Guide to the Human Genome
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Search of human proteins with 239751532

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239751532 PREDICTED: similar to vacuolar protein sorting 53
(yeast) (predicted) [Homo sapiens]
         (188 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239751532 PREDICTED: similar to vacuolar protein sorting 53 (...   379   e-106
gi|239746043 PREDICTED: hypothetical protein XP_002343642 [Homo ...   376   e-105
gi|189491744 vacuolar protein sorting 53 isoform 1 [Homo sapiens]     118   3e-27
gi|154707916 glutathione S-transferase, C-terminal domain contai...    30   1.6  
gi|149588660 glutathione S-transferase, C-terminal domain contai...    30   1.6  
gi|94536864 hypothetical protein LOC138724 isoform D [Homo sapiens]    29   2.1  
gi|94536862 hypothetical protein LOC138724 isoform C [Homo sapiens]    29   2.1  
gi|94536860 hypothetical protein LOC138724 isoform B [Homo sapiens]    29   2.1  
gi|94681096 hypothetical protein LOC138724 isoform A [Homo sapiens]    29   2.1  
gi|223278403 glutamate receptor, ionotropic, delta 2 (Grid2) int...    28   3.6  
gi|116812632 hypothetical protein LOC154743 [Homo sapiens]             28   3.6  
gi|27477041 adaptor-related protein complex 2, alpha 2 subunit [...    28   6.1  
gi|18390344 ATR interacting protein isoform 2 [Homo sapiens]           28   6.1  
gi|18390347 ATR interacting protein isoform 1 [Homo sapiens]           28   6.1  
gi|31542246 kelch-like 36 [Homo sapiens]                               28   6.1  
gi|71164892 gremlin 2 precursor [Homo sapiens]                         28   6.1  
gi|153251865 hypothetical protein LOC84226 [Homo sapiens]              28   6.1  
gi|52218826 olfactory receptor, family 1, subfamily J, member 4 ...    27   7.9  

>gi|239751532 PREDICTED: similar to vacuolar protein sorting 53
           (yeast) (predicted) [Homo sapiens]
          Length = 188

 Score =  379 bits (973), Expect = e-106
 Identities = 188/188 (100%), Positives = 188/188 (100%)

Query: 1   MEGTREIHTPKLLEREQRHISSPGLPSGIAAPDPFGKGIQRCRWLLAEVVTAPQELLVVL 60
           MEGTREIHTPKLLEREQRHISSPGLPSGIAAPDPFGKGIQRCRWLLAEVVTAPQELLVVL
Sbjct: 1   MEGTREIHTPKLLEREQRHISSPGLPSGIAAPDPFGKGIQRCRWLLAEVVTAPQELLVVL 60

Query: 61  VDNYIKLFTDCNTEAFRKILDMKGMKRNKQSSMLEFLHLPLPMLPLGVESSSSLSLMPPT 120
           VDNYIKLFTDCNTEAFRKILDMKGMKRNKQSSMLEFLHLPLPMLPLGVESSSSLSLMPPT
Sbjct: 61  VDNYIKLFTDCNTEAFRKILDMKGMKRNKQSSMLEFLHLPLPMLPLGVESSSSLSLMPPT 120

Query: 121 PEQELSGICKLIKKRLLKSSFSIGDFRRVEQLGSSRASPITFGLFWPHGVVALDPKIFKG 180
           PEQELSGICKLIKKRLLKSSFSIGDFRRVEQLGSSRASPITFGLFWPHGVVALDPKIFKG
Sbjct: 121 PEQELSGICKLIKKRLLKSSFSIGDFRRVEQLGSSRASPITFGLFWPHGVVALDPKIFKG 180

Query: 181 LKVYGKKP 188
           LKVYGKKP
Sbjct: 181 LKVYGKKP 188


>gi|239746043 PREDICTED: hypothetical protein XP_002343642 [Homo
           sapiens]
          Length = 188

 Score =  376 bits (966), Expect = e-105
 Identities = 187/188 (99%), Positives = 187/188 (99%)

Query: 1   MEGTREIHTPKLLEREQRHISSPGLPSGIAAPDPFGKGIQRCRWLLAEVVTAPQELLVVL 60
           MEGTREIHTPKLL REQRHISSPGLPSGIAAPDPFGKGIQRCRWLLAEVVTAPQELLVVL
Sbjct: 1   MEGTREIHTPKLLGREQRHISSPGLPSGIAAPDPFGKGIQRCRWLLAEVVTAPQELLVVL 60

