRLQS 776
Query: 784 WAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAVGNFLNGSQ---SSGFE 840
FK + E+ + ++ G E++ ++ + +L +LA GN++N Q + GF+
Sbjct: 777 LYFKKKFAERVAEVKPKVEAIRSGSEEVFRSGALKQLLEVVLAFGNYMNKGQRGNAYGFK 836
Query: 841 LSYLEKVSEVKDTVRRQ-SLLHHLCSLVLQTRPESSDLYSEIPALTRCAKVDFEQLTENL 899
+S L K+++ K ++ + +LLH+L ++V P +L E+ + + AKV+ +L + +
Sbjct: 837 ISSLNKIADTKSSIDKNITLLHYLITIVENKYPSVLNLNEELRDIPQAAKVNMTELDKEI 896
Query: 900 GQLERRSRAAEESL 913
L +A E L
Sbjct: 897 STLRSGLKAVETEL 910
>gi|6382071 diaphanous 2 isoform 12C [Homo sapiens]
Length = 1096
Score = 112 bits (281), Expect = 2e-24
Identities = 126/521 (24%), Positives = 217/521 (41%), Gaps = 75/521 (14%)
Query: 543 DLDFSDLGEDEDQDMLNVESVEAGKDIPAPSPPLPLLSGV-PPPPPL-----------PP 590
D +L + Q + + + IP P P P L GV PPPPP PP
Sbjct: 522 DEKIKELEAEIQQLRTQAQVLSSSSGIPGP-PAAPPLPGVGPPPPPPAPPLPGGAPLPPP 580
Query: 591 PPPIKG----PFPPPPPLPLAAPLP----HSVPD----SSALPTKRKTVKLFWRELKLAG 638
PPP+ G P PPPPPL P P VP S LP K K++ E
Sbjct: 581 PPPLPGMMGIPPPPPPPLLFGGPPPPPPLGGVPPPPGISLNLPYGMKQKKMYKPE----- 635
Query: 639 GHGVSASRFGPCATLWASLDPVSVDT------------------ARLEHLFESRAK---- 676
VS R W+ ++P + A+L F ++ K
Sbjct: 636 ---VSMKRIN-----WSKIEPTELSENCFWLRVKEDKFENPDLFAKLALNFATQIKVQKN 687
Query: 677 -EVLPSKKAGEGRRTM--TTVLDPKRSNAINIGLTTL-PPVHVIKAALLNFDEFAVSKDG 732
E L KK G ++ + +LDPK + ++I L + P I+ +L +E +S+
Sbjct: 688 AEALEEKKTGPTKKKVKELRILDPKTAQNLSIFLGSYRMPYEDIRNVILEVNEDMLSEAL 747
Query: 733 IEKLLTMMPTEEERQKIEEAQLANPDIPLGPAENFLMTLASIGGLAARLQLWAFKLDYDS 792
I+ L+ +P E++ E A+L N L E F + ++S+ L RL FKL ++
Sbjct: 748 IQNLVKHLP--EQKILNELAELKNEYDDLCEPEQFGVVMSSVKMLQPRLSSILFKLTFEE 805
Query: 793 MEREIAEPLFDLKVGMEQLVQNATFRCILATLLAVGNFLN----GSQSSGFELSYLEKVS 848
I + + + E+L ++ +F +L +L VGN++N +QS GF++++L K+
Sbjct: 806 HINNIKPSIIAVTLACEELKKSESFNRLLELVLLVGNYMNSGSRNAQSLGFKINFLCKIR 865
Query: 849 EVKDTVRRQSLLHHLCSLVLQTRPESSDLYSEIPALTRCAKVDFEQLTENLGQLERRSRA 908
+ K ++ +LLH + + + + E+ + +KV + L NL +E++
Sbjct: 866 DTKSADQKTTLLHFIADICEEKYRDILKFPEELEHVESASKVSAQILKSNLASMEQQIVH 925
Query: 909 AEESLRSLAKHE-LAPALRARLTHFLDQCARRVAMLRIVHRRVCNRFHAFLLYLGYTPQA 967
E ++ + E ++T F + L +H + + Y +
Sbjct: 926 LERDIKKFPQAENQHDKFVEKMTSFTKTAREQYEKLSTMHNNMMKLYENLGEYFIFD--- 982
Query: 968 AREVRIMQFCHTLREF-ALEYRTCRERVLQQQQKQATYRER 1007
++ V I +F L F L RE +++ ++ T R +
Sbjct: 983 SKTVSIEEFFGDLNNFRTLFLEAVRENNKRREMEEKTRRAK 1023
>gi|5803003 diaphanous 2 isoform 156 [Homo sapiens]
Length = 1101
Score = 112 bits (281), Expect = 2e-24
Identities = 126/521 (24%), Positives = 217/521 (41%), Gaps = 75/521 (14%)
Query: 543 DLDFSDLGEDEDQDMLNVESVEAGKDIPAPSPPLPLLSGV-PPPPPL-----------PP 590
D +L + Q + + + IP P P P L GV PPPPP PP
Sbjct: 522 DEKIKELEAEIQQLRTQAQVLSSSSGIPGP-PAAPPLPGVGPPPPPPAPPLPGGAPLPPP 580
Query: 591 PPPIKG----PFPPPPPLPLAAPLP----HSVPD----SSALPTKRKTVKLFWRELKLAG 638
PPP+ G P PPPPPL P P VP S LP K K++ E
Sbjct: 581 PPPLPGMMGIPPPPPPPLLFGGPPPPPPLGGVPPPPGISLNLPYGMKQKKMYKPE----- 635
Query: 639 GHGVSASRFGPCATLWASLDPVSVDT------------------ARLEHLFESRAK---- 676
VS R W+ ++P + A+L F ++ K
Sbjct: 636 ---VSMKRIN-----WSKIEPTELSENCFWLRVKEDKFENPDLFAKLALNFATQIKVQKN 687
Query: 677 -EVLPSKKAGEGRRTM--TTVLDPKRSNAINIGLTTL-PPVHVIKAALLNFDEFAVSKDG 732
E L KK G ++ + +LDPK + ++I L + P I+ +L +E +S+
Sbjct: 688 AEALEEKKTGPTKKKVKELRILDPKTAQNLSIFLGSYRMPYEDIRNVILEVNEDMLSEAL 747
Query: 733 IEKLLTMMPTEEERQKIEEAQLANPDIPLGPAENFLMTLASIGGLAARLQLWAFKLDYDS 792
I+ L+ +P E++ E A+L N L E F + ++S+ L RL FKL ++
Sbjct: 748 IQNLVKHLP--EQKILNELAELKNEYDDLCEPEQFGVVMSSVKMLQPRLSSILFKLTFEE 805
Query: 793 MEREIAEPLFDLKVGMEQLVQNATFRCILATLLAVGNFLN----GSQSSGFELSYLEKVS 848
I + + + E+L ++ +F +L +L VGN++N +QS GF++++L K+
Sbjct: 806 HINNIKPSIIAVTLACEELKKSESFNRLLELVLLVGNYMNSGSRNAQSLGFKINFLCKIR 865
Query: 849 EVKDTVRRQSLLHHLCSLVLQTRPESSDLYSEIPALTRCAKVDFEQLTENLGQLERRSRA 908
+ K ++ +LLH + + + + E+ + +KV + L NL +E++
Sbjct: 866 DTKSADQKTTLLHFIADICEEKYRDILKFPEELEHVESASKVSAQILKSNLASMEQQIVH 925
Query: 909 AEESLRSLAKHE-LAPALRARLTHFLDQCARRVAMLRIVHRRVCNRFHAFLLYLGYTPQA 967
E ++ + E ++T F + L +H + + Y +
Sbjct: 926 LERDIKKFPQAENQHDKFVEKMTSFTKTAREQYEKLSTMHNNMMKLYENLGEYFIFD--- 982
Query: 968 AREVRIMQFCHTLREF-ALEYRTCRERVLQQQQKQATYRER 1007
++ V I +F L F L RE +++ ++ T R +
Sbjct: 983 SKTVSIEEFFGDLNNFRTLFLEAVRENNKRREMEEKTRRAK 1023
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 112 bits (280), Expect = 2e-24
Identities = 120/508 (23%), Positives = 208/508 (40%), Gaps = 63/508 (12%)
Query: 570 PAPSPPLPLLSGVPPPPPLPPPPPIK---------GPFPPPPPLPLAAPLPHSV------ 614
P P PPLP S PPPP PPPPP+ GP P PPP LA P P +
Sbjct: 684 PPPPPPLPPPSSAGPPPP-PPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLGS 742
Query: 615 -----PDSSALPTKRKTVKLFWRELKLAGGHGVSASRFGPCATLWASLDPVSV-DTARLE 668
P A+ L+W ++ +S TLW SL+ + D + E
Sbjct: 743 SSSQCPRKPAIEPSCPMKPLYWTRIQ------ISDRSQNATPTLWDSLEEPDIRDPSEFE 796
Query: 669 HLF-----ESRAKEVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLP-PVHVIKAALLN 722
+LF + + K + + + + + +LD KRS + I +++L + I+ A+ N
Sbjct: 797 YLFSKDTTQQKKKPLSETYEKKNKVKKIIKLLDGKRSQTVGILISSLHLEMKDIQQAIFN 856
Query: 723 FDEFAVSKDGIEKLLTMMPTEEERQKI-------EEAQLANPDIPLGPAENFLMTLASIG 775
D+ V + + L E+E KI +E +L D P E FL LA I
Sbjct: 857 VDDSVVDLETLAALYENRAQEDELVKIRKYYETSKEEELKLLDKP----EQFLHELAQIP 912
Query: 776 GLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAVGNFLNG-- 833
A R Q F+ + + + + + L+ + + ILA +LA GN++NG
Sbjct: 913 NFAERAQCIIFRSVFSEGITSLHRKVEIITRASKDLLHVKSVKDILALILAFGNYMNGGN 972
Query: 834 ---SQSSGFELSYLEKVSEVKDTVRRQSLLHHLCSLVLQTRPESSDLYSEIPALTR---- 886
Q+ G+ L L K+ +VK +L+ ++ L+ + + + L
Sbjct: 973 RTRGQADGYSLEILPKLKDVKSRDNGINLVDYVVKYYLRYYDQEAGTEKSVFPLPEPQDF 1032
Query: 887 --CAKVDFEQLTENLGQLERRSRAAEESLRSLAKH---ELAPALRARLTHFLDQCARRVA 941
++V FE L ++L +L+R+ A+E+ + + K E + +L F + +
Sbjct: 1033 FLASQVKFEDLIKDLRKLKRQLEASEKQMVVVCKESPKEYLQPFKDKLEEFFQKAKKEHK 1092
Query: 942 MLRIVHRRVCNRFHAFLLYLGYTPQAA-REVRIMQFCHTLREFALEYRTCRERV---LQQ 997
M F + Y G P++ +E+ EF +++T +R + +
Sbjct: 1093 MEESHLENAQKSFETTVRYFGMKPKSGEKEITPSYVFMVWYEFCSDFKTIWKRESKNISK 1152
Query: 998 QQKQATYRERNKTRGRMITETEKFSGVA 1025
++ + +K ET+K + A
Sbjct: 1153 ERLKMAQESVSKLTSEKKVETKKINPTA 1180
>gi|52485606 formin-like 2 [Homo sapiens]
Length = 1092
Score = 108 bits (271), Expect = 2e-23
Identities = 99/387 (25%), Positives = 163/387 (42%), Gaps = 55/387 (14%)
Query: 569 IPAPSPPLPLLSG-------------VPPPPPLPPPPPIKGPFPPPPPLP-------LAA 608
+P P PPLP S +PPPPP PPPPP P PPPPPLP A
Sbjct: 526 LPPPPPPLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPPLPGPAAETVPAP 585
Query: 609 PLPHSVPDSSALPTKRKTVKLFWRELKLAGGHGVSASRFGPCATLWASLDPVSV------ 662
PL +P + LP +F L ++F W +L P +
Sbjct: 586 PLAPPLPSAPPLPGTSSPTVVFNSGLAAVKIKKPIKTKFRMPVFNWVALKPNQINGTVFN 645
Query: 663 ---DTARLEHLFESRAKEVLPSKKAG-------------EGRRTMTTVLDPKRSNAINIG 706
D LE L +E+ +K G + T+L+ R+ + I
Sbjct: 646 EIDDERILEDLNVDEFEEIFKTKAQGPAIDLSSSKQKIPQKGSNKVTLLEANRAKNLAIT 705
Query: 707 LTTL-PPVHVIKAALLNFDEFAVSKDGIEKLLTMMPTEEERQKI-----EEAQLANPDIP 760
L I A+ FD + D +E L+ +PTE E + + E L N
Sbjct: 706 LRKAGKTADEICKAIHVFDLKTLPVDFVECLMRFLPTENEVKVLRLYERERKPLEN---- 761
Query: 761 LGPAENFLMTLASIGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCI 820
L + F+M + I L ++ + AF ++ + + L + + + + I