Query: 61  VDNYIKLFTDCNTEAFRKILDMKGMKRNKQSSMLEFLHLPLPMLPLGVESSSSLSLMPPT 120
           VDNYIKLFTDCNTEAFRKILDMKGMKRNKQSSMLEFLHLPLPMLPLGVESSSSLSLMPPT
Sbjct: 61  VDNYIKLFTDCNTEAFRKILDMKGMKRNKQSSMLEFLHLPLPMLPLGVESSSSLSLMPPT 120

Query: 121 PEQELSGICKLIKKRLLKSSFSIGDFRRVEQLGSSRASPITFGLFWPHGVVALDPKIFKG 180
           PEQELSGICKLIKKRLLKSSFSIGDFRRVEQLGSSRASPITFGLFWPHGVVALDPKIFKG
Sbjct: 121 PEQELSGICKLIKKRLLKSSFSIGDFRRVEQLGSSRASPITFGLFWPHGVVALDPKIFKG 180

Query: 181 LKVYGKKP 188
           LKVYGKKP
Sbjct: 181 LKVYGKKP 188


>gi|189491744 vacuolar protein sorting 53 isoform 1 [Homo sapiens]
          Length = 832

 Score =  118 bits (295), Expect = 3e-27
 Identities = 68/103 (66%), Positives = 75/103 (72%), Gaps = 4/103 (3%)

Query: 37  KGIQRCRWLLAEVVTAPQELLVVLVDNYIKLFTDCNTEAFRKILDMKGMKRNKQSSMLEF 96
           KG+ R   +L +VV AP E LVV VDNYIKL TDCNTE F+KILDMKG+KR++QSSMLE 
Sbjct: 731 KGMTRAEMIL-KVVMAPHEPLVVFVDNYIKLLTDCNTETFQKILDMKGLKRSEQSSMLEL 789

Query: 97  LHLPLPMLPLGVESSSSLSLMPPTPEQELSGIC---KLIKKRL 136
           L   LP  P G ESS SLSL  PTPEQE S I    KLIKKRL
Sbjct: 790 LRQRLPAPPSGAESSGSLSLTAPTPEQESSRIRKLEKLIKKRL 832


>gi|154707916 glutathione S-transferase, C-terminal domain
           containing isoform 2 [Homo sapiens]
          Length = 546

 Score = 29.6 bits (65), Expect = 1.6
 Identities = 28/118 (23%), Positives = 49/118 (41%), Gaps = 8/118 (6%)

Query: 10  PKLLEREQRHISSPGLPSGIAAPDPFGKGIQRCRWLLAEVVTAP--QELLVVLVDNYIKL 67
           P    RE  HI              F +G+    + LA++V  P     LV++   + + 
Sbjct: 165 PATTNREPSHIRKAKASDLPPLEHVFAEGLY---FTLADIVLLPCIHHFLVIISRKFSEK 221

Query: 68  FTDCNTEA--FRKILDMKGMKRNKQSSMLEFLHLPLPMLPLGVESSSSLSLMPPTPEQ 123
             +    A  +++I ++ G+K       ++FLHLP  +L    E   +L  +P   EQ
Sbjct: 222 LVEFPLLASWYQRIQEVPGVKTAASKCGIQFLHLP-KLLTTSTEQHPNLCEVPGVEEQ 278


>gi|149588660 glutathione S-transferase, C-terminal domain
           containing isoform 1 [Homo sapiens]
          Length = 633

 Score = 29.6 bits (65), Expect = 1.6
 Identities = 28/118 (23%), Positives = 49/118 (41%), Gaps = 8/118 (6%)

Query: 10  PKLLEREQRHISSPGLPSGIAAPDPFGKGIQRCRWLLAEVVTAP--QELLVVLVDNYIKL 67
           P    RE  HI              F +G+    + LA++V  P     LV++   + + 
Sbjct: 252 PATTNREPSHIRKAKASDLPPLEHVFAEGLY---FTLADIVLLPCIHHFLVIISRKFSEK 308

Query: 68  FTDCNTEA--FRKILDMKGMKRNKQSSMLEFLHLPLPMLPLGVESSSSLSLMPPTPEQ 123
             +    A  +++I ++ G+K       ++FLHLP  +L    E   +L  +P   EQ
Sbjct: 309 LVEFPLLASWYQRIQEVPGVKTAASKCGIQFLHLP-KLLTTSTEQHPNLCEVPGVEEQ 365


>gi|94536864 hypothetical protein LOC138724 isoform D [Homo sapiens]
          Length = 1031