Sbjct: 762 LSDEDRFMMQFSKIERLMQKMTIMAFIGNFAESIQMLTPQLHAIIAASVSIKSSQKLKKI 821
Query: 821 LATLLAVGNFLNGSQSS---GFELSYLEKVSEVKDTVRRQSLLHHLCSLVLQTRPESSDL 877
L +LA+GN++N S+ GF+L L+ + + K T R+Q+LLH++ ++V + + S
Sbjct: 822 LEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKQTLLHYISNVVKEKYHQVSLF 881
Query: 878 YSEIPALTRCAKVDFEQLTENLGQLER 904
Y+E+ + + A V E + ++ +L+R
Sbjct: 882 YNELHYVEKAAAVSLENVLLDVKELQR 908
>gi|119120861 formin-like 3 isoform 2 [Homo sapiens]
Length = 976
Score = 107 bits (267), Expect = 7e-23
Identities = 111/455 (24%), Positives = 209/455 (45%), Gaps = 35/455 (7%)
Query: 568 DIPAPSPPLPLLSGVPPPP--PL-PPPPPIKGPFPPPPPLPLAAPLPHSVPDSSALPTKR 624
D+ AP+PP + +PPPP PL PPPPP+ PP PPLP AAP SA+ K
Sbjct: 453 DLLAPAPPPEEVLPLPPPPAPPLPPPPPPLPDKCPPAPPLPGAAPSVVLTVGLSAIRIK- 511
Query: 625 KTVKLFWRELKLAGGHGVSASRFGPCATLWASLDPVSV----DTARLEHLFESRAK---- 676
K +K +R L + + ++ T+++ LD + D + E LF+++A+
Sbjct: 512 KPIKTKFR-LPVFNWTALKPNQIS--GTVFSELDDEKILEDLDLDKFEELFKTKAQGPAL 568
Query: 677 EVLPSK-KAGEGRRTMTTVLDPKRSNAINIGLTTL-PPVHVIKAALLNFDEFAVSKDGIE 734
+++ SK K + + T+L+ R+ + I L I A+ FD + D +E
Sbjct: 569 DLICSKNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEEICRAIHTFDLQTLPVDFVE 628
Query: 735 KLLTMMPTEEERQKIEEAQL-ANPDIPLGPAENFLMTLASIGGLAARLQLWAFKLDYDSM 793
L+ +PTE E + + + + P L + F++ + + L R+ AF ++
Sbjct: 629 CLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDN 688
Query: 794 EREIAEPLFDLKVGMEQLVQNATFRCILATLLAVGNFLNGSQSS---GFELSYLEKVSEV 850
+ + L + + + + +L +LA+GN++N S+ GF+L L+ + +
Sbjct: 689 LQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKRGAVYGFKLQSLDLLLDT 748
Query: 851 KDTVRRQSLLHHLCSLVLQTRPESSDLYSEIPALTRCAKVDFEQLTENLGQLERRSRAAE 910
K T R+ +LLH + V + P+ ++ + E+ + + A V E + ++ +L R E
Sbjct: 749 KSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVSLENVLLDVKEL---GRGME 805
Query: 911 ESLRSLAKHELAPALRARLTHFLDQCARRVAMLRIVHRRVCNRFHAFLLYLGYTPQAA-R 969
R + H+ + L +FL ++ L+ + ++A + Y G +P+
Sbjct: 806 LIRRECSIHD-----NSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPKTTPP 860
Query: 970 EVRIMQFCHTLREF-----ALEYRTCRERVLQQQQ 999
V F +R + E R +E V++++Q
Sbjct: 861 SVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQ 895
>gi|119120874 formin-like 3 isoform 1 [Homo sapiens]
Length = 1027
Score = 107 bits (267), Expect = 7e-23
Identities = 111/455 (24%), Positives = 209/455 (45%), Gaps = 35/455 (7%)
Query: 568 DIPAPSPPLPLLSGVPPPP--PL-PPPPPIKGPFPPPPPLPLAAPLPHSVPDSSALPTKR 624
D+ AP+PP + +PPPP PL PPPPP+ PP PPLP AAP SA+ K
Sbjct: 504 DLLAPAPPPEEVLPLPPPPAPPLPPPPPPLPDKCPPAPPLPGAAPSVVLTVGLSAIRIK- 562
Query: 625 KTVKLFWRELKLAGGHGVSASRFGPCATLWASLDPVSV----DTARLEHLFESRAK---- 676
K +K +R L + + ++ T+++ LD + D + E LF+++A+
Sbjct: 563 KPIKTKFR-LPVFNWTALKPNQIS--GTVFSELDDEKILEDLDLDKFEELFKTKAQGPAL 619
Query: 677 EVLPSK-KAGEGRRTMTTVLDPKRSNAINIGLTTL-PPVHVIKAALLNFDEFAVSKDGIE 734
+++ SK K + + T+L+ R+ + I L I A+ FD + D +E
Sbjct: 620 DLICSKNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEEICRAIHTFDLQTLPVDFVE 679
Query: 735 KLLTMMPTEEERQKIEEAQL-ANPDIPLGPAENFLMTLASIGGLAARLQLWAFKLDYDSM 793
L+ +PTE E + + + + P L + F++ + + L R+ AF ++
Sbjct: 680 CLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDN 739
Query: 794 EREIAEPLFDLKVGMEQLVQNATFRCILATLLAVGNFLNGSQSS---GFELSYLEKVSEV 850
+ + L + + + + +L +LA+GN++N S+ GF+L L+ + +
Sbjct: 740 LQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKRGAVYGFKLQSLDLLLDT 799
Query: 851 KDTVRRQSLLHHLCSLVLQTRPESSDLYSEIPALTRCAKVDFEQLTENLGQLERRSRAAE 910
K T R+ +LLH + V + P+ ++ + E+ + + A V E + ++ +L R E
Sbjct: 800 KSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVSLENVLLDVKEL---GRGME 856
Query: 911 ESLRSLAKHELAPALRARLTHFLDQCARRVAMLRIVHRRVCNRFHAFLLYLGYTPQAA-R 969
R + H+ + L +FL ++ L+ + ++A + Y G +P+
Sbjct: 857 LIRRECSIHD-----NSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPKTTPP 911
Query: 970 EVRIMQFCHTLREF-----ALEYRTCRERVLQQQQ 999
V F +R + E R +E V++++Q
Sbjct: 912 SVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQ 946
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 102 bits (255), Expect = 2e-21
Identities = 106/408 (25%), Positives = 169/408 (41%), Gaps = 71/408 (17%)
Query: 566 GKDIPAPSPPLPLLSGVPPPPPLP-------PPPPIKGP---FPPPPPLPLAAPLPHSVP 615
G IP P PPLP +G+PPPPPLP P PP+ P PPPP LP++ P
Sbjct: 1192 GVGIPPP-PPLPG-AGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQV 1249
Query: 616 DSSALPTK---------------------------------RKTVKLFWRELKLAGGHGV 642
SS LPT R L+W ++L
Sbjct: 1250 GSSTLPTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRPMKPLYWTRIQLHSKRDS 1309
Query: 643 SASRFGPCATLWASLDPVSVDTARLEHLFESRA----KEVLPSKKAGEGRRTMTTVLDPK 698
S S +W ++ S+D E LF A K+ + + + + +L K
Sbjct: 1310 STS------LIWEKIEEPSIDCHEFEELFSKTAVKERKKPISDTISKTKAKQVVKLLSNK 1363
Query: 699 RSNAINIGLTTLP-PVHVIKAALLNFDEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANP 757
RS A+ I +++L + I+ A++N D V + ++ L +E +KIE+ ++
Sbjct: 1364 RSQAVGILMSSLHLDMKDIQHAVVNLDNSVVDLETLQALYENRAQSDELEKIEKHGRSSK 1423
Query: 758 DIP----LGPAENFLMTLASIGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQ 813
D L E FL L+ I + R+ F+ + I L L+ E L
Sbjct: 1424 DKENAKSLDKPEQFLYELSLIPNFSERVFCILFQSTFSESICSIRRKLELLQKLCETLKN 1483
Query: 814 NATFRCILATLLAVGNFLNGS-----QSSGFELSYLEKVSEVKDTVRRQSLLHHLCSLVL 868
+L +LA GN++NG Q+ GF L L K+ +VK + +SLL ++ S L
Sbjct: 1484 GPGVMQVLGLVLAFGNYMNGGNKTRGQADGFGLDILPKLKDVKSSDNSRSLLSYIVSYYL 1543
Query: 869 QTRPESSDL------YSEIPALTRCAKVDFEQLTENLGQLERRSRAAE 910
+ E + E L + +++ FE ++L +L++ +A E
Sbjct: 1544 RNFDEDAGKEQCLFPLPEPQDLFQASQMKFEDFQKDLRKLKKDLKACE 1591
Score = 57.8 bits (138), Expect = 6e-08
Identities = 104/399 (26%), Positives = 147/399 (36%), Gaps = 77/399 (19%)
Query: 259 LVSILEEKNGADPELLVYTVTLINKTLAALPDQDSFYDVTDALEQQGMEALVQRHLGTAG 318
+V + E + L T+ + +A L Q D A QG+E V TA
Sbjct: 664 VVDMKSEGQATVIQQLEQTIEDLRTKIAELERQYPALDTEVASGHQGLENGV-----TAS 718
Query: 319 TDVDLRTQLVLYENALKLEDGDIEEAPGAGGRRERRKPSSEEGKRSRRSLEGGGCPARAP 378
DV L AL+LE+ ++ + + P+ E G + ++G P R P
Sbjct: 719 GDVCLE--------ALRLEEKEVRHHRILEAKSIQTSPTEEGGVLTLPPVDG--LPGRPP 768
Query: 379 EPGPTGPASPVGPTSS--TGPALLTGPA---------------SSPVGPPSGL----QAS 417
P P + GP + + +L+ P S P PPS L Q
Sbjct: 769 CP----PGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQ 824
Query: 418 VNLFPTISVAPSADTSSERSIYKARFLENVAAAETEKQVALAQGRAETLAGAMPNEAGGH 477
P S++ TS E S+ A +N + + + + +MP
Sbjct: 825 PGSQPPHSISTEFQTSHEHSVSSA--FKNSCNIPSPPPLPCTES-----SSSMPGLGMVP 877
Query: 478 PDARQLWD-SPETAPAARTPQSPAPCVLLRAQRSLAPEPKEPLIPASPKAEPIWELPTRA 536
P L + T P+ PQ P L+ L P P P +P + +P
Sbjct: 878 PPPPPLPGMTVPTLPSTAIPQPPP----LQGTEMLPPPP--PPLPGAG-------IPPPP 924
Query: 537 PRLSIGDLDFSDL---GEDEDQDMLNVESVEA----GKDIPAPSPPLPLLSGVPPPPPLP 589
P G L L G + G IP P PPLP +G+PPPPPLP
Sbjct: 925 PLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLP-PPLPG-AGIPPPPPLP 982
Query: 590 -----PPPPIKGP-FPPPPPLPLAA-PLPHSVPDSSALP 621
PPPP+ G PPPPPLP A P P +P + P
Sbjct: 983 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1021
Score = 55.8 bits (133), Expect = 2e-07
Identities = 33/63 (52%), Positives = 38/63 (60%), Gaps = 9/63 (14%)
Query: 566 GKDIPAPSPPLPLLSGVPPPPPLP-----PPPPIKGP-FPPPPPLPLAA-PLPHSVPDSS 618
G IP P PPLP +G+PPPPPLP PPPP+ G PPPPPLP A P P +P +
Sbjct: 972 GAGIPPP-PPLPG-AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1029
Query: 619 ALP 621
P
Sbjct: 1030 IPP 1032
Score = 55.8 bits (133), Expect = 2e-07
Identities = 33/63 (52%), Positives = 38/63 (60%), Gaps = 9/63 (14%)
Query: 566 GKDIPAPSPPLPLLSGVPPPPPLP-----PPPPIKGP-FPPPPPLPLAA-PLPHSVPDSS 618
G IP P PPLP +G+PPPPPLP PPPP+ G PPPPPLP A P P +P +
Sbjct: 983 GAGIPPP-PPLPG-AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1040
Query: 619 ALP 621
P
Sbjct: 1041 IPP 1043
Score = 55.8 bits (133), Expect = 2e-07
Identities = 33/63 (52%), Positives = 38/63 (60%), Gaps = 9/63 (14%)
Query: 566 GKDIPAPSPPLPLLSGVPPPPPLP-----PPPPIKGP-FPPPPPLPLAA-PLPHSVPDSS 618
G IP P PPLP +G+PPPPPLP PPPP+ G PPPPPLP A P P +P +
Sbjct: 994 GAGIPPP-PPLPG-AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1051
Query: 619 ALP 621
P
Sbjct: 1052 IPP 1054
Score = 55.8 bits (133), Expect = 2e-07
Identities = 33/63 (52%), Positives = 38/63 (60%), Gaps = 9/63 (14%)
Query: 566 GKDIPAPSPPLPLLSGVPPPPPLP-----PPPPIKGP-FPPPPPLPLAA-PLPHSVPDSS 618
G IP P PPLP +G+PPPPPLP PPPP+ G PPPPPLP A P P +P +
Sbjct: 1005 GAGIPPP-PPLPG-AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1062
Query: 619 ALP 621
P
Sbjct: 1063 IPP 1065
Score = 55.8 bits (133), Expect = 2e-07
Identities = 33/63 (52%), Positives = 38/63 (60%), Gaps = 9/63 (14%)
Query: 566 GKDIPAPSPPLPLLSGVPPPPPLP-----PPPPIKGP-FPPPPPLPLAA-PLPHSVPDSS 618
G IP P PPLP +G+PPPPPLP PPPP+ G PPPPPLP A P P +P +
Sbjct: 1016 GAGIPPP-PPLPG-AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1073
Query: 619 ALP 621
P
Sbjct: 1074 IPP 1076
Score = 55.8 bits (133), Expect = 2e-07
Identities = 33/63 (52%), Positives = 38/63 (60%), Gaps = 9/63 (14%)
Query: 566 GKDIPAPSPPLPLLSGVPPPPPLP-----PPPPIKGP-FPPPPPLPLAA-PLPHSVPDSS 618
G IP P PPLP +G+PPPPPLP PPPP+ G PPPPPLP A P P +P +
Sbjct: 1027 GAGIPPP-PPLPG-AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1084
Query: 619 ALP 621
P
Sbjct: 1085 IPP 1087
Score = 55.8 bits (133), Expect = 2e-07
Identities = 33/63 (52%), Positives = 38/63 (60%), Gaps = 9/63 (14%)
Query: 566 GKDIPAPSPPLPLLSGVPPPPPLP-----PPPPIKGP-FPPPPPLPLAA-PLPHSVPDSS 618
G IP P PPLP +G+PPPPPLP PPPP+ G PPPPPLP A P P +P +
Sbjct: 1038 GAGIPPP-PPLPG-AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1095
Query: 619 ALP 621
P
Sbjct: 1096 IPP 1098
Score = 55.8 bits (133), Expect = 2e-07
Identities = 32/63 (50%), Positives = 38/63 (60%), Gaps = 9/63 (14%)
Query: 566 GKDIPAPSPPLPLLSGVPPPPPL-----PPPPPIKGP-FPPPPPLP-LAAPLPHSVPDSS 618
G IP P PPLP +G+PPPPPL PPPPP+ G PPPPPLP + P P +P +
Sbjct: 1060 GAGIPPP-PPLPG-AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAG 1117
Query: 619 ALP 621
P
Sbjct: 1118 IPP 1120
Score = 55.8 bits (133), Expect = 2e-07
Identities = 33/63 (52%), Positives = 38/63 (60%), Gaps = 9/63 (14%)
Query: 566 GKDIPAPSPPLPLLSGVPPPPPL-----PPPPPIKGP-FPPPPPLPLAA-PLPHSVPDSS 618
G IP P PPLP +G+PPPPPL PPPPP+ G PPPPPLP A P P +P +
Sbjct: 1082 GAGIPPP-PPLPG-AGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1139
Query: 619 ALP 621
P
Sbjct: 1140 IPP 1142
Score = 55.5 bits (132), Expect = 3e-07
Identities = 33/63 (52%), Positives = 38/63 (60%), Gaps = 9/63 (14%)
Query: 566 GKDIPAPSPPLPLLSGVPPPPPLP-----PPPPIKGP-FPPPPPLPLAA-PLPHSVPDSS 618
G IP P PPLP +G+PPPPPLP PPPP+ G PPPPPLP A P P +P +
Sbjct: 1071 GAGIPPP-PPLPG-AGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAG 1128
Query: 619 ALP 621
P
Sbjct: 1129 IPP 1131
Score = 55.5 bits (132), Expect = 3e-07
Identities = 32/63 (50%), Positives = 38/63 (60%), Gaps = 9/63 (14%)
Query: 566 GKDIPAPSPPLPLLSGVPPPPPL-----PPPPPIKGP-FPPPPPLP-LAAPLPHSVPDSS 618
G IP P PPLP +G+PPPPPL PPPPP+ G PPPPPLP + P P +P +
Sbjct: 1104 GVGIPPP-PPLPG-AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAG 1161
Query: 619 ALP 621
P
Sbjct: 1162 IPP 1164
Score = 55.5 bits (132), Expect = 3e-07
Identities = 31/57 (54%), Positives = 36/57 (63%), Gaps = 9/57 (15%)
Query: 566 GKDIPAPSPPLPLLSGVPPPPPL-----PPPPPIKGP-FPPPPPLP-LAAPLPHSVP 615
G IP P PPLP + G+PPPPPL PPPPP+ G PPPPPLP + P P +P
Sbjct: 1137 GAGIPPP-PPLPRV-GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLP 1191
Score = 54.7 bits (130), Expect = 5e-07
Identities = 33/63 (52%), Positives = 37/63 (58%), Gaps = 9/63 (14%)
Query: 566 GKDIPAPSPPLPLLSGVPPPPPL-----PPPPPIKG-PFPPPPPLPLAA-PLPHSVPDSS 618
G IP P PPLP +G+PPPPPL PPPPP+ G PPPPPLP A P P +P
Sbjct: 1159 GAGIPPP-PPLPG-AGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMG 1216
Query: 619 ALP 621
P
Sbjct: 1217 IPP 1219
Score = 53.1 bits (126), Expect = 1e-06
Identities = 32/63 (50%), Positives = 38/63 (60%), Gaps = 9/63 (14%)
Query: 566 GKDIPAPSPPLPLLSGVPPPPPLP-----PPPPI-KGPFPPPPPLPLAA-PLPHSVPDSS 618
G IP P PPLP +G+PPPPPLP PPPP+ + PPPPPLP A P P +P +
Sbjct: 1115 GAGIPPP-PPLPG-AGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAG 1172
Query: 619 ALP 621
P
Sbjct: 1173 IPP 1175
Score = 51.6 bits (122), Expect = 4e-06
Identities = 35/68 (51%), Positives = 39/68 (57%), Gaps = 14/68 (20%)
Query: 566 GKDIPAPSPPLPLLSGVPPPPPL-----PPPPPIKGP-FPPPPPLPLAA-----PLPH-S 613
G IP P PPLP + G+PPPPPL PPPPP+ G PPPPPLP A PLP
Sbjct: 1093 GAGIPPP-PPLPGV-GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVG 1150
Query: 614 VPDSSALP 621
+P LP
Sbjct: 1151 IPPPPPLP 1158
Score = 31.2 bits (69), Expect = 6.0
Identities = 41/174 (23%), Positives = 59/174 (33%), Gaps = 18/174 (10%)
Query: 374 PARAPEPGPTGPAS------PVGPTSSTGPALLTGPASSPVGPPSGLQASVNLFPTISVA 427
P PG GPA P+ T G +S SG + F + +
Sbjct: 138 PFEVTGPGGPGPAEARVGGRPIAEDVETAAGAQDGQRTS-----SGSDTDIYSFHSATEQ 192
Query: 428 PSADTSSERSIYKARFLENVAAAETEKQVALAQGRAETLAGAMPNEAGGHPDARQLWDSP 487
+ +++I + + + ++Q Q + A P P A D
Sbjct: 193 EDLLSDIQQAIRLQQQQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDRF 252
Query: 488 ETAP---AARTPQSP----APCVLLRAQRSLAPEPKEPLIPASPKAEPIWELPT 534
P A P SP A L SLA EP+EP P SP P+ E P+
Sbjct: 253 LLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPS 306
Score = 30.8 bits (68), Expect = 7.8
Identities = 17/46 (36%), Positives = 18/46 (39%)
Query: 576 LPLLSGVPPPPPLPPPPPIKGPFPPPPPLPLAAPLPHSVPDSSALP 621
LP P P PP P P P LP A P P S+A P
Sbjct: 279 LPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFP 324
Score = 30.8 bits (68), Expect = 7.8
Identities = 19/59 (32%), Positives = 22/59 (37%)
Query: 368 LEGGGCPARAPEPGPTGPASPVGPTSSTGPALLTGPASSPVGPPSGLQASVNLFPTISV 426
L G G P P PG P +P P G + P GPP Q + PT V
Sbjct: 1201 LPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQV 1259
>gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]
Length = 1240
Score = 99.8 bits (247), Expect = 1e-20
Identities = 175/734 (23%), Positives = 293/734 (39%), Gaps = 127/734 (17%)
Query: 445 ENVAAAETEKQVALAQGRAETLAGAMPNEAGGHPDARQLWDSPETAPAARTPQSPAPCVL 504
E V A++E + ++Q RA + P P L P P P P V
Sbjct: 395 EPVDHAQSESILKVSQPRALEQQASTPPP----PPPPPLLPGSSAEPPPPPPPPPLPSVG 450
Query: 505 LRAQRSLAPEPKEPLIPA-SPKAEPIWELPTRAPRLSIGDLDFSDLGEDEDQDMLNVESV 563
+A + P P P + A +P A P LP P G +F
Sbjct: 451 AKALPTAPPPPPLPGLGAMAPPAPP---LPPPLP----GSCEF----------------- 486
Query: 564 EAGKDIPAPSPPLPLLSGVPPPPPLPPPPPIKGPFPPPPPLP--------------LAAP 609
+P P PPLP L PPPPPL P P PPPP LP + A
Sbjct: 487 -----LPPPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPLLPCTCSPPVAGGMEEVIVAQ 541