 Score = 29.3 bits (64), Expect = 2.1
 Identities = 14/44 (31%), Positives = 21/44 (47%)

Query: 10  PKLLEREQRHISSPGLPSGIAAPDPFGKGIQRCRWLLAEVVTAP 53
           P L E  +   + PGLP G+  P    +     RW + E++T P
Sbjct: 685 PTLAEAVKIERTHPGLPKGVTCPGVKAEAPLSQRWTVPELLTHP 728


>gi|94536862 hypothetical protein LOC138724 isoform C [Homo sapiens]
          Length = 1006

 Score = 29.3 bits (64), Expect = 2.1
 Identities = 14/44 (31%), Positives = 21/44 (47%)

Query: 10  PKLLEREQRHISSPGLPSGIAAPDPFGKGIQRCRWLLAEVVTAP 53
           P L E  +   + PGLP G+  P    +     RW + E++T P
Sbjct: 660 PTLAEAVKIERTHPGLPKGVTCPGVKAEAPLSQRWTVPELLTHP 703


>gi|94536860 hypothetical protein LOC138724 isoform B [Homo sapiens]
          Length = 1044

 Score = 29.3 bits (64), Expect = 2.1
 Identities = 14/44 (31%), Positives = 21/44 (47%)

Query: 10  PKLLEREQRHISSPGLPSGIAAPDPFGKGIQRCRWLLAEVVTAP 53
           P L E  +   + PGLP G+  P    +     RW + E++T P
Sbjct: 698 PTLAEAVKIERTHPGLPKGVTCPGVKAEAPLSQRWTVPELLTHP 741


>gi|94681096 hypothetical protein LOC138724 isoform A [Homo sapiens]
          Length = 1079

 Score = 29.3 bits (64), Expect = 2.1
 Identities = 14/44 (31%), Positives = 21/44 (47%)

Query: 10  PKLLEREQRHISSPGLPSGIAAPDPFGKGIQRCRWLLAEVVTAP 53
           P L E  +   + PGLP G+  P    +     RW + E++T P
Sbjct: 733 PTLAEAVKIERTHPGLPKGVTCPGVKAEAPLSQRWTVPELLTHP 776


>gi|223278403 glutamate receptor, ionotropic, delta 2 (Grid2)
           interacting protein [Homo sapiens]
          Length = 1211

 Score = 28.5 bits (62), Expect = 3.6
 Identities = 21/83 (25%), Positives = 37/83 (44%), Gaps = 5/83 (6%)

Query: 77  RKILDMKGMKRNKQSSMLEFLHLPLPMLPLGVESSSSLSLMPPTPEQELSGICKLIKKRL 136
           R+ L  +G++        E   +PLP++P G   +   + +P TP  ++        +  
Sbjct: 504 RRSLRSQGLEAGLSCGPSECPEMPLPLIP-GERQAGDGTSLPETPNPKMMSAVYAELESR 562

Query: 137 LKSSFSIGDFRRVEQLGSSRASP 159
           L SSF      ++  +  SRASP
Sbjct: 563 LNSSFK----GKMGTVSKSRASP 581


>gi|116812632 hypothetical protein LOC154743 [Homo sapiens]
          Length = 405

 Score = 28.5 bits (62), Expect = 3.6
 Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 7/39 (17%)

Query: 118 PPTPEQE-------LSGICKLIKKRLLKSSFSIGDFRRV 149
           PP  EQE       LSG+ K + +RL K    +GDF ++
Sbjct: 22  PPPREQERKLEQEKLSGVVKSVHRRLRKKYREVGDFDKI 60


>gi|27477041 adaptor-related protein complex 2, alpha 2 subunit
           [Homo sapiens]
          Length = 939

 Score = 27.7 bits (60), Expect = 6.1
 Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 6/95 (6%)

Query: 59  VLVDNYIKLFTDCNTEAFRKILDMKGMKRNKQSSMLEFLHLPLPMLPLGVESSSS----- 113
           +L+  YIK F +   E    I D+       +++ +E     +  L L   +S+      
Sbjct: 539 LLLSTYIK-FVNLFPEVKPTIQDVLRSDSQLRNADVELQQRAVEYLRLSTVASTDILATV 597

Query: 114 LSLMPPTPEQELSGICKLIKKRLLKSSFSIGDFRR 148
           L  MPP PE+E S + KL KK+   +   + D +R
Sbjct: 598 LEEMPPFPERESSILAKLKKKKGPSTVTDLEDTKR 632


>gi|18390344 ATR interacting protein isoform 2 [Homo sapiens]
          Length = 764

 Score = 27.7 bits (60), Expect = 6.1
 Identities = 24/90 (26%), Positives = 35/90 (38%), Gaps = 11/90 (12%)

Query: 74  EAFRKILDMKGMKRNKQSSMLEFLHLPLPMLP-----------LGVESSSSLSLMPPTPE 122
           EA +  +D    + N Q S+L  L L  P++P              ES +   L PP   
Sbjct: 292 EAQKSFVDSWRQRSNTQGSILINLLLKQPLIPGSSLSLCHLLSSSSESPAGTPLQPPGFG 351

Query: 123 QELSGICKLIKKRLLKSSFSIGDFRRVEQL 152
             L+G+  L        SFS+   R  + L
Sbjct: 352 STLAGMSGLRTTGSYDGSFSLSALREAQNL 381


>gi|18390347 ATR interacting protein isoform 1 [Homo sapiens]
          Length = 791

 Score = 27.7 bits (60), Expect = 6.1
 Identities = 24/90 (26%), Positives = 35/90 (38%), Gaps = 11/90 (12%)

Query: 74  EAFRKILDMKGMKRNKQSSMLEFLHLPLPMLP-----------LGVESSSSLSLMPPTPE 122
           EA +  +D    + N Q S+L  L L  P++P              ES +   L PP   
Sbjct: 292 EAQKSFVDSWRQRSNTQGSILINLLLKQPLIPGSSLSLCHLLSSSSESPAGTPLQPPGFG 351

Query: 123 QELSGICKLIKKRLLKSSFSIGDFRRVEQL 152
             L+G+  L        SFS+   R  + L
Sbjct: 352 STLAGMSGLRTTGSYDGSFSLSALREAQNL 381


>gi|31542246 kelch-like 36 [Homo sapiens]
          Length = 616

 Score = 27.7 bits (60), Expect = 6.1
 Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 8/67 (11%)

Query: 40  QRCRWLLAEVVTAPQE--------LLVVLVDNYIKLFTDCNTEAFRKILDMKGMKRNKQS 91
           QR R L  +VV    E        LL V  D +  +FT    EAF+K +++ G       
Sbjct: 39  QRLRGLFCDVVLVADEQRVPAHRNLLAVCSDYFNSMFTIGMREAFQKEVELIGASYIGLK 98

Query: 92  SMLEFLH 98
           ++++FL+
Sbjct: 99  AVVDFLY 105


>gi|71164892 gremlin 2 precursor [Homo sapiens]
          Length = 168

 Score = 27.7 bits (60), Expect = 6.1
 Identities = 21/66 (31%), Positives = 35/66 (53%), Gaps = 8/66 (12%)

Query: 26 PSGIAAPDPFGKGI----QRCRWLLAEVVTAPQELLVVLVDNYIKLFTD-CNTEAFRKIL 80
          P+G A P P+  G     +R +  + EV+ + QE LVV    Y+K  +D C T+  R+ +
Sbjct: 26 PAG-AIPSPYKDGSSNNSERWQHQIKEVLASSQEALVVTERKYLK--SDWCKTQPLRQTV 82

Query: 81 DMKGMK 86
            +G +
Sbjct: 83 SEEGCR 88


>gi|153251865 hypothetical protein LOC84226 [Homo sapiens]
          Length = 1984

 Score = 27.7 bits (60), Expect = 6.1
 Identities = 14/46 (30%), Positives = 22/46 (47%)

Query: 3   GTREIHTPKLLEREQRHISSPGLPSGIAAPDPFGKGIQRCRWLLAE 48
           G +   T +L  + Q H+ SPG+ SG+    P    +   +WL  E
Sbjct: 369 GVQVEKTLQLTPKPQHHVGSPGIISGLGHQVPESVNLTCKQWLQME 414


>gi|52218826 olfactory receptor, family 1, subfamily J, member 4
           [Homo sapiens]
          Length = 313

 Score = 27.3 bits (59), Expect = 7.9
 Identities = 13/21 (61%), Positives = 15/21 (71%)

Query: 85  MKRNKQSSMLEFLHLPLPMLP 105
           MKR  QSS+ EFL L LP+ P
Sbjct: 1   MKRENQSSVSEFLLLDLPIWP 21


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.139    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,761,489
Number of Sequences: 37866
Number of extensions: 344647
Number of successful extensions: 995
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 985
Number of HSP's gapped (non-prelim): 18
length of query: 188
length of database: 18,247,518
effective HSP length: 96
effective length of query: 92
effective length of database: 14,612,382
effective search space: 1344339144
effective search space used: 1344339144
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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