Query: 610 LPHSVPDSSALPTKRKT-------VKLFWREL--KLAGGHGVSASRFGPCATLWASL--- 657
+ H + S+ +P+ R+ KL W++L +A H ++WASL
Sbjct: 542 VDHGL-GSAWVPSHRRVNPPTLRMKKLNWQKLPSNVAREHN----------SMWASLSSP 590
Query: 658 --DPVSVDTARLEHLFE-SRAKEVLPSKKAGEGRR--TMTTVLDPKRSNAINIGLTTLPP 712
+ V D + +E LF AK P+ A R+ T LD K+S +NI L
Sbjct: 591 DAEAVEPDFSSIERLFSFPAAKPKEPTMVAPRARKEPKEITFLDAKKSLNLNIFLKQFKC 650
Query: 713 VHVIKAALLNFDEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPD-IPLGPAENFLMTL 771
+ AA++ + +K +E L ++ E+ +IE + + L A++F + L
Sbjct: 651 SNEEVAAMIRAGD--TTKFDVEVLKQLLKLLPEKHEIENLRAFTEERAKLASADHFYLLL 708
Query: 772 ASIGGLAARLQLWAFKLDYDSMEREIAEPLFDLKV-GMEQLVQNATFRCILATLLAVGNF 830
+I R++ + + ++ P L + E L+ + +L +GNF
Sbjct: 709 LAIPCYQLRIECMLL-CEGAAAVLDMVRPKAQLVLAACESLLTSRQLPIFCQLILRIGNF 767
Query: 831 LN-GS---QSSGFELSYLEKVSEVKDTVRRQSLLHHLCSLVLQTRPESSDLYSEIPALTR 886
LN GS + GF++S L K++E K R +LLHH+ ++ P+ L ++ ++
Sbjct: 768 LNYGSHTGDADGFKISTLLKLTETKSQQNRVTLLHHVLEEAEKSHPDLLQLPRDLEQPSQ 827
Query: 887 CAKVDFE----QLTENLGQLERRSRAAEESLRSLAKHELAPALRARLTHF--LDQCARRV 940
A ++ E + + NL +L R S+ + + + L+A ++ F LD+ +
Sbjct: 828 AAGINLEIIRSEASSNLKKLLETERKVSASVAEV-QEQYTERLQASISAFRALDELFEAI 886
Query: 941 AMLRIVHRRVCNRFHAFLLYLGYTPQAAREVRIMQFCHTLREFA-LEYRTCRERVLQQQQ 999
+ R + + Y + A+++ + T++ F L R +E + ++
Sbjct: 887 EQKQ---RELAD----------YLCEDAQQLSLEDTFSTMKAFRDLFLRALKEN--KDRK 931
Query: 1000 KQATYRERNKTRGRMITETEKFSGVAGEAPSNPSVPVAVSSGPGRGDADSHASMKSLLTS 1059
+QA ER K + + E E A P V GPG+ + + +LL
Sbjct: 932 EQAAKAERRK---QQLAEEE-----ARRPRGEDGKP--VRKGPGK--QEEVCVIDALLAD 979
Query: 1060 RPEDTTHNRRSRGMVQSSSPIMPTVGPSTASPEEPPGSSLPSDTSDEIMDLLVQSVTKSS 1119
+ + +RG T G S A+ +PP ++ P TS+ D + + +S
Sbjct: 980 IRKGFQLRKTARGRGD-------TDGGSKAASMDPPRATEPVATSNPAGDPVGSTRCPAS 1032
Query: 1120 PRALAARERKRSRG 1133
L A SRG
Sbjct: 1033 EPGLDATTASESRG 1046
>gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]
Length = 1249
Score = 99.8 bits (247), Expect = 1e-20
Identities = 175/734 (23%), Positives = 293/734 (39%), Gaps = 127/734 (17%)
Query: 445 ENVAAAETEKQVALAQGRAETLAGAMPNEAGGHPDARQLWDSPETAPAARTPQSPAPCVL 504
E V A++E + ++Q RA + P P L P P P P V
Sbjct: 395 EPVDHAQSESILKVSQPRALEQQASTPPP----PPPPPLLPGSSAEPPPPPPPPPLPSVG 450
Query: 505 LRAQRSLAPEPKEPLIPA-SPKAEPIWELPTRAPRLSIGDLDFSDLGEDEDQDMLNVESV 563
+A + P P P + A +P A P LP P G +F
Sbjct: 451 AKALPTAPPPPPLPGLGAMAPPAPP---LPPPLP----GSCEF----------------- 486
Query: 564 EAGKDIPAPSPPLPLLSGVPPPPPLPPPPPIKGPFPPPPPLP--------------LAAP 609
+P P PPLP L PPPPPL P P PPPP LP + A
Sbjct: 487 -----LPPPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPLLPCTCSPPVAGGMEEVIVAQ 541
Query: 610 LPHSVPDSSALPTKRKT-------VKLFWREL--KLAGGHGVSASRFGPCATLWASL--- 657
+ H + S+ +P+ R+ KL W++L +A H ++WASL
Sbjct: 542 VDHGL-GSAWVPSHRRVNPPTLRMKKLNWQKLPSNVAREHN----------SMWASLSSP 590
Query: 658 --DPVSVDTARLEHLFE-SRAKEVLPSKKAGEGRR--TMTTVLDPKRSNAINIGLTTLPP 712
+ V D + +E LF AK P+ A R+ T LD K+S +NI L
Sbjct: 591 DAEAVEPDFSSIERLFSFPAAKPKEPTMVAPRARKEPKEITFLDAKKSLNLNIFLKQFKC 650
Query: 713 VHVIKAALLNFDEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPD-IPLGPAENFLMTL 771
+ AA++ + +K +E L ++ E+ +IE + + L A++F + L
Sbjct: 651 SNEEVAAMIRAGD--TTKFDVEVLKQLLKLLPEKHEIENLRAFTEERAKLASADHFYLLL 708
Query: 772 ASIGGLAARLQLWAFKLDYDSMEREIAEPLFDLKV-GMEQLVQNATFRCILATLLAVGNF 830
+I R++ + + ++ P L + E L+ + +L +GNF
Sbjct: 709 LAIPCYQLRIECMLL-CEGAAAVLDMVRPKAQLVLAACESLLTSRQLPIFCQLILRIGNF 767
Query: 831 LN-GS---QSSGFELSYLEKVSEVKDTVRRQSLLHHLCSLVLQTRPESSDLYSEIPALTR 886
LN GS + GF++S L K++E K R +LLHH+ ++ P+ L ++ ++
Sbjct: 768 LNYGSHTGDADGFKISTLLKLTETKSQQNRVTLLHHVLEEAEKSHPDLLQLPRDLEQPSQ 827
Query: 887 CAKVDFE----QLTENLGQLERRSRAAEESLRSLAKHELAPALRARLTHF--LDQCARRV 940
A ++ E + + NL +L R S+ + + + L+A ++ F LD+ +
Sbjct: 828 AAGINLEIIRSEASSNLKKLLETERKVSASVAEV-QEQYTERLQASISAFRALDELFEAI 886
Query: 941 AMLRIVHRRVCNRFHAFLLYLGYTPQAAREVRIMQFCHTLREFA-LEYRTCRERVLQQQQ 999
+ R + + Y + A+++ + T++ F L R +E + ++
Sbjct: 887 EQKQ---RELAD----------YLCEDAQQLSLEDTFSTMKAFRDLFLRALKEN--KDRK 931
Query: 1000 KQATYRERNKTRGRMITETEKFSGVAGEAPSNPSVPVAVSSGPGRGDADSHASMKSLLTS 1059
+QA ER K + + E E A P V GPG+ + + +LL
Sbjct: 932 EQAAKAERRK---QQLAEEE-----ARRPRGEDGKP--VRKGPGK--QEEVCVIDALLAD 979
Query: 1060 RPEDTTHNRRSRGMVQSSSPIMPTVGPSTASPEEPPGSSLPSDTSDEIMDLLVQSVTKSS 1119
+ + +RG T G S A+ +PP ++ P TS+ D + + +S
Sbjct: 980 IRKGFQLRKTARGRGD-------TDGGSKAASMDPPRATEPVATSNPAGDPVGSTRCPAS 1032
Query: 1120 PRALAARERKRSRG 1133
L A SRG
Sbjct: 1033 EPGLDATTASESRG 1046
>gi|223278403 glutamate receptor, ionotropic, delta 2 (Grid2)
interacting protein [Homo sapiens]
Length = 1211
Score = 85.5 bits (210), Expect = 3e-16
Identities = 131/577 (22%), Positives = 217/577 (37%), Gaps = 92/577 (15%)
Query: 356 PSSEEGKRSRRSLEGGGCPARAPEPGPTGPASPVGPTSSTGPALLTGPASSPVGPPSGLQ 415
PSS E SL+ P+ P PGP P SP P+ P PPS +
Sbjct: 622 PSSSES-HPYASLDSSRAPSPQPGPGPICPDSP--------------PSPDPTRPPSRRK 666
Query: 416 ASVNLFPTISVAPSADTSSERSIYKARFLENVAAAETEKQVALAQGRAETLAGAMPNEAG 475
LF S DT RFL+ V + + +V + + L E
Sbjct: 667 ----LFTFSHPVRSRDTD--------RFLD-VLSEQLGPRVTIVD---DFLTPENDYEEM 710
Query: 476 GHPDARQLWDSPETAPAARTPQSPAPCVLLRAQRSLAPEPKEPLIPASPKAEPIWELPTR 535
D + + + E + A+ S L P PL P P
Sbjct: 711 SFHDDQGSFVTNERSSASDCISSSEEGSSLTYSSISDHIPPPPLSPPPP----------- 759
Query: 536 APRLSIGDLDFSDLGEDEDQDMLNVESVEAGKDIPAPSPPLPLLSGVPPPPPLPPPPPIK 595
P L D S D G PA + PL P PP PPPPP+
Sbjct: 760 -PPLPFHDAKPSSRSSD-------------GSRGPAQALAKPLTQLSHPVPP-PPPPPLP 804
Query: 596 GPFPPPPPLPLAAPLPHSVPDSSALPTKRKTVKLFWRELKLAGGHGVSASRFGPCATLWA 655
P P PP+ L+ L H ++S + KR L W +++ + G T+W
Sbjct: 805 PPVPCAPPM-LSRGLGHRRSETSHMSVKR----LRWEQVENSEG------------TIWG 847
Query: 656 SL------DPVSVDTARLE---HLFESRAKEVLPSKKAGEGRRTMTTVLDPKRSN-AINI 705
L D +S L+ H + + +P + + + + K N +I +
Sbjct: 848 QLGEDSDYDKLSDMVKYLDLELHFGTQKPAKPVPGPEPFRKKEVVEILSHKKAYNTSILL 907
Query: 706 GLTTLPPVHVIKAALLNFDEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDIPLGPAE 765
L P ++ L++ + + + +LL P +E Q+ + + A L +
Sbjct: 908 AHLKLSPAE-LRQVLMSMEPRRLEPAHLAQLLLFAPDADEEQRYQAFREAPGR--LSEPD 964
Query: 766 NFLMTLASIGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLL 825
F++ + S+ RL+ F+ EI L L+ +L + IL +L
Sbjct: 965 QFVLQMLSVPEYKTRLRSLHFQATLQEKTEEIRGSLECLRQASLELKNSRKLAKILEFVL 1024
Query: 826 AVGNFLNGSQ-----SSGFELSYLEKVSEVKDTVRRQSLLHHLCSLVLQTRPESSDLYSE 880
A+GN+LN Q ++GF++++L +++ K + + LH L + Q PE +
Sbjct: 1025 AMGNYLNDGQPKTNKTTGFKINFLTELNSTKTVDGKSTFLHILAKSLSQHFPELLGFAQD 1084
Query: 881 IPALTRCAKVDFEQLTENLGQLERRSRAAEESLRSLA 917
+P + AKV+ LT +L L +++ +S++
Sbjct: 1085 LPTVPLAAKVNQRALTSDLADLHGTISEIQDACQSIS 1121
>gi|145309324 FH2 domain containing 1 [Homo sapiens]
Length = 1143
Score = 82.8 bits (203), Expect = 2e-15
Identities = 119/572 (20%), Positives = 220/572 (38%), Gaps = 83/572 (14%)
Query: 570 PAPSPPLPLLSGVPPPPPLPP------------PPPIKGPFPPPPPLPLAAPLPHSVPDS 617
P P+PP P PPPPP PP PPP P P PP+P P P +P +
Sbjct: 30 PPPAPPPP----PPPPPPSPPCSCSREECPSSPPPPPPPPLPGEPPIP---PPPPGLPPT 82
Query: 618 ------SALPTKRKTVKLFWRELKLAGGHGVSASRFGPCATLWA----SLDPVSVDTARL 667
S L K++ FW+ + G + +W +DT +
Sbjct: 83 THMNGYSHLGKKKRMRSFFWKTIPEEQVRGKT--------NIWTLAARQEHHYQIDTKTI 134
Query: 668 EHLF---ESRAKEVLPSK-----KAGEGRRTMTTVLDPKRSNAINIGLTTL--PPVHVIK 717
E LF E K LP + + R T+LD KRS I I L P +++
Sbjct: 135 EELFGQQEDTTKSSLPRRGRTLNSSFREAREEITILDAKRSMNIGIFLKQFKKSPRSIVE 194
Query: 718 AALLNFDEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDIPLGPAENFLMTLASIGGL 777
E + + + L +P EE +K++ + L A++FL L +
Sbjct: 195 DIHQGKSEH-YGSETLREFLKFLPESEEVKKLK--AFSGDVSKLSLADSFLYGLIQVPNY 251
Query: 778 AARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAVGNFLN----G 833
+ R++ K ++ + + L+ +++L+ IL +L GN +N
Sbjct: 252 SLRIEAMVLKKEFLPSCSSLYTDITVLRTAIKELMSCEELHSILHLVLQAGNIMNAGGYA 311
Query: 834 SQSSGFELSYLEKVSEVKDTVRRQSLLHHLCSLVLQTRPESSDLYSEIPALTRCAKVDFE 893
+ GF+LS L K+++ K +LLH + + + ++ + + A++ E
Sbjct: 312 GNAVGFKLSSLLKLADTKANKPGMNLLHFVAQEAQKKDTILLNFSEKLHHVQKTARLSLE 371
Query: 894 QLTENLGQLERRSRAAEESLRSLAKHELAPALRARLTHFLDQCARRVAMLRIVHRRVCNR 953
L L R+++ +E+++ + L ++ FL ++ L + + +
Sbjct: 372 NTEAELHLLFVRTKSLKENIQRDGE------LCQQMEDFLQFAIEKLRELECWKQELQDE 425
Query: 954 FHAFLLYLGYTPQAAREVRIMQFCHTLREFALEY---------RTCRERVLQQQQKQATY 1004
+ + + + + +++ + R+F ++ R +E Q+ K+
Sbjct: 426 AYTL---IDFFCEDKKTMKLDECFQIFRDFCTKFNKAVKDNHDREAQELRQLQRLKEQEQ 482
Query: 1005 RERNKTRGRMITETEKFSGVAGEAPSNPSVPVAVSSGPGRGDADSHAS--MKSLLTSRPE 1062
++R+ G + G G + S V + G H S + RP
Sbjct: 483 KQRSWATGEL--------GAFGRSSSENDVELLTKKGAEGLLPFLHPRPISPSSPSYRPP 534
Query: 1063 DTTHNRRSRGMVQSSSPIMPTVGPSTASPEEP 1094
+T +R S G + ++ + ST SPEEP
Sbjct: 535 NTRRSRLSLG-PSADRELLTFLESSTGSPEEP 565
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 75.9 bits (185), Expect = 2e-13
Identities = 77/279 (27%), Positives = 113/279 (40%), Gaps = 49/279 (17%)
Query: 359 EEGKRSRRSLEGGGCPARAPEPG--PTGPASPVGPTSSTGPALLTGPASSPVGPPSGLQA 416
+ GKR + G P +P P+ PA + P PA+ P S G L+A
Sbjct: 1290 KSGKRHPPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEA 1349
Query: 417 SVNLFPTISVAPSADTSSERSIYKARFLENVAAAETEKQVALAQGR--AETLAGAM---- 470
+ + + PS + + R LE + + ++++ ++A+ R E+++ A+
Sbjct: 1350 AESEGLGLG-CPSPCKRLDEEL--KRNLETLPSFSSDEEDSVAKNRDLQESISSAISALD 1406
Query: 471 -PNEAGGHPDARQLWDSPETAPAARTPQSPAPCVLLRAQRSLAPEPK------EPLIPAS 523
P AG P D P APAA P P L A + PEP P P +
Sbjct: 1407 DPPLAG--PKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPA 1464
Query: 524 PKAEPIWELPTRAPRLSIGDLDFSDLGEDEDQDMLNVESVEAGKDIPAPSPPLPLLSGVP 583
P +P P P+ ++ P+P P + P
Sbjct: 1465 PTPQPQPPPPPPPPQPAL----------------------------PSPPPLVAPTPSSP 1496
Query: 584 PPPPLPPPPPIKGPFPPPPPLPLAAPLPHSVPDSSALPT 622
PPPPLPPPPP P PPPPP P AAPL + P+ A P+
Sbjct: 1497 PPPPLPPPPPPAMPSPPPPPPPAAAPLA-APPEEPAAPS 1534
Score = 37.4 bits (85), Expect = 0.084
Identities = 60/226 (26%), Positives = 75/226 (33%), Gaps = 58/226 (25%)
Query: 378 PEPGPTGPASPVGPTSSTGPALLTGPASSPVGP-PSGLQASVNLFPTISVA--PSADTSS 434
P PG TG VGP +S G PA + P P G +A P S+ S
Sbjct: 892 PAPGDTG----VGPPNSEGK----DPAGAYRSPSPQGTKAP-RFVPLTSICFPDSLLQDE 942
Query: 435 ERSIYKARFLENVAAAETEKQVALAQGRAETLAGAMPNEAGGHPDARQLWDSPETAPAAR 494
ERS + + G A+ A P E G P A P P A
Sbjct: 943 ERSFFPTM------------EEMFGGGAADDYGKAGPPEDEGDPKAGA---GPPPGPPAY 987
Query: 495 TPQSPAPCVLLRAQRSLAPEPKEPLIPASPKAEPIWELPTRAPRLSIGDLDFSDLGEDED 554
P P C R+ P+ P + P P ELP+ +G
Sbjct: 988 DPYGPY-C----PGRASGAGPETPGLGLDPNKPP--ELPSTVNAEPLG------------ 1028
Query: 555 QDMLNVESVEAGKDIPAPSPPLPLLSGVPPPPPLPPPPPIKGPFPP 600
+++G AP PP P PPPPP P P G P
Sbjct: 1029 -------LIQSGPHQAAPPPPPP-----PPPPPAPASEPKGGLTSP 1062
Score = 36.6 bits (83), Expect = 0.14
Identities = 26/73 (35%), Positives = 29/73 (39%), Gaps = 27/73 (36%)
Query: 570 PAPSPPLPLLS----------GVPPPPPLPPPPPIKGPFPPPPPLPL-----------AA 608
P+PSP + G P PPP PPPP PPP PL L AA
Sbjct: 810 PSPSPSASKVGVHLLEPATRDGAPQPPPPPPPP------PPPMPLQLEAHLRSHGLEPAA 863
Query: 609 PLPHSVPDSSALP 621
P P P+ S P
Sbjct: 864 PSPRLRPEESLDP 876
Score = 30.8 bits (68), Expect = 7.8
Identities = 22/73 (30%), Positives = 24/73 (32%), Gaps = 8/73 (10%)
Query: 577 PLLSGVPPPPPLPPPPPIKGPFPPPPPLPL--------AAPLPHSVPDSSALPTKRKTVK 628
P SG PP PP PPPP P L P P S LPT ++
Sbjct: 473 PSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLS 532
Query: 629 LFWRELKLAGGHG 641
GHG
Sbjct: 533 YSTGHSPALSGHG 545
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 60.5 bits (145), Expect = 9e-09
Identities = 89/316 (28%), Positives = 113/316 (35%), Gaps = 54/316 (17%)
Query: 340 DIEEAPGAGGRRERRKPSSEEGKRSRRSLEGGGCPARAPEPGPTGPA-SPVGPTSSTGPA 398
DI E PG P S LE P+ AP P P A SP P + + P+
Sbjct: 153 DISEPPGGS---PLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSP--PHTLSSPS 207
Query: 399 LLTGPASSPVGPPSGLQASVNLFPTISVAPSADTSSERSIYKARFLENVAAAETEKQVAL 458
+ T P P PP A P AP+ + R + + VAL
Sbjct: 208 IPTPPDFIPPAPPLAFLAPP---PPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVAL 264
Query: 459 AQGRAETLAGAMPNEAGGHPDARQLWDSPE---TAPAARTPQSPAPC-----VLLRAQRS 510
GR A P + P L +PE T P + P P + AQ +
Sbjct: 265 -NGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEA 323
Query: 511 LAPE-------PKEPLIPASPKAEPIWEL-PTRAPRLSI-GDLDFSD-----LGEDEDQD 556
E P +P S P ++ P RAP G+L + LG+ + Q
Sbjct: 324 PRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQ- 382
Query: 557 MLNVESVEAGKDIPAPSPPLPLLSGVPPPPPLPPPPPIKGPFPP-PPPLPLAAPLPH--- 612
+ P P+PPLP PP PPLPPP P P PP PPLP A H
Sbjct: 383 ------ADERAGTPPPAPPLP-----PPAPPLPPPAP---PLPPAAPPLPCAQKAAHPPA 428
Query: 613 ---SVPDSSALPTKRK 625
P SS+ K K
Sbjct: 429 GFTKTPKSSSPALKPK 444
Score = 30.8 bits (68), Expect = 7.8
Identities = 56/223 (25%), Positives = 81/223 (36%), Gaps = 41/223 (18%)
Query: 323 LRTQLVLYENALKLEDGDIEEAPGAGGRRERRKPSSEEGKRSRRSLEGG---GCPARAPE 379
LR +L Y + ED + PG P S+EGK+ R E PA+
Sbjct: 470 LRNELAAYLCGSRREDRFLSHRPGP-----TVAPQSKEGKKGPRLPEKETLLSLPAKDTP 524
Query: 380 PGPTGPASPVGPTSSTGPALLTGPASSPVGPPSGLQASVNLFPTISVAPSADTSSERSIY 439
PG P S G + LT ++P S SV+ P S PS R+
Sbjct: 525 PGV--------PEKSLGGSSLTETEAAP----SLTLPSVDYIPQDSPTPSV--RQIRNEL 570
Query: 440 KARFLENVAAAETEKQVA-------LAQGR-----------AETLAGAMPNEAGGHPDAR 481
+AR L + A E + + L GR ++ +A +P ++
Sbjct: 571 EAR-LSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTT 629
Query: 482 QLWDSPETAPAARTPQSPAPCVLLRAQRSLAPEPKEPLIPASP 524
L PA +P P + +A A PK L PA+P
Sbjct: 630 SLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATP 672
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 60.5 bits (145), Expect = 9e-09
Identities = 89/316 (28%), Positives = 113/316 (35%), Gaps = 54/316 (17%)
Query: 340 DIEEAPGAGGRRERRKPSSEEGKRSRRSLEGGGCPARAPEPGPTGPA-SPVGPTSSTGPA 398
DI E PG P S LE P+ AP P P A SP P + + P+
Sbjct: 153 DISEPPGGS---PLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSP--PHTLSSPS 207
Query: 399 LLTGPASSPVGPPSGLQASVNLFPTISVAPSADTSSERSIYKARFLENVAAAETEKQVAL 458
+ T P P PP A P AP+ + R + + VAL
Sbjct: 208 IPTPPDFIPPAPPLAFLAPP---PPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVAL 264
Query: 459 AQGRAETLAGAMPNEAGGHPDARQLWDSPE---TAPAARTPQSPAPC-----VLLRAQRS 510
GR A P + P L +PE T P + P P + AQ +
Sbjct: 265 -NGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEA 323
Query: 511 LAPE-------PKEPLIPASPKAEPIWEL-PTRAPRLSI-GDLDFSD-----LGEDEDQD 556
E P +P S P ++ P RAP G+L + LG+ + Q
Sbjct: 324 PRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQ- 382
Query: 557 MLNVESVEAGKDIPAPSPPLPLLSGVPPPPPLPPPPPIKGPFPP-PPPLPLAAPLPH--- 612
+ P P+PPLP PP PPLPPP P P PP PPLP A H
Sbjct: 383 ------ADERAGTPPPAPPLP-----PPAPPLPPPAP---PLPPAAPPLPCAQKAAHPPA 428
Query: 613 ---SVPDSSALPTKRK 625
P SS+ K K
Sbjct: 429 GFTKTPKSSSPALKPK 444
Score = 30.8 bits (68), Expect = 7.8
Identities = 56/223 (25%), Positives = 81/223 (36%), Gaps = 41/223 (18%)
Query: 323 LRTQLVLYENALKLEDGDIEEAPGAGGRRERRKPSSEEGKRSRRSLEGG---GCPARAPE 379
LR +L Y + ED + PG P S+EGK+ R E PA+
Sbjct: 470 LRNELAAYLCGSRREDRFLSHRPGP-----TVAPQSKEGKKGPRLPEKETLLSLPAKDTP 524
Query: 380 PGPTGPASPVGPTSSTGPALLTGPASSPVGPPSGLQASVNLFPTISVAPSADTSSERSIY 439
PG P S G + LT ++P S SV+ P S PS R+
Sbjct: 525 PGV--------PEKSLGGSSLTETEAAP----SLTLPSVDYIPQDSPTPSV--RQIRNEL 570
Query: 440 KARFLENVAAAETEKQVA-------LAQGR-----------AETLAGAMPNEAGGHPDAR 481
+AR L + A E + + L GR ++ +A +P ++
Sbjct: 571 EAR-LSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTT 629
Query: 482 QLWDSPETAPAARTPQSPAPCVLLRAQRSLAPEPKEPLIPASP 524
L PA +P P + +A A PK L PA+P
Sbjct: 630 SLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATP 672
>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
sapiens]
Length = 1188
Score = 60.5 bits (145), Expect = 9e-09
Identities = 89/316 (28%), Positives = 113/316 (35%), Gaps = 54/316 (17%)
Query: 340 DIEEAPGAGGRRERRKPSSEEGKRSRRSLEGGGCPARAPEPGPTGPA-SPVGPTSSTGPA 398
DI E PG P S LE P+ AP P P A SP P + + P+
Sbjct: 153 DISEPPGGS---PLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSP--PHTLSSPS 207
Query: 399 LLTGPASSPVGPPSGLQASVNLFPTISVAPSADTSSERSIYKARFLENVAAAETEKQVAL 458
+ T P P PP A P AP+ + R + + VAL
Sbjct: 208 IPTPPDFIPPAPPLAFLAPP---PPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVAL 264
Query: 459 AQGRAETLAGAMPNEAGGHPDARQLWDSPE---TAPAARTPQSPAPC-----VLLRAQRS 510
GR A P + P L +PE T P + P P + AQ +
Sbjct: 265 -NGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEA 323
Query: 511 LAPE-------PKEPLIPASPKAEPIWEL-PTRAPRLSI-GDLDFSD-----LGEDEDQD 556
E P +P S P ++ P RAP G+L + LG+ + Q
Sbjct: 324 PRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQ- 382
Query: 557 MLNVESVEAGKDIPAPSPPLPLLSGVPPPPPLPPPPPIKGPFPP-PPPLPLAAPLPH--- 612
+ P P+PPLP PP PPLPPP P P PP PPLP A H
Sbjct: 383 ------ADERAGTPPPAPPLP-----PPAPPLPPPAP---PLPPAAPPLPCAQKAAHPPA 428
Query: 613 ---SVPDSSALPTKRK 625
P SS+ K K
Sbjct: 429 GFTKTPKSSSPALKPK 444
Score = 30.8 bits (68), Expect = 7.8
Identities = 56/223 (25%), Positives = 81/223 (36%), Gaps = 41/223 (18%)
Query: 323 LRTQLVLYENALKLEDGDIEEAPGAGGRRERRKPSSEEGKRSRRSLEGG---GCPARAPE 379
LR +L Y + ED + PG P S+EGK+ R E PA+
Sbjct: 470 LRNELAAYLCGSRREDRFLSHRPGP-----TVAPQSKEGKKGPRLPEKETLLSLPAKDTP 524
Query: 380 PGPTGPASPVGPTSSTGPALLTGPASSPVGPPSGLQASVNLFPTISVAPSADTSSERSIY 439
PG P S G + LT ++P S SV+ P S PS R+
Sbjct: 525 PGV--------PEKSLGGSSLTETEAAP----SLTLPSVDYIPQDSPTPSV--RQIRNEL 570
Query: 440 KARFLENVAAAETEKQVA-------LAQGR-----------AETLAGAMPNEAGGHPDAR 481
+AR L + A E + + L GR ++ +A +P ++
Sbjct: 571 EAR-LSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTT 629
Query: 482 QLWDSPETAPAARTPQSPAPCVLLRAQRSLAPEPKEPLIPASP 524
L PA +P P + +A A PK L PA+P
Sbjct: 630 SLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATP 672
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 59.3 bits (142), Expect = 2e-08
Identities = 78/321 (24%), Positives = 106/321 (33%), Gaps = 49/321 (15%)
Query: 342 EEAPGAGGRR-----ERRKPSSEEGKRSRRSLEGGGCPARAPEPGPTGPASPVGPTSSTG 396
E A G GG R P+ G SR PA P G +P +S G
Sbjct: 60 ERAGGIGGATIPESAPRAGPTRSAGTSSRN-------PASRPPASGRGERAPPAKNTSPG 112
Query: 397 PALLTGPASSPVGPPSGLQASVNLFPTISVAPSADTSSERSIYKARFLENVAAAETEKQV 456
P G AS P Q + + +VA T + + + + T
Sbjct: 113 PVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP 172
Query: 457 ALAQGRAETLAGAMPNEAGGHPDARQL---------------WDSPETAPAARTPQSPAP 501
+ A R AG P AR + E +PAAR S
Sbjct: 173 SPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG 232
Query: 502 CVLLRAQRSLAPE-----------------PKEPLIPASPKAEPIWELPTRAPRLSIGDL 544
+ A RSL+ P+ P P+ PK + + L R P+++
Sbjct: 233 GLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQAL--RPPQVTPPRK 290
Query: 545 DFSDLGEDEDQDMLNVESVEAGKDIPAPSPP---LPLLSGVPPPPPLPPPPPIKGPFPPP 601
D + L S K P P P PL + +PP PPL P P+ P P
Sbjct: 291 DAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSA 350
Query: 602 PPLPLAAPLPHSVPDSSALPT 622
PP P P + P S A P+
Sbjct: 351 PPSLQTLPSPPATPPSQAPPS 371
Score = 57.0 bits (136), Expect = 1e-07
Identities = 75/269 (27%), Positives = 94/269 (34%), Gaps = 59/269 (21%)
Query: 373 CPARAPE-----PGPTGPASPVGPTSSTGPAL-------LTGPASSPVGPPSGLQASVNL 420
CP +AP P P P+S P PAL L P SP+ P
Sbjct: 567 CPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLA 626
Query: 421 FPTISVAPSADTSSERSIYKARFLENVAAAETEKQVALAQGRAETLAGAMPN---EAGGH 477
P + PS S L +A + ALA + P+ +A
Sbjct: 627 LPPLQAPPSPPASPP--------LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS 678
Query: 478 PDARQLWDSPETAPAARTPQSPAPCVLLRAQRSLAPEPKEPLIPASPKAEPIWELPTRAP 537
P A SP +P+A TP S AP L + P P PASP P P +AP
Sbjct: 679 PPA-----SPPVSPSA-TPPSQAPPSLAAPPLQVPPSP-----PASPPMSPSATPPPQAP 727
Query: 538 RLSIGDLDFSDLGEDEDQDMLNVESVEAGKDIPAPSPPLPLLSGVPPP--PPLPPPPPIK 595
L ++ PA P P S PPP PPL PP++
Sbjct: 728 ------------------PPLAAPPLQVPPSPPASPPMSP--SATPPPRVPPLLAAPPLQ 767
Query: 596 GPFPPP---PPLPLAAPLPHSVPDSSALP 621
P PP P PLA P P + P + P
Sbjct: 768 VPPSPPASLPMSPLAKPPPQAPPALATPP 796
Score = 55.8 bits (133), Expect = 2e-07
Identities = 84/312 (26%), Positives = 106/312 (33%), Gaps = 76/312 (24%)
Query: 376 RAPEPGPTGPASPVGPTSSTGPALLTGPASSPVGPPSGLQASVN-----LFPTISVAPSA 430
R + T P+ P + P L P S P PP LQ S++ L +++ P
Sbjct: 435 RQTQASLTSPSRPASTPPDSPP--LQAPLSLPASPP--LQTSLSPAVSPLSSPLTIHPLQ 490
Query: 431 DTSSERSIYKARFLENVAAAETEKQVALAQGRAETLAGAMP-----NEAGGHPDARQLWD 485
SS S L ++ E Q +LA +T ++ N P Q
Sbjct: 491 ALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTAS 550
Query: 486 SPETAPAARTPQSPAPCVLLRAQRSLAPEPKE---------------------------- 517
+P T P TP PAPC L L P E
Sbjct: 551 APLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPP 610
Query: 518 --PLIPASPKAEPIWELPT-RAPRLSIGDLDFSDLGEDEDQ--DMLNVESVEAGKDIPAP 572
PL P+A P LP +AP S L Q + L V ++A P P
Sbjct: 611 LSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS-PPP 669
Query: 573 SPPL----------PLLSGVPPP---------PPL--PPPPPIKGPF------PPPPPLP 605
SPP+ P+ PP PPL PP PP P PP P P
Sbjct: 670 SPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 729
Query: 606 LAAPLPHSVPDS 617
LAAP P VP S
Sbjct: 730 LAAP-PLQVPPS 740
Score = 55.5 bits (132), Expect = 3e-07
Identities = 79/276 (28%), Positives = 104/276 (37%), Gaps = 41/276 (14%)
Query: 374 PARAPEPGPTGPASPVGPTSSTGPALLTGPASSPVGPPSGLQASVNLFPTISVAPSADTS 433
PA P P P+ P S + P L S P PPS S+ P + PS T
Sbjct: 328 PATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTT-PPMQAPPSLQTI 386
Query: 434 SERSIYKARFLENVAAAETEKQVALAQGRAETLAGAMPNEAGGH------PDARQLWDSP 487
I L + + +AL+ +A T G+ P H P Q +
Sbjct: 387 PP--IQVPHSLTSPSLQAPPSPLALSSLQATTSLGS-PTLQATHSFLTMSPRQTQASLTS 443
Query: 488 ETAPAARTPQSPAPCVLLRAQRSLAPEP--KEPLIPA-SPKAEPIWELPTRA-------- 536
+ PA+ P SP L+A SL P + L PA SP + P+ P +A
Sbjct: 444 PSRPASTPPDSPP----LQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHS 499
Query: 537 PRLSIGDLDFSDLGEDEDQDMLNVESVEAGKDIPAPSPPLPLLSGVPPPP------PLPP 590
P+ + L L E Q L S++ +PPL L + PPP PL
Sbjct: 500 PQAPLSSLIMPPL---ETQSSLAPPSLQT-PPASLTTPPLENLPSLAPPPLQTASAPLTT 555
Query: 591 P----PPIKGPFP-PPPPLPLAAPLPHSVPDSSALP 621
P PP P P PP PL P P + P S A P
Sbjct: 556 PHLETPPCPAPCPLQAPPSPLTTPPPET-PSSIATP 590
Score = 51.2 bits (121), Expect = 6e-06
Identities = 74/278 (26%), Positives = 92/278 (33%), Gaps = 70/278 (25%)
Query: 382 PTGPASPVG-PTSSTGPALLTGPASSPVGPPSGLQASVNLFPTISVAPSADTSSERSIYK 440
P+ P SP+ P P L P +P PP AS L P + +P A + + +
Sbjct: 607 PSPPLSPLATPPPQAPPXLALPPLQAPPSPP----ASPPLSPLATPSPQAPNALAVHLLQ 662
Query: 441 ARFLE----------NVAAAETEKQVALAQGRAETLAGAMPNEAGGHPDARQLWDSPETA 490
A F + A+ A +A A P + P A SP +
Sbjct: 663 APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA-----SPPMS 717
Query: 491 PAARTPQSPAPCVLLRAQRSLAPEPKEPLIPASPKAEPIWELPTRAPRLSIGDLDFSDLG 550
P+A TP AP L + P P PASP P P R P L
Sbjct: 718 PSA-TPPPQAPPPLAAPPLQVPPSP-----PASPPMSPSATPPPRVPPL----------- 760
Query: 551 EDEDQDMLNVESVEAGKDIPAPSPPLPLLSGVPPPPP---------LPPPP---PIKGPF 598
L ++ PA P PL P PP LP PP P + PF
Sbjct: 761 -------LAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPF 813
Query: 599 --------------PPPPPLPLAAPLPHSVPDSSALPT 622
PP P LAAPL P A PT
Sbjct: 814 SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 851
Score = 49.3 bits (116), Expect = 2e-05
Identities = 70/262 (26%), Positives = 94/262 (35%), Gaps = 50/262 (19%)
Query: 374 PARAPEPGPTGPASPVGPTSSTGPALLTGPASSPV-GPPSGLQASVNLFPTISVAPSADT 432
P+ AP P T A P T P PA P+ PPS L P+ P
Sbjct: 539 PSLAPPPLQTASAPLTTPHLETPPC----PAPCPLQAPPSPLTTPPPETPSSIATPPPQA 594
Query: 433 SSERSIYKARFLENVAAAETEKQVALAQGRAETLAGAMPNEAGGHPDARQLWDSPETAPA 492
+ + L + + +A +A P +A P A SP +P
Sbjct: 595 PPALASPPLQGLPSPPLSP----LATPPPQAPPXLALPPLQAPPSPPA-----SPPLSPL 645
Query: 493 AR-TPQSPAPCVLLRAQRSLAPEPKEPLI-----PASPKAEPIWELPTRAPRLSIGDLDF 546
A +PQ+P + Q +P P P+ PASP P P++AP
Sbjct: 646 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP--------- 696
Query: 547 SDLGEDEDQDMLNVESVEAGKDIPAPSPPL-PLLSGVPPPPPLPPP----PPIKGPFPPP 601
S+ A PSPP P +S PPP PP PP++ P PP
Sbjct: 697 --------------PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPP 742
Query: 602 --PPLPLAAPLPHSVPDSSALP 621
PP+ +A P VP A P
Sbjct: 743 ASPPMSPSATPPPRVPPLLAAP 764
Score = 42.7 bits (99), Expect = 0.002
Identities = 67/262 (25%), Positives = 87/262 (33%), Gaps = 37/262 (14%)
Query: 378 PEPGPTGPASPVGPTSSTGPA-----LLTGPASSPVGPPSGLQASVNLFPTISVAPSADT 432
P P + P SP+ S P LL P S P PP +QA + + V+PSA
Sbjct: 634 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP--VQAPFSPPASPPVSPSATP 691
Query: 433 SSERSIYKA----RFLENVAAAETEKQVALAQGRAETLAGAMPNEAGGHPDARQLWDSPE 488
S+ A + + A+ A +A A P + P A SP
Sbjct: 692 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPM-SPS 750
Query: 489 TAPAARTPQ---------SPAPCVLLRAQRSLAPEPKEPLIPASPKAE----PIWELPTR 535
P R P P+P L P P+ P A+P + P P +
Sbjct: 751 ATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQ 810
Query: 536 APRLSIGDLDFSDLGEDEDQDMLNVESVEAGK--DIPAPSPPLPLLSGVPPPPPLPPPPP 593
AP L S L Q V A +P P P L PP P
Sbjct: 811 APFSPSASLPMSPLATPPPQ----APPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTS 866
Query: 594 IKGP------FPPPPPLPLAAP 609
+ GP P PPP P +P
Sbjct: 867 VSGPRLTLALAPGPPPPPSRSP 888
Score = 41.2 bits (95), Expect = 0.006
Identities = 59/237 (24%), Positives = 78/237 (32%), Gaps = 26/237 (10%)
Query: 374 PARAP-EPGPTGPASPVG-PTSSTGPALLTGPASSPVGPPSGLQASVNLFPTISVAPSAD 431
P +AP P + P SP P S P+L P P PP AS + P+ + P A
Sbjct: 672 PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP----ASPPMSPSATPPPQAP 727
Query: 432 TSSERSIYKARFLENVAAAETEKQVALAQGRAETLAGAMPNEAGGHPDARQLWDS----- 486
+ + A+ A R L A P + P A
Sbjct: 728 PPLAAPPLQVP--PSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPP 785
Query: 487 PETAPAARTPQS---PAPCVLLRAQRSLAPE---PKEPLIPASPKAEPIWELPTRAPRLS 540
P+ PA TP P+P Q +P P PL P+A P+ AP L
Sbjct: 786 PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV----LAAPLLQ 841
Query: 541 IGDLDFSDLGEDEDQDMLNVESVEAGKDIPAPSPPLPLLSGVPPPPPLPPPPPIKGP 597
+ S Q + + P L L G PPPP P + GP
Sbjct: 842 VPP---SPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 895
Score = 38.5 bits (88), Expect = 0.038
Identities = 60/257 (23%), Positives = 91/257 (35%), Gaps = 45/257 (17%)
Query: 374 PARAPEP--------GPTGPASPVGPTSSTGPA-----LLTGPASSPVGPPSGLQASVNL 420
P +AP P P+ PASP S+T P L P P PP+ L S
Sbjct: 723 PPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLA 782
Query: 421 FPTISVAPSADTSSERSI------YKARFLENVAAAETEKQVALAQGRAETLAGAMPNEA 474
P P+ T +++ + + + +A+ +A +A + A +
Sbjct: 783 KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV 842
Query: 475 GGHPDARQLWDSPETAPAARTPQSPAPCVLLRAQR---SLAPEPKEPLIPASPKAEPIWE 531
P A SP T A R P +P P + R +LAP P P
Sbjct: 843 PPSPPA-----SP-TLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP------------- 883
Query: 532 LPTRAPRLSIGDLDF---SDLGEDEDQDMLNVESVEAGKDIPAPSPPLPLLSGVPPPPPL 588
P+R+P ++ D S +++ +S G +P P L + P
Sbjct: 884 -PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSR 942
Query: 589 PPPPPIKGPFPPPPPLP 605
P PP+ P PLP
Sbjct: 943 GPAPPLAFRGAPGAPLP 959
Score = 33.5 bits (75), Expect = 1.2
Identities = 73/300 (24%), Positives = 93/300 (31%), Gaps = 63/300 (21%)
Query: 339 GDIEEAP-----GAGGRRERR-----KPSSEEGKRSRRSLEGGGCPARAPEPGPTGPAS- 387
G EAP AG RR+ PS +RSR + G P AP P P
Sbjct: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
Query: 388 PVGPTSSTGPALLTGPASSPVGPPS---GLQASVNLFPTISVAPSADTSSERSIYKARFL 444
P SS T P+ + PS GLQ + + S P + S RS AR
Sbjct: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS--SPARSGPSARGT 262
Query: 445 ENVAAAETEKQVALAQGRAETLAGAMPNEAGGHPDARQLWDSPETAPAAR----TPQSPA 500
A ++ + Q A P P L SP P+ P P
Sbjct: 263 PRAPAHPSQPKPKGLQ--ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPP 320
Query: 501 PCVLLRAQRSLAPEPKE----PLIPASPKAEPIWELPTRAPRLSIGDLDFSDLGEDEDQD 556
+L P P PL P SP A P + P
Sbjct: 321 DNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATP---------------- 364
Query: 557 MLNVESVEAGKDIPAPSPPLPLLSGVPPPPPLPPPPPIKGPF--------PPPPPLPLAA 608
P+ +PP + PP L PPI+ P PP PL L++
Sbjct: 365 -------------PSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSS 411
Score = 32.7 bits (73), Expect = 2.1
Identities = 35/123 (28%), Positives = 49/123 (39%), Gaps = 12/123 (9%)
Query: 374 PARAPEPGPTGPASPVGPTSSTGPALLTGPASSPVGPPSGLQASVNLFPTISVAPSADTS 433
P R P PGP TS +GP L A P PPS +S P ++ S+ TS
Sbjct: 855 PRRPPTPGPD--------TSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATS 906
Query: 434 SERSI--YKARFLENVAAA-ETEKQVALAQGRAETLAGAMPNEAGGHPDARQLWDSPETA 490
+ + Y + AA+ + ++A A + A P G P A W P T
Sbjct: 907 TPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPW-PPATG 965
Query: 491 PAA 493
P +
Sbjct: 966 PGS 968
>gi|149944526 additional sex combs like 3 [Homo sapiens]
Length = 2248
Score = 58.5 bits (140), Expect = 4e-08
Identities = 31/64 (48%), Positives = 36/64 (56%), Gaps = 3/64 (4%)
Query: 571 APSPPLPLLSGVPPPPPLPPPPPIKGPFPPPPPLPLAAPLPHS-VPDSSALP--TKRKTV 627
A + P L PPPPP PPPPP+ P PPPPP PL PLP++ VP P T T
Sbjct: 2006 AHTMPNKALVHPPPPPPPPPPPPLALPPPPPPPPPLPPPLPNAEVPSDQKQPPVTMETTK 2065
Query: 628 KLFW 631
+L W
Sbjct: 2066 RLSW 2069
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 58.2 bits (139), Expect = 5e-08
Identities = 27/44 (61%), Positives = 28/44 (63%), Gaps = 2/44 (4%)
Query: 570 PAPSPPLPLLSGVPPPPPLPPPPPIKGPFPPPPPLPLAAPLPHS 613
P P PP PL S PPPPP PPPP+ PPPPP P A PLP S
Sbjct: 334 PGPPPPPPLPSTGPPPPP--PPPPLPNQVPPPPPPPPAPPLPAS 375
Score = 50.4 bits (119), Expect = 1e-05
Identities = 27/58 (46%), Positives = 30/58 (51%), Gaps = 6/58 (10%)
Query: 570 PAPSPPLPLLSGVPPPPPL--PPPPPIKG----PFPPPPPLPLAAPLPHSVPDSSALP 621
P P PP P + V PPP PPPPP+ P PPPPPLP P P P + LP
Sbjct: 316 PPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPPPPAPPLP 373
Score = 43.1 bits (100), Expect = 0.002
Identities = 22/41 (53%), Positives = 22/41 (53%), Gaps = 9/41 (21%)
Query: 583 PPPPPLPPP--------PPIKGPFPPPPPLPLAAPLPHSVP 615
PPPPPLPP PP GP PPPPPLP P P P
Sbjct: 314 PPPPPLPPGPAQASVALPPPPGP-PPPPPLPSTGPPPPPPP 353
Score = 36.6 bits (83), Expect = 0.14
Identities = 17/33 (51%), Positives = 17/33 (51%)
Query: 566 GKDIPAPSPPLPLLSGVPPPPPLPPPPPIKGPF 598
G P P PPLP PPPPP PP P G F
Sbjct: 346 GPPPPPPPPPLPNQVPPPPPPPPAPPLPASGFF 378
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 58.2 bits (139), Expect = 5e-08
Identities = 27/44 (61%), Positives = 28/44 (63%), Gaps = 2/44 (4%)
Query: 570 PAPSPPLPLLSGVPPPPPLPPPPPIKGPFPPPPPLPLAAPLPHS 613
P P PP PL S PPPPP PPPP+ PPPPP P A PLP S
Sbjct: 334 PGPPPPPPLPSTGPPPPP--PPPPLPNQVPPPPPPPPAPPLPAS 375
Score = 50.4 bits (119), Expect = 1e-05
Identities = 27/58 (46%), Positives = 30/58 (51%), Gaps = 6/58 (10%)
Query: 570 PAPSPPLPLLSGVPPPPPL--PPPPPIKG----PFPPPPPLPLAAPLPHSVPDSSALP 621
P P PP P + V PPP PPPPP+ P PPPPPLP P P P + LP
Sbjct: 316 PPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPPPPAPPLP 373
Score = 43.1 bits (100), Expect = 0.002
Identities = 22/41 (53%), Positives = 22/41 (53%), Gaps = 9/41 (21%)
Query: 583 PPPPPLPPP--------PPIKGPFPPPPPLPLAAPLPHSVP 615
PPPPPLPP PP GP PPPPPLP P P P
Sbjct: 314 PPPPPLPPGPAQASVALPPPPGP-PPPPPLPSTGPPPPPPP 353
Score = 36.6 bits (83), Expect = 0.14
Identities = 17/33 (51%), Positives = 17/33 (51%)
Query: 566 GKDIPAPSPPLPLLSGVPPPPPLPPPPPIKGPF 598
G P P PPLP PPPPP PP P G F
Sbjct: 346 GPPPPPPPPPLPNQVPPPPPPPPAPPLPASGFF 378
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 58.2 bits (139), Expect = 5e-08
Identities = 43/151 (28%), Positives = 61/151 (40%), Gaps = 10/151 (6%)
Query: 480 ARQLWDSPETAPAARTPQSPAPCVLLRAQRSLAPEPKEPLIPASPKAEPIWELPTRAP-- 537
+R L D P P P P + A P+ +P +P++P+ + P P
Sbjct: 257 SRALDDKPPPPPP---PVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPP 313
Query: 538 -RLSIGDLDFSDLGEDEDQDMLNVESVEAGKDIPAPSP----PLPLLSGVPPPPPLPPPP 592
R L S G DE + + P PSP PLP PPPP+ PP
Sbjct: 314 SRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPP 373
Query: 593 PIKGPFPPPPPLPLAAPLPHSVPDSSALPTK 623
GP PPPPP+ ++P + LP++
Sbjct: 374 GRSGPLPPPPPVSRNGSTSRALPATPQLPSR 404
Score = 42.4 bits (98), Expect = 0.003
Identities = 62/241 (25%), Positives = 87/241 (36%), Gaps = 31/241 (12%)
Query: 376 RAPEPGPTGPASPVGPTSSTGPALLTGPA-SSPVGPPSGLQASVNLFPTISVA------- 427
R P PGPT P P + G AL G SP+ S L PT S A
Sbjct: 211 RQPSPGPTPPPFP----GNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPP 266
Query: 428 PSADTSSERSIYKARFLENVAAAETEKQVALAQGRAETLAGAMPNEAGGHPDARQLWDSP 487
P + SI++ + + V + + P P L P
Sbjct: 267 PPPPVGNRPSIHREA-VPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPL--PP 323
Query: 488 ETAPAARTPQSPAPCVLLRAQRSLAPEPKEPLIPASPKAEPIWELPTRAPRLSIGDLDFS 547
++ TP+ P QR+L+ P +P+ ++ P+ P+ P + D
Sbjct: 324 SSSGNDETPRLP--------QRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGR 375
Query: 548 DLGEDEDQDMLNVESVEAGKDIPAPSPPLPLLSGVPPP-----PPLPPPPPIKGPFPPPP 602
+ S + +PA +P LP SGV P PPLPP P G PPPP
Sbjct: 376 SGPLPPPPPVSRNGSTS--RALPA-TPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPP 432
Query: 603 P 603
P
Sbjct: 433 P 433
Score = 37.7 bits (86), Expect = 0.064
Identities = 42/145 (28%), Positives = 49/145 (33%), Gaps = 16/145 (11%)
Query: 478 PDARQLWDSPETAPAARTPQSPAPCVLLRAQRSLAPEPKEPLIPASPKAEPIWELPTRAP 537
P + P++ P P +P P R P P P P SP P R
Sbjct: 171 PPRPDVGSKPDSIPPP-VPSTPRPIQSSPHNRGSPPVPGGPRQP-SPGPTPPPFPGNRGT 228
Query: 538 RLSIGDLDFSDLGEDEDQDMLNVESVEAGKDIPAPSPPLPLLSGVPPPPPLPP---PPPI 594
L G + S L S P P P L PPPPP P P
Sbjct: 229 ALGGGSIRQSPLSS----------SSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIH 278
Query: 595 KGPFPPPPPLPLAAPLPHSVPDSSA 619
+ PPPPP P+P S P SA
Sbjct: 279 REAVPPPPPQNNKPPVP-STPRPSA 302
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 58.2 bits (139), Expect = 5e-08
Identities = 43/151 (28%), Positives = 61/151 (40%), Gaps = 10/151 (6%)
Query: 480 ARQLWDSPETAPAARTPQSPAPCVLLRAQRSLAPEPKEPLIPASPKAEPIWELPTRAP-- 537
+R L D P P P P + A P+ +P +P++P+ + P P
Sbjct: 257 SRALDDKPPPPPP---PVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPP 313
Query: 538 -RLSIGDLDFSDLGEDEDQDMLNVESVEAGKDIPAPSP----PLPLLSGVPPPPPLPPPP 592
R L S G DE + + P PSP PLP PPPP+ PP
Sbjct: 314 SRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPP 373
Query: 593 PIKGPFPPPPPLPLAAPLPHSVPDSSALPTK 623
GP PPPPP+ ++P + LP++
Sbjct: 374 GRSGPLPPPPPVSRNGSTSRALPATPQLPSR 404
Score = 42.4 bits (98), Expect = 0.003
Identities = 62/241 (25%), Positives = 87/241 (36%), Gaps = 31/241 (12%)
Query: 376 RAPEPGPTGPASPVGPTSSTGPALLTGPA-SSPVGPPSGLQASVNLFPTISVA------- 427
R P PGPT P P + G AL G SP+ S L PT S A
Sbjct: 211 RQPSPGPTPPPFP----GNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPP 266
Query: 428 PSADTSSERSIYKARFLENVAAAETEKQVALAQGRAETLAGAMPNEAGGHPDARQLWDSP 487
P + SI++ + + V + + P P L P
Sbjct: 267 PPPPVGNRPSIHREA-VPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPL--PP 323
Query: 488 ETAPAARTPQSPAPCVLLRAQRSLAPEPKEPLIPASPKAEPIWELPTRAPRLSIGDLDFS 547
++ TP+ P QR+L+ P +P+ ++ P+ P+ P + D
Sbjct: 324 SSSGNDETPRLP--------QRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGR 375
Query: 548 DLGEDEDQDMLNVESVEAGKDIPAPSPPLPLLSGVPPP-----PPLPPPPPIKGPFPPPP 602
+ S + +PA +P LP SGV P PPLPP P G PPPP
Sbjct: 376 SGPLPPPPPVSRNGSTS--RALPA-TPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPP 432
Query: 603 P 603
P
Sbjct: 433 P 433
Score = 37.7 bits (86), Expect = 0.064
Identities = 42/145 (28%), Positives = 49/145 (33%), Gaps = 16/145 (11%)
Query: 478 PDARQLWDSPETAPAARTPQSPAPCVLLRAQRSLAPEPKEPLIPASPKAEPIWELPTRAP 537
P + P++ P P +P P R P P P P SP P R
Sbjct: 171 PPRPDVGSKPDSIPPP-VPSTPRPIQSSPHNRGSPPVPGGPRQP-SPGPTPPPFPGNRGT 228
Query: 538 RLSIGDLDFSDLGEDEDQDMLNVESVEAGKDIPAPSPPLPLLSGVPPPPPLPP---PPPI 594
L G + S L S P P P L PPPPP P P
Sbjct: 229 ALGGGSIRQSPLSS----------SSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIH 278
Query: 595 KGPFPPPPPLPLAAPLPHSVPDSSA 619
+ PPPPP P+P S P SA
Sbjct: 279 REAVPPPPPQNNKPPVP-STPRPSA 302
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.133 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,213,951
Number of Sequences: 37866
Number of extensions: 3046654
Number of successful extensions: 60373
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 637
Number of HSP's successfully gapped in prelim test: 956
Number of HSP's that attempted gapping in prelim test: 24482
Number of HSP's gapped (non-prelim): 18587
length of query: 1164
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1051
effective length of database: 13,968,660
effective search space: 14681061660
effective search space used: 14681061660
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.